ライフサイエンスコーパス: early promoter

1 intron under control of the simian virus 40 early promoter.

2 roteins to transactivate the major immediate-early promoter.

3 ntrol of the human cytomegalovirus immediate-early promoter.

4 eins under a human cytomegalovirus immediate-early promoter.

5 vector bearing the cytomegalovirus immediate-early promoter.

6 virus vector under the cytomegalovirus major early promoter.

7 FP) from the human cytomegalovirus immediate early promoter.

8 eam U3 was replaced with the cytomegalovirus early promoter.

9 trol of the simian cytomegalovirus immediate early promoter.

10 ntrol of the cytomegalovirus major immediate-early promoter.

11 riven by the human cytomegalovirus immediate-early promoter.

12 the control of the cytomegalovirus immediate-early promoter.

13 binding to multiple sites in the Sex-lethal early promoter.

14 tic effect on the transcription of the viral early promoter.

15 virus LTR or human cytomegalovirus immediate early promoter.

16 nal control of the cytomegalovirus immediate early promoter.

17 g RNAs initiated at a region upstream of the early promoter.

18 ntrol of the cytomegalovirus (CMV) immediate-early promoter.

19 a reporter carrying the irs1/trs1 immediate-early promoter.

20 d under the control of cytomegalovirus (CMV) early promoter.

21 (Ad.betaGal), each driven by cytomegalovirus early promoter.

22 mutant Vp1 is expressed from simian virus 40 early promoter.

23 erted firefly luciferase, controlled by SV40 early promoter.

24 ression vector driven by the cytomegalovirus early promoter.

25 synthesis by binding to the major immediate-early promoter.

26 ion from an exogenous template containing an early promoter.

27 e the BoHV-1 infected cell protein 0 (bICP0) early promoter.

28 oter and the infected cell protein 0 (bICP0) early promoter.

29 ficient for IE86-mediated activation of this early promoter.

30 transcription from the viral major immediate-early promoter.

31 of an insulator at the intervening ladybird early promoter.

32 on of pUL29/28 activated the major immediate-early promoter.

33 earing human cytomegalovirus major immediate-early promoter.

34 al or cellular genes driven by CMV immediate-early promoter.

35 in under the human cytomegalovirus immediate-early promoter.

36 fective in repression of the major immediate-early promoter.

37 cing the oriLyt(PM) with the simian virus 40 early promoter.

38 ice with ORF74 driven by the simian virus 40 early promoter.

39 y late promoters but was not active on viral early promoters.

40 in under the control of endogenous immediate early promoters.

41 Ad5 E1A CR1 in the transactivation of viral early promoters.

42 ge promoters in vitro but does not recognize early promoters.

43 its ability to transactivate critical viral early promoters.

44 n reduced binding of Sp1, TBP, and Pol II to early promoters.

45 demethylase-1 (LSD1) to the viral immediate early promoters.

46 tion factor SP1 for transactivation of viral early promoters.

47 onstructs under the control of the immediate-early promoter (3.9-fold), the early thymidine kinase pr

48 transactivated an endogenous simian virus 40 early promoter 4 h earlier and to higher levels than the

49 rated with the PR to transactivate the bICP0 early promoter, a promoter that maintains bICP0 protein

50 IE2 86 implicated in the activation of HCMV early promoters, a predicted zinc finger domain, and a p

51 Decreasing transcription from early promoter A3 is sufficient to make gp2 dispensable

52 of a potent cytomegalovirus (CMV) immediate/early promoter (AAV-MD-rGDNF) was constructed.

53 o with rVV encoding beta-gal regulated by an early promoter activated beta-gal-specific cytotoxic T l

54 Productive infection and bICP0 early promoter activity are cooperatively transactivated

55 E2F1 or E2F2 stimulated bICP0 early promoter activity at least 100-fold in transient t

56 Activation of bICP0 early promoter activity does not necessarily lead to lat

57 F1 stimulates productive infection and bICP0 early promoter activity, in part because E2F family memb

58 t expression of HDAC8 repressed a viral SV40 early promoter activity.

59 involving inhibition of CMV major immediate early promoter activity.

60 ted transcriptional suppression of the viral early promoter activity.

61 olve a blockade of the viral major immediate-early promoter activity.

62 ion was necessary for DEX induction of bICP0 early promoter activity.

63 duced cellular factors that stimulated bICP0 early promoter activity.

64 A separate early promoter also drives bICP0 expression, presumably

65 Interestingly, a separate early promoter also drives bICP0 expression.

66 TIP60 binds to the HPV major early promoter and acetylates histone H4 to recruit Brd4

67 gative autoregulation of the major immediate-early promoter and activation of an early viral promoter

68 B motif reduce the basal activity of the Cy early promoter and decrease the levels of its induction

69 +25) was comparable in activity to the SV40 early promoter and enhancer combination.

70 riven by the human cytomegalovirus immediate-early promoter and enhancer, from a neutral locus within

71 nce-specific, requiring a region of the SV40 early promoter and enhancer.

72 decreased IE2 binding at the major immediate-early promoter and failed to show reduced acetylation of

73 SV40 early, or a hybrid cytomegalovirus/SV40 early promoter and found that the hybrid promoter improv

74 AC stimulus-response, repress the activated early promoter and induce the dormant late promoter.

75 otch1-mediated trans-activation of the bICP0 early promoter and stimulation of productive infection.

76 expression or transactivation of the native early promoters and 3' processing elements included in t

77 scription from bacterial promoters and phage early promoters and coactivating transcription from phag

78 tion-dependent activation of the E1A and E2A early promoters and E4 promoters.

79 n inhibits transcription from host and phage early promoters and is required, along with the T4 MotA

80 scription from bacterial promoters and phage early promoters and promotes transcription at phage midd

81 pUL83 recruits IFI16 to the major immediate-early promoter, and IFI16 binding at the promoter is dep

82 iral thymidine kinase gene, a representative early promoter, and of the IR5 gene, a representative la

83 virus immediate-early or the simian virus 40 early promoter, and provide an alternative to HIV-1 vect

84 at enhanced bile acid repression of the SV40 early promoter, as assayed with a luciferase reporter ge

85 2- and 70-kDa subunits, interacts with viral early promoters at both a sequence-specific core region

86 ly shown to activate transcription of an EBV early promoter, BHLF1, though a GC-rich motif which bind

87 plasmid containing the viral major immediate-early promoter but did not influence the activity of a r

88 lacZ was regulated by either the fus or esp early promoters but not when lacZ was regulated by the l

89 ors containing the cytomegalovirus immediate-early promoter, but not the ubiquitin C promoter, cooper

90 inhibited activation of the major immediate-early promoter by ppUL82 (pp71), suggesting that the UL3

91 the activation of the viral major immediate-early promoter by XBP1s and ATF6.

92 hese studies demonstrate that IE86 activates early promoters by distinct mechanisms.

93 ive cis-regulatory elements in HSV immediate-early promoters called TAATGARAT.

94 enhancer from the cytomegalovirus immediate-early promoter can enhance the U6 promoter activity, the

95 human cytomegalovirus (HCMV) major immediate early promoter) can transfect cultured cardiac cells.

96 The effect of early promoter clearance in the mutant promoters was obs

97 of the human cytomegalovirus major immediate-early promoter (CMV-IEP), which contains cAMP and nuclea

98 the CGG repeat on translation, CMV immediate-early promoter constructs, containing the FMR1 5'-UTR wi

99 imeras was measured with a basal baculovirus early promoter containing optimized Lac repressor bindin

100 n by scFv than the cytomegalovirus immediate-early promoter, containing five CREs.

101 The bICP0 early promoter contains three separate transcriptional e

102 nt protein were placed under simian virus 40 early promoter control and flanked by NotI and AscI rest

103 scent protein and the simian virus 40 (SV40) early promoter controlling neomycin phosphotransferase I

104 tely 150 kDa to bind the CMV major immediate-early promoter correlates with an increase in the level

105 ined when beta-gal was regulated by a strong early promoter coupled to a strong late promoter.

106 istone H3 acetylation at the major immediate-early promoter depends on the cis-repressive sequence to

107 sion from constitutive, immediate-early, and early promoters did not significantly increase immunodom

108 The JC virus early promoter directs cell-specific expression of the v

109 , pWRM, contains a cytomegalovirus immediate-early promoter-driven genome-length type A12 cDNA follow

110 (GFP) gene, and a cytomegalovirus immediate-early promoter driving expression of the Epo-R.

111 the different cis-acting elements of the E2-early promoter during basal transcription, the extent to

112 icomponent transcriptional complex at the E2-early promoter during transcriptional activation and the

113 t (i) the IR2P by itself downregulated EHV-1 early promoters (EICP0, TK, EICP22, and EICP27) in a dos

114 replaced with the cytomegalovirus immediate-early promoter enhancer (C-enh).

115 ere also present in the HCMV major immediate-early promoter-enhancer (MIEP/E).

116 and ie3 is controlled by the major immediate early promoter/enhancer (MIEP) and requires differential

117 ression is controlled by the major immediate early promoter/enhancer (MIEP).

118 or non-episomal plasmids containing the SV40 early promoter/enhancer (SV40 Pr/E) driving expression o

119 n deleted Ad which harbors the CMV immediate-early promoter/enhancer and a unique E4-ORF6/pIX chimeri

120 or, containing the cytomegalovirus immediate early promoter/enhancer and neomycin resistance gene, an

121 H3K27Ac was localized to the major immediate early promoter/enhancer and to a possible second enhance

122 ian promoters: the cytomegalovirus immediate early promoter/enhancer directing expression of green fl

123 , directed by the cyto-megalovirus immediate/early promoter/enhancer, was delivered through hydrodyna

124 onsive elements of the viral BRLF1 immediate-early promoter enhances Z binding to, and activation of,

125 press beta-gal only under the control of the early promoters even though late promoters were intrinsi

126 IE1 expression, the viral major IE and UL44 early promoters exhibited decreased de novo acetylation

127 HCMV major IE promoter or activate the HCMV early promoter for the 2.2-kb class of RNAs demonstrated

128 of the human cytomegalovirus major immediate-early promoter for the E1b promoter suppressed the requi

129 e dependent on the requirements of the major early promoter for transcriptional activation.

130 one in which the wild-type MLP competes with early promoters for limiting transcription factors.

131 l preinitiation complex, vPIC also activates early promoters/genes, we identify active alternate prom

132 ding a model human cytomegalovirus immediate early promoter-green fluorescent protein (GFP) transgene

133 s-repression signal from the major immediate-early promoter had no effect on the level of late RNAs b

134 regulated by sequences within the immediate early promoter (IEtu1).

135 an internal cytomegalovirus (CMV) immediate-early promoter in a self-inactivating lentiviral vector

136 eased transcription from the major immediate-early promoter in a time- and multiplicity-dependent man

137 trate that, unlike GF-1 which stimulates JCV early promoter in glial cells, overexpression of S(mu)bp

138 creased the presence of R-loops at the viral early promoter in HPV-31 (CIN612) and HPV-16 (W12) episo

139 found that R-loops accumulated at the viral early promoter in human papillomavirus (HPV) episomal ce

140 ut induced strong activation of the JC virus early promoter in nonglial cells.

141 ual TIMPs from the cytomegalovirus immediate early promoter in rat aortic smooth muscle cells.

142 suppress expression from the major immediate-early promoter in reporter assays.

143 tains the cytomegaloma virus (CMV) immediate-early promoter in tandem with the E. coli lacZpo system.

144 The E4 6/7 protein can transactivate the E2-early promoter in the absence of ATF presumably by promo

145 tumor cells may dictate the activity of JCV early promoter in these cells.

146 KAP1 also binds to EBV OriLyt and immediate early promoters in a CTAR3-dependent manner, and inhibit

147 ssed the JC virus and simian virus 40 (SV40) early promoters in glioma cells but induced strong activ

148 at Zta and CBP colocalize to viral immediate-early promoters in vivo and that overexpression of Zta l

149 P enhances Z-mediated transactivation of EBV early promoters, in reporter gene assays and in the cont

150 ses containing the cytomegalovirus immediate-early promoter induce the expression of the proapoptotic

151 moter, but not the cytomegalovirus immediate-early promoter, induced both E4-orf6/7 and TAp73 in huma

152 the control of the cytomegalovirus immediate early promoter into the VC2 vector in place of the HSV-1

153 riven by the cytomegalovirus (CMV) immediate early promoter] into mouse NIH 3T3 cells.

154 tion from latency, in part because the bICP0 early promoter is activated by DEX.

155 Transcription from adenovirus E2-early promoter is controlled by a unique array of four c

156 rast to the isolated p53 binding site, viral early promoter is repressed by p53 in H 1299 cells and t

157 Histone H3 at immediate-early promoters is acetylated at the start of infection,

158 Acetylation at immediate-early promoters is dynamic, with a high level of activat

159 one exception, transcription from tested T4 early promoters is either unaffected or, in some cases,

160 ial cell-specific transcription of the viral early promoter, is thought to account for the brain-spec

161 minating element boxA, located downstream of early promoters, is deleted.

162 In contrast to the IEtu1 promoter, the bICP0 early promoter lacks consensus type I NHR binding sites.

163 omiscuous transcription: (i) reactivation of early promoters late during infection, (ii) random trans

164 d rac1 and gp91(phox) from the CMV immediate early promoter maintained the ability to generate O(2)(-

165 1 keratinocyte clones expressed HPV-16 major early promoter (MEP)-initiated mRNAs spliced from viral

166 ys in transactivation of the major immediate-early promoter (MIEP) and production of immediate-early

167 cription (FACT) binds to the major immediate early promoter (MIEP) and that inhibition of this comple

168 The CMV major immediate-early promoter (MIEP) controls immediate-early (IE) gene

169 core promoter region of the major immediate early promoter (MIEP) from a plasmid containing the MIE

170 Transactivation of the CMV major immediate early promoter (MIEP) is essential for viral gene expres

171 human cytomegalovirus (HCMV) major immediate-early promoter (MIEP) is one of the first promoters to a

172 n human cytomegalovirus, the major immediate-early promoter (MIEP) locus contains a highly potent and

173 The major immediate early promoter (MIEP) of human cytomegalovirus (HCMV) dr

174 The major immediate-early promoter (MIEP) of human, cytomegalovirus (HCMV) c

175 ubunits are recruited to the major immediate early promoter (MIEP) that directs IE transcription.

176 ses transcription of the CMV major immediate early promoter (MIEP) through its cognate cis recognitio

177 esses transcription from the major immediate early promoter (MIEP) within 24 h.

178 e enhancer region of the CMV major immediate-early promoter (MIEP), and activity of the MIEP is stron

179 ion of histones bound to the major immediate-early promoter (MIEP), changes in patterns of methylatio

180 recently determined that the major immediate early promoter (MIEP), which is primarily responsible fo

181 d to repression of the viral major immediate early promoter (MIEP).

182 cient transactivation of the major immediate-early promoter (MIEP).

183 The HCMV major immediate early promoter (MIEP)/enhancer is a key factor in this p

184 gests that the unique architecture of the E2-early promoter necessitates the concerted interaction of

185 mal Hsp70 gene promoter or minimal immediate early promoter of cytomegalovirus (CMV) and a combinatio

186 on controlled by part of the major immediate early promoter of human cytomegalovirus (CMV), show GFP

187 represent an ideal candidate pathway linking early promoters of diabetes, especially overnutrition an

188 ved with Oct elements found in the immediate-early promoters of herpes simplex virus type 1(HSV-1).

189 o induce the transcriptional activity of the early promoters of these HPV types.

190 d, whether a cytomegalovirus (CMV) immediate-early promoter or a chicken beta-actin promoter was used

191 was controlled either by the simian virus 40 early promoter or by the SIV 5' long terminal repeat reg

192 er the human cytomegalovirus (CMV) immediate early promoter or the caprine arthritis-encephalitis vir

193 Unlike P1 early promoters, P1 late promoters are not recognized by

194 hGFP), placed under the control of the human early promoter (P2) for the oligodendrocytic protein cyc

195 An HPV31b early promoter, P97, and a differentiation-induced promo

196 --E2 (16-E8--E2) is independent of the major early promoter, P97, and is modulated by both specific s

197 e expression was driven by the CMV immediate-early promoter (pCMV-HA).

198 rom a common transcript initiating at the N4 early promoter Pe3.

199 dentical sequences located downstream of the early promoters, pL and pR, were first identified as cis

200 We found that the HPV31b major early promoter precisely maps to nucleotide (nt) 99 (P99

201 e.g., the synthesis of a very abundant short early promoter proximal RNA, are also described.

202 cessary for replication, and mutation of the early promoter-proximal site (BS4) led to a fourfold inc

203 structural model proposes that the immediate early promoter region is localized on the periphery of t

204 ence of acetylated histones in the immediate-early promoter region.

205 rection under control of the cytomegalovirus early promoter reproduced the anchorage-independent grow

206 peat (LTR) and the cytomegalovirus immediate-early promoter, respectively.

207 RNA and inhibited transcription from the HPV early promoter, revealing a new role for NF90/NF45 in HP

208 studies demonstrated that occupancy of bICP0 early promoter sequences by KLF4 and type I NHR is signi

209 C/EBP-alpha directly interacted with bICP0 early promoter sequences that were necessary for trans a

210 CP4 and bICP0 genes share a common immediate-early promoter, suggesting that this promoter was not co

211 trate that a small segment of the Sex-lethal early promoter that contains Runt-binding sites mediates

212 E) and NFkB sites within the Major Immediate Early Promoter that drives IE1 transcription contribute

213 The bICP0 gene also contains a novel early promoter that was activated by DEX in mouse neurob

214 oters, such as the cytomegalovirus immediate-early promoter, the IFN-beta promoter, and a promoter co

215 ts in transcription from the major immediate early promoter, the production of extracellular virions,

216 s, the human cytomegalovirus (CMV) immediate-early promoter, the Rous sarcoma virus (RSV) long termin

217 ent of RNA polymerase II to a representative early promoter (thymidine kinase [TK]).

218 required for the efficient activation of an early promoter (tk).

219 Unlike other early promoters to which the R protein binds directly, i

220 ol of the thymidine kinase promoter, a viral early promoter, to permit easy detection of infected cel

221 NF90 activated the cytomegalovirus immediate-early promoter, to which it was not targeted.

222 RB binding on its own is not sufficient for early promoter transactivation by the E1A amino terminus

223 the control of the cytomegalovirus immediate-early promoter (vCMVp-lacZ).

224 ntrol of the human cytomegalovirus immediate early promoter (vector SHN) or the HSV latency active pr

225 nal control of the cytomegalovirus immediate-early promoter (VEE DNA).

226 us under the human cytomegalovirus immediate-early promoter was expressed in SK-N-SH cells and blocke

227 er the control of the simian virus 40 (SV40) early promoter was inserted into the intergenic region b

228 Moreover, the simian virus 40 early promoter was rendered p21 suppressible by introduc

229 AF-1 transgenic mice, in which CMV immediate-early promoter was used to direct expression of the SAF-

230 ch the protein regulates the major immediate-early promoter, we utilized a mutant virus expressing an

231 e control of cytomegalovirus (CMV) immediate early promoter were constructed.

232 Remarkably, only those rVV employing early promoters were capable of prolonging the survival

233 the tissue-specific regulation of the viral early promoter which is responsible for the production o

234 BRLF1 activation of the SM early promoter (which occurs through a direct binding me

235 human cytomegalovirus (HCMV) major immediate-early promoter, which contains two such sites.

236 This vector contains an SV40 early promoter, which drives expression of the green flu

237 ficiently repress the simian virus 40 (SV40) early promoter, which primarily consists of Sp-1 sites;

238 ive regions (ERR) were identified within the early promoter, with one adjacent to the TATA box (ERR1)

239 d contrast, in HH514-16 cells, the immediate-early promoters Zp and Rp were simultaneously activated

240 rgistically activating the two EBV immediate early promoters (Zp and Rp).