ライフサイエンスコーパス: dorsal horn neuron

1 (i.e., calbindin-immunoreactive neurons and dorsal horn neurons).

2 afferent terminals vs inhibitory synapses on dorsal horn neurons).

3 e of central sensitization (hyperactivity of dorsal horn neurons).

4 ons preferentially target certain classes of dorsal horn neuron.

5 oked EPSCs and puff NMDAR currents in spinal dorsal horn neurons.

6 AMPAR Ca(2+) permeability at the synapses in dorsal horn neurons.

7 ergic action and transmission in superficial dorsal horn neurons.

8 the spinal cord and oxidative DNA damage in dorsal horn neurons.

9 rents and increased neuronal excitability in dorsal horn neurons.

10 internalization of micro-opioid receptors in dorsal horn neurons.

11 ownstream of mGlu5 activation in spinal cord dorsal horn neurons.

12 on of Kv4.2-containing potassium channels in dorsal horn neurons.

13 dly attenuated hyperresponsiveness of lumbar dorsal horn neurons.

14 drive from the primary afferent fibres onto dorsal horn neurons.

15 cated that NR1 is colocalized with mGluR5 in dorsal horn neurons.

16 in ERK phosphorylation (pERK) in superficial dorsal horn neurons.

17 CREB-mediated transcriptional regulation in dorsal horn neurons.

18 ectively together induce pERK in superficial dorsal horn neurons.

19 ent the activation of extrasynaptic MOR-1 in dorsal horn neurons.

20 d with enhanced neuronal responses in spinal dorsal horn neurons.

21 signal-regulated kinase (ERK) in superficial dorsal horn neurons.

22 ntiation of excitatory inputs to some of the dorsal horn neurons.

23 nce excitatory transmission onto spinal cord dorsal horn neurons.

24 ive fibers may terminate onto NK1-expressing dorsal horn neurons.

25 alpha8 protein was localized only in sensory dorsal horn neurons.

26 ry sensory neurons and intrinsic spinal cord dorsal horn neurons.

27 regulation of glutamate release onto spinal dorsal horn neurons.

28 ed with prodynorphin and NK-1 in superficial dorsal horn neurons.

29 the bilateral receptive fields for selective dorsal horn neurons.

30 tween kainate receptors expressed by DRG and dorsal horn neurons.

31 tion of group I mGluRs with activated ERK in dorsal horn neurons.

32 eceptor-mediated EPSCs in cultures of spinal dorsal horn neurons.

33 ls evoked by primary afferent stimulation in dorsal horn neurons.

34 no effect on excitatory transmission between dorsal horn neurons.

35 lasticity via modulation of ERK signaling in dorsal horn neurons.

36 mulation of the tibial nerve activated these dorsal horn neurons.

37 ons were now immunoreactive as well as a few dorsal horn neurons.

38 ited at the Q/R site both in motoneurons and dorsal horn neurons.

39 tly more vulnerable to AMPA and kainate than dorsal horn neurons.

40 nd to compare these properties with those of dorsal horn neurons.

41 SP-induced NK-1 receptor internalization in dorsal horn neurons.

42 effector genes, again in primary sensory and dorsal horn neurons.

43 it activity were examined for 68 superficial dorsal horn neurons.

44 messages are mediated by glutamate action on dorsal horn neurons.

45 larizing shift in GABA reversal potential of dorsal horn neurons.

46 Ca(2+) release-activated Ca(2+) channels in dorsal horn neurons.

47 e, we demonstrate that SOCs are expressed in dorsal horn neurons.

48 orsal root and puff NMDAR currents in spinal dorsal horn neurons.

49 ion of SOCs produced an excitatory action in dorsal horn neurons.

50 lutamatergic input from primary afferents to dorsal horn neurons.

51 stent hyperexcitability of these superficial dorsal horn neurons.

52 activity-dependent Fos expression in spinal dorsal horn neurons.

53 mbined with markers of primary afferents and dorsal horn neurons.

54 be coexpressed in postsynaptic densities in dorsal horn neurons.

55 ine-mediated currents (E(glycine)) in spinal dorsal horn neurons.

56 to the regulation of glutamatergic input to dorsal horn neurons.

57 s and the resulting synaptic transmission to dorsal horn neurons.

58 types inhibits synaptic glutamate release to dorsal horn neurons.

59 hins are present in different populations of dorsal horn neurons.

60 t icilin modulates the mechanosensitivity of dorsal horn neurones.

61 potentiation of glycinergic input to spinal dorsal horn neurones.

62 We conclude that MOR-expressing dorsal horn neurons (1) are not essential for determinin

63 (1) partial loss of lamina II MOR-expressing dorsal horn neurons, (2) no effect on MOR-expressing dor

64 d excitatory synaptic transmission in spinal dorsal horn neurons, a mechanism by which NMU stimulates

65 In spinal cord dorsal horn neurons, A-type currents are modulated by ex

66 w a loss of a subpopulation of glutamatergic dorsal horn neurons, abnormal sensory afferent innervati

67 after peripheral nerve injury, second-order dorsal horn neurons abnormally express Na(v)1.3, which (

68 rat: the visceromotor reflex (vmr) and L6-S1 dorsal horn neuron activity (ABRUPT and SUSTAINED neuron

69 ulation of rat ACC depressed the spinal cord dorsal horn neuron activity in response to noxious stimu

70 nal Fos expression, and colonic afferent and dorsal horn neuron activity were apparent by 1 week and

71 fect is through the modulation of the spinal dorsal horn neuron activity.

72 Fifty-two of 53 dorsal horn neurons affected by CPSA stimulation were ex

73 zation, increased sensitivity in spinal cord dorsal horn neurons after injuries, plays an essential r

74 of N-methyl-d-aspartate (NMDA) receptors in dorsal horn neurons after intradermal injection of capsa

75 and phosphorylation of CaMK II in rat spinal dorsal horn neurons after noxious stimulation by intrade

76 ein translation, was activated in rat spinal dorsal horn neurons after repeated intrathecal morphine

77 stribution in primary afferent terminals and dorsal horn neurons allows for multiple, circuit-specifi

78 at ATP induces ROS production in spinal cord dorsal horn neurons, an effect eliminated by ROS scaveng

79 chanical and thermal hypersensitivity of rat dorsal horn neurones and enhanced perceptual responses o

80 measured as augmented evoked activity of rat dorsal horn neurones and increased perceptual responses

81 hecal injection of GDNF activated rat lumbar dorsal horn neurones and inhibited intrathecal SP-induce

82 ury (SCI) can result in hyperexcitability of dorsal horn neurons and central neuropathic pain.

83 ously shown to be expressed in glutamatergic dorsal horn neurons and critical for dorsal horn develop

84 We investigated the role of spinal dorsal horn neurons and descending circuitry in plastici

85 ed an increase in c-Fos expression in spinal dorsal horn neurons and displayed increased evoked activ

86 , ERK-mediated modulation of excitability in dorsal horn neurons and ERK-dependent forms of pain hype

87 1R; encoded by Tacr1) is expressed in spinal dorsal horn neurons and has been suggested to mediate it

88 2 mediates the majority of A-type current in dorsal horn neurons and is a critical site for modulatio

89 lular signal-regulated kinase) activation in dorsal horn neurons and its contribution to central sens

90 reveal that a novel SOC signal is present in dorsal horn neurons and may play an important role in pa

91 lted in a decrease in hyperresponsiveness of dorsal horn neurons and partial restoration of behaviora

92 Recordings of synaptic currents in dorsal horn neurons and population synaptic potentials i

93 rotein (CREB) phosphorylation in superficial dorsal horn neurons and produced heat hyperalgesia after

94 consequence of superoxide build-up in spinal dorsal horn neurons and SOD-2 is a major determinant.

95 differentiation and migration of superficial dorsal horn neurons and subsequent ingrowth of cutaneous

96 at the B2 kinin receptor is expressed in rat dorsal horn neurons and that bradykinin, a B2-specific a

97 orn development, is expressed in nociceptive dorsal horn neurons and that its deletion results in the

98 rtate (NMDA)-induced activity in spinal cord dorsal horn neurons and that this enhancement is importa

99 ly sufficient for noxious heat activation of dorsal horn neurons and that, despite their polymodal pr

100 8 act upstream from Erk activation in spinal dorsal horn neurons and the calcium-AC1/AC8-dependent Er

101 o determine the changes in synaptic input to dorsal horn neurons and the GABAB)receptor function in s

102 a(+) channel within second-order spinal cord dorsal horn neurons and third-order thalamic neurons alo

103 es between the KA receptors expressed by rat dorsal horn neurons and those expressed by the primary a

104 ) contributes to the responsiveness of these dorsal horn neurons and to pain-related behaviors.

105 g in the primary sensory neurons, the spinal dorsal horn neurons, and astrocytes.

106 reduced hyperexcitability of multireceptive dorsal horn neurons, and attenuated mechanical allodynia

107 protein, reduced the hyperresponsiveness of dorsal horn neurons, and attenuated pain-related behavio

108 zed by bilateral hyperexcitability of lumbar dorsal horn neurons, and behavioral signs of central pai

109 us stimuli activate overlapping ensembles of dorsal horn neurons, and that stimulus type and intensit

110 hreshold neurons, but not wide dynamic-range dorsal horn neurons, and why it may not be effective in

111 m-chloride cotransporter KCC2 in spinal cord dorsal horn neurons are a major contributor to the centr

112 strongly suggest that NR1 subunits in spinal dorsal horn neurons are phosphorylated following CAP inj

113 nd physiological properties of glutamatergic dorsal horn neurons are poorly characterized despite the

114 erentiation and migration of the superficial dorsal horn neurons are regulated by the LIM homeobox ge

115 at less than 20% of superficial Tacr1(CreER) dorsal horn neurons are spinal projection neurons, and t

116 n of Nav1.3 protein and hyperexcitability in dorsal horn neurons as well as pain-related behaviors re

117 that cholinergic boutons are presynaptic to dorsal horn neurons as well as to the terminals of senso

118 eripheral terminals of the nociceptor and in dorsal horn neurons, as well as later transcription-depe

119 cient to evoke action potentials in neonatal dorsal horn neurons but was accompanied by a block of EP

120 mouse has abundant expression in superficial dorsal horn neurons, but not in the DRG.

121 the SSC will inhibit the activity of spinal dorsal horn neurons by activating the descending inhibit

122 n results in the specific loss of excitatory dorsal horn neurons by apoptosis, without any effect on

123 Preventing nerve injury-induced apoptosis of dorsal horn neurons by blocking caspase activity maintai

124 Activity induced in dorsal horn neurons by ionophoresing various mGluR subgr

125 can trigger activation of silent synapses in dorsal horn neurons by recruiting AMPA receptors.

126 ion of hyperexcitability of nociceptive deep dorsal horn neurons by TNF-alpha largely depends on the

127 Extracellular recording has shown that dorsal horn neurons can have an inhibitory surround outs

128 pain behavior reflecting hypersensitivity of dorsal horn neurons (central sensitization).

129 ts in a change in the excitability of spinal dorsal horn neurons, central sensitization, and the beha

130 ion of synaptically coupled DRG cells in DRG-dorsal horn neuron cocultures.

131 g from single wide dynamic range-type spinal dorsal horn neurons confirmed the descending nociceptive

132 Importantly, wide dynamic-range dorsal horn neurons continued to faithfully encode A-noc

133 spared nerve injury, the cumulative loss of dorsal horn neurons, determined by stereological analysi

134 fect of footshock on responses of 283 spinal dorsal horn neurons (DHNs) to urinary bladder distension

135 on induces synaptic GluR2 internalization in dorsal horn neurons during the maintenance of CFA-evoked

136 erlapping synaptic mechanisms in superficial dorsal horn neurons either by increasing excitatory syna

137 of evoked NMDAR-EPSCs and NMDAR currents of dorsal horn neurons elicited by puff NMDA application.

138 density in motoneurons to the level found in dorsal horn neurons eliminated selective motoneuron vuln

139 To characterize the subtypes of dorsal horn neurons engaged by dopamine signaling in the

140 s increases in spinal cord tissue and spinal dorsal horn neurons, especially in STT cells, after inje

141 excitatory postsynaptic currents (EPSCs) of dorsal horn neurons evoked by dorsal root stimulation in

142 excitatory postsynaptic currents (EPSCs) of dorsal horn neurons evoked by dorsal root stimulation.

143 ponses of superficial and deep lumbar spinal dorsal horn neurons evoked by mechanical and heat stimul

144 In addition, kainate suppressed EPSCs in dorsal horn neurons evoked by stimulation of synapticall

145 c excitatory postsynaptic currents of spinal dorsal horn neurons evoked from the dorsal root.

146 50 and 100 microg) on the responses of deep dorsal horn neurones, evoked by peripheral electrical st

147 receptors (GlyRs) play a role in control of dorsal horn neuron excitability, their relative contribu

148 at least two different populations of spinal dorsal horn neurons exist which encode for a stimulus of

149 e flexion reflex EMG activity and individual dorsal horn neuron firing properties, from excitation to

150 ordings were made from individual convergent dorsal horn neurones following electrical and natural (m

151 hanges in response properties of nociceptive dorsal horn neurons following implantation of fibrosarco

152 cluded that the inhibition of multireceptive dorsal horn neurones from GiA is dynamically activated b

153 ssed, prevents a significant portion of deep dorsal horn neurons from becoming sensitized to C-fiber

154 iation of glycine-activated current in mouse dorsal horn neurons from spinal cord slices.

155 Here we show that in spinal dorsal horn neurons >80% of mGluR5 is intracellular, of

156 in embryonic dorsal root ganglion (DRG) and dorsal horn neurons, has a role in the development of se

157 elta- and C-fibre evoked responses of spinal dorsal horn neurones in a dose related manner.

158 Whole-cell recordings of dorsal horn neurones in postnatal rat slices revealed th

159 mediated post-discharge responses of spinal dorsal horn neurones in spinal nerve ligated rats is rep

160 on, we performed intracellular recordings of dorsal horn neurones in spinal slices from adult mice.

161 upon the electrophysiological properties of dorsal horn neurones in the adult spinal cord via intera

162 SP) were tested on a sample (n = 50) of deep dorsal horn neurones in the isolated and hemisected youn

163 es on the electrophysiological properties of dorsal horn neurones in the rat adult spinal cord.

164 nflammatory concentrations, activated spinal dorsal horn neurons in a dose-dependent manner, as measu

165 vestigate if these mediators activate spinal dorsal horn neurons in a manner consistent with itch.

166 erent (CPSA) fibers were determined on C1-C3 dorsal horn neurons in anaesthetized rats.

167 In rats, dorsal horn neurons in C1-C2 segments receive phrenic in

168 s thought to have a role in sensitization of dorsal horn neurons in certain pain states, and a recent

169 s been shown to be synaptically localized on dorsal horn neurons in culture and expressed by dorsal h

170 eceptors in the control of synaptic input to dorsal horn neurons in diabetes remains poorly understoo

171 preparations and patch-clamp recordings from dorsal horn neurons in lamina V of the rat spinal cord,

172 dynamic range (WDR) and high threshold (HT) dorsal horn neurons in mice with tumor-evoked hyperalges

173 predominantly attenuates GABAergic inputs to dorsal horn neurons in mice, an action that is opposite

174 tivation of non-NMDA receptors in the spinal dorsal horn neurons in neuropathic pain conditions.

175 ary sensory neurons and nociceptive input to dorsal horn neurons in neuropathic pain.

176 nal cord mu-opioid receptor (MOR)-expressing dorsal horn neurons in nociception and morphine analgesi

177 tsynaptic currents (EPSCs) were performed on dorsal horn neurons in rat spinal cord slices.

178 significantly potentiate glycine currents in dorsal horn neurons in rat spinal cord slices.

179 thresholds of lamina IV-V wide dynamic-range dorsal horn neurons in response to both A- and C-nocicep

180 show that mGluR1 and mGluR5 are activated in dorsal horn neurons in response to peripheral inflammati

181 protein kinases are activated in spinal cord dorsal horn neurons in response to stimulation of nocice

182 sal horn neurons in culture and expressed by dorsal horn neurons in situ.

183 synaptic excitatory postsynaptic currents of dorsal horn neurons in SNL rats.

184 patch-clamp recordings from rat superficial dorsal horn neurons in spinal cord slices at postnatal d

185 Finally, in recordings from dorsal horn neurons in spinal slices, kainate and ATPA w

186 of physiologically characterized superficial dorsal horn neurons in the barbiturate-anesthetized cat

187 lamp recordings were performed on visualized dorsal horn neurons in the lamina II in the spinal cord

188 rd, therefore, produce inhibitory effects on dorsal horn neurons in the lumbar spinal cord that recei

189 compare activity of the same single, spinal dorsal horn neurons in the physiologically intact, awake

190 pain transmission by measuring activation of dorsal horn neurons in the spinal cord in response to no

191 m between some primary sensory afferents and dorsal horn neurons in the spinal cord.

192 ronal-restricted precursor cells that become dorsal horn neurons in the superficial laminae.

193 WDR, but not HT, nociceptive dorsal horn neurons in tumor-bearing mice exhibited sens

194 amplitude of miniature EPSCs in superficial dorsal horn neurons in vitro.

195 study examines the functional connections of dorsal horn neurons in young and adult rats that have un

196 een shown that systemic morphine can inhibit dorsal horn neurons independent of the descending system

197 The differing effects of ice and icilin on dorsal horn neurones indicate different mechanisms of ac

198 -regulated kinase in superficial spinal cord dorsal horn neurons, indicative of central sensitization

199 plex, and central sensitization of medullary dorsal horn neurons is a critical factor in muscle hyper

200 hat neurotransmitter release from inhibitory dorsal horn neurons is affected by activation of presyna

201 known as to whether synaptic input to spinal dorsal horn neurons is altered in diabetic neuropathy.

202 d that responsiveness of multireceptive (MR) dorsal horn neurons is dramatically increased at 28 days

203 n processed in individual wide dynamic-range dorsal horn neurons is modulated by prostanergic descend

204 We examined three different populations of dorsal horn neurons; lamina I NK1R+ neurons, including p

205 P) recordings were obtained from spinal cord dorsal horn neurons (laminae I-IV) in a rat transverse s

206 brane depolarization in the majority of deep dorsal horn neurons (laminas III-VI; 83 of 139 cells), b

207 abeled only about 5% of the normal number of dorsal horn neurons, mainly in lamina IV, below the leve

208 urokinin 1 (NK1) receptor expressing (NK1R+) dorsal horn neurons, many of which are projection neuron

209 okinin 1 (NK1) receptor expressing (NK1R(+)) dorsal horn neurons, many of which are projection neuron

210 s, whereas widespread PV immunoreactivity in dorsal horn neurons marks the attainment of a mature pat

211 s between primary afferent fibres and spinal dorsal horn neurons may be inefficient or silent.

212 lutamatergic input from primary afferents to dorsal horn neurons may contribute to synaptic plasticit

213 s of normal function in parvalbumin positive dorsal horn neurons may result in the development of tac

214 fibers and the spinal cord, activate Erk in dorsal horn neurons of both adult rat and mouse spinal c

215 Spinal L6-S2 dorsal horn neurons of cervical spinal cord-transected,

216 PSCs and the frequency of miniature EPSCs in dorsal horn neurons of FK506-treated rats.

217 Whole-cell patch clamp recordings from dorsal horn neurons of neonatal rat spinal cord slices w

218 ular recordings from mechanonociceptive deep dorsal horn neurons of normal rats in vivo, we found tha

219 rents (EPSCs) were recorded from superficial dorsal horn neurons of spinal slices taken from young ad

220 we made extracellular recordings from lumbar dorsal horn neurons of the mouse in response to graded t

221 e) MAP (mitogen-activated protein) kinase in dorsal horn neurons of the spinal cord by peripheral nox

222 Hyperactivity of spinal dorsal horn neurons plays an important role in the devel

223 radykinin, by activating multiple kinases in dorsal horn neurons, potentiates glutamatergic synaptic

224 Blocking the Wnt5a-Ryk/Ror2 axis in spinal dorsal horn neurons prevented activity-dependent dendrit

225 d, as nothing is known about how superficial dorsal horn neurons process sensory input from muscle ve

226 c afferents actively modulates thoracolumbar dorsal horn neuron processing of the same colonic stimul

227 er suggest that some lumbosacral superficial dorsal horn neurons project to the upper cervical dorsal

228 Many of these second-order dorsal horn neurons project to third-order neurons in th

229 of the serotonin receptor 2A (5-HT(2A)R) in dorsal horn neurons promotes spinal hyperexcitation and

230 Following neonatal carrageenan inflammation, dorsal horn neuron properties and receptive field sizes

231 s co-released with GABA from some inhibitory dorsal horn neurons raising the possibility that ATP cou

232 region (MLR) inhibited the discharge of deep dorsal horn neurons receiving group III afferent input f

233 ptive area for monosynaptic projections from dorsal horn neurons receiving sensory afferent inputs.

234 Enlarged dorsal horn neuron receptive field sizes provide a physi

235 rons and excitatory synaptic transmission in dorsal horn neurons, reduced meningeal blood flow, reduc

236 These findings demonstrate that some dorsal horn neurons release opioids when they fire at hi

237 lecular identity and function in spinal cord dorsal horn neurons remain elusive.

238 Since many PPD-expressing dorsal horn neurons respond to noxious stimulation, this

239 ere sensitive to both kainate and ATPA, most dorsal horn neurons responded only to kainate.

240 nd, and at times, opposite effects on spinal dorsal horn neuron responses to non-noxious and noxious

241 -type currents and increases excitability of dorsal horn neurons, resulting in enhanced sensitivity t

242 Dorsal horn neurons showed PRV-IR by 4.5 days.

243 Dorsal horn neurons showing excitatory responses to colo

244 ranscriptional changes in superficial spinal dorsal horn neurons (SSDHN) are essential in the develop

245 - to threefold higher in motoneurons than in dorsal horn neurons, suggesting a higher density of func

246 to enhance the frequency of EPSCs in spinal dorsal horn neurons, suggesting an increased excitatory

247 in vivo potentiates glycinergic synapses on dorsal horn neurons, suggesting that GlyR LTP is trigger

248 lutamatergic synaptic transmission in 59% of dorsal horn neurons tested, and this effect was blocked

249 ive abundance of GluR2 varied more widely in dorsal horn neurons than in motoneurons, but the mean va

250 properties of NMDA receptor channels in rat dorsal horn neurones that receive sensory inputs from an

251 l coding and central sensitization of deeper dorsal horn neurons that are important for both pain sen

252 iniature excitatory postsynaptic currents in dorsal horn neurons that could be blocked by gabapentin.

253 on cause a caspase-dependent degeneration of dorsal horn neurons that is slow in onset and persists f

254 e activity of second-order trigeminovascular dorsal horn neurons that receive peripheral input from t

255 her ablation procedure reduced the number of dorsal horn neurons that responded to noxious cold.

256 to an increase in the excitability of spinal dorsal horn neurons that results from, and far outlasts

257 We report that CCL21 is upregulated in dorsal horn neurons, that tissue levels are increased in

258 rons in primary afferents and in superficial dorsal horn neurons, there is little to no information a

259 atS from microglia, which liberates FKN from dorsal horn neurons, thereby contributing to the amplifi

260 reduces the glutamatergic synaptic input to dorsal horn neurons through GABA(B) receptors.

261 NO enhances inhibitory glycinergic input to dorsal horn neurons through sGC-cGMP-protein kinase G.

262 long-term activation of spinal cord glia and dorsal horn neurons, thus resulting in central sensitiza

263 nist, ketanserin, on the evoked responses of dorsal horn neurones to electrical, mechanical and therm

264 study, the responses of single lamina III-V dorsal horn neurons to an innocuous A beta fibre brush s

265 ted the excitatory response of thoracolumbar dorsal horn neurons to colorectal distention (CRD) and d

266 this study, the response of the spinal cord dorsal horn neurons to graded heat stimuli were characte

267 t inhibition of the responses of spinal cord dorsal horn neurons to higher intensity mechanical stimu

268 t inhibition of the responses of spinal cord dorsal horn neurons to higher intensity mechanical stimu

269 The response of the spinal cord dorsal horn neurons to mechanical stimuli are classified

270 subsets of primary afferents and superficial dorsal horn neurons to reduce both primary afferent sens

271 The prolonged responses of superficial dorsal horn neurons to SLIGRL-NH(2) and 5-HT suggest a r

272 o determine the responses of the spinal cord dorsal horn neurons to stimulation of the primary somato

273 ibution of plasticity in primary sensory and dorsal horn neurons to the pathogenesis of pain, identif

274 excitatory and inhibitory synaptic inputs to dorsal horn neurons using whole-cell recordings in rat s

275 ory synaptic inputs to mouse lamina I spinal dorsal horn neurons, using laser scanning photostimulati

276 acid (NMDA) receptor hyperactivity in spinal dorsal horn neurons via inhibition of the extracellular

277 urrents elicited by puff NMDA application to dorsal horn neurons was also significantly greater in FK

278 odulation of inhibitory transmission between dorsal horn neurons was preserved in cells from either G

279 y of spontaneous and miniature EPSCs in most dorsal horn neurons was profoundly increased in FK506-tr

280 In contrast, nNOS staining in dorsal horn neurons was unaltered by these manipulations

281 and patch-clamp recordings from spinal cord dorsal horn neurons, we examined excitatory and inhibito

282 sion between dorsal root ganglia neurons and dorsal horn neurons, we reconstructed the first pain syn

283 m-sap) to selectively destroy MOR-expressing dorsal horn neurons, we sought to determine the role of

284 KN immunoreactivity and mRNA are confined to dorsal horn neurons, we suggest that under neuropathic c

285 underlying this sensitization of superficial dorsal horn neurons, we undertook a genome-wide microarr

286 s of electrically evoked responses of spinal dorsal horn neurones were made in halothane anaesthetise

287 d CREB in both ipsilateral and contralateral dorsal horn neurons were dramatically reduced in antisen

288 Dorsal horn neurons were found to be synaptically driven

289 Spinal motoneurons and dorsal horn neurons were isolated from embryonic rats an

290 Thirty-four wide dynamic range spinal dorsal horn neurons were recorded in response to graded

291 Dorsal horn neurons were recorded in the rat thoracolumb

292 Thirty-two wide dynamic range spinal dorsal horn neurons were recorded, in response to graded

293 es 1 (AC1) and 8 (AC8), activation of Erk in dorsal horn neurons were significantly reduced or blocke

294 n in KA receptor-mediated current density in dorsal horn neurons, whereas GluR5 deletion caused no ch

295 n of prodynorphin and neurokinin-1 (NK-1) in dorsal horn neurons, which was suppressed by intrathecal

296 le-unit recordings were made from L4-L5 deep dorsal horn neurons (wide dynamic range and nociceptive

297 B(2) receptors are coexpressed in dorsal horn neurons with protein kinase A (PKA) and the

298 Dorsal horn neurons with stronger C-nociceptor input wer

299 e cluster were depressed in both ventral and dorsal horn neurons within 24 h after injury, followed b

300 that altering the activity of MOR-expressing dorsal horn neurons would be antinociceptive and of inte