ライフサイエンスコーパス: early goal-directed therapy

1 al 5998 patients (3042 before and 2956 after early goal-directed therapy).

2 pulations of critically ill patients, and on early goal-directed therapy.

3 Studies that evaluated early goal-directed therapy.

4 Early goal-directed therapy.

5 with an early resuscitation protocol such as early goal-directed therapy.

6 severe sepsis and septic shock treated with early goal-directed therapy.

7 tion, severity of illness, and initiation of early goal-directed therapy.

8 rgest roadblocks to overcome in implementing early goal-directed therapy.

9 onths (EuroQoL-5D-3L utility scores at 12 mo early goal-directed therapy 0.65 +/- 0.33 vs usual care

10 mortality between groups at either 6 months (early goal-directed therapy 21.8% vs usual care 22.6%; p

11 vs usual care 22.6%; p = 0.70) or 12 months (early goal-directed therapy 26.4% vs usual care 27.9%; p

12 lled patients, 130 were randomly assigned to early goal-directed therapy and 133 to standard therapy;

13 ssociated with mortality differences between early goal-directed therapy and control included Acute P

14 ions such as 24-hr intensivist availability, early goal-directed therapy, and renal replacement thera

15 ppropriate antibiotic co-intervention in the early goal-directed therapy arm compared with controls i

16 ssess the cost-effectiveness of implementing early goal-directed therapy as a routine protocol.

17 1 yr before; and 2) 2 yrs after implementing early goal-directed therapy as standard of care.

18 ty was 30.5 percent in the group assigned to early goal-directed therapy, as compared with 46.5 perce

19 ectrum antibiotics within 4 hrs; c) complete early goal-directed therapy at 6 hrs; d) give corticoste

20 f this study was to evaluate the efficacy of early goal-directed therapy before admission to the inte

21 dance was not associated with differences in early goal-directed therapy bundle compliance or hemodyn

22 g the phenotype frequencies within an RCT of early goal-directed therapy changed the results from >33

23 mergency department with early septic shock, early goal-directed therapy compared with usual care did

24 s prompt recognition and aggressive therapy; early goal-directed therapy decreases morbidity and mort

25 pathway incorporating empirical antibiotics, early goal-directed therapy, drotrecogin alfa, steroids,

26 Early goal-directed therapy (EGDT) has been endorsed in

27 Early goal-directed therapy (EGDT) reduced mortality fro

28 characteristics and individual components of early goal-directed therapy (EGDT) to determine treatmen

29 re treated according to a 6-hour protocol of early goal-directed therapy (EGDT), in which intravenous

30 Early, goal-directed therapy (EGDT) is recommended in in

31 al and observational studies suggesting that early, goal-directed therapy (EGDT) reduced mortality fr

32 enotype comparing usual care to protocolized early, goal-directed therapy(EGDT).

33 Early goal-directed therapy for severe sepsis and septic

34 to implementation of a written protocol for early goal-directed therapy for severe sepsis in the bus

35 In particular, the rise of early goal-directed therapy for the initial resuscitatio

36 from 7 to 72 hours, the patients assigned to early goal-directed therapy had a significantly higher m

37 Early goal-directed therapy has been externally validate

38 Early goal-directed therapy has shown discordant surviva

39 Implementation of early goal-directed therapy in the emergency department

40 omized trial showed decreased mortality with early, goal-directed therapy in septic shock, a strategy

41 rotocol incorporating empirical antibiotics, early goal-directed therapy, intensive insulin therapy,

42 indicates a 98% probability (p = .038) that early goal-directed therapy is cost-effective at a willi

43 The emerging new literature on early goal-directed therapy is most applicable to care i

44 The use of early goal-directed therapy might be important in minimi

45 Early goal-directed therapy modulates systemic inflammat

46 septic shock to receive either six hours of early goal-directed therapy or standard therapy (as a co

47 Early goal-directed therapy provides significant benefit

48 likely to endorse lack of agreement with the early goal-directed therapy resuscitation protocol (16%

49 abstracts (4429 patients) after the original early goal-directed therapy study were identified from a

50 gan dysfunction, in the patients assigned to early goal-directed therapy than in those assigned to st

51 izations developed management guidelines for early goal-directed therapy that would be of practical u

52 psed times from triage and qualification for early goal-directed therapy to administration of appropr

53 antibiotic administration, qualification for early goal-directed therapy to antibiotic administration

54 e from triage or time from qualification for early goal-directed therapy to antibiotics and mortality

55 biotic administration, and qualification for early goal-directed therapy to appropriate antibiotic ad

56 ; similarly, for time from qualification for early goal-directed therapy to appropriate antibiotics,

57 These findings are superior to the original early goal-directed therapy trial which showed figures o

58 Early goal-directed therapy use was associated with a co

59 Early goal-directed therapy versus usual care.

60 The analysis from 37 studies showed that early goal-directed therapy was associated with a 23% re

61 Treatment with early goal-directed therapy was associated with an incre

62 Early goal-directed therapy was associated with increase

63 g the five quality indicators, completion of early goal-directed therapy was significantly associated