ライフサイエンスコーパス: dismutase

1 kers (Glutathione peroxidase, and superoxide dismutase).

2 , with a rate constant similar to superoxide dismutase.

3 uperoxide to hydrogen peroxide by superoxide dismutase.

4 hich is crucial for NPs' function as nitrite dismutase.

5 o-STAT3 and loss of extracellular superoxide dismutase.

6 whereas it enhances expression of superoxide dismutase.

7 strongly donating thiolates in Ni superoxide dismutase.

8 her Tar DNA-binding protein 43 or superoxide dismutase.

9 tionally redundant SoxR-regulated superoxide dismutase.

10 e G985R and G93A mutated forms of superoxide dismutase 1 (linked to familial amyotrophic lateral scle

11 interferon-gamma (IFN-gamma) and superoxide dismutase 1 (SOD) (P < 0.05).

12 ation sphere at the core of human superoxide dismutase 1 (SOD) with 0.7 pm precision.

13 by expression of a mutant form of superoxide dismutase 1 (SOD1 G93A) that causes astrocyte dysfunctio

14 expressing a mutant form of human superoxide dismutase 1 (SOD1(G93A) ).

15 Mutant superoxide dismutase 1 (SOD1(G93A)) expression in astrocytes is sel

16 We administered fenofibrate to superoxide dismutase 1 (SOD1(G93A)) mice daily prior to any detecta

17 se model of ALS expressing mutant superoxide dismutase 1 (SOD1(G93A)), we show that motor neurons for

18 s such as ALS, where mutations of superoxide dismutase 1 (SOD1) account for about 20% of the inherite

19 ndrial dysfunction, and disturbed superoxide dismutase 1 (SOD1) and Keap1/Nrf2 antioxidant responses

20 activity of antioxidant enzymes, superoxide dismutase 1 (SOD1) and peroxiredoxin-4 (PRDX4) during hy

21 Mutations in the gene encoding superoxide dismutase 1 (SOD1) are the second most common cause of f

22 Non-natively folded variants of superoxide dismutase 1 (SOD1) are thought to contribute to the path

23 Mutations in superoxide dismutase 1 (SOD1) cause 15-20% of familial amyotrophic

24 Mutations in Cu-Zn superoxide dismutase 1 (SOD1) cause familial forms of amyotrophic l

25 opper-dependent activation of the superoxide dismutase 1 (SOD1) during spore germination.

26 tients harboring mutations in the superoxide dismutase 1 (SOD1) gene.

27 h 20% are due to mutations in the superoxide dismutase 1 (SOD1) gene.

28 ic mouse models expressing mutant superoxide dismutase 1 (SOD1) have been critical in furthering our

29 the sequence of the gene encoding superoxide dismutase 1 (SOD1) have been linked to toxic protein agg

30 ty and release of a model enzyme, superoxide dismutase 1 (SOD1) immobilized by polyion coupling on di

31 ALS-associated mutations in Cu/Zn superoxide dismutase 1 (SOD1) impair axonal transport of mitochondr

32 ructure of a cytotoxic segment of superoxide dismutase 1 (SOD1) in its oligomeric state.

33 ins amyloid-beta (Abeta), tau and superoxide dismutase 1 (SOD1) in the cerebrospinal fluid of healthy

34 injection of oligomers of mutant superoxide dismutase 1 (SOD1) into the cytoplasm of invertebrate ne

35 ne (E40K) residue substitution in superoxide dismutase 1 (SOD1) is associated with canine degenerativ

36 Superoxide dismutase 1 (SOD1) is the principal cytoplasmic superoxi

37 that mediates the degradation of superoxide dismutase 1 (SOD1) messenger RNA to reduce SOD1 protein

38 creasing metabolism in the mutant superoxide dismutase 1 (SOD1) mouse model of ALS (G93A SOD1) would

39 re we show that, in vitro, mutant superoxide dismutase 1 (SOD1) mouse oligodendrocytes induce WT moto

40 ateral sclerosis (ALS)-associated superoxide dismutase 1 (SOD1) mutant protein induces changes in HSP

41 nd neutralize misfolded and toxic superoxide dismutase 1 (SOD1) mutant proteins may find application

42 Superoxide dismutase 1 (SOD1) mutations account for up to 20% of fa

43 d by transgenic overexpression of superoxide dismutase 1 (SOD1) or an SOD1 mimetic.

44 al sclerosis-associated cytosolic superoxide dismutase 1 (SOD1) protein between motor neurons could b

45 erosis (ALS)-causing mutations in superoxide dismutase 1 (SOD1) provokes noncell autonomous paralytic

46 G85R is a mutant version of Cu/Zn superoxide dismutase 1 (SOD1) that is unable to reach native form a

47 examined potential inhibitors of superoxide dismutase 1 (SOD1) using ThT-fluorescence including the

48 nd mutations in the gene encoding superoxide dismutase 1 (SOD1) were treated with a single intratheca

49 eral sclerosis (ALS) mouse model, superoxide dismutase 1 (SOD1)(G93A), revealed that these EVs contai

50 Superoxide dismutase 1 (SOD1), a key antioxidant enzyme in human ce

51 ence lacking cytoplasmic protein, superoxide dismutase 1 (SOD1), and its mutant form linked to amyotr

52 y oligomers of mutant human Cu/Zn superoxide dismutase 1 (SOD1), which are associated with motor neur

53 For mutated superoxide dismutase 1 (SOD1), which causes familial amyotrophic la

54 ently during aggregation of human superoxide dismutase 1 (SOD1), which is known to form misfolded agg

55 erosis-associated protein variant superoxide dismutase 1 (SOD1)-A4V, whereas HSPA1L enhanced its aggr

56 enotypes in preclinical stages of superoxide dismutase 1 (SOD1)-mutant-mediated disease.

57 by mutations in the gene encoding superoxide dismutase 1 (SOD1).

58 iver, including downregulation of superoxide dismutase 1 (Sod1).

59 reactive oxygen species scavenger superoxide dismutase 1 (SOD1).

60 DNA-binding protein (TDP-43) and superoxide dismutase 1 (SOD1).

61 -lacking Acb1 and the antioxidant superoxide dismutase 1 (SOD1).

62 tures from a mutant form of human superoxide dismutase 1 (SOD1G93A) mouse model of ALS allow the dete

63 Co-expression of wild-type human superoxide dismutase 1 (WT-hSOD1) with ALS mutant hSOD1 accelerates

64 cetin increased the expression of superoxide dismutase 1 and 2, and reduced the levels of oxidative s

65 ression of free radical scavenger superoxide dismutase 1 and aldehyde dehydrogenase 2 was reduced, wh

66 ownstream of Nrf2, levels of oPMN superoxide dismutase 1 and catalase were decreased in severe CP, de

67 lation of the antioxidant enzymes superoxide dismutase 1 and catalase, and activation of the pro-oxid

68 and translation of antioxidants, superoxide dismutase 1 and glutathione peroxidase-1, were significa

69 ochondrial dysfunction, disturbed superoxide dismutase 1 and Keap1/Nrf2 antioxidant responses, over-p

70 op DM are homozygous for a common superoxide dismutase 1 gene (SOD1) mutation.

71 ant FUS (Fused in sarcoma), SOD1 (superoxide dismutase 1), TDP43 (TAR DNA-binding protein 43), and ta

72 ocytes isolated from mutant human superoxide dismutase 1-overexpressing mice as well as human post-mo

73 hich astrocytes expressing mutant superoxide dismutase-1 (mutSOD1) kill wild-type motor neurons (MNs)

74 Here, we show superoxide dismutase-1 (SOD-1), an enzyme that converts superoxide

75 icle investigates how the rate of superoxide dismutase-1 (SOD1) fibrillization is affected by 12 diff

76 e acylation of lysine residues in superoxide dismutase-1 (SOD1) has been previously shown to decrease

77 Superoxide dismutase-1 (SOD1) maturation comprises a string of post

78 cases result from impaired mutant superoxide dismutase-1 (SOD1) maturation.

79 setup and use the specificity of superoxide dismutase-1 (SOD1) to show, for the first time, that H2O

80 ice expressing the ALS-associated superoxide dismutase-1 (SOD1)(G93A) mutant decreased spinal motoneu

81 nced the association of DJ-1 with superoxide dismutase-1 (SOD1), paralleled by significant increases

82 of familial ALS expressing mutant superoxide dismutase-1 (SOD1), TAR DNA-binding protein 43 (TDP-43),

83 s has been shown for mutations in superoxide dismutase-1 (SOD1).

84 e oxidative species scavenging by superoxide dismutase-1 and superoxide dismutase-2.

85 ce with high numbers of the Cu/Zn superoxide dismutase-1 G93A transgene (SOD1(G93A) G1H) have become

86 ymes (heme oxygenase-1, catalase, superoxide dismutase-1) in a time-dependent manner.

87 ulate intracellular aggregates of superoxide dismutase-1.

88 n messenger RNA of shared targets superoxide dismutase 2 (P <= 0.001) and heme oxygenase 1 (P <= 0.00

89 of Sirt1 increased mitochondrial superoxide dismutase 2 (Sod2) acetylation of lysine residue 68, the

90 active oxygen species and reduced superoxide dismutase 2 (SOD2) activity.

91 activity of sirtuin 3 to inhibit superoxide dismutase 2 (SOD2) activity.

92 rms of stress, or enzymes such as superoxide dismutase 2 (SOD2) and catalase, which directly detoxify

93 of the oxidative stress enzymes, superoxide dismutase 2 (SOD2) and catalase.

94 ased acetylation of mitochondrial superoxide dismutase 2 (SOD2) and isocitrate dehydrogenase 2 (IDH2)

95 ed that inhibitory acetylation of superoxide dismutase 2 (SOD2) at K122 was increased in WT (but not

96 mitochondrial antioxidant enzyme, superoxide dismutase 2 (SOD2) because of hyperacetylation.

97 d induced a rapid upregulation of superoxide dismutase 2 (SOD2) expression and a delayed upregulation

98 protein 70 (hsp70) interacts with superoxide dismutase 2 (SOD2) in the cytosol after synthesis to tra

99 Superoxide dismutase 2 (SOD2) is a crucial antioxidative enzyme tha

100 Mitochondrial superoxide dismutase 2 (SOD2) is frequently overexpressed in oral a

101 Ectopic expression of superoxide dismutase 2 (SOD2) reduced ROS and preserved viability o

102 ology, elevated protein levels of superoxide dismutase 2 (SOD2), and increased levels of peroxisome p

103 and increased antioxidant enzymes superoxide dismutase 2 (SOD2), catalase, glutathione peroxidase 1 (

104 mitochondrial proteins, including superoxide dismutase 2 (SOD2), depended on 4E-BP1/2.

105 itrate dehydrogenase 2 (IDH2) and superoxide dismutase 2 (SOD2).

106 oxides, had reduced activities of superoxide dismutase 2 and catalase, and were hypersensitive to hyd

107 aused significant upregulation of superoxide dismutase 2 and heme oxygenase 1 protein following hypox

108 the levels of peroxiredoxin 3 and superoxide dismutase 2 in adipose tissue, indicating increased mito

109 ylation of the antioxidant enzyme superoxide dismutase 2 in muscle but not the liver of MCD(-/-) mice

110 tive damage markers, and of SOD2 (superoxide dismutase 2), PGC1alpha [peroxisome proliferator-activat

111 in rice (Oryza sativa) (FSD2, Fe-superoxide dismutase 2).

112 ms were discovered in relation to superoxide dismutase 2, ATP binding cassette subfamily A member 1,

113 A) isocitrate dehydrogenase 2 and superoxide dismutase 2, concomitant with increases in citrate synth

114 ated with a reduced ratio of mROS/superoxide dismutase 2.

115 regulator of oxidative stress and superoxide dismutase 2.

116 OXO3a) and a downstream effector, superoxide dismutase 2.

117 et genes (including mitochondrial superoxide dismutase), (2) enhanced phagocytic activity toward red

118 There was a 34% increase in superoxide dismutase-2 activity, along with a 3.5-fold increase in

119 al and vascular oxidative stress (superoxide dismutase-2), neuroinflammation (astroglial and microgli

120 d enhanced lung concentrations of superoxide dismutase-2, thereby reducing lung tissue reactive oxida

121 ing by superoxide dismutase-1 and superoxide dismutase-2.

122 dy, we investigated the effect of superoxide dismutase 3 (SOD3) on LL-37- or KLK-5-induced skin infla

123 lysis with higher MMP-2 and lower superoxide dismutase 3 gene expression, independent of age and aort

124 P-2), MMP-14, endoglin (ENG), and superoxide dismutase 3 in ascending aorta samples from 50 tricuspid

125 .6% of normoxic control), reduced superoxide dismutase (60.7 +/- 6.3%), increased phosphodiesterase t

126 omolecules, e.g., of enzyme Cu/Zn-superoxide dismutase, abnormal aggregation of which is linked to am

127 further increases in catalase and superoxide dismutase activities, which led to a significant reducti

128 Superoxide dismutase activity in human blood plasma mirrored these

129 ype levels of manganese-dependent superoxide dismutase activity in the presence of calprotectin.

130 mixed bread, a marked decrease in superoxide dismutase activity was found.

131 The superoxide dismutase activity was relatively insensitive.

132 stinct from the established MnSOD superoxide dismutase activity.

133 ctivity of the antioxidant enzyme superoxide dismutase and a different regulation of the glutathione

134 pecies, and reduced activities of superoxide dismutase and catalase enzymes.

135 Furthermore, the synthetic superoxide dismutase and catalase mimetic EUK-134 also ablated the

136 restored NO production, increased superoxide dismutase and catalase, and suppressed NADPH oxidase and

137 including one of three copies of superoxide dismutase and five novel members of its regulon that cou

138 h A lowered DON-induced catalase, superoxide dismutase and glutathione peroxidase antioxidant enzyme

139 ynamin related protein, manganese superoxide dismutase and Lon protease, respectively, were generated

140 higher activities of antioxidant (superoxide dismutase and peroxidase) and defense enzymes (polypheno

141 itochondrial manganese-containing superoxide dismutase and peroxiredoxin 5 were only upregulated by P

142 GR and up-regulation of manganese superoxide dismutase and reduced glutathione levels.

143 In B. asiatica, high superoxide dismutase and significantly enhanced (p < 0.05) peroxida

144 ion, oxidative stress protection (superoxide dismutases) and iron and nitrogen metabolism varied amon

145 omoted antioxidant enzymes (i.e., superoxide dismutase, and catalase), strong DPPH-scavenging activit

146 including glutathione peroxidase, superoxide dismutase, and catalase, were evaluated in each of the i

147 ldehyde (MDA), nitric oxide (NO), superoxide dismutase, and glutathione peroxidase (GPX) levels in se

148 e proteins such as cyclophilin D, superoxide dismutase, and PEPCK1 were not deacetylated.

149 ultaneously possessing catalase-, superoxide dismutase-, and glutathione peroxidase-mimicking enzyme

150 aracterized by higher activity of superoxide dismutase, ascorbate peroxidase and phenylalanine ammoni

151 ) is produced, via superoxide and superoxide dismutase, by electron transport in chloroplasts and mit

152 a new human recombinant manganese superoxide dismutase can enter cells and carry molecules.

153 mol L(-1) treatment showed higher superoxide dismutase, catalase and ascorbate peroxidase activities

154 and S.EPS significantly improved superoxide dismutase, catalase and glutathione peroxidase activitie

155 TNF-alpha) and oxidative stress (superoxide dismutase, catalase, glutathione peroxidase, lipidic and

156 exaggerated in the presence of a superoxide dismutase/catalase mimetic.

157 The copper chaperone for superoxide dismutase (Ccs1) activates immature copper-zinc superoxi

158 mutations in Copper Chaperone for Superoxide Dismutase (CCSD) resulted in enhanced susceptibility.

159 s have shown that levels of Cu/Zn superoxide dismutase (CSD) are down-regulated by miR398.

160 for miR398 in an isoform of Cu/Zn superoxide dismutase (CSD1) is eliminated by alternative splicing t

161 genesis (RNA-binding protein FUS, superoxide dismutase Cu-Zn and neurofilaments light polypeptide) al

162 droxy-2'-deoxyguanosine (8-OHdG), superoxide dismutase (Cu-Zn SOD), and thiobarbituric acid reactive

163 The previous studies on superoxide dismutases (Cu, Zn-SODs) showed that the dimeric structu

164 CuZn-superoxide dismutase (CuZn-SOD) and ascorbate peroxidase (APX) cons

165 reduction using PTR, homodimeric superoxide dismutase/CuZn (31.4 kDa) was subjected to PTR in order

166 Ras-related nuclear, p53, PEPCK1, superoxide dismutase, cyclophilin D, and Hsp10, and analyzed the de

167 meric beta-lactoglobulin, dimeric superoxide dismutase, dimeric and tetrameric concanavalin A, and he

168 acids, and has an iron/manganese superoxide dismutase domain.

169 7 is able to induce extracellular superoxide dismutase during differentiation of monocytes but not in

170 extracellular antioxidant enzyme superoxide dismutase (EC-SOD) as a novel substrate of CatA, which d

171 x-binding domain of extracellular superoxide dismutase (EC-SOD), with arginine to glycine substitutio

172 h varying levels of extracellular superoxide dismutase (ecSOD) activity, we have recently shown that

173 e training enhances extracellular superoxide dismutase (EcSOD) expression in skeletal muscle and elic

174 ssing lung-specific extracellular superoxide dismutase (ecSOD) were exposed to HEPA-filtered air or t

175 oxidase and increased activity of superoxide dismutase enzyme.

176 Activities of catalase and superoxide dismutase enzymes, levels of total anthocyanins, DPPH ra

177 HSM also restores superoxide dismutase expression in TGF-beta1-treated lung fibroblas

178 activated catalase and manganese superoxide dismutase expression, indicating that this pathway is co

179 contains exclusively Fe-dependent superoxide dismutases (Fe-SODs).

180 linking of mutations in the Cu,Zn superoxide dismutase gene (sod1) to amyotrophic lateral sclerosis (

181 es and demonstrated that multiple superoxide dismutase genes contribute to miR398b-regulated rice imm

182 1(+)) mouse with the mutant human superoxide dismutase glycine to alanine point mutation at amino aci

183 not antioxidant enzymes (e.g., Mn superoxide dismutase), govern IR survival.

184 gers of superoxide radical anion (superoxide dismutase), hydrogen peroxide (catalase), hydroxyl radic

185 bility of the ALS related protein superoxide dismutase I (SOD1) in mammalian cells, we show that quin

186 substrate (tryparedoxin) and iron superoxide dismutase in COL and SYL (versus TCC) trypomastigotes.

187 OD1) is the principal cytoplasmic superoxide dismutase in humans and plays a major role in redox pote

188 an functionally replace cytosolic superoxide dismutase in yeast, indicating that the pool of Mn displ

189 F-alpha), CXCL10, CCL5, IL-6, and superoxide dismutase, in human macrophages infected with 3 ATCC and

190 t mice with SOD1(G85R) mice, which express a dismutase-inactive mutant of SOD1 and are considered a m

191 tion are similar, suggesting that superoxide dismutase is calibrated so the oxygen- and superoxide-se

192 e-related pine genes such as SOD (superoxide dismutase), LOX (lipoxygenase), PAL (phenylalanine ammon

193 reatment with the small-molecule, superoxide dismutase mimetic (GC4419; 0.25 mumol/L) significantly m

194 Coadministration of tempol, a superoxide dismutase mimetic, ameliorated the exaggerated inflammat

195 because treatment with Tempol, an superoxide dismutase mimetic, rescued kidney injury in knockout mic

196 efficacy and safety of GC4419, a superoxide dismutase mimetic, with placebo to reduce the duration,

197 partially inhibited by Tempol (a superoxide dismutase-mimetic agent) and by glyburide (an inhibitor

198 on of 4-hydroxy-TEMPO (TEMPOL), a superoxide dismutase mimic that reacts with superoxide, rescued the

199 r stress proteins (e.g. manganese superoxide dismutase, mitochondrial KATP channels and peroxisome pr

200 part, by deacetylating manganese superoxide dismutase (MnSOD) and mitochondrial 8-oxoguanine DNA gly

201 Manganese-dependent superoxide dismutase (MnSOD) expression also increased significantl

202 Manganese superoxide dismutase (MnSOD) functions as a tumor suppressor; howev

203 Trx induces manganese superoxide dismutase (MnSOD) gene transcription by activating MKK4

204 Manganese superoxide dismutase (MnSOD) is a mitochondrially localized primary

205 dant enzyme, manganese-containing superoxide dismutase (MnSOD), has dual roles in early- and late-car

206 d decreased activity of manganese superoxide dismutase (MnSOD).

207 e-selective deletion of manganese superoxide dismutase (MnSOD).

208 l antioxidant defenses [manganese superoxide dismutase (MnSOD)P< 0.05; copper/zinc superoxide dismuta

209 Manganese superoxide dismutase (MnSOD/SOD2) is a mitochondria-resident enzyme

210 stable monomeric variant of Cu/Zn superoxide dismutase (mSOD1), an enzyme responsible for the convers

211 and increasing cytoplasmic ROS in superoxide dismutase mutants.

212 ellular antioxidants (sulfhydryl, superoxide dismutase) of zebrafish brain were assessed after recove

213 he proteotoxicity of mutant Cu/Zn superoxide dismutase or C9orf72 dipeptide repeat proteins.

214 anine aminotransferase, catalase, superoxide dismutase, ornithine decarboxylase, glutamate receptor,

215 y high abundance of extracellular superoxide dismutase produced by Synechococcus and a dynamic secret

216 istidine-containing peptides, and superoxide dismutase (SOD) activity have been detected in the raw a

217 ulation, which result from higher superoxide dismutase (SOD) activity, associated with lower catalase

218 g/ml of extract showed revival in superoxide dismutase (SOD) activity.

219 delivery of antioxidant enzymes - superoxide dismutase (SOD) and catalase (CAT), encapsulated in biod

220 f antioxidants (i.e., copper/zinc superoxide dismutase (SOD) and extracellular SOD only in oxidative

221 ioxidants such as catalase (CAT), superoxide dismutase (SOD) and glutathione (GSH).

222 catalase (CAT), peroxidase (POD), superoxide dismutase (SOD) and glutathione reductase (GR) activitie

223 peroxidase (APX), catalase (CAT), superoxide dismutase (SOD) and peroxidase (POD) in roots and shoots

224 ic or mitochondrial ROS scavenger superoxide dismutase (SOD) caused a significant increase in segrega

225 dase (PPO), peroxidase (POX), and superoxide dismutase (SOD) enzymes activities were measured during

226 toma cells the beneficial role of superoxide dismutase (SOD) enzymes against paraquat-induced toxicit

227 n eukaryotes the bimetallic Cu/Zn superoxide dismutase (SOD) enzymes play important roles in the biol

228 The ubiquitous iron/manganese superoxide dismutase (SOD) family exemplifies this deficit, as the

229 ered expression of CSDs and other superoxide dismutase (SOD) family members, leading to increased tot

230 The activity of superoxide dismutase (SOD) in Brassica rapa also displayed a growth

231 Copper/zinc superoxide dismutase (SOD) is a homodimeric metalloenzyme that has

232 Superoxide dismutase (SOD) is a key enzyme that plays a primary rol

233 Superoxide dismutase (SOD) level in the blood samples expressed sig

234 ences in antioxidant capacity and superoxide dismutase (SOD) levels between phenotypes may allow for

235 racellular superoxide by specific superoxide dismutase (SOD) showed the applicability for selective i

236 (glutathione-S-transferase (GST), superoxide dismutase (SOD)), and fish health (condition factor (K),

237 IL10, reduced glutathione (GSH), superoxide dismutase (SOD), and catalase (CAT).

238 ehyde (MDA) and activity of total superoxide dismutase (SOD), and its mitochondrial (Mn-SOD) and cyst

239 Activities of superoxide dismutase (SOD), catalase (CAT) and peroxidase (POD) dec

240 ldehyde (MDA), glutathione (GSH), superoxide dismutase (SOD), catalase (CAT), matrix metalloproteinas

241 reased activities of catalase and superoxide dismutase (SOD), compared to the OS strains.

242 V-A also inhibits the activity of superoxide dismutase (SOD), magnifying the imbalance of redox statu

243 cytokines only when stimulated by superoxide dismutase (SOD)-1.

244 MRI contrast agent and a mimic of superoxide dismutase (SOD).

245 of antioxidant enzymes, including superoxide dismutase (SOD).

246 ant strains lacking mitochondrial superoxide dismutase (sod-2) showed oxidative stress for two FeOx a

247 Copper (Cu)-only superoxide dismutases (SOD) represent a newly characterized class o

248 thione S-transferase P (GSTP) and superoxide dismutases (SOD).

249 The PEF extracts contained 'superoxide dismutase' (SOD), a known food allergen, osmotic shock e

250 BAL superoxide dismutase(SOD), plasma total-antioxidant capacity activi

251 ends on the activity of cytosolic superoxide dismutase, SOD-1.

252 t the activity of the copper/zinc superoxide dismutase Sod1 and that loss of Sod1 activity contribute

253 We previously reported that the dismutase SOD1 is overexpressed in breast cancer.

254 ae) Cu chaperone for Cu-zinc (Zn) superoxide dismutase (SOD1) activates by directly promoting both Cu

255 sis by repressing a Cu-containing superoxide dismutase (SOD1) and inducing Mn-containing SOD3 as a no

256 between homodimeric mutant Cu, Zn superoxide dismutase (SOD1) and wild-type (WT) SOD1 is suspected to

257 1) activates immature copper-zinc superoxide dismutase (Sod1) by delivering copper and facilitating t

258 an inhibit the amyloidogenesis of superoxide dismutase (SOD1) by increasing the intrinsic net negativ

259 lation (nanozyme) for copper/Zinc superoxide dismutase (SOD1) by polyion condensation with a conventi

260 Mutations in superoxide dismutase (SOD1) cause amyotrophic lateral sclerosis (AL

261 Mutations in superoxide dismutase (SOD1) cause amyotrophic lateral sclerosis (AL

262 examine the trajectory that Cu/Zn superoxide dismutase (SOD1) dimers take over the unfolding and diss

263 rences among apo-, Zn-, and Cu,Zn-superoxide dismutase (SOD1) dimers.

264 hout the brain and spinal cord of superoxide dismutase (SOD1) G93A transgenic mice.

265 Mutations in Cu/Zn superoxide dismutase (Sod1) have been reported in both familial and

266 ously, we found that human Cu, Zn-superoxide dismutase (SOD1) is S-acylated (palmitoylated) in vitro

267 Here, we show that Cu, Zn superoxide dismutase (SOD1) is unique among proteins in its ability

268 Cu/Zn superoxide dismutase (SOD1) reduction prolongs survival in SOD1-tra

269 uitous expression of mutant Cu/Zn-superoxide dismutase (SOD1) selectively affects motor neurons in th

270 into the ALS-linked protein Cu,Zn superoxide dismutase (SOD1) upon translation promotes protein misfo

271 Delivery of copper-zinc superoxide dismutase (SOD1), an efficient ROS scavenger, to the sit

272 We focused on Cu-Zn superoxide dismutase (SOD1), which protects cells from oxidative st

273 ed for ALS-linked forms of Cu, Zn superoxide dismutase (SOD1).

274 to the antioxidant metalloenzyme superoxide dismutase (SOD1).

275 in the metallo-enzyme copper-zinc superoxide dismutase (SOD1).

276 ctivated by the UPR(mt), we suggest that the dismutases SOD2 and SOD1 may play key roles in the estab

277 Mitochondrial superoxide dismutase (SOD2) suppresses tumor initiation but promote

278 tivator PGC-1alpha, mitochondrial superoxide dismutase (SOD2), and chemical antioxidants alpha-tocoph

279 upregulation of the antioxidants superoxide dismutase (SOD2), catalase, methionine sulfoxide reducta

280 hyperacetylation of mitochondrial superoxide dismutase (SOD2), increases HIF1alpha (hypoxia-inducible

281 cells by regulating the manganese superoxide dismutase (SOD2).

282 on of ROS-producing extracellular superoxide dismutase (SOD3) in thyroid cancer cell lines although a

283 antioxidant enzyme extracellular superoxide dismutase (SOD3) protects against hypoxia-induced PH.

284 nzymes that detoxify ROS, such as superoxide dismutase (SodA).

285 ine-pyruvate transaminase (avtA), superoxide dismutase (sodB), and 2 hypothetical proteins.

286 eliver the metal ion to the Cu/Zn superoxide dismutase SodCII.

287 stems that include iron-dependent superoxide dismutases (SODs) in mitochondria and glycosomes.

288 The copper-containing superoxide dismutases (SODs) represent a large family of enzymes th

289 Copper-only superoxide dismutases (SODs) represent a new class of SOD enzymes t

290 in catalase, guaiacol peroxidase, superoxide dismutase, soluble protein, lignin, chlorophyll, and ele

291 tems, including a nascent form of superoxide dismutase that is implicated in neurodegenerative diseas

292 organisms employ a separate enzyme, chlorite dismutase, to prevent accumulation of the destructive Cl

293 atalase, ascorbate peroxidase and superoxide dismutase together with xanthophyll cycle and non-photoc

294 Erythrocyte Mn-superoxide dismutase was also reduced at 6 (0.154 vs. 0.096, P = 0.

295 NADP-dependent glyceraldehyde and superoxide dismutase were found significantly upregulated in infect

296 , and mRNA levels of catalase and superoxide dismutase were increased, whereas those of nitric oxide

297 component, biotin carboxylase and superoxide dismutase were related to energy and carbon metabolism,

298 s, and activities of catalase and superoxide dismutase were significantly deteriorated in the CSD gro

299 alase, glutathione peroxidase and superoxide dismutase were significantly lower in PSE-induced sample

300 Among these was the SodA superoxide dismutase, which is essential for mammalian infection.