ライフサイエンスコーパス: ectromelia virus

1 sepox, a disease caused by the Orthopoxvirus ectromelia virus.

2 ypox viruses, which are highly homologous to ectromelia virus.

3 ntranasal inoculation with 40,000x LD(50) of ectromelia virus.

4 determined and allows for classification of ectromelia viruses.

5 nd one strain each of cowpox, rabbitpox, and ectromelia viruses.

6 cells prevent mousepox, a disease caused by ectromelia virus, a close relative of the virus of human

7 vaccinia virus DNA into cells infected with ectromelia virus and assaying for MAb reactivity, we map

8 resent study, we used the mouse-specific OPV ectromelia virus and mice deficient in CD40, B cells, or

9 ble to mousepox, a disease that is caused by ectromelia virus and that is the mouse homolog of human

10 nstrate that the p28 proteins encoded by the ectromelia virus and the variola virus possess E3 ubiqui

11 er orthopoxviruses; however, four strains of ectromelia virus (ECT) examined contained an intact crmD

12 The orthopoxviruses ectromelia virus (ECTV) and vaccinia virus (VACV) expres

13 gold standard vaccine--as the immunogen and ectromelia virus (ECTV) as the pathogen to demonstrate t

14 Ectromelia virus (ECTV) causes mousepox, a surrogate mou

15 Ectromelia virus (ECTV) encodes an IFN-gamma-binding pro

16 tions with smallpox in humans or the related ectromelia virus (ECTV) in mice.

17 d morbidity and mortality during respiratory ectromelia virus (ECTV) infection in mice even when trea

18 Studies of the effects of ectromelia virus (ECTV) infection on NK cells demonstrat

19 sed substantial pathology during respiratory ectromelia virus (ECTV) infection, a surrogate model for

20 at in mice, CD4-CTL are important to control ectromelia virus (ECTV) infection.

21 for the resistance of C57BL/6 mice to lethal ectromelia virus (ECTV) infection.

22 homolog of VCP is able to bind VACV A56, the ectromelia virus (ECTV) VCP homolog is only able to bind

23 e their natural resistance to wild-type (WT) ectromelia virus (ECTV) when chronically infected with l

24 hat NF-kappaB is essential for resistance to ectromelia virus (ECTV), a mouse orthopoxvirus related t

25 o highly related (>92% homology) poxviruses: ectromelia virus (ECTV), a natural mouse pathogen, and v

26 K3 and MLKL in controlling the Orthopoxvirus ectromelia virus (ECTV), a natural pathogen of the mouse

27 Ectromelia virus (ECTV), an orthopoxvirus that naturally

28 a lethal disease caused by the orthopoxvirus ectromelia virus (ECTV), and that this resistance requir

29 ecies vaccinia virus, and the mouse pathogen ectromelia virus (ECTV), form two types of infectious vi

30 The F13L ortholog in ectromelia virus (ECTV), the agent of mousepox, is EVM03

31 m mousepox, a lethal viral disease caused by ectromelia virus (ECTV), the murine counterpart to human

32 stributing within the draining lymph node of ectromelia virus (ECTV)-infected mice or at becoming eff

33 y HLA-B*07:02 (B7.2) molecules in a mousepox/ectromelia virus (ECTV)-infection, B7.2 transgenic mouse

34 ll required for resistance to infection with ectromelia virus (ECTV).

35 2A is selectively required for resistance to ectromelia virus (ECTV).

36 inia virus (VACV) in protecting mice against ectromelia virus (ECTV).

37 uman smallpox virus and the mouse-equivalent ectromelia virus (ECTV; an agent of mousepox), encode im

38 infected with CL13 succumb to challenge with ectromelia virus (ECTV; the agent of mousepox) and that

39 ion of humans (smallpox) and mice (mousepox [ectromelia virus {ECTV}]) despite the lack of a natural

40 Whereas the human variola virus and mouse ectromelia virus encode one vTNFR, the broad host range

41 of these immunomodulatory activities in the ectromelia virus-encoded CrmD.

42 s important for recovery from infection with ectromelia virus (EV), a natural murine poxvirus pathoge

43 Mice infected with a p13 deletion mutant of ectromelia virus had elevated cytotoxicity for YAC-1 tum

44 Similar to the human pathogen variola virus, ectromelia virus has a limited host range and provides a

45 The ectromelia virus homolog of the vaccinia virus A33R gene

46 ystal structure of an orthopoxvirus IL-18BP, ectromelia virus IL-18BP (ectvIL-18BP), in complex with

47 NSC61610) that disrupt hIL-18 binding to the ectromelia virus IL-18BP.

48 Ectromelia virus-infected cells expressing the major his

49 observation that the protein synthesized by ectromelia virus-infected cells reacted with only one of

50 ss of Clr-b cell-surface protein upon VV and ectromelia virus infection of murine cell lines and bone

51 report the impact of vaccinia virus (VV) and ectromelia virus infection on expression of Clr-b and Cl

52 alternative pathways are required to survive ectromelia virus infection.

53 In this study, we characterized the ectromelia virus inhibitor of complement enzymes (EMICE)

54 The EVM1 protein encoded by Ectromelia virus is a member of a highly conserved famil

55 major histocompatibility complex inhibitor, ectromelia virus macrophage host range protein, myxoma v

56 tical determinant of viral virulence for the ectromelia virus (mousepox virus) in a murine infection

57 in vivo Previous studies have shown that the ectromelia virus orthologue of A55 interacts with Cul3 i

58 ll responses, in the absence of Ab responses ectromelia virus persists.

59 In summary, ectromelia virus produced EMICE within a few hours of an

60 ere we show that during acute infection with ectromelia virus, the mouse homolog of the human virus o

61 Intraperitoneally inoculated ectromelia virus was uniformly lethal and achieved simil

62 of nine genes in 12 isolates and strains of ectromelia virus, which causes a smallpox-like disease (