ライフサイエンスコーパス: elderly

1 subgroups with poor uptake (e.g., women and elderly).

2 key risk factor for chronic diseases of the elderly.

3 able on immune responses to norovirus in the elderly.

4 perties of L-dopa supplements in the healthy elderly.

5 panded to new patient cohorts, including the elderly.

6 ssociated with depressive symptoms among the elderly.

7 urden among adults overall and those who are elderly.

8 e and impact of pneumococcal vaccines in the elderly.

9 and has become increasingly prevalent in the elderly.

10 s 26%) (p = 0.011) were more frequent in the elderly.

11 have been shown to be less responsive in the elderly.

12 amino acid utilization may be reduced in the elderly.

13 rder and a leading cause of blindness in the elderly.

14 ealth and reverse periodontal disease in the elderly.

15 portant cause of death and disability in the elderly.

16 ading cause of irreversible blindness in the elderly.

17 largest increase in number of deaths in the elderly.

18 nding of hCoV-induced fatal pneumonia in the elderly.

19 related to higher incidence rates among the elderly.

20 the efficacy and safety of therapies in the elderly.

21 cline in selective attention observed in the elderly.

22 s 1% of men, with increased incidence in the elderly.

23 wever, the incidence rate has doubled in the elderly.

24 observed propensity of clinical cases in the elderly.

25 (VE) in recent years, particularly among the elderly.

26 , particularly in children 5-9 years and the elderly.

27 prevalent degenerative joint diseases in the elderly.

28 oVs) cause severe respiratory illness in the elderly.

29 ning host defenses in the lung mucosa of the elderly.

30 s associated with increased mortality in the elderly.

31 1 gene delivery was well tolerated among the elderly.

32 cline remains an unaddressed problem for the elderly.

33 e pain throughout adulthood than did today's elderly.

34 health as well as the social impacts on the elderly.

35 act disease and mortality in infants and the elderly.

36 ncy with poor prognosis, particularly in the elderly.

37 can cause severe disease in children and the elderly.

38 ults, and weight loss was more common in the elderly.

39 ion (AMD), a major cause of blindness in the elderly.

40 Complications were more frequent in the elderly.

41 e Pharmaceutical Assistance Contract for the Elderly (1999-2002) and Medicaid Analytic eXtract (2000-

42 Surgery was more frequently performed in the elderly (20% vs 9%, p = 0.02), while biological therapy

43 Of 897 (80%) VP, there were 465 (41%) elderly, 380 (34%) racial/ethnic minorities, and 479 (43

44 Of the 949 men, 212 (22%) were elderly, 493 (52%) Caucasian, 254 (27%) current smokers,

45 midbrain tissues of young (25-38 years) and elderly (61-85 years) adults.

46 4-fold increase in mortality compared to non-elderlies (adjusted hazard ratio[aHR] 4.79, p<0.001).

47 ics in elderly (aged 65-85 years) versus non-elderly adults (aged 18-64 years).

48 developing heart failure in community-based elderly adults during up to 14 years of follow-up.

49 We studied 1099 community-based elderly adults participating in the Rush Memory and Agin

50 e severe respiratory diseases in infants and elderly adults(1).

51 nd has been tested clinically in toddlers to elderly adults.

52 about the eczema phenotype in middle-aged or elderly adults.

53 f loss of muscle mass and quality of life in elderly adults.

54 r incidence of depressive symptoms among the elderly after adjusting all confounders (OR=0.83, 95% CI

55 common inflammatory rheumatic disease of the elderly after rheumatoid arthritis.

56 10(-8)) with ALM in a population of 181,862 elderly (aged 60-74 years) individuals from UKB.

57 was to compare pimodivir pharmacokinetics in elderly (aged 65-85 years) versus non-elderly adults (ag

58 ro-oxidative and proinflammatory pathways in elderly ALF and decreased binding capability of surfacta

59 osome fusion events, which was reversed when elderly ALF was replenished with functional SP-A/SP-D.

60 Human macrophages infected with elderly ALF-exposed Mtb had reduced control and fewer ph

61 is has similar presentation and behaviour in elderly and adults patients.

62 is research on managing long-term care among elderly and disabled Medicaid recipients.

63 er bypass are preserved across both Medicare elderly and disabled subpopulations.

64 Pimodivir pharmacokinetic parameters in non-elderly and elderly patients were similar.

65 e latest published research on assessment of elderly and frail lung transplant candidates.

66 es of respiratory infections in children and elderly and immunocompromised patients worldwide.

67 Both the elderly and individuals with comorbidities are at increa

68 CR may require unique considerations for the elderly and other specific populations.

69 ty of COVID-19 lung disease is higher in the elderly and people with pre-existing co-morbidities.

70 why COVID-19 lung disease is greater in the elderly and people with pre-existing co-morbidities.

71 Health differences among the elderly and the role of medical treatments are topical i

72 developing severe illness especially in the elderly and those with concurrent illnesses.

73 re common neurodegenerative disorders of the elderly and, therefore, affect a growing number of patie

74 ost severely immunocompromised patients, the elderly, and children.

75 fections in infants, young children, and the elderly, and currently, no licensed vaccine exists.

76 diarrhea, especially in the very young, the elderly, and immunocompromised populations.

77 NR4A expression), observed previously in the elderly, and increased dendritic cell activation; (2) di

78 [2.10, 4.22] times more infectious than the elderly, and the former tend to be the main driver of su

79 onal expansion of mutated blood cells in the elderly, and this phenomenon is connected to susceptibil

80 However, the elderly are more fragile because of comorbidities, incre

81 of a cohort of 54 community-dwelling French elderly as well as their individual retronasal release o

82 apping versus nighttime sleep periods in the elderly, as well as the underlying autonomic and cardio-

83 whole genome sequence and phenotype of 2570 elderly Australians depleted for cancer, cardiovascular

84 No differences were found in the elderly between bivalirudin and heparin monotherapy rega

85 natal stroke is as frequent as stroke in the elderly, but many pathophysiological injury aspects are

86 function and delay cognitive decline in the elderly, but physical fitness (PF) could be a better pre

87 OPOA) is a common bone disease mostly in the elderly, but the relationship between Osteoporotic (OP)

88 tudied patients aged >=70 y from the ELCAPA (Elderly Cancer Patients) prospective open cohort (2007-2

89 Notably, elderly-centric programmes vaccinating from 65-75 years

90 rediction and BMD value prediction using 700 elderly Chinese Han subjects and 1,620 unrelated Chinese

91 s-sectional data from 10,837 middle-aged and elderly Chinese rural adults who completed a questionnai

92 ng behaviours and BMI in the middle-aged and elderly Chinese rural population.

93 In this elderly cohort of patients with type 2 diabetes and chro

94 adaptability, most B cells activated in the elderly cohort target highly conserved but less potent e

95 consistent difference between the young and elderly cohorts.

96 al elderly conditions), E2 (oral and gastric elderly conditions) and E3 (oral, gastric and intestinal

97 itions) and E3 (oral, gastric and intestinal elderly conditions)).

98 elderly in vitro digestion models: E1 (oral elderly conditions), E2 (oral and gastric elderly condit

99 tage to dementia, and 17 cognitively intact, elderly controls completed (18)F-ASEM PET.

100 ch subgroup to those from cognitively normal elderly controls.

101 eneral guidelines for the use of organs from elderly donors in liver transplantation.

102 the proportion of transplanted kidneys from elderly donors in the UK (10.7%) was 18 times greater th

103 tion, labile international normalized ratio, elderly, drugs/alcohol concomitantly) score was 3.0 +/-

104 ces between licensed vaccines used among the elderly during the 2018-2019 season.

105 with sepsis or noninfected patients who were elderly (eg, age >65 years) and had underlying comorbidi

106 s in Emergency Surgery Risk (POTTER) tool in elderly emergency surgery (ES) patients.

107 curate predictor of in-hospital mortality in elderly ES patients up to age 85 years.

108 mportant risk factor for RF mortality in the elderly, especially among persons with existing renal di

109 Elderly flossers had lower (mean, SE) %iCAL>=3 mm (38.2,

110 responding subjects) was associated with the elderly, FQREC, H30R, H30Rx, ST73, and specific VGs.

111 This study aimed to analyze the effect of elderly gastrointestinal (GI) conditions on proteolysis,

112 Proteolysis was highly affected by elderly GI alterations (p < 0.05) (50% of reduction comp

113 with UC diagnosed after the age of 65 years (elderly group, E-O) were identified and matched 1-1 acco

114 in children providing herd protection to the elderly group.

115 xposure on mortality and morbidity among the elderly ( >= 65 years of age) in Houston, Texas.

116 escence and reduced vaccine responses in the elderly (>70 yr).

117 t there was no significant difference in the elderly (>80 years: odds ratio, 1.07 [95% CI, 0.79-1.44]

118 Elderly had significantly lower heart rates (p < 0.05),

119 -alcoholic fatty liver disease (NAFLD) among elderly have not been well described.

120 renal failure (RF) among participants in the Elderly Health Service Cohort in Hong Kong, China, from

121 26 patients without such behaviours, and 31 elderly healthy controls.

122 containing lipoproteins isolated from BrM of elderly human donor eyes and found a unique proteome, di

123 1 in blood were increased in active, healthy elderly humans.

124 ring serum levels of 4,137 proteins in 5,438 elderly Icelanders, and identified 536 proteins associat

125 ally suboptimal; prioritized coverage of the elderly improves outcomes, while retaining resources for

126 For the elderly in China, increasing their total sleep, nighttim

127 p duration and depressive symptoms among the elderly in China.

128 oked fishes were in vitro subjected to three elderly in vitro digestion models: E1 (oral elderly cond

129 We included 3,007,620 elderly individuals aged >= 65 years who had at least on

130 une responses to influenza virus vaccines in elderly individuals are poorly adapted toward new antige

131 gree with the other methods and labeled most elderly individuals as Abeta-positive.

132 ing "negative" risk markers able to identify elderly individuals at low short-term risk for coronary

133 To limit overtreatment, elderly individuals at truly low risk need to be identif

134 rved subgingival bacterial patterns in these elderly individuals corroborated corresponding findings

135 We found a very high prevalence of falls in elderly individuals living in 'homes for the aged' in Hy

136 Thus, inhibiting p38 in elderly individuals rejuvenated their resolution respons

137 inistering an orally active p38 inhibitor to elderly individuals rescued TIM-4 expression, cleared ap

138 Reduced TIM-4 in elderly individuals was caused by an elevation in macrop

139 Elderly individuals with CAC = 0, CAC <=10, low galectin

140 , we propose that the diminished immunity in elderly individuals with CMV is due to alterations in ce

141 tivated influenza vaccines (IIVs) in adults, elderly individuals, and children.

142 lammatory onset is similar between young and elderly individuals, the resolution phase was substantia

143 of hospitalization and all-cause death among elderly individuals.

144 ata describing the periodontal microbiome in elderly individuals.

145 me sequences and phenotype data from healthy elderly individuals.

146 using longitudinal biomarkers in nondemented elderly individuals.

147 e a substantial disease burden in adults and elderly individuals.

148 s between dapagliflozin and placebo, even in elderly individuals.

149 ove iPS cell generation and wound healing in elderly individuals.

150 solution phase was substantially impaired in elderly individuals.

151 ts incident heart failure in community-based elderly individuals.

152 nts and young adults, although HL can affect elderly individuals.

153 n-inactive monoclonal antibodies (MAbs) from elderly individuals.

154 tory syndrome coronavirus 2 (SARS-CoV-2) are elderly, infection fatality rate (IFR) estimates for the

155 Outcomes of elderly intensive care patients evidenced independent se

156 Female and male very elderly intensive patients (VIPs) might differ in charac

157 hods (CCBM) suggest that colonization in the elderly is <5%.

158 sts that pneumococcal carriage in Portuguese elderly is approximately 10%, and unveiled a large pool

159 tudy of ticagrelor versus clopidogrel in the elderly is needed.

160 Preventing primary infections among the elderly is the most effective in countries with small ho

161 se burden in older children, adults, and the elderly is underappreciated.

162 isease, the leading cause of dementia in the elderly, is a neurodegenerative condition characterized

163 While AD is extremely prevalent in human elderly, it hardly occurs in non-primate mammals and eve

164 Particularly among the elderly, its prevalence and costs continue to rise, maki

165 the brains of young, middle aged, aged, and elderly male and female C57BL/6J mice.

166 oxygenation develop vascular complications; elderly males with comorbidities appear vulnerable.

167 AML is primarily diagnosed among the elderly (median 68 years old at diagnosis).

168 We analyzed data on elderly Medicare beneficiaries undergoing any of 4 elect

169 t aggressive neoplasm diagnosed primarily in elderly men.

170 apamycin rejuvenates the aged oral cavity of elderly mice, including regeneration of periodontal bone

171 Patients treated with CA were elderly, more often male, and had a history of diabetes,

172 Among the elderly (n = 8,510), sleeve was associated with lower 3-

173 oung adults (n = 22), cognitively unimpaired elderly (n = 89), and cognitively impaired (n = 65)] who

174 The elderly (n=1592) had more than twice the risk of all eve

175 8%, respectively, of patients in the neither elderly nor low-weight group (HR, 0.98 [CI, 0.65 to 1.47

176 eight group and standard dose in the neither elderly nor low-weight group).

177 0.82 [95% CI, 0.60 to 1.14]); in the neither elderly nor low-weight group, the efficacy end point occ

178 Our aim is to characterize UC in elderly-onset patients followed at our Inflammatory Bowe

179 atment for Mild Systolic Hypertension in the Elderly (OPTIMISE) study was a randomized, unblinded, no

180 rpes zoster ophthalmicus occurs primarily in elderly or immunocompromised individuals after reactivat

181 ticagrelor or prasugrel (reduced dose in the elderly or low-weight group and standard dose in the nei

182 In the elderly or low-weight group, Bleeding Academic Research

183 In the elderly or low-weight group, the efficacy end point occu

184 In elderly or low-weight patients with ACS, a reduced dose

185 Elderly organ transplant recipients have remained underr

186 Cross-sectionally, elderly participants also showed worse attention perform

187 Thirty-one healthy elderly participants performed a change-detection task w

188 In a subgroup analysis, elderly patients (>=65 years old) treated with laparosco

189 Extraintestinal manifestations were lower in elderly patients (9.6% vs 19.2%, p = 0.061).

190 y, as with the wider population, outcomes in elderly patients admitted to ICU are improving over time

191 g in the establishment of bile stream in the elderly patients and the ones who are not good candidate

192 ot always benefit from treatment, especially elderly patients and those with baseline TSH levels belo

193 ) infection disproportionally affects frail, elderly patients and those with multiple chronic comorbi

194 ominantly hospitalized New York City cohort, elderly patients are at highest mortality risk.

195 Elderly patients are at particularly increased cardiovas

196 as recently received increased attention, as elderly patients are at substantially elevated risk for

197 Large prognostic studies evaluating elderly patients are currently lacking.

198 Elderly patients had greater imaging utilization, hospit

199 Predicting outcomes in elderly patients has been historically challenging and P

200 Over the past two decades, elderly patients have been more commonly admitted to ICU

201 indicate caution against the use of LCCBs in elderly patients or patients with advanced hypertension

202 grel versus a standard dose of ticagrelor in elderly patients or those with a low body weight present

203 nificant cause of morbidity, particularly in elderly patients or those with immune deficiency or unde

204 s) longitudinally collected from a cohort of elderly patients undergoing major surgery, comparing sam

205 harmacokinetic parameters in non-elderly and elderly patients were similar.

206 , surgical hip fractures) remains unclear in elderly patients who are suspected to have such fracture

207 to standard of care secondary prophylaxis in elderly patients who have survived an AMI would reduce t

208 In a cohort of elderly patients with a high atherosclerotic burden, fam

209 Conclusion Elderly patients with acute hip pain and negative or equ

210 rans retinoic acid (ATRA) in treatment-naive elderly patients with acute myeloid leukemia (AML).

211 Elderly patients with acute myocardial infarction underg

212 This study examines elderly patients with appendicitis, a common condition t

213 as frequently observed among immunocompetent elderly patients with comorbidities or severe concomitan

214 tensified Versus Standard Medical Therapy in Elderly Patients With Congestive Heart Failure; n=431),

215 To address this, we examined two elderly patients with duplication of PLP1 in whom the ov

216 lied a retrospective cohort design on 29,095 elderly patients with end-stage renal disease who died b

217 tate, the disease had its greatest impact on elderly patients with medical comorbidities.

218 Ticagrelor use among elderly patients with MI was associated with higher risk

219 A prespecified subgroup analysis of elderly patients with myocardial infarction (>=75 years)

220 p analysis of the VALIDATE-SWEDEHEART trial, elderly patients with myocardial infarction had a highly

221 patients with mucinous pancreatic cysts, and elderly patients with new-onset diabetes.

222 ate the frequency of systemic drugs taken by elderly patients with or without periodontitis and the p

223 esponses; and acceptable safety in primarily elderly patients with R/M cSCC, supporting its use in cl

224 t detect reduction in clinical events in our elderly patients with recent AMI who were treated with 1

225 fficacy comparable to that of doxorubicin in elderly patients with STS and offers superior tolerabili

226 Off-Pump Coronary Artery Bypass Grafting in Elderly Patients) revealed no significant difference in

227 In this natural experiment involving 329,976 elderly patients, exposure to appendectomy surgery and a

228 or cost per bed day are made, especially for elderly patients, the cost of EGS will rise dramatically

229 Elderly patients, those with established cardiovascular

230 y of radiographically occult hip fracture in elderly patients, to define the higher-risk subpopulatio

231 tic options and more aggressive treatment of elderly patients, will have major impact on the future n

232 ction (NSTEMI), but the trials excluded very elderly patients.

233 morbidity and mortality risks, especially in elderly patients.

234 tic valve replacement and lung transplant in elderly patients.

235 Mortality (p < 0.0005) was higher in elderly patients.

236 nd treatments for end-stage liver disease in elderly patients.

237 e healing and increased rates of nonunion in elderly patients.

238 lves (P = 0.005) and whose had a presence of elderly people in the household (P = 0.006).

239 Major increases in the proportion of elderly people in the population are predicted worldwide

240 an immunodeficiency virus (HIV) diagnosis in elderly people living with HIV (PLWH).

241 Apart from decreased hearing sensitivity, elderly people often suffer from a reduced ability to co

242 The coresidence patterns of elderly persons in Africa and parts of Asia increase the

243 Current vaccination strategies prioritizing elderly persons may be less effective than believed at r

244 findings may partly explain why smokers and elderly persons with compromised surfactant function are

245 reduced hospitalizations or mortality among elderly persons.

246 reduces hospitalizations and mortality among elderly persons.

247 oes not seem to be a criterion for selecting elderly PLWH at risk of MM.

248 life-threating illness, particularly in the elderly population and individuals with comorbid conditi

249 lence of subclinical AF in a community-based elderly population and to characterize subclinical AF an

250 cline is becoming increasingly urgent as the elderly population continues to grow.

251 ategies Addressing the Specific Needs of the Elderly Population for Healthy Aging in Europe (NU-AGE)]

252 Incidence of ulcerative colitis (UC) in elderly population is increasing because of ageing and b

253 and the risk of having short telomeres in an elderly population of the Seguimiento Universidad de Nav

254 of a million people globally, mainly in the elderly population with preexisting pathologies.

255 ) is one of the major health problems in the elderly population, causing significant morbidity and mo

256 he prevalence of mitral regurgitation in the elderly population, however, almost half of patients ide

257 s dermatitis (SD) is a common disease in the elderly population, with pruritus being one of the troub

258 propriateness of a treat-all approach in the elderly population.

259 iversal risk-based statin eligibility in the elderly population.

260 dings suggest excess mortality among certain elderly populations in Houston who are likely exposed to

261 and death, especially in the very young and elderly populations.

262 e compared survival and clinical outcomes in elderly recipients with low immunological risk according

263 In elderly recipients, ATG does not lead to poorer outcomes

264 This effect was reduced for the elderly, replicating an earlier finding.

265 However, in America today, the elderly report less pain than those in midlife.

266 While the elderly require additional resources to disambiguate deg

267 Elderly residents (>= 65 years old) with a suspected UTI

268 r association with visual impairment (VI) in elderly residents in 'homes for the aged' in Hyderabad,

269 Validation of the Elderly Risk Assessment index in the emergency departmen

270 ividuals of the Activity and Function in the Elderly study using confounder-adjusted Cox proportional

271 We identified 1,230 elderly subjects (aged >=50 years) with an average of 4.

272 Shingrix protection retains its efficacy in elderly subjects (individuals 80 years of age and older)

273 Finally, elderly subjects have lower PHD1 levels and LRS activity

274 response shared across multiple diseases in elderly subjects that is distinct from that in young/mid

275 icipants consisting of 17 cognitively normal elderly subjects, 45 patients with Parkinson's disease w

276 e follow-up period in 8 out of the 9 control elderly subjects.

277 obstructive pulmonary disease, hypertension, elderly, systolic heart failure, thyroid disease), and C

278 o understand retronasal aroma release in the elderly that could contribute to the development of pers

279 to the dysfunctional immune response of the elderly to the vaccine against influenza.

280 munosuppression in the growing population of elderly transplant recipients.

281 fferential abundance in stool samples of 666 elderly TREND (Tubingen Evaluation of Risk Factors for E

282 hase III European Mantle Cell Lymphoma (MCL) Elderly trial (ClinicalTrials.gov identifier: NCT0020920

283 he ASPREE (Aspirin in Reducing Events in the Elderly) trial.

284 ndex (3.8 vs 1.6, p < 0.0005) was higher for elderly UC patients.

285 ge prevalence and serotypes among Portuguese elderly using qPCR and compared results with those obtai

286 e associated with the protection observed in elderly vaccinees following Shingrix vaccination is rele

287 approximately one-third of the 89 adult and elderly vaccinees.

288 cal classification of cognitively unimpaired elderly versus Alzheimer disease dementia, ROC curves ba

289 he relationship between CH and anemia of the elderly, we explored the landscape and dynamics of CH in

290 Malnutrition is a serious problem in the elderly while understanding flavour perception could be

291 ll-characterized cohort of clinically normal elderly who were followed longitudinally.

292 ease for all adults; importantly, tomorrow's elderly will be sicker than today's elderly, with potent

293 D) is a common multifactorial disease in the elderly with a prominent genetic basis.

294 impact of renal transplantation (RT) in the elderly with many comorbid conditions is a matter of con

295 The OMEMI trial (Omega-3 Fatty acids in Elderly with Myocardial Infarction) is an investigator-i

296 morrow's elderly will be sicker than today's elderly, with potentially serious implications for healt

297 s assisted their descendants, more recently, elderly withdraw from work and require assistance as wel

298 , which is routinely found in mammography of elderly women, could be predictive of coronary artery ca

299 auses of death and major disabilities in the elderly worldwide.

300 common cause of incurable vision loss in the elderly worldwide.