ライフサイエンスコーパス: early intervention

1 cations for designing rational approaches to early intervention.

2 stage disease, offering the opportunity for early intervention.

3 tanding PsAF, underscoring the importance of early intervention.

4 control based on therapeutic monitoring and early intervention.

5 achexia in cancer patients are necessary for early intervention.

6 but also providing potential strategies for early intervention.

7 may be useful for identifying candidates for early intervention.

8 ritical step toward advancing prevention and early intervention.

9 viduals at highest risk who may benefit from early intervention.

10 t may precede systemic infection and require early intervention.

11 fy high-risk women who should be targets for early intervention.

12 identify a high-risk subset of survivors for early intervention.

13 g brain markers might assist in referral for early intervention.

14 on for informing treatment approaches during early intervention.

15 mer's disease is important for prognosis and early intervention.

16 on and could benefit from clinical trials of early intervention.

17 h AVD by promoting personalized medicine and early intervention.

18 s cause long-term morbidity but benefit from early intervention.

19 mental, and early detection is essential for early intervention.

20 t redox modulation as a potential target for early intervention.

21 oups and geographic location for focused and early intervention.

22 the overall health of the infant assists in early intervention.

23 s that can further reduce infarct size after early intervention.

24 logical levels could have great benefits for early intervention.

25 used public health target for prevention and early intervention.

26 y progress to invasiveness in the absence of early intervention.

27 tal social interaction, providing a route to early intervention.

28 ant insight into the etiology of obesity and early intervention.

29 benefit from aggressive supportive care and early intervention.

30 m public health strategies on prevention and early intervention.

31 related risk factors, providing a target for early intervention.

32 and low rates are important to pinpoint for early intervention.

33 equire closer observation and more intensive early intervention.

34 ho may need closer follow-up or benefit from early intervention.

35 S patients, including biomarkers/targets for early intervention.

36 mplicated TBAD patients who may benefit from early intervention.

37 ing participants in clinical trials aimed at early intervention.

38 n trigger MG in some patients, necessitating early intervention.

39 ight in identifying effective strategies for early intervention.

40 d to detect behavioural changes relevant for early intervention.

41 ibody detection might lead to less invasive, early interventions.

42 in recent trauma survivors is important for early interventions.

43 both as a marker of risk and as a target for early interventions.

44 s others may insist on intense follow-up and early interventions.

45 h should look at this interplay for possible early interventions.

46 in an independent testing set, facilitating early interventions.

47 dict risk and aid in stratification to guide early interventions.

48 high-risk signs of progression, and to study early interventions.

49 litate early diagnosis and access to crucial early interventions.

50 disease have nurtured the emergent need for early interventions.

51 may inform the construction of more targeted early interventions.

52 risk for later major depression and applying early interventions.

53 geted for in depth diagnostic procedures and early interventions.

54 ty disorder, as it may have implications for early interventions.

55 tion of peanut allergy (PNA) is relevant for early interventions.

56 nhibitor (GS-444217 delivered in chow) as an early intervention (2-8 weeks after STZ) or late interve

57 avioral impairment, were examined under both early intervention (7-month-old young-adult male mice wi

58 ification-tree algorithm to guide studies of early intervention after CAR T-cell infusion for patient

59 risk for ASD who might benefit from targeted early interventions aimed at preventing or ameliorating

60 festations, namely IBD-related arthritis, an early intervention allows to control disease activity an

61 Early intervention among those involved in bullying can

62 rguments in favor of NBS include benefits of early intervention and follow-up for the identified baby

63 Research must inform the benefits of early intervention and implementation of policies to add

64 echanistically related biomarkers needed for early intervention and MMP9/RAGE pathway modulation may

65 ead to new insight for developing biomarker, early intervention and novel therapeutics.

66 discussing opportunities for prevention and early intervention and outlining challenges in the asses

67 sceptibility is warranted to inform targeted early intervention and prevention efforts.

68 Early intervention and prevention of psychosis remain a

69 ic impairment is the most effective route to early intervention and prevention or postponement of age

70 nd early detection of SARS-CoV-2 facilitates early intervention and prevents the disease spread.

71 a complete response, prompting us to propose early intervention and search for additional targetable

72 lculator represents a meaningful step toward early intervention and the personalized treatment of psy

73 Early intervention and tight control of inflammation opt

74 s desirable, the evidence of the benefits of early intervention and treatment for older hospitalised

75 ight be incorporated into newborn screening, early intervention and, perhaps, carrier testing and pre

76 gh risk of AD would be important in planning early intervention and/or prevention studies.

77 of natural disasters should be targeted with early interventions and active long-term follow-up to pr

78 ternalizing subtypes may assist in targeting early interventions and assessing longitudinal prognosis

79 The effects of early interventions and longer term implications of thes

80 n of those parents at high risk and for more early interventions and prevention research, especially

81 who may benefit the most from prevention and early intervention, and ascertain modifiable protective

82 nisms, improve strategies for prevention and early intervention, and better target our treatments thr

83 ic condition offers a unique opportunity for early intervention, and monitoring individuals with 22q1

84 vel strategies for the diagnosis, treatment, early intervention, and prevention of schizophrenia.

85 Surveillance, early interventions, and cHL treatment refinements may f

86 As adolescent obesity tracks into adulthood, early interventions are needed to prevent progression to

87 Proponents of early intervention argue that the complications of CLM,

88 The early intervention arm subjects detected exacerbations m

89 The early intervention arm subjects measured home spirometry

90 rently not amenable to primary prevention or early intervention because their natural history cannot

91 that our solution allows early detection and early intervention before a patient's condition starts d

92 early biomarkers and new targets to promote early intervention beginning in school age.

93 ovide patients and carers with the chance of early intervention, better disease management, and effic

94 high risk for schizophrenia may benefit from early intervention, but few validated risk predictors ar

95 cognitive deficits late in life, suggesting early intervention by enhancing GABA signaling as a pote

96 en who are at high risk for deficits so that early intervention can be initiated to mitigate the impa

97 It is not known whether early intervention can improve long-term autism symptom

98 anding question concerns the extent to which early intervention can normalize trajectories of brain d

99 Whether early intervention can prevent development of ARDS remai

100 ction of certain medical conditions in which early intervention can prevent serious, life-threatening

101 Participants were recruited from early intervention centers.

102 res are needed for diagnostic monitoring and early intervention clinical trials.

103 ical monitoring, risk factor evaluation, and early intervention could benefit women with hypertension

104 sk family members for clinical screening and early intervention could reduce morbidity and mortality.

105 ill discover biomarkers that may help in the early intervention, diagnosis or treatment of SZ.

106 Although early intervention doubled the numbers of subjects dosed

107 Furthermore, early intervention downregulated several microglial rece

108 is, supporting their potential utility as an early intervention during pulmonary infections.

109 may be a potential target for prevention and early intervention efforts aimed at reducing the occurre

110 phenomenon, and underscore the importance of early intervention efforts in this disabling neuropsychi

111 ng patients who receive TBI may benefit from early intervention efforts to minimize cognitive losses

112 s association is often cited when justifying early intervention efforts, it is imperative to better u

113 omising public health strategy for providing early intervention for a variety of child mental health

114 Focused early intervention for communication during mechanical v

115 nt paradigms, with the possible inclusion of early intervention for contracture avoidance and assista

116 nts experiencing CAR T-cell toxicities, with early intervention for hypotension and treatment of conc

117 Early intervention for neglect or emotional abuse in pre

118 ive biomarker to enable close monitoring and early intervention for patients receiving ipilimumab.

119 Early intervention for substance use is critical to impr

120 guage, the results point to the necessity of early intervention for the individuals with autism who s

121 individuals with SCA is warranted, enabling early intervention for those at risk.

122 Early interventions for at-risk ICU survivors may improv

123 These findings highlight the need for early interventions for dementia prevention to mitigate

124 nce of identifying underlying mechanisms and early interventions for diabetic cardiomyopathy.

125 Early interventions for prevention of T2DM and prescribi

126 Prevention of and early interventions for psychiatric illness and treatmen

127 the development of mechanistically informed early interventions for psychosis.

128 distinguish patients who would benefit from early intervention from those who may be reliably observ

129 antisocial personality were improved in the early intervention group at long-term follow-up compared

130 The early intervention group received early cuff deflation a

131 evidence on the effectiveness of prevention, early intervention, harm reduction, and treatment of pro

132 Although early intervention has been shown to support more normat

133 Family-centered early intervention has the potential to prevent problems

134 Although early interventions have been used for the treatment of

135 We present evidence supporting early intervention immediately following a positive diag

136 This is disconcerting because early intervention improves outcomes and deterioration i

137 Early intervention improves prognosis in autism spectrum

138 Early intervention in Alzheimer's Disease (AD) requires

139 practices for a genetics-driven approach to early intervention in at-risk relatives.

140 ction after a randomised controlled trial of early intervention in autism spectrum disorder.

141 To evaluate the effects of early intervention in calcium homeostasis, we used 2 mou

142 First is a re-examination of strategies for early intervention in critical aortic stenosis.

143 dren aged 3-6 years, and could be a suitable early intervention in cystic fibrosis.

144 d the potential importance of prevention and early intervention in high-risk populations.

145 An optimal therapeutic candidate for early intervention in ischemic stroke should be effectiv

146 Early intervention in offspring of 2 generations affecte

147 study provides evidence for the efficacy of early intervention in preventing adult psychopathology a

148 erging data pointing to the effectiveness of early intervention in remediating neurodevelopmental con

149 Early intervention in select patients may lead to potent

150 and functional remodelling, suggesting that early intervention in the insulin-adrenergic signalling

151 ment and represent new treatment targets for early intervention in these individuals.

152 e neural targets to better guide and monitor early interventions in bipolar disorder at-risk youth.

153 The limitations and caveats of early interventions in psychiatric disorders are also di

154 putative molecular and neuronal targets for early interventions in youth at CHR.

155 e adopted in practice to guide postdischarge early interventions, including the integrated provision

156 early detection, creating the illusion that early intervention is associated with improved outcomes.

157 Early intervention is crucial for the prevention of diab

158 Early intervention is necessary to minimize morbidities

159 Early intervention is needed to reduce the risk of endom

160 ediction of impending septic shock, and thus early intervention, is possible many hours in advance.

161 Early intervention likely prevented morbidity and possib

162 into AFL-induced remodeling and suggest that early intervention may be important to prevent irreversi

163 Early intervention may be key to safe and effective ther

164 Furthermore, early intervention may prevent long-term deficits in mem

165 l of disease reversibility and suggests that early intervention might be beneficial for FXTAS patient

166 Early intervention might improve long-term outcomes for

167 Close monitoring and early intervention might reduce the risk of hypomanic or

168 the need for effective regular screening and early intervention modalities to prevent the presence an

169 evention of these mental health problems and early intervention must be a priority.

170 ratios could be used for identification and early intervention of at-risk obese individuals.

171 No effects of the early intervention on dietary behaviors, quality of life

172 There was an indirect effect of early intervention on middle childhood psychosocial func

173 e studies are warranted to determine whether early intervention or closer monitoring improves clinica

174 y heart disease, all of which have available early intervention or prevention treatments.

175 , low-birthweight infants were randomized to early (intervention) or delayed (usual policy) BCG.

176 d unresponsiveness at 4 weeks after stopping early intervention oral immunotherapy (4-SU), was assess

177 and health service provision to incentivise early intervention over provision of care only for advan

178 Building on long-term benefits of early intervention (Paper 2 of this Series) and increasi

179 elop complications, our results suggest that early intervention, preferably in a high-level intensive

180 m might offer a sought-after opportunity for early intervention, preservation of cognitive reserve, a

181 Early intervention prior to subepithelial fibrosis can l

182 Early intervention programs for drug and alcohol misuse

183 These new findings suggest that early intervention programs should target children with

184 luded an autism clinic and 6 community-based early intervention programs that primarily serve low-inc

185 e individualized sessions by existing staff (early intervention programs) or research staff without f

186 form development of effective preventive and early intervention programs.

187 We used follow-up data from the Bucharest Early Intervention Project (BEIP), a randomised controll

188 We present results from the Bucharest Early Intervention Project examining whether randomized

189 The Bucharest Early Intervention Project is a randomized clinical tria

190 Data were drawn from the Bucharest Early Intervention Project, a cohort of children raised

191 om childhood to adolescence in the Bucharest Early Intervention Project, a randomized controlled tria

192 Follow-up analyses revealed that early intervention promoted more normative white matter

193 chosis cases, 16-35 years old, presenting to early intervention psychosis services in the East of Eng

194 chosis cases, 16-35 years old, presenting to early intervention psychosis services in the East of Eng

195 or urban settings since the introduction of early intervention psychosis services.

196 0 years old, exists in populations served by early intervention psychosis services.

197 ification of infants at risk and could guide early intervention regimens.

198 Hence, although early interventions remain critical, interventions to im

199 at high risk of developing psychosis to the early intervention service per practice site.

200 ants to receive social recovery therapy plus early intervention services (n=76) or early intervention

201 y plus early intervention services (n=76) or early intervention services alone (n=79); the intention-

202 therapy plus early intervention services or early intervention services alone.

203 h (95% CI 2.5-13.6; p=0.0050) compared with early intervention services alone.

204 We aimed to assess the efficacy of early intervention services augmented with social recove

205 Violent behavior at 6 or 12 months following early intervention services entry.

206 non-affective psychosis, had been clients of early intervention services for 12-30 months, and had pe

207 Provision of early intervention services has increased the rate of so

208 This study included 6 early intervention services in 5 geographical locations

209 rolled trial (SUPEREDEN3) at four specialist early intervention services in the UK.

210 EN (Evaluating the Development and Impact of Early Intervention Services in the West Midlands) Study

211 ix), to receive social recovery therapy plus early intervention services or early intervention servic

212 Social recovery therapy plus early intervention services was associated with an incre

213 thesis was that social recovery therapy plus early intervention services would lead to improvements i

214 23 (26.7%) received first-time referrals for early intervention services, 16 (13.8%) received referra

215 is who received social recovery therapy plus early intervention services.

216 Early intervention significantly hastened return to phon

217 However, early intervention significantly reduces the incidence o

218 Precise and early intervention strategies are urgently needed.

219 In summary, early intervention strategies can be based robustly just

220 These findings might help to guide early intervention strategies for at-risk youths.

221 These findings are important for designing early intervention strategies for secondary prevention o

222 ified serum biomarkers that allow testing of early intervention strategies in patients at the highest

223 midlife, a critical window for implementing early intervention strategies to reduce CVD risk.

224 the utility of addressing these symptoms in early intervention strategies.

225 sis, expanding the repertoire of targets for early intervention strategies.

226 Targeting self-regulation may present an early intervention strategy for children facing genetic

227 These data provide a framework for early intervention studies to facilitate safer applicati

228 Early intervention studies to repair the epidermal barri

229 Our results suggest that rapid early interventions successfully prevented early introdu

230 omycin-injury IPF model, we demonstrate that early-intervention suicide-gene-mediated senescent cell

231 trate that, contrary to current thinking, an early intervention targeting NOD-like receptor family, p

232 and will help identify cancer prevention and early intervention targets.

233 lable evidence about cerebral palsy-specific early intervention that should follow early diagnosis to

234 These findings highlight the need for early interventions that can improve treatment outcomes

235 ntification may in turn facilitate access to early interventions that could prevent a life spent stru

236 Offering hope, early interventions that place institutionalised childre

237 Moreover, early intervention therapy did not increase the proporti

238 Therefore, these findings support early intervention therapy for individuals with T1D.

239 These findings suggest that early intervention to change these modifiable risk facto

240 stive health of individual animals, allowing early intervention to effectively adjust feeding strateg

241 lity changes could afford an opportunity for early intervention to forestall tissue damage in newly f

242 al targets across multiple organ systems for early intervention to improve cardiometabolic health.

243 Early intervention to interrupt transmission may be most

244 hese known social risk factors and providing early intervention to negate long-term sequelae.

245 ce of prompt referral to diagnostic-specific early intervention to optimize infant motor and cognitiv

246 ized controlled trial tested the efficacy of early intervention to prevent adult psychopathology and

247 An ideal multifactorial and early intervention to prevent cancer cachexia could take

248 m cell transplantation in FA and NBS, future early intervention to prevent complications of disease w

249 rapy, suggesting that careful monitoring and early intervention to prevent glaucoma is warranted with

250 s an integrated approach, which includes the early intervention to prevent or delay the disease progr

251 ctor for MCI and may provide a substrate for early intervention to prevent or delay the onset and pro

252 flammatory response underscores the need for early intervention to prevent perioperative tissue injur

253 ecurrent pneumothorax who would benefit from early intervention to prevent recurrence.

254 ression in children could be used to promote early intervention to reduce the likelihood of developin

255 Early intervention to restore pressure natriuresis in T1

256 ents with cirrhosis should be prevention and early intervention to stabilise disease progression and

257 provided little support for the idea that an early intervention to support household income has a lar

258 on of these gene variations is important for early intervention to treat deadly diseases and provide

259 erm neurodevelopmental deficits and targeted early interventions to improve clinical outcomes in very

260 rther study is required to determine whether early interventions to optimize LVSWI can improve outcom

261 to support the use of routine screening and early interventions to prevent and treat suicidal ideati

262 ased screening approaches that might lead to early interventions to prevent LOS in high risk infants.

263 th or without MCI is a promising approach in early interventions to prevent or slow progression to de

264 hout known CVD highlights an opportunity for early interventions to prevent progression of cardiovasc

265 aging, and they suggest the possibility that early interventions to promote certain health behaviors

266 est prevention of AD can be achieved through early interventions to protect the skin barrier.

267 involvement of fathers as well as mothers in early interventions to reduce the prevalence of adolesce

268 tter allocation of resources and potentially early interventions to reduce unplanned visits.

269 Early interventions to tackle parental mental disorders

270 BB:zeta CAR targeting CD19 who also recieved early intervention treatment.

271 ts enrolled in the Acute Catheterization and Early Intervention Triage Strategy (ACUITY) trial, 1772

272 monitoring and as quantitative endpoints in early intervention trials in children with CF.

273 In high-risk children, early intervention using different hydrolyzed formulas h

274 contrast, in the selective high-risk sample, early intervention was not associated with improved long

275 Early intervention with a combination therapy of vildagl

276 ings support the rationale for investigating early intervention with a KMO inhibitor, with the aim of

277 er recovered, highlighting the importance of early intervention with A1PI treatment.

278 Comprehensive, naturalistic early intervention with active caregiver involvement can

279 ss than 65 years old, treated in a hospital, early intervention with an ID physician was associated w

280 In patients with acute heart failure, early intervention with an intravenous vasodilator has b

281 of adequate treatment, timely diagnosis and early intervention with antifungal drugs are key factors

282 chronization Therapy (MADIT-CRT) showed that early intervention with cardiac-resynchronization therap

283 In addition, early intervention with cholinergic receptor muscarinic

284 We conclude that early intervention with CoQ in at-risk individuals may b

285 r dysfunction, and left bundle-branch block, early intervention with CRT-D was associated with a sign

286 Early intervention with GS-444217 significantly inhibite

287 Early intervention with intravitreal anti-VEGF medicatio

288 We hypothesized that early intervention with lenalidomide could delay progres

289 Early intervention with lenalidomide in smoldering multi

290 Efficacy findings also suggest that early intervention with lumacaftor and ivacaftor has the

291 s at risk for Parkinson's disease and permit early intervention with neuroprotective or disease-modif

292 disease who are most likely to benefit from early intervention with novel treatments.

293 An early intervention with PNS and/or pharmaceutical inhibi

294 ng of psychoeducation (i.e., recognition and early intervention with prodromal symptoms), communicati

295 In contrast, early intervention with selective high-risk samples may

296 Early intervention with severely antisocial children for

297 While early intervention with these gold standard treatments i

298 We report that early intervention with tocilizumab and/or corticosteroi

299 These data support the contention that early intervention with tocilizumab and/or corticosteroi

300 antagonism is ineffective, and thus (3) that early intervention with TRP channel antagonists may atte