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1 sting resource use for these patients is not disproportionate.
2 o identify products or practices that have a disproportionate adverse impact on the environment and m
3 from high-emission-generating sources bear a disproportionate air-pollution burden.
4   Cardiovascular risk factors are common and disproportionate among disadvantaged populations in Sout
5 ent spending is both insufficient and highly disproportionate among groups of species, and there is s
6  as Sparc Finally, the transcripts contain a disproportionate amount of a binding motif for the quaki
7 studied as this subset of patients consume a disproportionate amount of healthcare services compared
8 with the highest forecast errors and cause a disproportionate amount of human and financial losses.
9 ing the Drosophila olfactory system harbor a disproportionate amount of interspecies variation.
10 apillary length in cortex, indicating that a disproportionate amount of leakage occurred from a small
11 ntracerebral hemorrhage (ICH) accounts for a disproportionate amount of stroke-related morbidity and
12 among outdoor worker populations who spend a disproportionate amount of time working outdoors.
13 at dopamine increases energy metabolism by a disproportionate amount relative to the CBF response, ca
14          Individuals with COPD use large and disproportionate amounts of health services.
15                                 They consume disproportionate amounts of healthcare resource.
16 se, whereas sporadic Alzheimer's disease had disproportionate amyloid-beta(4)(2) accumulation in cort
17                   These results suggest that disproportionate amyloid-beta(4)(2) accumulation in cort
18 served that familial Alzheimer's disease had disproportionate amyloid-beta(4)(2) accumulation in subc
19 y be mediated by synaptic processes, whereas disproportionate amyloid-beta(4)(2) accumulation in subc
20 ers are changing ecosystems globally, with a disproportionate and intensifying impact on freshwater h
21 ophy (red flag features: orofacial dystonia, disproportionate antecollis, camptocormia and/or Pisa sy
22              Instead, Mn(III) is proposed to disproportionate at an adjacent polynuclear site, thereb
23 -ABC(DKO) BM-transplanted Ldlr(-/-) mice had disproportionate atherosclerosis, considering they also
24 al journalists and editors should adjust the disproportionate attention given to contrarians.
25  Epidemic readiness and response command the disproportionate attention of health security decision m
26 ulfate and thiosulfate reducers, thiosulfate-disproportionating bacteria, and remarkably sulfur-oxidi
27 tween drugs and adverse drug reactions using disproportionate Bayesian-reporting; IC(025) (lower end
28 distinct GABA(A) receptor subtypes will have disproportionate benefits over adverse effects.
29 s and organs affected were not significantly disproportionate between the study groups.
30                                 Islands hold disproportionate biodiversity, and are subject to accele
31  changes in environmental conditions trigger disproportionate biotic responses.
32 onduction defects in these tissues produce a disproportionate burden of arrhythmic disease and are ma
33             African Americans (AAs) suffer a disproportionate burden of colorectal cancer.
34 rgency general surgery (EGS) patients have a disproportionate burden of death and complications.
35 th system interventions may help address the disproportionate burden of diabetes in low- and middle-i
36  with chronic kidney disease (CKD) exhibit a disproportionate burden of elevated blood pressure (BP)
37                         India accounts for a disproportionate burden of global childhood illnesses.
38                          In hospitals with a disproportionate burden of HAIs, access to tools to assi
39                          In hospitals with a disproportionate burden of health care-associated infect
40                                 Worldwide, a disproportionate burden of HIV, tuberculosis, and hepati
41  that men (MSM) who have sex with men bear a disproportionate burden of HIV.
42           School-aged children (SAC) carry a disproportionate burden of infections, suggesting either
43 hat the world's poorest people may take on a disproportionate burden of noncommunicable diseases, eve
44                Puerto Rican children share a disproportionate burden of prematurity and asthma in the
45   A small number of procedures account for a disproportionate burden of revisit-associated resource u
46 nority group in the United States and face a disproportionate burden of risk factors for cardiovascul
47 munities around the world are experiencing a disproportionate burden of severe acute respiratory synd
48 pulation with increasing comorbidities and a disproportionate burden of social problems.
49         Local ancestry may contribute to the disproportionate burden of subclinical and clinical card
50 sub-Saharan Africa and evidence suggesting a disproportionate burden of these diseases among detainee
51 e differences in insulin sensitivity and the disproportionate burden of type 2 diabetes in African Am
52 ng sex differences in PTSD incidence and its disproportionate burden on society, there is a dearth of
53                                U(V) does not disproportionate but stabilizes on magnetite through pre
54                  Many hs-{FeNO}(8) complexes disproportionate by forming dinitrosyl iron complexes (D
55                               Because of the disproportionate canagliflozin exposure in the database,
56                                      Certain disproportionate changes in global E/I trigger network o
57 reserves until minor stressor events trigger disproportionate changes in health status.
58 ievement may be undermined by increasing and disproportionate chronic disease burden among PLHIV.
59 l regions and connections that contribute to disproportionate communication flow, (b) integrate globa
60 vironmental parameters can have dramatic and disproportionate consequences on population viability.
61 rate production and allocation, suggesting a disproportionate contraction of the belowground ecosyste
62 tly offset NEP during the wet season, with a disproportionate contribution by single major monsoonal
63 ting bias, and sensitivity analyses showed a disproportionate contribution from critical illness poly
64 clude studies with a high risk of bias and a disproportionate contribution from studies examining pat
65 scale, a lack of common identifiers, and the disproportionate contribution of a platform to the 'batc
66 ositively depend on the presence, abundance, disproportionate contribution or, counterintuitively, th
67 r results indicate that rare variants make a disproportionate contribution to genetic risk for prosta
68 efficients show that large herbivores make a disproportionate contribution to lateral nutrient transf
69 t isolates to show that rare variants make a disproportionate contribution to trait variation.
70  mutations or certain types of mutation make disproportionate contributions to adaptive phenotypic ev
71             The factors driving the observed disproportionate CTD-associated ASCVD in African America
72 ven primarily by mortality events (i.e., the disproportionate death of highland vs. lowland species),
73 al evidence that climate change will cause a disproportionate decline in African antelopes with small
74 -depth analysis of one gene, DAAM2, showed a disproportionate decrease in bone strength relative to m
75            The reduction in overall size and disproportionate decrease in third molar size have been
76 in testis and thymus, Ube2w KO mice showed a disproportionate decrease in weight of these two organs
77 targeted vaccination primarily reflected the disproportionate demographic burden of TB among the popu
78 omic makeup with sulfate-reducing and sulfur-disproportionating Desulfobulbaceae, with few core genes
79          Patients with surface dyslexia have disproportionate difficulty pronouncing irregularly spel
80 th racial and ethnic minorities experiencing disproportionate disease burden.
81  findings offer insights on the mechanism of disproportionate disease susceptibility in men and ident
82  charge at the exposed surface of GTO charge disproportionates due to correlation effect making the s
83 Npr2 named peewee (pwe) that exhibits severe disproportionate dwarfism and female infertility.
84                                    Given the disproportionate ecological impacts of large-bodied herb
85 ounger than 5 years of age worldwide, with a disproportionate effect in sub-Saharan Africa.
86  Our results suggest long-term cooling had a disproportionate effect on non-tropical diversification
87 hich-relative to its low concentration-has a disproportionate effect on the solidus that has not been
88 nited States and Europe have highlighted the disproportionate effects of COVID-19 on patients with ca
89 no-seeds-added controls, with exotics having disproportionate effects on productivity compared with n
90                     Elevated pCO(2) also had disproportionate effects on the abundance of sequences r
91 ic inflammation alters behavior and produces disproportionate effects, such as delirium, in vulnerabl
92 cialization, overreliance on reductionism, a disproportionate emphasis on scientific outputs, and oth
93 ocalization into nuclear speckles leads to a disproportionate enhancement of mRNA splicing and a redu
94 with pronounced effects at genes featuring a disproportionate ENL load.
95 ised therapy in 20 elementary schools with a disproportionate enrollment of low-income Latino student
96                                  Trade has a disproportionate environmental impact, while the interna
97 ltotriose, which would otherwise accumulate, disproportionating enzyme 1 (DPE1; a 4-alpha-glucanotran
98 tosolic transglucosidase (also designated as disproportionating enzyme 2, DPE2) or the maltose transp
99  mutants lacking both PHS1 and the cytosolic DISPROPORTIONATING ENZYME2 (DPE2) displayed only one sta
100 experimental cognitive neuroscience revealed disproportionate episodic memory impairments in schizoph
101  years with advanced-stage cHL experienced a disproportionate excess of deaths as a result of heart d
102 s a form of dosage compensation to cope with disproportionate expression of protein complex subunits.
103                                          The disproportionate failure of regenerating tubules to redi
104 atively, tissue layers can develop to bear a disproportionate fiber tension (i.e., a ligament with hi
105 er striatal dopamine depletion stem from the disproportionate firing rates of spiny projection neuron
106          The medical community's traditional disproportionate focus on treating cardiovascular diseas
107               In particular, we found that a disproportionate fraction of lipid variation in African
108                    Young women account for a disproportionate fraction of new HIV infections in Afric
109 hough relatively common SNPs accounted for a disproportionate fraction of risk.
110       Rare cancers collectively contribute a disproportionate fraction of the total burden of cancer.
111  the plant taxa that can potentially lead to disproportionate gains in biodiversity.
112 s of the maternal allele of Igf2r results in disproportionate growth and peri-natal lethality.
113                             Developmentally, disproportionate growth can arise through trait-specific
114 uents (R=H, Me), the complexes catalytically disproportionate H2O2 in aqueous solution; with a bulky
115 s that patients with low genetic risk suffer disproportionate harm when treated with rFVIII (risk inc
116                 Sepsis is characterized by a disproportionate host response to infection that often c
117 as contributed to cerebral expansion and the disproportionate human brain size, consistent with the s
118 r phospholipidosis, the risk of formation of disproportionate human metabolites, and the risk of form
119 G's) are bifunctional heme proteins that can disproportionate hydrogen peroxide (catalatic reaction)
120 alase enzymes, it exhibits a low activity to disproportionate hydrogen peroxide (H2O2).
121 ce of HIV infection, L. monocytogenes caused disproportionate illness among pregnant girls and women
122  or whether each non-native individual has a disproportionate impact - that is, a higher per-capita e
123 n this article we will describe the emerging disproportionate impact of COVID-19 on the Hispanic/Lati
124 omotion of large trees and animals will have disproportionate impact on biodiversity, ecosystem proce
125 Our results suggest that small drains have a disproportionate impact on enclosed beach water quality
126  slower prefrontal and temporal areas have a disproportionate impact on global brain dynamics.
127 ources in the Southern Hemisphere could have disproportionate impact on ocean productivity.
128 nt Staphylococcus aureus (CA-MRSA) has had a disproportionate impact on patients with human immunodef
129 gate damage by 'rogues' (individuals causing disproportionate impact) or to target 'recalcitrants' (i
130 nt, with small numbers of individuals having disproportionate impact.
131 t of functionally important species having a disproportionate impact.
132 al buyers and specific hot spots explain the disproportionate impacts of some actors on endemic speci
133 portance of reducing emissions to avoid such disproportionate impacts on ecosystems and people.
134              In germ cells, Piwi loss showed disproportionate impacts on steady-state RNA levels, ind
135          These findings may help explain the disproportionate impairment evident in more effortful co
136 s and treat in patients with asthma who have disproportionate impairment of small airway function.
137 mangroves and their organic sediments are of disproportionate importance to global carbon sequestrati
138 ent situations, but fear learning can become disproportionate in vulnerable individuals.
139                 Sm(II){Co(CO)3(PCy3)}2(THF)3 disproportionates in pentane to form Sm(III){Co(CO)3(PCy
140 h as well as microcephaly (i.e., overall and disproportionate) in the offspring of women attending a
141 workers through the Affordable Care Act; (3) disproportionate incarceration of BIPOC into crowded pri
142                                  Despite the disproportionate incidence of Covid-19 among underserved
143 Low-income and minority mothers experience a disproportionate incidence of depression and lack access
144                          Observations of the disproportionate incidence of depression in women compar
145 itals; however, in 2007 to 2012, there was a disproportionate increase at hospitals with large bedsiz
146 tin during oligomerization in vitro led to a disproportionate increase in 18mers.
147 cardial infarction and is characterized by a disproportionate increase in filling pressure during exe
148  increase in indel frequency, resulting in a disproportionate increase in indels (vs.
149 aution because this may be associated with a disproportionate increase in insulin as judged by an inc
150  overexpression of PMP22 in CMT1A leads to a disproportionate increase in misfolding and mistrafficki
151 corporation of fluorine is associated with a disproportionate increase in MW considering the van der
152 chopathology have triggered concerns about a disproportionate increase in the treatment of youths wit
153 n have increased over the past decade with a disproportionate increase in young and middle-aged adult
154 ealthy subjects, although we did not observe disproportionate increases in 12alpha-hydroxylated BAs.
155 by releasing the native from competition via disproportionate increases in herbivory on the invader.
156 reductions in application rate outweighed by disproportionate increases in potency (toxicity/kg) and
157 increased weight is supported solely through disproportionate increases in wing area.
158 e detection rates of DCIS were not driven by disproportionate increments of the slowly progressive lo
159 ral gas supply chain requires addressing the disproportionate influence of high-emitting sources.
160  find that the most dominant species exert a disproportionate influence on functioning at low levels
161            Freshwater lakes, in turn, have a disproportionate influence on global carbon and nitrogen
162 particular individuals, leaders, that have a disproportionate influence on group decision-making.
163 ory suggests that living root inputs exert a disproportionate influence on SOC formation, but few fie
164                 Because "megamammals" have a disproportionate influence on vegetation, trophic intera
165        Atypically long infections may have a disproportionate influence upon global patterns of viral
166 loss of the interstitial buffer capacity and disproportionate interstitial fluid accumulation.
167  initially produces LiO2, which subsequently disproportionates into Li2O2 and O2.
168 nemy civilians (in survey 1) or approving of disproportionate killing with conventional weapons (in s
169  direct deaths of women and children and had disproportionate lethal effects on civilians, calling in
170        Conformist transmission, defined as a disproportionate likelihood to copy the majority, is con
171                            Thus, halting the disproportionate loss of ecological strategies associate
172  species and lineages, possibly leading to a disproportionate loss of existing evolutionary history (
173                             No evidence of a disproportionate loss of high-metabolic rate organs (hea
174 ident HF in older adults was associated with disproportionate loss of lean mass, particularly among m
175 election pressure on these FBTs, causing the disproportionate loss of one group.
176                             The PT group had disproportionate loss to follow-up.
177 ith ASD, cerebral overgrowth in the ASD with disproportionate megalencephaly subgroup was predominate
178       For example, autistic individuals with disproportionate megalencephaly, a subgroup with higher
179 ic and healthy control participants revealed disproportionate memory deficits in schizophrenia for re
180           Despite the clinical importance of disproportionate memory for negative compared with posit
181 eloping HF, loss of total lean body mass was disproportionate; men with HF lost 654.6 versus 391.4 g/
182 I 1.2-22.5) and a ten-fold increased risk of disproportionate microcephaly (RR 10.3, 95% CI 2.0-52.6)
183 se patients, designated as having severe but disproportionate MR, respond favorably to treatments tha
184 plex electron transfer (ET) within a "charge-disproportionated" myoglobin (Mb) dimer with greatly enh
185 t the ferrous ions in Fe(2+)-exchanged MOF-5 disproportionate nitric oxide to produce nitrous oxide a
186   The function of this allele, and that of a disproportionate number of autoimmune disease risk allel
187 eting, a mere 8 institutions accounted for a disproportionate number of both oral concurrent sessions
188                             In conclusion, a disproportionate number of Caryophyllales species behave
189                                   However, a disproportionate number of cases clustered around 1 prov
190 ome; a small group of drugs contributed to a disproportionate number of cases, and causality with Rou
191 des, and these connections participated in a disproportionate number of communication paths linking n
192 small number of ophthalmologists generated a disproportionate number of complaints.
193 l receptor-targeted treatments, leading to a disproportionate number of deaths.
194 s studies still result in the detection of a disproportionate number of features that cannot be confi
195                                            A disproportionate number of genes coding for proteins inv
196                                            A disproportionate number of germ cell divisions were obse
197                                            A disproportionate number of impoverished and minority chi
198                 Safety-net hospitals treat a disproportionate number of patients with advanced append
199 ly, we find multiple journals that publish a disproportionate number of preprints from some countries
200 ted in only 1-2 bands; within these bands, a disproportionate number of RNAPs were found in clusters
201 nfections across North America, identified a disproportionate number of SNPs in the gene encoding mul
202 mal and bird species, and reptiles include a disproportionate number of species with insufficient ext
203 ignated as "cheaters" because they produce a disproportionate number of spores in chimeric fruiting b
204  to stature in human genetic studies, with a disproportionate number of these loci also shown to be u
205 aliBase benchmark, namely the inclusion of a disproportionate number of transfer RNAs, which exhibit
206  for C1 metabolism in many microorganisms, a disproportionate number of which are opportunistic human
207  mammals, the rodents, which also comprise a disproportionate number of zoonotic disease reservoirs.
208                                 There was no disproportionate occurrence of known RA, CD, UC, or T1D
209 prescription and understanding mechanisms of disproportionate opioid-related adverse effects in Afric
210               While hydroxylamines typically disproportionate or decompose in the presence of transit
211 ynthetic, compounds that are responsible for disproportionate percentages of hits but are false activ
212 ls previously infected with influenza have a disproportionate probability of being highly connected w
213                         Through the input of disproportionate quantities of chemically distinct litte
214 hat differ in "catalytic bias" by exerting a disproportionate rate acceleration in one direction or t
215 he United States (US) are affected by HIV at disproportionate rates compared to MSM of other race/eth
216                              To rectify this disproportionate ratio, we demonstrate a simple, yet pow
217       Our findings suggest that an early and disproportionate reduction in osmotic conductance during
218 upernumerary X- and Y-chromosomes both cause disproportionate reductions in PV, and coordinated defor
219                    We noted no indication of disproportionate reporting of adverse events after immun
220 cal Bayesian data mining methods to identify disproportionate reporting of adverse events for IPV com
221  proarrhythmic drug) and was associated with disproportionate reporting similar to that of antiarrhyt
222  of mortality and morbidity because of their disproportionate representation among COVID-19 hospitali
223 n intensities, becomes irrelevant due to the disproportionate response factors of the homologues.
224                        We concluded that the disproportionate retesting of some compounds represents
225            African American individuals have disproportionate risk factors (diabetes, hypertension) p
226 nsgender women who engage in sex work have a disproportionate risk for HIV compared with natal male a
227 m disorder (ASD), while the deletion confers disproportionate risk for schizophrenia.
228 ancy does not seem to increase their already disproportionate risk of cognitive delay.
229 are known cardiovascular toxicants that pose disproportionate risk to rural communities where environ
230 ransgender people who sell sex globally have disproportionate risks and burdens of HIV in countries o
231 aryotes, structural mutations may have had a disproportionate role during adaptive divergence and spe
232  by involvement of sex chromosomes playing a disproportionate role in reproductive isolation.
233 an any other biome on Earth, and thus play a disproportionate role in the global climate.
234 that warm semi-arid ecosystems are playing a disproportionate role in the interannual variability and
235 that warm semi-arid ecosystems are playing a disproportionate role in the interannual variability and
236 redicts that X (or Z) chromosomes could play disproportionate roles in speciation and evolutionary di
237 e seen the consolidation of influence in the disproportionate roles the USA, UK, and the Bill & Melin
238 uding sulphur oxygenase reductase (SOR) that disproportionates S degrees into H(2) S and sulphite (SO
239  lead to weight gain, instead of the current disproportionate scientific interest in the biological p
240 ing NO(3)(-) (18)O/(16)O ratios showed (1) a disproportionate sensitivity to the (18)O/(16)O ratio of
241 unt for graduate medical education payments, disproportionate share costs, and regional wage-index ad
242 as being in the top quartile of the Medicare disproportionate share hospital (DSH) patient percentage
243                                      Federal Disproportionate Share Hospital (DSH) payments help hosp
244      Similar patterns were observed for high disproportionate share hospital (OR [95% CI]: 1.44 [1.42
245 rences, -37 [95% CI, -224 to 150]; P = .70), Disproportionate Share Hospital Index (1.7% vs 0.4%; dif
246 ences in socioeconomic status and receipt of disproportionate share hospital payments (a marker of sa
247                                              Disproportionate Share Hospital payments to FSCHs reduce
248 or air quality is unevenly distributed and a disproportionate share is located in low-income, non-whi
249 e highest decile of spending accounted for a disproportionate share of aggregate costs: 30% in Colect
250 from ethnic minorities in England reported a disproportionate share of cervical disease.
251  covered by Medicaid or uninsured, provide a disproportionate share of medical care to vulnerable pop
252 f all breast cancer but is responsible for a disproportionate share of morbidity and mortality becaus
253 me high-mileage fleets are responsible for a disproportionate share of the fleet's emissions.
254 thesized that such eQTLs might account for a disproportionate share of the heritability estimated fro
255 that low- and middle-income countries have a disproportionate share of these disorders, and that many
256 f multimorbid patients was responsible for a disproportionate share of total Medicare spending, but t
257 : a small population segment accounted for a disproportionate share of use-events and costs across mu
258 ences for safety-net institutions caring for disproportionate shares of Medicaid or uninsured patient
259 bits endochondral ossification, resulting in disproportionate short stature and clinically significan
260 , pain, poor mineralization of the teeth and disproportionate short stature in children as well as hy
261 ed nasal bridge, metaphyseal striations, and disproportionate short stature.
262  ACH patients, including growth retardation, disproportionate shortening of the limbs, round head, mi
263 idence of a COL4A1 functional subdomain with disproportionate significance for tissue-specific pathol
264                                            A disproportionate stemness load, caused by integrated tra
265                                 Aging causes disproportionate stiffening of the aorta compared with t
266 ver, genetic elimination of NB2 results in a disproportionate stripping of inhibitory boutons from hi
267 ymmetries to settle contests, leading to the disproportionate success of the initial resident 'owner'
268 te these abnormalities, C. albicans SOD5 can disproportionate superoxide at rates limited only by dif
269 uctural deviations, SOD5 has the capacity to disproportionate superoxide with kinetics that approach
270 the metabolism of reactive oxygen species by disproportionating superoxide anion radical to oxygen an
271 in the biology of reactive oxygen species by disproportionating superoxide anion.
272 e burden, with cancer and HIV/AIDS receiving disproportionate support.
273 ual compounds were tested (1-1613 times) and disproportionate testing of some compounds.
274 itional breeding techniques; (ii) it is risk-disproportionate to apply metabolomics for regulatory pu
275 aking their role in the global carbon budget disproportionate to land area.
276                           Exertional dyspnea disproportionate to pulmonary function tests, low carbon
277 enerates labile Mn(III) cations that rapidly disproportionate to reform aqueous Mn(II) and solid-phas
278 (IV) produces transient Mn(III) species that disproportionate to regenerate aqueous Mn(II) and struct
279 roval has become increasingly burdensome and disproportionate to the conceivable risks to research pa
280 IH's allocation of research funding is often disproportionate to the current health needs of the Amer
281 of provisions that impede access to opioids, disproportionate to their (intended) benefit in preventi
282 thesis that patients with vision-related QOL disproportionate to their 24-2 VF status may exhibit 10-
283 of these have investigated diatoms, which is disproportionate to their contribution to global primary
284  autoimmune cholestatic liver diseases, that disproportionate to their incidence and prevalence, rema
285 (T cell and neutralising antibody) responses disproportionate to their replication.
286                 A(H7N9) disease incidence is disproportionate to viral exposure, suggesting that host
287  perovskite is unstable; it loses its Fe and disproportionates to a nearly Fe-free MgSiO3 perovskite
288 o form a pentavalent U(V) intermediate which disproportionates to form U(VI) and U(IV).
289 is weakly protonated to give HTCNQ(*), which disproportionates to TCNQ and H(2)TCNQ.
290 to give "[(bpy)Cu(CF3)2]" that spontaneously disproportionates to two Cu(III) ([Cu(CF3)4](-) and [(bp
291 plex 2 is thermally unstable and loses N(2), disproportionating to Fe nanoparticles among other produ
292 sease 2019 (COVID-19) pandemic is exacting a disproportionate toll on ethnic minority communities and
293                  These findings suggest that disproportionate undergrowth of a task-control system (F
294 fuel growth and proliferation, including the disproportionate use of glucose, glutamine, and fatty ac
295 he endogenous opioid system may underlie the disproportionate use of opioids among patients with mood
296 ts with functional mitral regurgitation (eg, disproportionate versus proportionate mitral regurgitati
297 , where compulsive actions are recognized as disproportionate, we hypothesized that action and confid
298 ell-known observation that predictors assign disproportionate weight to conservation, as well as the
299 nce unfolds over time, humans tend to assign disproportionate weight to the later part of the experie
300 rimental conditions, I2(*-) in CH3CN rapidly disproportionates with a tremendous loss of free energy,

 
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