ライフサイエンスコーパス: dramatic change

1 d DKD glomeruli, and PLK2 exhibited the most dramatic change.

2 otein filaments, with G151D showing the most dramatic changes.

3 pe B aortic dissection (ATBAD) is undergoing dramatic changes.

4 ic health provision in England is undergoing dramatic changes.

5 contrast of gray and white matter undergoes dramatic changes.

6 The most dramatic changes (1711 transcripts up- and 3242 down-reg

7 Extracellular matrix undergoes dramatic changes after MI and therefore might be linked

8 cortex matures late in development, showing dramatic changes after puberty onset, yet few experiment

9 ve integrative computational methods reveals dramatic changes along a remarkably stable developmental

10 Dramatic changes also were seen in the chromatin, with a

11 As the global population urbanizes, dramatic changes are expected in city lighting and the u

12 es, intron length and PATC-character undergo dramatic changes as orthologs move from active to repres

13 Our food system is experiencing dramatic changes as the expansion of e-commerce, introdu

14 alysis of motor cortical activity revealed a dramatic change between behaviors in the coordination of

15 n a ferromagnet, its spin moment undergoes a dramatic change, but how it works remains a mystery.

16 stromal extracellular matrix (ECM) undergoes dramatic changes during development and in tumorigenesis

17 rotubule organization, both of which undergo dramatic changes during erythroblast enucleation.

18 in and nuclear pore complexes (NPCs) undergo dramatic changes during mitosis, which in vertebrates an

19 al domains of epithelial cells often undergo dramatic changes during morphogenesis to form specialize

20 gulation of myosin isoforms did not show any dramatic changes during the observation period.

21 Dramatic changes have occurred in the Arctic Ocean over

22 eps to deeply understand the drivers of such dramatic changes: (i) describe fundamental demographic r

23 h of the replication initiation sites, but a dramatic change in (CTG)(n) .

24 Surprisingly, there was no dramatic change in activity profile with respect to age

25 The molecular basis of this dramatic change in behavior upon introduction of the V(6

26 This was associated with a dramatic change in cell morphology from one with scant c

27 erular disease, podocyte injury results in a dramatic change in cell morphology known as foot process

28 ding pathogens or cellular debris requires a dramatic change in cell shape driven by actin polymeriza

29 ultures to the dark, which correlated with a dramatic change in cell surface morphology, likely refle

30 ellular matrix of CP cells, which leads to a dramatic change in cellular morphology.

31 The dramatic change in color of these compounds from red (3,

32 congenital heart defect has undergone a more dramatic change in diagnostic approach, management, and

33 ia, we show that the virus has experienced a dramatic change in evolutionary behavior over the last 2

34 0 My after the extinction, and resulted in a dramatic change in faunal composition.

35 (all P > .01) representation, suggesting no dramatic change in future representation as practicing p

36 and this replication process brings about a dramatic change in optical properties of the sample-a ch

37 These approaches overlook the dramatic change in our understanding of life's diversity

38 e humoral immune response, B cells undergo a dramatic change in phenotype to enable antibody affinity

39 s (271.15 K and 272.15 K), as shown from the dramatic change in Raman spectra and fluctuations in AL/

40 nge in body shape was preceded by an equally dramatic change in sensory abilities akin to transitioni

41 ntrol of interfacial interactions leads to a dramatic change in shape and morphology for particles ba

42 The most dramatic change in specificity resulted from substitutio

43 To address the effect of dramatic change in temperature and viscosity during PCR

44 ned upon deletion of the 7-propionate, but a dramatic change in the 7-propionate carboxylate (13)C ch

45 The dramatic change in the activity of RA neurons during the

46 Thus, ICOS strongly contributed to the dramatic change in the balance between Ag-specific Teff

47 Several recent studies have shown a dramatic change in the behavior of flagellated bacteria

48 distortion of the protein blue Cu site and a dramatic change in the charge transport regime of the si

49 Exercise stimulates a dramatic change in the concentration of circulating horm

50 This leads to a dramatic change in the extent of activated cullin-RING u

51 There is, however, a dramatic change in the form of the gap anisotropy with r

52 The dramatic change in the geographic patterns of heart dise

53 Such a dramatic change in the global epidemiology of ASF has re

54 The transition is driven by a dramatic change in the interactions among Ir 5d orbitals

55 This dramatic change in the interfacial tension enables a var

56 ancer therapeutics has undergone a rapid and dramatic change in the last few years.

57 Cs in vivo after chemotherapy, identifying a dramatic change in the physiology of primitive AML cells

58 der a bifunctional organocatalyst provokes a dramatic change in the regioselectivity, from the 1,5- t

59 Surprisingly, binding of S8 leads to a dramatic change in the RNA conformation that restores th

60 Single-crystal X-ray diffraction reveals a dramatic change in the solid-state arrangement with exch

61 erse spin Hall effect measurement, we find a dramatic change in the spin pumping signal (decrease by

62 alkyl-functionalized surfaces that reveal a dramatic change in the surfaces' hydrophobic interaction

63 structure of a small molecule can lead to a dramatic change in the target profile of the molecule ev

64 and has stimulated optimism for achieving a dramatic change in the trajectory of the HIV epidemic.

65 In the past decade, we have witnessed a dramatic change in the treatment paradigms due to the de

66 de/resolvation behavior is accompanied by a dramatic change in their magnetic properties: The dihydr

67 cells phagocytosed by macrophages undergo a dramatic change in their metabolism in which amino acids

68 e nucleotide-binding domains that involves a dramatic change in their relative orientation.

69 , and recruited dendritic cells all showed a dramatic change in their resolution signature following

70 m levels, FCVA-deposited carbon films show a dramatic change in their structure in terms of loss of s

71 opically expressing 90 CGG repeats exhibit a dramatic change in their translational profile even prio

72 zes with loss of APC activity resulting in a dramatic change in tumor multiplicity, size, morphology

73 The spliceosome undergoes dramatic changes in a splicing cycle.

74 Here we investigate the widespread and dramatic changes in adult migration characteristics of w

75 ns falling within the Abeta sequence lead to dramatic changes in aggregation kinetics and influence t

76 icate that certain prion strains can undergo dramatic changes in biological properties that are not d

77 Among the most dramatic changes in both sexes were a decrease in concen

78 Motherhood is characterized by dramatic changes in brain and behavior, but less is know

79 Dramatic changes in cell and nuclear size occur during d

80 These dramatic changes in cell morphology depend on the auto-p

81 asma capsulatum, are soil fungi that undergo dramatic changes in cell shape and virulence gene expres

82 tion to the actin cytoskeleton, resulting in dramatic changes in cell shape, notably the formation of

83 toward different phenotypes in vitro exhibit dramatic changes in cell shape: M2 cells exhibit an elon

84 of complex structures after injury requires dramatic changes in cellular behavior.

85 virus nonstructural protein 4 (NSP4) induces dramatic changes in cellular calcium homeostasis.

86 ntial is beneficial to overall organ health, dramatic changes in cellular identity can have disastrou

87 ependent activation of naive T cells induces dramatic changes in cellular metabolism that are essenti

88 ble, and T-cell activation is accompanied by dramatic changes in cellular metabolism.

89 ct alterations in mitochondrial networks and dramatic changes in cellular morphology related to cofil

90 Pollen grains undergo dramatic changes in cellular water potential as they del

91 The mutations p.A749G and p.G407R caused dramatic changes in channel gating by shifting (~15 mV)

92 sity in glucose-rich conditions, and undergo dramatic changes in chromatin status after glucose deple

93 Cellular senescence is accompanied by dramatic changes in chromatin structure and gene express

94 Dramatic changes in chromatin structure and histone modi

95 ry and follicular helper T (T(FH)) cells and dramatic changes in cytokine production in both patients

96 Dramatic changes in dietary fat intake (-61%; P<0.001 ve

97 These studies revealed dramatic changes in diffusion coefficient and the degree

98 h transmission electron microscopy to reveal dramatic changes in dislocation structure and sub struct

99 that incorporates a reversible reaction, and dramatic changes in dynamics with small modifications in

100 nt ecological dominance often coincided with dramatic changes in Earth's atmospheric composition.

101 y of life, development is rapid and includes dramatic changes in eating behavior.

102 We show that dramatic changes in electrochemical stiffness occur due

103 balance between competing phases, leading to dramatic changes in electronic and magnetic properties.

104 Dramatic changes in exposure of a repressive chromatin m

105 brain undergoes protracted development, with dramatic changes in expression and regulation of emotion

106 uring interaction with endobacteria revealed dramatic changes in expression of lipid metabolic genes

107 that in FL, spatial organization results in dramatic changes in FL biology, including gene expressio

108 ons to the indole-2-carboxamide motif confer dramatic changes in functional affinity (5000-fold incre

109 rations of a material oftentimes bring about dramatic changes in functional properties as a result of

110 ase spirochete Borrelia burgdorferi exhibits dramatic changes in gene expression as it transits betwe

111 tching, extensive epidermal hyperplasia, and dramatic changes in gene expression in sensory neurons a

112 The dramatic changes in gene expression required for develop

113 Cellular transitions require dramatic changes in gene expression that are supported b

114 y response in human cells involves rapid and dramatic changes in gene expression, and the Bru-Seq and

115 Cellular transformation is associated with dramatic changes in gene expression, but it is difficult

116 hich induces genetic instability, results in dramatic changes in gene expression, resembling changes

117 Axon injury triggers dramatic changes in gene expression.

118 itate chromosome segregation, accompanied by dramatic changes in gene expression.

119 ith ectopic overexpression of miR-203 showed dramatic changes in gene networks related to cell cycle

120 Since most dramatic changes in genomic architectures are caused by

121 n cells triggers major imbalances in NSs and dramatic changes in glycolipids and glycoproteins, inclu

122 . aureus, but not S. aureus Deltapsm, we saw dramatic changes in gross pathology, as well as systemic

123 bits an unstable environment and must endure dramatic changes in habitat chemistry.

124 Bone marrow neuropathy results in dramatic changes in hematopoiesis that lead to microvasc

125 ds, favors its own transmission by producing dramatic changes in host reproduction.

126 ughout infection, pathogenic bacteria induce dramatic changes in host transcriptional repertoires.

127 Despite dramatic changes in IMTG content on both chow and high-f

128 expression using Cre/LoxP technology caused dramatic changes in in gastric motor activity, with disr

129 These transitions include dramatic changes in intestinal contents and require appr

130 ion at the centrosome that is accompanied by dramatic changes in its phosphorylation state.

131 Every day and night, the retina undergoes dramatic changes in its physiology and function.

132 All three FSS mutations show dramatic changes in kinetic properties, most notably the

133 1 AND 2) transcription factors, resulting in dramatic changes in leaf morphogenesis and increased sus

134 orter inflorescences with fewer flowers, and dramatic changes in leaf shape and complexity.

135 Given the dramatic changes in lifestyles and disease patterns that

136 ular chaperone, which couples ATP binding to dramatic changes in local structure required for protein

137 M1-to-M2 shift in macrophage composition and dramatic changes in macrophage gene expression in both M

138 d enthalpies of different conformers undergo dramatic changes in magnitude and relative order to main

139 ibitors of recombinant LSD1 but that produce dramatic changes in methylation at the histone 3 lysine

140 The most dramatic changes in microbial taxonomic abundance occurr

141 Priority effects also manifest as dramatic changes in microbiome development dynamics betw

142 These events include dramatic changes in mitochondrial genome content and org

143 -related loss of tissue homeostasis, despite dramatic changes in mitochondrial ultrastructure and mit

144 Dramatic changes in molecular structure, degradation pat

145 or example, and red blood cells also undergo dramatic changes in morphology and receptor density as t

146 hen all virions are in the postfusion state, dramatic changes in morphology are apparent: elongated p

147 Differentiating erythroid cells undergo dramatic changes in morphology, with reduction in cell s

148 ish in which fathers provide care-experience dramatic changes in neurogenomic state as they become fa

149 s of chromatin are believed to contribute to dramatic changes in neuronal circuitry.

150 uggest a mechanistic basis for achieving the dramatic changes in organelle positioning seen during ce

151 Because of dramatic changes in our understanding of human genetic v

152 Especially dramatic changes in overt rhythms and morphology occur d

153 tion to control malaria results in rapid and dramatic changes in parasite population genomics.

154 cond- or subsequent line therapy resulted in dramatic changes in patterns of failure, was well tolera

155 Sudden and dramatic changes in perception occur when prior knowledg

156 Studies in altricial rodents attribute dramatic changes in perinatal cardiomyocyte growth, matu

157 esponse to low oxygen in HeLa cells leads to dramatic changes in plasma membrane structure.

158 n of endovascular techniques has resulted in dramatic changes in practice patterns and has refocused

159 Cumulatively, results indicate dramatic changes in prognoses for adult kidney transplan

160 ranscriptomic assessment of these EVs showed dramatic changes in protein and miRNA content long after

161 We observed significant and dramatic changes in ringed seal stable isotope values be

162 vesicles in endocytic compartments leads to dramatic changes in scattering properties and SERS signa

163 in cellular tropoelastin protein levels and dramatic changes in secreted tropoelastin physical struc

164 Our results show that dramatic changes in selectivity can be obtained through

165 ubiquitin to a target protein, revealing the dramatic changes in shape that enable it to modify parti

166 Both zeatin and BR induce dramatic changes in signaling and metabolism.

167 We observed dramatic changes in single unit activity during learning

168 These trends may be associated with the dramatic changes in smoking behavior that took place in

169 the observed bidirectional scaling, whereas dramatic changes in spiking activity associated with spo

170 Here, we find that dramatic changes in spiking activity in the embryonic sp

171 lyldimethylammonium chloride) (PDADMAC) show dramatic changes in ST when the concentration of SDS var

172 Our results highlight dramatic changes in structure and function along the len

173 he GB and that these boundaries undergo less dramatic changes in structure upon irradiation.

174 difications in the crystal structure lead to dramatic changes in symmetry and selection rules of vibr

175 ng interactions, etc., that are reflected by dramatic changes in temperature-dependent chemical shiel

176 pped in the caves, they were confronted with dramatic changes in the availability and type of food so

177 is a top concern for social well-being, and dramatic changes in the availability of freshwater have

178 yer behavior of ceramides, some causing more dramatic changes in the bilayer properties, whereas othe

179 , are associated with cardiomyocyte loss and dramatic changes in the cardiac extracellular matrix (EC

180 carcinoma cell-line HCT116 p53(++), causing dramatic changes in the cell cycle without DNA damage.

181 Dramatic changes in the cellular microenvironment are al

182 ate millions of erythrocytes daily, involves dramatic changes in the chromatin structure and transcri

183 Mice deficient in clock exhibited dramatic changes in the circadian rhythm of renal sodium

184 The miRNA-mRNA interactome showed dramatic changes in the Clk(jrk) flies.

185 and show that familial mutations can induce dramatic changes in the crucial processes thought to be

186 species-centric approach neglects the often dramatic changes in the ecology of organisms during thei

187 in most organic electronics devices and that dramatic changes in the electronic properties can be ind

188 On Earth, all life is exposed to dramatic changes in the environment over the course of t

189 The dramatic changes in the epidemiology of Clostridium diff

190 Dramatic changes in the epidemiology of Culicoides-borne

191 f and Belding Scribner set in motion several dramatic changes in the epidemiology, economics and ethi

192 Our data indicate dramatic changes in the epigenome due to diet and demons

193 Nonetheless, dramatic changes in the experimental spectra are observe

194 he actin-remodelling protein cofilin induces dramatic changes in the F-actin network and consequent c

195 at valence fluctuations of YbAl3 can lead to dramatic changes in the Fermi surface topology in recipr

196 e show that valence fluctuations can lead to dramatic changes in the Fermi surface topology, even res

197 Early loss of vision produces dramatic changes in the functional organization and conn

198 Moreover, the dramatic changes in the functional properties of PU02 in

199 E. chaffeensis infection did not result in dramatic changes in the global host SUMOylated protein p

200 alter the responses of NKT cells, leading to dramatic changes in the global immune response.

201 While IBD has been associated with dramatic changes in the gut microbiota, changes in the g

202 ee electricity will almost certainly require dramatic changes in the infrastructure and topology of t

203 the wild-type level of activity, and showed dramatic changes in the light/dark cycle of CAM CO(2) fi

204 Exposure of KCs to PV sera also caused dramatic changes in the mitochondrial membrane potential

205 We found that E4orf4 induced dramatic changes in the morphology of mitochondria along

206 in molecular phylogeny are about to lead to dramatic changes in the naming of medically important mo

207 Dramatic changes in the North American landscape over th

208 Dramatic changes in the NRVS are seen under high-CO cond

209 Nonetheless, BMSC treatment produced dramatic changes in the number and activation of brain a

210 ommon and more intense forest fires, causing dramatic changes in the nutrient storage and loss from f

211 The attachment of functional groups leads to dramatic changes in the optoelectronic properties of the

212 of host innate immune responses may lead to dramatic changes in the outcome of infection.

213 Small-bowel radiology has undergone dramatic changes in the past 2 decades.

214 Adult pair bonding involves dramatic changes in the perception and valuation of anot

215 Energetic radiation can cause dramatic changes in the physical and chemical properties

216 es in the hP2X2 middle vestibule resulted in dramatic changes in the potency of zinc inhibition.

217 These studies implicate dramatic changes in the reaction mechanisms and suggest

218 tation (CLIP) sequencing, we uncover several dramatic changes in the RNA-binding properties of Gag th

219 ked strands (e.g., 5'3' vs 3'3') can lead to dramatic changes in the self-assembly behavior, from the

220 day 0 (P0) to hearing onset (P12), undergoes dramatic changes in the sensitivity to acetylcholine (AC

221 We discovered dramatic changes in the sequence variation and abundance

222 f interactions among neurons can manifest as dramatic changes in the state of population dynamics in

223 analysis revealed that an oprD mutant showed dramatic changes in the transcription of genes that may

224 One of the most dramatic changes in the transcription program in Drosoph

225 ins and well below the doping level at which dramatic changes in the transport properties are reporte

226 in the axial coordinating linkers result in dramatic changes in the transport properties of the meta

227 in the North Pacific Subtropical Gyre reveal dramatic changes in the upper 500 m of the water column

228 AFS spectra of Zn model compounds, indicates dramatic changes in the Zn speciation from upstream to d

229 Why metalloenzymes often show dramatic changes in their catalytic activity when subjec

230 can adapt to a broad spectrum of sudden and dramatic changes in their environment.

231 d Leiocephalus carinatus was associated with dramatic changes in their foraging niche.

232 During development, cells undergo dramatic changes in their morphology.

233 Golgi in irx9 also displayed dramatic changes in their structure, with increases in c

234 Alphaviruses, such as Sindbis virus, undergo dramatic changes in three-dimensional structure upon exp

235 The dramatic changes in TNTBN provide evidence that the tran

236 Remarkably, despite dramatic changes in tRNA isodecoder gene expression, the

237 rm line and Bmp10 in the right atrium led to dramatic changes in vascular tone and diminution of the

238 se biomass-burning episode, synchronous with dramatic changes in vegetation, including a high-disturb

239 The dramatic changes in viral load and CD4 cell count after

240 such as cornstarch mixed with water) exhibit dramatic changes in viscosity when sheared, producing fa

241 essing the touristic impacts and address the dramatic changes in visitor population and drug consumpt

242 Calcium stress induces dramatic changes in VSMC exosome composition and accumul

243 cosystems, hurricanes and flooding can cause dramatic changes in water quality resulting in large mor

244 so been associated with similar, albeit less dramatic, changes in methylation patterns, leading to th

245 Thus, we demonstrate that the dramatic changes incurred by Dehnel's phenomenon occur i

246 The reason for this dramatic change is not apparent, but we propose that it

247 In this work, the origin of these dramatic changes is correlated for the first time with s

248 d that the Ae. tauschii region has undergone dramatic changes; it has acquired more than 80 non-synte

249 The most dramatic change occurred in the Neoaves after the Cretac

250 different behavior, which we attributed to a dramatic change of the amyloid structure.

251 Loss of trol causes a dramatic change of the ECM into a three-dimensional, spo

252 We found a dramatic change of the overall tertiary structure of pro

253 upon hybridization with hgDNA584 leads to a dramatic change of the pillar scale due to hgDNA584 fill

254 d, the combination of CuO with HFUS led to a dramatic change of the reaction selectivity, with glucur

255 phenomenon, the lattice may be coupled with dramatic changes of orbital and/or the spin-state of the

256 -type to an ordered-ilmenite structure, and dramatic changes of the electrical and magnetic properti

257 ferroelastic domain walls in SrTiO3 leads to dramatic changes of the magnetic domain structure of a n

258 he brain and the immune system has undergone dramatic changes over the last two decades, with immense

259 The Earth's climate has experienced dramatic changes over the past 22,000 years; however, th

260 nic lymphocytic leukemia (CLL) has undergone dramatic changes over the previous 2 decades with the in

261 Our study reveals dramatic changes over time, with a reduction in total nu

262 This quite dramatic change possibly occurs as a result of competiti

263 tment of acute ischemic stroke has undergone dramatic changes recently subsequent to the demonstrated

264 that strong electron-phonon coupling and its dramatic change should be incorporated into or reconcile

265 iod of early adolescence is characterized by dramatic changes, simultaneously affecting physiological

266 The field of hepatology has experienced dramatic changes since the last workforce study in hepat

267 ract is immature at birth, yet must adapt to dramatic changes such as oral nutrition and microbial co

268 sequence changes at promoters, we show that dramatic changes such as the complete gain and loss (col

269 s with redox-active drugs resulted in a more dramatic change than hypoxia alone.

270 One dramatic change that occurs is the closure of the ductus

271 punctuation: it consists of abrupt bursts of dramatic change that separate long periods of largely un

272 why we believe that we are on the cusp of a dramatic change that will sweep a wave of automation int

273 Polyploidization is one of the most dramatic changes that can occur in the genome.

274 lizations in infant marmoset monkeys undergo dramatic changes that cannot be solely attributed to sim

275 They were shaped by the dramatic changes that occurred in the evolution of the p

276 Such a dramatic change to an asthenospheric contribution appear

277 modern cosmopolitan lifestyle resulted in a dramatic change to the human gut microbiome.

278 erahertz microscopy, we find that there is a dramatic change to the vibrational directionality with i

279 These results demonstrate that dramatic changes to actin architecture can be made simpl

280 nerozoic despite similar, and sometimes more dramatic changes to carbon sinks.

281 G0 entry involves dramatic changes to chromatin and transcription of cells

282 The differentiation of gametes involves dramatic changes to chromatin, affecting transcription,

283 s is a differentiation process that requires dramatic changes to DNA architecture, a process governed

284 Dramatic changes to NPIP gene structure and altered tiss

285 We find that dramatic changes to the bulk solvent cause only weak cha

286 uence on development starts to decrease, and dramatic changes to the cell cycle take place.

287 Time delays may cause dramatic changes to the dynamics of interacting oscillat

288 immature and mature HAstV particles revealed dramatic changes to the exposure of conserved residues d

289 parasite, Plasmodium falciparum, results in dramatic changes to the host cell structure and morpholo

290 Our results demonstrate dramatic changes to transcription and chromatin structur

291 based artificial honeycomb lattice undergoes dramatic changes upon application of magnetic fields and

292 son whose number and activity do not undergo dramatic changes upon inbreeding or outcrossing.

293 ally silenced during retinogenesis, the most dramatic change was derepression of cell-type-specific d

294 Among the most dramatic changes, we observed rapid and sustained phosph

295 The most dramatic changes were caused by variants that produced A

296 y 3, Day 11 and Day 27 was evident, and more dramatic changes were found between baseline and other t

297 e funding in the United States is undergoing dramatic change which will require a new set of assumpti

298 HSCs undergo dramatic changes with aging.

299 here over the past two decades has witnessed dramatic changes, with continuous improvement in develop

300 There have been dramatic changes worldwide in the attitudes toward and c