ライフサイエンスコーパス: doubt

1 h no difference in subjective confidence (or doubt).

2 d to have been established beyond reasonable doubt.

3 a diverse set of human cancers is now beyond doubt.

4 mericans before admixture is also subject to doubt.

5 nt research that brings this assumption into doubt.

6 cy of risk adjustment in those studies is in doubt.

7 e between experimental treatments is open to doubt.

8 t their lack of toxicity in humans is not in doubt.

9 me periods, calling the former paradigm into doubt.

10 plausibility of these various hypotheses in doubt.

11 e need for confirmation of diagnosis when in doubt.

12 efficient neurotransmission has remained in doubt.

13 ill in question but whose effects are beyond doubt.

14 ompatibility can be proven beyond reasonable doubt.

15 al power has cast neuroscience findings into doubt.

16 yndrome (MFS) and BBE in cases of diagnostic doubts.

17 d risks of immunization may counteract these doubts.

18 fer from something more than occasional self-doubts.

19 bodies used to identify P2X7R raised further doubts.

20 flicting results in recent years have raised doubts.

21 arpa, 2012) in which graphene is without any doubt a forefront nanomaterial.

22 ), the American public expresses substantial doubt about both the anthropogenic cause and the level o

23 s rotations with various methods, we express doubt about Churchland et al.'s bold assessment that suc

24 If there is doubt about safety, the question arises of whether patie

25 his eligibility for organ donation and cast doubt about the ability to determine irreversibility of

26 nal connectivity studies on prosody leave no doubt about the existence of such streams, but opinions

27 data obtained from rodent models and raises doubt about the justification of resveratrol as a human

28 radually declined in recent years because of doubt about the long-term stability of molecular-catalys

29 abnormality and seem to remain stable, with doubt about the presence of underlying neurodegenerative

30 New work has raised some doubt about the protective effect of colonoscopy in the

31 lly interpreted as negative, thereby raising doubts about a potential causal association.

32 ust in the determination of death; and raise doubts about fair allocation of organs.

33 of many others currently being used, raises doubts about its effectiveness and benefits (along with

34 strated in human red blood cells (RBCs), but doubts about its functional significance, isoform identi

35 epistasis is ubiquitous, and this has led to doubts about its importance in biological evolution.

36 firm previously reported drivers(6,7), raise doubts about others and identify novel candidates, inclu

37 Opinion article, Brienen et al. (2016) raise doubts about our finding that tropical tree growth has n

38 s of cartilage damage in dogs, raise serious doubts about selective thyroid hormone mimetics as a the

39 haracteristics are not equivalent, and raise doubts about simple models in which intracellular Ca(2+)

40 Recent studies have raised doubts about that view but have uncovered crucial roles

41 Our findings cast further doubts about the ability of ego-depletion manipulations

42 Guala's doubts about the evidential support for this hypothesis

43 emporal lobe structures for memory and raise doubts about the idea that these structures have a promi

44 The ethics of VCA have moved past doubts about the morality of attempting such transplants

45 lations investigated in a recent study raise doubts about the nutritional adequacy of high TFA intake

46 ed exposure of the brain to insulin, raising doubts about the overall physiological relevance of insu

47 2 (VGluT2) mRNA in Ipc neurons, have raised doubts about the purely cholinergic nature of this nucle

48 Recent studies have raised serious doubts about the role of antibiotic prophylaxis after UT

49 ial carcinoma samples were HPV38(+), raising doubts about the significance of the HPV38 association.

50 on-mcr-1-resistant isolates, raising serious doubts about the suitability of these calcium-enhanced m

51 g of currently published case reports raises doubts about the value of many of them but also emphasiz

52 an temperature is not reliable, thus raising doubts about their conclusions.

53 before bleaching was first detected, raising doubts about their possible roles in this process.

54 es of the zeolite structures considered cast doubts about their real-world applicability.

55 nant properties of metamaterials have raised doubts about their usefulness.

56 However, doubts about these assignments have been voiced, fueled

57 -SSIM) also develop severe progeria, raising doubts about whether any treatment targeting protein pre

58 tion-transporting P-type transporters raised doubts about whether P(4)-ATPases alone are sufficient t

59 The purpose of this Perspective is to raise doubts about whether the FFA levels found in real-life s

60 The Lancet Commission has serious doubts about whether the initiatives described in the Pr

61 underpinning scientific disciplines will no doubt accelerate the transfer of polymer therapeutics in

62 In those early days, there was great doubt and skepticism about the utility of UCB as a sourc

63 e LV dysfunction in mitral regurgitation are doubted and poorly followed in clinical practice.

64 loved one, 5) continuity and closure, and 6) doubts and ambivalence.

65 thnic groups was ambivalence about donation: doubts and worries, feeling unsure about donation, wishi

66 write a review of my life as a scientist, I doubted anyone would be interested in reading it.

67 ty for methylated histones in vitro, leaving doubt as to its role in CBX8 chromatin association.

68 ated shark populations, leaving considerable doubt as to their ecological status(1,2).

69 Although subsequent work has raised some doubt as to whether ribotype 027 strains are hypervirule

70 This has raised doubts as to whether developmental processes of the huma

71 Yet their potential is in doubt because of low and slow diffusion, likely because

72 this particular evolutionary hypothesis into doubt by studying emotion perception in a wider sample o

73 articipants with more severe symptoms in the doubt/checking dimension.

74 of activation was inversely associated with doubt/checking symptoms.

75 However, there is doubt concerning the dose, as it seems to be shared, res

76 This study aimed to address these remaining doubts concerning auditory cortical alpha.

77 rdingly, ongoing work in this domain will no doubt continue to deliver exciting progress for improved

78 typing studies; the list of variants will no doubt continue to expand at a rapid rate as genotyping t

79 n these ganglion cell photoreceptors will no doubt continue to illustrate an ever-expanding role for

80 en serum titers and brain pathology have, no doubt, contributed to a delayed appreciation of the cont

81 , the robust inflammatory systematization no doubt contributes to all sickle pathology.

82 ces for the field, including the strategy of doubt creation and the recruitment of epidemiologists by

83 confronted by organized campaigns to spread doubt, denial, and rejection of the scientific community

84 gest disagreement was between benefit-of-the-doubt-derived and principal-component-analysis-derived w

85 characterized by pathological uncertainty or doubt despite compulsive checking with impaired performa

86 ability of the coated blades, which would no doubt enhance consistency in dicing performance and exte

87 There is little doubt evolution has played a major role in preventing th

88 Doubts exist regarding optimal second-line treatment opt

89 Three new studies will no doubt facilitate this transition by generating the C2c1

90 systemic treatment of recurrence are now in doubt following the presentation of the MRC/EORTC CA125

91 After raising some doubts for cultural group selection as an explanation of

92 Without doubt, GFP and spectral derivatives have revolutionized

93 Recently some doubt has arisen concerning the applicability of graphle

94 However, doubt has been drawn on the ubiquity of the mechanism by

95 rstanding of pharmacoresistance, because (1) doubts have been raised about their reproducibility, (2)

96 roscopic donor nephrectomy [LDN]) in adults, doubts have persisted about its use in pediatric recipie

97 The validity of these estimates is in doubt, however, owing to the complex structure of the nu

98 We doubt, however, that those recommendations go far enough

99 Dendritic cells (DCs) are without a doubt important key skin cells that connect information

100 of vaccination was correlated with patients' doubt in the efficacy of the vaccine.

101 to depend upon, a balance between trust and doubt in the stories we share.

102 all 22 cases of Leu/Ile residues, leaving no doubts in identification.

103 a typology of models, and then describe, no doubt inadequately, machine learning and neural networks

104 Such abilities are no doubt key to successful communication in many taxa, but

105 We suspected that those doubts might be premature and hypothesized that the pers

106 Respondents with feelings of guilt doubted more about direct contact.

107 ity that muscle mitochondrial mechanisms, no doubt multifactorial, may be important in deterioration

108 On the other hand, he doubts my assertion that the confinement entropy is alre

109 roduction from innate immune cells, but cast doubt on a different study, which suggests that this miR

110 ranscription factors are infrequent, casting doubt on a direct role for E2Fs in driving cancer.

111 The problems with the data presented cast doubt on all the data, and accordingly also the conclusi

112 These problems with the data presented cast doubt on all the data, and accordingly also the conclusi

113 However, recent evidence has cast doubt on both these associations, tempering hopes of the

114 pressure vary with setting, thereby casting doubt on causality.

115 These results cast doubt on certain experimental methods and demonstrate th

116 efficacy data with drug leads, leaving some doubt on clinical translation.

117 ng abstract shapes, a conclusion which casts doubt on cognitive explanations of fly behaviour in patt

118 This finding casts doubt on earlier assumptions that PI provides directiona

119 difficulties inherent in such controls cast doubt on how effective miRNAs are in driving phenotypic

120 erythromelalgia, supporting recently raised doubt on its causal nature.

121 l amphi-North Atlantic distribution, casting doubt on its non-native status in the NW Atlantic.

122 c cases, and also found in controls, casting doubt on its pathogenicity.

123 onditions, but conflicting results have cast doubt on its role as a photoisomerase.

124 r prostate cancer, further studies have cast doubt on its utility to diagnose this condition.

125 solvent effect on radical stability, casting doubt on key aspects of the captodative effect.

126 The combined results cast doubt on previous reports describing MOF-5 as a semicond

127 by phenyl to naphthyl substitution, casting doubt on previous reports of predicted binding orientati

128 e localisation techniques, therefore casting doubt on reported differences in brain generators.

129 hrenia was not observed, which casts further doubt on schizoaffective diagnosis.

130 e acceleration with age, and would cast some doubt on stage-number inferences from multistage carcino

131 ated with shear thinning and thickening cast doubt on that conclusion and leave unsettled whether the

132 research on spontaneous transformation cast doubt on that interpretation, and motivated re-examinati

133 aps in our knowledge seem to cast additional doubt on the ability of the field to move forward effect

134 o such expansion in the simulations, casting doubt on the accuracy of methods that infer demography f

135 es are of malignant origin, our results cast doubt on the assumption that adherent tumor-derived cult

136 s stable with parental ages and cast further doubt on the assumption that germline mutations track ce

137 Recent studies have cast doubt on the benefit of cardiac resynchronization therap

138 f viral mutagens has been difficult, casting doubt on the clinical viability of this strategy.

139 ized left ventricular ejection fraction cast doubt on the complete reversibility of this condition.

140 hough the incomplete nature of the data cast doubt on the conclusions.

141 ered to be important for those models, casts doubt on the current hypothesised mechanisms of exclusiv

142 In Ghana, a recent report also cast doubt on the current mechanism of delivering free care--

143 Our analysis thus casts doubt on the degree to which quantum discord is necessar

144 ravel advice on malaria prevention, but cast doubt on the effectiveness of current strategies to prev

145 nt to preserve vegetation condition and cast doubt on the effectiveness of protection elevation alone

146 rom priming and aggregate turnover that cast doubt on the existence of SOC with profound intrinsic st

147 r can be retrieved associatively and casting doubt on the general consolidation hypothesis.

148 te short-term glucose homeostasis, but casts doubt on the general usefulness of the inhibition of IDE

149 ells with tumorigenic potential casting some doubt on the hypothesis of hierarchical or differentiati

150 This work casts doubt on the hypothesis that localized tissue modulation

151 distal environmental factors, then they cast doubt on the hypothesis that such factors have large eff

152 These results cast doubt on the hypothesis that the greenish warbler should

153 unohistochemistry hypoxia markers casts some doubt on the hypoxia selectivity of (64)Cu-ATSM.

154 This observation has cast doubt on the importance of disk-driven migration as a me

155 Recent studies in murine models have cast doubt on the importance of JAK2 in CML maintenance.

156 24 h beyond a single exercise bout, casting doubt on the importance of nutrient timing vs. sufficien

157 In addition, our study casts doubt on the importance of protein quantity of PINK1 in

158 o of the three BLUF domains studied, casting doubt on the importance of the formation of a population

159 GS) to the subpolar gyre (SPG) and have cast doubt on the mechanism underlying an apparent pathway fo

160 wide variety of tasks code modality, casting doubt on the notion that these regions embody a central

161 cleosynthesis for realistic conditions casts doubt on the nup process being the explanation for the a

162 e human liver diseases in mice, and has cast doubt on the potential of iPSC-Heps for liver cell thera

163 ble" by current technology, which has casted doubt on the presence of amplifiable botanical DNA.

164 These data cast doubt on the previous supposition that the metabolic rat

165 nd, several arguments have emerged that cast doubt on the relevance of EF effects as a conceptual bas

166 These data cast serious doubt on the relevance of measuring urinary iodide conce

167 larger than previously recognized and casts doubt on the reliability of A(I) estimation by surfactan

168 ation of metazoan lifespan, but they do cast doubt on the robustness of the previously reported effec

169 nding sites for factor VIII (fVIII), casting doubt on the role of exposed PS as the determinant of bi

170 ed or spontaneous vocalizations, which casts doubt on the role of the frontal cortex of the Old World

171 However, recent studies have cast doubt on the role of Vps34 in autophagy, at least in cer

172 Several recent studies, however, have cast doubt on the segregation of touch discrimination and aff

173 Several recent studies, however, cast doubt on the separation of touch discrimination and affe

174 These results cast doubt on the US EPA's recent decision to downscale its e

175 better case-mix adjustment and cast further doubt on the use of utilization-based outcomes as qualit

176 conditions has never been published, casting doubt on the validity of previous calibrations.

177 However, recent evidence has cast doubt on the validity of several putative dependencies t

178 s the source of the catalytic power, casting doubt on the validity of the electrostatic idea, at leas

179 However, recent behavioral studies have cast doubt on the validity of this dichotomy, showing that im

180 d) genistein in certain strains of mice cast doubt on the value of the use of these rodents for gaini

181 l in the Veterans Health Administration cast doubt on the value of using 30-day RSMRs as a means of i

182 These findings may cast doubt on the veracity of those studies that suggest an a

183 sal liverwort lineage Haplomitriopsida casts doubt on the widely held view that Glomeromycota formed

184 bin alpha-immunized heifers, casting further doubt on thecal inhibin alpha subunit having a significa

185 me backgrounds, but recent studies have cast doubt on their ability to substantially increase the rat

186 to rely on priors even when experience sheds doubt on their accuracy.

187 n populations of different ancestry, casting doubt on their biological significance.

188 owever, recent transgenic animal models cast doubt on their direct role in AD pathology.

189 ditions of extremely weak selection, casting doubt on their general relevance.

190 carbon dating of a dozen 'early' grains cast doubt on these claims.

191 We hope to cast some doubt on this assumption and instead argue that the deve

192 ed on a medium-resolution spectrum cast some doubt on this conclusion.

193 evaluation now offered by Pinke et al. casts doubt on this hypothesis.

194 However, recent work casts doubt on this interpretation by showing that mothers wit

195 umerous flaws in the investigation that cast doubt on this message.

196 boxyl tail of an L-type CaV1.3 channel casts doubt on this paradigm.

197 actions reported in the literature have cast doubt on this perception.

198 However, exceptions to Errera's rule cast doubt on whether a broadly applicable rule can be formul

199 nly at z = 3.2, and recent results have cast doubt on whether dust and molecules can be found in typi

200 compared with the other methods, which casts doubt on whether its reconstructions should be favored o

201 zes required to generate these dynamics cast doubt on whether they might be observable in annual plan

202 se nearly normal in its development, casting doubt on xyloglucan's role in wall structure.

203 ortance of NMR spectroscopy studies and cast doubts on drawing conclusions mostly based on single-cry

204 living males from two Bourbon branches cast doubts on its authenticity.

205 recommendations is low, and recent data cast doubts on its validity in the current era.

206 The results cast doubts on recent hypotheses that free thrombin is zymoge

207 These findings raise doubts on the advantages of the currently used ISDC-ther

208 Recent findings, however, cast doubts on the effectiveness of tACS to stimulate the bra

209 These results raised doubts on the formation of ONOO(-) per se at various flu

210 over such large distances casts considerable doubts on the general assumption that risk to ionizing r

211 ents, but lower opal accumulation rates cast doubts on the importance of the EEP as an oceanic region

212 outcome of behavioral experiments, shedding doubts on the inter-laboratory reproducibility of behavi

213 This observation casts doubts on the role of ZipA and its need for cell divisio

214 with multiple sclerosis have caveats casting doubts on their validity.

215 The Italian production is with no doubt one of the most valuable and therefore mostly coun

216 d and legitimize their symptoms, remove self-doubt or blame, and identify factors that contribute to

217 for temporal lobe epilepsy and thus casting doubt over the conclusions drawn from semantic dementia

218 ck of activating pathway mutations have cast doubt over the significance of these observations.

219 These unexpected findings cast doubt over the utility of phosphoinositide 3-kinase inhi

220 risk within the SZ genotype, raising further doubts over the need for intravenous AAT augmentation in

221 ment of detection, there have been lingering doubts over the technique's quantitative reliability and

222 f allostasis was proposed some 30 years ago, doubts persist about its precise meaning and whether it

223 The existence of such neurons has been doubted recently as a result of the observation that itc

224 cialized centres and where there is room for doubt, referral to such a centre is probably wise.

225 the further addition of (unlabeled) RRM2, no doubt reflecting competition for binding to the i-motif

226 assumptions regarding causality have created doubt regarding some conclusions.

227 nfection has been uncertain, contributing to doubt regarding the utility of experimental challenge mo

228 ess, guilt over the decisions they made, and doubt regarding whether they had made the right decision

229 ion in a cost-effective manner but there are doubts regarding data reliability.

230 This, in conjunction with recently raised doubts regarding some of the Mg(2+) assignments near the

231 There have, however, long been doubts regarding the monophyletic origin of planktic for

232 ability has been thoroughly documented, some doubts remain about the precise photophysical mechanism

233 Doubts remain about the risk of temporary DAT discontinu

234 conjugation has been published to date, and doubts remain about whether such cysteine-targeting inhi

235 tional modulations of visual alpha activity, doubts remain as to the existence and functional relevan

236 Although basically no doubts remain that CXCR4 represents a classic chemokine

237 -1 genes and periodontitis, but considerable doubt remains about the patient populations in which the

238 These responses no doubt represent only a small sample of the chemomechanic

239 o change substantially, in ways that will no doubt see substance use playing an increasingly large pa

240 mediacy of Ni(0)-ate complexes, leaving some doubt that a canonical catalytic cycle consisting of an

241 There is no doubt that a simple isoquinoline alkaloid, tetrahydropap

242 It is no doubt that accurate high-throughput phenotyping will acc

243 However, although there is no doubt that activated monocytes trigger coagulation in a

244 There is no doubt that an improved influenza vaccine is on the horiz

245 While there is no doubt that biogenic methane production in the Arctic is

246 There is little doubt that calcium-containing crystals are involved in t

247 its vary widely, and there may be reasons to doubt that claims of efficacy reflect real-world effecti

248 ormulation, we demonstrate beyond reasonable doubt that entropy predominates the thermodynamic landsc

249 There can be little doubt that genetics has transformed our understanding of

250 turized electrodes with enzymes, there is no doubt that most of the available deposition processes su

251 ugh the available body of evidence leaves no doubt that neutrophils are integral to periodontal tissu

252 ular studies, enabled us to establish beyond doubt that Nothomicrodon belongs to the Phoridae (Insect

253 There is little doubt that predictive coding is an important mechanism i

254 While there is no doubt that prevention is desirable, the evidence of the

255 Although there is no doubt that prokaryotic and organellar group II introns a

256 al performance as protease inhibitors raises doubt that propeptide stability alone is sufficient for

257 There is no doubt that renal replacement therapy for the most severe

258 While there is no doubt that social signals affect human reinforcement lea

259 There is no doubt that the contribution of microbially mediated biop

260 k's group has demonstrated beyond reasonable doubt that the dimeric LPd(I) Br catalysts that are wide

261 r other mobile genetic elements, there is no doubt that the LUCA was a host to viruses.

262 Although there is little doubt that the maturation of specific inhibitory circuit

263 There is no real reason to doubt that the peculiarities of the formation of DB anio

264 Although there is no doubt that the presence of multiple species during the m

265 In this study, we demonstrate beyond doubt that the slicer activity of Piwi is not required f

266 Although there is no doubt that the use of common systematic approaches for m

267 panding transmission of HCV, there is little doubt that there is a need for implementing what is in t

268 udimentary, the available evidence leaves no doubt that these small post-transcriptional regulators a

269 There is no doubt that this technology opens up a world of possibili

270 hough yet to be clearly defined, there is no doubt that transcatheter mitral valve procedures will ha

271 -level deworming; however, it remains beyond doubt that treatment reduces the severe consequences of

272 acteristic of psychosis lies in a persistent doubt that undermines the stabilization of behavioral po

273 There is little doubt that with the development of more efficient and fa

274 I had no doubt that working with kDNA would be a challenge, as I

275 Skeptics doubted that many CLs would occur, given political press

276 ospitals poor grades on patient safety, many doubted that safety was a management priority.

277 This has led to doubts that Mars can be described adequately using the '

278 The liver is beyond any doubt the most important metabolic organ of the human bo

279 These findings call into doubt the proposed proprioceptive function of palisade e

280 nal control of cholesterol synthesis, and no doubt the road ahead will reveal further twists and turn

281 in how both are the subject of campaigns to doubt the science.

282 appropriate control group; this brings into doubt the study's conclusions.

283 ken translational symmetry in two dimensions-doubting the existence of 2D crystals-and the first comp

284 Without a doubt, the 1985 publication by Willett et al. provided t

285 gnosis of myocardial infarction (MI), beyond doubt, the most important indication of hs-cTn assays, t

286 In fact, we doubt there are two systems.

287 Without doubt, there is an urgent need for new effective anticlo

288 this hydrolysis step were unknown and widely doubted to exist.

289 inconvenience), ambivalence and uncertainty (doubting transplant urgency, insufficient information, c

290 to ultraviolet radiation exposure is beyond doubt, ultraviolet-radiation-independent events are like

291 Our results cast doubt upon one of the last widely discussed pieces of ev

292 These data cast doubt upon the existence of a chloroplast movement-depen

293 Endotyping is without doubt useful to predict the natural course of disease, t

294 This doubt was exacerbated in a few cases as families were un

295 There is no doubt whatsoever which environmental factors, probably d

296 Hence, we doubt whether Big Gods and prosocial religions are more

297 ults from recent Mars missions, calling into doubt whether the igneous histor y inferred from the met

298 the development of hypospadias, but there is doubt whether the incidence of hypospadias is increasing

299 Unfortunately, this finding raises doubts whether beta-bursts can be a causal mechanism of

300 impaired by limited sampling, and we have no doubt witnessed but a small subset of their diversity.