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1 ia, and the polarity of the basal bodies was disorganized.
2 riched in conditions in which the spindle is disorganized.
3 activity is abrogated, septins are partially disorganized.
4 ry coupling is too weak, spike timing is too disorganized.
5 h levels of PCM are unaffected, it is highly disorganized.
6 re expanded and the extracellular matrix was disorganized.
7 ly absent and those remaining are completely disorganized.
8 ded into 3 domains: psychotic, negative, and disorganized.
9 mited kDNA shrinkage but the networks become disorganized.
10 the pyrenoid of cia6 mutant cells is highly disorganized.
11 egment (OS) lamination, when detectable, was disorganized.
12 at sites of adhesion, although occasionally disorganized.
13 s appear, the HA spikes become conspicuously disorganized, a layer of M1 matrix protein is no longer
14 n early stage in fro mutants, leading to the disorganized accumulation of actin, myosin, and alpha-ac
15 c mice exhibited increased bacterial burden, disorganized accumulation of lymphocytes and mononuclear
16 ngs suggest that DPDG1s and DPDG2s developed disorganized actin cytoskeleton as a consequence of disr
17 ls but decreased cellular F-actin content, a disorganized actin cytoskeleton, impaired chemotaxis, an
22 imilarly, myelination in the spinal cord was disorganized after exposure at 2 dpf but not 1 or 4 dpf.
24 mic axons are delayed, overfasciculated, and disorganized along their pathway through the ventral tel
28 mitosis, sparse cytoplasm, fewer ribosomes, disorganized and clumped organelles, and large vacuoles-
29 , however, the motor pools become temporally disorganized and coupling between independent respirator
30 GP and EP, and disrupted IVD structure with disorganized and decreased GP, EP, and internal AF (IAF)
33 aled abnormal intimal and medial thickening, disorganized and fragmented elastic fibers, reduced smoo
34 llagen is not only increased but also highly disorganized and fragmented within large and small asthm
37 d with controls, Col12a(-/-) osteoblasts are disorganized and less polarized with disrupted cell-cell
41 gen-induced retinopathy model that generates disorganized and poorly perfused neovascular tufts that
43 ed to pattern the new organ, as mutants show disorganized and reduced number of layers and tissue ini
45 stcrossing spinal cord commissural axons are disorganized and showed anterior-posterior guidance erro
46 ow that protrusion and adhesion dynamics are disorganized and that vesicular trafficking to the tip o
47 tions: photoreceptor synapses in the OPL are disorganized and the retinal physiological response is a
48 llagen fibrils in Fam20C-deficient bone were disorganized and thicker while the growth plate cartilag
50 g to their glycoprotein arrays (organized or disorganized) and whether or not they have a resolved M1
52 e, three symptom factors (positive, negative/disorganized, and mood) were identified with exploratory
54 related to helpless/inadequate, overwhelmed/disorganized, and special/overinvolved countertransferen
55 DNA damage and cell death in spermatogonia, disorganized apical ectoplasmic specialization, malforme
56 s may shed light on the circuitry underlying disorganized appetitive responses in psychopathology; e.
57 ging of t-tubules and Ca(2+) showed that the disorganized arrangement of dyads in immature and failin
58 gs and contain smaller ovaries with a highly disorganized arrangement of ovarioles in comparison to w
61 ivity resulted in misaligned neuroblasts and disorganized astrocytes in the RMS/SVZ, linking EphA4 fo
71 find that ric-8a mutation in mice results in disorganized Bergmann glial scaffolding, defective granu
72 lagen IV and pan-laminin were present in the disorganized BM of isolated islets, yet a significant re
76 metanephric mesenchyme leads to ectopic and disorganized branching morphogenesis caused by beta-cate
77 n the proliferation level of salivary cells, disorganized branching morphogenesis, and a lack of diff
79 ctin cytoskeleton (F-actin) in HeLa cells is disorganized by NHERF1, whereas actin protein expression
83 er, the sarcomeres were abnormally small and disorganized, causing skeletal muscle hypoplasia and per
84 e somatic proliferation leading to numerous, disorganized cell layers, suggesting a synergistic inter
86 ation of EC adhesion, as its loss results in disorganized cell-cell junctions and reduced focal adhes
90 conditional knockout mice presented severely disorganized collagen fibers and neovascularization in t
92 alone or in the absence of a scaffold showed disorganized collagen formation and poor tissue healing.
93 Clinical high risk criteria that emphasize disorganized communication and suspiciousness while also
94 idity of 81.8%, consisted of four variables: disorganized communication, suspiciousness, verbal memor
95 isphere was relatively spared, subjects with disorganized community structure had significantly worse
96 maintained fdx5 mutant cells became severely disorganized concomitant with a marked decrease in the r
98 s and complex cognition, and that reduced or disorganized consciousness may be associated with deviat
99 fibrillar fractional-area and sarcomeres are disorganized, contain rod bodies, and have longer thin f
101 erning of the cortical sheet, such as highly disorganized cortical lamination in reeler, led to spect
102 e induced overexpression of NEK6 reduced and disorganized cortical microtubules and suppressed cell e
104 essive elongation of F-actin, resulting in a disorganized cytoskeleton and reduced cell polarity, whi
105 The combined arrested differentiation and disorganized cytoskeleton of PIP5KIgamma-transduced oste
106 els (named as shPAB) were characterized by a disorganized cytoskeleton that lacked polarization.
108 ng with abnormal collagen fibril morphology, disorganized dermal architecture, and reduced skin stren
109 lopment, cortical activity is far from being disorganized, despite the presence of long periods of ne
114 rammed neurons are dissociated and spatially disorganized during transplantation, rendering poor cell
116 ditionally characterized by spatiotemporally disorganized electrical activation and, although initiat
117 res, interictal epileptiform activity with a disorganized electroencephalography background, developm
118 d in Cited2 null embryos is due in part to a disorganized embryonic capillary network, and in part du
119 also observed in Scl(-/-) hearts, where the disorganized endocardium precociously differentiated int
122 phosphorylated cortactin are not detected in disorganized Epha2(-/-) cells with altered F-actin distr
123 skin models was associated with acanthosis, disorganized epidermal architecture, and downregulation
125 e to adequately nourish their pups, due to a disorganized epithelial compartment within their mammary
126 i-1 function in wild-type embryos results in disorganized epithelial migration and occasional morphog
127 RTCB-depleted plasma cells show reduced and disorganized ER structures as well as severe defects in
129 L3 and wing marginal veins and increased and disorganized expression of wingless, the central compone
131 atrix, whereas few myofibroblasts and little disorganized extracellular matrix were noted in eyes tha
132 aracterized by the excessive deposition of a disorganized extracellular matrix, resulting in rigid be
133 yes that had -9.0D PRK, along with prominent disorganized extracellular matrix, whereas few myofibrob
134 the PGC data set; for MGS subjects, negative/disorganized factor scores were correlated with polygeni
135 s based on MGS GWAS results for the negative/disorganized factor were significantly different between
137 cumulate to the midbody, but they are highly disorganized, failing to form symmetric rings and to exp
138 associated with increased interpersonal and disorganized features of schizotypal personality at age
140 hma involves the progressive accumulation of disorganized fibrillar collagen by airway fibroblasts.
141 ssion of CM basement membrane components and disorganized fibrillar collagen matrix, independently of
142 simus resulted in muscle histopathology with disorganized fibrosis that often colocalized with fatty
144 ity to timely destroy CYCA3;4 contributes to disorganized formative divisions, possibly in part cause
146 1 at both metaphase and anaphase, leading to disorganized gamma-tubulin recruitment in centrosomes.
147 of four symptom domains (positive, negative, disorganized, general) and general functioning among cli
148 Bulbs were smaller and presented fewer and disorganized glomeruli and a significant reduction in mi
152 uditory brainstem response, displayed highly disorganized hair-cell stereocilia and had no detectable
153 tic transforming growth factor beta1 (Tgfb1) disorganized hematopoiesis by expanding the pre-EPO pool
154 ng gene expression profiles of polarized and disorganized human mammary epithelial cells in a physiol
155 ed increases in beta-cell VEGF levels led to disorganized, hypervascularized, and fibrotic islets, pr
157 ing of collagen fibrils was found to be more disorganized in asthmatic airways compared with control
160 ial CXL; similarly, collagen fibers appeared disorganized in keratoconus, while their pattern appears
162 s were disorganized in VAD mice and were not disorganized in Rpe65(-)/(-) mice, although they were sh
163 icroscopy revealed fiber membranes that were disorganized in the lenses of VIM(SA/SA), reminiscent of
166 at the outer segments of photoreceptors were disorganized in VAD mice and were not disorganized in Rp
167 Although hindbrain floor plate cilia are disorganized in vangl2 mutant embryos, cilia appear to b
168 e defect in the hippocampus, a shortened and disorganized infrapyramidal bundle of the mossy fiber pr
174 is of angle structures, and a hypoplastic or disorganized iris were also observed in the 3 cases.
176 This phenotype was accompanied by a highly disorganized lamellar actin network and rescued by the a
177 layer and the basement membrane, leading to disorganized lamination and an absence of cerebellar fol
179 65/FE65L1 double knockout (DKO) mice display disorganized laminin in meningeal fibroblasts and a cobb
180 2-knockout models had a small forebrain with disorganized layering of neurons and nuclear shape abnor
181 rmation explains how EphA2 mutations lead to disorganized lens cells that subsequently contribute to
182 in shortened body axis, microphthalmia with disorganized lens, microcephaly, reduced touch-evoked mo
183 inhibition of AM signaling revealed markedly disorganized lymphatic junctional proteins ZO-1 and VE-c
184 rozygous female mice are fertile but contain disorganized mammary epithelial cells, in which zonal oc
186 bryos lacking Tal1, endocardial cells form a disorganized mass within the ventricle and do not popula
187 tors fails to differentiate and develop into disorganized masses resembling acinar to ductal metaplas
189 iates from triggers by organized rather than disorganized mechanisms, either via spiral wave re-entry
190 ved mouse embryonic fibroblasts have visibly disorganized membranes, unprocessed internal vesicles an
191 ilencing of Sox102F led to misorientated and disorganized michrochaetes, neurons with shorter dendrit
192 tissues by identifying the heterogeneous and disorganized microscopic tissue structures indicative of
193 sent during clot formation produce a visibly disorganized microstructure that increases clot stiffnes
195 on outgrowth and growth cone turning, due to disorganized microtubules that fail to enter filopodia a
196 protein (GFP)-tubb6 (but not GFP-tubb5) have disorganized microtubules whereas mdx muscle fibers depl
199 scopy (TEM) revealed myofibril degeneration, disorganized mitochondrial cristae, lipid inclusions and
200 is revealed that Parkin-deficient hearts had disorganized mitochondrial networks and significantly sm
201 proteins, which is sufficient to bring about disorganized mitochondrial networks, reduced aerobic res
202 ence during cell division is associated with disorganized mitotic chromosome movements and chromosome
209 ne turning in Wnt5a gradients, likely due to disorganized MTs that failed to extend into the peripher
215 MGRKO and GR(-/-) mice at E17.5, with short, disorganized myofibrils and cardiomyocytes that fail to
217 into the developing eyefield in vivo, led to disorganized nerve ring formation and premature cornea i
218 esponse to simple 40-Hz stimulation reflects disorganized network function in schizophrenia patients.
221 BS mutation in yeast (eco1-W216G) exhibits a disorganized nucleolus and reduced looping at the rDNA.
223 elopment based on a rough-eye phenotype with disorganized ommatidia observed in adult escapers of the
224 uffices in predicting the self-organized and disorganized orientation maps from primates to rodents.
225 tology and electron microscopy (EM) revealed disorganized OS as early as 3 weeks with complete loss b
226 0 in type I collagen-positive cells led to a disorganized outer AF (OAF) with thinner, loosened, and
227 cific reduction in outer rod segment length, disorganized outer rod segment discs, and mislocalizatio
228 aggregate formation during stage 9 (S9), and disorganized parallel actin filament bundles during stag
231 wing that cystogenesis was associated with a disorganized pericystic network of vessels expressing pl
236 atient with renal disease have elongated and disorganized primary cilia and that this ciliary phenoty
239 Furthermore, PSCs from both muscles extended disorganized processes from denervated NMJs and failed t
240 s and proximal axons of spinal cord neurons, disorganized processes in the cerebellum and abnormal pr
242 ifferent stages of macroautophagy, including disorganized protein aggregations (sequestosomes), seque
245 nvasively correlates well with organized and disorganized regions detected by panoramic intracardiac
248 s, as cells expressing SpAin1(R216E) display disorganized ring material and delays in both ring forma
249 ype of cc2d2a mutant zebrafish consisting of disorganized rod and cone photoreceptor outer segments r
251 bited early-onset retinal degeneration, with disorganized ROS structures, autofluorescent deposits in
252 eatures of CM dedifferentiation, including a disorganized sarcomere network, rounding, and conspicuou
255 tbd5 null mice have smaller muscle fibers, a disorganized sarcomeric structure, increased extracellul
257 initially classified as having catatonic or disorganized schizophrenia were reclassified as having m
258 rior cingulate cortex and precuneus (and for disorganized schizotypy, also in medial prefrontal corte
259 brain was significantly widened and appeared disorganized, showing aberrant posterior-directed growth
260 ls, we observed an increase in the number of disorganized spindle microtubules owing to multipolar co
262 levels, accelerated migration, invasion, and disorganized sprout formation in response to elevated IL
267 n addition, cytoplasmic actin filaments were disorganized, suggesting links between the nuclear lamin
268 t related to genetic effects on negative and disorganized symptoms (i.e., core features of chronic sc
269 5; 95% CI, 1.258-2.732; P = .002), and total disorganized symptoms (OR, 5.06; 95% CI, 1.548-16.527; P
270 s displayed an aberrant mitotic spindle with disorganized, tangle-shaped microtubules and reduced ast
271 -shaped t-tubule vesicles, as well as highly disorganized terminal cisternae of sarcoplasmic reticulu
273 ed the expression of tight junction markers, disorganized the cell-cell junction, and increased perme
274 th the function of E-cadherin in macrophages disorganized the granulomas and protected the fish, intr
275 tubules; in their absence, microtubules were disorganized, the axonal kinesin UNC-104 invaded dendrit
276 inattention (36%), disorientation (27%), and disorganized thinking (18%) were also common but were of
278 thunderstorms, with decreasing deposition in disorganized thunderstorms, quasi-linear convective syst
279 ssion, as cessation of 4HT treatment induced disorganized tissue architecture and p21-associated diff
281 rom simple epithelial structures to complex, disorganized tissues with large cellular diversity.
283 ons, we show that patient tumour vessels are disorganized, tortuous and approximately 50% do not supp
284 s does not prevent secretion, but results in disorganized trafficking and fusion between secretory ve
285 son's symptoms by capturing the increasingly disorganized transitions between syllables as motor impa
286 w shear stress due to poor blood flow in the disorganized tumor vasculature induces expression of CLE
288 heterozygous for the human allele displayed disorganized ultrastructural properties of the aortic wa
289 We infer from these results that irregular, disorganized variations in matrix mechanics, compared wi
290 These findings contrast sharply with the disorganized vasculature elicited by induction of vascul
291 however, loss of epsins 1 and 2 resulted in disorganized vasculature, significantly increased vascul
294 adins structure appeared to be progressively disorganized with the temperature increase up to 100 deg
296 optic nerve and the posterior commissure are disorganized, with the optic nerve failing to reach its
298 rgery), having no or few myelin layers, were disorganized within a fibroblast-rich collagenous scar.
299 aming and nemaline-like bodies adjacent to a disorganized Z-line on electron microscopy, recapitulati
300 reased the accessibility of enzymes to these disorganized zones, resulting in a delayed onset of degr