ライフサイエンスコーパス: domain structure

1 mutants, we elucidated a new MLK4 catalytic domain structure.

2 MnO3/Nb:SrTiO3 (001) films showing twin-like domain structure.

3 nker region is not extended but folds into a domain structure.

4 Aux/IAA interactions have confirmed the PB1 domain structure.

5 n Top1 share a common reaction mechanism and domain structure.

6 monofunctional proteins of similar size and domain structure.

7 data have not revealed a common, underlying domain structure.

8 ting the importance of maintenance of proper domain structure.

9 isin-like proteases, and it contains a novel domain structure.

10 rst thermal unfolding temperature of the mAb domain structure.

11 y is strongly modified by the STO tetragonal domain structure.

12 ned PbZr(0.2)Ti(0.8)O(3) with a hierarchical domain structure.

13 tion of GAGs and enables modeling of the GAG domain structure.

14 e two domains leading to collapse of the two-domain structure.

15 qlH, a RecQ-like helicase with a distinctive domain structure.

16 ng domain exhibits a dual Per-Arnt-Sim (PAS) domain structure.

17 dimer creates an amphiphilic membrane-anchor domain structure.

18 self-cleavage or ligation via a specific two-domain structure.

19 synthase genes that retain the ancestral tri-domain structure.

20 and temperatures and with different internal domain structure.

21 TopBP1, revealing an unexpected triple-BRCT domain structure.

22 by the overall stabilization of the helicase domain structure.

23 le, whereas the C-terminal half has a single domain structure.

24 variants is also displayed on the protein's domain structure.

25 ls spontaneously undergo twinning to a multi-domain structure.

26 de the first evidence-based model of IF head domain structure.

27 to have significant destabilizing effects on domain structure.

28 s congruent with the enzyme's mosaic protein domain structure.

29 leotidyl cyclases disrupt the normal helical domain structure.

30 or H3K36 and H3K27 methylation in regulating domain structure.

31 involve founder 'p-loop' and 'winged helix' domain structures.

32 in the loop regions compared with other TIR domain structures.

33 distribution, and temperature dependence of domain structures.

34 t-manually curated classification of protein domain structures.

35 letion mutants, based on models of the known domain structures.

36 leads to the collapse of conserved loop and domain structures.

37 to control others by reconfiguring magnetic domain structures.

38 n architectures of coexisting c/a and a1 /a2 domain structures.

39 ications are unable to map titin variants to domain structures.

40 uously and they are also embedded in diverse domain structures.

41 xation mechanisms, electrical properties and domain structures.

42 leads to novel defect-stabilized symmetrical domain structures.

43 overall fold of MAL compared with other TIR domain structures: A sequence motif comprising a beta-st

44 Once established, domain structure abrogates the need for precise initiati

45 The planar domain structure accompanies abundant charged domain wal

46 Here, we aimed to stabilize the Kunitz domain structure against proteolysis through disulfide e

47 Electric-field control over domain structure allows the photovoltaic effect to be re

48 lly structured and lacked the correct domain-domain structure and active-site cleft formed in the nat

49 es that grapevine GH3-1 has a highly similar domain structure and also undergoes a large conformation

50 urfactant protein (SP-A), which has the same domain structure and architecture as MBL but lacks any i

51 ttice and propagate through to the nanoscale domain structure and assembly, leading to microscale mor

52 ow temporal sequence variations affect the P domain structure and contribute to epochal evolution, we

53 udied the effects of phosphorylation on head domain structure and demonstrate that phosphorylation dr

54 gnore spatial features in Hi-C data, such as domain structure and distance dependence.

55 ide for the first time information about the domain structure and DNA-binding activity of D5, the pox

56 electric are substantially determined by its domain structure and domain wall dynamics at mesoscopic

57 and an evolutionary relationship between RNA domain structure and essential replicative functions.

58 ucing environment as well as PtdIns5P on the domain structure and function are unknown.

59 ver time, resulting in subtle differences in domain structure and function.

60 efore a powerful tool for the study of mucin domain structure and function.

61 They share a complex domain structure and have numerous binding partners in E

62 espite this research, the true ferroelectric domain structure and its relationship with structural do

63 d human mutant LTBP-2 proteins retain normal domain structure and keep the fibrillin-1-binding site i

64 Using the domain structure and multiple screens, we identify a dom

65 h the mammalian TBL1, which shares a similar domain structure and performs a parallel corepressor fun

66 Variations in apoA-I domain structure and physical properties exerted similar

67 findings with regard to L protein appendage domain structure and putative domain-domain interactions

68 these HIV-1 envelope proteins share the same domain structure and similar sequences, we performed mut

69 Magnetic domain structure and spin-dependent reflectivity measure

70 n DLBCL and reveal an unusual autoinhibitory domain structure and strategy for preventing unwarranted

71 re ligand binding induces alterations in PAS domain structure and subunit association that is relayed

72 le for cohesin in the global organization of domain structure and suggest that domains function to st

73 lyzed their phylogeny, protein topology, and domain structure and surveyed their expression and local

74 The modular domain structure and the functionality of the individual

75 ion method for understanding polycrystalline domain structure and transport in plastic crystals and o

76 layer thickness and judicious engineering of domain structures and ferroelectric-electrode interfaces

77 hourglass patterns in rates of appearance of domain structures and functions, functional diversity, a

78 We determine Pmt2- and Pmt3-MIR domain structures and identify two conserved mannose-bin

79 to be understood about switching in complex domain structures and in devices.

80 led significant differences in the local PDZ domain structures and in the global conformations compar

81 rovides annotations for over 235,000 protein domain structures and includes 25 million domain predict

82 The resource comprises over 300 000 domain structures and over 53 million protein domains cl

83 Analyses of the domain structures and properties of the interdomain inte

84 Phylogenies that describe the evolution of domain structures and proteomes were reconstructed from

85 Together with the individual domain structures and small-angle X-ray scattering, this

86 core that combines information from template domain structures and terminal and internal alignment ga

87 Despite similarities in sequence, domain structure, and biochemical activity, they play di

88 ilitate spatiotemporal control of alignment, domain structure, and birefringence.

89 gical mutations mapping in the NTD alter the domain structure, and decrease catalytic activity and st

90 e fields increase the pinning, stabilize the domain structure, and harden the magnet, until a point w

91 MscS homologs exhibit diverse topology and domain structure, and it has been proposed that the more

92 contribution of localization, glycosylation, domain structure, and the absence of substrate class I M

93 series of Cys/Gly mutant forms with aberrant domain structures, and as a double point-mutated probe (

94 cantly from previously described tandem BRCT domain structures, and presents two distinct sites for b

95 unexpected crystal structures, ferroelectric domain structures, and properties.

96 all potential barrier between the degenerate domain structures, and the large anisotropy of a and c d

97 Gene3D is a database of protein domain structure annotations for protein sequences.

98 Overall, roughly one-third of the outer domain structure appeared to be fixed in conformation, i

99 In mutants R202Q and T263M, effects on the A-domain structure are responsible for a reduced rate of t

100 dicted amino acid sequence indicated SfPER's domain structure as a CMCMC-type, consisting of a signal

101 The polar CheA, CheA(2), has the same domain structure as E. coli CheA and can phosphorylate a

102 onal paratopes with the 3D antibody variable domain structure as input.

103 of the open reading frame but share the same domain structures as in typical nuclear receptors: AF1,

104 kyrmion lattice and the stripe-like magnetic domain structures as well.

105 sion and thus to a drastic disruption of the domain structures at a much lower number of nanoparticle

106 sensor to map out layered antiferromagnetic domain structures at zero magnetic field as well as anti

107 wave is engineered by properly designing the domain structure based on the Huygens-Fresnel principle.

108 cture classification hierarchically clusters domain structures based on structure and/or sequence sim

109 orms into the less-symmetric parallel-stripe domain structure, before the onset of paraelectricity at

110 osynthetic pathway, minimally altering local domain structure but adversely impacting ABCC6 assembly

111 reveal the archetypal F1-F2-F3 trilobed FERM domain structure but show that the F3c subdomain orienta

112 ERManI and GMIA have similar catalytic domain structures, but each enzyme cleaves distinct resi

113 rimentally demonstrate that large and stable domain structure can be mediated by lipids in single-pha

114 The evolution of complex domain structure can be understood by the process of occ

115 k of comprehensive understanding of magnetic domain structures carrying remanence has, until now, pre

116 sNASP contains the domain structure characteristic of this family, which in

117 The unique domain structure characterized by a "split" SET domain,

118 Here, a new route to such effects involving domain-structure competition is demonstrated, which aris

119 e Spt6 C-terminal region reveal a tandem SH2 domain structure composed of two closely associated SH2

120 They have a unique three-domain structure, comprising a calcium-regulated N-termi

121 a superfamily II helicase with a distinctive domain structure, comprising an N-terminal NTPase domain

122 e demonstrated the destabilization of the A1 domain structure concomitantly results in a reduced inte

123 een predicted to have a conserved tripartite domain structure consisting of a largely alpha-helical c

124 ant ARABIDILLO-related proteins has a unique domain structure consisting of an F-box and leucine-rich

125 The E2 core has a compact, globular domain structure, consisting mostly of beta-strands and

126 The AHNAK2 PDZ domain structure contains a bound class III ligand pepti

127 , and even the de novo prediction of protein domain structures, contingent on the existence of a larg

128 tching (QPM) processes in a single nonlinear domain structure correct phase and group-velocity mismat

129 nker forms an integral part of the catalytic domain structure, covering a hydrophobic patch on the ca

130 of elementary functional loop sequences and domain structures defined at the fold superfamily level

131 ed for the refinement of the NMDA receptor M domain structure, demonstrate that this region can influ

132 d that biotype 3 MARTX toxin has an effector domain structure distinct from that of either biotype 1

133 nctions, thus showing that the NHR2 and NHR4 domain structures do not have irreplaceable functions co

134 of Nb ions in BFO films showed change in the domain structures due to doping induced change in lattic

135 ggesting that, despite their highly diverged domain structure, each receptor couples to a common repu

136 What to our knowledge is a novel domain structure emerges in which elemental nanodomains,

137 pinodal decomposition, forming compositional domain structures enriched in the immiscible element, an

138 The domain structure explains how the S components with larg

139 An electrically written domain structure formed by a biased tip, and visualized

140 tural rearrangement of more than half the 13-domain structure from a native to a compact induced form

141 ould be to systematically fit representative domain structures from a protein domain database into th

142 family, using all available kinase catalytic domain structures from any organism as structural templa

143 rance of homologous superfamilies of protein domain structures from CATH.

144 lar matrix proteins; provides new clues into domain structure, function, and pathogenesis for myocili

145 sly reported inactive and active EGFR kinase domain structures gave insight into the mechanism of HER

146 clinical significance, only the IRAK4 kinase domain structure has been determined among the four IRAK

147 stead larger grains containing single-vortex domain structures have very large remanences and high th

148 therapeutic value is limited by its complex domain structure, high cost of production, instability,

149 o electrically pattern non-volatile magnetic-domain structures hosting chiral edge states, with appli

150 Both proteins are similar in size and domain structure; however, despite the overall similarit

151 leads to large energy barriers resulting in domain structure, hysteresis and cracking.

152 at compartmental domains are responsible for domain structure in all eukaryotes, with CTCF playing an

153 Directed self-assembly (DSA) of the domain structure in block copolymer (BCP) thin films is

154 ting that spatial proximity derived from the domain structure in chromatin plays an important role in

155 e a-axis and c-axis enabled by the twin-like domain structure in DyMnO3 films, despite the polarizati

156 ults demonstrate smaller size highly ordered domain structure in grain-oriented specimen relative to

157 ate NMR data were used to further refine the domain structure in phospholipid bilayers.

158 the present study, we investigated both, the domain structure in pure DPPC monolayers as well as in l

159 achieved by the creation of an adaptive nano-domain structure in these perovskite films via phase eng

160 d canonical SMC proteins share a common five-domain structure in which globular N- and C-terminal reg

161 visualization and reconstruction of magnetic domain structures in a 3D curved magnetic thin films wit

162 werful and effective way to characterize the domain structures in alpha-Mo(2) C, which will facilitat

163 parameter for enabling the understanding of domain structures in CuMnAs imaged using x-ray magnetic

164 advances allow detailed analysis of magnetic domain structures in iron particles as a function of gra

165 Protein domain structures in proteomes are highly conserved and

166 e have analyzed the existing database of PDZ domain structures in the context of a specificity tree b

167 Only compact domain structures in this library fit well to the scatte

168 falls reveal how ancient loops are shared by domain structures in two initial waves of functional inn

169 des a hierarchical classification of protein domain structures including a sub-classification of supe

170 n-ribosomal peptide synthetases with unusual domain structures, including several split modules and a

171 Here we discuss what is known about FinO-domain structures, including the recently solved Escheri

172 Fitting high-resolution KIX domain structures into the SAXS-derived envelopes sugges

173 However, current approaches that map the domain structure involve either spatially resolved but p

174 Previously unobserved in a beta-grasp domain structure is a 48-residue helical hairpin insert

175 e size and strain relaxation on the magnetic domain structure is also discussed.

176 The plexin domain structure is conserved throughout all clades; in

177 activity in vitro and that proper N-terminal domain structure is critical for activity of the full-le

178 cess of in vitro assembly, we show that head domain structure is dynamic, changing as a result of fil

179 Our results show that the TgMyoA domain structure is more similar to other myosins than p

180 To visualize and prepare a well-defined domain structure is of key importance.

181 nly partially, indicating that the whole tri-domain structure is required for such capability in full

182 in, Cin1 (cryptococcal intersectin 1), whose domain structure is similar to that of the human endocyt

183 The distribution of the domain structures is likely governed by the action of gl

184 ecDNA is packaged into chromatin with intact domain structure, it lacks higher-order compaction that

185 Through a combination of domain structure knowledge and intermolecular and concen

186 ferroelectric response and the corresponding domain structures, magnetic behaviors and spin dynamics

187 tional materials that benefit from nanoscale domain structure manipulation.

188 onstrates similar sub-cellular localization, domain structure, membrane topology and enzymatic activi

189 s resemble Arabidopsis PIFs in their protein domain structure, molecular properties, and physiologica

190 ess has been made in determining central rod domain structure, no structural data have been reported

191 t each of the two individual RRMs retain the domain structure observed in complex with RNA but are no

192 lutionary intermediates that underlie the bi-domain structure observed in the expansive plant TPS gen

193 te to epochal evolution, we determined the P domain structure of a 2004 variant with ABH and secretor

194 O3 leads to dramatic changes of the magnetic domain structure of a neighboring magnetic layer (La1/2S

195 A computational model of a possible single-domain structure of Cd(8)-betaalpha-rhMT is described.

196 egulation in the context of the higher-order domain structure of chromatin as determined from recent

197 se discrepancies are partly explained by the domain structure of DHODH and suggest both assays are us

198 Although PxaTPS8 adopts the typical three-domain structure of diTPSs, sequence phylogeny places th

199 The modular domain structure of extracellular matrix (ECM) proteins

200 r, our findings highlight the flexible multi-domain structure of KCC2 with variable anchoring points

201 tive kinase inhibitors to characterizing the domain structure of multidomain proteins.

202 e, we solved by room temperature SFX the GAF domain structure of Pb to 1.55- angstrom resolution, whi

203 The domain structure of PDI is a-b-b'-x-a', wherein the thio

204 (SCAM) to investigate the membrane-spanning domain structure of PfENT1 to identify potential inhibit

205 The light chain binding domain structure of phosphorylated smHMM differs markedl

206 Although the domain structure of PTEN and the functional impact of a

207 The multi-domain structure of relaxors that is revealed by our mol

208 The domain structure of RPTPs comprises an extracellular reg

209 ow modulus can also be explained by the nano-domain structure of strain glass.

210 nd validated in cytokine receptors by the TM domain structure of the cytokine receptor common subunit

211 have a role in establishing the topological domain structure of the genome.

212 n microscopy, we show that the ferromagnetic domain structure of the manganite electrodes is imprinte

213 ar hysteresis loop resulting from a peculiar domain structure of the microwire.

214 domains of R-proteins, and reconstructed the domain structure of the protein containing the common an

215 R spectroscopy, we show that the overall BAR domain structure of the rat endophilin A1 dimer determin

216 tranded deoxyoligonucleotide established the domain structure of the STATs and the structural basis f

217 FF4-6) of TCERG1, revealing a rigid integral domain structure of the tandem FF repeat that interacts

218 le explains such differences in terms of the domain structure of these proteins.

219 We show here that the two domain structure of Tim44 plays a central role in this p

220 Analysis of the putative protein domain structure of UvrD2 shows a distinctive domain arc

221 The domain structure of variants GluR6D and GluR6E revealed

222 troscopy is further used to study the unique domain structures of 2D alpha-Mo(2) C crystals grown by

223 Here, we model the variable domain structures of a large set of post-phase-I clinica

224 The similar domain structures of alphavirus capsid proteins suggest

225 The two currently available receiver domain structures of atypical response regulators are ve

226 d compared it to the previously determined P domain structures of GI.1 and GI.2 strains.

227 d in complex with Cul3, along with the Kelch domain structures of KLHL2 (Mayven), KLHL7, KLHL12, and

228 olar pockets are also seen in the tandem LIM domain structures of LMO4 and Lhx3 bound to unrelated li

229 ating-current electric field to engineer the domain structures of originally opaque rhombohedral Pb(M

230 The domain structures of Spc97 and Spc98 suggest functions f

231 Here, the transmembrane domain structures of the helical membrane proteins are e

232 trates that there is no change in the lipoyl domain structure on complexation with E3.

233 , Anderson et al. (2019) show that chromatin domain structure on the X chromosome in C. elegans is di

234 ssed to drive PGNPs into spatially organized domain structures on submicrometer scale within topograp

235 on is through a process(es) in which protein domain structure plays a contributing factor.

236 long this process, we analyze the defect and domain structure quantitatively via video microscopy and

237 1/3 exhibit complicated antiphase and chiral domain structures related to ordering of intercalated Fe

238 gnetic skyrmions are topologically protected domain structures related to the Dzyaloshinskii-Moriya i

239 ll facilitate the further exploration of the domain-structure-related properties and potential applic

240 nce of JH III and found to have a double OBP domain structure reminiscent of salivary "long" D7 prote

241 TMC1 is thought to have a six-transmembrane domain structure reminiscent of some other ion-channel s

242 target capture complex together with our MLV domain structures, residues within the CCD alpha2 helica

243 found to exhibit an intriguing ferroelectric domain structure resulting from orthorhombic twins and (

244 Solving the RNA-binding domain structures revealed the canonical NS1 symmetrical

245 genetically conserved residues onto the WD40 domain structure reveals surface patches that may be imp

246 A comprehensive evaluation of PX domain structures reveals two distinct binding sites tha

247 Our analyses of C. elegans chromatin domain structure show that genes are organized by type i

248 The two apo-FGFR4 kinase domain structures show an activation segment similar in

249 Structural alignments of TOG3 with other TOG domain structures show that the architecture of TOG3 is

250 Analysis of an OMP with a domain structure similar to that of LptD, FhuA, suggests

251 Although OGTs with domain structures similar to those of eukaryotic OGTs ar

252 The surface magnetic domain structure (SMDS) parameters of 45 mum diameter Co

253 e electrical control of magnetic anisotropy, domain structure, spin polarization or critical temperat

254 ossati et al. (2016) report that through its domain structure, SRGAP2A, a Rho-GTPase-activating prote

255 mental and theoretical insights into various domain structures (such as polar spirals, polar wave, po

256 These observations, coupled with its domain structure, suggest that LrrB is an SH2 adaptor pr

257 -item questionnaire was found to have a four-domain structure ('symptoms', 'emotions', 'social life/f

258 ss of nanoparticles with an ordered, striped domain structure that can be readily manipulated by alte

259 The jaw joint is an intermediate-domain structure that expresses nkx3.2 and a more genera

260 n, all NB-ARC and NACHT domains) possessed a domain structure that included a STAND NTPase paired wit

261 but single-copy genes with a characteristic domain structure that may contain introns in evolutionar

262 Moreover, we report a unique C-terminal domain structure that participates in stabilizing the ov

263 ium (Kir) channel family share a cytoplasmic domain structure that serves as an unusual AP-1 clathrin

264 ar magnetic resonance revealed a classic LIM-domain structure that was highly related to LIM1 of PINC

265 y, we generalize the soft strain to generate domain structures that allow further tuning of the mater

266 teins revealed that they have unique modular domain structures that are divergent in sequence and siz

267 gives rise to instabilities of the magnetic domain structures that are reminiscent of Rayleigh-Plate

268 gments can provide accurate reporters on the domain structures that can be mapped directly to the int

269 e-cell DNA domain analysis in vivo, identify domain structures that change with cell identity, and sh

270 ver a dynamics of modular motif embedding in domain structures that is ongoing, which transfers 'pref

271 rved among the three determined CENP-C cupin domain structures, the cupin domains from organisms with

272 y of bottlebrush block copolymers into large domain structures, the self-assembly of bottlebrush bloc

273 Given the domain structures, this suggests that the molecules occu

274 r anisotropy and follow the evolution of the domain structure through part of its magnetization hyste

275 ation site of MASP-3, a protein with similar domain structure to C1s that is not normally cleaved by

276 that shows active-site homology and similar domain structure to eukaryotic OGTs.

277 ions of controlled nanoscale manipulation of domain structures to drive emergent properties, such app

278 o power conversion, depends crucially on its domain structure, traditionally crafted during materials

279 The mutant fusion domain structure was solved by NMR spectroscopy in a lip

280 spacing so strongly affects the larger-scale domain structure, we next examine the genome-wide linker

281 tinct differences in the TIM-1 and TIM-4 IgV domain structures, we sought to characterize TIM-4 IgV d

282 The domain structures were then docked in silico to provide

283 lume fraction of two geometrically different domain structures which are generated by two distinct sw

284 n is a crystallographic dimer with an I-type domain structure, which maintained in solution.

285 novel open state and has a unique C-terminal domain structure, which plays a crucial role in nsp10 he

286 tapa2072 that encode proteins with identical domain structure: while DeltarbdA showed elevated c-di-G

287 e archaeal Nop56/58 NTD exhibits a conserved domain structure whose exceptionally stable interaction

288 s, one of which we show to have a unique two domain structure with a novel regulatory"plug".

289 utations spread throughout the conserved RGS domain structure with a slight enrichment at positions t

290 The protease also has an atypically short domain structure with an odd number of Cys residues in t

291 CLEL precursors share a similar domain structure with CLE precursors (i.e., they contain

292 or that shares an otherwise highly conserved domain structure with members of the protein family, con

293 Although DLC2 shares a similar domain structure with that of DLC1, the function of DLC2

294 significant amino acid sequence homology and domain structure with the MukB protein of Escherichia co

295 ese eight structural variants form a Z4 x Z2 domain structure with Z3 vortices and five distinct type

296 xhibiting complex, nanotwinned ferroelectric domain structures with high densities of 90 degrees doma

297 yme was confirmed by comparing the motif and domain structure within and across the plant kingdom.

298 A unique 6-cysteine-rich domain structure within Pfs230 have thwarted its recombi

299 terpene synthases (TPSs) generally has a bi-domain structure, yet phylogenetic analyses consistently

300 nsmembrane domain and existing extracellular domain structures, yielding a complete conformational mo