ライフサイエンスコーパス: distal dendrite

1 rgeting can occur from both the proximal and distal dendrite.

2 input through specialized synapses on their distal dendrites.

3 in addition to spines, targeted proximal and distal dendrites.

4 nal axonal output, most of its output is via distal dendrites.

5 nd acidic microdomains, which predominate in distal dendrites.

6 enuated at the soma for stimulation sites on distal dendrites.

7 es, and was present also in smaller diameter distal dendrites.

8 ion potentials often fail to invade the most distal dendrites.

9 plasma membrane-bound channels is greater in distal dendrites.

10 s are present within dendritic spines and in distal dendrites.

11 g, truncated TrkB promoted net elongation of distal dendrites.

12 ortical inputs onto CA2 compared with CA1 PN distal dendrites.

13 al circuit neurons and targeted mainly their distal dendrites.

14 re observed on the soma and the proximal and distal dendrites.

15 of contacts (<1/100 microm2) on proximal and distal dendrites.

16 ude of back-propagating action potentials in distal dendrites.

17 nts (Ih) increased over sixfold from soma to distal dendrites.

18 itude of fast spikes varied substantially in distal dendrites.

19 triking, claw-like appearance to many of the distal dendrites.

20 nge is hyperpolarized relatively more in the distal dendrites.

21 proximal dendrites and excitatory inputs on distal dendrites.

22 primary, 2.5:1.2 on secondary, and 0.8:12 on distal dendrites.

23 and only 7% established synaptic contacts on distal dendrites.

24 of labeled cortical boutons, mainly targeted distal dendrites.

25 with decreased beta-spectrin localization in distal dendrites.

26 but only the alpha form was observed in more distal dendrites.

27 was distributed over proximal and sometimes distal dendrites.

28 model assuming higher densities of I(Ts) in distal dendrites.

29 of the visual field onto compartmentalized, distal dendrites.

30 powerful inhibition of CA1 pyramidal neuron distal dendrites.

31 nd backpropagation of action potentials into distal dendrites.

32 ly sustained compared to those measured from distal dendrites.

33 ade exclusively over long distances and onto distal dendrites.

34 and was present throughout the proximal and distal dendrites.

35 y tight electrotonic coupling of the soma to distal dendrites.

36 ns: Kv2.1 in proximal dendrites and Kv4.2 in distal dendrites.

37 gnificant decrease in total spine density in distal dendrites.

38 d with a particular focus on proximal versus distal dendrites.

39 in ventral versus dorsal CA1 pyramidal cell distal dendrites.

40 ion of spines by cocaine on proximal but not distal dendrites.

41 Delta[Ca2+] decreases significantly in more distal dendrites.

42 e they contacted small spines located in the distal dendrites.

43 decrease in A-type current, specifically in distal dendrites.

44 ) current and increased the bAP amplitude in distal dendrites.

45 n for synaptic integration and plasticity in distal dendrites.

46 cialized dendrodendritic synapses located on distal dendrites.

47 ng more than 3-fold between the soma and the distal dendrites.

48 neurons, but they often fail to fully invade distal dendrites.

49 fold attenuation for synapses on many small, distal dendrites.

50 found on the somata, proximal dendrites, and distal dendrites.

51 e asymmetrical synapses on small, presumably distal, dendrites.

52 bserved, mostly involving secondary and more distal dendrites (0.5-1.0 microm thick).

53 The remaining terminals formed synapses with distal dendrites (23-28%) and spines (8-12%).

54 On distal dendrites, 60-65% were ST, 20% were LT, and 15% w

55 All cell types made synapses on distal dendrites; a proportion of the fast-spiking and b

56 omatic Kv7 channel block backpropagated into distal dendrites affecting their activity, despite these

57 mas, and, unlike other Kv3 proteins, also in distal dendrites, although precise subcellular localizat

58 ovide a direct signaling pathway between the distal dendrite and the nucleus resulting in modulation

59 unctions were present at a higher density on distal dendrites and contributed substantially to membra

60 hout pyramidal cell somata and extended into distal dendrites and dendritic spines.

61 lated in proximal dendrites but repressed in distal dendrites and display "bursting" translation.

62 ng-range biochemical signal propagation from distal dendrites and distal axons to neuronal nuclei is

63 tantial difference in Ca(2+) signals in fine distal dendrites and in the initiation of spreading seco

64 unts for the bias of NA and 5-HT contacts on distal dendrites and is partially responsible for the hi

65 nd postnatal week, it became concentrated in distal dendrites and preferentially associated with cort

66 ther with degenerative changes that begin in distal dendrites and progress proximally over time.

67 g revealed that AOB synapses are confined to distal dendrites and segregated from the proximally loca

68 complex spikes recorded intracellularly from distal dendrites and sharp waves in the electrocorticogr

69 sphorylated tau deposits first appear in the distal dendrites and somata, together with degenerative

70 AP-evoked Ca(2+) transients were enhanced in distal dendrites and spines in D(2) MSNs.

71 he localization of dopamine receptors on the distal dendrites and spines of pyramidal cells and on in

72 hosphorylated at Ser(237) is enriched in CA1 distal dendrites and that phosphorylation is reduced in

73 t to exclude the splice variant mGluR1b from distal dendrites and to drive it to the axon.

74 The distances between distal dendrites and/or distal axons and cell bodies of

75 h is localized in a punctate distribution in distal dendrites, and carbonic anhydrase isotype II (CAI

76 s localized to neuronal somata, proximal and distal dendrites, and dendritic spines.

77 patch) can be achieved, even for relatively distal dendrites, and simultaneous multiple-electrode de

78 mata/proximal dendrites (i.e., 0-26 mum) and distal dendrites ( approximately 130 mum dendrite length

79 These findings suggest that intermediate and distal dendrites are both the primary sites of dopamine

80 ion potential (AP) output, whereas inputs to distal dendrites are greatly attenuated and may largely

81 within GoC dendrites, and grc synapses onto distal dendrites are not amplified and are therefore ine

82 by onset of activity, while those targeting distal dendrites are recruited by sustained activity.

83 Our results identify SOM inhibition of distal dendrites as a key regulator of learning-related

84 ted cation current, Ih, but increased in the distal dendrites as a result of the activation of Ca2+ c

85 means that fine neuronal processes including distal dendrites, axons and axon terminals can be more r

86 nly degenerating nerve cell bodies, but also distal dendrites, axons and terminals.

87 cult to describe completely, particularly in distal dendrites, axons, and terminals of the forebrain.

88 upported inhibitory postsynaptic currents in distal dendrites better than GIRK2a.

89 inals everywhere synapsed on spines or small distal dendrites but as a population the postsynaptic st

90 cs and stimulus parameters indicate that the distal dendrites can support a coding scheme that is dif

91 MCU is uniquely enriched in hippocampal CA2 distal dendrites compared to proximal dendrites, however

92 rites, and robust dendritic signaling, these distal dendrites could serve as sites of intense intra-m

93 orally synchronized excitatory inputs at the distal dendrites could trigger plateau potentials in SPN

94 localized on somata, proximal dendrites, or distal dendrites depending on the specific CN subregion.

95 history-dependent spike back-propagation in distal dendrites, driven by locally generated Na(+) spik

96 In the distal dendrites, EPSC barrages evoked repetitive bursts

97 wever, brief glutamate uncaging at spines on distal dendrites evoked somatic up states lasting hundre

98 of plasma membrane-bound L-type channels in distal dendrites expands the view that L-type channels a

99 channels are unevenly distributed, with the distal dendrites expressing a more than fivefold greater

100 and middle dendrites, but recordings in the distal dendrites (>300 micron from the soma) showed that

101 Distal dendrites have mixed polarity, and reduction of P

102 would be generated in both the SAC soma and distal dendrites if (1) the Cl(-) equilibrium potential

103 contrast, HCN1 was targeted normally to CA1 distal dendrites in a TRIP8b knockout mouse that selecti

104 ls to optical mapping of membrane voltage in distal dendrites in acute mouse brain slices and in spon

105 of glutamate to mimic synaptic excitation of distal dendrites in conjunction with simultaneous imagin

106 act with excitatory inputs to pyramidal cell distal dendrites in the BLa.

107 on the plasma membrane by afferent input to distal dendrites in the VTA.

108 Impaired AMPA receptor transmission at distal dendrites in witness-susceptible mice was replica

109 stantia nigra pars reticulata (SNr) and with distal dendrites (in SNr) of DA neurons whose somas are

110 adenosine 3',5'-cyclic monophosphate in thin distal dendrites, in which protein-kinase A was activate

111 cate that the GABA reversal potential at the distal dendrite is more hyperpolarized than at the proxi

112 ownregulation of SK channel function in thin distal dendrites is a significant contributor to deaffer

113 plasma membrane, although their presence at distal dendrites is controversial.

114 Local translation of proteins in distal dendrites is thought to support synaptic structur

115 wnregulation of transient K+ channels in the distal dendrites may be responsible for some of the freq

116 ount of entorhinal inputs, arriving onto the distal dendrites, might determine the burst propensity o

117 cell bodies, thick proximal dendrites, thin distal dendrites, most dendritic spines, axon initial se

118 uron's dendritic tree, with synapses on more distal dendrites normally having a weaker influence on c

119 We conclude that the distal dendrite of GP neurons embodies a distinct dynami

120 of filopodia formation and retraction on the distal dendrites of adult-born GCs at their early matura

121 ons were apposed to soma and to proximal and distal dendrites of both cell types in both species.

122 ithin the PFC, DA terminals synapse onto the distal dendrites of both local circuit neurons and pyram

123 onses were much larger and peaked earlier in distal dendrites of C57BL/10 compared with those in C57B

124 intact entorhinal cortex, which projects to distal dendrites of CA1 but not area CA3, is critical fo

125 ed from outside-out patches excised from the distal dendrites of CA1 cells displayed a reduction in a

126 transient A-type K+ channels located in the distal dendrites of CA1 hippocampal pyramidal neurons an

127 C neurons that make synaptic contacts on the distal dendrites of CA1 neurons.

128 citatory temporoammonic (TA) synapses in the distal dendrites of CA1 pyramidal cells in rats are alte

129 neurons selectively target inhibition to the distal dendrites of CA1 pyramidal cells in the hippocamp

130 P) at the direct perforant path input to the distal dendrites of CA1 pyramidal neurons, but has littl

131 1, and activate interneurons that target the distal dendrites of CA1 pyramidal neurons.

132 he generation of large plateau potentials in distal dendrites of CA1 pyramidal neurons.

133 induced by a large plateau potential in the distal dendrites of CA1 pyramidal neurons.

134 tained in the LPP branch that innervates the distal dendrites of CA3: LTP did not reduce paired-pulse

135 monstrate that DA terminals synapse onto the distal dendrites of callosally projecting PFC neurons an

136 LM cells provided stronger inhibition to the distal dendrites of deep PCs relative to superficial PCs

137 study, we found that Bdnf mRNA localized to distal dendrites of dentate gyrus granule cells isolated

138 tory neurons (SOM-INs), which mainly inhibit distal dendrites of excitatory neurons, showed a decreas

139 udes producing greater calcium influx in the distal dendrites of fmr1-/y neurons.

140 the labeled boutons established synapses on distal dendrites of GABAergic local circuit neurons (LCN

141 sence of these channels in both proximal and distal dendrites of GP neurons.

142 how that LTP can indeed occur at synapses on distal dendrites of hippocamal CA1 neurons, even in the

143 Although bAPs in distal dendrites of hippocampal CA1 pyramidal neurons ar

144 at long-term potentiation of synapses on the distal dendrites of hippocampal CA1 pyramidal neurons do

145 all membranous intracellular compartments in distal dendrites of hippocampal CA1 pyramidal neurons in

146 + channels in cell-attached patches from the distal dendrites of hippocampal CA1 pyramidal neurons.

147 integration and long-term plasticity in the distal dendrites of hippocampal CA1 pyramidal neurons.

148 hat of the HCN1 isoform, are enriched in the distal dendrites of hippocampal CA1 pyramidal neurons; t

149 deafferentation of a segregated zone on the distal dendrites of hippocampal dentate gyrus granule ce

150 h have prominent populations on the soma and distal dendrites of hippocampal neurons, play a privileg

151 Focal activation of glutamate receptors in distal dendrites of hippocampal pyramidal cells triggers

152 induce the formation of new filopodia on the distal dendrites of immature adult-born GCs.

153 rom the serotonin system on the proximal and distal dendrites of individual motoneurons, we examined

154 y thus rely on activity modulations at those distal dendrites of involved pyramidal cells rather than

155 Distal dendrites of iSPNs from symptomatic HD mice were

156 Synaptic inputs to the distal dendrites of layer 5 pyramidal neurons in the pre

157 strates ACC terminals in apposition with the distal dendrites of LC neurons.

158 with sparse GABAergic collaterals targeting distal dendrites of neighboring SPNs, in a distance-depe

159 eously recording from the soma, proximal and distal dendrites of neocortical pyramidal cells in awake

160 eurobiotin was found in somata, proximal and distal dendrites of neurons that project from the mPFC t

161 ere it was possible to clearly visualise the distal dendrites of NK(1) immunoreactive neurones and qu

162 ivity-induced calcium influx in proximal vs. distal dendrites of oxytocinergic magnocellular neurons

163 nvestigate inhibition along the proximal and distal dendrites of PCs.

164 he primary dendrite of unipolar brush cells, distal dendrites of presumptive granule cells, and endin

165 Electrogenic phenomena in distal dendrites of principal neurons in the hippocampus

166 Neocortical layer 1 (L1) consists of the distal dendrites of pyramidal cells and GABAergic intern

167 ry, this investigation demonstrates that the distal dendrites of pyramidal cells, and varying percent

168 hibitory inputs to neurons in layer 1 and to distal dendrites of pyramidal cells.

169 in-expressing interneurons, which target the distal dendrites of pyramidal cells.

170 essing interneurons, neurons that target the distal dendrites of pyramidal cells.

171 n targets of 5-HT+ terminals were spines and distal dendrites of pyramidal cells.

172 gic interneurons, specialized in controlling distal dendrites of pyramidal neurons (PNs) and taking p

173 Signals arriving at the distal dendrites of pyramidal neurons (PNs) have little

174 erge onto layer 1 where they target not only distal dendrites of pyramidal neurons but also a sparse

175 aining BDNF messenger RNAs, which migrate to distal dendrites of pyramidal neurons, are selectively r

176 tatory synaptic drive targeting proximal and distal dendrites of pyramidal neurons, where the definin

177 taining in the lateral nucleus suggests that distal dendrites of pyramidal projection neurons in this

178 synaptic plasticity and memory, localizes to distal dendrites of rodent hippocampal neurons and neuri

179 n-dependent increase in the number of DVs in distal dendrites of RVM neurons that were immunoreactive

180 d 80% of them formed symmetric synapses with distal dendrites of SNr neurons.

181 C2 on the proximal dendrites and KCC2 on the distal dendrites of starburst cells results in a GABA-ev

182 TDP polarity through depolarizing effects at distal dendrites of striatal output neurons by modifying

183 of corticothalamic terminals in contact with distal dendrites of thalamocortical neurons and GABAergi

184 AR1) immunofluorescence intensity within the distal dendrites of the dentate gyrus granule cells, whi

185 This inhibition is directed to distal dendrites of the LG neurons, which allows for som

186 etory pathway in distal dendritic spines and distal dendrites of the mammalian brain.

187 aptic alpha4betadelta receptors expressed at distal dendrites of these cells.

188 nificant reduction of spine densities in the distal dendrites of these neurons in both sexes.

189 .0 microm in diameter) that terminate on the distal dendrites of type I neurons.

190 ty was located in somata and in proximal and distal dendrites of VPL relay cells and of RTN cells.

191 ular somata and long, thick dendrites; their distal dendrites often branched extensively and had long

192 identical, in most CINs cortical inputs onto distal dendrites only weakly entrain them, whereas proxi

193 s of synaptic active zones contacting either distal dendrites or proximal dendrites/somata do not cha

194 In more distal dendrites, potassium currents were activated by v

195 Synapses onto CA2 distal dendrites readily express plasticity, unlike the

196 put, leading to inhibition of pyramidal cell distal dendrites receiving aversive sensory excitation f

197 In addition, however, in distal dendrites receiving multiple inputs the receptor

198 On distal dendrites, representatives of both types were lab

199 ing to a loss of a cytoskeletal mechanism in distal dendrites required for dendrite stabilization and

200 ensory and cortical inputs onto proximal and distal dendrites, respectively, little is known about th

201 The SPN-induced surround inhibition in distal dendrites shunted effectively the corticostriatal

202 ion of responses to terminals that innervate distal dendrites (small type I cortical terminals).

203 t the late response had a source in the most distal dendrites (stratum moleculare) and a sink near th

204 napses onto dopaminergic and nondopaminergic distal dendrites, suggesting that various sources contri

205 ound that MCU deletion impairs plasticity at distal dendrite synapses.

206 ts therefore demonstrate a critical role for distal dendrite targeting interneurons in regulating pla

207 e proximal dendrite and more negative in the distal dendrite than the resting membrane potential, so

208 s occasionally made synapses onto spines and distal dendrites that received convergent synapses from

209 addition to conventional axonal outputs, has distal dendrites that serve both pre- and postsynaptic r

210 At the distal dendrite, the magnitude of long-term potentiation

211 In the middle and distal dendrites these increases normally peaked at the

212 rect input from entorhinal cortex onto their distal dendrites, these inputs produce a 5- to 6-fold la

213 nts with a lower level of expression in more distal dendrites; this selective immunoreactivity contra

214 tude of backpropagating action potentials in distal dendrites through downregulation of transient K+

215 over long distances from synapses located on distal dendrites to the nucleus to control gene expressi

216 tin alpha is required for its transport from distal dendrites to the soma and for its translocation i

217 ctions: (1) dendrodendritic synapses onto GC distal dendrites via their lateral dendrites in the supe

218 CF was inhibited by NPY, acting only at the distal dendrite, via Y(1) receptors.

219 However, the synaptic structure of C-group distal dendrites was quite similar to that observed for

220 rikarya contained infolded nuclei, and their distal dendrites were frequently found to be contacted b

221 Ca(2+) signals in distal dendrites were large in C57BL/10 neurons, and, if

222 l dendrites, and with the plasma membrane on distal dendrites, where it is often located near asymmet

223 ducens internuclear synaptic endings contact distal dendrites, whereas the majority of ATD synaptic e

224 tent" mechanism may be most effective in the distal dendrites, which are targeted by a variety of GAB

225 their increased electrotonic attenuation at distal dendrites, which can be counterbalanced by the in

226 n the most lateral neuropil corresponding to distal dendrites while gephyrin puncta are enriched on n

227 xon initial segment, somata, or proximal and distal dendrites, with each cell type implicated in a pa