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1 oward NAD and cADPR homeostasis have evolved divergently.
3 ipotency reprogramming factors OCT4 and SOX2 divergently activate the two subgenomes of Xenopus laevi
4 chondrial respiration in diabetic hearts was divergently activated following hypoxia compared with co
6 Thus, engagement of distinct FcgammaR can divergently affect cytokine production and susceptibilit
7 of EVI1 for efficient interaction, and they divergently affect the ability of EVI1 to regulate gene
13 We show that TC and TAC mRNA abundances are divergently associated with clinical phenotypes, includi
14 It appears that the JNK pathway activity divergently attenuates IL-23p19 expression while enhanci
16 Mus81-Mms4 cleavage of cruciforms occurs at divergently but not convergently transcribed or nontrans
17 These three product classes were accessed divergently by taking advantage of the electronic and st
18 epoxidation and cobalt anodic corrosion, are divergently cascaded in nanoelectrospray (nESI) and can
19 er, Foxc1 and Arid5a programs in muscle were divergently changed by glucocorticoid regimens with oppo
20 eactions and control the site selectivity to divergently construct beta-, gamma-, and delta-lactams,
21 a broad family of bacterial deubiquitinases divergently evolved from the eukaryotic Ovarian Tumor (O
24 onserved residues in amino acid sequences of divergently evolved proteins are frequently observed; th
25 ved that proteins with promiscuous functions divergently evolved to acquire higher specificity and ac
26 es support the conclusion that all TGTs have divergently evolved to specifically recognize their cogn
27 l emergence of a new swine disease caused by divergently evolved viruses suggests that changes in swi
28 d oncogene, with distinct mutational classes divergently evolving to drive prostate tumorigenesis or
29 common intermediate, it was also possible to divergently exploit not only its nucleophilic nature to
30 and dnaA genes contains five promoters that divergently express the ribosomal protein L34 and the pr
31 and IL-35 (Ebi3-IL-12alpha heterodimer) were divergently expressed by T(reg) cell subpopulations in t
32 orting widespread functional compensation of divergently expressed duplicate genes by transcriptional
33 (AI) were used to identify 160 reliable and divergently fertile bulls for a dual strategy of targete
35 ermobacter thermautotrophicus is transcribed divergently from a gene (designated trpY) that encodes a
44 q detected short non-coding RNAs transcribed divergently from more than a thousand promoters in wild-
45 lthough RNA polymerase II (RNAPII) initiates divergently from most active gene promoters, productive
46 t activator of the pdxST operon, transcribed divergently from pdxR and responsible for the de novo sy
47 bed another gene, ptxS, which is transcribed divergently from ptxR and interferes with the enhancemen
49 ate kinase, is monocistronic and transcribed divergently from the idnD-idnO-idnT-idnR operon, which e
50 s have shown that mrpI, which is transcribed divergently from the mrp operon, encodes a recombinase c
51 nuclear-enriched lncRNA that is transcribed divergently from the neighboring proneural transcription
52 terminal domain, and its gene is transcribed divergently from the operon that it regulates and is sub
56 gene is located upstream and is transcribed divergently from the thrombospondin 3 (Thbs3) gene; 1352
59 ervention is sufficient to significantly and divergently impact host immunity, which could have impli
60 and black bream, express these old paralogs divergently in black- and clearwater habitats, while sti
61 tertwined with canonical initiation and used divergently in hundreds of dual-initiation promoters dur
65 trated that transcription of the operons was divergently initiated from adjacent start sites present
67 a ketoreductase, and the four genes reading divergently, left to right, include two open reading fra
68 Among them, two genes, pkn5 and pkn6, are divergently located on the chromosome and share a 46 bp
73 at rlrA lies in a 12-kb pathogenicity islet, divergently opposed to three putative sortase-anchored s
74 nd -35 promoter elements of the overlapping, divergently orientated promoters of hifA and hifBCDE, wh
75 The genes (hagA and hagB) were adjacent and divergently oriented and had no orthologs in the genomes
77 um was shown to possess a closely linked and divergently oriented equivalents of the regulator of per
79 in (GalR) encoded by the galR gene, which is divergently oriented from the structural genes of the ga
80 r xanthine dehydrogenase regulator (XdhR) is divergently oriented from xdhABC, which encodes xanthine
82 ified a regulatory gene (pvuIIC) between the divergently oriented genes for the restriction endonucle
83 e, DNGPs are significantly more likely to be divergently oriented on the chromosome; remarkably, appr
84 motifs within intergenic regions separating divergently oriented operons differs from the distributi
88 ing a bidirectional promoter shared with the divergently oriented TADA2L, which encodes a component o
89 rR) family of transcription factors; pecS is divergently oriented to pecM, which encodes an efflux pu
90 s are found together, closely juxtaposed and divergently oriented, at the locus of active transcripti
91 CDPGs, convergently-paired genes or CPGs and divergently-paired genes or DPGs) and three patterns (se
92 the C10-C11 diastereomers of cytostatin was divergently prepared (11 steps from key convergence step
93 lations in a "core-shell" configuration that divergently projects to the forebrain and hindbrain.
94 odimeric cytokines sharing a common subunit, divergently promote Th cell development and expansion.
95 tic impacts on gene expression at some loci, divergently promoting or repressing endosperm gene expre
96 find 766 genes that are likely to have been divergently regulated (DR) by Neanderthal haplotypes tha
97 ssion of PU.1, encoded by the Sfpi1 gene, is divergently regulated by Ikaros in distinct cell type-sp
104 iments revealed that decreasing Trpm4 levels divergently regulates nuclear localization of NFATc1.
107 ) and V(L) complexity appears to be evolving divergently, retaining diversity in V(L) perhaps to comp
109 A long-established inbred strain of mice was divergently selected for body weight for 50 generations.
110 es of microsatellite marker alleles in lines divergently selected for body weight from a base populat
111 anges during seed development in populations divergently selected for large and small seed size from
112 d in lines of Large White pigs that had been divergently selected on the basis of lean growth efficie
113 used to discriminate between lines of pigs, divergently selected over seven generations for componen
115 luding 10 from a Massachusetts population (5 divergently selected pairs) and 2 from a California popu
116 at surprisingly large genomic regions around divergently selected quantitative trait loci can be prot
117 ry predicts that the genetic architecture of divergently selected traits can influence whether sympat
118 equence upstream of the leukotoxin operon is divergently shared by P(lapT), which transcribes an argi
119 ver, genotypes responded to the environments divergently so that two populations displayed similar di
120 mouse, maternally contributed methylation is divergently targeted to species-specific sets of CpG isl
121 hnAB and phnR operons, which are transcribed divergently; the resulting mRNAs overlapped by 29 nucleo
122 signals for the two Ti plasmids have evolved divergently through changes in the opine synthase enzyme
123 cally identical, their methylomes may evolve divergently throughout their lifetime as a consequence o
124 cturally homologous bacterial toxins evolved divergently to bind calmodulin, an evolutionarily conser
126 eages of tissue-resident macrophages respond divergently to microbial, environmental and immunologica
128 udies have shown that these lineages respond divergently to similar immune environments within the tu
129 rformed on lncRNA-CCL2, which is transcribed divergently to the gene, CCL2, encoding a proatheroscler
130 7L and L206W respond similarly to VX-809 but divergently to VX-445 with P67L exhibiting little rescue
132 a single gene at the left end is transcribed divergently towards the telomere, and a tRNA gene separa
133 h UL37 glycoprotein cleavage products, which divergently traffic either through the secretory apparat
134 UL37) is internally cleaved and its products divergently traffic to mitochondria or are retained in t
135 ix identifiable genes organized as two units divergently transcribable from a 258-bp inter-genic regi
136 dentified the ToxT binding sites between the divergently transcribed acfA and acfD genes, which encod
137 contrast to what we previously found for the divergently transcribed acfA and acfD genes, which share
138 rylation events, leading to induction of the divergently transcribed agrBDCA operon and the RNAIII ge
140 lon genes such as nodABC, syrM and nodD3 are divergently transcribed and are separated by approximate
142 ed at 53.0 min on the E. coli chromosome, is divergently transcribed and is separated by 206 bp from
143 man Surf-1 and Surf-2 housekeeping genes are divergently transcribed and share a bi-directional, TATA
144 Additionally, these pairs were predominantly divergently transcribed and shared common gene regulator
145 ase PCR analyses show that hutA and tonB are divergently transcribed and that the remaining hut genes
146 tructure, within which dehI and dehR(I) were divergently transcribed and were flanked on either side
148 sion of the Gng3 gene, but expression of the divergently transcribed Bscl2 gene is not affected.
149 . enterocolitica psp locus is made up of two divergently transcribed cistrons, pspF and pspABCDycjXF.
150 cond operon that is upstream of bssDCABE and divergently transcribed contains two genes, tdiS and tdi
151 We suggest that basic building blocks of divergently transcribed core promoter pairs, in combinat
152 er with the genomic region that includes the divergently transcribed D. grimshawi DgYp1 and DgYp2 gen
153 ctional promoters regulate expression of the divergently transcribed dihydrofolate reductase (dhfr) a
154 pt abundance is coregulated with that of the divergently transcribed DPB3 gene, which codes for a sub
155 vary gland polytene chromosomes contains the divergently transcribed E63-1 and E63-2 ecdysone-inducib
157 ate that MsvR regulates transcription of the divergently transcribed fpaA-rlp-rub operon in Methanoth
160 odes a LysR-type transcription factor and is divergently transcribed from a promoter overlapping that
161 a tested, including M. tuberculosis, oxyR is divergently transcribed from ahpC, a gene encoding a hom
163 ed as part of the lsrACDBFG operon, which is divergently transcribed from an adjacent lsrRK operon.
164 e clinical isolates by mecR1 and mecI, genes divergently transcribed from mecA that encode a signal t
166 e is closely linked to the psp operon and is divergently transcribed from one major and two minor sig
168 ly downstream of the prpBCDE operon; hemB is divergently transcribed from prpBCDE and is separated fr
169 d capsule biosynthesis (synABCD) operons are divergently transcribed from putative promoters located
171 le of IcaR, encoded within the ica locus but divergently transcribed from the biosynthetic genes.
172 l activator, CbbR, encoded by cbbR, which is divergently transcribed from the cbbLS genes (encoding f
174 1 gene, which is immediately adjacent to and divergently transcribed from the cif-containing, three-g
175 The fliX gene is located upstream and is divergently transcribed from the class III flagellar gen
176 , and EC-enriched lncRNA, GATA2-AS1, that is divergently transcribed from the EC-enriched development
177 An open reading frame just upstream and divergently transcribed from the fimA operon was identif
178 egulator (gene PA2082, here called kynR), is divergently transcribed from the kynBU operon and is hig
179 cl/GalR family of repressor proteins, and is divergently transcribed from the malEFG gene cluster, wh
180 le L-lactate dehydrogenase (ldh1, SACOL0222) divergently transcribed from the NO.-detoxifying flavohe
181 s and also that the LysR-type regulator AlsR divergently transcribed from the operon is required for
186 he benM gene is immediately upstream of, and divergently transcribed from, benA, and a possible DNA b
189 sence, in the flanking upstream region, of a divergently transcribed gene (phhR) encoding an activato
190 found that OxyR2 is required to activate its divergently transcribed gene ahpC, encoding an alkylhydr
192 by Ape1, an AraC-type regulator encoded by a divergently transcribed gene immediately upstream of PI-
193 of kayak (kay) and fos intron gene (fig), a divergently transcribed gene located in a kay intron, ut
194 tween 23,752 genes, we identified a class of divergently transcribed gene pairs, representing more th
197 e H2A and two for histone H2B located in two divergently transcribed gene pairs: HTA1-HTB1 and HTA2-H
198 ted genetic evidence that SgrR activates the divergently transcribed gene sgrS, which encodes a small
202 lor A3(2) and was found to lie adjacent to a divergently transcribed gene, scbR, which encodes a gamm
205 gion encompasses the upstream regions of two divergently transcribed genes and contains a sequence mo
208 ts performed in L. brevis confirmed that the divergently transcribed genes LVIS1988, LVIS1987 and LVI
211 dE2F2/dREAM binding sites are enriched at divergently transcribed genes, and the majority of genes
213 e simocyclinone biosynthetic cluster are two divergently transcribed genes, simR and simX, encoding p
214 H3K36me2 is scarce in regions upstream of divergently transcribed genes, telomeres, silenced matin
215 evealed that this DNA fragment contained two divergently transcribed genes, tetA and tetR, encoding p
218 located between, and transcription from, the divergently transcribed H3-H4 genes nucleates HLB format
221 nstrate transcriptional coupling between the divergently transcribed ilvY and ilvC promoters of the i
222 Eukaryotic promoter regions are frequently divergently transcribed in vivo, but it is unknown wheth
224 We propose that the RNA exosome protects divergently transcribed lncRNA expressing enhancers by r
229 and possibly ogt and might be regulated by a divergently transcribed LysR-type regulator encoded by a
230 mined the behavior of two promoters from the divergently transcribed M. tuberculosis genes acr/hspX/R
232 se Thbs3 is located just downstream from the divergently transcribed metaxin gene (Mtx), which encode
235 S. Typhimurium-encoded orthologues of two divergently transcribed OmpR-regulated operons (SL1068-7
236 esults reveal differential regulation of the divergently transcribed ooc transcriptional units, highl
237 on revealed a 282-bp intergenic region and a divergently transcribed open reading frame, designated p
238 the isolation of mutations in two adjacent, divergently transcribed open reading frames (eri-6 and e
239 onal coupling between the promoters of other divergently transcribed operons is investigated, additio
240 gment encoding five genes, parCBA/DE, in two divergently transcribed operons promotes stable maintena
241 anized as two subclusters, consisting of two divergently transcribed operons, rbr-fprA-hrb and rbo-ru
242 he catabolic activities are localized to two divergently transcribed operons, the siaPT operon and th
243 more distal 5' sites that also regulate the divergently transcribed ORF45-ORF46-ORF47 gene cluster.
244 entified a second histone H4 gene (hH4-2), a divergently transcribed pair of genes that encode H2A an
246 20-nucleotide intercistronic region with the divergently transcribed pbp4 gene, which encodes the tra
247 moter and regulatory regions of fimA and the divergently transcribed pepO gene, which encodes a zinc
248 BP 1, while repressing the expression of the divergently transcribed pilM gene, the first gene in the
249 ch zone was in the CpG island containing the divergently transcribed promoter separating the DHFR and
250 nerated in the region between closely spaced divergently transcribed promoters could serve to couple
251 thylation-free CpG islands spanning the dual divergently transcribed promoters from the human TATA bi
252 transcriptional coupling that occurs between divergently transcribed promoters is likely to serve a p
253 ation-free CpG islands associated with dual, divergently transcribed promoters possess an independent
256 or, PigZ, which represses transcription of a divergently transcribed putative resistance-nodulation-c
257 r extension analysis to demonstrate that the divergently transcribed regB and senC-regA-hvrA transcri
259 , was cloned and shown to be adjacent to and divergently transcribed relative to the putative ABC-typ
260 d between defined enhancers and placed among divergently transcribed reporter genes (white and lacZ)
263 ate the raffinose-dependent stimulation of a divergently transcribed second promoter (P(A)) directing
264 ified, one of which was shown to contain the divergently transcribed solR and solI genes, the luxR an
265 promoters for the spuABCDEFGH operon and the divergently transcribed spuI gene of unknown function.
266 ively regulates the transcription of its own divergently transcribed structural gene in an inducer-in
267 tream Egr2 binding sites lie proximal to the divergently transcribed succinate dehydrogenase C gene,
269 contains the oriT site and the two flanking, divergently transcribed tra operons that encode the DNA
270 esignated cbbRRS, are juxtaposed between the divergently transcribed transcription activator gene, cb
275 pe transcriptional regulatory gene, ceoR, is divergently transcribed upstream of the structural gene
276 ral and accessory genes (ureDABCEFG) and the divergently transcribed ureR, which codes for an AraC-li
278 1.2-kb Fab-7 DNA fragment was placed between divergently transcribed white and lacZ test promoters an
279 show that SET domain-containing 5 (Setd5) is divergently transcribed with Gt(ROSA26)Sor, is necessary
285 B and tagDEF operons, which are adjacent and divergently transcribed, encode genes responsible for ce
293 ontain documented promoters or occur between divergently transcribing coding regions, and hence may b
294 our data provided mechanistic insights into divergently transcriptional regulation of KPNA2, thus po
295 enitors give rise to the ENS, and that these divergently utilize endothelin signaling to support migr
297 uctural platform from which proteins evolved divergently, with some losing inhibitory functions.
298 n initiation point analysis and found to map divergently within and near an AT-rich element flanked b