ライフサイエンスコーパス: dormancy

1 ing maturation and help to establish primary dormancy.

2 uring mixotrophic growth and transition into dormancy.

3 eatment leads to apical growth cessation and dormancy.

4 styles such as swimming, colony formation or dormancy.

5 mechanisms of B. pseudomallei virulence and dormancy.

6 ession by promoting an asymptomatic state of dormancy.

7 synthesized in Pseudomonas aeruginosa during dormancy.

8 equence with DOG1, a major regulator of seed dormancy.

9 hout causing DNA breaks or allowing cellular dormancy.

10 reast cancer recurrence following metastatic dormancy.

11 grain size but have minimal effects on seed dormancy.

12 duces Pfkfb3 expression and elicits cellular dormancy.

13 ALN expression and further promotion of seed dormancy.

14 ing activity required for homeostasis during dormancy.

15 in regulation of both entry and release from dormancy.

16 ld potentially be overcome by improving seed dormancy.

17 ALLANTOINASE (ALN), a negative regulator of dormancy.

18 ation to maintain thermogenic fitness during dormancy.

19 INATION 1 (DOG1) are essential regulators of dormancy.

20 an important role of DNA methylation in seed dormancy.

21 the root system Spartina alterniflora during dormancy.

22 gence of offspring across multiple years via dormancy.

23 m the environment to promote the breaking of dormancy.

24 ecessary and sufficient to release HBCs from dormancy.

25 on traits, including flowering time and seed dormancy.

26 also proposed to be involved in controlling dormancy.

27 also had reduced ability to resuscitate from dormancy.

28 can be prevented by a property known as seed dormancy.

29 y altering the extent of female reproductive dormancy.

30 e function in modulating seed maturation and dormancy.

31 g treatment by entering cell cycle arrest or dormancy.

32 ARF16 that are involved in establishment of dormancy.

33 s the only option for the treatment of tumor dormancy.

34 a negative correlation between dispersal and dormancy.

35 he need for bet hedging through among-season dormancy.

36 through cell wall remodelling to confer coat dormancy.

37 bility to undergo amitotic budding to escape dormancy.

38 rosis, and facilitate tumor metastasis after dormancy.

39 ce on the capacity of this organism to enter dormancy.

40 owth arrest commonly referred to as cellular dormancy.

41 ATION1 (DOG1) is a primary regulator of seed dormancy.

42 ecause of our limited understanding of tumor dormancy.

43 last 300 ky, as well as the longest previous dormancy (50 ky) in that time span.

44 the majority of seeds exhibit 'physiological dormancy' - a quiescence program initiated by either the

45 Most alpine plants show physiological seed dormancy, a strong need for cold stratification, warm-cu

46 The emergence of persisters from dormancy after antibiotic withdrawal leads to recurrent

47 vidence that cancer cells under duress enter dormancy after cannibalizing MSCs.

48 lose HSCs and show a disrupted re-entry into dormancy after exposure to inflammatory stress stimuli.

49 but not Notch2, is required to maintain HBC dormancy after selective neuronal degeneration.

50 pletion of germination and its regulation by dormancy also depend on the degradation of specific subs

51 TION1 (DOG1) gene is a key regulator of seed dormancy and a major quantitative trait locus in Arabido

52 ymal stem cells (MSCs), where it established dormancy and became highly nonresponsive to isoniazid, a

53 ate the molecular mechanisms for SD inducing dormancy and cessation in apical shoots.

54 control photoperiod to prevent the onset of dormancy and chilling exposure.

55 dosperm surrounding the radicle confers coat dormancy and controls germination responses through modu

56 Accumulation of DOG1 in seeds leads to deep dormancy and delayed germination in Arabidopsis.

57 analogs of the maturation programs, such as dormancy and desiccation tolerance, are also found in no

58 rheostat that fine-tunes the balance between dormancy and disease progression in PC dyscrasias.

59 ressors HSI2/VAL1 and HSL1/VAL2 silence seed dormancy and enable the subsequent germination and seedl

60 helial-to-mesenchymal transition, tumor cell dormancy and escape from immune surveillance, with emerg

61 Major alleles for seed dormancy and flowering time are well studied, and can in

62 segregating early and late alleles for seed dormancy and flowering time in a field experiment.

63 To examine how seed dormancy and flowering time shape annual plant life cycl

64 ongly upon interacting genetic variation for dormancy and flowering.

65 Thus, studies on comparing seed dormancy and germination among populations must consider

66 Therefore, genes affecting seed dormancy and germination are among those under strongest

67 Dormancy and germination characteristics of fresh and 6-

68 Seed dormancy and germination of S. bungeana differed with po

69 r-ripening and incubation conditions on seed dormancy and germination of Stipa bungeana, a perennial

70 s methylomes from the globular stage through dormancy and germination to understand the role of methy

71 ogy clustering revealed novel actors of seed dormancy and germination.

72 illing duration for their meristems to break dormancy and grow fruitfully.

73 nown about molecular events involved in cyst dormancy and hatching, two key steps of their developmen

74 y often followed prolonged periods of device dormancy and increased progressively in frequency over t

75 Strong dormancy and late-flowering genotypes were both necessar

76 Furthermore, the reduced dormancy and longevity phenotypes observed in the dog1 s

77 inated tumor cell extravasation and on tumor dormancy and metastatic outgrowth.

78 eased relative abundance of genes related to dormancy and osmoprotectants.

79 s of E. coli PI-7 expressed genes related to dormancy and persister cell formation during the late de

80 are capable of switching between cell cycle dormancy and proliferation.

81 mall-molecule inhibitors released cells from dormancy and promoted their proliferation.

82 The dynamics of hypnozoite dormancy and reactivation are well documented but the mo

83 K's third Marshall Symposium explored tumour dormancy and reawakening in all their forms.

84 Current pictures of the mechanisms of tumour dormancy and reawakening remain incomplete.

85 gesting that IKKbeta may contribute to tumor dormancy and recurrence of ER(+) disease.

86 nts to the potential importance of microbial dormancy and resting stages in the formation of a "buffe

87 QTL were identified for depth of seed dormancy and seedling emergence timing (SET).

88 Inhibition of lipid synthesis prevented dormancy and sensitized the organisms to isoniazid.

89 etagenome is enriched in genes involved with dormancy and sporulation.

90 article reviews growing evidence about tumor dormancy and suggests that (i) cellular malignancy is a

91 tations in one MIR156 subfamily enhance seed dormancy and suppress PHS with negligible effects on sho

92 We show that bZIP67 overexpression enhances dormancy and that bZIP67 protein (but not transcript) ab

93 inosa to resuscitate from starvation-induced dormancy and that HPF is the major factor associated wit

94 We show that ice1 or zou increases seed dormancy and the double mutant has an additive phenotype

95 vironment at secondary sites regulates tumor dormancy and the response of breast cancer cells to horm

96 vidence related to naturally occurring tumor dormancy and treatment-induced tumor dormancy at the sit

97 delling approach that considers among-season dormancy and within-season germination phenology of annu

98 tumor suppression, generally referred to as dormancy, and progression and metastasis.

99 rpin the long-standing mystery of metastasis dormancy, and represent a therapeutic target for elimina

100 case of memory in the form of increased seed dormancy, and that persisted one generation removed from

101 elopmental programs, such as flowering time, dormancy, and the circadian clock.

102 val of DTCs and microscopic metastases under dormancy, and the eventual outgrowth of overt metastases

103 st a critical role of RGN in prostate cancer dormancy, and the utility of RGN signaling and exosomal

104 ses temperature and photoperiod cues to time dormancy, and to switch between sexual and asexual repro

105 oteins, which regulate reserve accumulation, dormancy, and/or desiccation tolerance in seeds in a gen

106 formation on cellular processes that lead to dormancy; and (b) provide models that could account for

107 Overall, metabolism during dormancy appeared to involve discrete but interrelated e

108 luence resistance to therapy and duration of dormancy are largely unknown.

109 population enters into metabolic quiescence (dormancy) as persister forms.

110 suggest that personalized vaccines targeting dormancy-associated neoantigens, which can be given to p

111 rmation on seasonal changes occurring during dormancy at both the transcriptome and metabolite levels

112 alignant PCs, or at least induces functional dormancy at early stages, malignant PCs eventually evade

113 g tumor dormancy and treatment-induced tumor dormancy at the site of primary tumor and in distant org

114 Antibiotics can cause dormancy (bacteriostasis) or induce death (cidality) of

115 Six months of dry storage broke seed dormancy, broadened the temperature range for germinatio

116 Aged spores exhibited higher dormancy but could efficiently geminate in the presence

117 a key role for DOG1 in determining depth of dormancy, but did not support a direct role for DOG1 in

118 ion fraction and 2) induction vs. release of dormancy by cold.

119 chanistically, mir156 mutations enhance seed dormancy by suppressing the gibberellin (GA) pathway thr

120 At its simplest, dormancy can be imposed by the formation of a simple phy

121 Bacterial dormancy can take many forms, including formation of Bac

122 ther understand the mechanisms by which this dormancy control takes place in Arabidopsis (Arabidopsis

123 ocesses by ABA may have an essential role in dormancy control.

124 The bet-hedging patterns in the dispersal-dormancy correlation and the associated reproductive tra

125 understanding of local and metastatic tumor dormancy could lead to novel cancer therapeutics for the

126 After breaking of spore dormancy, Ctr6 localizes to the vacuole membranes that a

127 nome-wide expression patterns over an annual dormancy cycle in both ecotypes, identifying nine major

128 The principle QTL determining SET (SET1: dormancy cycling) is physically close on chromosome 5, b

129 a large variability between the green-up and dormancy dates estimated using the six different methods

130 further suberin-deficient mutants have seed dormancy defects.

131 gates-is an important indicator of bacterial dormancy depth, whose formation is promoted by decreased

132 ch individual survival cell shows different "dormancy depth," which in return regulates the lag time

133 tabolized to meet energy requirements during dormancy (diapause), which occurs during the last copepo

134 cs, dispersal aerodynamics, pericarp-imposed dormancy, diaspore abscisic acid (ABA) concentration, an

135 g the alleles from weedy rice lengthened the dormancy duration, and seeds survived in the soil remain

136 ICE1 and ZOU determine the depth of primary dormancy during maturation independently of their effect

137 n plays critical roles in regulation of seed dormancy during seed germination and early seedling grow

138 t but essential roles in the release of seed dormancy epistatic to DOG1.

139 unosuppressive injury response that promotes dormancy escape and tumor recurrence.

140 d prevented surgery- or chemotherapy-induced dormancy escape.

141 ed in floral induction, bulb maturation, and dormancy establishment.

142 tion event that could occur during malignant dormancy even before primary cancer is clinically detect

143 show an increased incidence of reproductive dormancy even in long photoperiod.

144 tive state by two previously uncharacterized dormancy factors that specifically target the functional

145 lants are viable yet show phenotypes in seed dormancy, flowering time, lateral root, and stomata form

146 otion that hops require vernalization and/or dormancy for the meristem to change from a vegetative to

147 onifers, leading to cessation of growth, bud dormancy, freezing tolerance and changes in energy metab

148 ated mechanism limiting the duration of seed dormancy functions across the Brassicaceae.

149 A seasonal period of dormancy further improves tolerance of buds to environme

150 rmatically predicted bacterial growth rates, dormancy genes and antibiotic synthesis genes, as well a

151 expression levels of DosR regulon-regulated dormancy genes were significantly reduced in the dkppx m

152 Seed dormancy governs the timing of germination, one of the m

153 Dormancy has been hypothesized to be an adaptive physiol

154 The concept of dormancy has been validated in C. neoformans from both e

155 ating resistance to therapy and an exit from dormancy have never been investigated.

156 hey can remain in a state of drought-imposed dormancy (hibernation) for many years.

157 lanations for how senescent cells persist in dormancy, how they manage the metabolically expensive pr

158 that seed coat suberin is essential for seed dormancy imposition by low temperature and that the excl

159 e suberin and tannin layers is important for dormancy imposition.

160 ages of spontaneous outbreak from metastatic dormancy in a mouse model and exhibits SOX9-dependent re

161 y a role in determining the depth of primary dormancy in Arabidopsis.

162 he DOG1 protein is a major regulator of seed dormancy in Arabidopsis.

163 oy distinct signaling pathways to induce DTC dormancy in bone.

164 lymphoma 6 (BCL6) as a critical regulator of dormancy in brown adipocytes but not for their commitmen

165 DKK3, vasorin and neogenin failed to induce dormancy in cells expressing dominant-negative p38alphaM

166 her levels in the cold, promote reproductive dormancy in female D. melanogaster Furthermore, we provi

167 ontrol of germination by coleorhiza-enforced dormancy in grasses is an example of the convergent evol

168 ns, which is manifested in the form of tumor dormancy in healthy individuals as well as in cancer sur

169 ure and light are well known to control seed dormancy in many plant species.

170 have established that M. tuberculosis gains dormancy in MSCs, which serve as a long-term natural res

171 screen to isolate mutants that fail to enter dormancy in response to variation in temperature during

172 nt grain yield regulator, also controls seed dormancy in rice.

173 tion of jasmonic acid-isoleucine and loss of dormancy in seeds of stressed plants.

174 ts exhibit reduced incidence of reproductive dormancy in simulated winter conditions, while flies ove

175 generates robust cycling between growth and dormancy in the interior of the colony, as predicted by

176 by repressing genes related to axillary bud dormancy in the SAM and negative regulators of cytokinin

177 ssion of RGN in prostate tumor cells induced dormancy in vivo, while following suppression of RGN tri

178 e molecular mechanisms underlying growth and dormancy in woody perennials are largely unknown.

179 Notch signaling maintains p63 levels and HBC dormancy, in contrast to its suppression of p63 expressi

180 N promoted multiple known hallmarks of tumor dormancy including activation of p38 MAPK, decrease in E

181 Strong dormancy increased within-season fecundity in an early-f

182 Thus, bone secretes multiple dormancy-inducing factors that employ distinct signaling

183 statectomy, suggesting that bone may provide dormancy-inducing factors.

184 ctuca sativa), we investigated levels of the dormancy-inducing hormone abscisic acid (ABA), three aux

185 ther dormant or non-dormant, but seeds whose dormancy-inducing pathways are activated to higher level

186 ding innate immunity; adaptive immunity; and dormancy induction, or programmed cell death.

187 e systems; and coupling between immunity and dormancy induction/programmed cell death.

188 Although dormancy is a regulated response in brown adipocytes to

189 Seed dormancy is a widespread and key adaptive trait that is

190 Cell dormancy is a widespread mechanism used by bacteria to e

191 Seed dormancy is an adaptive trait defining where and when pl

192 Seed dormancy is an adaptive trait preventing premature germi

193 Vegetative bud dormancy is an important adaptive process allowing survi

194 Summer dormancy is an important stress avoidance mechanism of c

195 This increased dormancy is associated with increased ABA levels, and ca

196 Mechanical dormancy is conferred by preventing full phase-II water

197 Seed dormancy is expected to provide ecological advantages by

198 eveloping seeds at the maturation stage when dormancy is induced, we used a nced2569 quadruple mutant

199 The function of ABA in dormancy is rather well understood, but the role of DOG1

200 This pericarp-imposed mechanical dormancy is released by the activity of common fungi, wh

201 (iv) the current duration of dormancy is similar to the timespan separating the major

202 When the favorable season is fleeting, seed dormancy is the only adaptive strategy.

203 The timing of dormancy is therefore a key seasonal adaptation, and it

204 However, the molecular mechanism of dormancy is yet poorly understood.

205 Dormancy levels are further enhanced by cold during seed

206 rt (Piskurewicz et al., 2016) we showed that dormancy levels are maternally inherited through the pre

207 ts, but there is a striking increase in seed dormancy levels.

208 spect of plant development from seed and bud dormancy, liberation of meristematic cells from the quie

209 hat the coleorhiza becomes reinforced during dormancy maintenance and weakened during germination.

210 arasites, but pathways involved in microbial dormancy, maintenance of genome integrity and ATP homeos

211 restimated among marine microscopic species, dormancy may be a highly significant factor for explaini

212 Reduction of seed dormancy mechanisms, allowing for rapid germination afte

213 a jasmonic acid-dependent reduction in seed dormancy, mediated by alteration of gibberellin and absc

214 implicates CSCs as key contributors to tumor dormancy, metastasis, and relapse in PC.

215 However, the advantage conferred by dormancy might ultimately depend on other seed attribute

216 rgy-conserving hypometabolic states, such as dormancy, might have evolved as a mechanism of tissue to

217 Migrating infected cells reactivate from dormancy more than non-migrating cells and exhibit diffe

218 Thus, measurements of dormancy must always be accompanied by analysis of envir

219 eruption is of the same order of the longest dormancies occurred in the past.

220 an important dynamic role in the control of dormancy of her progeny seed in response to environmenta

221 en-induced apoptosis may trigger escape from dormancy of microtumors by interfering with inflammation

222 ied a gene, Regucalcin (RGN), which promotes dormancy of prostate cancer.

223 e stochastic mutations may accumulate during dormancy of stem-like cells, but technical limitations i

224 s an oncogenic signal promoting an exit from dormancy of therapy-induced cancer stem-like cells and l

225 Seeds featuring this so-called 'physical dormancy' often require either scarification or passage

226 fer enhanced dispersal ability and degree of dormancy on the IND fruit morph to support telechory, wh

227 This can lead to dormancy or cell death; to avoid this, cells need a way

228 lized enzyme) that cleaves cOA and mitigates dormancy or death induction.

229 smit the signal to an effector inducing cell dormancy or death.

230 s, a prolonged activation can result in cell dormancy or death.

231 r proteins, leading to viral clearance, cell dormancy or death.

232 SPR-Cas immune responses result in bacterial dormancy or slowed growth, which suggests the outcomes f

233 the convergence point of the DOG1-regulated dormancy pathway and signalling by the plant hormone abs

234 We propose that the ABA and DOG1 dormancy pathways converge at clade A of type 2C protein

235 These dormancy phases can also be induced in growth chambers b

236 hesis or DELAY OF GERMINATION 1 reverses the dormancy phenotype without affecting the aberrant seed m

237 ccurred through selection of pre-adapted low dormancy phenotypes from the wild.

238 nd varicose (vcs) mutants displayed distinct dormancy phenotypes.

239 ormed mycobacterial whole-genome sequencing, dormancy phenotyping and drug-susceptibility analyses on

240 Tumour dormancy presents challenges for clinical control and op

241 iched in traits which emphasize survival and dormancy, rather than growth and activity; and the crypt

242 NA that regulates expression of the key seed dormancy regulator, DELAY OF GERMINATION1, is a typical

243 memory CD4 T-cell responses specific to Mtb dormancy related (DosR) latency, but not classical immun

244 fection, in particular early secreted versus dormancy related latency antigens expressed later, that

245 Among all the QTL, five summer dormancy related putative QTL were identified in R43-64

246 QTL associated with summer-dormancy related traits in tall fescue has significant b

247 onal germination depends on patterns of seed dormancy release or induction by cold and interacts with

248 by treatment with ethylene and with various dormancy release stimuli.

249 h we identified within a gene set induced by dormancy release stimuli.

250 gene is down-regulated in flower buds after dormancy release, concomitantly with changes in the meth

251 ene signaling appears critical for grape bud dormancy release.

252 g that they participate in the regulation of dormancy release.

253 L1 in regulation of DOG1 expression and seed dormancy remain elusive.

254 ms regulating their maintenance or exit from dormancy remain uncertain.

255 t of multiple myeloma, may assume a state of dormancy, remaining quiescent for years before resuming

256 phenotypes, but whether it also affects seed dormancy remains unexplored.

257 ation of the phage into the host genome, and dormancy (resulting in vertical transmission)(1).

258 Seed dormancy (SD) and longevity (SL) may share developmental

259 We find that higher among-season dormancy selects for earlier germination within the grow

260 Conversely, dormancy should be evolutionarily stable in temperate li

261 ve, suggesting that BMP1 uses an alternative dormancy signaling pathway.

262 significance expressed higher levels of the dormancy signature genes than patients with multiple mye

263 se in overall survival, indicating that this dormancy signature may be a marker of disease progressio

264 However, gaps in our knowledge as to dormancy-specific antigens prevent a relapse preventing

265 tions must consider year of collection, seed dormancy states and germination test conditions when sel

266 mycobacterial genomic variants, lineage, nor dormancy status predicted cough aerosol culture positivi

267 stic leukemia that combine the phenotypes of dormancy, stemness, and chemo-resistance.

268 Strong seed dormancy suppressed mid-summer germination in both early

269 nism to explain ecotypic differences in seed dormancy that are controlled by the DOG1 locus.

270 Eradicating tumor dormancy that develops following epidermal growth factor

271 Regulation of embryonic diapause, dormancy that interrupts the tight connection between de

272 The impact of brumation, the winter dormancy that is observed in ectotherms, on memory remai

273 In other types of seeds with 'morphological dormancy' the embryo remains under-developed at maturity

274 Due in part to their apparent dormancy, the effect of PGCCs on cancer progression has

275 In dormancy, the hydrogel harvests water molecules from the

276 separate photoperiod from vernalization and dormancy through a series of experiments that artificial

277 asorin and neogenin, but not BMP1, increased dormancy through activating the p38MAPK signaling pathwa

278 l point of view with the characterization of dormancy through the description of viable but noncultur

279 functional categories underlie variation in dormancy timing and overlap with gene sets associated wi

280 Switching from dormancy to colonization is the rate-limiting step of bo

281 ake were up-regulated during transition from dormancy to hydration.

282 ge organs, sperm transition from a period of dormancy to rapid motility-a critical prerequisite for s

283 erived moisture and a transition from winter dormancy to spring activity.

284 s (with and without exposure to chilling and dormancy) to quantify the impact on flowering performanc

285 pulations in heterogeneous states, including dormancy, to eventually survive at low metabolic cost an

286 q) analysis to show that the transition from dormancy toward cell-cycle entry is a continuous develop

287 Vernalization and dormancy, two plant traits previously considered necessa

288 study, UABs induced into the three phases of dormancy under controlled conditions were used to compar

289 These UABs undergo seasonal phases of dormancy under natural conditions, namely para-, endo-,

290 conditions, and their levels peak at deepest dormancy under vineyard conditions.

291 Physiological dormancy uses germination-inhibiting hormones to prevent

292 Dormancy was also reduced by engineering seed-specific a

293 Seed dormancy was analysed by measurement of maximum germinat

294 Loss of dormancy was dependent on an intact jasmonate signalling

295 Altered dormancy was only observed in the first generation follo

296 Conversely, winter dormancy was transient at warmer locations, and GPP was

297 uranium-rich biotope, showed no evidence of dormancy when exposed to this metal.

298 iew of rhizome metabolism, especially during dormancy, which can be exploited in the future to improv

299 This timing is controlled by seed dormancy, which prevents germination under favourable co

300 ancer cells can induce a reversible state of dormancy, with decreased viral antigen synthesis and inc