ライフサイエンスコーパス: early development

1 l and functional network connectivity during early development.

2 NMT that methylates mammalian genomes during early development.

3 s paired endomesodermal cell clusters during early development.

4 n overlapping function that is essential for early development.

5 egging Effort required to obtain food during early development.

6 from ensembles of LGN neurons in cats across early development.

7 oogenesis, cleavage-stage embryogenesis and early development.

8 hromosome inactivation is established during early development.

9 f higher-order chromatin architecture during early development.

10 netic screens to uncover genes necessary for early development.

11 and the spreading of embryonic tissue during early development.

12 cells but promoting pre-BCR signaling during early development.

13 h their impact on wasp colony initiation and early development.

14 aly, cortical thinning, and blindness during early development.

15 on guidance or neuron differentiation during early development.

16 EM) sleep, a particularly prominent state in early development.

17 ialized functions with the microbiota and in early development.

18 activation of lineage specifying TFs during early development.

19 is critical for successful fertilization and early development.

20 otipotency-to-pluripotency transition during early development.

21 uscle and peripheral nerve patterning during early development.

22 stress the importance of local TH action in early development.

23 fitness measures differed between stages of early development.

24 and cell cycle progression anomalies during early development.

25 oordinated to regulate RNA metabolism during early development.

26 roRNAs may therefore play important roles in early development.

27 ereby demonstrating its potential utility in early development.

28 asticity independently from their effects on early development.

29 tages, including cotton fiber initiation and early development.

30 rgence in the regulation of pluripotency and early development.

31 ranscription of neural-specific genes during early development.

32 nome organization and gene expression during early development.

33 ne enhancers during the phylotypic period of early development.

34 s that are established stochastically during early development.

35 normal neurophysiology, particularly during early development.

36 synaptic proteins and those expressed during early development.

37 potent states is important for understanding early development.

38 gulates muscle integrity and function during early development.

39 e effects of environmental pollutants during early development.

40 amily of formins, plays an important role in early development.

41 on of in-group members seems to be rooted in early development.

42 fully innervate the lateral rectus muscle in early development.

43 GVBD) and is critical for oocyte quality and early development.

44 ncrease of oligodendrocyte precursors during early development.

45 The tumor suppressor PTEN is essential for early development.

46 he spindle also scales with cell size during early development.

47 t1 and Tet2 during cell state transitions of early development.

48 ic components of breast milk that may affect early development.

49 th tissues, cell survival was maximal during early development.

50 nly rescued when Ube3a was reinstated during early development.

51 red for activation of Cdx2 expression during early development.

52 inetics and dictates size scaling throughout early development.

53 que response to telomere deprotection during early development.

54 erapeutic targets that coordinately regulate early development.

55 sses that occur during axial organization in early development.

56 cesses that underlie chiral morphogenesis in early development.

57 3 knock-out mice suggests it is critical for early development.

58 ic landscape during cell fate transitions in early development.

59 sponse is active in invertebrate larvae from early development.

60 d function of the Hippo pathway in mammalian early development.

61 Ns identifies how novelty is incorporated in early development.

62 cell genes that are normally silenced during early development.

63 gested conserved principles of pig and human early development.

64 with promoters in the gametes persist during early development.

65 ndicator of cardiac autonomic control during early development.

66 astrocyte-neuron communication absent since early development.

67 pographic representations are refined during early development.

68 criptional level of BR regulation of soybean early development.

69 association and was essential for zebrafish early development.

70 Frontal fiber tracts displayed deviant early development and age-related changes that could und

71 ng all NMDAR transmission are viable through early development and are capable of a wide range of ste

72 ed plasticity to stress exposure, such as in early development and at advanced age; and, second, the

73 ric neural tumors are often initiated during early development and can undergo very rapid transformat

74 Rapid cellular proliferation in early development and cancer depends on glucose metaboli

75 ffects that follow signaling cascades during early development and cell-restricted differentiation.

76 opens up new possibilities for the study of early development and developmental disorders, but it ma

77 ence between cervical loop morphology during early development and differentiation of odontoblasts th

78 Loss of cpa leads to lethality in early development and expression of the human reference;

79 In humans, however, the early development and function of T cells in tissues rem

80 s showed enrichment of genes associated with early development and function of the nervous system.

81 eterogeneity in cell function emerges during early development and how structural patterning goes han

82 ynamic chromatin regulatory landscape during early development and identifies key transcription facto

83 xtracellular matrix of the myocardium during early development and in the aftermath of a myocardial i

84 dows, hypoxia reduced copper toxicity during early development and increased its toxicity in hatched

85 family of postsynaptic MAGUK proteins during early development and is proposed to play a role in stab

86 Our characterisation of the early development and maturation of pyramidal neurons in

87 n, decoding extracellular cAMP pulses during early development and may play a role in mediating cell-

88 Neochrome b and violaxanthin accumulated at early development and started to decrease two weeks befo

89 ntribute to deeper understanding of organism early development and survival as well as cancer.

90 Arf6 activation through GluN2B-BRAG1 during early development and the transition from BRAG1- to BRAG

91 Progenitors divide rapidly during early development and their cell cycle lengthens progres

92 sion in neurons to extracellular cues during early development and throughout life.

93 e reduction of Gram-positive bacteria during early development and thus to a spatial distribution of

94 trin 3 declines significantly in CNS through early development and young adulthood before stabilizing

95 id stem cell homing and proliferation during early development and/or wound repair.

96 and central nervous system, strongest during early development, and decreasing postnatally.

97 t role for exuberant brain plasticity during early development, and for constraints that are imposed

98 rsely, topo-II levels were unchanged through early development, and partial topo-II depletion led to

99 emosensory knowledge of their parents during early development, and retain chemical familiarity with

100 During early development, animal embryos depend on maternally d

101 the effects of beta-catenin/Wnt signaling in early development are exquisitely regulated by stage-dep

102 Light-dependent functions in early development are mediated by intrinsically photosen

103 cells confirming their exclusive role during early development as previously reported by our laborato

104 The oviduct plays a central role in early development as the site of gamete transport, synga

105 ontextual susceptibility appear to emerge in early development, as the interactive and adaptive produ

106 After early development, astrocyte mGluR5 expression is downre

107 We found that, in early development, auxiliary alpha2delta3 subunits of ca

108 in cortical bone quality and strength during early development (bone modeling) that persist during ad

109 D) model promises a greater understanding of early development but has left unresolved the balance of

110 ll to multicellular behavior is important in early development but rarely studied.

111 thologue, Appb, is strongly expressed during early development but thus far has only been studied via

112 rals transiently control circuit assembly in early development, but it is thought that PC-to-PC conne

113 ption 3 (Stat3) plays important roles during early development, but it is unclear how Stat3 is activa

114 observed postures and movement timing across early development, but only when locomotor-driven stabil

115 in boundary formation and neural guidance in early development, but which is also expressed in a rang

116 Stored lipids fuel early development, but with adulthood comes changing met

117 Experiences during early development can influence neuronal functions and m

118 ), and incomplete epigenomic defenses during early development can lead to deleterious TE mobilizatio

119 ft mouse models and has been evaluated as an early development candidate.

120 es demonstrated that NKCC1 inhibition during early development caused a broad remodeling of the prote

121 conditional knockout of neuroligin-3 during early development caused no detectable effect, mimicking

122 Lead exposure during early development causes neurodevelopmental disorders by

123 hort study, we used data from the Australian Early Development Census (AEDC) that were probabilistica

124 ar re-programming results in deregulation of early development checkpoints culminating in inefficient

125 f the bacterial microbiome and virome during early development, conditions that might influence these

126 th global demethylation and remethylation in early development correlate with chromatin compartments.

127 thrombosis, genes initially characterized in early development could also play an important role in h

128 onale, medicinal chemistry, preclinical, and early development data of this new class of GPR40 agonis

129 Acute genetic disruption in early development, during the integration of post-embryo

130 During early development, extrinsic triggers prompt pluripotent

131 Specifically, BPA reduces growth during early development, followed by a catch-up growth post-ju

132 ccess to human material, particularly during early development, has restricted researchers to only sc

133 SPNs during early development have high intrinsic excitability and r

134 s the site of gamete transport, syngamy, and early development; hence, accelerated ageing of the ovid

135 ormula-fed girls from the Infant Feeding and Early Development (IFED) study.

136 l as it reduces mitochondrial segregation in early development, improving adult fitness by restrictin

137 atures during the 1st year of life constrain early development in 71 healthy typically developing inf

138 species (ROS), which occurs naturally during early development in a subpopulation of synchronized Cae

139 drastic elimination of serum/LIF ESCs during early development in comparison with 2i/LIF ESCs.

140 deficiency in neurotrophin signaling during early development in FXS.

141 ranscriptional repression established during early development in many eukaryotes.

142 programming of chromatin organization during early development in mice.

143 To study aberrations of early development in TSC, we generated induced pluripote

144 We find that E2a regulates early development in two ways.

145 omprehensively studying Ezh2 function during early development in vertebrates.

146 ave begun to define a critical period during early development in which disruption of optimal host-co

147 cs of spontaneous vertical locomotion across early development in zebrafish (Danio rerio) .

148 We demonstrate that early development in zebrafish embodies a time window ch

149 ere, we developed a model to study NMDARs in early development in zebrafish, by generating CRISPR-med

150 ces for millennia, yet little is known about early developments in mineral processing techniques in N

151 Novel interventional approaches in early development include carotid body ablation and arte

152 ll, zygotic exposure to venlafaxine disrupts early development, including brain function, and comprom

153 mbryonic exposure to venlafaxine accelerated early development, increased hatching rate and produced

154 al overnutrition during sensitive periods of early development increases the risk for obesity and neu

155 ise clinically healthy population sample, in early development, individual differences in compulsivit

156 Exposure to a xenobiotic during early development induced persistent fat accumulation vi

157 Tet1 gene are differentially expressed from early development into adulthood.

158 Fruit formation and early development involve a range of physiological and m

159 The attenuation of plasticity beyond early development is a formidable obstacle for conventio

160 odel in which nuclear size regulation during early development is a multi-mode process wherein nucleu

161 principle in biology is that the program for early development is established during oogenesis in the

162 Early development is governed by the ability of pluripot

163 d the molecular mechanism underlying soybean early development is largely unexplored.

164 Most early development is necessarily dyadic and intrinsicall

165 essential during mammalian embryogenesis and early development is one of the key activators of mTORC1

166 CRH hyper-signaling in the forebrain during early development is sufficient to increase response to

167 chiatric illnesses; however, its role during early development is unclear.

168 During early development, knock-outs were indistinguishable fro

169 d a greater likelihood of motor delay during early development (later age at walking), but they were

170 rchestrated by Xist RNA, whose expression in early development leads to transcriptional silencing of

171 ion typically occurs in somatic cells during early development, leaving the germline genome intact.

172 as fertilisers, as the inhibitory effects on early development may outweigh any benefits if the conce

173 ystems, such as isolated cell populations or early-development models.

174 morphology and circuitry established during early development must often be maintained over the enti

175 tochondrial respiration and that patterns of early development need to be considered when studying th

176 During early development, neurotransmitters are important stimu

177 R-92b, and miR-210, might be involved in the early development of a Th2 response in the airways and a

178 f metabolic single-cell heterogeneity during early development of a vertebrate embryo.

179 biotics might have a preventive role against early development of AD and that therapeutic approaches

180 n skin barrier function before or during the early development of AD is not fully understood.

181 ls, suggesting the involvement of miR-195 in early development of AD with a potential impact on cogni

182 High-resolution data regarding early development of allergen-specific IgG are needed.

183 regenerated skeletal structures, indicating early development of an approximate PD pre-pattern.

184 -standard toxicity models is a hurdle in the early development of antimicrobial peptides towards clin

185 nation and modulate root architecture during early development of Arabidopsis seedlings.

186 risk of autism can provide insight into the early development of autism and have shown that characte

187 differs on a millisecond-level scale in the early development of autism spectrum disorders (ASD).

188 tion of the immune system in controlling the early development of cancer and establish a fundamental

189 dence linking ATF3 to the suppression of the early development of cancer, and underscore the importan

190 Chronic anterior uveitis, vitritis, early development of cataract, and the absence of poster

191 In MSA, severe dysautonomia and early development of combined autonomic and motor featur

192 Early development of constipation and urinary symptoms w

193 Our study revealed a high prevalence and early development of de novo DSA and non-DSA (43%, the m

194 amyloid (Abeta) toxicity can precipitate the early development of dementia.

195 ted by memory phenotypes was associated with early development of donor-specific antibodies in 4 of 5

196 While the early development of emotional problems was associated w

197 Studies of GRNs operating in the early development of euechinoid sea urchins have reveale

198 His professional life coincided with the early development of general and thoracic surgery to whi

199 ponse after ocular HSV-1 infection causes an early development of herpes stromal keratitis in NK1R(-/

200 osines at CpG sites plays a critical role in early development of humans and other mammals.

201 es beta-cell failure and diabetes, including early development of hyperproinsulinemia.

202 two kinase-inactive RLKs, in controlling the early development of lateral root primordia likely via r

203 This investigation evaluated the early development of lateralised gaze behaviour for face

204 interventions that reduce the likelihood of early development of lifelong diabetes-related morbidity

205 of shaping the research agenda and promoting early development of long-acting or extended release pro

206 ate how socio-cognitive constructs influence early development of mathematical skills.

207 that indicates the predisposition towards an early development of metabolic syndrome in ca. 25% of he

208 Npc1(nmf164) mice significantly affected the early development of microglia by delaying the radial mi

209 nsory area by developing early, and that the early development of MT may influence the subsequent dev

210 of a tumor suppressor gene that lead to the early development of multifocal benign neoplasms followe

211 us variable and sex, clinical phenotype, and early development of neurological and autonomic manifest

212 ting effects of gliosis should be applied in early development of novel therapeutics, in particular f

213 Early development of obesity predicted obesity in adulth

214 ak is likely to improve our understanding of early development of obesity.

215 n these index cases support a model in which early development of occult hippocampal hyperexcitabilit

216 Several studies have documented the early development of OHC electromechanical behavior.

217 The early development of our hypothesis focuses on an iridiu

218 an important source of nutrients during the early development of oviparous organisms.

219 w component of ABA signaling which modulates early development of plant by precisely controlling ABI5

220 eased incretin responses likely leads to the early development of postprandial hyperglycemia in CF.

221 at innate immunity is a leading actor in the early development of pulmonary changes in smoking mice a

222 eas of NK1R(-/-) mice was associated with an early development of severe herpes stromal keratitis.

223 intact embryonic skull, which indicates the early development of stereoscopic vision, and an unusual

224 re we investigated the role of n1-src in the early development of the amphibian Xenopus tropicalis, a

225 of the somatic and neural elements following early development of the central nervous system.

226 with the promoters of genes involved in the early development of the central nervous system.

227 The functions of FGF receptors (FGFRs) in early development of the cerebral cortex are well establ

228 togenic mesodermal and ectodermal domains in early development of the cidaroid Eucidaris tribuloides

229 Here we show that Sia is dispensable for early development of the embryo proper but pivotal for f

230 ges and rapidly decreasing cell sizes during early development of the embryo.

231 Early development of the endosperm in Austrobaileya is a

232 ors and I were enthused to contribute to the early development of the field and continue to be amazed

233 ogeneous catalysts, has been made during the early development of the field and in recent years.

234 uggestive of a Shh-Vax1 feedback loop during early development of the forebrain and a likely mechanis

235 ffspring, potentially through its effects on early development of the infant microbiome.

236 slate into cell division activity during the early development of the organ.

237 ior portion of the right CB may underlie the early development of the preterm behavioral phenotype.

238 ned the function of nbeta-catenin during the early development of the sea star, which undergoes a bas

239 vation of GRN architecture was maintained in early development of the sea urchin lineage.

240 othelial and hematopoietic precursors during early development of the vascular system suggested the p

241 ation of Cd and Hg to female mice during the early development of their offspring (the periconception

242 f Cd and Hg that were co-administered during early development on indices of chronic diseases in adul

243 can map specific gene expression patterns in early development onto specific point attractor patterns

244 During early development, PGCs are exposed to numerous signals

245 re still under clinical evaluation or in the early development phase.

246 to test whether social positions held during early development predicted adult fitness.

247 ound that these enhancers were permissive in early development prior to Pmp22 upregulation.

248 this short period of the GH exposure during early development produces persistent phenotypic, metabo

249 Exposure to maternal obesity during early development programmes adverse metabolic health in

250 become an integral part of how research and early development (R&D) is executed in biotech companies

251 ensitivity is evident in multiple periods of early development, ranging from the first trimester of g

252 ptic influences from sensory synapses during early development regulates the density and organization

253 the embryo and how cell cycle timing impacts early development remain important, unanswered questions

254 onic development in mammals, its role during early development remains controversial.

255 heterochromatin is assembled de novo during early development remains poorly understood.

256 t an induced burst of DUX4 expression during early development results in the onset of FSHD-like phen

257 nscription-repressing heterochromatin during early development safeguards genome integrity in Drosoph

258 rs that fashion TL in somatic tissues during early development should contribute to an understanding

259 Additionally, Lgdel (+/-) networks at early development show abnormal neuritogenesis and void

260 organism is exposed to pathogens during very early development, specific defense mechanisms must take

261 During early development, SR-BI is expressed in extraembryonic

262 of cucumber plants in hydroponic culture at early development stages to two concentrations of nano-C

263 es indicate that adult tissues contain rare, early-development stem cells known as very small embryon

264 ce of target diseases and the stage at which early development studies should be focused.

265 (age 19-21) from the UK-representative Twins Early Development Study (TEDS).

266 1,265 twin pairs from the Twins Early Development Study completed the novel "Bricks" tes

267 366 dizygotic (DZ) twin pairs from the Twins Early Development Study from age 12 to age 21.

268 scent twins (18-19-years old) from the Twins Early Development Study were used to quantify genetic an

269 2865 twins aged 18-19 y from the TEDS (Twins Early Development Study), a large population-based cohor

270 Participants were drawn from the Twins Early Development Study, a population-based cohort recru

271 ive sample of 8395 twin pairs from the Twins Early Development Study, recruited from population recor

272 1,215 18-year-old twin pairs from the Twins Early Development Study, we collected measures of two in

273 data from the population-based cohort Twins Early Development Study, which included all twin pairs b

274 twin pairs from the UK representative Twins Early Development Study.

275 16 years in 10,038 twin pairs from the Twins Early Development Study.

276 and myelin was seen in the lateral column in early development, suggesting that there may also be a r

277 Here we report that, during early development, superficially positioned Reelin-expre

278 body of evidence implicates perturbations in early development that alter the trajectory of brain mat

279 erience site-specific thermal regimes during early development that could be disrupted by warming.

280 ral cycles of rapid furrow ingression during early development that culminate in the formation of an

281 still remains unclear during which phases of early development the offspring is more vulnerable.

282 precisely timing CRISPR-Cas9 delivery during early development, the degree of pigmentation could be f

283 Thus, together with its role in early development, the dynamic regulation of m(6)A in th

284 terized role in stem cell biology and during early development, the role of PRDM15 in cancer remains

285 Here, we show that during early development, the sea urchin ANE territory separate

286 During early development, these interneurons undergo long-range

287 Building on lessons taken from early development, this monolayer-directed differentiati

288 n formation of the nervous system, from very early development through adolescence.

289 from convergent-extension mechanisms during early development through to terminal organogenesis, and

290 sent in mouse hypothalamic POMC neurons from early development to adulthood.

291 the thioredoxin DHD plays a critical role in early development to facilitate the switch from protamin

292 They are transcriptionally silenced during early development to protect genome integrity and aberra

293 rament, and chronic adversity combine across early development to shape the human empathic brain.

294 ural cells investing the dorsal aorta during early development using the zebrafish.

295 that the reduction in copper toxicity during early development was independent of copper uptake, whil

296 Sox2, the key regulator of pluripotency and early development was significantly reduced.

297 on the suppression of copper toxicity during early development, we stabilized the hypoxia inducible f

298 peak capacity for a body system, starting in early development when plasticity permits changes in str

299 ng nucleus size is a particular challenge in early development, where the nucleus must downscale in s

300 transiently blunted emotional reactivity in early development, with latent fear-associated memories