ライフサイエンスコーパス: distensibility

1 ence in vascular stiffness (ascending aortic distensibility).

2 ness using cardiovascular magnetic resonance distensibility.

3 were concomitantly reduced, enhancing vessel distensibility.

4 assessed for diastolic and systolic area and distensibility.

5 lated endothelial dysfunction and diminished distensibility.

6 wed strong graded inverse relationships with distensibility.

7 ents present, which had a graded relation to distensibility.

8 n adiposity; homocysteine had no relation to distensibility.

9 tly regulates the development of ventricular distensibility.

10 eutrophic inward remodeling and an increased distensibility.

11 basal NO production influences large-artery distensibility.

12 , consistent with increased left ventricular distensibility.

13 levels showed no consistent association with distensibility.

14 d to their pulse pressure to assess arterial distensibility.

15 ring pulse wave velocity, aortic strain, and distensibility.

16 myocytes were stretched to investigate titin distensibility.

17 s in aortic function, such as loss of aortic distensibility.

18 ) on the whole arm to obtain arterial volume distensibility.

19 ng human myocardium because of reduced titin distensibility.

20 rkers of EMT, and negatively with esophageal distensibility.

21 ariates; ever HT use was not associated with distensibility.

22 pose tissue in determining brachial arterial distensibility.

23 us, and 0.90 (95% CI: 0.74, 1.10) for aortic distensibility.

24 V) was measured to determine arterial volume distensibility.

25 had more prominent effect on arterial volume distensibility.

26 ng of PAs, but not relaxin-induced increased distensibility.

27 tex, which may interact with PAs to increase distensibility.

28 rity, which is explained by resistive vessel distensibility.

29 o +3] mL/m(2), P=0.011) decreased and aortic distensibility (0.2 [-0.1 to +1.1] 10(-3) mm Hg(-1), P=0

30 aortic strain (23% versus 29%; P<0.0001) and distensibility (0.47 versus 0.64%/mm Hg; P=0.02).

31 .1% vs. -1.4 +/- 5.9%, p < 0.05), and aortic distensibility (0.69 +/- 0.86 x 10(-3) mm Hg vs. 0.04 +/

32 a decreased stress-induced measure of aortic distensibility (0.8 mm Hg(-3) [range 0.3 to 1.3 mm Hg(-3

33 or C2, 0.98 (95% CI: 0.86, 1.11) for carotid distensibility, 0.99 (95% CI: 0.90, 1.09) for Young's mo

34 8] versus 24 [15-40] mL, P=0.007) and aortic distensibility (1.5 [1.1-2.6] versus 2.7 [1.1-3.5] 10(-3

35 FDRs and BAVs had significantly lower aortic distensibility (1.7 +/- 1.4 x 10(-3) mm Hg and 1.4 +/- 2

36 er carotid Young's elastic modulus and lower distensibility 12 to 48 weeks after COVID-19 onset.

37 P = .046), and had lower baseline esophageal distensibility (13.0 vs 14.9 mm; P = .012).

38 nt in brachial PWV (-6%; P=0.14) and carotid distensibility (+18%; P=0.05).

39 ers, intima-media thickness, compliance, and distensibility; 2) aortic pulse wave velocity; 3) corona

40 imation had a higher percent contribution to distensibility (79% vs 21%), CSA (82% vs 18%), and HPZ (

41 sociated metabolic disturbances, to arterial distensibility (a marker of early arterial disease) in 1

42 We related arterial distensibility, a marker of vascular function known to b

43 The predictive value of ascending aortic distensibility (AAD) for mortality and hard cardiovascul

44 ependent changes in thoracic aortic area and distensibility (above that which occurs with aging) coul

45 ly higher than those based on dilatation and distensibility across all networks considered, highlight

46 Aortic distensibility (AD) is important for the prognosis of mu

47 obesity, FFA levels are elevated and aortic distensibility (AD) reduced in a pattern that predominan

48 s, ejection fraction, LV mass/EDV, or aortic distensibility (AD).

49 PV distensibility also predicted cardiovascular mortality i

50 d large (LAE) arterial elasticity and aortic distensibility among 6,282 participants in the Multiethn

51 ntrations are associated with lower arterial distensibility, an index of circulatory function relevan

52 rvature), aortic arch function (local aortic distensibility and arch pulse wave velocity [PWV]), and

53 ociations of ascending and descending aortic distensibility and area derived from cardiac magnetic re

54 stemic vascular resistance, increased aortic distensibility and arterial compliance, and, notably, si

55 Worse distensibility and beta were significantly associated wi

56 uggests a causal relationship between aortic distensibility and cerebral white matter hyperintensitie

57 with the lowest sex-specific tertiles of the distensibility and compliance coefficients (reversed) an

58 degrees of DA constriction decreased tissue distensibility and contractile capacity.

59 also show that VEGF increases microvascular distensibility and diameter.

60 ng the non-linearity between arterial volume distensibility and external pressure.

61 r Pulse Wave System at both ages, and aortic distensibility and LVMI were measured by cardiac magneti

62 defines the unfamiliar terms of compliance, distensibility and modulus and indicates how they are me

63 tively with aortic root and ascending aortic distensibility and positively with pulse wave velocity (

64 IMT was measured, and distensibility and stiffness parameter (beta) were calcu

65 tima-media thickness (cIMT) was measured and distensibility and stiffness were calculated to assess c

66 netic resonance images and calculated aortic distensibility and strain in 42,342 UK Biobank participa

67 The heritabilities of aortic distensibility and strain were 22% to 25% and 30% to 33%

68 ing and 11 and 21 loci for descending aortic distensibility and strain, respectively.

69 orrelates and genetic determinants of aortic distensibility and strain.

70 ffect of initial and additional treatment on distensibility and symptoms was evaluated in 7 and 5 pat

71 to be responsible for the compromised aortic distensibility and systemic compliance.

72 Dupilumab increased esophageal distensibility and was generally well tolerated.

73 m obtained by tonometry (n = 6,336); carotid distensibility and Young's elastic modulus at the caroti

74 onstrated hypertrophy, a further increase in distensibility, and a highly significant loss of myogeni

75 to derive aortic stiffness measures (strain, distensibility, and beta-stiffness index) at the aortic

76 rrent study reveals changes in artery sizes, distensibility, and blood flow pattern in young adult IU

77 ent is associated with decreased ventricular distensibility, and it may provide a causal mechanism li

78 arotid intima-media thickness (CIMT), aortic distensibility, and large and small arterial elasticity

79 loid severity parameters (e.g., keloid size, distensibility, and number).

80 Aortic pulse wave velocity, aortic distensibility, and other measures of aortic structure a

81 arotid artery intima-media thickness (CIMT), distensibility, and plaque assessed via repeated B-mode

82 res (endoscopic reference score), esophageal distensibility, and safety.

83 ures of pulse wave velocity (PWV) and aortic distensibility (AoD) in the thoracic aorta at baseline,

84 ; arterial compliance was measured by aortic distensibility (AoD).

85 - ECG gated, in which indexes such as aortic distensibility, aortic stiffness, and aortic compliance

86 Aortic function measures (distensibility, aortic strain, and pulse wave velocity)

87 changes in proximal thoracic aortic area and distensibility are associated with exercise intolerance

88 FMD and arterial distensibility are critical components of the exercise r

89 Aortic dimensions and distensibility are key risk factors for aortic aneurysms

90 We measured JV distensibility as the Valsalva-to-rest ratio of the vein

91 cle (eg, aortic arch pulse wave velocity and distensibility) as well as the various early and late ma

92 thelin-1, acting locally, regulates arterial distensibility, assessed by measuring pulse-wave velocit

93 tolic dysfunction, and an increase in aortic distensibility at all levels of the aorta, most pronounc

94 ess (pulse pressure/LVSV(index)), and aortic distensibility at rest and during intravenous dobutamine

95 ocity, aortic augmentation index, and aortic distensibility) at either age.

96 etecting significant differences in coronary distensibility between patients with DM and healthy agin

97 of external cuff pressure on arterial volume distensibility between peripheral arteries with differen

98 changes in proximal thoracic aortic area and distensibility (beyond that which occurs with normal agi

99 eveal a novel mechanism whereby loss of wall distensibility blunts endothelial cell protection to oxi

100 ccurred after T3-SCI with a 40% reduction in distensibility (both P < 0.05), and a 33% reduction in v

101 t ventricular structure, function and aortic distensibility), brain (brain volumes, white matter hype

102 sterol levels were also inversely related to distensibility, but less strongly than adiposity; homocy

103 , all antihypertensive agents improve aortic distensibility, but no agents do so directly; the nitrat

104 Dupilumab increased esophageal distensibility by 18% vs placebo (P < .0001).

105 ated with a decrease in Ao-A, Ao-P, and Ao-D distensibility by 2.3, 1.9, and 3.1 x 10(-3) mm Hg(-1),

106 Assessment of EGJ distensibility by EndoFLIP is a better parameter than LE

107 in response to cuff ischemia, carotid artery distensibility by high-resolution ultrasound, left ventr

108 NP would increase left ventricular diastolic distensibility by phosphorylating titin.

109 trasound-assessed internal jugular vein (JV) distensibility by ultrasound as a noninvasive tool to id

110 e significant differences in arterial volume distensibility changes were observed between the two arm

111 arotid intima-media thickness (cIMT) and the distensibility coefficient (DC), established measures of

112 Individuals in the lowest tertile of carotid distensibility coefficient (indicating greater carotid a

113 sure of carotid stiffness instead of carotid distensibility coefficient, and when we used generalized

114 ar outcomes included flow mediated dilation, distensibility coefficient, pulse wave velocity and a cl

115 t demonstrated a modest increase in arterial distensibility compared with those fed the depleted diet

116 Aortic distensibility correlated negatively with the aortic are

117 contrast to controls pulse wave velocity and distensibility correlated with age in patients (P=0.04 t

118 In patients with achalasia, EGJ distensibility correlated with esophageal emptying (r =

119 Even when LES pressure was low, EGJ distensibility could be reduced, which was associated wi

120 The esophageal distensibility (CSA vs pressure) was reduced in EoE pati

121 s in late-stage cardiomyopathy, when chamber distensibility declines.

122 dal alveolar pressure/area curve (reflecting distensibility) decreased with increasing positive end-e

123 Aortic distensibility decreases with age and vascular disease.

124 Pulmonary vascular (PV) distensibility, defined as the percent increase in pulmo

125 Esophageal distensibility, defined by the change in the narrowest m

126 hing more than 4500 g had the lowest carotid distensibility (difference in SDS, -0.22 x 10-3 kPa-1 [9

127 mm [95% CI, 0.03-0.11 mm]) and lower carotid distensibility (difference in SDS: 6 months, -0.04 x 10-

128 These data suggest that decreased carotid distensibility does reduce baroreflex function with age,

129 t HA is not essential for increased cervical distensibility during late pregnancy.

130 planimetry was used to determine esophageal distensibility during the baseline endoscopy and all sub

131 .3 +/- 3.5%, p = 0.88), and carotid arterial distensibility (ET: 0.97 +/- 0.56 vs. CT: 1.07 +/- 0.34

132 onstrictor responses were lower and vascular distensibility greater in arteries from spaceflight grou

133 he lowest, compared with the highest, aortic distensibility had an increased risk of hypertension (IR

134 nd LDL cholesterol and diastolic pressure to distensibility had been present at 9 to 11 years of age,

135 Peripheral arterial distensibility has been shown to be significantly lower

136 udies of one of these determinants, arterial distensibility, have led to results that now have clinic

137 diseased and healthy lung mechanics, such as distensibility, heterogeneity, anisotropy, alveolar recr

138 evaluate the relationship between esophageal distensibility, histology, and fibrostenotic complicatio

139 .51 (95% CI: 1.11 to 2.06) for lower carotid distensibility; HR: 1.19 (95% CI: 1.00 to 1.41) and 1.28

140 .27 (95% CI: 0.90 to 1.79) for lower femoral distensibility; HR: 1.25 (95% CI: 0.96 to 1.63) and 1.47

141 her ex vivo tests including decreased tissue distensibility, hydration, and elevated progesterone lev

142 Ultrasound-assessed JV distensibility identifies patients with chronic advanced

143 sed CV risk is associated with lower carotid distensibility, impaired baroreflex function and reduced

144 sal of both diastolic dysfunction and aortic distensibility impairment.

145 trasound was used to measure brachial artery distensibility in 294 healthy adolescents (aged 13 to 16

146 c phases permit measurements of large-vessel distensibility in a phantom model and that vessel disten

147 rating evidence for a causal role for aortic distensibility in development of aortic aneurysms.

148 wider understanding of the role of arterial distensibility in hypertension.

149 regional blood flow, blood vessel sizes, and distensibility in IUGR baboons (8 males, 8 females, 8.8

150 This study aimed to quantify arterial volume distensibility in patients with branch retinal vein occl

151 contractility and enhances left ventricular distensibility in patients with DCM, but not in subjects

152 evaluate longitudinal changes in esophageal distensibility in pediatric patients aged 3-18 years.

153 Relaxin also increased PA distensibility in SHRs (34+/-2 vs. 10+/-2% in SHRs, P<0.

154 ll-field measurements of both dilatation and distensibility in the aneurysmal aorta to identify the m

155 in all regions of the ECs and an increase in distensibility in the central regions when measured usin

156 cholesterol levels had an impact on arterial distensibility in the first decade of life.

157 Mild decrease in distensibility in the IUGR group was seen in the iliac b

158 and BNP improves left ventricular diastolic distensibility in vivo, in part by phosphorylating titin

159 Descending aortic distensibility increased (Ao-P: 9%; p = 0.009; Ao-D: 16%

160 cantly related to decreased ascending aortic distensibility, increased aortic arch PWV (p < 0.001), a

161 To assess diastolic distensibility independently of load/extrinsic forces, t

162 n vena cava diameter measured by ultrasound (distensibility index >15%) predicted fluid responsivenes

163 Intraoperative EGJ measurements including distensibility index (DI), cross-sectional area (CSA), a

164 essure (ePAD) of 16+/-9 mm Hg, and diastolic distensibility index (ratio of ePAD to end-diastolic vol

165 /-11 mm, ePAD of 18+/-7 mm Hg, and diastolic distensibility index of 0.06+/-0.04 mm Hg/mL (P<0.05 ver

166 nt effect of SBP, DBP and ageing on arterial distensibility indicates the potential underlying mechan

167 s training on both geometric and mechanical (distensibility) information.

168 We hypothesized that PV distensibility is abnormally low in patients with heart

169 EGJ distensibility is impaired in patients with achalasia an

170 Furthermore, PV distensibility is modifiable with selective pulmonary va

171 PV distensibility is reduced in patients with HF and pulmon

172 subject in the normal group had an arterial distensibility lower than 0.04% per mmHg, in comparison

173 ng decreased left ventricular compliance and distensibility (LVCD).

174 tions, we construct localized dilatation and distensibility maps throughout the aortic domain to serv

175 Measuring esophageal distensibility may be an important adjunct to the manage

176 Histology, distensibility measured by endoluminal functional lumen

177 an carotid wall area and no effect on aortic distensibility, measured at 3 separate anatomic sites.

178 sonography (n = 6,531 and 6,528); and aortic distensibility, measured using cardiac magnetic resonanc

179 nsibility in a phantom model and that vessel distensibility measurement in humans may be possible.

180 is study was to prospectively examine vessel distensibility measurements by using electrocardiographi

181 highlighting the benefit of obtaining local distensibility measures in TAA assessment.

182 Arterial distensibility measures, generally from pulse-wave veloc

183 Vessel distensibilities (mm Hg(-1)) were similar for elite rowe

184 do not prevent the decreased compliance and distensibility observed with healthy, sedentary aging.

185 /+) mice on control diet, an indication that distensibility of cerebral arterioles was increased in m

186 sociated with hypertrophy and an increase in distensibility of cerebral arterioles.

187 The shear moduli and distensibility of ECs were greater when using small inde

188 es in the compliance of the vessel wall, the distensibility of microvessels was measured before and 2

189 r findings demonstrated that arterial volume distensibility of peripheral arm arteries increased with

190 , carotid intimal-medial wall thickness, and distensibility of the carotid arteries using ultrasonogr

191 of the breast duct orifices, determining the distensibility of the duct, and developing a reliable te

192 We investigated whether assessment of the distensibility of the EGJ is a better and more integrate

193 Fundoplication restores distensibility of the EGJ to a level similar to normal s

194 We measured distensibility of the EGJ using an endoscopic functional

195 Distensibility of the esophagogastric junction (EGJ) lar

196 o have a significant role in the support and distensibility of the juxtacanalicular region under coll

197 and is highly dependent upon recruitment and distensibility of the pulmonary circulation.

198 s 356.8+/-113.4 mm(2)/m; P<0.01) and reduced distensibility of the thoracic aorta most pronounced at

199 vascular wavespeed by 7.1% and increased the distensibility of the vessels by 14.6%.

200 FG do not exhibit abnormal proximal thoracic distensibility or LV hypertrophy relative to individuals

201 reduced vascular stiffness (MRI-based aortic distensibility) or calcification (coronary artery calciu

202 t showed the most significant improvement in distensibility over time (1.41 vs 0.16-0.53 mm/y; P = .0

203 ssion is associated with improved esophageal distensibility over time in pediatric patients with EoE.

204 was associated with decreased carotid artery distensibility (P < .01) and increased Young's modulus (

205 ac cycle-dependent change in aortic area and distensibility (p < 0.0001) that correlated with diminis

206 maintain greater compliance (p < 0.0001) and distensibility (p < 0.001) than polytetrafluoroethylene

207 albuminuria were not associated with aortic distensibility (P = 0.26, 0.48, 0.45).

208 r IMT (P=0.03) and beta (P<0.0001) and lower distensibility (P<0.001).

209 6.0; P<0.01) and correlated with aortic root distensibility (P=0.004).

210 icant treatment effects for descending aorta distensibility (P=0.008) and strain (P=0.004) and aortic

211 fil or placebo led to a 24.6% increase in PV distensibility (P=0.015) in the sildenafil group only.

212 velocity (P=0.0098), strain (P=0.0099), and distensibility (P=0.015).

213 s moderate CR group having a 21% increase in distensibility (P=0.016) and an 8% decrease in pulse wav

214 distal), endoscopic reference score, distal distensibility plateau (functional luminal imaging probe

215 Aortic strain and distensibility polygenic scores had modest effect sizes

216 Baseline distensibility predicted the need for future stricture d

217 The carotid distensibility/pressure and elastic modulus/wall stress

218 Baseline esophageal distensibility provides a quantitative marker of tissue

219 Aortic dimensions, distensibility, pulse wave velocity, aortic arch angle,

220 medications independently predicted abnormal distensibility (R2=0.38, P=0.002) and beta (R2=0.25, P=0

221 A JV distensibility ratio >1.6 had predictive positive values

222 s from the calibration cohort with a high JV distensibility ratio (>1.6; n=42; median RAP, 4 mm Hg; p

223 dge pressure, 11 mm Hg), those with a low JV distensibility ratio (<=1.6; n=58; median RAP, 8 mm Hg;

224 ular diastolic function impaired, and aortic distensibility reduced in the obese.

225 mmHg, the overall changes in arterial volume distensibility referred to those without external pressu

226 tions were associated with impaired arterial distensibility (regression coefficient, -1.3% change in

227 icular relaxation and can impair ventricular distensibility resulting in diastolic dysfunction appare

228 [95% CI, 0.05-0.10 mm]) and a lower carotid distensibility (SDS, -0.05 x 10-3 kPa-1; [95% CI, -0.08

229 m [95% CI, 0.07-0.31 mm]) and lowest carotid distensibility (SDS, -0.16 x 10-3 kPa-1 [95% CI, -0.28 t

230 Decreased proximal aorta distensibility significantly predicted all-cause mortali

231 alculated values included CCA compliance and distensibility, systemic compliance, stroke volume and p

232 r signalling pathways associated with aortic distensibility (TGF-beta, IGF, VEGF and PDGF).

233 d glyceryl trinitrate both increase arterial distensibility, the former mainly through NO production.

234 A JV distensibility threshold of 1.6 was identified as the mo

235 in a multivariate analysis, thoracic aortic distensibility was a significant predictor of peak exerc

236 PV distensibility was associated with change in right ventr

237 PV distensibility was derived from 1257 matched measurement

238 At baseline, LV distensibility was greater in committed (21%) and compet

239 The distensibility was increased 45 +/- 15% by VEGF but this

240 e and age at symptom onset, lower esophageal distensibility was independently associated with increas

241 Descending aortic distensibility was inversely associated with future inci

242 PV distensibility was lowest in the pulmonary arterial hype

243 Brachial artery distensibility was measured by a noninvasive ultrasound

244 alloproteinase 9 (MMP-9) activity and tissue distensibility was observed in the cervix in both models

245 <18 years of age; 60% male), ascending aorta distensibility was reduced in comparison with published

246 EGJ distensibility was significantly higher in patients succ

247 ly higher by 2.3 m/s (P < 0.01) and arterial distensibility was significantly lower by 0.015% per mmH

248 Root distensibility was significantly lower in SG versus both

249 EGJ distensibility was significantly reduced in untreated pa

250 Arterial distensibility was significantly related to systolic and

251 Inverse associations with distensibility were also observed for insulin resistance

252 ions and mechanisms underlying loss of titin distensibility were assessed in failing human hearts.

253 Overall, increases in aortic distensibility were correlated with improvements in body

254 id intima-media thickness (cIMT) and carotid distensibility were measured as early markers of arteria

255 Stroke volume index and aortic distensibility were measured through cardiac magnetic re

256 Patients with less vena cava distensibility were not as likely to be fluid responsive

257 ffness (pulse wave velocity/analysis, aortic distensibility) were measured before run in and after 40

258 rial wall properties, such as CCA and aortic distensibility, were the same.

259 Specifically, decreased carotid distensibility with age may blunt the arterial barorefle

260 e FLIP detected a graded decrease in the EGJ distensibility with gastric distension following fundopl

261 4 mg/kg/d, 14 d) had no effect on increased distensibility with relaxin, but caused outward hypertro

262 es were shifted leftward, toward a decreased distensibility, with increasing age.

263 l because any therapeutic increase in aortic distensibility would decrease systolic pressure without

264 rtery intima-media thickness, carotid artery distensibility, Young's elastic modulus, and blood press