ライフサイエンスコーパス: electron cryomicroscopy

1 with its nucleotide exchange factor eIF2B by electron cryomicroscopy.

2 membrane and analyze its oligomeric state by electron cryomicroscopy.

3 n15 (epsilon15) particle, by single-particle electron cryomicroscopy.

4 hree-dimensional reconstructions obtained by electron cryomicroscopy.

5 acillus stearothermophilus taken by low-dose electron cryomicroscopy.

6 d empty CPV determined at 13-A resolution by electron cryomicroscopy.

7 virus type 1 (HSV-1) B capsid, determined by electron cryomicroscopy.

8 een determined at 8.5 angstrom resolution by electron cryomicroscopy.

9 were analyzed using biochemical methods and electron cryomicroscopy.

10 the scaffolding protein have been studied by electron cryomicroscopy.

11 ist-bound GluN1-2D NMDARs by single-particle electron cryomicroscopy.

12 S)-stabilized PfAct1 filaments determined by electron cryomicroscopy.

13 es of interest, and imaged the vesicles with electron cryomicroscopy.

14 .1 angstrom-resolution using single particle electron cryomicroscopy.

15 um thermophilum, obtained by single-particle electron cryomicroscopy.

16 ermined its structure to 3.6-A resolution by electron cryomicroscopy.

17 c using single-particle electron cryomicroscopy.

18 of SERCA in the presence of wild-type SLN by electron cryomicroscopy.

19 esolutions between 2.5 and 5.0 A by means of electron cryomicroscopy.

20 ubiquitylated nucleosome, and validate it by electron cryomicroscopy.

21 of EBOV, both determined by single-particle electron cryomicroscopy.

22 tion of 3.8 A, determined by single-particle electron cryomicroscopy.

23 nward-facing conformation by single-particle electron cryomicroscopy.

24 osin at a resolution of 6.5 A, determined by electron cryomicroscopy.

25 s confidence in a structure determined using electron cryomicroscopy.

26 Here, we combined electron cryomicroscopy, 3D reconstruction, and integrat

27 Structural characterization using electron cryomicroscopy allowed us to resolve apo-state

28 implex virus type 1 virions were examined by electron cryomicroscopy, allowing the three-dimensional

29 Electron cryomicroscopy analysis demonstrated that the s

30 We used electron cryomicroscopy and 3D image reconstruction to e

31 Using electron cryomicroscopy and angular reconstitution techn

32 We have used electron cryomicroscopy and angular reconstitution to vi

33 We used electron cryomicroscopy and antibody labeling to show th

34 We have used electron cryomicroscopy and computer image processing to

35 Electron cryomicroscopy and computer reconstruction reve

36 orbol-13-acetate to obtain HHV-8 capsids for electron cryomicroscopy and computer reconstruction.

37 nd inside constricting liposomes by means of electron cryomicroscopy and cryotomography.

38 plied X-ray crystallography, single-particle electron cryomicroscopy and electrophysiology to rat NMD

39 We have used electron cryomicroscopy and helical reconstruction to id

40 We have used electron cryomicroscopy and helical reconstruction to id

41 construction of G2-6:F-actin was obtained by electron cryomicroscopy and helical reconstruction.

42 gal partitivirus, determined in this case by electron cryomicroscopy and homology modeling.

43 We used electron cryomicroscopy and icosahedral image analysis t

44 In this study, we used transmission electron cryomicroscopy and icosahedral image reconstruc

45 Using electron cryomicroscopy and icosahedral image reconstruc

46 Electron cryomicroscopy and icosahedral reconstruction a

47 Using electron cryomicroscopy and icosahedral reconstruction o

48 Recent developments in electron cryomicroscopy and image analysis have made it

49 Electron cryomicroscopy and image analysis of New World

50 id isolated from VEEV has been determined by electron cryomicroscopy and image reconstruction and rep

51 Examination of the VLPs by electron cryomicroscopy and image reconstruction at 15.4

52 e was determined to 12-A resolution by using electron cryomicroscopy and image reconstruction techniq

53 We used electron cryomicroscopy and image reconstruction to dete

54 erminus of VP2 within the core, we have used electron cryomicroscopy and image reconstruction to dete

55 We have used electron cryomicroscopy and image reconstruction to obta

56 e 25-A structure of VEE virus, obtained from electron cryomicroscopy and image reconstruction.

57 d barrel clathrin coat at 21 A resolution by electron cryomicroscopy and of the clathrin terminal dom

58 atelet integrin alpha(IIb)beta(3) derived by electron cryomicroscopy and single particle image recons

59 annel (also known as RyR1) was determined by electron cryomicroscopy and single particle reconstructi

60 ith an ATP-ADP mixture at 11 A resolution by electron cryomicroscopy and single-particle averaging of

61 ion of human fatty acid synthase obtained by electron cryomicroscopy and single-particle image proces

62 -density lipoprotein (LDL) was obtained from electron cryomicroscopy and single-particle image recons

63 By the use of electron cryomicroscopy and single-particle reconstructi

64 te receptor (InsP3R1) has been determined by electron cryomicroscopy and single-particle reconstructi

65 We have used electron cryomicroscopy and three-dimensional image reco

66 We used electron cryomicroscopy and three-dimensional image reco

67 o directly locate the KSHV SCP, we have used electron cryomicroscopy and three-dimensional reconstruc

68 ime allowing direct structure comparisons by electron cryomicroscopy and three-dimensional reconstruc

69 Electron cryomicroscopy and three-dimensional reconstruc

70 protein (FKBP12), have been characterized by electron cryomicroscopy and three-dimensional reconstruc

71 structures of Tula hantavirus virions using electron cryomicroscopy and tomography.

72 process, consistent with recent models from electron cryomicroscopy and X-ray crystallography.

73 of DNA packing in HCMV and HSV-1 virions by electron-cryomicroscopy and image processing.

74 ng time-resolved phosphorescence anisotropy, electron cryomicroscopy, and all-atom molecular dynamics

75 We used a combination of bioinformatics, electron cryomicroscopy, and biochemical techniques to i

76 Here we demonstrate using genomic analysis, electron cryomicroscopy, and image reconstruction that t

77 Combining X-ray crystallography, electron cryomicroscopy, and in silico predictions, we h

78 ysis, x-ray crystallography, single-particle electron cryomicroscopy, and molecular dynamics simulati

79 n, quantitative agarose gel electrophoresis, electron cryomicroscopy, and nuclease digestion.

80 mensional crystals of CydDC were analyzed by electron cryomicroscopy, and the protein was shown to be

81 these structures, X-ray crystallography and electron cryomicroscopy are capable of determining struc

82 we are now firmly within the "atomic age" of electron cryomicroscopy, as these studies can reveal ato

83 Furthermore, by using electron cryomicroscopy, as well as penton- and protein

84 ex from Neurospora crassa by single-particle electron cryomicroscopy at 3.3 angstrom resolution, show

85 type 1 RyR (RyR1), solved by single-particle electron cryomicroscopy at an overall resolution of 4.8

86 formed by Abeta(1-40) peptide, determined by electron cryomicroscopy at approximately 8-A resolution.

87 ) supercomplex determined by single-particle electron cryomicroscopy at near-atomic to sub-nanometre

88 m falciparum actomyosin system determined by electron cryomicroscopy at the end of the powerstroke (R

89 the structure of a K. lactis CBF3 complex by electron cryomicroscopy at ~4 angstrom resolution and co

90 n of the Pr-minus and wild-type B capsids by electron cryomicroscopy, at an unprecedented 12.5-angstr

91 We resolved electron cryomicroscopy atomic structures of Pf4 with an

92 These observations support an electron cryomicroscopy-based structural model on which

93 res of many proteins cannot be determined by electron cryomicroscopy because the individual proteins

94 Electron cryomicroscopy can yield near-atomic resolution

95 Electron cryomicroscopy can, in principle, determine the

96 biochemical reconstitutions, single-particle electron cryomicroscopy, cross-linking mass spectrometry

97 mbrane protein complex have been analysed by electron cryomicroscopy (cryo EM).

98 Our single-particle electron cryomicroscopy (cryo-EM) analyses demonstrate t

99 We report here single particle electron cryomicroscopy (cryo-EM) analysis of the bovine

100 A protease with its transmembrane domains by electron cryomicroscopy (cryo-EM) and atomic structure f

101 We used electron cryomicroscopy (cryo-EM) and image analysis to

102 Recently published electron cryomicroscopy (cryo-EM) and X-ray crystallogra

103 omer boundaries in a subnanometer-resolution electron cryomicroscopy (cryo-EM) density map.

104 large high-symmetry viruses, single-particle electron cryomicroscopy (cryo-EM) has achieved the deter

105 Electron cryomicroscopy (cryo-EM) has been used to deter

106 Single-particle electron cryomicroscopy (cryo-EM) has led to a revolutio

107 Electron cryomicroscopy (cryo-EM) has revolutionised str

108 Here, we present electron cryomicroscopy (cryo-EM) maps showing that VAT

109 Here we report the electron cryomicroscopy (cryo-EM) reconstruction of the

110 Here, we present a single particle electron cryomicroscopy (cryo-EM) reconstruction of yeas

111 Here, we report a electron cryomicroscopy (cryo-EM) structure of the abund

112 Here we present 3 to 3.5 angstrom resolution electron cryomicroscopy (cryo-EM) structures comprising

113 Electron cryomicroscopy (cryo-EM) structures of apo and

114 We report the electron cryomicroscopy (cryo-EM) structures of the nati

115 Single-particle electron cryomicroscopy (cryo-EM) structures of the supe

116 Here, we report electron cryomicroscopy (cryo-EM) structures of VWF tubu

117 We used electron cryomicroscopy (cryo-EM) to determine a structu

118 Here, we have used single-particle analysis electron cryomicroscopy (cryo-EM) to determine structure

119 Here, we used electron cryomicroscopy (cryo-EM) to determine the struc

120 ity called the "stutter." Here, we have used electron cryomicroscopy (cryo-EM) to determine the struc

121 tate optimization of lead compounds, we used electron cryomicroscopy (cryo-EM) to determine the struc

122 We have used electron cryomicroscopy (cryo-EM) to examine the filamen

123 captured images of this transient process by electron cryomicroscopy (cryo-EM) to reveal the structur

124 Using electron cryomicroscopy (cryo-EM) we have structurally c

125 ormed mass-per-length (MPL) measurements and electron cryomicroscopy (cryo-EM) with 3D reconstruction

126 Electron cryomicroscopy (cryo-EM) yields images of macro

127 microscopy of cryogenically cooled samples (electron cryomicroscopy (cryo-EM)).

128 The structures were determined using electron cryomicroscopy (cryo-EM), and the three-dimensi

129 nt an integrated approach of single-particle electron cryomicroscopy (cryo-EM), computational modelin

130 With single-particle electron cryomicroscopy (cryo-EM), it is possible to vis

131 Our study, using single-particle electron cryomicroscopy (cryo-EM), reveals the structure

132 Using electron cryomicroscopy (cryo-EM), we imaged an in vitro

133 Using electron cryomicroscopy (cryo-EM), we present a reconstr

134 ngle-particle analysis of images obtained by electron cryomicroscopy (cryo-EM).

135 rotein in the presence of RNA, determined by electron cryomicroscopy (cryo-EM).

136 n complex with MatP and DNA as determined by electron cryomicroscopy (cryo-EM).

137 uman CFTR without nucleotides, determined by electron cryomicroscopy (cryo-EM).

138 A recent electron-cryomicroscopy (cryo-EM) model of the slow-seve

139 infectious rotavirus particle determined by electron cryomicroscopy (cryoEM) and single-particle ana

140 FcRY's pH-dependent binding mechanism using electron cryomicroscopy (cryoEM) and small-angle X-ray s

141 r Epinephelus malabaricus, was determined by electron cryomicroscopy (cryoEM) and three-dimensional r

142 f antigen-antibody complexes.Single-particle electron cryomicroscopy (cryoEM) can circumvent some of

143 possible to thin and vitrify a specimen for electron cryomicroscopy (cryoEM) faster than proteins di

144 Complementing this work, electron cryomicroscopy (cryoEM) has provided relatively

145 Electron cryotomography (cryoET), an electron cryomicroscopy (cryoEM) modality, has changed o

146 We have combined image reconstructions from electron cryomicroscopy (cryoEM) of bovine papillomaviru

147 We report here low-resolution (20 A) electron cryomicroscopy (cryoEM) structures of this gp14

148 a template:primer RNA duplex, determined by electron cryomicroscopy (cryoEM) to a resolution of 2.5

149 We then used electron cryomicroscopy (cryoEM) to determine structures

150 We have determined by electron cryomicroscopy (cryoEM), at about 11 A resoluti

151 Using single-particle electron cryomicroscopy (cryoEM), we have solved the str

152 principle, be determined by single-particle electron cryomicroscopy (cryoEM).

153 sion electron microscopy (TEM), transmission electron cryomicroscopy (cryoTEM), and thermogravimetric

154 ific structural information that complements electron cryomicroscopy data and defines targets and str

155 e for near-atomic to high-resolution (3-5 A) electron cryomicroscopy data evaluation.

156 NMR and electron cryomicroscopy data have been used as restraint

157 Fitting of the modeled PapA subunit into the electron cryomicroscopy data provides a detailed view of

158 procapsid and infectious virion derived from electron cryomicroscopy density maps determined at 3.8-

159 to the previously determined 25-A-resolution electron cryomicroscopy density maps of HAstV allowed us

160 igh-resolution, all-atom protein models from electron cryomicroscopy density maps.

161 the truncated E2 core, using low-resolution electron cryomicroscopy density maps.

162 s complex I, determined to 5-A resolution by electron cryomicroscopy, described the structure of the

163 Using electron cryomicroscopy difference mapping, we have iden

164 study, we analyzed E1HT by a combination of electron cryomicroscopy, electron crystallography of neg

165 of TRPV1 determined by using single-particle electron cryomicroscopy exhibits fourfold symmetry and c

166 rus structure and reflect the growing use of electron cryomicroscopy for atomic modeling of protein f

167 nd to F-actin, highlighting the potential of electron cryomicroscopy for structure-based drug design.

168 Electron cryomicroscopy had previously given detailed ri

169 Advances in single-particle electron cryomicroscopy have recently revealed details o

170 Despite a molecular weight of only 24 kDa, electron cryomicroscopy illustrated a remarkable level o

171 des and phases can be computed directly from electron cryomicroscopy images.

172 ted mutagenesis, ultrastructural analysis by electron cryomicroscopy, immunocytochemistry, and molecu

173 To this end we have used single-particle electron cryomicroscopy in combination with cross-linkin

174 Electron cryomicroscopy in conjunction with single-parti

175 Here, we provide evidence, using electron cryomicroscopy, in conjunction with light-scatt

176 e of the alpha(V)beta(3) ectodomain into the electron cryomicroscopy map of alpha(IIb)beta(3) require

177 An electron cryomicroscopy map of PsV-F shows that the diso

178 nt and its modeling into an 8.5 A resolution electron cryomicroscopy map of the HSV-1 capsid.

179 e, allowing us to obtain a ~3.9-A resolution electron cryomicroscopy map of the VO complex and build

180 no acid side chains were identified from the electron cryomicroscopy map.

181 Here we present detailed 3D electron cryomicroscopy maps of archaeal S-layers from 3

182 rgent dodecyl maltoside, which is visible in electron cryomicroscopy maps.

183 Here, using modern electron cryomicroscopy methods, we investigate the stru

184 Utilizing novel electron cryomicroscopy methods, we solved structures of

185 ion images of assembled coats, determined by electron cryomicroscopy, now provide the information nec

186 cherichia coli multidrug transporter EmrE by electron cryomicroscopy of 2D crystals, including data t

187 ce at subnanometre resolution, obtained from electron cryomicroscopy of coats assembled in vitro.

188 Here, using electron cryomicroscopy of EmrE two-dimensional crystals

189 Electron cryomicroscopy of rotor complexes of the Salmon

190 Electron cryomicroscopy of S1-bound actin filaments, tog

191 luenza neuraminidase, has been determined by electron cryomicroscopy of single particles and image an

192 synthase at approximately 18 A resolution by electron cryomicroscopy of single particles in amorphous

193 P synthase from bovine heart mitochondria by electron cryomicroscopy of single particles.

194 The structure has been determined by electron cryomicroscopy of the adenosine triphosphate (A

195 ly 12 A resolution image reconstruction from electron cryomicroscopy of trypsin-primed virions shows

196 ed in icosahedral image reconstructions from electron cryomicroscopy of trypsinized rotavirus virions

197 eromyosin suitable for structural studies by electron cryomicroscopy of unstained, frozen-hydrated sp

198 e here a structure at 3.9 A resolution, from electron cryomicroscopy, of Pepino mosaic virus (PepMV),

199 ation of the envelope glycoprotein either by electron cryomicroscopy or X-ray crystallography.

200 sualized the double-layered COPII coat using electron cryomicroscopy, providing insight into how coat

201 In this work, we show the electron cryomicroscopy reconstruction of a bacterial dy

202 Here we present the electron cryomicroscopy reconstruction of an ATP-activat

203 Here, we present the electron cryomicroscopy reconstruction of the Saccharomy

204 , determined by fitting the subunit into the electron cryomicroscopy reconstruction of the virus, ide

205 e cleavage site, did not mature at pH 5, and electron cryomicroscopy reconstruction showed that it wa

206 Here, we present electron cryomicroscopy reconstructions of dodecameric y

207 Here we present the 3D electron cryomicroscopy reconstructions of the major Ufd

208 were clearly visible and well ordered in the electron cryomicroscopy reconstructions of TR TLPs, they

209 Using the low-resolution maps from electron cryomicroscopy reconstructions, the simulations

210 cofilactin filament structures determined by electron cryomicroscopy reveal how cofilin enhances the

211 FTCD structure by X-ray crystallography and electron cryomicroscopy revealed that the eight subunits

212 Electron cryomicroscopy revealed two major particle popu

213 Analysis by electron cryomicroscopy reveals a triangular shaped olig

214 The virion structure, determined by electron cryomicroscopy, reveals that the bulk of the ou

215 ensional structures of full and empty CPV by electron cryomicroscopy show identical outer shells but

216 Both conventional and electron cryomicroscopy showed clearly that the ribbons

217 High resolution electron cryomicroscopy showed that one such peptide bin

218 Three-dimensional structural studies using electron cryomicroscopy showed that the binding of one F

219 Electron cryomicroscopy shows how the Vma12-22p complex

220 Our approach combines electron cryomicroscopy, site-directed mutagenesis, homo

221 rientation distribution of a single-particle electron cryomicroscopy specimen limits the resolution o

222 s has been determined to 3.4 A, using a 22-A electron cryomicroscopy structure as a phasing model.

223 describe a 4.2-A resolution single-particle electron cryomicroscopy structure of complex I from Bos

224 re, we report a 3.6-A helical reconstruction electron cryomicroscopy structure of four-stranded mini

225 Here, we improved upon our previous electron cryomicroscopy structure of Salmonella bacterio

226 uman aminopeptidase N (hAPN), as well as the electron cryomicroscopy structure of the 229E S-protein.

227 Here, we report an electron cryomicroscopy structure of the Caulobacter cre

228 In this study, we report the electron cryomicroscopy structure of the D. radiodurans

229 Here, we present an electron cryomicroscopy structure of the MDA phage, show

230 ur knowledge, near-atomic (4.7 A) resolution electron cryomicroscopy structure of the tetrameric mamm

231 nal and visualization analysis from the 8.5A electron cryomicroscopy structure of the whole capsid.

232 binding S-layer array with a single-particle electron cryomicroscopy structure, revealing detailed fe

233 , we present high-resolution single-particle electron cryomicroscopy structures of an ABC transporter

234 Here, we present electron cryomicroscopy structures of CLC-7 in occluded

235 Here, we solved electron cryomicroscopy structures of Escherichia coli 7

236 e aminoglycosides, determine high-resolution electron cryomicroscopy structures of m(1)A1408-modified

237 Our mutational analysis, based on the electron cryomicroscopy structures of monomeric Pol I al

238 virions, the available crystallographic and electron cryomicroscopy structures of NV have not reveal

239 P22 coat protein lattice, we have determined electron cryomicroscopy structures of scaffolding-contai

240 Here, we present electron cryomicroscopy structures of TasA fibres, which

241 Here we report high-resolution electron cryomicroscopy structures of truncated and full

242 as advanced techniques, such as transmission electron cryomicroscopy, synchrotron-based X-ray absorpt

243 scattering (SEC-MALS) and images obtained by electron cryomicroscopy that McrB exists as a hexamer in

244 Here we show by electron cryomicroscopy that YnaI has an extended sensor

245 We have determined by electron cryomicroscopy the structure of the vesicular s

246 In electron cryomicroscopy, there have been numerous attemp

247 tif with nanogold and used three-dimensional electron cryomicroscopy to compare images of microtubule

248 Here, we have used electron cryomicroscopy to determine 12-A-resolution str

249 We use electron cryomicroscopy to determine a 3.2 angstrom heli

250 Here we describe the use of electron cryomicroscopy to determine how VP4 performs th

251 We used electron cryomicroscopy to determine structures of ArfA

252 hannel called "portal protein." We have used electron cryomicroscopy to determine the structure of ba

253 Here we use electron cryomicroscopy to determine the structure of th

254 We have used electron cryomicroscopy to determine the structures of r

255 emerging technique of Zernike phase-contrast electron cryomicroscopy to enhance the image contrast of

256 We have used three-dimensional electron cryomicroscopy to gain insight into the structu

257 tional constraints from linear dichroism and electron cryomicroscopy to obtain the allowed orientatio

258 Here we use electron cryomicroscopy to solve the structure of the co

259 We have used single-particle electron cryomicroscopy to study the multilayer structur

260 We have used electron cryomicroscopy to study tubular particles extra

261 Here we used electron cryomicroscopy together with computer-based doc

262 Here, electron cryomicroscopy together with computer-based doc

263 A three-dimensional reconstruction from electron cryomicroscopy was used as a molecular replacem

264 Using electron cryomicroscopy, we calculated difference maps b

265 Using electron cryomicroscopy, we captured the structure of th

266 Using electron cryomicroscopy, we determined a 3.5-angstrom-re

267 Using electron cryomicroscopy, we determined the molecular str

268 Using electron cryomicroscopy, we determined the three-dimensi

269 Here, using electron cryomicroscopy, we have determined the structur

270 Using electron cryomicroscopy, we have determined the three-di

271 By using recent advances in single-particle electron cryomicroscopy, we have solved the structure of

272 Using electron cryomicroscopy, we present reconstructions of f

273 to a reconstruction of the whole virion from electron cryomicroscopy, we propose that each sigma3 sub

274 Also using electron cryomicroscopy, we reconstruct ParM doublets fo

275 d fully defined chromatin arrays obtained by electron cryomicroscopy, we report a linker histone-depe

276 Using electron cryomicroscopy, we show here that ATP binding o

277 ined under various chemical conditions using electron cryomicroscopy, we show here that the viral gen

278 report the structures of PaaZ determined by electron cryomicroscopy with and without bound ligands.

279 Subsequent single-particle electron cryomicroscopy yielded a reconstruction at appr