ライフサイエンスコーパス: effective treatment

1 nts can be severe, and presently there is no effective treatment.

2 fractory to chemotherapies and thus lack any effective treatment.

3 causes a nearly 100% mortality rate without effective treatment.

4 and Janus kinase inhibitors appear to be an effective treatment.

5 Talc pleurodesis is a common and effective treatment.

6 difficult to identify, which may compromise effective treatment.

7 system to ensure adults and children receive effective treatment.

8 esponse to steroid therapy, it represents an effective treatment.

9 pproximately 25% of human cancers and has no effective treatment.

10 ble ectopic mineralization disorders without effective treatment.

11 promote drug relapse have yet to produce an effective treatment.

12 vasculature contributes to the difficulty in effective treatment.

13 ividuals worldwide and for which there is no effective treatment.

14 apabilities, and there is currently no fully effective treatment.

15 ory cholangiopathy with no known etiology or effective treatment.

16 e ANS and SAN to HRV are not clear, impeding effective treatment.

17 COVID-19 pandemic prior to the advent of an effective treatment.

18 devastating epidemic for which there was no effective treatment.

19 llular carcinoma (HCC), a malignancy with no effective treatment.

20 the tropical and subtropical world, with no effective treatment.

21 medical condition with few or no options for effective treatment.

22 g for culture-based diagnostics to select an effective treatment.

23 early-childhood brain tumor without standard effective treatment.

24 rapy (OPAT) is a widely used, safe, and cost-effective treatment.

25 ted heart impairment is lacking a clinically effective treatment.

26 brain tumors for which there is currently no effective treatment.

27 egenerative condition for which there are no effective treatments.

28 registered with the intention of discovering effective treatments.

29 ng between disorder subtypes and identifying effective treatments.

30 er together with other key targets to derive effective treatments.

31 Cov-2 will result into the identification of effective treatments.

32 tion or even death and urgently require more effective treatments.

33 medicine today because of a general lack of effective treatments.

34 ular mechanisms among diseases and designing effective treatments.

35 to develop better diagnostic tools and more effective treatments.

36 NAMPT inhibitors, and pave the way for more effective treatments.

37 nesis is poorly understood, and there are no effective treatments.

38 patients remains below 7% due to the lack of effective treatments.

39 hich is critical for the development of more effective treatments.

40 ineering, and microtechnology to develop new effective treatments.

41 tosis congenita (DC), for which there are no effective treatments.

42 TNBC lacks effective treatments.

43 ting and, hence, there is an urgent need for effective treatments.

44 SARS-CoV-2), is a new human disease with few effective treatments(1).

45 rug that is slowly eliminated, might provide effective treatment and delay emergence of antimalarial

46 of prime importance as it paves the way for effective treatment and possible patient survival.

47 nderlie this neuropathy are not defined, and effective treatment and prevention measures are not avai

48 ctrocardiography (ECG) is the cornerstone of effective treatment and prevention of mortality; however

49 to adopt numerous changes, at least until an effective treatment and/or vaccine becomes widely availa

50 er is finding the balance between delivering effective treatments and avoiding adverse effects and fi

51 ease progression is important to design more effective treatments and therapies to alleviate DMD symp

52 d this death toll will be much higher before effective treatments and vaccines are available.

53 n intractable disease for which there are no effective treatments and which is characterized by a mer

54 mented when services for accurate diagnosis, effective treatment, and appropriate care can be offered

55 of unhealthy drug use or drug use disorders, effective treatment, and appropriate care can be offered

56 s for which services for accurate diagnosis, effective treatment, and appropriate care can be offered

57 rbidity, and prevalence of more than 2%, the effective treatment, and prevention of bipolar disorder

58 algorithms that emphasize early recognition, effective treatment, and team-based care of PCI complica

59 science, development of more acceptable and effective treatments, and implementation of public healt

60 mediated immunotherapy emerged as a safe and effective treatment approach for patients with advanced-

61 ruton tyrosine kinase (BTK) inhibition is an effective treatment approach for patients with Waldenstr

62 cision of the epileptogenic zone is the most effective treatment approach.

63 r novel therapeutic targets and develop more effective treatment approaches for related human disease

64 brain injury (TBI) and to identify the most effective treatment approaches for TBI.

65 innitus is likely accounting for the lack of effective treatment approaches.

66 is poorly understood resulting in a lack of effective treatment approaches.

67 Data on effective treatment are limited.

68 Few or no effective treatments are available for ageing-related ne

69 Few effective treatments are available for patients with met

70 py for head and neck cancer and for which no effective treatments are available.

71 ses have tripled over the past 20 years, but effective treatments are currently lacking.

72 LC) is an understudied cancer type for which effective treatments are currently unavailable.

73 ommon in non-small cell lung cancer (NSCLC), effective treatments are lacking.

74 transformative therapy for patients for whom effective treatments are lacking.

75 severe neuropsychiatric disorders, for which effective treatments are still elusive.

76 g of this heterogeneity is necessary if more effective treatments are to be developed.

77 r cause of blindness, and there is a lack of effective treatment at present.

78 Severe influenza infection has no effective treatment available.

79 The data have implications for expanding effective treatments available for HIV-infected individu

80 Surgery is the only effective treatment because mechanisms supporting tumor

81 cancer cell growth and function could be an effective treatment, but there are several challenges wh

82 from animal models can guide the search for effective treatments by ruling out those that lack effic

83 -1 entry via this mechanism.IMPORTANCE While effective treatment can lower the severe morbidity and m

84 Effective treatment can reverse tissue fibrosis in some

85 Despite effective treatment, chronic HIV infection disturbs MBCs

86 ential therapeutic options as the search for effective treatments continue.

87 ct children and young adults with no cure or effective treatment currently available.

88 The most effective treatment, dipping fillets into a sodium eryth

89 In the absence of an effective treatment, direct cell transplantation into th

90 The lack of effective treatments, disappointing results of many HF r

91 An effective treatment during the acute phase following SCI

92 Currently, no vaccine or effective treatment exists for RSV.

93 ting the CTLA-4 and PD-1 "checkpoints" is an effective treatment for a number of cancers.

94 HTx appears to be an effective treatment for a select group of muscular dystr

95 there is no unequivocal recommendation of an effective treatment for aceruloplasminaemia.

96 e receptor radionuclide therapy (PRRT) is an effective treatment for advanced gastroenteropancreatic

97 There is no effective treatment for AKI and new therapies are urgent

98 Gelatin fining proved to be a very effective treatment for astringency reduction, particula

99 gen receptor (CAR)-expressing T cells are an effective treatment for B-cell lymphoma, but often cause

100 gic Aurora B inhibition might be a potential effective treatment for breast cancer patients with meta

101 A gluten-free diet (GFD) is the only effective treatment for celiac patients and assessing ad

102 and remodeling, being a potentially new and effective treatment for chronic diabetic foot ulcers.

103 Currently, the only effective treatment for coeliac disease is a lifelong st

104 rovided convincing evidence that GCCNP is an effective treatment for DE and may represent a potential

105 ranscranial magnetic stimulation (TMS) is an effective treatment for depression but is limited in tha

106 Electroconvulsive therapy (ECT) is the most effective treatment for depression, yet its working mech

107 also suggest that modulating SURF4 may be an effective treatment for disorders of erythropoiesis that

108 beta2-adrenergic agonists are an effective treatment for DOK7-CMS.

109 s provide real-world support that DMEK is an effective treatment for FED with respect to vision resto

110 research using Fmr1 knock out (KO) mice, an effective treatment for FXS has yet to be developed.

111 Effective treatment for GO will modify one or more of th

112 Y90 is an effective treatment for HCC in the setting of bridging/d

113 There is no effective treatment for HTLV-1, and the osteolytic mecha

114 revlumab shows promise as a novel, safe, and effective treatment for idiopathic pulmonary fibrosis.

115 There is currently no cure or effective treatment for LAMA2-CMD.

116 lization (TACE) is an important yet variably effective treatment for management of hepatic malignanci

117 Surgical resection is the primary and most effective treatment for most patients with solid tumors.

118 in stimulation (DBS) has been shown to be an effective treatment for movement disorders and it is now

119 pletion via anti-CD20 antibodies is a highly effective treatment for multiple sclerosis (MS).

120 s, this novel nanoformulation of CCL21 is an effective treatment for neuroblastoma, and may have pote

121 reatments to manage pain and symptoms but no effective treatment for OA.

122 in rhesus monkeys, suggesting it could be an effective treatment for opioid use disorder (OUD).

123 TN) and globus pallidus internus (GPi) is an effective treatment for parkinsonian motor signs.

124 exone combined with behavioral therapy as an effective treatment for patients seeking opioid withdraw

125 AG10 has the potential to be a safe and effective treatment for patients with ATTR-CM.

126 ulking with power assisted liposuction is an effective treatment for patients with chronic extremity

127 PARP inhibition is an effective treatment for patients with MBC and gPALB2 or

128 gs indicate that CD229 CAR T cells may be an effective treatment for patients with MM.

129 bariatric surgery is well established as an effective treatment for patients with obesity and type 2

130 ng allogeneic islet transplant as a safe and effective treatment for patients with T1D and unstable g

131 d T cells targeting CD19 (CART19) provide an effective treatment for pediatric acute lymphoblastic le

132 f CB-839 with capecitabine could serve as an effective treatment for PIK3CA-mutant colorectal cancers

133 s suggest that acupuncture may be a safe and effective treatment for PMI and improving quality of sle

134 Pericardiectomy is a safe and effective treatment for posttransplant constrictive peri

135 pha2 chimeric antigen receptor T cells as an effective treatment for primary, metastatic and recurren

136 Ustekinumab is an effective treatment for psoriasis, but response varies b

137 Fingolimod is an effective treatment for relapsing-remitting multiple scl

138 Despite extensive investigations, an effective treatment for sepsis remains elusive and a bet

139 Effective treatment for severe asthma is a significant u

140 Electroconvulsive therapy (ECT) is an effective treatment for severe medication-resistant depr

141 Bariatric surgery is an effective treatment for severe obesity.

142 y (PRRT) using radiolabeled octreotate is an effective treatment for somatostatin receptor 2-expressi

143 adiotherapy using (177)Lu-DOTATATE is a most effective treatment for somatostatin receptor-expressing

144 The timely access to effective treatment for subfertility is important as man

145 dose reduction of ototoxic agents is a safe, effective treatment for these children.

146 though tyrosine kinase inhibitors provide an effective treatment for these diseases, they generally d

147 There is no effective treatment for this condition.

148 Bariatric surgery is the most effective treatment for weight loss.

149 Currently, the only effective treatments for a retained placenta are the sur

150 ng new pharmacotherapy for mania, developing effective treatments for acute bipolar depression remain

151 Further research is needed to identify effective treatments for acute heart failure in older pa

152 To date, there are no effective treatments for adRP.

153 ted that targeting GRPR and NPRA may provide effective treatments for allergic contact dermatitis-ass

154 Identifying effective treatments for Alzheimer's disease (AD) has pr

155 The lack of effective treatments for Alzheimer's disease (AD) is ala

156 In addition, effective treatments for chronic infections with both HB

157 Effective treatments for coronavirus disease 2019 (COVID

158 inical trials have been launched to identify effective treatments for COVID-19.

159 The search for more effective treatments for depression is a long-standing p

160 Despite the availability of effective treatments for depression, patients with co-oc

161 dogenous transport pathways may lead to more effective treatments for diseases within the reproductiv

162 ide mechanistic insights for developing more effective treatments for DMD.

163 l provide one of the last remaining safe and effective treatments for falciparum malaria that can be

164 There are now effective treatments for hepatitis B and hepatitis C, an

165 ave been largely unsuccessful in identifying effective treatments for HFpEF but evidence supports the

166 Unlike HFrEF, there are no effective treatments for HFpEF, which accounts for ~50%

167 pies improve outcomes in HFrEF, there are no effective treatments for HFpEF.

168 Thus, more effective treatments for major depression are needed, an

169 tive fields of study in the search for novel effective treatments for major depression.

170 Despite decades of research, effective treatments for most cancers remain elusive.

171 Globally, there is a huge unmet need for effective treatments for neurodegenerative diseases.

172 oid system that will help in developing more effective treatments for pain and addiction.

173 Effective treatments for patients with cholangiocarcinom

174 of these insights toward development of more effective treatments for patients with SR-aGVHD has at l

175 PA syndrome, it has been difficult to devise effective treatments for patients.

176 There are currently few approved effective treatments for SARS-CoV-2, the virus responsib

177 BACKGROUNDBariatric surgeries are the most effective treatments for successful and sustained weight

178 tments is low, and a need exists for further effective treatments for the condition.

179 Anti-TNF drugs are effective treatments for the management of Crohn's disea

180 he development of early diagnostic tools and effective treatments for these diseases.

181 ple sclerosis, and the recent development of effective treatments for these patients, there is a need

182 Multikinase inhibitors are effective treatments for thyroid cancers, acting primari

183 There is a clinically unmet need for effective treatments for triple-negative breast cancer (

184 Convenient, safe, and effective treatments for visceral leishmaniasis in Easte

185 are has become a critical part of developing effective treatment guidelines and improving patient out

186 Six months into the COVID-19 pandemic, effective treatments have been frustratingly sparse.

187 ch, no definite aetiological risk factors or effective treatments have been identified.

188 vasopeptidase inhibitors of NEP and ACE for effective treatment in hypertension and heart failure.

189 to medication regimens is a major barrier to effective treatment in many disease areas, notably in de

190 bout the disease but with no knowledge-based effective treatment in sight.

191 argets and conversion of this knowledge into effective treatments in humans.

192 the target for the development of innovative effective treatments in this disease.

193 Effective treatments include weight loss and exercise, p

194 The key for effective treatment is an accurate initial diagnosis at

195 no cure or established means of prevention, effective treatment is available.

196 of irreversible blindness worldwide, and no effective treatment is currently available.

197 Moreover, whereas an effective treatment is expected to achieve a rapid and s

198 clinic, but it remains unclear what the most effective treatment is.

199 Effective treatment largely abrogated cough aerosol cult

200 etter disease prognosis thus allowing a more effective treatment, lower associated morbidity, fewer f

201 In this comparative analysis, PDT was an effective treatment method for circumscribed choroidal h

202 ure model will pave the way to develop novel effective treatment modalities for CSOM beyond antibioti

203 r cell (HSPC) gene therapy has emerged as an effective treatment modality for monogenic disorders of

204 do not use any form of ST product, SRP is an effective treatment modality for the treatment of CP, an

205 orovirus enteritis, and it appeared to be an effective treatment modality.

206 The effective treatment of adenovirus (HAdV) infections in i

207 loped as a promising nanotherapeutic for the effective treatment of breast cancer and its lung metast

208 and may be a novel approach for the safe and effective treatment of breast cancer.

209 lid tumours remains a major challenge in the effective treatment of cancer.

210 w generation mTOR kinase inhibitors, for the effective treatment of cancers has not been achieved.

211 st that BMI1-specific inhibitors could be an effective treatment of CRPC.

212 Effective treatment of HIV infection has reduced the rat

213 illuminate a novel direction for developing effective treatment of irreversible dry mouth, which is

214 Spreading antimalarial resistance threatens effective treatment of malaria, an infectious disease ca

215 been identified as a major obstacle for the effective treatment of many cancers.

216 Effective treatment of obesity is necessary to reduce th

217 antages of BET/HDAC dual inhibitors for more effective treatment of pancreatic cancer.

218 d inhibition of oncogenic MYC expression for effective treatment of pancreatic cancer.

219 To still allow effective treatment of patients, rapid, automated, and r

220 f this novel formulation to deliver safe and effective treatment of prostate cancer is discussed.

221 Early detection and effective treatment of psychiatric and substance use dis

222 ancer therapy but needs improvement for more effective treatment of solid tumors.

223 ents a promising endeavour in the search for effective treatment of systemic autoimmune diseases.

224 ppear to provide a significant advantage for effective treatment of the gyrencephalic brain by system

225 as a new target in CAR-NK immunotherapy for effective treatment of TNBC and may warrant further prec

226 hydroartemisinin-piperaquine are both highly effective treatments of the blood stage infection.

227 actor (VEGF) therapy has been shown to be an effective treatment option for DME, although the injecti

228 -generated skin micropores offers a safe and effective treatment option for HDM-induced allergy and l

229 ourable benefit-risk profile and might be an effective treatment option for patients with active psor

230 In conclusion, DOACs are an effective treatment option for patients with cancer and

231 Deep brain stimulation (DBS) is an effective treatment option for patients with refractory

232 reas and kidney transplantation (SPKT) is an effective treatment option for patients with type 1 diab

233 a suggest that ruxolitinib cream might be an effective treatment option for patients with vitiligo.

234 ARP inhibitors with radiotherapy could be an effective treatment option for PFA ependymomas.

235 ic and bariatric surgery (MBS) is a safe and effective treatment option for severe obesity.

236 Meta-analysis supported pioglitazone as an effective treatment option for T2DM patients to ameliora

237 her indication of gene therapy as a possible effective treatment option for the neuropathic forms of

238 Revascularization was not a cost-effective treatment option from a payer/healthcare point

239 Cenobamate appears to be an effective treatment option in patients with uncontrolled

240 Closed-loop insulin delivery is an effective treatment option to improve glycaemic control

241 resection has been proposed as a potentially effective treatment option.

242 therefore a selective TLR8 agonist may be an effective treatment option.

243 ttention on liposuction, or debulking, as an effective treatment option.

244 Several effective treatment options are available for the most c

245 llular mechanisms involved in IVDD formation effective treatment options are still unavailable.

246 SVs) in cancer can lead to more targeted and effective treatment options as well as advance our basic

247 ful surgical treatment of locoregional PSCC, effective treatment options for advanced disease are lim

248 Both the auroKPro and the Boston Kpro are effective treatment options for patients with severe bil

249 ich ciprofloxacin and levofloxacin are fully effective treatment options for pneumonic plague in AGMs

250 ents in pharmacotherapy delivering the first effective treatment options for this condition.

251 ylene glycol) (PEG(400)) (P) might allow for effective treatment options in neuroblastoma.

252 d data support both VDZ and anti-TNFalpha as effective treatment options in UC and CD.

253 gents for the treatment of this disease, and effective treatment options remain very limited.

254 With the introduction of several effective treatment options, it is now even more importa

255 ious therapies for advanced disease have few effective treatment options.

256 eleterious neurodegenerative disease without effective treatment options.

257 most deadly brain tumor, and currently lacks effective treatment options.

258 accurate diagnoses, prevention measures, and effective treatment options.

259 with critical symptoms are in urgent need of effective treatment options.

260 However, no effective treatment or intervention strategies are avail

261 Currently, no effective treatment or prevention is available.

262 , as evidenced by the fact that there are no effective treatments or even an adequate understanding o

263 Currently, there are no fully effective treatments or vaccines available.

264 essential to improve the current marginally effective treatment outcomes.

265 nclude phase-based approaches, were the most effective treatment package for managing PTSD in complex

266 ents is critical for the development of more effective treatment paradigms.

267 a patient's tumor can inform the decision of effective treatment, regarding choices of chemotherapy,

268 and provide insights for the development of effective treatment regimens across PLK1-overexpressing

269 nse to anti-VEGF therapy and may enable more effective treatment regimens that improve anatomical out

270 , yet the mechanisms for their formation and effective treatments remain unknown.

271 ly devastating complication and consistently effective treatment remains elusive.

272 titis B and hepatitis C, and follow-up after effective treatment should be based on the use of the de

273 t into the inhibition of GBM progression and effective treatment strategies by targeting NRP-1 in add

274 More-effective treatment strategies still are needed for infa

275 T-resistant tumor types will help to develop effective treatment strategies.

276 y lead to more accurate drug design and more effective treatment strategies.

277 Pulmonary vein isolation (PVI) is an effective treatment strategy for patients with atrial fi

278 opoisomerase and PARP inhibitors might be an effective treatment strategy for this deadly disease.

279 CRT may be a highly effective treatment strategy in mrTD/mrEMVI positive pat

280 infection is often delayed past the point of effective treatment such that only the removal of the im

281 mportant if the disease-causing agent has no effective treatment, such as the novel coronavirus SARS-

282 on of CysLT receptor 1 is not a consistently effective treatment, suggesting additional regulatory me

283 rapeutically Applicable Research to Generate Effective Treatments (TARGET) initiatives, accounting fo

284 As a result, there is a critical need for effective treatment that attacks the aberrant kinome act

285 ease (AD) remains a complex disorder with no effective treatment that counteracts the memory deficits

286 progress in rehabilitative care, there is no effective treatment that stimulates axonal growth follow

287 This has hampered the design of effective treatments that could promise lifelong remissi

288 n of NF1 tumors and will be useful to define effective treatments that halt tumor growth and tumor pr

289 Vosoritide is an effective treatment to increase growth in children with

290 research over the last decades, there is no effective treatment to prevent or delay AD progression.

291 ilizumab might therefore be another safe and effective treatment to prevent relapses in patients with

292 There is a need, therefore, for more effective treatments to bolster the options available fo

293 to irreversible blindness, and there are no effective treatments to restore vision(1,2).

294 ging haplotypes of T. gondii and our lack of effective treatments to sterilize chronic infection.

295 The urgent need for an effective treatment together with a lack of small animal

296 al for early detection to improve chances of effective treatment where fundus cameras are used to cap

297 One stage LCBDE is a safe and cost effective treatment where the expertise and equipment ar

298 The effective treatment window and potential therapeutic mec

299 It offers an effective treatment with a high rate of complete respons

300 The most effective treatments, with highest cure rates, are also