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1 oteins that form the insoluble matrix of the egg coat.
2 ependent mechanism for sperm adhesion to the egg coat.
3 teins ZP2 and ZP3, are part of the mammalian egg coat.
4 lity and, therefore, failed to penetrate the egg coat.
5 the evolution of components of the mammalian egg coat.
6 (zona pellucida) to allow penetration of the egg coat.
7 cida 3 (ZP3), a protein present on the avian egg coat.
8 essential for sperm penetration through the egg coats.
9 omain are prominent components of vertebrate egg coats.
10 and that is peripherally associated with the egg coat and facilitates gamete adhesion; and a ZP3-depe
12 r interactions, such as sperm binding to the egg coat and macrophage recognition of apoptotic lymphoc
13 ly cross-links ZP filaments, rigidifying the egg coat and making it physically impenetrable to sperm.
14 em, coevolution between adaptively diverging egg coat and sperm proteins may contribute to the rapid
15 ly, from serving as structural components of egg coats, appendicularian mucous houses, and nematode d
16 inence of ZP proteins as constituents of the egg coat, as well as the prominent role of positive sele
17 reover, the structure of a native vertebrate egg coat filament, combined with AlphaFold predictions o
22 rtilization of an egg by a single sperm, the egg coat or zona pellucida (ZP) hardens and polyspermy i
24 Many features of mammalian and non-mammalian egg coat polypeptides have been conserved during several
25 now reveal the crystal structures of mollusk egg coat protein, VERL, complexed with cognate sperm pro
28 , identifying the pattern of evolution among egg coat proteins is important in understanding the role
33 nity to test this hypothesis since the avian egg coat tolerates physiological polyspermy, or the pene
34 characterize the constituent proteins of the egg coat [vitelline envelope (VE)] of abalone eggs and t