ライフサイエンスコーパス: dodecamer

1 imer derived from peptide 3(F20Cha), forms a dodecamer.

2 crystal structure of a substrate-bound DegP dodecamer.

3 binding site on the interior surface of the dodecamer.

4 y synthesizing a homologous series up to the dodecamer.

5 antly a monomer and the activated state is a dodecamer.

6 binding does not require its assembly into a dodecamer.

7 out 20% of the trimer is incompetent to form dodecamer.

8 lU(DeltaI) hexamer binds one end of the HslV dodecamer.

9 base pairing remained intact throughout the dodecamer.

10 paired C and G bases in the CCATGCGCTGAC DNA dodecamer.

11 erminus of each subunit in the centre of the dodecamer.

12 osine on the structure of the Dickerson-Drew dodecamer.

13 sociated off center with a single layer of a dodecamer.

14 ystallographic 2-fold symmetry form the SpeG dodecamer.

15 al arrangement about a central cavity form a dodecamer.

16 uciform tetramers assemble into a triangular dodecamer.

17 re both 750-kilodalton (kDa) alpha(6)beta(6) dodecamers.

18 y could be the most stable species for Abeta dodecamers.

19 Abeta42 alone produces oligomers as large as dodecamers.

20 group in rF:G pairs of the investigated RNA dodecamers.

21 are thought to do so only as fully assembled dodecamers.

22 do-tridecamer, and spermidine for the pseudo-dodecamers.

23 er oligopeptides to simulate the spectra for dodecamers.

24 for the assembly and secretion of functional dodecamers.

25 isulfide-cross-linked, trimeric subunits and dodecamers.

26 culture as trimeric subunits rather than as dodecamers.

27 l oligomers, including dimers, hexamers, and dodecamers.

28 nstead of an excess of HOCl, as observed for dodecamers.

29 to three distinct oligomers: nonamer (9mer), dodecamer (12mer), and the previously characterized octa

30 ynamics trajectories of two solvated A-tract dodecamers: 1D89, d(CGCGA(6)CG), and 1D98, d(CGCA(6)GCG)

31 ics of opening of AT/TA basepairs in the DNA dodecamer 5'-d(GCTATAAAAGGG)-3'/5'-d(CCCTTTTATAGC)-3'.

32 Z3dU) and 7-deaza-dG into the Dickerson-Drew dodecamers 5'-d(C (1)G (2)C (3)G (4)A (5)A (6)T (7)T (8)

33 structure and dynamics of the Dickerson DNA dodecamer [5'd(CGCGAATTCGCG)2] in solution have been inv

34 els of insoluble amyloid-beta (Abeta), Abeta dodecamers (Abeta*56), prefibrillar soluble oligomers, a

35 f the active clones were tested as synthetic dodecamers, Ac-AGX(8)GA-NH(2).

36 minal arms are located on the outside of the dodecamer, accessible for interaction with client protei

37 structure into a 19-A cryo-EM map of a VacA dodecamer allows us to propose a model for how VacA mono

38 Dodecamers also show utility in the analysis of gammadel

39 Inspection of the 5' and 3' ends of the dodecamers also supplies new information on the fraying

40 ntal observation, for (i) the Dickerson-Drew dodecamer and (ii) three oligomers containing A-tracts.

41 trates that the dimeric interface within the dodecamer and a Lys-Trp-Lys triad at the center of the r

42 In this study, we used two forms of SP-D, a dodecamer and a shorter fragment containing the trimeric

43 used to build both the catalytically active dodecamer and catalytically inactive dimer.

44 entify the enzyme(s) that cross-links the 7S dodecamer and characterize its expression in the kidney

45 y 0.6 kcal/mole nucleotide for the Dickerson dodecamer and declines for longer oligonucleotides.

46 181A, which, as expected, disrupts the Hsp21 dodecamer and decreases chaperone activity.

47 termined low-resolution structures of a VacA dodecamer and heptamer, as well as a 3.8- angstrom struc

48 ing the tetramer, conjugates of the octamer, dodecamer and hexadecamer elicited IgG LPS antibodies af

49 ose-deoxyribose mutations in a single-strand dodecamer and in trinucleotide models suggest that in th

50 multiple subunit contacts between the CaMKII dodecamer and the F-actin cytoskeleton that stabilize th

51 with natural SP-D (10 micro g/ml) containing dodecamers and higher-order forms exhibited aggregation

52 e the different lengths of DNA in the pseudo-dodecamers and pseudo-tridecamer, all three structures f

53 metry to investigate glutamate dehydrogenase dodecamers and serum amyloid P decamers as a function of

54 mers, trimers, and homomultimers as large as dodecamers and that CsmA directly interacts with the Fen

55 n that this family of proteins assemble into dodecamers and their quaternary structure is entirely cr

56 a DNA segment with 12 base pairs (Dickerson dodecamer) and a (8,8) SWNT in water, with counterions t

57 ling model that active Vps4 is a double-ring dodecamer, and argue that, like other type I AAA ATPases

58 emble in a tetrahedral arrangement to form a dodecamer, and five dodecamers pack together to form an

59 metal site is necessary for formation of the dodecamer, and metal binding at this site facilitates ol

60 Portal, a dodecamer, and motor, a pentamer, form two concentric ri

61 atomic models for the T4 portal monomer and dodecamer, and we fit the dodecamer into the cryo-electr

62 rs assemble hierarchically to form hexamers, dodecamers, and annular porelike structures.

63 he CD spectra of analogous peptoid hexamers, dodecamers, and pentadecamers, composed entirely of eith

64 d that the two HslV(6) rings in the protease dodecamer are activated independently rather than cooper

65 he activation-competent species, whereas the dodecamers are a storage form.

66 Dodecamers are able to detect early stage CD4(+)CD8(+)do

67 In particular, dodecamers are able to detect two- to fivefold more anti

68 Architecturally conserved viral portal dodecamers are central to capsid assembly and DNA packag

69 Compared with hexamers, Lon dodecamers are much less active in degrading large subst

70 Soon after (>/=10 min), dodecamers are observed to seed the formation of extende

71 The CII dodecamers are, however, dynamic and rapidly exchange su

72 hemoglobin chains that are assembled into 12 dodecamers arranged at the periphery of the complex arou

73 Here we report a peptide-MHC (pMHC) dodecamer as a "next generation" technology that is a si

74 ilizing the prepore into a poorly structured dodecamer as visualized by electron microscopy.

75 nt species, pea, wheat, and Arabidopsis, are dodecamers as determined by nano-electrospray mass spect

76 forms a scaffold on which twelve hemoglobin dodecamers assemble.

77 .X hydrogen bonds must be weakened to effect dodecamer assembly and that the molecular mechanism invo

78 Furthermore, we observe PGAM5 dodecamer assembly into filaments both in vitro and in c

79 s of portal cysteines in subunit folding and dodecamer assembly.

80 R indicate that this photoinduced hexamer-to-dodecamer association occurs through intermolecular beta

81 Combined with photoinitiated hexamer-to-dodecamer associations in the presence of the photorespo

82 ially isostructural with the native unlinked dodecamer at 1.9 A.

83 th the sodium and the potassium forms of the dodecamer at high resolution indicate that the original

84 A-form RNA segment and a helical B-form DNA dodecamer at natural (13)C abundance.

85 Escherichia coli Lon also interact to form a dodecamer at physiological protein concentrations.

86 versatile enzyme is known to form functional dodecamers at its optimal pH and is thought to work in c

87 shown that AT can homooligomerize to form a dodecamer, AT(12), composed of a tetramer of trimers, AT

88 UV melting studies of a dodecamer bearing one, two, or three nonadjacent modifie

89 ntact with the membrane is buried within the dodecamer before protonation.

90 olfataricus (Sso-KARI) is unusual in being a dodecamer, bispecific to NADH and NADPH, and losing acti

91 , does not significantly form the hexamer or dodecamer but instead produces a mixture of smaller olig

92 ation of lysyl-derived cross-links in the 7S dodecamer but not in the NC1 domain.

93 K not only inhibits the formation of Abeta42 dodecamers, but also removes preformed Abeta42 dodecamer

94 6M34A and Cx26V84L are stable as hexamers or dodecamers, but Cx26T135A and Cx26P87L oligomers are not

95 In addition, human dodecamers, but not full-length human trimers, efficient

96 ifferent molecular forms of SP-D showed that dodecamers-but not trimeric subunits-mediate optimal agg

97 duct, G[8,5-Me]T, embedded in a solvated DNA dodecamer by means of quantum mechanics/molecular mechan

98 e we report fibril propagation of an Abeta42 dodecamer called large fatty acid-derived oligomers (LFA

99 ted complexes demonstrated that each HSP18.1 dodecamer can bind the equivalent of 12 MDH monomers, in

100 Although SP-D dodecamers can selectively augment metalloproteinase act

101 The DNA dodecamer CATGGGCCCATG in a crystal structure of resolut

102 form propeptide hexamers by binding to other dodecamers, causing aggregation.

103 ost active compounds bound to an AT-rich DNA dodecamer (CGCGAATTCGCG)2 and using DSC were found to in

104 tion structure of the self-complementary DNA dodecamer (CGT_GACGT_TACG above GCAT_TGCAG_TGC] which co

105 her-order assembly that we have modeled as a dodecamer composed of two stacked hexameric rings.

106 SP-D is assembled predominantly as dodecamers consisting of four homotrimeric subunits each

107 he octamers are tetramers of dimers; and the dodecamers contain two trimer subunits surrounded by thr

108 The solution structures of a duplex DNA dodecamer containing a cis-syn cyclobutane thymine dimer

109 herefore, the structure of a double-stranded dodecamer containing a tetrahydrofuran apurinic lesion a

110 on of the NMR measurements collected on four dodecamers containing a substantial set of dinucleotide

111 The dodecamer contains the TATA box of the adenovirus major

112 t for antiviral and anticancer drugs, pseudo-dodecamer crystals were soaked with one such antiviral a

113 d the three-dimensional structure of the DNA dodecamer d(CGC[iG]AATTTGCG) (denoted iG-DODE) by X-ray

114 For example, the conversion of dodecamer d(CGCAAATTCGCG) from hairpin to random coil is

115 However, the MD structure of the dodecamer d(CGCGAATTCGCG) is not highly sensitive to whe

116 n Fe(II).bleomycin A2 and the Dickerson-Drew dodecamer d(CGCGAATTCGCG)2 is presented.

117 The approach is demonstrated for the DNA dodecamer d(CGCGAATTCGCG)2, where direct interactions ar

118 The structure of the dodecamer d(CGCGAATXCGCG)(2), in which X = Z3dU, 5-(3-am

119 onucleotides based on the self-complementary dodecamer d(CGCTAATTAGCG) were synthesized.

120 The solution structure of a DNA dodecamer d(GGCAAAAAACGG)/d(CCGTTTTTTGCC) containing an

121 ons were carried out for the double-stranded dodecamer d(GGTATATAAAAC), in which a transition from A-

122 The dodecamer d[CGCA(Ap)ATTTGCG]2 was investigated, and we a

123 simulations were performed on the duplex DNA dodecamers d(CGCGAA TT CGCG): d(CGCGAATTCGCG) and d(GCAC

124 The DNA molecule studied is the dodecamer [d(CGCGAGCTCGCG)]2.

125 ution solution structure of the cross-linked dodecamer [d(GCATCCGGATGC)]2 (the cross-linked guanines

126 The structure of the DNA duplex dodecamer, d(CCTCTGGTCTCC.

127 tential to the structure refinement of a DNA dodecamer, d(CGCGAATTCGCG)(2), for which NOE and dipolar

128 e 1.7 A X-ray crystal structure of the B-DNA dodecamer, [d(CGCGAATTCGCG)] (DDD)-bound non-covalently

129 The structure of the modified Dickerson-Drew dodecamer (DDD) in which guanine at position G(4) has be

130 th sequence CGCGAATTCGCG, the Dickerson-Drew dodecamer (DDD), established a unique geometry of the ce

131 ong-timescale dynamics of the Drew-Dickerson dodecamer (DDD: d(CGCGAATTGCGC)2) a prototypical B-DNA d

132 uble-stranded B-DNA dodecamer (the Dickerson Dodecamer, DDD, [d(CGCGAATTCGCG)]2) associated with a cy

133 uits a hexamer-forming peptide to form mixed dodecamers demonstrates that one species can dictate the

134 ds to predict the structure of two new B-DNA dodecamers, determined herein by means of 1H nuclear mag

135 with North-locked sugars (RNA-like) into the dodecamer did not greatly affect duplex formation or mel

136 We found that HypT dodecamers dissociated into tetramers in the presence of

137 The OrnDC L30a dodecamer dissociates into dimers at high pH in the pres

138 simulations were performed on models of the dodecamer DNA double-stranded segment, [d(CGCGAATTCGCG)]

139 stal structure of the non-self-complementary dodecamer DNA duplex formed by d(CG[5BrC]ATAT-TTGCG) and

140 irs were attached to selected positions of a dodecamer DNA duplex with a known NMR structure, and eig

141 tion exhibits similar time scales to that of dodecamer DNA.

142 cal B-DNA conformation of the Dickerson-Drew dodecamer duplex [[d(CGCGAATTCGCG)]2, (ODN 1)].

143 n structure of the nitrous acid cross-linked dodecamer duplex [d(GCATCCGGATGC)]2 (the cross-linked gu

144 t the two independent iG.T base pairs in the dodecamer duplex adopt different (one in Watson-Crick an

145 he 5'-CpG-3' sequence was monitored within a dodecamer duplex by NMR spectroscopy, in situ, using a s

146 The crystal structure of the DNA dodecamer duplex CATGGGCCCATG lies on a structural conti

147 ined four crystal structures of a B-form DNA dodecamer duplex containing ClU:A or ClU:G base pairs.

148 the 8-OG:G pair on a self complementary DNA dodecamer duplex d(CGCGAATT(8-O)GGCG)(2).

149 A molecular dynamics simulation of the dodecamer duplex d(CGCGAATTCGCG) using the particle mesh

150 The solution structure of the dodecamer duplex d(CTTTTGCAAAAG)(2)and its 2:1 complex w

151 hotoproducts formed in a TATA box-containing dodecamer duplex sequence in the presence or absence of

152 tosecond resolution, at the surface of a DNA dodecamer duplex whose native structure remains unpertur

153 e at atomic resolution determined for an RNA dodecamer duplex with rF opposite G manifests only minor

154 solution structure of a second cross-linked dodecamer duplex, [d(CGCTACGTAGCG)]2, which shows that t

155 onformations of these ANA analogues in a DNA dodecamer duplex, we have modeled a duplex of an all-C3'

156 atom of a single guanosine residue in a DNA dodecamer duplex.

157 g cationic side chains in the Dickerson-Drew dodecamer duplex.

158 five examples of A-tract DNA oligonucleotide dodecamer duplexes for which crystal structures are avai

159 their behavior in the context of hexamer and dodecamer duplexes were carried out, with comparison to

160 CD spectroscopic studies of two related DNA dodecamer duplexes, d(CGCAAATTTGCG)(2) (A(3)T(3)) and d(

161 nm) clearly detects two transitions for this dodecamer, each giving a pronounced change in ellipitici

162 ence of a functional regulation of the dimer-dodecamer equilibrium in vivo.

163 analysis of the pH dependence of the trimer-dodecamer equilibrium revealed a near physiological pK(a

164 ition (called structure X here) to the B-DNA dodecamer family of X-ray structures.

165 tationally investigate four classes of Abeta dodecamers: fibril, fibril oligomer, prefibril/preglobul

166 hways and provide a candidate in the Abeta42 dodecamer for the primary toxic species in Alzheimer's d

167 ls that tightly spooled DNA about the portal dodecamer forces a conformation that is significantly di

168 tution d-Pro36-l-Pro37 abolished hexamer and dodecamer formation by Abeta42 and produced an oligomer

169 re of PGAM5 that reveals the determinants of dodecamer formation.

170 udy shows that the M1 site strictly controls dodecamer formation.

171 al pH, VacA is predominantly a water-soluble dodecamer formed by two apposing hexamers.

172 A cocrystallization experiment in which a dodecamer-forming peptide recruits a hexamer-forming pep

173 The 480 kDa dodecamer forms a three-tiered assembly, in which DnaC a

174 The hexamer and dodecamer forms coexist in solution.

175 The thermodynamic stability of nine dodecamers (four DNA and five RNA) of the same base comp

176 rotection (hydroxyl radical) for Dps protein dodecamers from Bacillus anthracis (Ba) since crystal st

177 decamers, but also removes preformed Abeta42 dodecamers from the solution.

178 can catalyze full-length DNA synthesis on a dodecamer GNA template.

179 The hemoglobin dodecamer has a molecular 3-fold axis of symmetry that r

180 A guanine-rich PNA dodecamer having the sequence H-G4T4G4-Lys-NH2 (G-PNA) h

181 onformational features of the Dickerson-Drew dodecamer in both the solid state and the aqueous liquid

182 w of the conformational space sampled by the dodecamer in solution and permit one to analyze fluctuat

183 solution structure of an oxaliplatin-GG DNA dodecamer in the AGGC sequence context by 2D NMR studies

184 The precursor form of API assembles into a dodecamer in the cytosol and maintains this oligomeric f

185 The CcmK3-CcmK4 heterohexamers form stacked dodecamers in a pH-dependent manner.

186 eaved recombinant rat and natural human SP-D dodecamers in a time- and dose-dependent manner, which w

187 We show that SpeG forms dodecamers in solution and in crystals and describe its

188 on distribution around (5'-CGCGCGCGCGCG-3')2 dodecamers in solution in B-DNA, A-RNA, Z-DNA and Z-RNA

189 eover, the observed facultative formation of dodecamers in solution suggests that carboxysome shell p

190 on cryo-microscopy, we show that PGAM5 forms dodecamers in solution.

191 tructures for cisplatin-GG and undamaged DNA dodecamers in the AGGC sequence context and have compare

192 re, six DHO and six ATC chains form a hollow dodecamer, in which the 12 active sites face an internal

193 stabilize the bend direction in the A-tract dodecamers include propeller twisting of AT base-pairs,

194 , and activation, we aimed to dissociate the dodecamers independently of DNA and to analyze HOCl-depe

195 cromolecules attached to both ends of an mPE dodecamer induce the foldamer to collapse into a presume

196 portal monomer and dodecamer, and we fit the dodecamer into the cryo-electron microscopy density of t

197 g of HypT to DNA induces dissociation of the dodecamers into dimers and tetramers, thus forming the D

198 ble of recent NMR data collected on four DNA dodecamers involved in nucleosome positioning.

199 The pUL6 portal dodecamer is anchored at one vertex of the capsid by int

200 This SpeG dodecamer is asymmetric except for the one 2-fold axis a

201 We find that PGAM5 oligomerization into a dodecamer is not only essential for catalytic activation

202 The 7S dodecamer is recognized as an important structural cross

203 Although the 7S dodecamer is stabilized by covalent cross-linking, the m

204 The dodecamer is straightforward and inexpensive to produce

205 sequence, and crystal form as the "Dickerson dodecamer", is refined against a complete, low-temperatu

206 simulations, when compared with those of the dodecamer itself, show that incorporation of the analog

207 Thus, the Vps4 dimer and dodecamer likely form distinct but overlapping interface

208 biochemical studies suggest that mtMCM is a dodecamer, likely a double hexamer (dHex).

209 activation of HSP16.9 occurs by shifting the dodecamer <--> dimer equilibrium in favor of free dimers

210 d an A-to-G transition in a highly conserved dodecamer motif between DLK1 and GTL2.

211 determined for double helix formation by DNA dodecamers near 25 degrees C are in the range of 0.72-0.

212 Results for RNA and DNA dodecamers obtained at higher temperatures, and literatu

213 surface, suggesting that the assembly of the dodecamer occurs through head-to-tail interactions of th

214 iana, the overall architecture of which is a dodecamer of (beta/alpha)8 barrels, similar to the major

215 10.5, 6.3, 5.0, and 4.2 nm, identified as a dodecamer of globin chains ([a+b+c]3d3, 213 kDa), the di

216 t be due to the oligomeric nature of EmrE, a dodecamer of helices was constructed based on the result

217 G4T4G4-Lys-NH2 (G-PNA) hybridizes with a DNA dodecamer of homologous sequence to form a four-stranded

218 x contains the portal protein, a gear-shaped dodecamer of radially disposed subunits with a central c

219 The structure of a crosslinked B -DNA dodecamer of sequence C-G-C-G-A-A-T-T-C-G-C-G has been s

220 2-A crystal structure, PdxS is a cylindrical dodecamer of subunits having the classic (beta/alpha)8 b

221 e terminase complexed with the portal vertex dodecamer of the prohead.

222 The portal is composed of a dodecamer of UL6 molecules which form a ring-like struct

223 virus type 1 (HSV-1) portal is composed of a dodecamer of UL6 protein molecules whose incorporation i

224 The crystal structure of a dodecamer of Z from Lassa virus, presented here, illustr

225 ligomers ranging in size from dimers through dodecamers of 4 kDa monomeric Abeta have been resolved i

226 Higher resolution mapping using a set of dodecamers of overlapping sequences from the C-terminal

227 o three modifications were incorporated into dodecamers of RNA [AAGA GGG AUGAC] resulting in thermal

228 Dodecamers of RNA [CUACGGAAUCAU] were functionalized wit

229 DNA dodecamers of the alternating d(CG).d(CG) sequence with

230 assembly, particularly favoring formation of dodecamers of three laterally associated end-on tetramer

231 rmation of a set of 30 octamer, decamer, and dodecamer oligomers for which high-resolution crystal st

232 roscopy using a series of self-complementary dodecamer oligonucleotides that contain the sequence mot

233 The other contains dodecamer oligosaccharides at these same sites.

234 tions on lectin activity, incubation of SP-D dodecamers or murine lavage with peroxynitrite decreased

235 0-50 nm diameter, consisting of eight hetero-dodecamers) or three small rings (10-20 nm diameter, eac

236 al arrangement to form a dodecamer, and five dodecamers pack together to form an annular pore.

237 ndividuals responded to the atypically large dodecamer peptide (169)EECDSELEIKRY(180), which encompas

238 CD1c presented an N-acyl glycine dodecamer peptide (lipo-12) to human T cells, and the re

239 n and yellow fluorescent proteins fused by a dodecamer peptide encompassing a natural cleavage site.

240 The dodecamer peptide SLCHDSVIGWEC, named E12, was selected

241 ound more stably to HLA-B*18:01 than did the dodecamer peptide, whereas, conversely, HLA-B*44:03 boun

242 e binding pocket that accommodates an active dodecamer peptide.

243 otif demonstrated that nonamer, decamer, and dodecamer peptides containing the sequence KCDICTDEY (re

244 The low-affinity, tetramer-negative, dodecamer-positive T cells showed comparable effector cy

245 The dodecamer possesses the normal vector plot and inclinati

246 We discovered that Abeta42 hexamers and dodecamers quickly become the dominant oligomers after p

247 The solution structure of the RNA dodecamer r(CGCAAAUUUGCG)2has been determined using NMR

248 y element in Vbeta6.7 should be considered a dodecamer rather than a decamer and that it confers stro

249 rmamidopyrimidine lesions reduce the T(M) of dodecamers relative to their unmodified nucleotide count

250 s identified to date contain expansions of a dodecamer repeat located upstream of the transcription s

251 genotyping assay capable of detecting single dodecamer repeat unit differences on an automated DNA se

252 We furthermore suggest that expansion of a dodecamer repeat, which we predict to have very high fle

253 ompleted within 1 min, whereas activation of dodecamers required 1 h for completion.

254 are either exposed or sandwiched inside the dodecamer, respectively.

255 tudies show that the minor groove in an AATT dodecamer responds to local sodium ion positions and is

256 spectroscopy of the modified Dickerson-Drew dodecamer revealed that the conformation of the duplexes

257 and of a single dU(8) in the Dickerson-Drew dodecamer revealed that the modifications are essentiall

258 Electron microscopy of this dodecamer reveals a prolate structure with the protease

259 forms tetradecamers in solution, unlike the dodecamers seen in HslV.

260 xpectedly we found that recombinant rat SP-D dodecamers selectively induce the biosynthesis of collag

261 e synthetic ODNs based on the Dickerson Drew dodecamer sequence (CGCGAAT*T*CGCG) were examined where

262 The dodecamer sequence corresponds to the section of a site-

263 arcin and ricin, requires a nearly universal dodecamer sequence that folds into a G-bulged cross-stra

264 terminal His-tag on PrxIII markedly enhances dodecamer stability, particularly apparent in its oxidis

265 In the presence of divalent metal ions, the dodecamers "stack" along their six-fold axis of symmetry

266 The dodecamer structure of TmPep1050 also reveals that a par

267 p1050 of Thermotoga maritima, along with the dodecamer structure.

268 eplacement with the corresponding unmodified dodecamer structure.

269 Dodecamer structures are derived from crystals of [d(CGC

270 The dodecamer sugar is a consensus sequence incorporating th

271 limits would include the outermost repeated dodecamers suggested as arm recognition sites by S. J. S

272 similar to the outer surface of the soluble dodecamer, suggesting that the VacA surface in contact w

273 nits are required to form an alpha(6)beta(6) dodecamer that specifically catalyzes the decarboxylatio

274 Z3dU was >5 A, which indicated that in this dodecamer the Z3dU amino group did not participate in a

275 A X-ray structure of a double-stranded B-DNA dodecamer (the Dickerson Dodecamer, DDD, [d(CGCGAATTCGCG

276 rther associate into hexamers, octamers, and dodecamers: the hexamers are trimers of dimers; the octa

277 that denatured substrates coated the HSP18.1 dodecamers to form expanded complexes.

278 e TnrA dimer and causing an unprecedented GS dodecamer-to-tetradecamer conversion, which concomitantl

279 dynamics study of 21 Casiopeinas with a DNA dodecamer using 10 mus of simulation time for each compo

280 en [Pt(ammine)(cyclohexylamine)]2+ and a DNA dodecamer, using the same sequence as previously reporte

281 ormation of the cytosolic domain in the FtsH dodecamer visualized by negative stain TEM suggests a la

282 Titration calorimetry on the Dickerson dodecamer was also done, with results that were in agree

283 The adenine in each A.T basepair of the dodecamer was labeled with 15N at the N6 position, and t

284 stribution of conserved surfaces in the PdxS dodecamer was used to predict a docking site for the glu

285 ion crystal structures of the Dickerson-Drew dodecamer was used to re-evaluate the deoxyribose pseudo

286 cent crystal and NMR structures of the EcoRI dodecamer, where an overall bend of seven degrees is dis

287 A X-ray structure of the DDD (Dickerson-Drew dodecamer), which has been covalently modified by the te

288 ecules within the hydration shell of a B-DNA dodecamer, which are of interest for many of its biochem

289 n induces the formation of fully active FtsH dodecamers, which consist of two FtsH hexamers in a sing

290 er with 20 chains (11.1 ELISA units) and the dodecamer with 10 chains (9.52 ELISA units).

291 a reversible equilibrium between trimer and dodecamer with an equilibrium constant of approximately

292 r in solution, upon binding DNA, BAF forms a dodecamer with DNA bound at multiple discrete sites in t

293 ther known proteasome activator, PafE formed dodecamers with 12-fold symmetry, which required a glyci

294 rivatives yielded oligoadenylates as long as dodecamers with a regioselectivity for 3',5'-phosphodies

295 r dynamics simulations of double-helical DNA dodecamers with and without a single abasic (tetrahydrof

296 s to laterally aggregate and intertwine into dodecamers with elongated, twisted conformations contain

297 LKK) did not interfere with the secretion of dodecamers with lectin activity.

298 21-25 A revealed that all four isoforms were dodecamers with similar but highly unusual architecture.

299 The holoenzyme of PCC is an alpha(6)beta(6) dodecamer, with a molecular mass of 750 kDa.

300 The macrocycles range from a trimer to a dodecamer, with ring sizes from 24 to 114 atoms, and are