ライフサイエンスコーパス: dopaminergic neuron

1 e aggregation and misfolding of alpha-syn in dopaminergic neurons.

2 e soma in rat substantia nigra pars compacta dopaminergic neurons.

3 pecifically target CRISPR-Cas9 components to dopaminergic neurons.

4 prevents cellular senescence in post-mitotic dopaminergic neurons.

5 neurons, as shown for both rodent and human dopaminergic neurons.

6 which is validated in Stmn2-knockdown mouse dopaminergic neurons.

7 or control, and makes synaptic contacts with dopaminergic neurons.

8 ET in mice during chemogenetic activation of dopaminergic neurons.

9 pression of the pro-senescence factor p21 in dopaminergic neurons.

10 mptoms due to the selective loss of midbrain dopaminergic neurons.

11 the development and maintenance of midbrain dopaminergic neurons.

12 son's disease, suggesting that DJ-1 protects dopaminergic neurons.

13 of PPN axons reliably evoked spiking in SNc dopaminergic neurons.

14 s, and induced pluripotent stem cell-derived dopaminergic neurons.

15 ir differentiation yields high percentage of dopaminergic neurons.

16 TA), subsequently increasing SP release onto dopaminergic neurons.

17 ns in TRP-4 reduce the mechanosensitivity of dopaminergic neurons.

18 maintenance of mitochondrial homeostasis in dopaminergic neurons.

19 he membrane potential of mitochondria in SNc dopaminergic neurons.

20 coupling it results in a greater loss of SNc dopaminergic neurons.

21 ted into reduced microglial toxicity towards dopaminergic neurons.

22 in which the mitochondrial DNA is damaged in dopaminergic neurons.

23 network and distinct subsets of reinforcing dopaminergic neurons.

24 tDNA) undergoes double-strand breaks only in dopaminergic neurons.

25 n-G (Ank-G) was used to visualize the AIS of dopaminergic neurons.

26 mice led to a clear age-related loss of SNc dopaminergic neurons.

27 ene function in specific subsets of midbrain dopaminergic neurons.

28 l1R), which modulate the activity of the VTA dopaminergic neurons.

29 mous activation of the UPR(MT) in C. elegans dopaminergic neurons.

30 e to mitochondrial mass (porin and GRP75) in dopaminergic neurons.

31 and differentiated them into macrophages and dopaminergic neurons.

32 endritic and striatal axonal compartments of dopaminergic neurons.

33 cell conversion can produce a high yield of dopaminergic neurons.

34 of the effect of parkin deficiency in human dopaminergic neurons.

35 sses minimizing prediction errors encoded by dopaminergic neurons.

36 cells, liver organoids, cardiomyocytes, and dopaminergic neurons.

37 sts or induced pluripotent stem cell-derived dopaminergic neurons.

38 ative stress, inflammation, and apoptosis in dopaminergic neurons.

39 ion in putative ventral tegmental area (VTA) dopaminergic neurons.

40 and relies on triggering specific rewarding dopaminergic neurons.

41 r cells and subsequently differentiated into dopaminergic neurons.

42 ential mechanism for manganese regulation of dopaminergic neurons.

43 expression increased and was co-located with dopaminergic neurons.

44 n of synaptic transmission in mesolimbic VTA dopaminergic neurons.

45 cally disordered protein highly expressed in dopaminergic neurons.

46 of dopamine released from stem cell-derived dopaminergic-neurons.

47 the robust degeneration of substantia nigra dopaminergic neurons, a pathological hallmark of PD.

48 duces energy intake by negatively modulating dopaminergic neuron activity and, in turn, hedonic aspec

49 is effect is triggered by a specific pair of dopaminergic neurons afferent to the mushroom bodies, vi

50 Here, we investigated whether REST protects dopaminergic neurons against Mn-induced toxicity and enh

51 dopamine neurotrophic factor (CDNF) protects dopaminergic neurons against toxic damage in the rodent

52 a broadly held expectation that degenerating dopaminergic neurons alone hold the key to understanding

53 on lipoprotein vesicles, and their uptake by dopaminergic neurons along with an increase of ApoE in e

54 ized by motor dysfunction, death of midbrain dopaminergic neurons and accumulation of alpha-synuclein

55 ine metabolism, triggers oxidative stress in dopaminergic neurons and alpha-Syn aggregation.

56 on handling might be involved, we focused on dopaminergic neurons and asked how inactivation of trans

57 Finally, we find that JH acts through dopaminergic neurons and conclude that an ETH-JH-dopamin

58 lar and anatomical heterogeneity of midbrain dopaminergic neurons and contribute to a better understa

59 nd sleep-independent memory rely on distinct dopaminergic neurons and corresponding mushroom body out

60 evoked abnormal plasticity in nigrostriatal dopaminergic neurons and DMS D1-neurons, contributing to

61 These MBONs, together with dopaminergic neurons and Dop1R2 signaling, control behav

62 t overexpression of KCNQ channels in the VTA dopaminergic neurons and either local infusion or system

63 striatal medium spiny neurons, adult nigral dopaminergic neurons and frontal cortical neurons.

64 3 results in impaired oxytocin signalling in dopaminergic neurons and in altered behavioural response

65 mine neurons both in human stem cell-derived dopaminergic neurons and in mice.

66 Thus, the concept of the presence of dormant dopaminergic neurons and its possibility as the disease-

67 g a fluorescent probe (BODIPY) revealed that dopaminergic neurons and midbrain microglia significantl

68 Moreover, loss of dopaminergic neurons and motor and non-motor symptoms we

69 cGAS/STING pathway, causing degeneration of dopaminergic neurons and motor impairment.

70 erscore the complex organization of midbrain dopaminergic neurons and provide an entry point for futu

71 DAT delivery to the presynaptic terminals of dopaminergic neurons and restored sleep to normal length

72 We identify progenitor cells for dopaminergic neurons and show that activating the immune

73 were significantly enriched in adult nigral dopaminergic neurons and striatal medium spiny neurons.

74 lpha-synuclein pathology, persistent loss of dopaminergic neurons and striatal neurotransmitters, and

75 ncluding the mechanosensory TRP-4 channel in dopaminergic neurons and the D2-like dopamine receptor D

76 tegmental area (VTA), which is the origin of dopaminergic neurons and the dopamine reward pathway.

77 chemical and immunoblot staining of midbrain dopaminergic neurons and their forebrain projections for

78 e arousal-promoting VTA glutamatergic and/or dopaminergic neurons and through projections to the late

79 rs, such as hunger, scale signals encoded by dopaminergic neurons and thus they alter the motivation

80 essive degeneration of nigrostriatal pathway dopaminergic neurons and widespread axonal pathology.

81 synuclein aggregation, increased survival of dopaminergic neurons, and improved locomotor functions.

82 link between sleep, neuronal reactivation of dopaminergic neurons, and memory consolidation.

83 th, differentiation and network formation of dopaminergic neuron- and astrocyte-like cell populations

84 in, this study reveals that not all types of dopaminergic neurons are functionally regenerated after

85 Low dopamine levels and death of the dopaminergic neurons are hallmarks of Parkinson's diseas

86 Midbrain dopaminergic neurons are highly heterogeneous.

87 Meso-diencephalic dopaminergic neurons are known to modulate locomotor beh

88 neurotoxicity in nerve cells, especially in dopaminergic neurons are not yet fully understood.

89 The mechanism by which dopaminergic neurons are selectively affected in Parkins

90 igra with significant reduction (-29.30%) of dopaminergic neurons as compared with controls.

91 SN neutral lipid content and distribution in dopaminergic neurons, astrocytes, and microglia relative

92 ngs to test for GABA-A receptors on the main dopaminergic neuron axons and branching processes within

93 gic and monoaminergic neurons (which include dopaminergic neurons) but also with enteric neurons and

94 We propose that disinhibiting dormant dopaminergic neurons by blocking excessive astrocytic GA

95 Second, it represses the generation of dopaminergic neurons by dorsolateral progenitors through

96 tion.SIGNIFICANCE STATEMENT Substantia nigra dopaminergic neurons can be divided into two populations

97 Relish knockdown in the dopaminergic neurons confers PQ resistance and rescues m

98 of reticulospinal neurons, meso-diencephalic dopaminergic neurons control the very last instructions

99 We find that optogenetic activation of the dopaminergic neuron DAN-i1 can both establish memory dur

100 Parkinson's disease (PD) is associated with dopaminergic neuron (DaN)-specific gene expression, incl

101 BON synapses receive a direct synapse from a dopaminergic neuron (DAN).

102 Dopaminergic neurons (DANs) drive learning across the an

103 arkinson's disease, characterized by loss of dopaminergic neurons (DaNs) in the substantia nigra (SNc

104 in obvious motor functional deficit, loss of dopaminergic neurons (DANs) in the substantia nigra pars

105 cterized by the preferential degeneration of dopaminergic neurons (DaNs) of the substantia nigra pars

106 Different types of Drosophila dopaminergic neurons (DANs) reinforce memories of unique

107 ibits two types of mushroom-body-innervating dopaminergic neurons (DANs) to promote thirst-specific w

108 Here, we purified iPSC-derived human dopaminergic neurons (DaNs) using the intracellular mark

109 the SNCA locus and differentiated them into dopaminergic neurons (DAns).

110 s, and in the modulation of that transfer by dopaminergic neurons (DANs).

111 Dopaminergic neurons (DAs) of the rodent substantia nigr

112 activity is one of the major hypotheses for dopaminergic neuron death in Parkinson's disease.

113 the mitochondrial complex I, does not cause dopaminergic neuron death or motor impairment.

114 t life, in tandem with research studying how dopaminergic neuron degeneration begins, is essential fo

115 eficial effects of estrogen on nigrostriatal dopaminergic neuron degeneration in postmenopausal drug-

116 2 kinase inhibitor significantly reduced the dopaminergic neuron degeneration in this interaction mod

117 ers, can appear years earlier than the overt dopaminergic neuron degeneration that drives motor abnor

118 Stmn2 reduction in the mouse midbrain causes dopaminergic neuron degeneration, phosphorylated alpha-s

119 racteristics of the disease with very subtle dopaminergic neuron degeneration.

120 isfolded alpha-synuclein and causes midbrain dopaminergic neuron degeneration.

121 mHTTx1) modulates the expression of IL-34 in dopaminergic neurons derived from a human embryonic stem

122 the translational landscape in LRRK2-mutant dopaminergic neurons derived from human induced pluripot

123 Dopaminergic neurons derived from induced pluripotent st

124 ound to protect against neurodegeneration of dopaminergic neurons derived from iPSCs.

125 Here we studied dopaminergic neurons derived from patients with idiopath

126 ell proliferation, developmental timing, and dopaminergic neuron development.

127 e are attributed to degeneration of midbrain dopaminergic neurons (DNs).

128 rise to interregional assemblies that drive dopaminergic neurons during stimulus-outcome learning.

129 ity between mushroom body output neurons and dopaminergic neurons enables memory re-evaluation driven

130 The dopaminergic neurons encode differences between rewards

131 Activity changes in dopaminergic neurons encode the ongoing discrepancy betw

132 differentiation of neuronal precursors into dopaminergic neurons (Engrailed 1) and for the oligodend

133 with attenuated IP(3)Rs in these presynaptic dopaminergic neurons exhibit shortened flight bouts and

134 p after the learning experience and activate dopaminergic neurons for memory consolidation.

135 Here we report that NCEH-1 protects dopaminergic neurons from alpha-synuclein-dependent neur

136 on, in induced pluripotent stem cell-derived dopaminergic neurons from patients with parkin (PARK2) g

137 Dopaminergic neurons from patients with Type 2 and Type

138 l redox status and membrane potential of SNc dopaminergic neurons from Sirt3 knockouts.

139 motor features that arise due to the loss of dopaminergic neurons from the substantia nigra.

140 ressive neurodegenerative disorder involving dopaminergic neurons from the substantia nigra.

141 n of functionally important neurons, such as dopaminergic neurons, from endogenous progenitor cells i

142 ls, suggesting a role for ErbB4 signaling in dopaminergic neuron function.

143 ronal morphology and firing rate showed that dopaminergic neurons function as a coupled oscillator wh

144 n of GDNF in the CNS affects the function of dopaminergic neurons has remained unknown.

145 Our study reveals that dopaminergic neurons have access to command neurons that

146 reticular nuclei, which retrogradely labeled dopaminergic neurons in a caudal diencephalic nucleus (p

147 at CIB1 negatively regulates degeneration of dopaminergic neurons in a mouse model of Parkinson's dis

148 r, sensory, memory and learning) and loss of dopaminergic neurons in both males and females.

149 gene enhances MPTP-induced neurotoxicity in dopaminergic neurons in CIB1(-/-) mice.

150 hrough DAT in heterologous cells and primary dopaminergic neurons in culture.

151 O) acts as a neurotransmitter in a subset of dopaminergic neurons in Drosophila.

152 rain region known for the involvement of its dopaminergic neurons in encoding reward-related features

153 on along axons, and presynaptic densities at dopaminergic neurons in every fly brain region.

154 K1 and Parkin/PRKN cause the degeneration of dopaminergic neurons in familial forms of Parkinson's di

155 imal and human investigations indicates that dopaminergic neurons in lateral substantia nigra, which

156 tier and calbindin-negative ventral tier SNc dopaminergic neurons in mice comprise functionally disti

157 loss of substantia nigra pars compacta (SNc) dopaminergic neurons in Parkinson's disease (PD).

158 can lead to long term stable preservation of dopaminergic neurons in PD-related mouse models remains

159 tochondrial oxidative stress and loss of SNc dopaminergic neurons in PD.

160 , accompanied by progressive degeneration of dopaminergic neurons in SN, neuritic swelling, reduced s

161 nce of ApoE-positive neuromelanin-containing dopaminergic neurons in substantia nigra of PD patients.

162 neurons, did not cause a significant loss of dopaminergic neurons in substantia nigra pars compacta (

163 eased rotarod and wirehang activity, reduced dopaminergic neurons in substantia nigra pars compacta (

164 ffeine action, we have identified a role for dopaminergic neurons in the arousal-promoting effect of

165 Additionally, dopaminergic neurons in the goal-directed system play a

166 enerative disorder, characterized by loss of dopaminergic neurons in the midbrain.

167 The roles of dopaminergic neurons in the modulation, structuring and

168 stem to decipher the roles of two classes of dopaminergic neurons in the mouse nucleus accumbens in a

169 went unilateral transplantation of embryonic dopaminergic neurons in the putamen and subsequently exh

170 y projection neurons than onto the somata of dopaminergic neurons in the SNpc or dorsal striatal chol

171 this, RGMa induced selective degeneration of dopaminergic neurons in the substantia nigra (SN) and af

172 terized by the progressive loss of pigmented dopaminergic neurons in the substantia nigra and associa

173 disease (PD) show selective degeneration of dopaminergic neurons in the substantia nigra and choline

174 son's disease (PD) is defined by the loss of dopaminergic neurons in the substantia nigra and the for

175 Degeneration of dopaminergic neurons in the substantia nigra causes the

176 Progressive degeneration of dopaminergic neurons in the substantia nigra pars compac

177 PD is characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compac

178 Most dopaminergic neurons in the substantia nigra pars compac

179 parkin have been implicated in the death of dopaminergic neurons in the substantia nigra, which is t

180 motor symptoms due to the selective loss of dopaminergic neurons in the substantia nigra.

181 terized by slow, progressive degeneration of dopaminergic neurons in the substantia nigra.

182 's disease (PD) characterized by the loss of dopaminergic neurons in the substantia nigra.

183 ecific marker for a novel subset of midbrain dopaminergic neurons in the ventral midbrain that projec

184 (CB1Rs) on GABAergic neurons that disinhibit dopaminergic neurons in the ventral tegmental area (VTA)

185 u haploinsufficiency causes prenatal loss of dopaminergic neurons in the ventral tegmental area and r

186 Moreover, activation of dopaminergic neurons in the ventral tegmental area follo

187 Opiates increase the firing rates of dopaminergic neurons in the VTA by acting on mu-opioid r

188 and rescued by optogenetic inhibition of non-dopaminergic neurons in the VTA.

189 resolve the morphology of most, if not all, dopaminergic neurons in the whole adult brain (3.64 x 10

190 Thus, PPN-evoked burst spiking of SNc dopaminergic neurons in vivo may not only be extrinsical

191 fic dysregulation, exacerbates disruption of dopaminergic neurons in vivo, resulting in the neurodege

192 fects on the survival and function of nigral dopaminergic neurons in which the chronic expression of

193 thout an increase in the numbers of midbrain dopaminergic neurons, in conditional Zeb2 (Nestin-Cre ba

194 icient for survival and early maintenance of dopaminergic neurons, indicating that the D620N VPS35 pr

195 Axons of dopaminergic neurons innervate the striatum where they c

196 ization requires odor-evoked activity in the dopaminergic neuron innervating this compartment.

197 This pathway recruits negatively reinforcing dopaminergic neurons innervating the same compartment an

198 king in substantia nigra pars compacta (SNc) dopaminergic neurons is a key signaling event in the cir

199 ation of human pluripotent stem cell-derived dopaminergic neurons is a promising approach to treating

200 related decline in proportions of submucosal dopaminergic neurons is exacerbated in Cdnf (-/-) animal

201 But REST's role in dopaminergic neurons is unclear.

202 Dopaminergic neurons labeled by tracer injections in the

203 aracterization of a novel subset of midbrain dopaminergic neurons located in the ventral tegmental ar

204 cting all amino acids effectively suppresses dopaminergic neuron loss and locomotor deficits and is a

205 h E46K-like mutants have been shown to cause dopaminergic neuron loss and severe but L-DOPA-responsiv

206 ent synaptic disruption, occur in absence of dopaminergic neuron loss in PD.

207 n DSP-4 (50 mg/kg), then the motor activity, dopaminergic neuron loss, colon gene expression and gut

208 e have reduced reward sensitivity related to dopaminergic neuron loss, which is associated with impai

209 nt gut pro-inflammatory gene expression, and dopaminergic neuron loss.

210 ikely resulting from DNA hypomethylation, in dopaminergic neurons may contribute to the initial stage

211 ous expression of Nav 1.2 by the majority of dopaminergic neurons may explain their high threshold fo

212 These results suggest that CB2Rs in dopaminergic neurons may play important roles in the mod

213 2 (lm-alpha2) is a component of the midbrain dopaminergic neuron (mDA) progenitor niche in the ventra

214 tau in maintaining the survival of midbrain dopaminergic neurons (mDANs) during aging.

215 ssed alpha-syn A53T mutation in the midbrain dopaminergic neurons (mDANs) with different expression l

216 priate connections for cell therapy.Midbrain dopaminergic neurons (mDAs) in the VTA and SNpc project

217 Midbrain dopaminergic neurons (mesDA) are the nerve cells prefere

218 kin mutant phenotypes, in particular loss of dopaminergic neurons, mitochondrial network structure, r

219 ion of CDNF to ENCDC promotes development of dopaminergic neurons; moreover, survival of these neuron

220 e in which Ndufs4 was selectively deleted in dopaminergic neurons (Ndufs4 cKO).

221 riments demonstrate that Neurod6(+) midbrain dopaminergic neurons neurons project to two distinct sep

222 ons alone did not alter the number of nigral dopaminergic neurons nor striatal dopamine levels.

223 rease in the expression of COMT was found in dopaminergic neurons of isogenic PARK2 induced pluripote

224 Dopaminergic neurons of LRRK2 G2019S transgenic and LRRK

225 studies reporting mtDNA depletion in nigral dopaminergic neurons of PD patients.

226 as via the projections from reward-sensitive dopaminergic neurons of the midbrain ventral tegmental a

227 rable in Parkinson's disease (PD), including dopaminergic neurons of the substantia nigra (SN) and ch

228 X1 and NFE2L1 levels are severely reduced in dopaminergic neurons of the substantia nigra of Parkinso

229 us deep brain stimulation (STN DBS) protects dopaminergic neurons of the substantia nigra pars compac

230 synuclein in primary cultured neurons and in dopaminergic neurons of the substantia nigra pars compac

231 ice, overexpression of COMT, specifically in dopaminergic neurons of the substantia nigra, produced c

232 disease are attributed to selective loss of dopaminergic neurons of the substantia nigra.

233 extensive molecular and synaptic changes in dopaminergic neurons of the ventral tegmental area, incl

234 asmalemmal Cav2.3 protein was higher than in dopaminergic neurons of the ventral tegmental area, whic

235 e reward circuitry, altering the activity of dopaminergic neurons of the ventral tegmental area.

236 In dopaminergic neurons of VTA slices, orexin A presynaptic

237 d is associated with the progressive loss of dopaminergic neurons over the course of aging.

238 population of protocerebral anterior medial dopaminergic neurons (PAM DANs) that innervates the beta

239 its.SIGNIFICANCE STATEMENT Meso-diencephalic dopaminergic neurons play a key role in modulating locom

240 Hence, dopaminergic neuron populations in the adult zebrafish b

241 Here we ask whether the loss of various dopaminergic neuron populations is sufficient to trigger

242 Mesostriatal dopaminergic neurons possess extensively branched axonal

243 , RNAi-mediated depletion of CIB1 in primary dopaminergic neurons potentiated 1-methyl-4-phenyl pyrin

244 ator protein 18, ameliorates degeneration of dopaminergic neurons, preserves striatal dopamine metabo

245 e somatodendritic domain of adult male mouse dopaminergic neurons, previously recorded in vivo We obs

246 In mammals [1, 2] and fishes [3, 4], central dopaminergic neurons project to the inner ear and could

247 Midbrain dopaminergic neurons project via the nigrostriatal pathw

248 In this framework, dopaminergic neurons projecting to different parts of th

249 both inhibitory and excitatory inputs to VTA dopaminergic neurons projecting to the NAc medial shell

250 aptic tracing and calcium imaging identified dopaminergic neurons projecting to the protocerebral bri

251 that mitochondrial complex I dysfunction in dopaminergic neurons promotes non-motor symptoms of Park

252 ypical Lewy bodies, in 11-12% of the grafted dopaminergic neurons, reflecting the spread of pathology

253 rgic neurons.SIGNIFICANCE STATEMENT Midbrain dopaminergic neurons regulate diverse brain functions, i

254 Consistently, Dpp receptor signaling in dopaminergic neurons regulates TH expression and feeding

255 tanding how the firing of different types of dopaminergic neuron relates to movement and how this act

256 Some dopaminergic neurons release both dopamine and nitric ox

257 Here, we report in lampreys that dopaminergic neurons release dopamine in the four reticu

258 In vivo dopaminergic neuron reprogramming by EMF stimulation of

259 nd TRPN-like channels in the serotonergic or dopaminergic neurons, respectively, and the acute pharma

260 The loss of dopaminergic neurons results in decreased dopamine (DA)

261 Stereological counts of nigral dopaminergic neurons revealed a significantly greater ce

262 Reconstructions of sampled AIS of dopaminergic neurons revealed variable lengths (12-60 mu

263 We find that a spinally directed lesion of dopaminergic neurons reverses hyperalgesic priming in bo

264 ontribution of dysfunctional SVE to midbrain dopaminergic neurons' selective vulnerability and highli

265 nctions of the Neurod6(+) subset of midbrain dopaminergic neurons.SIGNIFICANCE STATEMENT Midbrain dop

266 ydroxylase (TH) from the TH-negative dormant dopaminergic neurons, some of which still express DOPA d

267 protects against MA-induced degeneration of dopaminergic neurons, suggesting that TAAR1 plays a role

268 y reveals a beneficial effect of Emapunil on dopaminergic neuron survival, dopamine metabolism, and m

269 ory neuroprotective PK2 signalling in nigral dopaminergic neurons that could have important therapeut

270 oom body, which drive negatively reinforcing dopaminergic neurons that innervate neighbouring zones.

271 icient replacement of functionally important dopaminergic neurons that later disappear.

272 is mediated by reactivation during sleep of dopaminergic neurons that were earlier involved in memor

273 nction, plasticity, and survival of midbrain dopaminergic neurons, the dysfunction of which contribut

274 Additionally, dopaminergic neurons themselves require D2R, suggesting

275 red branch-specific plastic changes in these dopaminergic neurons, thus enabling sustained protein co

276 e normal development and survival of enteric dopaminergic neurons; thus, expression of the dopaminerg

277 rtment and re-engages positively reinforcing dopaminergic neurons to reconsolidate the original rewar

278 nuclein accumulation and the degeneration of dopaminergic neurons, two major features of PD pathology

279 tem cells even yield two identical series of dopaminergic neuron types, but with unrelated sister neu

280 vidence that glutamatergic transmission onto dopaminergic neurons underlies incentive motivation, a w

281 in mouse, we targeted RGMa to adult midbrain dopaminergic neurons using adeno-associated viral vector

282 ex I activity in all cells or selectively in dopaminergic neurons via conditional deletion of the Ndu

283 The degeneration of dopaminergic neurons was accompanied by a strong microgl

284 lls, oligodendrocytes, microglial cells, and dopaminergic neurons was not significantly different.

285 umber of histamine neurons that surround the dopaminergic neurons was significantly reduced.

286 ABAergic inputs onto DMS-projecting midbrain dopaminergic neurons was suppressed.

287 ring of substantia nigra pars compacta (SNc) dopaminergic neurons, we identified and characterized th

288 In addition to their ascending projections, dopaminergic neurons were found to increase locomotor mo

289 at mutant primary cortical and mesencephalic dopaminergic neurons were more susceptible to rotenone-i

290 cases of synaptic innervation of the AIS of dopaminergic neurons were observed.

291 te of the effect that alpha-synuclein has on dopaminergic neurons, where its accumulation causes neur

292 acetylation, decreased MnSOD activity in SNc dopaminergic neurons, whereas mutagenesis of lysine 68 t

293 orrelated with elevated activity of midbrain dopaminergic neurons, whereas synchronous firing of ChIN

294 E cells regulate EB-RNs via identified PPM3 dopaminergic neurons, which project to the EB and are no

295 we show conversion of midbrain astrocytes to dopaminergic neurons, which provide axons to reconstruct

296 )R(DN) helped identify key flight-modulating dopaminergic neurons with axonal projections in the mush

297 D) is characterized by a progressive loss of dopaminergic neurons with limited treatment options.

298 th factor 20 (FGF20) supports maintenance of dopaminergic neurones within the nigrostriatal pathway.

299 s occurred selectively in calbindin-negative dopaminergic neurons within the SNc.

300 PRKN mutant patient fibroblasts with a high dopaminergic neuron yield.