ライフサイエンスコーパス: elaboration

1 nctionality as a handle for further chemical elaboration.

2 tic volume changes and astrocytic structural elaboration.

3 regions function similarly during search and elaboration.

4 acting on neurons to enhance dendritic arbor elaboration.

5 ators, but their importance warrants further elaboration.

6 ation of content generation deserves further elaboration.

7 s was associated with iNOS expression and NO elaboration.

8 cting on neurons to increase dendritic arbor elaboration.

9 genous miR-34a expression enhances dendritic elaboration.

10 erves as a diversification point for further elaboration.

11 oam cell formation and inflammatory cytokine elaboration.

12 d its metabolic baggage at the moment of its elaboration.

13 ogenesis and oligodendrocyte progenitor cell elaboration.

14 nteroception), and the results of perceptual elaboration.

15 groups at C2), providing handles for further elaboration.

16 compounds, are amenable to useful synthetic elaboration.

17 the motor's stator system and its structural elaboration.

18 development, from axon repulsion to dendrite elaboration.

19 he levels of oig-8 results in an increase in elaborations.

20 , whereas temporal fate diversifies terminal elaborations.

21 ay neuron-type-specific patterns of membrane elaborations [1-3], but it is not well understood how su

22 ental genetics of corolla tube formation and elaboration 697 VI.

23 Stipules and ligules: ontogeny of primordial elaborations 715 VII.

24 Through computational modeling and synthetic elaboration, a potent GLO1 inhibitor was developed with

25 aken at three different times throughout the elaboration: after fermentation, after post-fermentation

26 Statistical data elaboration allowed determining the main processes occur

27 activation of macrophages enhanced cytokine elaboration alone, as well as in combination with LPS or

28 Blocking O-glycan elaboration also partially blocked viral entry.

29 tion of negative emotions requires cognitive elaboration and closure, whereas hedonistic reward is co

30 g the olfactory receptors contributed to the elaboration and development of the electronic smell syst

31 xylic acids that allow for greater molecular elaboration and enhanced hydrogen bonding capabilities.

32 ve JNK isoform that results in growth factor elaboration and ERK1/2 cell cycle activation.

33 graded indicators linger, resulting in trait elaboration and exaggeration.

34 nols provides numerous avenues for synthetic elaboration and exciting opportunities for bioisosteric

35 adical polycyclization cascade for divergent elaboration and functionalization.

36 monitoring of marine environments and in the elaboration and management of future conservation plans.

37 zatin has a selective role in the structural elaboration and postnatal maturation of murine neuromusc

38 LH) innate immune response to control Chi3l1 elaboration and pulmonary metastasis.

39 nd hue, with the latter allowing faster data elaboration and real-time display of the results.

40 nderstanding energetic costs of evolutionary elaboration and reduction of the mouthparts and insect d

41 ritical for early activity-dependent circuit elaboration and refinement in the mammalian visual syste

42 lin amassed in the periplasm for rapid pilin elaboration and subsequent BRP production to promote col

43 nal signaling is needed to support the arbor elaboration and synaptic connectivity of dLGN interneuro

44 This work has first consisted in the elaboration and the characterization of a robust and rep

45 or of tumor progression and metastasis whose elaboration and tissue effects are abrogated by RLH inna

46 The present study aimed at the elaboration and validation of a method to determine PAs

47 new synthetic strategies for heteroaromatic elaboration, and are useful in their own right in pharma

48 nextricably interwoven, allowing distortion, elaboration, and even total fabrication.

49 ental genetics of corolla tube formation and elaboration, and the molecular basis of floral trait div

50 that our target article and the criticisms, elaborations, and extensions of the commentators can be

51 Two data elaboration approaches for evaluating olive oils authent

52 de the first experimental evidence for vocal elaboration as a male-specific strategy to maintain soci

53 via this route provide a useful platform for elaboration, as demonstrated by the preparation of a var

54 yloxazole is a useful scaffold for synthetic elaboration at the 2-methylene position thereby affordin

55 d by multiple BC4s through ongoing dendritic elaboration between 1 and 6 months of age-well into matu

56 or Sema3A-mediated cortical neuron dendritic elaboration but is dispensable for inhibitory axon guida

57 that Rac1 activity is required for dendrite elaboration but not axon growth cone collapse.

58 te Sema3A-mediated cortical neuron dendritic elaboration, but not inhibitory axon guidance.

59 Indeed, IFN-gamma elaboration by HIF-deficient in vivo-generated Tfh cells

60 Stimulating either eye alone reduced axon elaboration by increasing branch loss.

61 e as a superior template (vs purine) and its elaboration by introduction of C4-benzenesulfonamide and

62 Metabolite tracking and chemical elaboration combined with 3D-quantitative structure-acti

63 naling in vitro and in vivo alters dendritic elaboration: Dendrites are longer and more complex when

64 This explanation and elaboration document describes the intent and rationale

65 This explanation and elaboration document describes the rationale for includi

66 This explanation and elaboration document describes the rationale; clarifies

67 This explanation and elaboration document was developed as part of the revisi

68 A more detailed explanation and elaboration document, describing the interpretation and

69 Statement, together with its explanation and elaboration document, may guide future analyses and repo

70 o developed the accompanying Explanation and Elaboration document, which serves (1) to explain the ra

71 ems and is accompanied by an explanation and elaboration document.

72 conjunction with the TRIPOD explanation and elaboration document.

73 o developed the accompanying Explanation and Elaboration (E&E) document, which serves (1) to explain

74 nd includes latent functionality for further elaboration (e.g., aliphatic alcohols, alpha,beta-unsatu

75 is, which include dendritic arbor growth and elaboration followed by retraction and pruning.

76 rs of Maillard reaction (MR) in black garlic elaboration, followed by the determination of furosine b

77 ranscription factors, whereas other marginal elaboration genes are dispensable for its maintenance.

78 y of the thiol-alkynylation in postsynthetic elaboration has been demonstrated through the facile ins

79 put screening with structure-guided compound elaboration has yielded a tool compound that may serve a

80 nificantly above chance, but the more recent elaborations have achieved relatively little performance

81 rophil infiltration and host defense peptide elaboration in lesions.

82 ators to monitor the process of black garlic elaboration in order to obtain high quality products.

83 is a major regulator of dendrite growth and elaboration in the developing brain.

84 re in accord with the THP ring formation and elaboration in thiomarinol following a similar order to

85 regulator of flotation and virulence factor elaboration in this strain.

86 s a key regulator of astrocyte morphological elaboration in vivo.

87 oth active site specialization and new motif elaborations in protein and RNA subunits.

88 t contains the checklist and explanatory and elaboration information to enhance the use of the checkl

89 tion throughout the Permian, with functional elaboration initially being more strongly expressed in t

90 Further elaboration into a polycyclic ring system via alcohol ox

91 amides with the possibility of their further elaboration into a variety of biologically important het

92 icateins are promising candidates for future elaboration into efficient and selective biocatalysts fo

93 id foundation for successful structure-based elaboration into potent inhibitors.

94 d isocyanides are ideally functionalized for elaboration into synthetic targets as illustrated by the

95 ng blocks that can undergo further synthetic elaboration is highlighted in the preparation of trifluo

96 Weinreb carboxamide, further chemoselective elaboration leads to the efficient formation of librarie

97 llographic structures were used to guide the elaboration/linking of the fragment, ultimately leading

98 motor cortex to brainstem nuclei, to complex elaborations, mediated by high-order cognition and foste

99 Further synthetic elaboration of 8TQ yielded a small molecule compound (35

100 ropose a friendly protocol that includes the elaboration of a homogeneous deposit by spray coating fo

101 in neural progenitors to promote subsequent elaboration of a mature neuronal phenotype.

102 Thus, the elaboration of a protocol for the in vitro cultivation o

103 s (DMPK) properties was initiated based upon elaboration of a simple pyridone core.

104 the mechanism of this reaction, enabling the elaboration of a stereochemical model that can rationali

105 ell lineages to occur concomitantly with the elaboration of a three-dimensional body plan during gast

106 bnormalities are likely a consequence of the elaboration of a variety of inflammatory cytokines gener

107 binding to short DNA molecules, allowing the elaboration of a variety of intercalator displacement as

108 d will simplify the synthesis and structural elaboration of amine-containing targets.

109 , particular attention has been given to the elaboration of an "aberrant spectra" detection strategy

110 ma, reaching a higher level of awareness and elaboration of an active prevention plan is mandatory.

111 aarenes but also proves to be useful for the elaboration of an array of biorelevant tetrahydro-[1,6]-

112 largely the same developmental program or by elaboration of an existing root program in the common an

113 that multiple S100 proteins can repress the elaboration of an oncogenic bacterial surface organelle.

114 We propose an elaboration of Anselme and Gunturkun's research that con

115 tork et al. (2014) report that extension and elaboration of astrocyte processes in Drosophila is cont

116 We propose that lineage-specific elaboration of axoneme structure in T. brucei reflects a

117 roughout development - from migration to the elaboration of axons and dendrites - that are correctly

118 role for protein quality control during the elaboration of bacterial biofilm in the context of an in

119 Elaboration of Bayesian phylogenetic inference methods h

120 riod plasticity is strongly dependent on the elaboration of brain-derived neurotrophic factor (BDNF),

121 in histological injury, and markedly reduced elaboration of cardiac troponin-I in coronary effluent d

122 the plant functions that are involved in the elaboration of cell wall damage-induced immune responses

123 l hit-to-lead optimization assumes that upon elaboration of chemical structure, the ligand retains it

124 table dipole precursors was explored for the elaboration of chiral cyclohexanones.

125 instructs the distinct, neuron-type-specific elaboration of ciliated endings of different olfactory n

126 ll which appears to promote inflammation via elaboration of complement-dependent anaphylatoxins.

127 le and antioxidant capacity change along the elaboration of cooked pasta, being the cooking step impo

128 les for Eph signaling, first in limiting the elaboration of cortical neuronal dendrites and then in c

129 n evolution; (ii) subsequent vocal-laryngeal elaboration of cortico-basal ganglia circuitries, driven

130 alysis was followed by extensive statistical elaboration of data, literature data mining, and gene on

131 iking and opposite effects on the growth and elaboration of dendrites among major classes of brain ne

132 hite matter, in addition to neuronal growth, elaboration of dendrites, and amplification of neuropil

133 dence for their inclusion in the guidelines, elaboration of details to report, and examples of good r

134 plant form is achieved through differential elaboration of developmental pre-patterns during postemb

135 The left-sided parapineal promotes the elaboration of dHbl character in the left habenula, albe

136 ervating motor neuron subtypes parallels the elaboration of digits.

137 While the size, shape, number and elaboration of each of these organ types can be quite di

138 can provide a new, much needed, tool for the elaboration of effective public health intervention plan

139 The elaboration of excitatory projection neuron (PN) process

140 New functions commonly evolve by elaboration of existing scaffolds, for example, via doma

141 that probiotics alter gut flora and lead to elaboration of flora metabolites that influence health t

142 4b, opening interesting perspectives on the elaboration of fluorescent cavity-based systems for the

143 urs that could be used as ingredients in the elaboration of foods with a good nutritional profile.

144 the use of amaranth protein/peptides in the elaboration of functional foods for hypertensive individ

145 imal model initially developed to facilitate elaboration of genetic influences on behavior.

146 carbon nanotubes (vaCNT) have been used for elaboration of glucose/O2 enzymatic fuel cells exploitin

147 of others that resulted in an age-dependent elaboration of hedonic-response-specific circuitry despi

148 ening, followed by structure-guided chemical elaboration of hits, led to the rapid development of dru

149 of modern medicine and allostasis, a further elaboration of homeostasis, has been defined as stabilit

150 provement of technological processes for the elaboration of hypocaloric and functional beverages.

151 IRI promotes elaboration of IL-18 from endothelial cells to selective

152 to activation of the NLRP3 inflammasome and elaboration of IL-18.

153 multiple lipid-binding proteins lead to the elaboration of increasing layers of the SSR and uncover

154 ntations in humans, presumably involving the elaboration of inhibitory circuits, is dependent on expe

155 p8 is an important factor for initiation and elaboration of inner ear development.

156 EPCR deficiency attenuated the elaboration of interleukin-6, infiltration of macrophage

157 assive expansion of the cortical surface and elaboration of its connections in humans originates from

158 Alternatively, elaboration of l-serine gave the corresponding enantiopu

159 ght into these principles by considering the elaboration of locomotor circuits across evolution.

160 ics and can be used as an alternative in the elaboration of low glycaemic index foods.

161 Elaboration of lymphangiogenic growth factors and matrix

162 d form of consciousness is necessary for the elaboration of meaningful associations.

163 e suppression of storage proteins led to the elaboration of membrane stacks enriched with oleosin (si

164 ge is a widely applied, robust technique for elaboration of metal-organic frameworks (MOFs) post-synt

165 ique in ynamide chemistry and allows for the elaboration of metalated enamides that are useful buildi

166 from C1 and fixation of MHC-C drove further elaboration of MHC-C-specific KIR, as exemplified by chi

167 n layers of other cortical areas and for the elaboration of models of circuit function that incorpora

168 fibrotic activation state, along with serial elaboration of monocyte and eosinophil recruitment facto

169 of vocal displays afforded by the preceding elaboration of monosynaptic corticobulbar tracts, giving

170 The elaboration of nascent synaptic connections into highly

171 een found in a high concentration during the elaboration of natural green olives.

172 an ancestral SoxE gene may have facilitated elaboration of NC lineages.

173 utations in vertebrate homologues, promoting elaboration of NC traits.

174 al cortical function depends upon the proper elaboration of neurons, including the initial extension

175 nolic content they could be suitable for the elaboration of new ingredients with different industrial

176 Answering these questions should allow the elaboration of new interpretative methods based on objec

177 le liposomes and polymersomes called for the elaboration of new synthetic methodologies.

178 al curiosities to important reagents for the elaboration of organic molecules.

179 that cannot die by apoptosis because of the elaboration of pathogen-encoded caspase inhibitors.

180 ion of new cell types, and the emergence and elaboration of patterning mechanisms to organise cells i

181 ii genome but co-culture is required for the elaboration of PDGA depolymerase activity.

182 vascular tissues for normal organization and elaboration of plant vascular tissue.

183 cell numbers and neuronal cell types to the elaboration of progenitor populations and their prolifer

184 l alteration of rRNA structure to enable the elaboration of proteins and peptides containing noncanon

185 ut not global knockout of GluD2 causes under-elaboration of Purkinje cell dendrites in the deep molec

186 T cells regulate blood pressure through the elaboration of reactive oxygen species and vasoactive cy

187 medium containing oxazole 2 resulted in the elaboration of RRM1 containing the oxazole.

188 ial importance in modern engineering for the elaboration of safety regulations in structural design o

189 each isoform has a distinct function in the elaboration of sexually dimorphic circuitry and behavior

190 ersatile intermediates that enable the rapid elaboration of simple alkene precursors.

191 n reactions that generate complexity through elaboration of simple starting materials.

192 tion is particularly challenging because the elaboration of specific shapes is in essence a question

193 resumed underuse of epilepsy surgery and the elaboration of strategies to address this treatment gap

194 Ackermann et al. outline a model for elaboration of subcortical motor outputs as a driving fo

195 Finally, we describe the elaboration of such modified proteins both in vitro and

196 ve TH2 inflammation or to suppress the local elaboration of TH2-promoting epithelial factors, such as

197 sociality, and we begin our response with an elaboration of that definition and a defense of our argu

198 This paper proposes an elaboration of the AoP Natural Resources.

199 bryos refocus from increasing cell number to elaboration of the body plan.

200 identify three "working edges" for fruitful elaboration of the Chunk-and-Pass proposal: (a) accounti

201 hydration is the key step in the subsequent elaboration of the cis-2,8-dioxabicyclo[3.3.0]octan-3-on

202 Our results thus require an elaboration of the currently prevailing model for ON mot

203 ting of Centrosomin to Golgi outposts during elaboration of the dendrite arbor creates a local system

204 d by a Stille cross-coupling is used for the elaboration of the desired substituted dienes which will

205 ication, polycyclic systems have arisen from elaboration of the diene motif.

206 erges over the first few years of life as an elaboration of the earlier, and more open-ended, intuiti

207 ge storage and information processing or the elaboration of the electrochemically switchable devices.

208 SADs, together with AAD1, participate in the elaboration of the embryonic cuticle, a barrier essentia

209 Further elaboration of the genetics of DLBCL will not only impro

210 algranulin A/B) binds zinc and represses the elaboration of the H. pylori cag type IV secretion syste

211 attributed to the evolutionary expansion and elaboration of the human cerebral cortex.

212 phila melanogaster embryos, we show that the elaboration of the interphase Cnn scaffold defines a maj

213 enes encode the activities that initiate the elaboration of the Manalpha1-3 and Manalpha1-6 arms, res

214 rs, the ensheathment of axons and subsequent elaboration of the myelin sheath.

215 Elaboration of the N-O moiety of one member of this libr

216 However, elaboration of the neurochemical pathways that govern ag

217 ial-specific regulatory circuit, allowed the elaboration of the new head during vertebrate evolution.

218 on of a highly interactive interface and the elaboration of the notion of this map of medicine acting

219 entifies a downstream component required for elaboration of the pre-pattern.

220 Structural elaboration of the products to obtain dihydrobenzoquinaz

221 coding a small regulatory RNA), show reduced elaboration of the quorum sensing molecule (N-3-oxohexan

222 ral whorls and is best interpreted as a late elaboration of the region between the petals and stamens

223 The elaboration of the resorcin[4]arene's aromatic cavity pr

224 "pyridylic" C-O bond in this tetracycle and elaboration of the resultant hydroxy ketone to a diketon

225 matically derived cis-1,2-dihydrocatechol 3, elaboration of the resulting adduct to the tricyclic ket

226 Elaboration of the resulting substituted N-hydroxy-2-aze

227 The elaboration of the results was supported by chemometric

228 HADSF subfamily having the least structural elaboration of the Rossmann fold catalytic domain was th

229 cells termed meristems, which allow for the elaboration of the shoot, root, and vascular systems.

230 Consistent with its function in the elaboration of the sieve areas, CHER1 has a sustained, p

231 al of the directing SO2Py allows for further elaboration of the silylation products.

232 7 pairs (14%), the binding mode changes upon elaboration of the smaller ligand.

233 n brain evolution has been attributed to the elaboration of the subventricular zone (SVZ) and the ass

234 Further in situ elaboration of the sulfinate intermediates leads to the

235 thiolactone ring is a suitable position for elaboration of the TLM scaffold, and the structure-activ

236 of disease and patient participation in the elaboration of the treatment plan is expected to substan

237 e basis of these observations, we propose an elaboration of the two-site, two-step model-the "three-s

238 Two strategies have been examined for elaboration of the unsaturated tetrahydrofuranyl ring fr

239 ng the mechanisms that control induction and elaboration of the vertebrate central nervous system (CN

240 to a range of derivatives through subsequent elaboration of the xanthate group.

241 studied, the process leading to the precise elaboration of their comb-like shapes remains elusive.

242 Elaboration of these beta,gamma-diamino and alpha-hydrox

243 The origins and subsequent elaboration of these compartments represent a key aspect

244 Elaboration of these compounds to target binding hotspot

245 al or financial support was received for the elaboration of these recommendations.

246 The elaboration of these structures toward the asymmetric sy

247 Several examples demonstrate further elaboration of this functionality.

248 A logical elaboration of this idea leads to a dynamical neural arc

249 Elaboration of this simple functionalization allows prep

250 Elaboration of this topic can lead to a better understan

251 parity and breast cancer risk may allow the elaboration of tools to predict and survey those who are

252 ucleotides is a critical initial step in the elaboration of type I IFN.

253 n of vimentin filaments in repair cells, the elaboration of vimentin-rich protrusions, and wound clos

254 halon could be simplified by viewing them as elaborations of a much more finite group of developmenta

255 desymmetrization of naphthalene, as well as elaborations of amine-containing drug molecules.

256 The various elaborations of corolla tube attributes, such as length,

257 However, the morphological elaborations of several amphid cilia are different betwe

258 provides a solid foundation for the further elaborations of several natural products.

259 also uncovered previously unknown structural elaborations of the alphaproteobacterial flagellar motor

260 d vestibular systems, harbor two specialized elaborations of the apical surface, the hair bundle and

261 r synthesis in land plants, and suggest that elaborations of the linear polymer, such as branching or

262 stic understanding of the formation of these elaborations of the lining of the gut, essential for pro

263 Structural elaborations of these highly substituted isoxazoles by S

264 Future elaborations of this concept to extend its capabilities

265 leaves are distinguished by the differential elaborations of upper and lower leaf zones, the formatio

266 These elaborations often differ dramatically among closely rel

267 rest evolution postulate vertebrate-specific elaborations on an ancestral neural plate border program

268 gage the same neural regions during a detail elaboration phase that younger adults engage during memo

269 However, during the later elaboration phase, the same posterior regions were assoc

270 memory search phase and a subsequent detail elaboration phase.

271 Acrylamide was not detected during the elaboration process and after HHP treatment.

272 r studies the impact of the strawberry puree elaboration process on the chemical composition of the f

273 d glucose significantly increased during the elaboration process, contributing to the sweetness of bl

274 ase-HPLC methods along different procedures: elaboration process, high hydrostatic pressure (HHP), co

275 the formation of these bioactives during the elaboration process.

276 the different steps of production, for three elaboration processes and two harvests (2011 and 2012).

277 earomatized products are amenable to further elaborations, providing functionalized alicyclic motifs

278 We also need to improve model elaboration, refinement and coarse graining procedures t

279 vides examples of good reporting, as well as elaborations regarding the rationale for new checklist i

280 a similar developmental synaptic pruning and elaboration strategy is used at both sites to generate t

281 r results suggest an evolution of structural elaboration that may have enabled pathogenic bacteria to

282 d products are amenable to further synthetic elaboration through manipulation of the olefinic functio

283 yclization yields a novel cyclopentenone for elaboration to 1.

284 unctionalized aza-octahydropentalene and its elaboration to a model tetracyclic core structure of cal

285 ODIPY offer a glimpse into the potential for elaboration to a panoply of chromophores with diverse ph

286 Under either scenario we expect sexual trait elaboration to be countered by proximate constraints roo

287 ic synthesis of tylactone and its subsequent elaboration to complete the first total synthesis of the

288 he active site, followed by structure-guided elaboration to design potent nanomolar inhibitors agains

289 ed C-H arylation reactions, allowing for the elaboration to diversely functionalized building blocks.

290 selective way and used for further synthetic elaboration to produce, for example, a CF3-substituted 2

291 aturated esters gave a range of diamines for elaboration to T1-T8 via a sequence involving reduction

292 , has been accomplished along with synthetic elaboration to their C14-epimers starting from d-glucose

293 Core elaboration ultimately yielded a compound that showed ac

294 d diketopiperazine formation upon subsequent elaboration using 9-fluorenylmethoxycarbonyl solid-phase

295 phosphine products as substrates for further elaboration was demonstrated with a platinum-catalyzed a

296 nventional chemical analysis and chemometric elaboration were used to assess quality and to define an

297 es by a combination of selective pruning and elaboration, whereas laminar restriction results from bi

298 les, could be further utilized for synthetic elaboration, which is advantageous for biological evalua

299 enamines could be further used for synthetic elaboration, which proved to be highly advantageous for

300 rough a click reaction, which allows further elaboration with streptavidin-conjugated dyes or other m