ライフサイエンスコーパス: dose-response relationship

1 20/40, and topical corticosteroid use (in a dose-response relationship).

2 l fMRI activity was weak or strong (U-shaped dose-response relationship).

3 ive therapy, and with evidence of a positive dose-response relationship.

4 ciated with an elevated risk of suicide in a dose-response relationship.

5 er tested characteristics did not modify the dose-response relationship.

6 and (2) evaluate potential modifiers of the dose-response relationship.

7 ction, and handwashing; evidence suggested a dose-response relationship.

8 indings suggesting a threshold rather than a dose-response relationship.

9 overy approaches commonly assume a monotonic dose-response relationship.

10 izophrenic prodrome and demonstrates a clear dose-response relationship.

11 lity, with a non-significant trend towards a dose-response relationship.

12 r pain and sciatica in men and women, with a dose-response relationship.

13 There was also evidence of a dose-response relationship.

14 This constitutes a robust absorbed dose-response relationship.

15 analysis with secondary analysis exploring a dose-response relationship.

16 eclinical internal radiotherapy to study the dose-response relationship.

17 termediate fluoridation exposure suggested a dose-response relationship.

18 he main determinants of ERT, with a definite dose-response relationship.

19 usibility was supported by the presence of a dose-response relationship.

20 es increased the risk of mood disorders in a dose-response relationship.

21 relationship was fairly linear, suggesting a dose-response relationship.

22 l cortical neurons with an inverted U-shaped dose-response relationship.

23 ciation; 25 assessed and found evidence of a dose-response relationship.

24 ROS production but with an inverted U-shaped dose-response relationship.

25 : HR, 0.84 [95% CI, 0.71 to 0.99]) without a dose-response relationship.

26 w patient numbers-would not prove a positive dose-response relationship.

27 fference in 5-y absolute risk), with a clear dose-response relationship.

28 ironmental pathogens and infection, i.e. the dose-response relationship.

29 Larger studies are needed to estimate true dose response relationships.

30 spitalized with infection in prospective and dose-response relationships.

31 SARS-CoV-2, including 21 drugs that exhibit dose-response relationships.

32 linical trials, and we were unable to detect dose-response relationships.

33 ) that can quantitatively predict antibiotic dose-response relationships.

34 t disease, thrombotic stroke, and COPD, with dose-response relationships.

35 and sunlamp use, but we found no significant dose-response relationships.

36 provided unstable estimates and inconsistent dose-response relationships.

37 sion models to test the linear and nonlinear dose-response relationships.

38 f nose-to-brain oxytocin routes and possible dose-response relationships.

39 ricted cubic spline regression characterized dose-response relationships.

40 chemotherapy-associated SMN risk, including dose-response relationships.

41 stricted cubic spline models to evaluate the dose-response relationships.

42 Based on target analysis, potency and dose-response relationships, 5 compounds were subsequent

43 ropose a nonparametric model to describe the dose response relationship and fit the curve using local

44 ption of network organization, reflecting a "dose response" relationship and emphasize the role of ef

45 The association exhibits a dose-response relationship and is strongest for death fr

46 f this study was to investigate the absorbed dose-response relationship and its association with over

47 o the representation of the Western hormetic dose-response relationship and review the Yin/Yang histo

48 ight of ten causality dimensions (all except dose-response relationship and specificity), we found th

49 esity is mediated by time, insights into the dose-response relationship and the cumulative impact of

50 erated very consistent results and evinced a dose-response relationship and therefore represents an u

51 The association demonstrated a dose-response relationship and was stronger (more than 2

52 Use of antibiotics (supported by the dose-response relationship) and gastrointestinal infecti

53 exhibited encouraging activity but no clear dose-response relationship, and few patients had aggress

54 se II trial assessed the antitumor activity, dose-response relationship, and safety of nivolumab in p

55 rability of transgene expression, the vector dose-response relationship, and the level of persistent

56 hat better delineation of sensitive periods, dose-response relationships, and long-term longitudinal

57 te target engagement, differential efficacy, dose-response relationships, and prediction of clinicall

58 iation, alternative explanations, cessation, dose-response relationship, animal experiments, analogy,

59 The better dose-response relationship appeared to be the one based

60 nts who have more than 1 complication with a dose-response relationship as complications accrue.

61 The primary objective was to evaluate the dose-response relationship as measured by progression-fr

62 The absence of a dose-response relationship based on breastfeeding durati

63 nges in cardiac output (CO); (2) a potential dose-response relationship between 3-OHB levels and CO;

64 A dose-response relationship between adherence and HIV tra

65 Available data suggest that the dose-response relationship between allergen exposure and

66 To examine whether a continuous, dose-response relationship between amyloid burden and co

67 e objective of this study was to examine the dose-response relationship between As and global methyla

68 There was an inverse U-shaped dose-response relationship between attained sphenopalati

69 e studies should be conducted to clarify the dose-response relationship between beta-carotene and all

70 A strong significant and positive dose-response relationship between BMI and current asthm

71 idney disease (CKD) and explored a potential dose-response relationship between bone loss and CKD-rel

72 dle-income country: there was a differential dose-response relationship between childhood maltreatmen

73 coronary heart disease at baseline, a strong dose-response relationship between cigarette smoking and

74 We have found a dose-response relationship between COPD duration and ris

75 d parietal cortical thinning, and an inverse dose-response relationship between CPF and cortical thic

76 r, further studies are needed to clarify the dose-response relationship between different subtypes an

77 There was evidence of a dose-response relationship between duration of bicycling

78 We hypothesized a dose-response relationship between duration of football

79 In the population, there was a dose-response relationship between early gestation and t

80 We observed a strong dose-response relationship between ECG abnormalities and

81 dditional evidence is needed to evaluate the dose-response relationship between environmental arsenic

82 There is a strong dose-response relationship between events known to resul

83 ining the body of literature that supports a dose-response relationship between exercise and cardiova

84 We observed evidence of a positive, dose-response relationship between fast food intake and

85 However, there was no evidence of a dose-response relationship between frequency of use and

86 ies to clarify the strength and shape of the dose-response relationship between general and abdominal

87 there is uncertainty about the nature of the dose-response relationship between HFSS advertising and

88 There was a consistent dose-response relationship between higher proportional b

89 We detected a dose-response relationship between increased prenatal PA

90 This meta-analysis suggests a dose-response relationship between infused albumin and s

91 inate friendliness and that there might be a dose-response relationship between institutional rearing

92 Modeling of a nonlinear dose-response relationship between IR-induced DSBs and C

93 There was a dose-response relationship between length of residence i

94 clearly and accurately depict the well-known dose-response relationship between light intensity and p

95 subjects with gout, there was a significant dose-response relationship between mean temperature in t

96 Preliminary evidence suggests a dose-response relationship between metformin use and inc

97 tients who had no complications, there was a dose-response relationship between mortality and the num

98 There is an inverse dose-response relationship between PA and HF risk.

99 There was a significant dose-response relationship between pack-years of smoking

100 The dose-response relationship between plasma lead and M/P r

101 Spline regression showed a dose-response relationship between PM2.5 levels and COWO

102 We observed a strong dose-response relationship between porewater Cu and H. a

103 A clear dose-response relationship between quintiles of suppleme

104 We also estimated the dose-response relationship between receipt of increasing

105 k for subsequent new SCC but not BCC, with a dose-response relationship between risk and lower CD4 co

106 Nevertheless, there was a dose-response relationship between RNFL thinning and num

107 May 2014 in which investigators assessed the dose-response relationship between serum levels of 2,3,7

108 The dose-response relationship between serum TCDD and DM acr

109 A dose-response relationship between statin use and HCC ri

110 There was a dose-response relationship between statin use and the ri

111 Describe the dose-response relationship between step count and intens

112 cubic spline method was used to estimate the dose-response relationship between SUA and fundus arteri

113 study among Finnish adults suggest a linear dose-response relationship between sugars and caries, wi

114 Our data provide evidence for a dose-response relationship between tanning bed use and t

115 There was a dose-response relationship between tertiles of telomere

116 There is evidence for a dose-response relationship between the amount of mesh us

117 almitic acid with oleic acid; evidence for a dose-response relationship between the intake of dietary

118 Among NDM patients, there was a dose-response relationship between the level of BG and c

119 We noted a strong dose-response relationship between the lowest-yield cate

120 There was a positive dose-response relationship between the number and durati

121 A dose-response relationship between the number of adverse

122 A dose-response relationship between the number of chronic

123 ty regardless of BMI levels, and there was a dose-response relationship between the number of inciden

124 There is a dose-response relationship between the number of postope

125 There was a dose-response relationship between the number of psychos

126 There was a significant dose-response relationship between the number of reflux

127 There was a strong dose-response relationship between the number of risk al

128 Quantitative analyses show a log-linear dose-response relationship between the sucrose or its mo

129 ant agents suppress REM sleep and a time-and-dose-response relationship between total REM sleep suppr

130 ting that ribosomal biogenesis regulates the dose-response relationship between training volume and m

131 There was a significant positive dose-response relationship between uncontrolled hyperten

132 There was a dose-response relationship between weekend nurse/bed rat

133 ralized additive models were used to examine dose-response relationships between blood, plasma, and m

134 iovascular mortality and highly inconsistent dose-response relationships between calcium intake and r

135 We explored the dose-response relationships between maternal blood, plas

136 addition, we observed significantly positive dose-response relationships between number of nevi and h

137 Categorical dose-response relationships between PA and HF risk were

138 testing positive for SARS-CoV-2 with strong dose-response relationships between several forms of mov

139 Cohort studies showed no consistent dose-response relationships between total, dietary, or s

140 the degree of blast exposure, suggesting a 'dose-response' relationship between the number of blast

141 ses a much more pronounced left shift of the dose-response relationship by increasing its affinity to

142 Hormesis is a generalizable dose-response relationship characterized by low-dose sti

143 atients with HFpEF, there was no significant dose-response relationship detected for neladenoson with

144 hods for bone marrow dosimetry and study the dose-response relationship during treatment with (177)Lu

145 wo dogs developed food allergy, suggesting a dose-response relationship (each dog owned aOR 0.12 (CI

146 etic responses are characterized as biphasic dose-response relationships exhibiting a low-dose stimul

147 aim of the study was to determine whether a dose-response relationship exists between cumulative run

148 esviruses are also implicated, nor whether a dose-response relationship exists between tuberculosis r

149 A strong dose-response relationship exists for the treatment of C

150 The choice of dose response relationship for physical activity had a l

151 biomedical data that exhibits a nonmonotonic dose response relationship for which traditional paramet

152 nd products, it is necessary to quantify the dose-response relationship for a wide range of doses for

153 The dose-response relationship for BMI with HFpEF risk was a

154 tivity approach, a statistically significant dose-response relationship for both thyroid remnants and

155 The dose-response relationship for CRF on EDS performance re

156 Is there a dose-response relationship for efficacy and safety?, and

157 tments and lysosomes alongside a PTH-induced dose-response relationship for fractional phosphate excr

158 g hypo- and hyperglycemia, respectively, the dose-response relationship for glucose-induced [ATP]pm g

159 at model of acute myocardial infarction, the dose-response relationship for intracoronary CSCs is fla

160 We found a dose-response relationship for mGFP-GPI nanoplatform dis

161 set (IRR = 1.24, 95% CI: 1.07, 1.43), with a dose-response relationship for number of courses (P-tren

162 aim of the present work was to evaluate the dose-response relationship for pancreatic neuroendocrine

163 There was no significant dose-response relationship for the change in 6-minute wa

164 uccessfully describe experimentally observed dose-response relationships for a variety of cell types.

165 Dose-response relationships for alkylating chemotherapy

166 ing safety of nonalkylating chemotherapy and dose-response relationships for alkylating chemotherapy

167 d population dose responses are distinct; b) dose-response relationships for all (including quantal)

168 tems, (b) improving environmentally relevant dose-response relationships for different organisms and

169 These are treatment modalities for which dose-response relationships for healthy tissues and tumo

170 We performed NTCP-modeling and established dose-response relationships for visual acuity (VA) deter

171 mall increase in risk, with no evidence of a dose-response relationship (for fourth vs. first quartil

172 cancer was near null, with no evidence of a dose-response relationship (for fourth vs. first quartil

173 With other CD20 antibodies, a dose-response relationship has been shown.

174 activity may still be suboptimal, because a dose-response relationship has not been defined.

175 risks of heart failure (HF), but a radiation dose-response relationship has not previously been deriv

176 work characterizing the functional forms of dose-response relationships has used statistical fit to

177 dings from current knowledge of radiological dose-response relationships, here mammal response in ter

178 The linear radiation dose-response relationship identified can be used to pre

179 These results confirm a significant absorbed dose-response relationship in (166)Ho radioembolization.

180 The dose-response relationship in a fixed-activity approach

181 The lack of a dose-response relationship in both the efficacy and safe

182 Conclusion: A significant dose-response relationship in CRC patients treated with

183 r clinical trials of vericiguat based on the dose-response relationship in this study are needed to d

184 ay afford insights that clarify the hormetic dose-response relationship in toxicology and pharmacolog

185 For chlorophyll, there were better dose-response relationships in Chlorococcum sp., Chlamyd

186 conditions and a meta-analysis that found a "dose-response relationship" in observational studies of

187 A dose-response relationship indicated higher IQ scores in

188 In regulatory toxicology, the dose-response relationship is a key element towards fulf

189 model calculations presented in this work, a dose-response relationship is demonstrated, and an analy

190 ediated by oxytocin; and that in females the dose-response relationship is initiated at lower doses c

191 MDS in both males and females, and that this dose-response relationship is initiated at lower doses i

192 choice, yet information on the nature of the dose-response relationship is lacking.

193 As this dose-response relationship is observed across hospitals,

194 A dose-response relationship is suggested with respect to

195 tion, the complexity of exposure and dose in dose-response relationships is highlighted.

196 Although exploratory, a dose-response relationship may exist, but its relevance

197 cient, nH, which measures the steepness of a dose-response relationship, may be a useful gauge of thi

198 A significant dose-response relationship (multiple comparison procedur

199 To estimate this value, the dose response relationship needs to be established, whic

200 CM-HIPK2 heterozygous mice exhibited a gene dose-response relationship of CM-HIPK2 on heart function

201 A dose-response relationship of compounds 1-4 was determin

202 Nevertheless, there is debate on the dose-response relationship of exercise and cardiovascula

203 with the currently available evidence of the dose-response relationship of ICS in adult asthma.

204 review to establish an understanding of the dose-response relationship of intrathecal GBCAs and to c

205 The authors explored the dose-response relationship of ivabradine in children wit

206 A meta-analysis was performed to assess the dose-response relationship of long-term coffee consumpti

207 e purpose of this study was to establish the dose-response relationship of selective internal radiati

208 ffects models to model any alcohol intake or dose-response relationships of alcohol intake and cardio

209 The dose-response relationships of antipsychotic drugs for s

210 ummarize available data on the dosimetry and dose-response relationships of several theranostic compo

211 Dose-response relationships of sodium, chloride, potassi

212 Although we did not observe a dose-response relationship on absolute changes in [tissu

213 l artery was not sufficient to yield a clear dose-response relationship on NE content and axon densit

214 in death; however, little is known about the dose-response relationship or effects of potential overd

215 harmacological profile without a bell-shaped dose-response relationship or tachyphylaxis in preclinic

216 The associations fitted a dose-response relationship (p < .001) and remained signi

217 A significant dose-response relationship (p = .0022) was observed acro

218 shorter LTLs, respectively, with evidence of dose-response relationship (P for trend < 0.05).

219 s rose with increasing levels of stress in a dose-response relationship (P-trend < 0.0001), independe

220 of topical (aHR, up to 8.77 that followed a dose-response relationship; P < 0.001), periocular (aHR,

221 There was also a significant pitrakinra dose-response relationship (placebo/1 mg/3 mg/10 mg) for

222 ries of protocols to assess its methacholine dose-response relationship, shortening velocity, and res

223 ation in seven of ten dimensions (all except dose-response relationship, specificity, and animal expe

224 g them suitable for quantitative imaging and dose-response relationship studies in animals.

225 We found a dose-response relationship such that individuals with CO

226 ared with nonobese patients, and there was a dose-response relationship such that obese (odds ratio =

227 There was evidence of a dose-response relationship such that the effect of age o

228 There were dose-response relationships such that a greater number o

229 ath or ventricular arrhythmia, the lack of a dose-response relationship suggests that this associatio

230 NE in the OB generated a non-monotonic dose-response relationship, suppressing mitral cell acti

231 and the number of injections had a nonlinear dose-response relationship that became apparent after ap

232 de a more sophisticated understanding of the dose-response relationship, the integration of genetic a

233 To determine dose-response relationships, the association between smo

234 luenced by the microinjections in a biphasic dose-response relationship; the lowest (0.3mug) and high

235 MACE was associated with a dose-response relationship to the number of vessels exhi

236 diates UV-B responses in vivo with a similar dose-response relationship to wild-type.

237 o contaminants and nutrients in fish, employ dose-response relationships to convert exposure to healt

238 ic studies should focus on the evaluation of dose-response relationships, types of solid cancers, lat

239 high resolution of the data reveals complex dose-response relationships unambiguously.

240 through reevaluation of the lead absorption dose-response relationship using new bioavailability dat

241 maximal change, change magnitude, and gluten dose-response relationship varied.

242 The absorbed dose-response relationship was assessed using a linear m

243 Furthermore, for L. innocua, the dose-response relationship was demonstrated and found to

244 A significant dose-response relationship was demonstrated between chro

245 No dose-response relationship was detected as measured by P

246 A dose-response relationship was evident at each measured

247 in each period independently, among boys, a dose-response relationship was evident for each level in

248 A clear dose-response relationship was evident.

249 We also expected to determine whether a dose-response relationship was evident.

250 A strong and statistically significant dose-response relationship was found (P < 0.001).

251 A dose-response relationship was found between the IOP PRS

252 A dose-response relationship was generated and the probabi

253 A dose-response relationship was identified between pack-y

254 rimental periodontitis, however, a potential dose-response relationship was not determined.

255 However, a dose-response relationship was not observed.

256 A dose-response relationship was observed between anthracy

257 xposures did not interact synergistically, a dose-response relationship was observed between domestic

258 No dose-response relationship was observed between GSK21417

259 A dose-response relationship was observed between longer D

260 A dose-response relationship was observed between severity

261 A dose-response relationship was observed for transient tu

262 A dose-response relationship was observed for upadacitinib

263 A dose-response relationship was observed with injury seve

264 In general, a dose-response relationship was observed, with the highes

265 A similar dose-response relationship was observed.

266 igned intent-to-treat patients at week 12, a dose-response relationship was observed; APR40 (n = 63),

267 With decreasing financial reserves, a clear dose-response relationship was present across all measur

268 A trend toward a dose-response relationship was seen for AC cells and fla

269 fections of the respiratory tract, whereas a dose-response relationship was seen for skin infections.

270 FB1) and proliferation of cells M12.C3.F6; a dose-response relationship was showed.

271 To study the dose-response relationship, we begin with the assumption

272 The absence of a dose-response relationship weakens causal interpretation

273 fects of dose and potential modifiers of the dose-response relationship were evaluated with hierarchi

274 Dose-response relationships were evaluated between cance

275 Dose-response relationships were modeled with restricted

276 currents, the current amplitudes, and the pH dose-response relationships were not altered in mice wit

277 Dose-response relationships were observed with respect t

278 ant exposure pathways, and pathogen-specific dose-response relationships were then used to estimate p

279 e exploratory secondary analysis suggested a dose-response relationship whereby higher vericiguat dos

280 on and frequency, cg05575921 showed a strong dose-response relationship, while there was evidence for

281 wever, additional research on the timing and dose-response relationship will be crucial for designing

282 Full dose response relationships with inductions over 100-fol

283 to the total set of QIs showed a significant dose-response relationship with a shorter LOS.

284 There was a dose-response relationship with a significant CO increas

285 rability to developing PTSD or the lack of a dose-response relationship with amygdala volume.

286 y measure of DBPs that yielded the strongest dose-response relationship with bladder cancer risk.

287 In models examining TDP-43 stage, a dose-response relationship with clinical Alzheimer's-typ

288 indicated that advancing paternal age had a dose-response relationship with every index of morbidity

289 uld respond, as evidenced by the significant dose-response relationship with ICS adherence.

290 Exposure to benzodiazepines showed a dose-response relationship with mortality (hazard ratios

291 FGF23 exhibited a dose-response relationship with outcomes (HR=1.30 per do

292 SAR236553 demonstrated a clear dose-response relationship with respect to percentage LD

293 atal stress further demonstrated a positive, dose-response relationship with symptoms of externalizin

294 The risk of mental disorders increased in a dose-response relationship with the number of maternal i

295 A significant dose-response relationship with the prevalence and incid

296 placebo, and secondary analysis evaluated a dose-response relationship with vericiguat and the prima

297 d cause-specific mortality and elucidate the dose-response relationships with better quantification o

298 Ln-vanadium concentrations showed non-linear dose-response relationships with risk of preterm deliver

299 There was a dose response relationship, with increased odds ratios w

300 The dose-response relationship, with the 400 U dose showing