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1 cious nuclear translocation of NRDE-3 in the early embryo.
2 rrors and thus approximately constant in the early embryo.
3 umber of primordial germ cells (PGCs) in the early embryo.
4 quired for cleavage furrow ingression in the early embryo.
5 regulating regions of open chromatin in the early embryo.
6 nstrates paternal-specific expression in the early embryo.
7 s for regulation of lineage decisions in the early embryo.
8 enuates pMad and Dpp signalling range in the early embryo.
9 le progression in the Caenorhabditis elegans early embryo.
10 ar characteristics of the totipotent egg and early embryo.
11 gans caudal homolog, to the posterior of the early embryo.
12 robust regulation in the quickly developing early embryo.
13 selecting target genes for activation in the early embryo.
14 its role in regulating BMP signaling in the early embryo.
15 increased efficiency of wound repair in the early embryo.
16 quiescent oocytes to dynamic exchange in the early embryo.
17 ively regulates aph-1(zu147) activity in the early embryo.
18 how that their differentiation starts in the early embryo.
19 cytial blastoderm nuclear cycle phase of the early embryo.
20 e in the primitive streak and tailbud of the early embryo.
21 curate automated cell tracking in the entire early embryo.
22 nced by micronutrient supplementation in the early embryo.
23 ies all cells with hematopoietic fate in the early embryo.
24 tro, reflecting developmental changes in the early embryo.
25 temporal regulation of their function in the early embryo.
26 shed by those same signaling pathways in the early embryo.
27 t arise from cartilaginous precursors in the early embryo.
28 tivities to generate sharp boundaries in the early embryo.
29 ating anterior endoderm transcription in the early embryo.
30 dynamic morphogenetic events that shape the early embryo.
31 nserved factors that induce asymmetry in the early embryo.
32 -RK family and is broadly transcribed in the early embryo.
33 o maintain DE-cadherin protein levels in the early embryo.
34 on the ventral-to-dorsal BMP gradient in the early embryo.
35 that regulates centrosome positioning in the early embryo.
36 limits the activity of both pathways in the early embryo.
37 s along the anteroposterior (AP) axis of the early embryo.
38 global heterochromatin establishment in the early embryo.
39 ome despite the rapid division cycles in the early embryo.
40 for TOST-1:PETISCO in SL1 homeostasis in the early embryo.
41 organization and cell cycle function of the early embryo.
42 s than 10% of the total ATPs produced in the early embryo.
43 e adult and alter correct development in the early embryo.
44 itioning cells to the inner cell mass of the early embryo.
45 igand, Trunk, are expressed uniformly in the early embryo.
46 expressed in early developing endosperm and early embryo.
47 those operating in primordial germ cells and early embryos.
48 rs in the yolk sac and immature microglia in early embryos.
49 inucleotides in the hypomethylated genome of early embryos.
50 the rga locus, which is highly expressed in early embryos.
51 lated at their 3' ends in mature oocytes and early embryos.
52 ring mitotic cycles in frog-egg extracts and early embryos.
53 attern similar to that in migratory PGCs and early embryos.
54 de cell polarization and axis orientation in early embryos.
55 l for two separate cell-cell interactions in early embryos.
56 he establishment of the pluripotent state in early embryos.
57 ity and defects in chromosome segregation in early embryos.
58 which is normally present at high levels in early embryos.
59 ome-wide DNA demethylation in germ cells and early embryos.
60 maintain genome stability in stem cells and early embryos.
61 anules are cytoplasmic bodies in oocytes and early embryos.
62 ly regulate multiple developmental events in early embryos.
63 ntral (DV) axes and midline determination in early embryos.
64 an capture up to 75% more genes expressed in early embryos.
65 taining grafts induces ectopic outgrowths in early embryos.
66 nogaster influence the mRNA transcriptome of early embryos.
67 ng during mitosis is also seen in C. elegans early embryos.
68 block in oocytes, but not by its removal in early embryos.
69 umu regulates ZGA partially through Zelda in early embryos.
70 genome and the environment in germ cells and early embryos.
71 al migration of the primordial germ cells in early embryos.
72 3, are also expressed throughout the soma of early embryos.
73 pment originates from lineage segregation in early embryos.
75 eviously in unstaged embryos, revealing that early embryos accumulate poised Pol II and that poising
76 nase inhibitor, normally undetectable in the early embryos, accumulates at high levels in the absence
77 (L1) retrotransposition has been detected in early embryos, adult brains, and the gastrointestinal (G
80 xtraembryonic tissues when reintroduced into early embryos, although the molecular mechanism underlyi
85 or inhibiting Xist and X-inactivation in the early embryo and in cultured stem cells of extra-embryon
86 ch Chk1 blocks cell-cycle progression in the early embryo and is an essential function of Chk1 at the
87 patiotemporal expression of ash genes in the early embryo and larval stages suggests that they regula
88 sion drive both global reorganization of the early embryo and local remodeling during organogenesis.
89 ly induces double-stranded DNA breaks in the early embryo and male germline, these breaks are not cor
91 capitulate the biophysical properties of the early embryo and mediate the self-organization of "gastr
92 served spatiotemporal dynamics of Cic in the early embryo and might explain RTK-dependent control of
93 inst full trisomy of some chromosomes in the early embryo and provides data for estimation of recurre
94 imary function of Delta40p53 in cells of the early embryo and stem cells, which are the only normal c
95 e-versus-outside positioning of cells in the early embryo and stochastic expression of key transcript
96 -type cyclin in cell cycle regulation in the early embryo and suggest that CYB-3 asymmetry helps esta
97 protein is present in all blastomeres of the early embryo and that its abundance oscillates with the
98 s required to form resistance alleles in the early embryo and that maternally-deposited Cas9 alone ca
99 aturally during mammalian development in the early embryo and the developing germ line, and artificia
101 stablished prior to gastrulation in the very early embryo and, because it is systemic, can be assesse
102 cy is a state that exists transiently in the early embryo and, remarkably, can be recapitulated in vi
103 es correlate with increased cell mobility in early embryos and abnormal craniofacial morphology in la
104 o accumulate stably at the cell periphery in early embryos and at the apical surface in pharyngeal an
107 ey differentially regulate the heart rate of early embryos and equally facilitate heart function in o
108 alyzed the planar cell divisions in ascidian early embryos and found that spindles in every cell tend
109 a gene that is expressed in the notochord of early embryos and in multiple epithelia during later dev
111 red gene expression of metabolic pathways in early embryos and islets of F1 offspring, which was unre
112 domain organization is remarkably similar in early embryos and L3 larvae, with conservation of 85% of
113 ive hAgo2 is required to elicit RNAi in both early embryos and oocytes using either siRNA or endogeno
114 t surrounds all mammalian oocytes, eggs, and early embryos and plays vital roles during oogenesis, fe
116 hat some of them are actively transcribed in early embryos and the proper regulation of retrotranspos
117 Here, we use chromatin state analyses in early embryos and third-larval stage (L3) animals to inv
118 domain protein Elba2, which is expressed in early embryos and was hypothesized to have insulator-spe
119 iched in nuclear extracts from late, but not early, embryos and that it contains three insulator prot
120 ons that are transcribed in the germline and early embryo, and ectopic transcription of genes in a mu
122 terization of starch turnover during flower, early embryo, and silique development in Arabidopsis (Ar
123 programming occurs in primordial germ cells, early embryos, and embryonic stem cells where reciprocal
125 ammalian primordial germ cells (PGCs) and in early embryos, and is important for the erasure of impri
126 -specific DNA methylomes from mouse gametes, early embryos, and primordial germ cell (PGC), as well a
127 lationally repressed properly in oocytes and early embryos, and then correctly translated only in the
129 The commitment to the cell cycle in the early embryo appears to preclude many other cellular pro
133 which are resistant to demethylation in the early embryo, are resistant to vitamin-C-induced DNA dem
134 nse, increased recombination-based repair in early embryos as determined by plasmid-based reporters.
135 and regulation of protein trafficking in the early embryo, as well as serve as a tool for manipulatin
136 critical features of the methylome of human early embryos, as well as its functional relation to the
137 echnology (ART) involves the manipulation of early embryos at a time when they may be particularly vu
138 he proper zygotic genome activation (ZGA) in early embryos, at least in part, by regulating zelda exp
139 K genes causes an analogous phenotype in the early embryo before the onset of hematopoietic stem/prog
140 re more numerous, more widely distributed in early embryos before colonization into the gonads, had s
141 ints on splicing were likely to exist in the early embryo, being splicing avoidance a possible explan
142 island promoters--that are maintained in the early embryo but are lost upon specification and absent
143 as loss of end-3 halves ELT-2 levels in the early embryo but levels fully recover by the time of hat
144 t of polarity axes in the developing egg and early embryo, but has no known somatic functions or expr
145 t plays essential roles in mouse oocytes and early embryos, but the functional role of individual ami
146 initiate zygotic transcription in Drosophila early embryos, but whether other factors support this dy
147 Mitotic spindles specify cleavage planes in early embryos by communicating their position and orient
148 that we have previously shown to be bound in early embryos by the maternally deposited transcription
149 tones in later development, may be shared in early embryos by weakly homologous proteins, such as Big
150 ate decisions because of the ease with which early embryos can be recovered and the availability of a
151 Furthermore, overexpression of Mtrm in the early embryo caused aberrant nuclear divisions and devel
156 igh levels of many of these rab genes in the early embryo, chemical inhibitors of Rab functions rescu
157 three-dimensional computational model of the early embryo, consisting of pseudoelastic plates represe
158 loss of all six TIR1/AFB proteins results in early embryo defects and eventually seed abortion, and y
160 indicates that TEs are highly transcribed in early embryo development and contribute to distinct biol
162 d in active demethylation of H3K27me3 during early embryo development and that this mark plays an imp
166 nstrate that AtBUD13 plays critical roles in early embryo development by effecting pre-mRNA splicing.
168 he mitochondrial matrix and is essential for early embryo development in Arabidopsis (Arabidopsis tha
170 tives on DNA methylation heritability during early embryo development that extend beyond conventional
171 embles some aspects of egg fertilization and early embryo development that lead to transcriptional ac
172 data reveal a novel function of PADI1 during early embryo development transitions by catalyzing histo
175 at both calcium regulators are essential for early embryo development, and that knockdown of PmTPCs l
176 domains and grouped them into three groups (early embryo development, late embryo development, and e
177 rkable effects on both oocyte maturation and early embryo development, which in turn can have lifelon
189 in mammalian development is how cells of the early embryo differentiate into distinct cell types.
190 pose that, unlike more cohesive tissues, the early embryo dissipates tensile forces required by const
191 contribution of SSP to YDA activation in the early embryo does not overlap with the contributions of
192 We show that, in Xenopus laevis oocytes and early embryos, double-stranded exogenous siRNAs cannot f
193 characteristic of specific cells within the early embryo (e.g., epiblast cells) and of certain cells
194 length TET1 isoform (TET1e) is restricted to early embryos, embryonic stem cells (ESCs), and primordi
195 may be particularly relevant in oocytes and early embryos enlarged for developmental competence, cel
196 om neoblasts: they express unique cohorts of early embryo enriched transcripts and behave differently
198 ived DNA methylation escapes reprograming in early embryos, epigenetic defects in sperm may be transm
199 question in developmental biology is how the early embryo establishes the spatial coordinate system t
201 activation of cre/lox based gene excision in early embryo extraembronic trophoblast tissues as well.
204 ought that the bilateral heart fields in the early embryo fold directly towards the midline, where th
206 ematopoietic cells in the mouse arise in the early embryo from Brachyury-positive multipotent cells i
207 ystematically profile the methylome of human early embryos from the zygotic stage through to post-imp
212 or anterior-posterior (AP) patterning in the early embryo, have uncovered two distinct ways of scalin
214 a window(s) of opportunity in the zygote and early embryo; (ii) there is no statistical variation of
215 lizes asymmetrically to the posterior of the early embryo in a PKC-3-dependent manner, and functions
216 n to be necessary for the development of the early embryo in mammals, but the molecular processes aff
217 However, whole-transcriptome analysis of early embryos in flowering plants has been hampered by t
219 cing of a small number of transcripts in the early embryo, including the pre-mRNA that encodes the ap
222 actomyosin structures during wound repair in early embryos involves disassembly of the actomyosin net
224 ration of cells in the mesoderm layer of the early embryo is essential for organization of the body p
228 ablishing X chromosome inactivation (XCI) in early embryos, is conditionally deleted from Xi in somat
234 ssues, and Cubn gene inactivation results in early embryo lethality most likely due to the impairment
238 to early embryogenesis, we characterized the early embryo Me31B interactome and compared it to the kn
241 ession to read the sex chromosome karyotype, early embryos must remain gender-naive; our findings sho
243 Although we apply our DNNto data from the early embryo of the fruit fly Drosophila, this system se
248 Recent single cell RNA-sequencing studies of early embryos or in vitro-differentiated human embryonic
249 otent stem cells are derived from culture of early embryos or the germline and can be induced by repr
250 sential for establishment and maintenance of early embryo polarity and their homologs in other organi
251 rked by an initial auxin maximum, suggesting early embryo proper establishment in the absence of a ba
253 ize that these cells of the Veg2 tier of the early embryo represent a lineage that converts to the ge
255 Exponential increase of cell numbers in early embryos requires large amounts of DNA precursors (
256 e have previously shown that the oocyte- and early embryo-restricted maternal effect gene Mater (Nlrp
259 ression templates from a cohort of zebrafish early embryos spanning 6 developmental stages from 4 to
260 down-regulation of Cdx2 transcripts from the early embryo stage results in defects in TE specificatio
261 BPs are enriched in posterior regions of the early embryo, suggesting their general importance in pos
262 in-bound levels of PCNA in both S2 cells and early embryos, suggesting that the Enok complex may inte
263 influence of symbiont on mRNA composition of early embryos, suggesting that the reproductive manipula
264 of genes that are normally not expressed in early embryos, suggesting that Zld controls the genome-w
265 er abundance of transcripts, indicating that early embryos tend to retain higher residual methylation
266 polarity defects are more apparent in par-2 early embryos than in par-1 or par-4, except for strd-1(
267 sun is much higher in Drosophila ovaries and early embryos than in testes, we herein sought to determ
269 mergent short naive pluripotent signature in early embryos, there is a protracted appearance of a pri
270 maternal origin are distributed uniformly in early embryos, this pattern changes as development proce
271 ecific genes in germline function and in the early embryo, through overexpression or RNA interference
273 that the mir-35 family microRNAs act in the early embryo to function as a developmental timer that p
275 e of the natural adherence properties of the early embryo to position them in a single layer on a pol
278 ng the responses of pluripotent cells in the early embryo to the signals that regulate germ layer spe
279 sperm RNA-encoded information is decoded in early embryos to control offspring phenotypes also remai
280 LICs in human cell lines and Xenopus laevis early embryos to dissect the LICs' role in cell division
283 ssues, from the separation of tissues in the early embryo, to turnover in the homeostasis of the gast
284 published Arabidopsis thaliana endosperm and early embryo transcriptomes generated in these studies.
286 tion of a prototypic 4D atlas for vertebrate early embryos, using multicolor fluorescence in situ hyb
287 he donor cell (before reconstruction) or the early embryo was exposed to the probe to assess its effe
288 te the processes that generate forces within early embryos, we developed a novel gel-based sensor to
289 ncing of small RNAs from Bactrocera dorsalis early embryos, we identified an autosomal-derived microR
290 solution maps of oxidized cytosine bases for early embryos, we report the existence of 5hmC and 5fC i
291 uring transcript levels in single cells from early embryos, we show that CHD4 influences the frequenc
293 The process starts in the endoderm of the early embryo where precursors of endocrine cells and ent
294 for heterochromatin assembly, likely in the early embryo, where piRNA pathway components are abundan
295 We find that wound closure is faster in early embryos, where, in addition to a purse string arou
296 high threshold target gene expression in the early embryo, while expression of a Mad linker mutant in
297 ylation dynamics in mammalian germ lines and early embryos with a focus on both mice and humans.
298 confocal microscopy and explants cultures of early embryos with ERK-specific inhibitors suggest an im
300 ults in the dissolution of P granules in the early embryo, with an apparent submicromolar phase bound