ライフサイエンスコーパス: early differentiation

1 e accessible within pre-existing TADs during early differentiation.

2 etylation also alters gene expression during early differentiation.

3 yonic mammalian hair cells but not for their early differentiation.

4 cells, which undergo a binary choice during early differentiation.

5 ly regulated activation of NF-kappaB but not early differentiation.

6 d induced dysregulation of genes involved in early differentiation.

7 e multinucleated osteoclasts, but not during early differentiation.

8 r during their specification, migration, and early differentiation.

9 se TopoVelo to study the spatial patterns of early differentiation.

10 ncluding enhancers regulating key factors in early differentiation.

11 ors that control pluripotent identity during early differentiation.

12 lution of primed pluripotent identity during early differentiation.

13 5a-facilitated endocytosis rescues defective early differentiation.

14 d their enhancers are most accessible during early differentiation.

15 nvolved in the LESC maintenance and/or their early differentiation.

16 for a specific task related to stemness and early differentiation.

17 or cell cycle progression, pluripotency, and early differentiation.

18 sion of developmental genes and induction of early differentiation.

19 numbers of inactivated X chromosomes during early differentiation.

20 s (ESCs), which change shape as they undergo early differentiation.

21 ature of Earth's heterogeneous accretion and early differentiation.

22 vitro, along with upregulation of markers of early differentiation.

23 triggered increase in endocytosis regulates early differentiation.

24 ell fusion, none of the treatments prevented early differentiation.

25 kely because of an ASC-sensitive block(s) in early differentiation.

26 competence is acquired only gradually during early differentiation.

27 t are repressed in ESCs and derepressed upon early differentiation.

28 xpressed gene in the vascular lineage during early differentiation.

29 of involucrin, consistent with promotion of early differentiation.

30 During early differentiation (14 hours to 1 day after BrdU), re

31 th-defying phenotype of KCs does not require early differentiation; 5) NF-kappaB is one regulator of

32 to identify 69 genes altered by IRF-8 during early differentiation (62 up-regulated and 7 down-regula

33 -regulated opposition to pluripotency during early differentiation, a process highly distinct from st

34 ast, contains cells that are maturing toward early differentiation and are likely transit-amplifying

35 entifies ICSBP as a factor critical for both early differentiation and final maturation of DCs.

36 express the transcription factor MafB during early differentiation and maintain calbindin expression

37 Yet, the genetic mechanisms underlying early differentiation and patterning of the cerebellum a

38 rventions, we show that RORA is required for early differentiation and prevents diHSCs activation by

39 Early differentiation and regular spacing of the precoci

40 +) T cell clonotypes displayed signatures of early differentiation and stemness associated with natur

41 an oligodendroglia circRNA landscapes during early differentiation and suggest critical roles of the

42 ses define a specific role for both genes in early differentiation and survival of the placodally der

43 properties of silicate melts, affecting the early differentiation and the dynamic stability of the m

44 zed with respect to markers of pluripotency, early differentiation, and cellular health.

45 ling promoted osteoprogenitor proliferation, early differentiation, and commitment to the osteoblasti

46 e-specific matrix genes that are silenced in early differentiation are expressed during the terminal

47 Controls of stem cell maintenance and early differentiation are known in several systems.

48 immature T-ALLs are characterized by a very early differentiation arrest and show unique genetic and

49 It is characterized by an early differentiation arrest in the myeloid lineage, imp

50 ve patient risk stratification and may allow early differentiation between competing therapies during

51 eliable biomarker is needed for accurate and early differentiation between Parkinson disease and the

52 Therefore, early differentiation between SLC34A1 (NaPi-IIa) and CYP

53 nsable for osteoblast lineage commitment and early differentiation but also blocks osteoblast maturat

54 rvoirs showed that strong coupling supported early differentiation but required a higher number of ba

55 pads of cKO mice indicated no difference in early differentiation, but instead markedly lower leptin

56 ed intrinsically in the germ cells for their early differentiation, but is required in the germ cells

57 ars is thought to hold clues to the planet's early differentiation, but until now no meteoritic regol

58 promoting ESC attachment, proliferation, and early differentiation, compared to native EB and decellu

59 Characterization of an early differentiation defect, the multiple-R8 phenotype,

60 ng a decrease in membrane tension results in early differentiation defects in ESCs and gastruloids.

61 alpha/beta caused a significant reduction in early differentiation-dependent increases in DUX4 and DU

62 gulation of key differentiation genes during early differentiation depends on the dynamic balance bet

63 se of only approximately 15% decrease during early differentiation despite global changes in gene exp

64 aging and gene expression profiling to study early differentiation dynamics spontaneously occurring w

65 nd various other features of this important, early differentiation event.

66 am of egl-5 to direct HSN cell migration, an early differentiation event.

67 n through the cell cycle and that these very early differentiation events do not require the accumula

68 ce promotes proliferation of osteoblasts and early differentiation events like production of alkaline

69 Studying these early differentiation events may help to identify specif

70 tive surfaces; conidia germinate and undergo early differentiation events, but appressorium maturatio

71 e undergo distinct expression changes during early differentiation events.

72 phocyte precursors and suggest a sequence of early differentiation events.

73 6-cell cysts, bridging the expression of the early differentiation factor Bam with late markers such

74 n, probably by inhibiting the translation of early differentiation factors, whereas niche signals pre

75 tinct stages of OL development, accelerating early differentiation followed by decelerating maturatio

76 f adult hippocampal newborn cells die during early differentiation from intermediate progenitors (IPC

77 tered early activation kinetics and impaired early differentiation gene expression, including upregul

78 involved in epidermal differentiation, with early differentiation genes (KRT1, KRT10, DSC1, DSG1) be

79 that distinguish tonsil BCs from tonsil PCs (early differentiation genes [EDGs]), and tonsil PCs from

80 The molecular mechanisms controlling SM early differentiation have been studied extensively.

81 With early differentiation, hPSC proliferation slows, energy

82 The effects of Nodal on early differentiation illustrate how hESCs can augment m

83 2F2 in the activation of neural genes during early differentiation in humans.

84 sassembly in the control of Hh signaling and early differentiation in muscle cells.

85 ratinocyte proliferation, stratification, or early differentiation in skin.

86 CPCs undergoing early differentiation in vitro increase levels of CaMKII

87 adhesion, adherens junction composition, and early differentiation in vivo and in vitro.

88 d of endothelial cells expressing markers of early differentiation, including VEGFR2 (Flk1), Tal1/SCL

89 embryonic stem cells (hESCs) in response to early differentiation, induced by retinoic acid, versus

90 adipocytes to PGF2alphaEA/bimatoprost during early differentiation inhibits adipogenesis.

91 The constancy of Zn/Fe(T) during early differentiation involving olivine requires that Fe

92 rom stem cell self-renewal to overt signs of early differentiation is a poorly understood but importa

93 bitors (p15, p16, p21, and p27), a marker of early differentiation (keratin 1), mediators of apoptosi

94 cross-sectional sample and characterized by early differentiation kinetics.

95 rly activation, higher ISG expression during early differentiation, maintenance of IL2Ralpha expressi

96 inal differentiation program, stimulating an early differentiation marker (keratin 1) and suppressing

97 suggests that 9-O-acetylation appears as an early differentiation marker as cells mature from the DP

98 number of basal keratinocytes expressing the early differentiation marker keratin 1 (K1).

99 tors unexpectedly increased the synthesis of early differentiation marker protein delta-crystallin in

100 d by expression of the gene encoding for the early differentiation marker, Myogenin.

101 Early differentiation markers are abundantly expressed i

102 rmally transitory state where progenitor and early differentiation markers are co-expressed.

103 Expression of early differentiation markers is RBP-Jkappa-independent

104 Induction of p21WAF1/Cip1 expression and early differentiation markers occur through two differen

105 NOTCH3 (N3) transcription, inducing HES5 and early differentiation markers such as involucrin (IVL) a

106 rogram characterized by normal expression of early differentiation markers such as myogenin and p21,

107 s encoding general cell growth functions and early differentiation markers was not affected, suggesti

108 D34(+) cells were equivalent with respect to early differentiation markers, and following culture, th

109 ein levels of some cell cycle regulators and early differentiation markers.

110 ptional misregulation of TSC maintenance and early differentiation markers.

111 cation correlated with delayed expression of early differentiation markers.

112 Activated Notch1 also induces expression of 'early' differentiation markers, while suppressing the la

113 derlying the switch between self-renewal and early differentiation may be acting in these two pools.

114 reas the transition between self-renewal and early differentiation modes of the network underlies the

115 ates the role of Akt and Clk1 kinases in the early differentiation of 3T3-L1 cells to adipocytes.

116 ess exposure increased the proliferation and early differentiation of adult neural progenitor cells.

117 While early differentiation of adult radial glia-like cells (R

118 correlates temporally and spatially with the early differentiation of angioblasts into the endothelia

119 s of osteogenesis prematurely and led to the early differentiation of bone.

120 riter complex proteins, is essential for the early differentiation of both human and mouse pancreatic

121 search is needed to develop tools that allow early differentiation of bvFTD from primary psychiatric

122 We studied the early differentiation of calcium release units, which me

123 o create a precise genetic definition of the early differentiation of cap mesenchyme progenitors.

124 clear kinase that plays an essential role in early differentiation of cardiomyocytes.

125 ide evidence to show that MAIT cells promote early differentiation of CCR2-dependent monocytes into m

126 d and sufficient for maturation, but not for early differentiation of CMs.

127 Accurate, early differentiation of dementias will become increasin

128 host dendritic cells (DCs) and that there is early differentiation of donor-derived DCs, even after t

129 ets, provides insight into the formation and early differentiation of Earth.

130 clusions, indicating involvement of MYO5B in early differentiation of epithelial cells.

131 expression and then orchestrates RA-induced early differentiation of ESCs.

132 e conclude that stat92E is necessary for the early differentiation of follicle cells and for proper g

133 an effect on the generation, migration, and early differentiation of granule cells.

134 of eukaryotic initiation factor 3 (eIF3) in early differentiation of human pluripotent stem cell (hP

135 nd myosin light chain 2a in real-time during early differentiation of human pluripotent stem cells.

136 ding a lincRNA, that was up-regulated during early differentiation of human Tregs.

137 expression of Wnt3a in the neocortex induced early differentiation of IPs into neurons and the accumu

138 rganization of cytoskeleton signaling during early differentiation of LR muscle cells.

139 s play a role in efficient commitment and/or early differentiation of most T progenitors.

140 4 loss on chromatin and transcription during early differentiation of mouse embryonic stem cells.

141 to the myocardium is crucial for initiating early differentiation of myocardial cells.

142 We explored the early differentiation of naive CD4 T helper (Th) cells i

143 Thus, the early differentiation of naive diabetogenic T cells into

144 statistical structure was accompanied by an early differentiation of neural activity for relevant co

145 velopment and suggest that TWH regulates the early differentiation of neural progenitors.

146 1), which is localized in the nucleus during early differentiation of odontoblasts, is able to bind s

147 The early differentiation of olfactory structures and the pe

148 en postulated to play a critical role in the early differentiation of oligodendrocytes (OLs) in addit

149 est that proliferation, cell cycle exit, and early differentiation of primary lens fiber cells are re

150 a mutation in valentino (val), which blocks early differentiation of rhombomeres 5 and 6 in the hind

151 ical connectivity during infancy reflects an early differentiation of sensorimotor networks and genet

152 GATA factors, ZFPM1 is not essential for the early differentiation of serotonergic precursors in the

153 the nuclear localization of SOX9 during the early differentiation of Sertoli cells and the determina

154 sfer to inductive medium and potentiates the early differentiation of some cells.

155 Prox motif and TBK1 were dispensable for the early differentiation of TFH cells.

156 d models provide an opportunity to model the early differentiation of the developing human cerebellum

157 promoter based upon the role of keratin 4 in early differentiation of the esophageal squamous epithel

158 veal a novel role for mesodermal Fgf8 on the early differentiation of the NC along the parasympatheti

159 hese two genes has specific consequences for early differentiation of the primary olfactory pathway-w

160 studies imply that Sox9 is required for the early differentiation of the prostate bud epithelia.

161 ial cell types and could also be involved in early differentiation of the skeleton and kidney.

162 e TGF-beta-triggered pathways that drive the early differentiation of these cell populations.

163 (ATRX and TSPAN2) as possible biomarkers for early differentiation of ultra-high risk, bipolar and he

164 in the steps of cell fate determination and early differentiation of various retinal cell types.

165 that arginine methylation might regulate the early-differentiation of effector-memory CD4+ T-cells fo

166 To compare the role of FAS during early differentiation or survival of Tmem in chronic inf

167 These results suggest that during the early differentiation process CD4 T cells acquire a mixe

168 hology, suggesting that they are involved in early differentiation processes common to all plants.

169 of s-process neodymium in the Earth, and not early differentiation processes.

170 l a developmental clock characteristic of an early differentiation program common to all EBs, further

171 This early differentiation program depends on both the stepwi

172 uggesting that TopIIbeta is not required for early differentiation programming but is specifically re

173 ogenitors by regulating the transcription of early differentiation programs.

174 y virtue of the ability of Notch to suppress early differentiation-promoting factors in NSC progeny.

175 during stem cell pluripotency transition and early differentiation provide orthogonal support for an

176 in the regulation of keratinocyte growth and early differentiation, rather than terminal differentiat

177 isms of RA-induced Hoxa1 expression and ESCs early differentiation remain largely unknown.

178 Microarray analysis at various times during early differentiation reveal that mesoderm- and endoderm

179 ion, tubular organization and elongation and early differentiation) revealed signaling pathways poten

180 lterations in their generation, survival, or early differentiation, since all occurred normally in in

181 Upon early differentiation, SMAD2/3 signaling is decreased wh

182 ive ascending (inside-out) placement, common early differentiation stage (regardless of size, locatio

183 ells by delivering IL-1 signaling during the early differentiation stage and integrating IL-23 signal

184 study identifies IL-26-producing cells as an early differentiation stage of T(H)17 cells that infiltr

185 eukemic cell lines corresponding to the same early differentiation stages express abundant NELL2 mRNA

186 Early differentiation stages mainly displayed enhancer d

187 the transition from the proliferative to the early differentiation stages of myogenesis.

188 xpression is a general characteristic of the early differentiation stages of rodent trophoblast, give

189 ast, forced expression of polysialic acid in early differentiation stages reduces myotube formation a

190 ted cells exhibit phenotypes associated with early differentiation stages.

191 genesis, while Six genes appear to act in an early differentiation step during thymus/parathyroid mor

192 bx4 mutant mice result from a failure in the early differentiation step of chondroprogenitors into ch

193 if treated with patterning molecules at very early differentiation steps before neural induction.

194 During early differentiation steps, the ES cell factor Tbx3 ass

195 ation, while P2X5 and P2X7 receptors control early differentiation, terminal differentiation and deat

196 1 is required to maintain Oct4 expression at early differentiation time points.

197 two TLE genes expressed most dynamically in early differentiation, TLE3 and TLE4.

198 t progenitors intrathymically while delaying early differentiation until lineage restrictions have be

199 in each head segment, we have examined their early differentiation using Alcian labeling of cartilage

200 A remarkable general feature of early differentiation was a resolution of complexity thr

201 induction of scd1 expression by cAMP during early differentiation was distinct from that observed du

202 By measuring membrane tension during early differentiation, we find that naive stem cells rel

203 inhibition may be particularly important in early differentiation when large tracts of H3K9me2 are t

204 s suggest that TLE activity is essential for early differentiation where it acts to suppress the plur

205 regulated independent of pluripotency during early differentiation, which is distinct from what occur

206 myogenic regulatory proteins shifted toward early differentiation with increased erythropoietin rece

207 gulatory network to balance self-renewal and early differentiation within the "mitotic region," which

208 AT12 protein was found expressed in the root early differentiation zone, where its abundance was modu