ライフサイエンスコーパス: effort

1 lbeit in minute quantities and with enormous effort.

2 inoma (PDAC) remains poor despite decades of effort.

3 d as a critical challenge to any elimination effort.

4 f willpower, or how motivation is related to effort.

5 ased on this large-scale targeted sequencing effort.

6 group and consequently prioritized by relief efforts.

7 t but are not apparent with current sampling efforts.

8 rioritization of PCR testing and containment efforts.

9 ing, treatment, and public health prevention efforts.

10 ganelles and will aid downstream engineering efforts.

11 ndwork to streamline future drug development efforts.

12 n two reproducible somatic variant detection efforts.

13 inclusion of resources in metabolic scaling efforts.

14 er's disease remain despite intense research efforts.

15 organizations that wish to strengthen their efforts.

16 riod could contribute to malaria elimination efforts.

17 e possible through large-scale collaborative efforts.

18 future directions to continue implementation efforts.

19 d be used to help to prioritize conservation efforts.

20 tion help guide policy surrounding reopening efforts.

21 sparing costly and time-consuming synthesis efforts.

22 only) expand the role SAARs can play in ASP efforts.

23 pathways limits the effectiveness of control efforts.

24 be cost-saving compared with current control efforts.

25 lement pro-inclusion and diversity-enhancing efforts.

26 ous disease impacts and hampers conservation efforts.

27 across the human body is important for cure efforts.

28 hamper epidemic control or patient treatment efforts.

29 nts deriving from this aspect of my research efforts.

30 nship, limiting the success of translational efforts.

31 hospital cardiac arrest (OHCA) resuscitative efforts.

32 xposure has been a major focus of prevention efforts.

33 sess the potential success of local response efforts.

34 system to prioritize antibiotic stewardship efforts.

35 ich can substantially advance drug discovery efforts.

36 spite some successful cases and conservation efforts, 21.4% of China's vertebrate species are threate

37 The comparison of cognitive effort against other primary aversive experiences, howev

38 Ongoing efforts aim to integrate our understanding of HNSCC biol

39 Our findings may help efforts aimed at generating salt-tolerant crops.

40 atalog could inform ongoing drug development efforts aimed at intercepting and treating coronavirus d

41 Past and current efforts aiming to enhance workforce diversity but target

42 ance distinctly alters implicit and explicit effort allocation as a function of instantaneous reward.

43 Such efforts, although critically important, are locally cons

44 mplex vocalizations can require considerable effort and a deep intuition about each species' vocal be

45 human annotation requires considerable time, effort and expertise.

46 ecision times revealed asymmetric effects of effort and pain, suggesting that cognitive effort may no

47 al data or standard single-gene surveillance efforts and also revealed connections between apparently

48 ys that are not designed to assess inclusion efforts and consequences.

49 arch investment through global collaborative efforts and partnerships.

50 rmore provide a detailed outlook over future efforts and promising new avenues in this field.

51 contributed directly to Utah's biomaterials efforts and the Total Artificial Heart program at the ti

52 This article describes the efforts and vision of the multistakeholder Prior Authori

53 Subjective ratings, physical effort, and facial reactions to matched primary social (

54 Future water levels without any mitigation efforts are anticipated to decline by up to 2.8 m/year i

55 Great efforts are being made worldwide to identify the specifi

56 Enhanced vaccination efforts are critically needed, particularly targeting ad

57 Therefore, extensive efforts are devoted to the development of protease senso

58 Modern genomic sequencing efforts are identifying potential diagnostic and therape

59 e areas where urgent biodiversity monitoring efforts are needed to develop more accurate knowledge on

60 Concerted efforts are needed to reduce health inequalities that ar

61 Herein, efforts are presented for preparing and forming cellulos

62 These efforts are propelled by advances in single cell profili

63 tial is crucial to ensure food security, but efforts are thwarted by an apparent trade-off between gr

64 Tremendous research and commercialization efforts around the world are focused on developing novel

65 Many researchers at the time viewed this effort as folly.

66 as been the focus of numerous drug discovery efforts as this is the target of the first line pro-drug

67 gagement during language processing reflects effort associated with extraneous task demands.SIGNIFICA

68 During 2018, we initiated a focused effort at vSNF-A and conducted 7 C. auris PPSs; during 4

69 erstones of global biodiversity conservation efforts, but to fulfil this role they must be effective

70 ce spurred decades of waterfowl surveillance efforts by researchers dedicated to understanding the ec

71 nides (TMDs) have triggered intense research efforts by the scientific community.

72 ure, but this is likely to change as current efforts come to fruition.

73 oyed residents elsewhere to support COVID-19 efforts.CONCLUSIONMany resident physicians around NYC ha

74 In this context, many of Sung Wan's early efforts contributed directly to Utah's biomaterials effo

75 also coincided with decreased catch per unit effort (CPUE) and species density per unit effort (SDPUE

76 rfishing landings, commercial catch per unit effort (CPUE), and lionfish tournament CPUE also decline

77 These efforts demonstrate how machine learning can be used to

78 o far largely been driven by trial and error efforts due to a critical lack of methods to probe their

79 n by NIV was linearly related to inspiratory effort during HFNC (r = 0.84; P < 0.001).

80 Maximal reproductive effort early in life is predicted to be maladaptive by a

81 easures (sway, acceleration, co-contraction, effort, falls) showed no correlation with either FAC or

82 Multifaceted efforts focusing on all three types of overuse and multi

83 k ATR inhibitory activity, lead optimization efforts focusing on potency, selectivity, and oral bioav

84 Here, male rats were trained to exert effort for a high-value reward (sucrose pellets) in a pr

85 Despite efforts for beta-C-H functionalization in carbon-carbon

86 Global efforts for biodiversity protection and land use-based g

87 ize recent relevant research contributing to efforts for developing nanopore methods associated with

88 s et al. discuss the results of conservation efforts for mangrove forests in recent years.

89 team to integrate with software development efforts for resistome analysis and prediction, such as C

90 eimer's disease, has driven many therapeutic efforts for the past 20 years.

91 This document represents an effort from editors at 31 respiratory, sleep, and critic

92 With intensive efforts from many prominent research groups, it becomes

93 Combined efforts from many theoretical and experimental studies o

94 This opens the door for efforts from the research community to update the nomenc

95 the toxicity issue, intense recent research effort has been devoted to developing lead-free halide p

96 n adipose tissue (BAT) in adult humans, much effort has been devoted to exploring this tissue as a me

97 Since their discovery in 2007(1), much effort has been devoted to uncovering the sources of the

98 Recently, a lot of effort has been put into identifying compounds that sele

99 Although most effort has focused on generating pancreatic beta cells,

100 ce and adaptive evolution, relatively little effort has focused on how it influences the evolution of

101 Over the last decades, great effort has gone into developing new biosensor technologi

102 A key focus of these efforts has been on a class of drugs called histone deac

103 A recent wave of synthetic biology efforts has focused on the establishment of molecular bi

104 ver, the relevant characteristics of such an effort have been uncertain.

105 Although extensive efforts have been dedicated to developing catalysts for

106 Consequently, in recent years research efforts have been directed towards modeling the structur

107 Numerous efforts have been made to circumvent the need for immuno

108 r pressures almost a century ago(2), several efforts have been made to explain the many unusual prope

109 Efforts have been made to reduce THM levels in the Europ

110 Second, efforts have been made to understand "what" the dorsolat

111 Significant efforts have been recently made to obtain the three-dime

112 own capabilities and limitations, and major efforts have broadened their editing capabilities, expan

113 Nonetheless, in recent years considerable efforts have ensued to characterize alternative electrop

114 Our structure-based efforts have identified promising leads to be developed

115 Large-scale sequencing efforts have led to the classification of melanoma into

116 Past efforts have not considered evoking long-term changes in

117 These efforts have provided insights into the circuits and int

118 These efforts have provided pivotal new insights into the dive

119 Intensive global research efforts have therefore persistently focused on bleaching

120 ove wild pigs averaged $50 per wild pig (6.8 effort hours per wild pig) for removing the first 99% of

121 ential addition to Ebola vaccine development efforts.IMPORTANCE Ebola outbreaks result in significant

122 o not require laboratory monitoring, greater effort in monitoring for and interventions to prevent no

123 of hybridization like waste of reproductive effort in small isolated populations may be more problem

124 This advocates for coordinated public health efforts in addition to local targeted interventions.IMPO

125 In spite of the efforts in developing and maintaining accurate variant d

126 anding of the mind's structure requires more efforts in developing cognitive architectures.

127 We conclude that global long-term greening efforts in drylands require careful ecohydrologic evalua

128 Since cures are currently unavailable, major efforts in improving brain health need to focus on preve

129 This review emphasizes recent research efforts in order to elucidate the next steps needed to d

130 Diverse efforts in protein engineering are beginning to produce

131 of a structural approach to inform clinical efforts in targeting KRAS-G12D tumors by immunotherapy a

132 dE provides also a starting point for future efforts in the development of anti-TB drugs.

133 l promoters and facilitate synthetic biology efforts in this model organism.

134 nd a large-scale international collaborative effort, including data for 563,085 European ancestry par

135 However, in recent trials and implementation efforts, interventions to improve HAP and WASH condition

136 ulting in improved outcomes, will reward the effort invested in incorporating sex as a biological var

137 Cognitive effort is described as aversive, and people will general

138 While the driving force for the effort is in the realm of nuclear nonproliferation effor

139 At the forefront of this effort is the modulation of autoantibody half-life and b

140 The central idea of this joint effort is to highlight key parameters and pitfalls that

141 timing, intensity, and frequency of control efforts is critical to the management of biological inva

142 g from being used routinely in public health efforts; it is fast, robust, and cost-efficient, and gen

143 In this effort, machine learning (ML) is applied in a systematic

144 Current efforts mainly focus on surface modification to suppress

145 moval, yet remains under paced in deployment efforts, mainly because of high costs.

146 f effort and pain, suggesting that cognitive effort may not share the same basic influences on avoida

147 sparities suggest that greater public health efforts may be needed to mobilize the most vulnerable co

148 cluding the nations of Central Africa, where efforts may necessitate establishing rapid conservation

149 the way to more precise treatment, but more efforts need to be devoted to a better understanding of

150 Efforts need to be made to increase the perception, use,

151 an extraordinary international collaborative effort of independent researchers who have recently all

152 each of these papers is a distinct creative effort of its authors, I would like to draw your attenti

153 SARS-CoV-2 control requires the synergistic efforts of case isolation, contact quarantine, and popul

154 The rapid spread of COVID-19 has focused the efforts of scientists on repurposing existing Food and D

155 Our analysis supports an urgent effort on the part of Brazilian authorities to consider

156 lar phosphorylation state; surprising little effort on this topic has been expended in computational

157 Through integrated efforts on both sensor device innovation and machine lea

158 Chemistry efforts on the scaffold revealed a dynamic structure act

159 ver, use of a public health approach focuses efforts on those impacted by exploitation: trafficked pe

160 se due to increased observation and sampling effort, or to an actual rise in the abundance of parasit

161 ess and has been an area of intense research effort over the past two decades.

162 Despite intense research and clinical efforts, patients affected by advanced colorectal cancer

163 Inspiratory effort reduction by NIV was linearly related to inspirat

164 ocess), and then review extant translational efforts regarding these targets and the evidence support

165 Effort-related decision-making and reward learning are b

166 profiling approaches have accelerated these efforts, revealing ILC2 transcriptional programs that ar

167 The analysis of our extensive computational efforts reveals that social distancing and quarantining

168 t effort (CPUE) and species density per unit effort (SDPUE) data for non-clupeid fish and soniferous

169 bal emissions budget calculation method, and effort-sharing approach, taking New Zealand (NZ) as a ca

170 r shellfish production, and these mitigation efforts should be incorporated into breeding programs fo

171 Efforts should be made to improve adherence to screening

172 Future research efforts should elucidate the functional consequences of

173 In the context of global malaria elimination efforts, special attention is being paid to submicroscop

174 trade-off between male mating and parenting effort suggests different possibilities for using paleo-

175 ided an up-to-date account of drug discovery efforts targeting selected enzymes (MbtI, MbtA, MbtM, an

176 tly less mental demand, physical demand, and effort, than open or laparoscopic (P < 0.05).

177 onvened a joint VA/DoD guideline development effort that included clinical stakeholders and conformed

178 ed in forensic laboratories and the time and effort that must be invested for intralaboratory method

179 f their choice, unlike existing acceleration efforts that sacrifice some aligner capabilities.

180 is in the realm of nuclear nonproliferation efforts, the ubiquitous use of cloth swipes across many

181 d severe challenges on laboratories in their effort to achieve sufficient diagnostic testing capabili

182 t) that highlights an interprofessional team effort to address and mitigate the effects of SDOH in an

183 In an effort to ameliorate this devastation, the biomedical re

184 exert similar effort to gain reward but less effort to avoid punishment when compared with healthy ag

185 as prompted an unprecedented global research effort to better understand this virus and to identify p

186 was measured in November 2019 as part of an effort to catalogue all large (>= 2 m diameter) Porites

187 In an effort to circumvent these issues, different strategies

188 Here, we present an effort to create a "clean" Chinese hamster ovary (CHO) c

189 essive cortical and cerebellar atrophy in an effort to determine the genetic aetiology underlying neu

190 We suggest that the effort to determine the neural basis of adaptive behavio

191 In our effort to develop FR-targeted SMDCs with varying mechani

192 d Parkinson's disease patients exert similar effort to gain reward but less effort to avoid punishmen

193 e of SARS-CoV-2 has driven a global research effort to identify medical countermeasures at an unprece

194 In an effort to identify these components, we screened the gen

195 In an effort to improve this situation, we have developed a co

196 We report a major effort to increase the coverage of structural data, aimi

197 tatistical Computing, Vienna, Austria) in an effort to lower implementation barriers to ultimately im

198 Here, in an effort to make better use of the experimental techniques

199 ow that healthy human individuals exert more effort to minimize punishment than to maximize reward (l

200 on on functional readouts of chromatin in an effort to prioritize variants in terms of their impact o

201 In the effort to provide food in terms of calories, the essenti

202 alysis underlines the need for a coordinated effort to quantify the genetic and biochemical diversity

203 Effort to raise public awareness screening for lung canc

204 In an effort to reduce the charge of membrane proteins, we exa

205 irst, charges are assigned to CG beads in an effort to reproduce molecular multipole moments and char

206 In an effort to search for the host cellular protein(s) mediat

207 hundreds of clinical trials in an expedited effort to understand, prevent, and treat this disease.

208 l benefit from a more explicit and concerted effort to work together.

209 for many infections, is an important part of efforts to address antimicrobial resistance.

210 Our findings encourage larger efforts to apply chemoproteomic methods to assist in tar

211 of M. haemolytica pathogenesis has hampered efforts to better understand the molecular interactions

212 es hold considerable promise to push forward efforts to combat Alzheimer's disease and other neurodeg

213 Efforts to convert the diosphenol (-)-myrocin G (4) to t

214 In this Perspective, we describe efforts to decipher heterogeneity in T2D and detail how

215 regulation of immune cell signaling, current efforts to define its roles in disease processes, and ap

216 Additionally, efforts to detect these predicted RNA products in sample

217 be rigorously evaluated in ongoing curation efforts to determine their validity as Mendelian DCM gen

218 Efforts to develop antiviral strategies for treating MS

219 siderations and there have been considerable efforts to develop more selective processes for less con

220 Recent efforts to develop neural signals of language comprehens

221 EE against cocaine seeking, which may inform efforts to develop pharmacological and gene therapies fo

222 pathophysiology and may catalyze cooperative efforts to develop tinnitus therapies.

223 Prior efforts to discover a useful sortase inhibitor have reli

224 stigation of these groups will guide ongoing efforts to discover potential risk factor and assist wit

225 the first test in antenatal care to support efforts to eliminate MTCT of HIV and syphilis.

226 Finally, despite our best efforts to enhance measurements and IOL calculations, re

227 Hence, future efforts to enhance the efficiency of electrocatalytic MO

228 ed fishing in concentrated areas and ongoing efforts to establish a Marine Protected Area along the P

229 Prior efforts to fabricate dissolving undercut microstructures

230 ble based on allometric scaling, but similar efforts to find universal predictive relationships for a

231 Previous efforts to form two-dimensional dilute magnetic semicond

232 conformation, represent unique platforms for efforts to harness principles of enzyme function for cat

233 t in type 1 and 2 diabetes, which has led to efforts to identify molecules to promote beta-cell proli

234 Herein, we disclose our efforts to identify potent, selective, and orally bioava

235 eview the findings and limitations of recent efforts to identify relatively "autism-specific" genes,

236 tions to molecular mechanisms and highlights efforts to identify the causal variant and effector tran

237 , and this lack of clarity is detrimental to efforts to identify therapeutic targets.

238 as of future investigations to guide further efforts to implement ultrasensitive resistance testing i

239 Consequently, efforts to improve antibiotic stewardship should be coup

240 different populations or contexts, hindering efforts to improve bee health.

241 ison of outcomes among studies, and enhances efforts to improve the measurement of these core clinica

242 Efforts to improve upon the prime-boost vaccine regimen

243 Efforts to include precision measures of metabolic healt

244 Despite efforts to increase arteriovenous fistula and graft use,

245 proaches: maximizing the HIV care workforce (efforts to increase the number of existing healthcare wo

246 nticipate that this approach will facilitate efforts to investigate mechanisms driving tumor progress

247 proteins, and will guide protein engineering efforts to leverage this system for programmable DNA ins

248 Past efforts to make spatially resolved proteome measurements

249 holistic view is required as part of future efforts to manage the krill fishery that incorporates va

250 Our findings suggest that stewardship efforts to minimize and improve fluoroquinolone prescrib

251 ected MTDLs and highlight some of the recent efforts to obtain these new classes of MTDLs as potentia

252 macokinetics (PK) at infection sites hinders efforts to optimize antimicrobial dosing and shorten TB

253 While efforts to perform targeted drug delivery by engineered

254 versity suggest contrasting implications for efforts to predict how consumers will respond to climate

255 Most efforts to predict novel reservoirs of zoonotic pathogen

256 In light of these results, efforts to prevent cardiometabolic complications in PCOS

257 ention measures, and increasing surveillance efforts to prevent further expansion of ZIKV.

258 Efforts to quantify behavior at scale are impeded by the

259 However, to date, efforts to rapidly and comprehensively identify bacteria

260 These findings will help focus future efforts to recognize and prevent DDD.

261 y demersal otter trawls, warrant intensified efforts to reduce discards.

262 ur findings are confirmed, they could inform efforts to reduce elective CS rates that are not clinica

263 While countries are increasingly making efforts to reduce poverty and hunger by pursuing sustain

264 hat better characterize diversity and assess efforts to reduce the barriers that exist for potential

265 entiation that warrants future translational efforts to repurpose phenformin for the treatment of cut

266 Efforts to resolve quantum states with spectroscopic too

267 While efforts to restore and protect mangroves appear to be ef

268 Efforts to sequence single protein molecules in nanopore

269 There have been efforts to sequence the genomes of additional ancient pa

270 Recent efforts to target autophagy in cancer have focused on ki

271 treating certain hematological malignancies, efforts to translate this success to solid tumors have m

272 oncoding regions; this knowledge gap impairs efforts to understand the molecular mechanisms of AF and

273 ished in biological environments, precluding efforts to visualize multicellular processes.

274 t that is poorly tissue penetrant, hindering efforts to visualize targets in deep tissues.

275 ation is of particular importance for future efforts toward establishing prophylactic interventions f

276 of carbon dots (CDs) have motivated research efforts toward their incorporation into commercial produ

277 trategy for patients with basal-like BC, and efforts toward this end are currently underway.

278 type; this article describes several current efforts toward this goal.

279 critical in modern science, and requires an effort towards standardising data publication practices.

280 considered as an important prerequisite for efforts towards miniaturization.

281 major opportunity as we direct our research efforts towards one of the most pressing problems facing

282 These findings will help efforts towards the discovery of microbial-derived repel

283 Efforts typically focus on specific packaging characteri

284 t to detect predefined potentially injurious effort was tested using derivation and validation datase

285 To aid in this effort, we developed a general population risk calculato

286 In a worldwide collaborative effort, we evaluated 231 individuals harboring 105 disti

287 In a comprehensive in situ hybridization effort, we show that the zebra finch vocal robust nucleu

288 Despite extensive efforts, we were unable to reproduce the finding that gl

289 These initial efforts were centered around blood protein adsorption on

290 oronic acid program that led to vaborbactam, efforts were directed toward expanding the spectrum to a

291 rovides heterogeneous mixtures, while heroic efforts were required to complete chemical and/or enzyma

292 Practitioner independence should focus their efforts when attempting to remove restrictions on Nurse

293 identify relatively "autism-specific" genes, efforts which focus on rare variants of large effect siz

294 al tree and highlight areas where additional effort will be required.

295 Continued vigilance and anti-poaching efforts will be necessary to combat poaching and to cons

296 Future efforts will evaluate interventions to improve colonosco

297 polymers by those interested in joining the effort with this fascinating and emerging class of 2D ma

298 This study sought to report these efforts with a detailed methodology for which institutio

299 ted with exclusive focus of ligand discovery efforts within only one framework.

300 Our efforts yielded low-molecular weight compounds that bind