ライフサイエンスコーパス: duct cell

1 l target genes in inner medullary collecting duct cells.

2 compartment differentiate into endocrine and duct cells.

3 ion and continue to generate both acinar and duct cells.

4 ctivity in aldosterone-stimulated collecting duct cells.

5 ldosterone-stimulated mpkCCD(c14) collecting duct cells.

6 ion of surviving mature hepatocytes and bile duct cells.

7 the apical membranes of mouse salivary gland duct cells.

8 ion on EP4 receptors expressed on collecting duct cells.

9 ession of Ascl3 is restricted to a subset of duct cells.

10 shed in P2X(7)(-/-) submandibular acinar and duct cells.

11 rin-2 (AQP2) trafficking in renal collecting duct cells.

12 ngII) type 1 receptor (AT(1)R) in collecting duct cells.

13 cells with similarities to mature pancreatic duct cells.

14 presence of RyR2 in the medullary collecting duct cells.

15 ERK and P38 in the cultured mouse collecting duct cells.

16 O(2) on c-Src expression in mouse collecting duct cells.

17 ize in the nuclei of mIMCD3 renal collecting duct cells.

18 human kidneys (NHK) and M-1 mouse collecting duct cells.

19 choline, whereas secretin receptors regulate duct cells.

20 n kinase and increased proliferation of bile duct cells.

21 elial Na(+) transport in cortical collecting duct cells.

22 al player to generate endocrine, acinar, and duct cells.

23 rane exosomes from mouse cortical collecting duct cells.

24 e adult is present only in some intercalated duct cells.

25 ivated protein kinase, and Src in pancreatic duct cells.

26 eton had no effect on P2X7R gating by ATP in duct cells.

27 and 18 in CFTR expression in some pancreatic duct cells.

28 PKbeta pathway in inner medullary collecting duct cells.

29 s functionally expressed in mouse pancreatic duct cells.

30 NHE3 was restricted to the apical region of duct cells.

31 e studied pNBC1 function in mouse pancreatic duct cells.

32 ductance in renal inner medullary collecting duct cells.

33 sufficient to confer activity in collecting duct cells.

34 r in cultured rat inner medullary collecting duct cells.

35 ells, whereas expression was not detected in duct cells.

36 n transport in M-1 mouse cortical collecting duct cells.

37 as located apically, toward the lumen in the duct cells.

38 on of epithelial cells as well as pancreatic duct cells.

39 ve target cells, i.e. in cortical collecting duct cells.

40 Na(+) transport in mouse cortical collecting duct cells.

41 ent ERK phosphorylation in benign pancreatic duct cells.

42 capable to differentiate into SG acinar and duct cells.

43 s of exosomes from mouse cortical collecting duct cells.

44 to generate hepatocytes and duct cells, only duct cells.

45 n autoimmune insult on the kidney collecting duct cells.

46 quaporin-2 water channel in renal collecting duct cells.

47 alpha-ENaC expression in cortical collecting duct cells.

48 ith autoantibodies against kidney collecting duct cells.

49 rier formation in Grhl2-deficient collecting duct cells.

50 ecular markers separated presumptive bud and duct cells.

51 amics in polarized mouse cortical collecting duct cells.

52 esmopressin stimulation of kidney collecting duct cells.

53 ater and Na(+) transport in renal collecting duct cells.

54 trastructural features of both endocrine and duct cells.

55 thelial and mouse inner medullary collecting duct cells-3.

56 cellent approach for studying lacrimal gland duct cells about which relatively little is known at the

57 hypertonicity in inner-medullary collecting duct cells adapted to survive in hypertonic conditions.

58 gans excretory (renal) system, the excretory duct cell and pore cell.

59 regulation of COX-2 expression in collecting duct cells and (ii) to assess the possible contribution

60 is induced by high-salt levels in collecting duct cells and activates the Slc14a2 gene by recruiting

61 reatic cell types including endocrine cells, duct cells and endothelial cells.

62 and their subsequent differentiation to bile duct cells and hepatocytes.

63 scence to consist of cytokeratin 19-positive duct cells and hormone-positive islet cells.

64 ching morphogenesis using primary pancreatic duct cells and identified a transient surge of Pdx1 expr

65 ndogenous ENaCs in mouse cortical-collecting duct cells and in primary cultures of human airway epith

66 transport had no effect on [Cl-]i changes in duct cells and inhibited only about 50% of Cl- uptake in

67 proximal cells are bipotent and give rise to duct cells and late-born endocrine cells, including the

68 uctures containing both parenchymal and bile duct cells and liver repopulation was extensive (60 to 8

69 acini, which undergo rapid reprogramming to duct cells and longer-term reprogramming to endocrine ce

70 polarized cultures of mouse renal collecting duct cells and mice treated with clinically relevant lit

71 ultured rat renal inner medullary collecting-duct cells and microarray analysis to identify genes aff

72 ongated in proximal tubule cells, collecting duct cells and parietal cells of the remaining kidney.

73 l protein expression is detected in salivary duct cells and peripheral nerve ganglia.

74 y treating immortalized mouse M-1 collecting duct cells and primary cultures of human kidney epitheli

75 re we provide evidence from renal collecting duct cells and serum- and glucocorticoid-induced kinase-

76 s process, we observed proliferation of bile duct cells and small epithelial cells, although transpla

77 arbonate and fluid secretion from pancreatic duct cells and suggested that cholecystokinin stimulatio

78 mulated COX-2 expression in mouse collecting duct cells and that 2) COX-2 may play a role in cell sur

79 te a progenitor-progeny relationship between duct cells and the acinar cell compartment, and identify

80 nction of receptors on pancreatic acinar and duct cells and the multiple intracellular signaling path

81 in the submandibular gland (SMG) acinar and duct cells and their regulation by basolateral and lumin

82 ) mouse to lineage-trace Hnf1beta(+) biliary duct cells and to assess their contribution to LPC expan

83 ries of studies suggest that neogenesis from duct cells and transdifferentiation of alpha-cells are p

84 the bestrophins are expressed in pancreatic duct cells and, more specifically, that hBest1 plays a r

85 n excretory cell, an excretory gland cell, a duct cell, and a pore cell.

86 ficiently taken up by striated and excretory duct cells, and eventually secreted into saliva.

87 ific immunolocalization of sAC in collecting duct cells, and immunoblots confirmed sAC expression in

88 f neonatal mice has a unique tropism to bile duct cells, and it triggers a hepatobiliary inflammation

89 he presence of human endothelial and biliary duct cells, and secreted human albumin that was detected

90 pression in mouse inner medullary collecting duct cells, and this effect was abrogated by AT(1)R bloc

91 ound to be restricted to a subset of biliary duct cells antigenically defined as CD45(-)/CD11b(-)/CD3

92 These results suggest that in parotid duct cells apical NHE2 and NHE3 do not play a major role

93 To test whether pancreatic duct cells are in vitro progenitors, they were purified

94 Adam10 in determining the fate of collecting duct cells are more complex than those of a simple upstr

95 HNF1beta(+) biliary duct cells are the origin of LPC.

96 n the pancreas, and reveals adult pancreatic duct cells as a latent multipotent cell type.

97 um stress as an early step and the status of duct cells as important entities in pancreatic injury.

98 ancreatic duct cells, challenges the role of duct cells as progenitors, and suggests a genetic mechan

99 murine pancreatic centroacinar and terminal duct cells, as visualized using fluorescent microscopy.

100 MPCs differentiate into hepatocytes and bile duct cells, as well as into fat, bone, cartilage, and en

101 In mature duct cells, Brg1 inhibits the dedifferentiation that pre

102 ated proliferation of mouse renal collecting duct cells but also increased the G2/S ratio, indicating

103 lpha 2 promoter activity in renal collecting duct cells but not in fibroblasts or in a medullary thic

104 n of activated LET-60/Ras in the neighboring duct cell, but not in the G1 or G2 cells, is sufficient

105 e were transplanted with cultured pancreatic duct cells, but no donor-derived hepatocytes were observ

106 nsplanted with cells enriched for pancreatic duct cells, but only three of the 34 (9%) recipients ana

107 ligation) and lineage-traced Ngn3-activated duct cells by labeling them through intraductal infusion

108 c analysis of rat inner medullary collecting duct cells by using a combination of phosphopeptide enri

109 n the secretion of bicarbonate by pancreatic duct cells, by transporting bicarbonate into the cell ac

110 ative signaling pathways in human pancreatic duct cells, cAMP-protein kinase A and mitogen-activated

111 and physiological features of the excretory duct cell, ces-2 and atf-2 mutants only exhibit anatomic

112 e specification of the intrahepatopancreatic duct cells, challenges the role of duct cells as progeni

113 re we showed that in mouse kidney collecting duct cells, claudin-4 functioned as a Cl(-) channel.

114 udy regulatory volume decrease (RVD) in bile duct cell clusters (BDCCs) from normal and cystic fibros

115 reduced RET activity, we find that Wolffian duct cells compete, based on RET signaling levels, to co

116 for ALGS ductal paucity.The hepatopancreatic duct cells connect liver hepatocytes and pancreatic acin

117 ssed in the apical membrane of submandibular duct cells, consistent with the significantly higher sal

118 yte-specific marker expression in pronephric duct cells correlates with loss of expression of the pro

119 Mouse renal proximal tubule and collecting duct cells, deficient in both pNBC1- and kNBC1-mediated

120 Furthermore, collecting duct cells derived from laminin-deficient kidneys and gr

121 ents phosphoproteomic findings in collecting duct cells describing the response to V2R-selective vaso

122 in primary mouse inner medullary collecting duct cells did not detect ENaC activity but did detect a

123 the proper expression of genetic markers of duct cell differentiation.

124 In vitro, Grhl2-deficient collecting duct cells displayed increased paracellular flux of sodi

125 By contrast, P2X7Rs in duct cells displayed only rapid gating by ATP.

126 ncipal cells, and inner medullary collecting duct cells do not.

127 n the LIN-48/Ovo transcription factor in the duct cell during morphogenesis.

128 r cells (MPCs) produce acinar, endocrine and duct cells during organogenesis, but their existence and

129 ctivity for prolactin, TGF-beta1, and EGF in duct cells during pregnancy and after CI, most prominent

130 ate a parallel mechanism operative in mature duct cells during which functional cells undergo "ductal

131 In cultured collecting duct cells, enhanced apical Na(+) entry increased the ba

132 +) availability in cultured mouse collecting duct cells, enhanced apical Na(+) entry invariably led t

133 tely isolated rat inner medullary collecting duct cells ex vivo and ET-1 peptide in rat inner medulla

134 C2, NEK8-depleted inner medullary collecting duct cells exhibited a defective response to fluid shear

135 AngII-treated inner medullary collecting duct cells exhibited augmented intracellular calcium sig

136 In knockdown experiments with pancreatic duct cells exposed to UV light, RNF43 appeared to functi

137 Pancreatic islet and duct cells express 25(OH)D(3)-1alpha-hydroxylase that ge

138 elective conditions revealed that acinar and duct cells express at least five distinct Cl- channels;

139 rescence analysis showed that SMG acinar and duct cells expressed NHE1 in the basolateral membrane (B

140 Bile duct cells expressed the LPS receptor, Toll-like recepto

141 es THM1) in mouse inner medullary collecting duct cells expressing an IFT88-enhanced yellow fluoresce

142 Collecting duct cells expressing this mutation had moderate abnorma

143 zation, convergent extension of the cochlear duct, cell fate specification, synaptogenesis, and the e

144 In kidney collecting duct cells, filamentous actin (F-actin) depolymerization

145 Thus, purified duct cells from adult human pancreas can differentiate t

146 ethylation was significantly reduced in bile duct cells from BA patients compared to patients with ot

147 In contrast, duct cells from heterozygous patients with R117H/DeltaF5

148 Collecting duct cells from mutant mice have abnormal primary cilia

149 Duct cells from patients with DeltaF508 mutant CFTR show

150 in PDACs and pancreatic cyst fluid and bile duct cells from the same patients.

151 ing pre-cystic renal tubule and hepatic bile duct cells from Tsc1, Tsc2 and Pkd1 heterozygous mice we

152 l NBCs in the HCO3- secreting SMG acinar and duct cells function as HCO3- salvage mechanisms at the r

153 unteers, pancreatic acinar cell, rather than duct cell, function is presently the single most signifi

154 ng integrin alpha3beta1-dependent collecting duct cell functions.

155 dneys provides limited insight of collecting duct cell gene expression, because these cells comprise

156 rogenitors that give rise to both acinar and duct cells, genetic ablation of SOX2 results in a failur

157 For example, sustentacular and duct cells give rise only to themselves after transplant

158 , PC1-depleted immortalized renal collecting duct cells had higher levels of integrin-beta1 and fibro

159 bud developed kidney agenesis and collecting duct cells had severe cytoskeletal, adhesion and polarit

160 Purified duct cells had slow expansion and poor aggregation, as w

161 Primary human pancreas duct cells harbouring oncogenic KRAS and induced mutatio

162 r sgk1-regulated ENaC activity in collecting duct cells has yet to be established.

163 ind that in mouse inner medullary collecting duct cells, high NaCl increases NTE mRNA within 8 h and

164 In cultured inner medullary collecting duct cells, HSP expression was maximal at 500 mOsm/kg, w

165 ls and spares immortalized normal pancreatic duct cells, hTERT-HPNE.

166 the constructs in inner medullary collecting duct cells (IMCD-3 cell line) and compared the subcellul

167 cal and functional features of the excretory duct cell in C. elegans result from the gain of expressi

168 o direct pathfinding of migrating pronephric duct cells in axolotl embryos by: (1) demonstrating that

169 Pax2 protein is present in collecting duct cells in both renal medulla and cortex and in thin

170 Strikingly, bile duct cells in cP(f/f)78(f/f) livers maintained wild-type

171 Dividing collecting duct cells in early stages of cyst formation fail to pro

172 Percentages of nonviable pancreatic duct cells in groups 1 to 5 were 3.8+/-2.7%, 59.7+/-4.4%

173 ells and in mouse inner medullary collecting duct cells in isotonic medium.

174 ructural and functional similarities to bile duct cells in normal liver.

175 Bile duct cells in pn demonstrated an accumulation of electro

176 plasma membrane of mouse cortical collecting duct cells in response to vasopressin.

177 tors in both pancreatic progenitor cells and duct cells in the adult pancreas.

178 nd that insulin(+) cells are continuous with duct cells in the epithelium that makes up the hyperplas

179 hepatocytes and proliferation of intra-islet duct cells in the pancreata of these mice evidently stem

180 TRIP13 in murine inner medullary collecting duct cells in the presence of hydrogen peroxide showed i

181 ein is predominantly localized to collecting duct cells in the rat kidney, with much lower expression

182 er medullary, and inner medullary collecting duct cells in vitro.

183 hing and cell cycle regulation in collecting duct cells in vivo Although in vitro data indicate that

184 nitors that produce exocrine, endocrine, and duct cells in vivo.

185 Here, we use phosphoproteomics in collecting duct cells in which PKA has been deleted (CRISPR-Cas9) t

186 the apical plasma membrane of rat collecting duct cells, in contrast to the other three phospho-forms

187 rog3, MafA, Pdx1 and Pax6 converted exocrine duct cells into endocrine progeny with hallmark beta-cel

188 vasopressin signaling network of collecting duct cells, involving several kinases not generally acce

189 ed aquaporin protein abundance in collecting duct cells is a contributing factor in the increased uri

190 e molecule at the apical surface of PBC bile duct cells is a modified form of PDC-E2 or a cross-react

191 V2-receptor mediated signaling in collecting duct cells is in part PKA-independent.

192 Therefore, Ngn3 activation in duct cells is not a signature for adult beta cell neogen

193 model, suggesting that activation of Ngn3 in duct cells is not sufficient to direct their transdiffer

194 changer at the apical membrane of pancreatic duct cells is now known to be SLC26A6.

195 of AQP2 in exosomes released from collecting duct cells is physiologically regulated and exosomal AQP

196 In mouse collecting duct cells, knockdown of KLHL3 profoundly increased the

197 Although cultured inner-medullary collecting duct cells lacked the gamma subunits, both variants gamm

198 a high resistance mouse cortical collecting duct cell line (94D).

199 scently loaded ECVs into a kidney collecting duct cell line (mCCDC11) and into primary cells.

200 terone in a mouse inner medullary collecting duct cell line and found that the transcript induced to

201 strated in the M-1 mouse cortical collecting duct cell line and in embryonic and adult mouse kidneys

202 or Phe-340 in the inner medullary collecting duct cell line IMCD.

203 zed this system further using the collecting duct cell line Madin-Darby canine kidney (MDCK), which r

204 nnels expressed in either a mouse collecting duct cell line or primary cultures of human airway epith

205 (iii) silencing of ZBED6 in the human PANC-1 duct cell line reduced proliferation rates; and (iv) ZBE

206 re performed in a murine cortical collecting duct cell line that endogenously expresses ENaC.

207 by using an unique mouse cortical collecting duct cell line that stably expresses functional mineralo

208 e developed an immortalized renal collecting duct cell line with inactive Pkd2; these cells had aberr

209 -mediated Na+ current in a kidney collecting duct cell line, although GILZ2 and GILZ3 also stimulated

210 vestigated in the cystic fibrosis pancreatic duct cell line, CFPAC-1.

211 also regulated ENaC in a cortical collecting duct cell line, mirroring the results in Xenopus oocytes

212 In the mPEC pancreatic duct cell line, where endogenous pNBC1 functions with a

213 and WNK1 were observed in a human collecting duct cell line, while SPAK was unaltered.

214 ormal rat cholangiocyte (NRC) polarized bile duct cell line.

215 t Notch ligands Jagged1b and Jagged2b induce duct cell lineage in the liver and pancreas of the zebra

216 ption factors that maintain the exocrine and duct cell lineages.

217 of Period 1 (Per1) mRNA in renal collecting duct cell lines and in the rodent kidney.

218 low, we generated inner medullary collecting duct cell lines that stably express enhanced green fluor

219 dent differentiation by infecting pancreatic duct cell lines with an Ngn3-expressing adenovirus.

220 table IMCD (mouse inner medullary collecting duct) cell lines, in which FPC was silenced by short hai

221 odels of Ngn3 activation in adult pancreatic duct cells (low-dose alloxan treatment and pancreatic du

222 yzed using specific endocrine, exocrine, and duct cell markers as well as markers for dividing cells.

223 whether Ngn3 activation in adult pancreatic duct cells may lead to duct-to-beta cell transdifferenti

224 In vivo, inner medullary collecting duct cells may regulate urea uptake by altering UT-A1 gl

225 l tubular epithelial and cortical collecting duct cells mediates the antidiuretic and cytoprotective

226 later time points, showed reduced acinar-to-duct cell metaplasia.

227 5 was demonstrated in mouse renal collecting duct cells (mIMCD-3) by RT-PCR and by immunocytochemistr

228 ures of polarized inner medullary collecting duct cells (mIMCD-3).

229 is in mouse renal inner medullary collecting duct cells (mIMCD3) and increases GADD45 expression.

230 bination on mouse inner medullary collecting duct cells (mIMCD3).

231 cells, inhibition of ERK phosphorylation in duct cells mitigated TGFbeta-induced upregulation of gro

232 ultured outer and inner medullary collecting duct cells (mOMCD1 and mIMCD3).

233 PDAC resembles duct cells morphologically and, to some extent, at a mol

234 ake of exosomes by renal cortical collecting duct cells, most studies of human urinary exosomes have

235 tor-mediated response in cultured collecting duct cells (mpkCCD) from mouse.

236 in mouse kidney and mouse kidney collecting duct cells (mpkCCD14).

237 By contrast, duct cell NBC3 transported both OH(-) and HCO3-.

238 erentially expressed in the serous acini and duct cells of all major salivary glands.

239 95% in acinar cells and greater than 80% in duct cells of NHE1-deficient mice (Nhe1(-/-)).

240 ted in autophagy failure specifically in the duct cells of salivary glands, followed by the accumulat

241 lomerular cells and HIF-1alpha in collecting duct cells of the adult kidney.

242 transcript was found in islet cells but not duct cells of the healthy pancreas.

243 ne and endothelin-1 (ET-1) act on collecting duct cells of the kidney and are important regulators of

244 B(2) receptor in inner medullary collecting duct cells of the kidney.

245 d current was measured in parotid acinar and duct cells of wild type and P2X7R-/- mice and in HEK293

246 ls of esophageal submucosal glands and their ducts, cells of the proximal stomach, and specialized po

247 habditis briggsae, but acts in the excretory duct cell only in C. elegans.

248 hought able only to generate hepatocytes and duct cells, only duct cells.

249 Duct cell P2X7Rs are preassembled and therefore continua

250 this gene specifically in kidney collecting duct cells prevents cilia formation and promotes rapid p

251 es sodium absorption across renal collecting duct cells primarily by increasing the apical membrane e

252 to characterize periductal fibrosis and bile duct cells progressing to CCA induced by inoculating O.

253 of embryogenesis, Prox1 appears to regulate duct cell proliferation and morphogenesis.

254 Additionally, significant intra-islet duct cell proliferation in the pancreata of transgenic K

255 d molecular changes that occur in acinar and duct cell properties on Kras(G12D) expression, we took a

256 located on the apical membrane of collecting duct cells, regulates water reabsorption under the contr

257 in pancreatic acinar and submandibular gland duct cells, respectively, evoke a Ca2+ signal by a mecha

258 raged 56 +/- 8 and 26 +/- 7 mM in acinar and duct cells, respectively.

259 II receptor deletion in cultured collecting duct cells resulted in excessive integrin alphavbeta6-de

260 lpha) s-coupled receptor (V2R) in collecting duct cells, resulting in increased water permeability th

261 ement of CFTR current in WT and slc26a6(-/-) duct cells revealed that deletion of slc26a6 resulted in

262 rane of aldosterone-stimulated A6 collecting duct cells revealed that the open probability of ENaC wa

263 g (Affymetrix) in mouse mpkCCDc14 collecting duct cells, revealing expression of 25 TRs that are also

264 ranes is consistent with the hypothesis that duct cells secrete the relatively high K+ in lacrimal fl

265 transport (NBC) activities in SMG acinar and duct cells showed separate DIDS-sensitive/EIPA-insensiti

266 We also show that SER in the duct cells signals to the adjacent secretory cells to sp

267 d mouse principal kidney cortical collecting duct cells significantly decreases cell motility.

268 tochemistry, however, showed that pancreatic duct cell-specific differentiation (carbonic anhydrase I

269 While the progenitor and duct cells started to proliferate and expand at 72 hours

270 AMP, cytosolic pH, and Ca2+ in isolated bile duct cells suggest that glybenclamide directly activates

271 n obligatory component in the maintenance of duct cell survival, proliferation, and migration during

272 K(ATP) channel is present in salivary gland duct cells that is regulated by extracellular ATP and po

273 human liver (including hepatocytes and bile duct cells), the major enzyme is ACAT1, rather than ACAT

274 In the collecting duct cells, the assembly of claudin-4 into TJ strands re

275 -:1 Na+ stoichiometry, whereas in collecting duct cells, they have a 2:1 stoichiometry.

276 use deep DNA sequencing in mouse collecting duct cells to ask whether vasopressin signaling selectiv

277 ssion and also decreased sensitivity of bile duct cells to calcium agonist stimuli.

278 d in isolated submandibular gland acinar and duct cells to characterize and localize the purinergic r

279 he transcellular Cl- transport by acinar and duct cells to determine the final electrolyte compositio

280 opressin through actions in renal collecting duct cells to regulate the water channel protein aquapor

281 Here we used parotid acinar and duct cells to reveal the unique cell-specific assembly a

282 , we used cultured mouse cortical collecting duct cells to see how overexpression or silencing of epi

283 iates its effects in one cell (the excretory duct cell) together with another bZip protein, ATF-2.

284 ells, which can give rise to both acinar and duct cell types in the murine salivary glands.

285 n in the thick ascending limb and collecting duct cell types.

286 n mouse principal kidney cortical collecting duct cells using a GST-SNX27 fusion construct as bait.

287 thylated in microdissected normal pancreatic duct cells using bisulfite-modified sequencing and in tw

288 s was detected within the graft's collecting duct cells using quantitative polymerase chain reaction

289 alivary submandibular gland (SMG) acinar and duct cells was used to evaluate the role of Cl- channels

290 ll mice, which consists of only exocrine and duct cells, was subtracted from fetal wild-type pancreas

291 inuous cultures of intermedullary collecting duct cells were exposed to various levels of oxalate, a

292 ure cotransporter activity, mouse pancreatic duct cells were grown to confluence on a porous substrat

293 ermore, ptip null inner medullary collecting duct cells were sensitive to hyperosmolality in vitro.

294 m-specific, renal inner medullary collecting duct cells were stably transfected with cDNA's encoding

295 in is expressed in cultured mouse collecting duct cells, where apical Na(+) transport is mediated by

296 are expressed on the basolateral membrane of duct cells, whereas KCC1, IK(Ca)1, CFTR, and ClC3 are ap

297 NHE2 to apical membranes of both acinar and duct cells, whereas NHE3 was restricted to the apical re

298 ch are responsible for saliva formation, and duct cells, which modify the saliva and conduct it to th

299 omplete loss of canonical Notch activity and duct cells within the liver and exocrine pancreas, where

300 fficking of polycystins in kidney collecting duct cells without affecting protein levels or cilia.