ライフサイエンスコーパス: efflux

1 terol (a process referred to as "cholesterol efflux").

2 y, which could explain its altered substrate efflux.

3 ite-specifically impact the permeability and efflux.

4 which was found to be dependent on potassium efflux.

5 s little affected by porin modifications and efflux.

6 ophage functions including CFTR-mediated ion efflux.

7 t strongly decreased XPR1-mediated phosphate efflux.

8 whether ABCB1 is also involved in vitamin K efflux.

9 and is rescued by modulating CE synthesis or efflux.

10 that one of these chemicals induces rapid Mn efflux.

11 high internalized fraction, and low cellular efflux.

12 combination with increased free cholesterol efflux acceptors, has positive effects in mice by 1) red

13 teria, yeast, and plants by promoting Ca(2+) efflux across the cell membranes.

14 1) expression was reduced, and ABCC-mediated efflux activity was modulated by competition with nongly

15 ysis revealed that the 4R/A mutant had boron efflux activity, suggesting that the ScBOR1p monomer is

16 tributes to the suppression of FOXO1 nuclear efflux after IGF1.

17 pecific LAT-1 inhibitor), we showed that the efflux agonist did not inhibit the uptake of extracellul

18 PTIs, we serendipitously discovered a LAT-1 efflux agonist, which induces intracellular depletion of

19 creased MRP1 steady-state levels and fail to efflux an MRP1 substrate.

20 Finally, a vitamin K transintestinal efflux and a biliary vitamin K efflux were observed, but

21 KO of PPIP5Ks or XPR1 strongly reduced Pi efflux and accelerated differentiation to the mineraliza

22 This damage causes K(+) efflux and activation of NLRP3-dependent IL-1beta releas

23 PI1 invasion system), and, finally, chemical efflux and antibiotic tolerance (TolC efflux pump and Aa

24 nt regulator of cholesterol storage, uptake, efflux and biosynthesis, how these metabolic activities

25 They participate in multidrug efflux and cell wall biogenesis to transform bacterial p

26 P2RY1 activation triggers K(+) efflux and depolarization of hair cells, as well as osmo

27 ion of available C, greater overwinter CO(2) efflux and greater nutrient availability to plants at th

28 transporter A1 (ABCA1) and thus cholesterol efflux and increasing the abundance and modifying lipid

29 tionship between vitamin D and intestinal Mn efflux and indicate the importance of distal intestinal

30 MDAR on GABA interneurons to cause glutamate efflux and indirect activation of excitatory synapses.

31 t of the efflux pump, TolC, stimulating drug efflux and inducing expression of other efflux pumps.

32 namics depend on the spatial distribution of efflux and influx carriers on the cell membranes.

33 ata modify the auxin distribution created by efflux and influx carriers.

34 relationship between efficient microbial As efflux and its methylation, because the former prevents

35 rol also reduced ABCA1-dependent cholesterol efflux and LDL receptor activity in ORP1-null cells.

36 ose low in 12HBAs, induce cellular manganese efflux and that Slc30a10 induction by BA pools is driven

37 I via 5-OHTrp at Trp(72) impairs cholesterol efflux and the rate-limiting step of HDL biogenesis both

38 novel sugar transporter for Suc and glucose efflux and unloading.

39 drug or gene candidates that affect uptake, efflux, and metabolism of this important cofactor.

40 -N, corresponding to a 33% decrease in CO(2) efflux, and reductions in relative abundances of bacteri

41 activation of purinergic autoreceptors, K(+) efflux, and subsequent depolarization of inner hair cell

42 t their cellular permeability is governed by efflux, as reported in the Caco-2 assay.

43 Nile Red efflux assays and RT-qPCR analysis suggest ospemifene in

44 ic resonance (SSNMR) spectroscopy, potassium efflux assays, and Forster resonance energy transfer (FR

45 DeltaPsi; 2) DeltaPsi increases the rate of efflux at all tested pH values, but enhancement is almos

46 of ispinesib is restricted by P-gp and Bcrp efflux at BBB.

47 y mediator of multidrug resistance, the drug efflux behavior of P-glycoprotein (P-gp) remains a promi

48 yielding the observed patterns of soil CO(2) efflux being out of sync with soil temperature.

49 , presumably through their efficient As(III) efflux, but methylated As poorly.

50 rt study, compound 12 stimulated cholesterol efflux by 53% demonstrating HDL-C functionality.

51 cate that chemical proton gradient-dependent efflux by LmrP in cells converts populations of highly f

52 y, high first-pass metabolism, and efficient efflux by P-glycoprotein.

53 APP promotes neuronal iron efflux by stabilizing the cell-surface presentation of f

54 athione adducts are recognized and, in turn, effluxed by ABCC1.

55 y established that androgen glucuronides are effluxed by multidrug resistance-associated proteins 2 a

56 The ABCA1-specific cellular cholesterol efflux capacity (ABCA1 CEC) of HDL strongly and negative

57 Low values of cholesterol efflux capacity (OR(1SD), 0.33; 95% CI, 0.18-0.61), sphi

58 Low values of cholesterol efflux capacity (OR(1SD), 0.58; 95% CI, 0.40-0.83) and l

59 xert a synergistic effect on HDL cholesterol efflux capacity in the familial hypercholesterolemia pla

60 Cholesterol efflux capacity increased in the whole-egg treatment (me

61 Low cholesterol efflux capacity values, pro-oxidant/proinflammatory HDL

62 nt with inflammatory remodeling, cholesterol efflux capacity was reduced by 32% (P<0.001) at both tim

63 rotein composition and function (cholesterol efflux capacity) in patients after acute ischemic stroke

64 inhibition, coupled to increased cholesterol efflux capacity, favorably remodels atherosclerosis lesi

65 particles and facilitating their cholesterol efflux capacity.

66 terol concentration (in plasma); cholesterol efflux capacity; antioxidant ability, measured by the HD

67 racterized a wheat (Triticum aestivum) auxin efflux carrier ABCB1.

68 script abundance of MdPIN1 encoding an auxin efflux carrier but a higher transcript abundance of MdGH

69 of polarly localized PIN-FORMED (PIN) auxin-efflux carriers.(1-4) In particular, the timing of this

70 lcium dynamics through the lysosomal calcium efflux channel, transient receptor potential mucolipin 1

71 (Mdr) transporter MdfA from Escherichia coli efflux chemically- dissimilar substrates in exchange for

72 tion efficiency and ability of T1317-sHDL to efflux cholesterol.

73 HDL subsequently delivers effluxed cholesterol to the liver by the process of reve

74 nd fractions in brain, permeability, and low efflux culminated in the discovery of compound 1, which

75 acterial activities of the compounds against efflux-deficient Escherichia coli are mediated by LpxA i

76 Glycolytic efflux doubled with 25 mm [U-(13)C(6)]glucose; however,

77 general and inducible mechanism of electron efflux during normal bacterial proliferation leads to a

78 pression and a lack of increase in glutamate efflux during reinstatement of cocaine-seeking.

79 substance-metal complexes and a small active efflux during the night with adsorption and incorporatio

80 calcium channel TRPML1, facilitating calcium efflux essential for TFEB activation.

81 influenced by poorly constrained soil CO(2) efflux (F(soil)).

82 ound that Chow/Palatable rats had blunted DA efflux following d-Amphetamine treatment.

83 +)/Ca(2+) exchanger (I(NCX))-mediated Ca(2+) efflux from cytosol, thereby reducing EADs.

84 hat streptolysin O (SLO)-induced glutathione efflux from host cellular stores is a previously unappre

85 ystinosin, a symporter that mediates cystine efflux from lysosomes.

86 17-sHDL exhibited more efficient cholesterol efflux from macrophages and enhanced atheroma-targeting

87 mass may have offset roughly half the carbon efflux from peat oxidation.

88 Attenuated Pi efflux from PPIP5K KO cells was quantitatively phenocopi

89 Moreover, Pi efflux from PPIP5K KO cells was rescued by restoration o

90 nt role of uptake compared to desorption and efflux from the biofilm.

91 c accumulation of the contrast agent and its efflux from the cells, most of these imaging methods ina

92 Q3: Does malate efflux from the vacuole set the pace of decarboxylation?

93 afferent membrane potentials; the potassium efflux from type I hair cells results from the interdepe

94 human glioblastoma multiforme, blocking the efflux function of P-gp with verapamil enhanced the ther

95 Similar to the efflux function of wild-type P-gp, we found that uptake

96 ) are transporters with phosphate uptake and efflux functions, respectively.

97 ponsible for mitochondrial Ca(2+) uptake and efflux have been identified.

98 Although mitochondrial Ca(2+) uptake and efflux have been studied for over 50 years, it is only i

99 g/tg)) mice, which have elevated cholesterol-effluxing high-density lipoprotein particles, and subjec

100 Moreover, blocking of potassium efflux improved the mitochondrial health in addition to

101 at ABCB1 is involved in enterocyte vitamin K efflux in both cell and mouse models and regulates vitam

102 Potent inhibition of P-gp efflux in cells, including human brain endothelial cells

103 Azoffluxin also inhibits efflux in highly azole-resistant strains of Candida albi

104 Many studies of cholesterol efflux in macrophages have focused on the role of ABC tr

105 ux; 3) mutant Glu325 - Ala does little or no efflux in the absence or presence of DeltaPsi, and ambie

106 he glutamate transporter GLT-1 and glutamate efflux in the nucleus accumbens (NA) core during the rei

107 Girdling birches reduced total soil CO(2) efflux in the peak growing season by 53%, which is doubl

108 willow shrubs contributed 38% to soil CO(2) efflux in their patches.

109 gamma expression and apolipoprotein E (ApoE) efflux in these cells with an efficacy that was comparab

110 osomes cross the BBB in vivo using the brain efflux-index method.

111 Macrophage cholesterol efflux induced in vitro by LDL added to the culture medi

112 DeltaPsi (interior positive) on the K(m) for efflux is almost insignificant relative to the 50- to 10

113 ntemporary carbon uptake, given that methane efflux is fueled primarily by fresh carbon inputs.

114 Cellular Pi efflux is heavily reliant on Xenotropic and Polytropic R

115 Foxo1 nuclear efflux is promoted by AKT-mediated Foxo1 phosphorylation

116 Chloride efflux is suggested as an important step in NLRP3 activa

117 hich remain poorly understood for soil CO(2) efflux, J(CO2), a primary carbon flux from the biosphere

118 elimination pathways and utilizing different efflux kinetics of medical agents in normal and diseased

119 vation of cholesterol biogenesis, import and efflux, leading to increased serum and faecal cholestero

120 tivation of NLRP3 inflammasomes through K(+) efflux, leading to the recruitment of ASC and activation

121 vious atropisomerism, solubility, and Caco-2 efflux liabilities.

122 (HDLs), but other mechanisms for cholesterol efflux likely exist.

123 etrate the outer-membrane or are excluded by efflux mechanisms.

124 e that cross-linking impairs the cholesterol efflux mediated by apoA-I or HDL3 in vitro and in vivo U

125 y inspire therapeutic development to preempt efflux-mediated antimicrobial resistance.

126 P3 inflammasome by preventing potassium (K+) efflux, mitochondrial ROS (mtROS) generation, and, ultim

127 ction could be balanced, maintaining low Pgp efflux needed for CNS penetration.

128 Transcriptomic studies with RND efflux-negative V. cholerae suggested that RND-mediated

129 These enhanced DOC effluxes occurred at a scale that decreases estimates fo

130 e beginning of 2011, while a substantial net efflux of >600 g C/m(2) occurred over a 2 month period i

131 o FAP, cellular uptake, internalization, and efflux of [(18)F]FGlc-FAPI in vitro.

132 ers belong to the ABC family and mediate the efflux of a sterol substrate, they have many distinct di

133 in liver and kidneys, mediates the cellular efflux of ATP, which is rapidly converted into inorganic

134 in increased glycosphingolipid synthesis and efflux of Cav-1-sphingolipid particles containing mitoch

135 cell membrane transporter that mediates the efflux of chemically dissimilar amphipathic drugs and co

136 n of ROR1 directly correlated with decreased efflux of chemo-drugs from cells.

137 ing cassette member involved in the cellular efflux of chemotherapeutic drugs.

138 holesterol transport pathway and mediate the efflux of cholesterol and xenosterols to high-density li

139 on atheroma macrophages leading to increased efflux of cholesterol to endogenous high-density lipopro

140 a two-pore channels, accompanied by parallel efflux of Cl(-) and osmotically coupled water.

141 ive nuclear ruptures, which promoted nuclear efflux of E4orf4 and loss of nuclear integrity.

142 ition of ABCC-mediated transport reduced the efflux of exogenous C(6)-ceramide.

143 nd pyrrolidine dithiocarbamate (PDTC) on the efflux of GSH and Cys from HepG2 cells.

144 At longer times, substantial efflux of H2O2 from the mitochondria to the cytosol was

145 Neglecting efflux of H2O2 to the cytosol, the mitochondrial reactio

146 the cytoplasm and perhaps importantly lower efflux of HgII by the cells, thus the "net" accumulation

147 pe of cell death, dose-dependent uptake, and efflux of inorganic HgII (as HgCl(2)) and methylmercury

148 the remarkable observation was made that an efflux of intracellular inorganic phosphate (P(i)) accom

149 cellular leucine but instead facilitated the efflux of intracellular leucine pools.

150 ns involved in the acquisition, storage, and efflux of iron accordingly.

151 Efflux of K(+) through G(BK) can rapidly elevate [K(+) ]

152 er, LXR target gene products facilitated the efflux of lipid and cholesterol from lipid-laden microgl

153 ch likely result in less uptake or increased efflux of m-Tyr.

154 mily of membrane proteins, and modulates the efflux of many drugs at the cell membrane, resulting in

155 How the protein shell directs influx and efflux of molecules in an effective manner has remained

156 ncluding non-uniform permeability and active efflux of molecules.

157 l(-)) channels, which mediate the influx and efflux of monovalent anions in response to the levels of

158 nounced in MDR cells due to the Pgp-mediated efflux of NSC297366-iron complexes.

159 analyses demonstrated capillary leakage with efflux of nutrients and antioxidants into the alveolar s

160 tripartite lytic pore that is permissive to efflux of potassium.

161 We show enhanced efflux of preexisting carbon from intertidal sediments e

162 LDL induced the efflux of radiolabeled UC from cultured macrophages, and

163 cellular ion channels that results in a net efflux of salt and water into the intestinal lumen, culm

164 ation activity is only maintained through an efflux of succinate.

165 12 transporter, pmp-5, and adjust influx and efflux of the cycle by activating msra-1 and repressing

166 C-phages during infection could modulate the efflux of this potent greenhouse gas into the environmen

167 We demonstrate that cGAMP is effluxed or influxed via LRRC8 channels, as dictated by

168 pathway enables ICG-PEG45 to be effectively effluxed out of normal proximal tubules through P-glycop

169 h the proteobacterial antimicrobial compound efflux (PACE) family.

170 , are important mediators of cellular Ca(2+) efflux, particularly in neurons associated with sensory

171 Renal tubular secretion is an active efflux pathway for the kidneys to remove molecules but h

172 onformation and completely occludes the iron efflux pathway to inhibit transport.

173 in the genes related to mitochondrial Ca(2+) efflux pathways, suggesting a counteracting effect to av

174 - or insulin-induced effect on FOXO1 nuclear efflux, phosphatidylinositol 3-kinase inhibitors, which

175 is family, AceI (Acinetobacter chlorhexidine efflux protein I), is encoded for by the aceI gene and i

176 control of AceR (Acinetobacter chlorhexidine efflux protein regulator), a LysR-type transcriptional r

177 s, MGMT (a DNA repair protein) and ABCB1 (an efflux protein), revealing microRNA-4539 and microRNA-42

178 ecific gene Ferroportin2 (MtFPN2) is an iron-efflux protein.

179 jacent endothelial cells and the presence of efflux proteins prevents entry of foreign substances int

180 y anti-cancer therapeutics or trans-membrane efflux proteins that pump anti-cancer therapeutics out o

181 6-dimethoxyphenol against the S. aureus NorA efflux pump (EP) in association with norfloxacin and eth

182 The drug efflux pump ABCB1 is a key driver of chemoresistance, an

183 Drug efflux pump ABCB1 is overexpressed in chemoresistant neo

184 istic action of outer membrane permeability, efflux pump activities and enzymatic degradation efficie

185 emical efflux and antibiotic tolerance (TolC efflux pump and AadA aminoglycoside 3-adenyltransferase)

186 g export and inhibition of a major multidrug efflux pump and the directive role of its dynamics.

187 uconazole activity through the inhibition of efflux pump Cdr1, thus increasing intracellular fluconaz

188 Although previous work claimed that this efflux pump extrudes the QS signal 3-oxo-C12-HSL, we sho

189 These results show that SmvA is a major efflux pump for cationic biocides in several bacterial s

190 Deletion of an efflux pump gene (acr3) in one of the anaerobes, Clostri

191 The antibiotic efflux pump genes, mef(A) and msr(D), were present on ch

192 nce-1 (MDR1) acts as a chemotherapeutic drug efflux pump in tumor cells, although its physiological f

193 We show that an efflux pump inhibitor potentiates antibiotic activity by

194 llows for the design and optimization of new efflux pump inhibitors to more effectively treat infecti

195 he inhibitory effect of progesterone and the efflux pump inhibitors verapamil and 1-(1-naphthylmethyl

196 s; (ii) outer membrane permeabilizers; (iii) efflux pump inhibitors.

197 tify loss-of-function (LOF) mutations in the efflux pump mtrCDE operon as a mechanism of increased an

198 revealed that either BC target mutations or efflux pump overexpression can lead to the development o

199 ent antibiotic resistance mechanisms: 1) the efflux pump protein TolC and 2) the structural barrier m

200 acterial outer-membrane, it also deactivates efflux pump systems by dissipating the transmembrane ele

201 well as expression of MDR1, which encodes an efflux pump that exports fluconazole.

202 a component of a multidrug resistance (MDR) efflux pump were concluded to be essential for the patho

203 ment holds true for LOF mutations in another efflux pump, farAB, and in urogenitally-adapted versus t

204 esistance due to increased expression of the efflux pump, MexXY.

205 We find that a single efflux pump, norA, causes widespread variation in evolva

206 ells with an outer membrane component of the efflux pump, TolC, stimulating drug efflux and inducing

207 ctive form of irinotecan/CPT-11) to overcome efflux pump-driven drug resistance was tested.

208 rug development in strains carrying the NorA efflux pump.

209 ompounds with the binding pocket of the NorA efflux pump.

210 h impairment are different for each analysed efflux pump.

211 ABCC1, and COTI-2 being a substrate for this efflux pump.

212 the emhABC operon encoding a major multidrug efflux pump.

213 majority mapped to the fragment of aflatoxin efflux-pump gene.

214 We identified additional efflux pumps and transcriptional regulators that contrib

215 Multidrug (MDR) efflux pumps are ancient and conserved molecular machine

216 although the consequences of overexpressing efflux pumps are similar (impaired QS response), the und

217 olved structures of bacterial inner membrane efflux pumps as to how they bind and transport their sub

218 nce-nodulation-division (RND) type multidrug efflux pumps have been demonstrated to convey antibiotic

219 yl)-piperazine is consistent with a role for efflux pumps in preventing progesterone-mediated inhibit

220 oss the outer membrane and active efflux via efflux pumps in the inner membrane creates a permeabilit

221 been shown that overexpression of different efflux pumps is linked to the impairment of the quorum s

222 tic resistance in this species is enabled by efflux pumps of the Resistance-Nodulation-Division (RND)

223 cally conferred by proteins that function as efflux pumps or enzymes that modify either the drug or t

224 Resistance-nodulation-division efflux pumps play a key role in inherent and evolved mul

225 Multidrug efflux pumps present a challenge to the treatment of bac

226 drug resistance is through the expression of efflux pumps that actively pump drugs out of the cells.

227 ABC) transporters represent a large group of efflux pumps that are strongly involved in the pharmacok

228 of ethidium bromide (a substrate for several efflux pumps) or norfloxacin was used as a parameter of

229 It uses multidrug efflux pumps, including the MexAB-OprM pump, for antibio

230 eatments, attributed in part to mutations in efflux pumps, is rapidly emerging.

231 minantly by inducible Mef(A) and Msr(D) drug efflux pumps.

232 tify as AcrA, a periplasmic component of RND efflux pumps.

233 drug efflux and inducing expression of other efflux pumps.

234 during every year of measurement with annual efflux ranging from 183 to 632 g C m(-2) year(-1) , noti

235 The efflux rate of lactate-CH(3), lactate-CH(2)D and lactate

236 based on the following observations: 1) the efflux rate of WT LacY exhibits a pK(app) of ~7.2 that i

237 treatment abolished XPR1-mediated phosphate efflux regulation and homeostasis.

238 s including upregulation of C. albicans drug-efflux, regulation of oxidative stress response, and mai

239 actable structure-permeability and structure-efflux relationships, wherein the linker length, stereoi

240 stems, but vegetation controls on soil CO(2) efflux remain poorly resolved.

241 sal ATP levels were restored after phosphate efflux rescue with WT XPR1 but not with XPR1 harboring a

242 In this report, we investigated six RND efflux-responsive regulatory genes for contributions to

243 was required for homeostasis, as loss of RND efflux resulted in the activation of transcriptional reg

244 trols cellular phosphate homeostasis via the efflux route, and alteration of this interplay likely co

245 transporters, whereas EcLsi2 and EcLsi3, an efflux Si transporter, belong to an uncharacterized anio

246 facilitate export by the Cus RND transporter efflux system.

247 RND efflux systems are often associated with multiple antimi

248 Multidrug efflux systems belonging to the resistance-nodulation-di

249 This 'apparent redundancy' of MDR efflux systems can be understood as a P. aeruginosa stra

250 segregation, cell division, GABA metabolism, efflux systems, and stress tolerance play an important r

251 t ospemifene interferes directly with fungal efflux systems, thus permitting entry of azole drugs int

252 which are substrates of the V. cholerae RND efflux systems.

253 r sampling was used to explore rates of H2O2 efflux that could reconcile model predictions of Prx3 ox

254 several bacterial species and that increased efflux through SmvA can lead to increased chlorhexidine

255 ophages require LXRalphabeta for cholesterol efflux, thymic epithelial cells (TECs) use LXRalphabeta

256 ediate the activity-dependent control of BBB efflux transport.

257 nd high membrane permeability, and is not an efflux transporter (P-gp) substrate.

258 ced the surface abundance of the cholesterol efflux transporter ABCA1, which in turn promoted lipid a

259 ycoprotein (P-gp) was identified as the main efflux transporter across the BBB, in vivo and in vitro.

260 SLC30A10 is a manganese efflux transporter critical for whole-body manganese exc

261 particular, neuronal activity regulates BBB efflux transporter expression and function, which is cri

262 e action of the hormone hepcidin on the iron efflux transporter ferroportin.

263 stimulated the expression of Si channel and efflux transporter genes- Lsi1 and Lsi2 while the additi

264 forming P-gp or an ABC drug exporter from an efflux transporter into a drug uptake pump would constit

265 ding cassette transporter P-glycoprotein, an efflux transporter known to detoxify taxol, were found t

266 rcome the BBB, both passive permeability and efflux transporter liability of a compound must be addre

267 ABCB1 (P-glycoprotein/MDR1) is a multidrug efflux transporter that has previously been involved in

268 An efflux transporter, ABCG2, was lower, while mRNAs encodi

269 In addition, Slc30a10, encoding a manganese efflux transporter, was one of the genes most induced by

270 lin-resistant S. aureus strains that express efflux transporters such as NorC in hospital and communi

271 review, we summarize the RND superfamily of efflux transporters with a primary focus on the assembly

272 temness signaling pathways, surface markers, efflux transporters, or components of complex tumor micr

273 s that are often protected from treatment by efflux transporters, such as P-glycoprotein (P-gp) at th

274 pressed in chemoresistant neoplasms where it effluxes various chemotherapeutic agents from cells.

275 uptake across the outer membrane and active efflux via efflux pumps in the inner membrane creates a

276 arnessed by an anionophore to drive chloride efflux via H(+)/Cl(-) cotransport.

277 NKCC1 ionic influx and inhibits KCC-mediated efflux via phosphorylation at conserved, shared motifs.

278 bsorption during MAlk by opposing HCO(3) (-) efflux via the basolateral anion exchanger AE2; and (3)

279 eaf for photosynthesis and restricting water efflux via transpiration.

280 Pi efflux was also rescued in a dose-dependent manner by li

281 t of the imposed DeltaPsi on the kinetics of efflux was also studied in right-side-out membrane vesic

282 d selectivity while minimizing P-gp mediated efflux was fine-tuning of hydrogen bond acceptor basicit

283 XPR1-mediated Pi efflux was inhibited by reducing cellular InsP(8) synthe

284 s was significantly higher and extracellular efflux was lower in the presence than in the absence of

285 ompounds, the GA-induced restoration of ApoE efflux was not affected by pharmacological inhibition of

286 tive V. cholerae suggested that RND-mediated efflux was required for homeostasis, as loss of RND effl

287 Vitamin K apical efflux was significantly decreased in presence of ABCB1

288 In keeping with other cell types, basal P(i) efflux was stimulated by inositol pyrophosphates, and ba

289 egative connexin 43 or by disrupting lactate efflux was sufficient to mimic the effects of stress on

290 liver X receptors in stimulating cholesterol efflux, we demonstrate that liver X receptors are necess

291 tive method to monitor lysosomal cholesterol efflux, we found that NPC1's N-terminal domain need not

292 In this study, rates of lactose/H(+) efflux were measured from pH 5.0 to 9.0 in the absence o

293 ansintestinal efflux and a biliary vitamin K efflux were observed, but the specific involvement of AB

294 Methane effluxes were higher in fire-affected areas (7.8 +/- 2.2

295 gulators of cholesterol homeostasis, driving efflux when cholesterol levels are high and facilitating

296 d, but also unexpectedly increased phosphate efflux, whereas PFBC-associated SLC20A2 variants did not

297 to glucolipotoxicity inhibiting autolysosome efflux, which in turn intensifies Nrf2-driven transcript

298 ortex (mPFC) without any effect on glutamate efflux, while ketamine blocks NMDAR on GABA interneurons

299 to meteorology, and we estimated soil CO(2) efflux with a gradient-flux model.

300 cts of IGF1 and insulin on FOXO1-GFP nuclear efflux with and without pharmacological inhibitors.