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1 ate of N-DRC and its attachment to the outer doublet microtubule.
2 the ODA-DC and the outer dynein arm onto the doublet microtubule.
3 e NDRC proximal lobe that binds the adjacent doublet microtubule.
4 -tubule along the length of all nine ciliary doublet microtubules.
5 uration of ODAs into a form that can bind to doublet microtubules.
6 RS2, and RS3, repeats every 96 nm along the doublet microtubules.
7 rdinate dynein arm activity and interconnect doublet microtubules.
8 ed within the A-tubule of the axonemal outer doublet microtubules.
9 ered by dynein ATPases associated with outer doublet microtubules.
10 proteins form crossbridges between the outer doublet microtubules.
11 e confirmed that basal bodies contain mostly doublet microtubules.
12 riven microtubule sliding between subsets of doublet microtubules.
13 hat the axonemal CKI is located on the outer doublet microtubules.
14 ike projections in the B tubule of the outer doublet microtubules.
15 ke in each 96-nm axoneme repeat on flagellar doublet microtubules.
16 tal part of axonemes before binding to outer doublet microtubules.
17 ectively associate with a subset of axonemal doublet microtubules.
18 sting of two central singlets and nine outer doublet microtubules.
19 ferent dynein isoforms on the surface of the doublet microtubules.
20 in the transition of triplet microtubules to doublet microtubules, a defect correlated with failure t
21 la functions as a linker between neighboring doublet microtubules, acts to stabilize the axonemal cor
22 a tether linking one I1 motor domain to the doublet microtubule and doublet-specific differences pot
24 on, which comprises part of the wall of each doublet microtubule and is composed of tubulin and three
25 The ciliary skeleton is made of peripheral doublet microtubules and a central pair (CP) with a dist
27 al striations in the B tubule of respiratory doublet microtubules and noncontinuous spirals in sperm
28 latory complex (N-DRC), which links adjacent doublet microtubules and regulates and coordinates the a
29 Most dramatically, the space between the doublet microtubules and the flagellar membrane contains
31 tektins, which form coiled-coil filaments in doublet microtubules and which are associated with basal
32 d spoke bases that facilitate docking to the doublet microtubules, and that inner dyneins connect dir
35 nvolves signal-induced severing of the outer doublet microtubules at a precise site in the transition
36 yoelectron microscopy and modeling to define doublet microtubules at near-atomic resolution, revealin
37 the linear array of axonemal dyneins to the doublet microtubule by directly interacting with the hea
40 ned the effect of tubulin acetylation on the doublet microtubule (DMT) in the cilia of Tetrahymena th
41 us with cilia) with axonemes containing nine doublet microtubules (DMTs) and two singlet microtubules
44 resolve the 96-nm modular repeat of axonemal doublet microtubules (DMTs) from both sperm flagella and
45 igh-resolution structures of native axonemal doublet microtubules (DMTs) from sea urchin and bovine s
46 (IFT) trains move bidirectionally along the doublet microtubules (DMTs) of the axoneme within the fl
47 sists of a 9-fold array of remarkably stable doublet microtubules (DMTs), along which motor proteins
48 rotubules (TMTs), the axoneme is composed of doublet microtubules (DMTs), meaning the cilium must con
52 hanism may mediate the severing of the outer doublet microtubules during Chlamydomonas deflagellation
53 motility require a radially arranged set of doublet microtubules, each decorated in repeating patter
58 We propose that CKI is anchored on the outer doublet microtubules in position to regulate flagellar d
59 2 genes in the pathway mediating assembly of doublet microtubules in the axoneme from triplet microtu
61 ction of thousands of dynein motors bound to doublet microtubules into a single propulsive waveform.
64 roteins establish the unique architecture of doublet microtubules, maintain coherent periodicities al
65 two types of human ciliary microtubule: the doublet microtubules of multiciliated respiratory cells
66 FAP50 is tightly associated with the outer doublet microtubules of the axoneme and appears not to b
67 r to result from defects in either the outer doublet microtubules or the outer arm docking structures
70 n network crosslinking the lumen of axonemal doublet microtubules, suggesting their roles in modulati
71 flagella have a conserved structure of nine doublet microtubules surrounding a central pair of micro
72 of axoneme architecture, a cylinder of nine doublet microtubules surrounding a central pair of singl
73 metric, with most particles located near the doublet microtubules that face the opposite basal body.
74 lutamylation mainly on the B-tubule of outer doublet microtubules, the site of force production by ci
75 Periodic densities were also observed inside doublet microtubules; these may contribute to doublet st
76 precisely reciprocal to dominant defects in doublet microtubules we observed in a previous study of
77 le distinguishing each one of the nine outer doublet microtubules, we systematically collected and re
78 ar transport, and bound to specific sites on doublet microtubules, where their activity facilitates m
79 the repeating structure of a native axonemal doublet microtubule, which reveals the identities, posit
80 veal how mechanoregulatory complexes dock to doublet microtubules with regular 96-nm periodicity and