ライフサイエンスコーパス: domain

1 domain and carrier transport in the spatial domain.

2 Another motif, DPHK, is in the DNA-binding domain.

3 -phosphate (cyclic FMN) through an FMN lyase domain.

4 domain but lacks the intracellular signaling domain.

5 but requires an intact ubiquitin-like (UBL) domain.

6 rminal domain and an unstructured N-terminal domain.

7 g UBA(Cez) as a functional ubiquitin-binding domain.

8 ing nuclease activity in the C-terminal Crn2 domain.

9 (MAGE) proteins all contain a MAGE homology domain.

10 vels of random exploration in the conceptual domain.

11 a-helices of the dimeric Atg16L1 coiled-coil domain.

12 the loop region of CFTR's membrane-spanning domain.

13 location of temporal attention in the visual domain.

14 ncoded in the magnetization of ferromagnetic domains.

15 cale conformational changes between LIV-BPSS domains.

16 ocytes can extend across neuronal functional domains.

17 nctional differences in the GTPase and stalk domains.

18 Tolls demarcate a map of brain anatomical domains.

19 dimerization and activation of the catalytic domains.

20 ric molecule containing tail, body, and head domains.

21 strategy for assigning functions to protein domains.

22 lays a fundamental role in stabilizing cbEGF domains.

23 ocieties, over history, and among behavioral domains.

24 iphosphate-dependent enzyme comprising three domains.

25 tions across fluids, brain imaging and other domains.

26 ransmembrane (TM) domain and contains six TM domains.

27 , which detects nanodomains as well as large domains.

28 which both contain the described PRR and WH2 domains.

29 wisted in the space-frequency and space-time domains.

30 riptive analyses of the complementary survey domains.

31 ory domain (CTD); a carotenoid spans the two domains.

32 onal analysis of 4 variants in transmembrane domains 1 or 2 (p.Ile246Thr, p.Pro252Leu, p.Ile288Ser, p

33 s; this association required the GAP-related domain (1004-1237 aa) of IQGAP1.

34 ic variants clustered in the C3, C6, and C10 domains (18 of 22, 82%, P<0.001 versus Genome Aggregatio

35 rotein 53 (TP53; 18.7%), AT-rich interaction domain 1A (ARID1A) (13%), albumin (11.4%), apolipoprotei

36 l paralogs coiled-helix-coiled-helix (CHCHD) domain 2 (C2) and CHCHD10 (C10) were recently identified

37 ic acid/aspartic acid-rich carboxyl-terminal domain 2 (CITED2) as a critical intrinsic negative regul

38 at ArfGAP with dual pleckstrin homology (PH) domains 2 (ADAP2), gamma-interferon-inducible lysosome/e

39 similar correlations with broad personality domains(3).

40 ly expressed in normal and neoplastic cells) domains(7), and WDR41 is a beta-propeller protein that b

41 ellular prion protein (PrP(C)) comprises two domains: a globular C-terminal domain and an unstructure

42 r, containing two transactivation functional domains, AF-1 and AF-2.

43 orrelates associated with the other language domains align with existing models on the ventral and do

44 AD domain analysis showed the AD domain of both ADADs was l

45 -activated ribonuclease activity in the Csx1 domain and a potent cA4 ring nuclease activity in the C-

46 ding and refolding of a titin immunoglobulin domain and alpha-actinin spectrin repeats.

47 comprises two domains: a globular C-terminal domain and an unstructured N-terminal domain.

48 rge generation and recombination in the time domain and carrier transport in the spatial domain.

49 d two adjacent sites buried in the cytosolic domain and chelated by conserved residues from CTD and t

50 riants excludes the first transmembrane (TM) domain and contains six TM domains.

51 STEAP1 lacks an intracellular NADPH-binding domain and does not exhibit cellular ferric reductase ac

52 roteolytic activity of Ddi1 requires the HDD domain and is stimulated by the UBL domain, which mediat

53 N-terminal four-helix bundle (4HB) "killer" domain and neighboring first brace helix of human MLKL w

54 utions in the core alpha/beta hydrolase-fold domain and the hairpin, exhibited hormone-independent in

55 location to the detergent-resistant membrane domain and to inhibit CD40-induced phosphorylation of th

56 The MDMX acidic domain and zinc finger are necessary and sufficient for

57 ns are entirely independent of the catalytic domains and are mediated by ionic interactions with the

58 ture is that it allows for training on small domains and evaluation on arbitrarily-sized inputs, incl

59 olution-state shifts for the RRM2,3 isolated domains and homology modeling.

60 Study completed surveys assessing 10 symptom domains and SF-36 HRQOL summary scores.

61 mmunication via their apical and basolateral domains and suggest that defective ESCRT function may co

62 Heart rate variability (time and frequency domain) and arrhythmias were compared by 24h-Holter, bef

63 a range of mini-spidroins with both terminal domains, and characterize their response to a number of

64 change occurred in which low-density liquid domains appeared and grew on time scales between 20 nano

65 ests mammalian lipins function with the same domain architecture as Tt Pah2.

66 bodies targeting the RSV G central conserved domain are protective in both prophylactic and postinfec

67 and G Ab responses against receptor-binding domain are significantly correlated to the disease sever

68 ecreases under mechanical stress (i.e. cbEGF domains are mechanosensitive).

69 he sizes of the non-backtracking single cell domains are most close to the sizes of compartments from

70 The globular domains are often omitted in recombinant spidroins, but

71 We find that the domains are regularly distributed along the filament at

72 structures, indicating that these asymmetric domain arrangements are not linked to negative cooperati

73 Cellular-based studies revealed the GR domain as being necessary and sufficient for SRBP1 cell-

74 ding results for the JH1, JH2, and JH2 V617F domains, as well as five crystal structures for JH2 comp

75 ies were at high risk of bias for index test domain because no reported thresholds were prespecified.

76 Deletion of Cav-1 scaffold domain binding (CSD) motif in EphB1 prevented EphB1 bind

77 The C-terminal BON domain binds anionic phospholipids through an extensive

78 ith liposomes revealed that the Aster-B GRAM domain binds to membranes in a cholesterol concentration

79 ibitory conformation in which a large linker domain blocks activation and substrate access.

80 oreover, we also present a structure of this domain bound to the substrate diC8-PI(3,4,5)P(3), provid

81 and retains the extracellular ligand binding domain but lacks the intracellular signaling domain.

82 ) can indeed fulfill this role as regulatory domain by binding various ubiquitin chain types.

83 (SMD) simulations, we demonstrate that cbEGF domain calcium binding decreases under mechanical stress

84 d UBE2K-Ub(2) complexes and show how the UBA domain can alter the position of a polyubiquitin chain a

85 r results demonstrate that distinct membrane domains can integrate a common signal with specific mach

86 Moreover, the found domains clearly segregate in the gene density and correl

87 the final PICU core outcome set: four Global Domains (Cognitive, Emotional, Physical, and Overall Hea

88 avirus G(N) proteins, they all share similar domain connectivity that resembles glycoproteins from un

89 and Type II-C Cas9s, likely due to Cas9 HNH domain conservation.

90 forms a complex with DALR anticodon binding domain containing 3 (DALRD3) protein to recognize partic

91 CEP104 and CSPP1, we identified coiled-coil domain containing 66 (CCDC66) and TOG array regulator of

92 f these control activities depend upon PASTA-domain containing eukaryotic-like serine/threonine prote

93 orce, and these are confined to the filament domain containing myosin binding protein-C, the "C-zone.

94 Arrestin domain-containing 3 (Arrdc3) is a member of the alpha-ar

95 s of its regulation of the NLR family, pyrin domain-containing 3 (NLRP3) inflammasome.

96 and prime the nod-like receptor family pyrin domain-containing 3 inflammasome in naive neutrophils an

97 al maintenance of chromosomes flexible hinge domain-containing protein 1 (SMCHD1) has been implicated

98 ,023 short-read sequences matching with a GH domain-containing protein were located outside the domai

99 The gene encoding Sac2/INPP5F, another Sac domain-containing protein, is located within a PD risk l

100 We find that the SNF2 domain couples substrate specificity to an ATPase step e

101 interfacial site between TMD and C-terminal domain (CTD) that modulates the Zn(2+) transport activit

102 RNA Pol II) contains a disordered C-terminal domain (CTD) whose length enigmatically correlates with

103 tor domain (NTD) and a C-terminal regulatory domain (CTD); a carotenoid spans the two domains.

104 Missense mutations in the p53 DNA-binding domain (DBD) contribute to half of new cancer cases annu

105 e sensor, which interacts with a closed pore domain directly via two interfaces and indirectly via an

106 Pathogenic domain disruptions can result from chromosomal rearrange

107 oordinating cysteines within the DNA-binding domain, distal to the zinc-binding site.

108 conclude that variants investigated in this domain do not cause disease, with the exception of p.A35

109 ned a peptide encompassing the extracellular domains (ECD) of PLP.

110 nfullerene acceptors (NFAs) with crystalline domains enable high-performance bulk heterojunction (BHJ

111 The HIF prolyl hydroxylase domain enzymes (PHDs) are Fe(II)- and 2-oxoglutarate-dep

112 as unlocked unprecedented success in various domains, especially using images, text, and speech.

113 rial in the wide pressure-volume-temperature domain even if its typical form with constant scaling ex

114 2 zinc finger is the most common DNA-binding domain expanding in metazoans since the fungi human spli

115 ds is often accomplished by researchers with domain expertise but without formal training in software

116 ediction show that CTM provides an important domain for interaction of HOXA1 proteins with PBX.

117 The temperature dependence of ordered domain formation was measured using Forster resonance en

118 Deleting the GAF domain from PtsP makes cells "blind" to the cellular nit

119 report results of parental surveys of these domains from the second Newborn Sequencing in Genomic Me

120 ng protein-C, the "C-zone." Myosin motors in domains further from the filament midpoint are likely to

121 g recall supports the growing consensus of a domain-general cognitive map.

122 ehension, providing further evidence for the domain generality of semantic processing in the brain.

123 It also revealed that the head domain glycans affect N1 stability more than N2, suggest

124 The Src homology 2 (SH2) domain has a highly conserved architecture that recogniz

125 The IgG Fc domain has the capacity to interact with diverse types o

126 nded loop in the C-terminal receptor-binding domain (HC) of BoNT/B (HC/B) has been proposed to also c

127 on mutations in the flexible helical hairpin domain HP2 and applied linear free energy relationship a

128 Overexpression of human TET catalytic domains (hTETCDs) from the TET family members, especiall

129 of COVID-19 with high anti-receptor binding domain IgG titer convalescent plasma is efficacious in e

130 ucted to display ten dengue envelope protein domain III (ED3)-targeting aptamers into a two-dimension

131 uncate its C-terminal cytoplasmic regulatory domain impair NHE6 activity and endosomal function are p

132 he constitutively active NOTCH intracellular domain in CD11c-expressing cells.

133 o characterize structural features of the PH domain in its autoinhibited and activated states.

134 plex reveals a crucial role of the insertion domain in MvcA in substrate recognition.

135 th high affinity through its HMG DNA-binding domain in vitro.

136 n other conditions, the formation of ordered domains in a SM and cholesterol-rich leaflet can be supp

137 ortance of these specialized plasma membrane domains in cellular feedback via the Hippo pathway.

138 trodes helps eliminate the existence of twin domains in Cr(2)O(3) films, therefore significantly redu

139 Folding of individual domains in large proteins during translation helps to av

140 ur annotation of the chromatin compartmental domains in single cells Hi-C matrices.

141 el, in which kinesin-5 tails stabilize motor domains in the microtubule-bound state by slowing ATP-bi

142 gle-exponential decay in the spatial Fourier domain, in excellent agreement with theoretical predicti

143 ity, diversity, and inclusion across several domains including ethnicity and gender.

144 racterized by significant changes in several domains, including brain structure and function, puberty

145 (T788/T789) in the integrin beta cytoplasmic domain increases integrin activity.

146 nment strategy for GPU architectures that is domain independent, supporting alignment of sequences fr

147 kingly, Ubqln4 engages the J proteins in a J-domain-independent manner, in contrast to the previously

148 is the first technology to enable saturated domain insertion profiling.

149 addition to sites corresponding to heme-CPR domain interactions at the dimeric interface.

150 on comprising three pleckstrin homology (PH) domains interacts with the N-terminal region comprising

151 In all three proteins, this non-domain "interkinase region" has low sequence complexity,

152 e integrity of the CCHC motifs in the Gag NC domain is dispensable for Alix-mediated rescue of virus

153 we found no evidence that a single receptor domain is responsible for the Fls3-sustained reactive ox

154 ated proteins showed that mobility in plaque domains is affected by mobility of the Cx proteins.

155 ition and quality control of misfolded C-Pro domains is mediated by recognizing stalled assembly of t

156 ically unstructured N-terminal translocation domain (IUTD) of the endonuclease bacteriocin ColE9 is i

157 region of SCN5A in the S4 voltage sensor of domain IV and stably integrated the library into HEK293T

158 chaeal chromatin, on both the organismal and domain level.

159 A Cas2-like domain likely helps to position Bax1 at the forked DNA a

160 RAS and CRAF, and we provide high-resolution domain mapping on this and other protein-interacting pai

161 , the LRR of FliI, but not its gelsolin-like domains, mediated association with cdc42, R-ras, and IQG

162 e comprehensively reveal the nature of SARAH domain-mediated complex formation and provide mechanisti

163 provide mechanistic insights into how SARAH domain-mediated interactions influence Hippo pathway act

164 GAIN domain-mediated self-cleavage is constitutive and produc

165 ion helps to avoid otherwise prevalent inter-domain misfolding.

166 te was especially stable, had relatively low domain mobility, and associated the histidine substrate

167 with a spatial resolution ca. 5 nm to reveal domain morphology and distribution.

168 ross the prostate cancer biomedical research domain, Movember conducted a landscape analysis with the

169 Human tumors with exonuclease domain mutations in the gene encoding DNA polymerase eps

170 odular, consisting of an N-terminal effector domain (NTD) and a C-terminal regulatory domain (CTD); a

171 D) and those directed against the N-terminal domain (NTD), indicating that both of these regions at t

172 This spectral-domain OCT analysis identified various patterns of macul

173 nal pigment epithelium (RPE) in 836 spectral-domain OCT slices from 44 eyes of 39 patients.

174 Fibrosis was categorized using spectral-domain OCT with respect to retinal pigment epithelium (R

175 t macular 3- x 3-mm OCTA scans with spectral domain OCTA.

176 eport a crystal structure of the DNA-binding domain of a model ASO-binding protein PC4, in complex wi

177 The NTD-core domain of Aedes aegypti Nbr adopts a HEAT-like repeat sc

178 n determining the activity of the C-terminal domain of bacterial Enzyme I (EIC).

179 AD domain analysis showed the AD domain of both ADADs was likely catalytically inactive,

180 ix and develops contacts with the C-terminal domain of CaM in about 2 ms.

181 -protein contact with the cytoplasmic C-tail domain of Canx.

182 kyrin repeat motifs in the substrate binding domain of cpSRP43 drives its activation.

183 It is believed that the transmembrane (TM) domain of EphA2 adopts two alternate conformations in th

184 scover that the C-terminal substrate-binding domain of FBXL5 contains a redox-sensitive [2Fe-2S] clus

185 ss gradient corresponds to a Wnt5a-dependent domain of fibronectin expression, raising the possibilit

186 -containing protein were located outside the domain of interest.

187 rious archaeal organisms across the archaeal domain of life show surprising levels of diversity at ma

188 phage display library based on the variable domain of new antigen receptor (VNAR) was used for in vi

189 ng of PIP(3) to the pleckstrin homology (PH) domain of P-Rex1 is required for its activation in cells

190 binds directly to the coiled-coil 1B (CC1B) domain of p150(Glued), thus explaining why H2 is necessa

191 ) subunit, p67(phox), and to the RAC-binding domain of p21-activated kinase, consistent with our earl

192 y, we found that expression of the catalytic domain of PDE3A in cancer cells lacking PDE3A is suffici

193 both of which are central to the burgeoning domain of stereodivergent catalysis.

194 aled a structural similarity to the scaffold domain of TBK1, suggesting an evolutionary similarity be

195 We identify that a fusion of the catalytic domain of TET1 to dCas9 targeted to the CDKL5 promoter u

196 and heterozygous variants in the N-terminal domain of the A isoform of FHF2 (FHF2A).

197 e HSC emergence predominantly in the ventral domain of the dorsal aorta.

198 ephaly, specifically interacts with the TRFH domain of the telomere binding protein TRF2.

199 to TRIF, we identified the STING-interacting domain of TRIF and generated STING-noninteracting mutant

200 ucible homo-interaction of the intracellular domain of TrkB in the cytosol or on the plasma membrane

201 s of mutant pre-ribosomes lacking the tunnel domain of uL4 reveal a misassembled NPET, including an a

202 The binding domains of A. phagocytophilum adhesins A. phagocytophilu

203 The hinge domains of cohesin adopt an "open washer" conformation a

204 This approach enumerates five domains of evaluation-(1) medical history, (2) physical

205 oscopy (EM) data resolving the EC1 and EC1+2 domains of human CDHR3 complexed with viral isolate C15a

206 rs has been identified in organisms from all domains of life.

207 canonical interactions between the globular domains of M/R and DNA, we observe transient interaction

208 a composite binding site bridging over three domains of one capsid protein (CP) monomer.

209 a spontaneously broken symmetry in distinct domains of opposite polar orientation.

210 asiological battery, to identify fundamental domains of post-stroke aphasia.

211 ion encoded regions of the phosphatase or C2 domains of PTEN.

212 F2 to properly orient the flavin and capping domains of SDHA.

213 scopy on the light, oxygen, or voltage (LOV) domains of the blue light receptors aureochrome and phot

214 es from the emotional, mobility, and reading domains of the Impact of Visual Impairment (IVI) questio

215 ension buffer by reversibly unfolding repeat domains of the spectrin tetramers to release excess mech

216 the intrinsically disordered SH4 and Unique domains of the Src family kinase Hck.

217 Selected domains of these proteins were produced recombinantly in

218 an opening of the complex into two separate domains, one of which acts as a quencher for the light-h

219 a series of patients with ECE using spectral-domain optical coherence tomography (SD-OCT) imaging and

220 ity can be ameliorated by targeting specific domain or proteostatic pathway of mHTT, providing novel

221 cognizing stalled assembly of triple-helical domains or by direct engagement of the C-Pro itself.

222 ylinositol 4,5-bisphosphate (PIP(2)) binding domains, or the entire C terminus, was without effect on

223 eric PfISN1 reveal complex rearrangements of domain organization tightly associated with catalysis.

224 How emotional domains overlap within patients and their caregivers and

225 Relative to the spatial domain, participants showed reduced levels of uncertaint

226 ixtures frequently occur in data across many domains, particularly in the fields of environmental and

227 In 2007 only the association with physical domain (physical functioning, role limitations caused by

228 Two-pore-domain potassium channels (K(2P)) are the major determin

229 , the molecular mechanisms of multivalent WW domain-PPXY assemblies are still poorly understood.

230 g conformers may be common in multivalent WW domain-PPXY interactions to promote the adaptability and

231 omote the adaptability and versatility of WW domain-PPXY mediated cellular processes.

232 if defines an evolutionarily ancient protein domain present in several enzymes that hydrolyze cyclic

233 the C terminus and downstream of the WH2-PRR domain produces a long (SHTN1L or shootin1b) and a short

234 1A (encoding HIF-1alpha) and endothelial PAS domain protein 1 (EPAS1 encoding HIF-2alpha), inhibited

235 her, these results illustrate how this multi-domain protein's ability to accommodate and yet discrimi

236 vated protein kinase (MAPK) activating death domain protein, regulates various cellular functions, su

237 The FinO-domain-protein ProQ is an RNA-binding protein that has b

238 those directed against the receptor-binding domain (RBD) and those directed against the N-terminal d

239 The receptor-binding domain (RBD) is immunodominant and the target of 90% of

240 ctrodes was pre-coated with receptor binding domain (RBD) of SARS-CoV-2 spike protein, and subsequent

241 IgA antibodies to the spike receptor binding domain (RBD), S1+S2, nucleocapsid, and ORF6 to ORF10 of

242 NAs, mediated by three N-terminal Repression Domains (RDs), which are unique to Pumilio orthologs.

243 In three experiments using word stimuli, domain-relevant and atypical conceptual access for the c

244 Currently, the mechanism and domains required for channel formation have yet to be el

245 the N-terminal cysteine-rich and fibronectin domains reside at the central intersection.

246 r is anchored in a surface groove of the TTD domain, resulting in creation of a coupled TTD-PHD modul

247 arameters, and GSRS-IBS total score and pain domain (rho = 0.40, p < 0.001, and rho = 0.38, p < 0.001

248 ation of the target cytosine bypass the SNF2 domain's requirement for hemimethylation.

249 Between-group difference in psychological domain score was 5.6 points (95% CI, -1.13 to 12.3; P =

250 Visual acuity, spectral-domain (SD) OCT findings, injection details, and the dev

251 longitudinal assessment of monthly spectral-domain (SD) OCT scans to determine MA prevalence, incide

252 embling the S-layer-interacting FlaF soluble domain (sFlaF).

253 While biophysical studies of single WW domain-single PPXY motif complexes abound in the literat

254 ed as a test set; the remainder were used as domain-specific training data.

255 ases and present the narrative findings in 4 domains: stakeholder groups, net coverage and utilizatio

256 ntributing factor to impairment in cognitive domains such as memory and perceptual reasoning, and act

257 Domain swap chimeras also revealed previously unknown fu

258 compartments(1) and topologically associated domains (TADs)(2,3) consisting of chromatin loops(4).

259 The strong associations across the domains tapped by real-time monitoring suggest that futu

260 We describe the emergence of a protein domain that confers the capability of interacting with b

261 The C-terminus of UNC80 contains a domain that interacts with UNC79 and overcomes a soma-re

262 reviously identified groove in the EnvC LytM domain that is here found to be occluded by a "restraini

263 embrane through its pleckstrin homology (PH) domain that recognizes phosphatidylinositol 3,4,5-trisph

264 Spc110 domains that are required for SPB localization and toxic

265 t at 4-nm intervals and we can determine the domains that associate with features of the filament, su

266 DNA polymerase beta has two DNA-binding domains that interact with the opposite sides of short D

267 y design and, more broadly, other scientific domains that involve time-intensive experiments and mult

268 have been attributed to its main structural domains, the kringles, and have been proposed to be medi

269 nd GMP at the canonical sites of the Bateman domains, the latter in a so far unknown coordination mod

270 ase involve movements of the bulky transport domain through the lipid bilayer.

271 organization into topologically associating domains, thus highlighting the ability of our approach t

272 ghly conserved primary site in transmembrane domain (TMD) housing the Zn(2+) substrate; an interfacia

273 we report the primate-specific proline-rich domain to be dispensable for both HSP90 interaction and

274 Bax1 at the forked DNA allowing the nuclease domain to incise one arm of the fork.

275 we observed our virulence-associated CdiA-CT domain to promote toxicity against mammalian cells in cu

276 ters, allowing all four consensus functional domains to be linked.

277 itectural and logistical problem for the two domains to interact with their respective DNA termini.

278 varying from fully aggregated over graphitic domains to intercalated assemblies with polymer bilayers

279 2020, using a spike protein receptor binding domain total antibody chemiluminescence assay (100% sens

280 y originate from within the archaea in a two-domains tree when due consideration is given to the fit

281 ast, we found two residues in the C-terminal domain, tyrosine 351 and glutamate 355, that influence p

282 tically cleaved to release the extracellular domain, was endocytosed by podocytes to induce apoptosis

283 For each domain, we describe the current status of target establi

284 Despite the similarity in their enzymatic domain, we found that ULK1 and ULK2 have major differenc

285 N peripheral axon extension into the sensory domain, we used a genetic sparse labeling approach to tr

286 ts whose lesions were located in the Rho-GAP domain were deficient for Rho-GAP activity and for suppr

287 % mean scores across AGREE II and AGREE-REX domains were calculated for each guideline.

288 A PRO hypothesis and relevant PRO domains were specified in 36 (51%) RCTs.

289 yption advances can also be applied to other domains where large-scale statistical analyses over encr

290 nance (LMR) could be observed in the optical domain, where electrical properties of the film allowed

291 two intercalated rings of C-type lectin-like domains, where the N-terminal cysteine-rich and fibronec

292 The activity of DNGR-1 maps to its signaling domain, which activates SYK and NADPH oxidase to cause p

293 the HDD domain and is stimulated by the UBL domain, which mediates high-affinity interaction with th

294 ecause of its N-terminal Zalpha1 and Zalpha2 domains, which bind to nucleic acids in the Z-conformati

295 The vortices undergo a transition to the a-domain with in-plane polarization under external compres

296 ovies into adjacent spatiotemporal frequency domains with equal stimulus power, while the asymmetric

297 The most-aligned words were from semantic domains with high internal structure (number, quantity a

298 as possible to detect movements <1 nm of the domains with respect to each other.

299 sociated the histidine substrate and docking domains with the kinase core, thus preventing catalytic

300 ng five associated with the Chief Roi Mata's Domain World Heritage Area, and analyzed them in conjunc