ライフサイエンスコーパス: effective concentration

1 -response curves and estimate ECx values (x% effective concentration).

2 anamivir (3-7-fold increase in IC(50) or 50% effective concentration).

3 gainst chemotherapeutic agents (half-maximal effective concentration).

4 eral features of a worm-like chain model for effective concentration.

5 nefficiently charged, and 80% reduced in its effective concentration.

6 follow a Michaelis-Menten-like dependence on effective concentration.

7 etrate the bladder wall and accumulate to an effective concentration.

8 ay be regions where only one drug reaches an effective concentration.

9 good agreement between in vivo and in vitro effective concentrations.

10 he cooperation of EGF at lower than normally effective concentrations.

11 unds by themselves were not cytotoxic at the effective concentrations.

12 nctional effects, but different half-maximal effective concentrations.

13 erify the success of injections and estimate effective concentrations.

14 outer membrane are typically toxic at their effective concentrations.

15 to 15,000-fold higher than their therapeutic/effective concentrations.

16 d biocides from the membrane, lowering their effective concentrations.

17 is active against T. gondii tachyzoites (50% effective concentration, 0.2 nM).

18 promotes chondrocyte differentiation (median effective concentration = 100 nM), shows chondroprotecti

19 Comparison of effective concentration (50%) values indicates that proB

20 ethylene (E) production demonstrated similar effective concentration(50) values of 68, 45, and 87 fmo

21 gens, and discharge microbicidal peptides at effective concentrations accordingly.

22 The median voxilaprevir 50% effective concentration against NS3 from protease inhibi

23 rotein-protein interaction by increasing the effective concentration and enabling spatial co-ordinati

24 ve understanding of the relationship between effective concentration and linker sequence will be cruc

25 s also indicate that C3, administered in the effective concentration and timeframe, may play a pivota

26 ther, the link between them influences their effective concentrations and therefore the frequency of

27 nomeric peptides, consistent with the higher effective concentration, and hence increased aggregation

28 The inhibitory concentration, effective concentration, and selectivity index for Leflu

29 drug levels that paralleled the human median effective concentration, and with limited toxicities.

30 inositol monophosphatase at therapeutically effective concentrations, and it has been hypothesized t

31 Effective concentrations are rarely measured experimenta

32 asing Isc was 5'adenosine-triphosphate (ATP; effective concentration at half maximal response [EC50]

33 The effective concentration at half-maximum values of the pe

34 anchors to increase protein localization and effective concentration at sites of injury, cell activat

35 The amount of drug ejected, and its effective concentration at the tip, has historically bee

36 odeling we attribute this effect to variable effective concentrations at the mitochondria surface of

37 of virus to cells at 4 degrees C at the same effective concentrations at which they prevent viral inf

38 ntration-versus-time curve over half-maximal effective concentration (AUC:EC50) of 108.6 is estimated

39 ffects of nociceptin (0.31 mM, the maximally effective concentration), but not endomorphin-2 (0.6 mM;

40 over 12 weeks and exceeded the in vitro 50% effective concentration by 5000-fold in vaginal fluid by

41 thus demonstrate that direct measurement of effective concentrations can be used in systematic studi

42 These effective concentrations caused low toxicity to normal l

43 hits, a new assay (summarized in a cytocidal effective concentration (CEC(50))) was established, as p

44 Of these, thirteen were found to harbour effective concentrations commensurate with probable achi

45 a dose-dependent reduction in VZV yield (50% effective concentration, congruent with 8 microM).

46 e fact that FCS and FRAP report on different effective (concentration dependent) diffusion coefficien

47 , which delivers therapeutic molecules at an effective concentration directly to the brain, may provi

48 ion for delivery, often do not accumulate in effective concentrations distant from vasculature and ar

49 The medium effective concentration EC(50) (Me(2+)) suggests A. anop

50 ied by population sequencing, the median 50% effective concentration (EC(50) ) values for BMS-790052

51 y under posttreatment conditions [median 50% effective concentration (EC(50)) = 3.80 nM to 1.73 muM;

52 e with a roughly 70-fold better half-maximal effective concentration (EC(50)) against Shiga toxin cyt

53 tation showed a 2.9-fold increase in the 50% effective concentration (EC(50)) for adefovir compared t

54 0.2 pM tissue factor (TF), the half maximal effective concentration (EC(50)) for DHG inhibition was

55 ons approximately 100-fold the antiviral 50% effective concentration (EC(50)) for genotype 1 virus.

56 iciently neutralized LT in vitro, with a 50% effective concentration (EC(50)) of 0.1 nM, and provided

57 desivir inhibited Ituri Ebola virus at a 50% effective concentration (EC(50)) of 12nM (with a selecti

58 this technique was used to estimate the 50% effective concentration (EC(50)) of 14 micro M.

59 AAO decreased keratinocyte viability with an Effective Concentration (EC(50)) of 5.1 mug/mL.

60 s astrovirus replication in vitro with a 50% effective concentration (EC(50)) of approximately 1.47 m

61 The detected values of half maximal effective concentration (EC(50)) of lauric acid on P. ac

62 t A(2A) occupancy in humans, based on median effective concentration (EC(50)) values estimated from t

63 /Cys270Ser double mutants had similar median effective concentration (EC(50)) values for ADP and 2-me

64 tion response profiles, and the half-maximal effective concentration (EC(50)) values for glucose were

65 The half maximal effective concentration (EC(50)) was 0.37 muM for maltos

66 neuronal isoform, KCNQ2/KCNQ3 [half maximal effective concentration (EC(50)), 60 +/- 20 nM], and the

67 and activates human GPR7 or GPR8 with median effective concentrations (EC(50)) of 0.23 nM and 15.8 nM

68 In KB8-5 cells, the median effective concentrations (EC(50)) of MDR modulators LY33

69 protein that exhibits picomolar half-maximum effective concentrations (EC(50)) towards replicons expr

70 s and cell culture infectious virus with 50% effective concentrations (EC(50)s) of 46.8 and 16.1 pM,

71 ibits both murine hepatitis virus (MHV) (50% effective concentration [EC(50)] = 0.17 muM) and Middle

72 cose-excited neurons increased (half-maximal effective concentration [EC(50)] = 0.54 mmol/l) and gluc

73 induce the dimerization of Tp34; Cu(2+) (50% effective concentration [EC(50)] = 1.7 muM) and Zn(2+) (

74 catabolites, caused cell death (half-maximal effective concentration [EC(50)] = 2 nM) by a mechanism

75 tration-dependent contractions (half-maximal effective concentration [EC(50)] = 2.5 microM and 3.9 nM

76 its time- and dose-dependently (half maximal effective concentration [EC(50)] = 27 +/- 3 nM) oxygen/g

77 delta small molecule inhibitor (half-maximal effective concentration [EC(50)] = 8nM).

78 The half maximal effective concentration, EC(50), for the CRF-induced cAM

79 with the following agonist potencies (median effective concentration; EC(50)): travoprost acid (EC(50

80 CXCR4(+) cancer cells in vitro (half maximal effective concentration (EC50 ) approximately 80-100 pM)

81 r hand, with large variation of half-maximum effective concentration (EC50) across tested NPs (5.4 to

82 ctivation, causing a 66% decrease in the 50% effective concentration (EC50) for activation through CD

83 The half-maximal effective concentration (EC50) for the dendrimer against

84 e effectively neutralized by 81.39a at a 50% effective concentration (EC50) of <0.01 to 4.9 mug/ml.

85 depolarizing potentials with a half-maximal effective concentration (EC50) of 1.8 muM.

86 ng several noxious stimuli, exhibiting a 50% effective concentration (EC50) of 12.6 +/- 3.2 muM.

87 n, DLD-4, inhibited TcdB with a half maximal effective concentration (EC50) of 4 pM in vitro, represe

88 ependently activates Kir6.2/SUR1 with a half-effective concentration (EC50) of approximately 7 muM, i

89 nsition for the Asn-700 constructs; the half-effective concentration (EC50) of Ca Asn-700 was 390 mic

90 We found the half maximal effective concentration (EC50) of lutropin to have an av

91 rane at concentrations near the half maximal effective concentration (EC50) of several microorganisms

92 it is highly unlikely that ASM half-maximum effective concentration (EC50) or Vmax contribute to AHR

93 cells and prostaspheres, with a half-maximal effective concentration (EC50) ranging from a multiplici

94 The half-maximal effective concentration (EC50) value of the time-resolve

95 se-response characteristics and half-maximal effective concentration (EC50) values using image-based

96 re was no significant difference between the effective concentration (EC50)-which is the dilution of

97 HE, 9-OHPHE, and 1,9-OHPHE, were toxic, with effective concentrations (EC50's) ranging from 0.5 to 5.

98 ion is linked to the toxicity of ILs, median effective concentrations (EC50) and critical micelle con

99 Half maximal effective concentrations (EC50) obtained after 10 min bi

100 within an order of magnitude of half-maximal effective concentrations (EC50) of nontarget invertebrat

101 ll lines (HeLa, SK-MEL-28, A549, MCF-7) with effective concentrations (EC50) typically below 5 nM, at

102 The half-maximal effective concentrations (EC50) were 2.4x10(-7)M and 1.3

103 d compared the phenotypic sensitivities (50% effective concentration [EC50]) of mutant and wild-type

104 osine monophosphate inhibition (half maximal effective concentration [EC50]: 0.21 +/- 0.18 vs. 1.38 +

105 pendent antiestrogenic activity half maximal effective concentration [(EC50): 4.5muM)].

106 ing 95% confidence intervals of their median effective concentrations: EC50(PBZ) = 0.07-0.09 mM; EC50

107 We determined the effective concentrations (EC50s) and the toxicities (LD5

108 aboratory HIV-1 strain (HIV-1(WT)), with 50% effective concentrations (EC50s) of 3.0 to 49 nM, and ex

109 Overall, half maximal effective concentrations (EC50s) were lower than 176 nM

110 ir (3-, 14-, and 3-fold increases in the 50% effective concentrations [EC50s], respectively).

111 and CD4(+) T cells were used to identify 90% effective concentration (EC90) ratios of TFVdp to dATP a

112 proportion of participants reaching the 90% effective concentration (EC90) was 77% after 5 doses and

113 of pregnant women having a Ctrough below the effective concentration (EC90).

114 f U. parvum occurred at 6.6 days, with a 95% effective concentration (EC95) of 39 ng/mL for the maxim

115 These data indicate that ATRA at effective concentrations eliminated ImC, improved myeloi

116 s spp. under all conditions, but the minimal effective concentration end point, defined as the lowest

117 We have directly measured the effective concentrations enforced by disordered protein

118 of disorder in the RAM linker region on the effective concentration enhancement of Notch transcripti

119 esponse threshold away from the basal median effective concentration established by ligand-receptor i

120 alysis showed that although in vitro derived effective concentrations exceeded the levels measured in

121 ly attached response regulator domain, whose effective concentration exceeds that of all soluble resp

122 We show that effective concentrations follow simple geometric models

123 ncentration of drug that displayed a minimum effective concentration for Aspergillus spp.

124 The half maximal effective concentration for Cryptosporidium parvum in HC

125 atekeeper greatly increased the half maximal effective concentration for ibrutinib and A419259.

126 redicted a significantly higher half-maximal effective concentration for IL-1beta-induced pathway act

127 ensitivity to bortezomib than FL (median 50% effective concentration for viability, 209 nmol/L v 1,31

128 Daclatasvir 50% effective concentrations for 10 patient-derived NS5A seq

129 turally occurring mAbs with low half-maximal effective concentrations for binding, 5 of which possess

130 the six-Cys form, were also used to estimate effective concentrations for forming a third disulfide o

131 he V787E recombinant virus, the half maximal effective concentrations for ganciclovir, foscarnet, and

132 Using polymer theory, effective concentrations for interactions between domain

133 ns also reproduced experimentally determined effective concentrations for the formation of disulfide

134 heir correlation with either MICs or minimum effective concentrations (for caspofungin only), and the

135 0.5 and 1 mumol/g WMS) suggested a 'minimum effective concentration' for epicatechin and caffeic aci

136 Estimated effective concentrations from the BLM-like parametrizati

137 s (likely late endosomes or lysosomes) where effective concentrations (>2.5 microM) were greater than

138 were used to derive species-specific median effective concentrations, i.e., pH50, and pH10, via logi

139 rum concentration at sacrifice resembled the effective concentration in vitro.

140 ited by adiponectin quaternary structure and effective concentrations in circulation.

141 n, spent substantial periods (>12 h/d) below effective concentrations in hard-to-treat lesions, such

142 s, crossed the blood-brain barrier, achieved effective concentrations in mouse brain, prevented ethan

143 fflux and metabolism of ARV drugs to prolong effective concentrations in target cells need to be deve

144 gical effect data are generally expressed as effective concentrations in the external exposure medium

145 DENV-1-4 and DENV-1 ADE infections, with 50% effective concentrations in the low micromolar range.

146 at multiple stages of the viral lifecycle at effective concentrations in the pM to nM regimes, while

147 chemical pesticides are required to achieve effective concentrations in the rhizosphere, which resul

148 es suppressed both HIV-1 and HSV-2 at median effective concentrations in the submicromolar range in e

149 ne compound, BILS 179 BS, displayed an EC50 (effective concentration inhibiting viral growth by 50%)

150 First, antibiotics are frequently below effective concentrations inside granulomas, leading to b

151 n by the liver is such that a half-maximally effective concentration is at or slightly below the horm

152 ative tetrameric TTR; however, their minimal effective concentration is in the micromolar range.

153 a natural product with no known toxicity at effective concentrations, it provides a potential therap

154 al activity concentration (AC50), and lowest effective concentration (LEC).

155 ion in a dose-response manner with a minimum effective concentration </= 0.5muM.

156 Moreover, at effective concentrations (<5 muM), EHop-016 does not aff

157 oint for reading caspofungin was the minimum effective concentration (MEC).

158 ng), plasma pharmacokinetic (time-to-minimum-effective-concentration (MEC, 25 ng/mL) and pharmacodyna

159 ution (MIC), microscopic evaluation (minimal effective concentration [MEC]), and a new method to meas

160 (percentage of time greater than the minimum effective concentration [MEC], 96-h area under the plasm

161 ee echinocandins--anidulafungin (50% minimum effective concentration [MEC50], 0.007 microg/ml; MEC90,

162 tive against Aspergillus spp. (MIC90/minimum effective concentration [MEC90] range, 0.015 to 2 mug/ml

163 e ankyrin domain of NICD with CSL through an effective concentration mechanism.

164 od), with the broth dilution MICs or minimum effective concentrations (MECs) (CLSI M38-A method) of f

165 The MICs or minimal effective concentrations (MECs) of amphotericin B, voric

166 A. terreus to caspofungin (MICs and minimum effective concentrations [MECs]) by using standard RPMI

167 d 72 h) and two end points (MICs and minimum effective concentrations [MECs]) for evaluating anidulaf

168 At maximally effective concentrations, METH released twice as much [C

169 centration, mainly because of the lack of an effective concentration normalization method for cell me

170 concentration dependent with a half maximal effective concentration of 0.20 micromol/L.

171 -dependently caused pain with a half-maximal effective concentration of 0.31 mum Coinjection of A-967

172 d that GLP-1 enhances GSIS at a half-maximal effective concentration of 0.4 pM.

173 n in in vitro cytotoxicity assays with a 50% effective concentration of 0.65 ng/ml for the lead candi

174 oietic progenitor cells (HPCs) with a median effective concentration of 1 microg/mL but not after exp

175 The effective concentration of 1-aminoanthracene required to

176 site infection in vitro, with a half maximal effective concentration of 100 nM.

177 cing four peptides in a box of water with an effective concentration of 158 mg/ml to enhance the rate

178 ensors can reliably detect SEB at 10-100 fg (effective concentration of 2.5 and 25 fg/mL) in complex

179 nd inside the nucleotide site of S1, with an effective concentration of 20 mM as judged by the concen

180 a Microcystis aeruginosa with a half maximal effective concentration of 21 and 5 mug/mL, respectively

181 pleconaril inhibits EV-D68 at a half-maximal effective concentration of 430 nanomolar and might, ther

182 270430 specific binding, with a half maximal effective concentration of 69.4 ng/mL in plasma PF-05180

183 lemizole's antiviral effect is moderate (50% effective concentration of 8 microM against an HCV genot

184 Assays for measuring the effective concentration of a ligand for promotion of tub

185 eration in intracellular environment and the effective concentration of AAO released after being subj

186 A maximally effective concentration of activated RhoA also increased

187 y 2-fold, increase the response to maximally effective concentration of agonist 4-fold, and the racem

188 a brief (5-8 ms) application of a maximally effective concentration of agonists was 319 +/- 34 ms.

189 The effective concentration of an HR is limited by the stoic

190 n of glycogen synthase (GS) with a maximally effective concentration of approximately 2 micromol/l.

191 ith a 50% inhibitory concentration and a 50% effective concentration of approximately 50 nM.

192 We find that side chains lower the effective concentration of backbone amides in water lead

193 Additional dilution of the effective concentration of backbone amides is achieved t

194 original and control populations if the 20% effective concentration of Cd was considered (cross-tole

195 Domain positioning impacts the effective concentration of cTnI[148-158] presented to cN

196 ings indicate that factors that increase the effective concentration of CXCR4 enhance FIV infectivity

197 ous oxidative membrane damage lowers the 50% effective concentration of direct-acting antivirals in v

198 ate of CO production on Au by increasing the effective concentration of dissolved CO2 near the electr

199 This is the first time that a steady, effective concentration of drug is maintained in the tea

200 In an attempt to increase the effective concentration of each component of a pathway o

201 unds were found to be sufficient to mimic an effective concentration of enzymatic superoxide dismutas

202 tions show that the glycocalyx increases the effective concentration of FGFs, leading to FGF oligomer

203 c side of the pore is characterized by a low effective concentration of free FG repeats and a weak FG

204 Here we determine the most effective concentration of genomic DNA, and also show th

205 n (1 to 100 microg/ml) independently; (3) an effective concentration of glucose (500 microg/ml) with

206 NR1/NR2C receptors activated by a maximally effective concentration of glutamate and glycine had two

207 plication of 50 muM PYD-106 with a maximally effective concentration of glutamate and glycine increas

208 ty of PEG scaffolds is too high to raise the effective concentration of glyco ligands above a value t

209 hypothesize this translocation provides the effective concentration of H2O2 required to selectively

210 The effective concentration of IQNPA that neutralized 50% of

211 f various concentrations of L-glutamine, the effective concentration of L-glutamine in the M. tubercu

212 an IgE-coated sensor chip suggested that the effective concentration of lz-CD23 was lower at the high

213 A fluorescence method for measuring the effective concentration of Mg2+ in the presence of an RN

214 are derived from an assay that measures the effective concentration of Mg2+ in the presence of RNA.

215 concentration was >10 times the half maximal effective concentration of miltefosine (median, 30.2 day

216 At a maximally effective concentration of modulator, the current levels

217 Realizing the safe and effective concentration of nano-particles and the irradi

218 yte from the junction and an increase in the effective concentration of negatively charged species (s

219 lectivity by the Tenax TA polymer allowed an effective concentration of PAHs while eliminating n-hexa

220 nuggets observed was used to recalculate an effective concentration of precious metals for the analy

221 This lowers the effective concentration of protein available for binding

222 cal dosimeter is needed that can measure the effective concentration of radical that is delivered to

223 diffusion corridors, thereby increasing the effective concentration of select membrane proteins to p

224 on of tethered sigma70, we conclude that the effective concentration of sigma70 in E. coli (i.e., its

225 However, the effective concentration of sigmas in vivo, and the exten

226 Based on measurement of the effective concentration of tethered sigma70, we conclude

227 iated molecule domain of Notch increases the effective concentration of the ankyrin domain for its bi

228 or and a PIC component but only increase the effective concentration of the correctly oriented PIC co

229 yme to be "tethered", thereby increasing the effective concentration of the histone tail and permitti

230 protein U1A into dimers and trimers, a high effective concentration of the monomers is achieved, tog

231 ed state, a dramatic loop opening lowers the effective concentration of the reacting species.

232 catalyzing ubiquitination by increasing the effective concentration of the substrate lysine at the E

233 The effective concentration of the tetraalkylammonium phenox

234 ngle channel currents activated by maximally effective concentrations of agonist but only had modest

235 suggest a novel strategy for achieving more effective concentrations of anti-oxidants in lipoprotein

236 Effective concentrations of antiretrovirals in the femal

237 The responses to maximally effective concentrations of ATP and UTP were not additiv

238 performed on P. aeruginosa with and without effective concentrations of AZM.

239 rrier (BTB) significantly limits delivery of effective concentrations of chemotherapeutic drugs to br

240 hat treatment of human cancer cells with low effective concentrations of DAP specifically activates t

241 Spectra of the largest clusters, which have effective concentrations of divalent calcium that are le

242 iles of PiDSD, determined the enhanced local effective concentrations of DNA probes that are involved

243 s caused cell proliferation, with the lowest effective concentrations of E(2) (10(-15) M) > E(1) (10(

244 Gel formation serves to reduce the effective concentrations of free HBpin and (n)BuNH(2) an

245 ld potentiation of the response to maximally effective concentrations of glutamate and glycine but ha

246 Effective concentrations of H(2)O(2) at which 50% of I(s

247 ssion compared with that seen with maximally effective concentrations of IFN-gamma alone.

248 Both concentrations are similar to the effective concentrations of IL-8 and less than the effec

249 ons of insulin (1 to 100 microg/ml); and (4) effective concentrations of nicotine (250 microg/ml), gl

250 Combined application of maximally effective concentrations of NMDA and DOM elicited a grea

251 ive concentrations of IL-8 and less than the effective concentrations of other neutrophil chemoattrac

252 These factors may affect the effective concentrations of the AM in vivo.

253 on and, thus, the production of ecologically effective concentrations of the antibiotic.

254 These equilibrium constants represent effective concentrations of the Cys thiols and ranged fr

255 e (transient) native structure increases the effective concentrations of the reactive thiol and disul

256 This greatly reduces the effective concentrations of therapeutic agents at the ta

257 ditional benefits by achieving sustained and effective concentrations of therapeutic antibodies direc

258 However, in the presence of effective concentrations of these protein phosphatase in

259 arly phase I clinical testing indicates that effective concentrations of TNFalpha can be delivered to

260 To increase the "effective concentration" of the interacting molecules, t

261 e chemical activity (Ea-50) of 0.029 and the effective concentration on a lipid basis (EC(lipid, eq.)

262 The effective concentration p depends on the length of the l

263 activity (P = .001) and a lower half maximal effective concentration (P = .002) than did Ara h 6 when

264 (5) At effective concentrations plausibly present in yeast mito

265 cytes or retinal pigment epithelial cells at effective concentrations; protects human aortic endothel

266 At maximally effective concentrations, PTH and FGF23 equivalently dec

267 five different concentrations that cover the effective concentration range needed for downstream cell

268 The observed effective concentration ranges of both compounds was bel

269 luding rank order of inhibitor potencies and effective concentration ranges.

270 both a dose- and time-dependent manner with effective concentrations ranging from 40 to 100 muM.

271 in the 100 nM range, a value similar to the effective concentration required for observation of the

272 The in vitro median effective concentration required to induce a 50% effect

273 se of GS-9190 at 1, 10, and 20 times its 50% effective concentration, respectively.

274 At a maximally effective concentration, Rg3 shifted the half-point of v

275 sf1 in Saccharomyces cerevisiae at a similar effective concentration seen in mammalian cells.

276 l (0.2 mg/L), 10-fold lower than the minimal effective concentration shown to promote Abeta clearance

277 , can introduce oligonucleotides at a higher effective concentration than conventional transfection a

278 eutic resistance, with a higher half-maximal effective concentration than that of cells that had not

279 The effective concentration that scavenged 50% (EC50) of the

280 rophylactic utility and identify lower bound effective concentrations that can guide dose selection i

281 regulate interdomain contacts, and thus the effective concentrations that govern intramolecular reac

282 sis of the combination revealed that the 90% effective concentration threshold of posaconazole activi

283 We estimated the 50% effective concentration to be approximately 0.7 microM f

284 ring part of the polyphenols, reducing their effective concentration to bind saliva proteins.

285 RASs in NS5A that increased the half-maximal effective concentration to ledipasvir by more than 100-f

286 o provide controlled release of cisplatin in effective concentrations to kill the tumor cells that th

287 At effective concentrations, UNC0638 did not alter cell mor

288 n this subject was 117 nM and the median 50% effective concentration value for a GT-1a H77c replicon

289 F concentrations were above the half-maximal effective concentration value in all patients, and all s

290 (5)(0) x 100, where EC(5)(0) is half maximal effective concentration) value was independently associa

291 the cardiac MPS show half maximal inhibitory/effective concentration values (IC(5)(0)/EC(5)(0)) that

292 essing mouse B and T cells with half-maximum effective concentration values around 500 pM, but had no

293 In vitro 50%/90% maximal effective concentration values for hydroxychloroquine sh

294 BAL, which corresponded to the half-maximal effective concentration values for protease release seen

295 ost potent anti-IAV effect with half-maximal effective concentration values of 0.14 and 0.11 muM, res

296 were found that exhibit EC(50) (half-maximal effective concentration) values for c-di-GMP as low as 9

297 F1609-0442, and F1750-0048) having EC50 (50% effective concentration) values of 4.8 +/- 2.3, 12.5 +/-

298 aused prolactin release at 1 min; the lowest effective concentrations were 10(-11) M E(2), 10(-10) M

299 These effective concentrations were approximately 100 and 10 M

300 no methods exist to systematically vary the effective concentration within this intramolecular inter