ライフサイエンスコーパス: electron transport chain

1 ochrome c oxidoreductase (complex III of the electron transport chain).

2 e Krebs cycle and is located upstream of the electron transport chain.

3 tion of reactive oxygen species (ROS) by the electron transport chain.

4 rial respiration due to lack of NADH for the electron transport chain.

5 dogenous superoxide (O2(*-)) produced in the electron transport chain.

6 to water without involving cytochrome-linked electron transport chain.

7 by slowing respiration at the mitochondrial electron transport chain.

8 participating in redox reactions within the electron transport chain.

9 t characterized complex of the mitochondrial electron transport chain.

10 rough complex I and II, respectively, of the electron transport chain.

11 bition of Complex I within the mitochondrial electron transport chain.

12 fer of electrons to O2 via the mitochondrial electron transport chain.

13 lectron leak occurring at complex III of the electron transport chain.

14 of cytochrome c oxidase in the mitochondrial electron transport chain.

15 lates with the redox state of photosynthetic electron transport chain.

16 inant, physiologically relevant state of the electron transport chain.

17 rease in expression of genes involved in the electron transport chain.

18 y and nanomolar potency as complex II of the electron transport chain.

19 buildup of energy metabolites that feed the electron transport chain.

20 of a reduction signal in the photosynthetic electron transport chain.

21 mobile electron carriers in the respiratory electron transport chain.

22 +)), a neurotoxin that inhibits complex I of electron transport chain.

23 nit of complex I (NADH dehydrogenase) in the electron transport chain.

24 th the reducing equivalents generated by the electron transport chain.

25 with decreased activity of the mitochondrial electron transport chain.

26 respiration at the level of complex I of the electron transport chain.

27 ofactors and catalysts in the photosynthetic electron transport chain.

28 esis with maintaining the redox poise of the electron transport chain.

29 olony variants (SCVs) that lack a functional electron transport chain.

30 ogressively compromised the integrity of the electron transport chain.

31 udy elements of the organohalide respiratory electron transport chain.

32 dicative of an impaired redox balance of the electron transport chain.

33 in production in the absence of a functional electron transport chain.

34 nophoric uncoupling and/or inhibition of the electron transport chain.

35 a rate-limiting enzyme of the mitochondrial electron transport chain.

36 es, including disorders of the mitochondrial electron transport chain.

37 iration in an interlinked thylakoid membrane electron transport chain.

38 wo benzoquinones as electron carriers in the electron transport chain.

39 cluding NADPH oxidases and the mitochondrial electron transport chain.

40 Krebs enzyme aconitase and complex IV of the electron transport chain.

41 production by complex I of the mitochondrial electron transport chain.

42 , including the tricarboxylic acid cycle and electron transport chain.

43 itochondrial translation and assembly of the electron transport chain.

44 on required to support the NQ-driven aerobic electron transport chain.

45 ining the ability to oxidize NADH within the electron transport chain.

46 srupt particular iron-sulfur proteins of the electron transport chain.

47 drial proton uncouplers or inhibitors of the electron transport chain.

48 termined to interfere with the mycobacterial electron transport chain.

49 itochondrial translation and assembly of the electron transport chain.

50 reduced forms residing in the mitochondrial electron-transport chain.

51 le inner-membrane potential generated by the electron-transport chain.

52 ed genes and highlighted re-modelling of the electron transport chains.

53 ified the proteins involved in the TM and PM electron transport chains.

54 rticularly at the level of complex II of the electron transport chain (2.2-fold increase; P < 0.01).

55 te dehydrogenase activity (complex II of the electron transport chain); 3) increase catalase activity

56 Complex I (CI) of the electron transport chain, a large membrane-embedded NADH

57 n is associated with a dramatic reduction in electron transport chain abundance.

58 Inhibition of complex I of the mitochondrial electron transport chain activated AMPK and inhibited Kv

59 ial ultrastructure, impaired respiration and electron transport chain activities, and persistent prot

60 Biochemically mutant mice showed impaired electron transport chain activity and accumulated autoph

61 sue of Cell, Bonnay et al. identify enhanced electron transport chain activity as a critical determin

62 cid oxidation, reduced complex I- associated electron transport chain activity, and ATP depletion.

63 n a reduction in mitochondrial RNAs, reduced electron transport chain activity, and reduced ATP level

64 AKAP1-RNA interactions reduces mitochondrial electron transport chain activity.

65 IMM constriction requires electron transport chain activity.

66 ion in mitochondria, including modulation of electron transport chain activity.

67 bioenergetic target for the Krebs cycle, the electron transport chain, also becomes altered, generati

68 n because it encodes protein subunits of the electron transport chain and a full set of transfer and

69 due to a coupling between the photosynthetic electron transport chain and a plastidial hydrogenase.

70 oxide is known to inhibit complex IV of the electron transport chain and aconitase of the Krebs cycl

71 s the activity of both complex II/III of the electron transport chain and ATP synthase.

72 capacity and efficiency of the mitochondrial electron transport chain and ATP synthesis.

73 synthesis while maintaining a redox-balanced electron transport chain and avoiding excessive reactive

74 ylococcus aureus typically lack a functional electron transport chain and cannot produce virulence fa

75 as a consequence of subunit function in the electron transport chain and citric acid cycle, respecti

76 a are known primarily as the location of the electron transport chain and energy production in cells.

77 lti-subunit complex III of the mitochondrial electron transport chain and is involved in the electron

78 ostharvest storage through the mitochondrial electron transport chain and NADPH oxidase, respectively

79 is critically dependent on the mitochondrial electron transport chain and oxidative phosphorylation m

80 as an electron carrier in the mitochondrial electron transport chain and plays a key role in apoptos

81 produced at complex III of the mitochondrial electron transport chain and released into the intermemb

82 itochondria including the citric acid cycle, electron transport chain and ROS production and scavengi

83 ROS production is primarily mediated by the electron transport chain and the proton motive force con

84 alternative is that the lack of a functional electron transport chain and the resulting reduction in

85 Relatedly, SDH sits at the crossroad of the electron transport chain and tricarboxylic acid (TCA) cy

86 on ferredoxin reduced by the photosynthetic electron transport chain and, thus, on light, and the NA

87 harboring wild-type genomes have functional electron transport chains and propagate more vigorously

88 RNA, blocks the assembly of complex I in the electron transport chain, and causes an arrest in embryo

89 ired for the tricarboxylic acid (TCA) cycle, electron transport chain, and oxidative phosphorylation,

90 ation is given by phosphorylation subsystem, electron transport chain, and substrate dehydrogenation

91 O-A knockdown (KD) on ATP, oxidative stress, electron transport chain, and survival following exposur

92 oxidase, xanthine oxidase, the mitochondrial electron transport chain, and uncoupled endothelial nitr

93 Recently, complex II of the electron transport chain appears to be more important th

94 lycolysis, the tricarboxylic acid cycle, and electron transport chain, are coordinately induced at th

95 s of membrane potential or inhibition of the electron transport chain, as confirmed by addition of ca

96 SIRT3 rescued the IR-induced blockade of the electron transport chain at the level of complex III, at

97 hrome c (cyt c) is known for its role in the electron transport chain but transitions to a peroxidase

98 ation which reduced the effectiveness of the electron transport chain by lowering ATP and increasing

99 in both the tricarboxylic acid cycle and the electron transport chain, can lead to a variety of disor

100 bility of our method by assembling a minimal electron transport chain capable of adenosine triphospha

101 e found that inhibition of the mitochondrial electron transport chain causes paralysis as well as mus

102 that of control mice correlating with higher electron transport chain CcO activity in Ngb-H64Q-CCC-tr

103 e-S cluster biosynthesis, leading to reduced electron transport chain complex (ETC) activity and mito

104 e dehydrogenase A (SDHA), a key component of electron transport chain complex (ETC) II.

105 Moreover, electron transport chain complex (I, V) decrease in FECD

106 loss of mitochondrial respiration, decreased electron transport chain complex activity, and mitochond

107 trium and cervix function, and mitochondrial electron transport chain complex enzymatic activities we

108 s of riboflavin, downstream metabolites, and electron transport chain complex I activity.

109 Electron transport chain complex I and complex II activi

110 d skeletal muscle mitochondrial respiration, electron transport chain complex I dysfunction, as well

111 ardial stunning resulting from mitochondrial electron transport chain complex I dysfunction.

112 The acetylation status of electron transport chain Complex I protein NDUFB8 was si

113 ess is negatively regulated by mitochondrial electron transport chain complex I through both cell int

114 ration rate that is likely due to defects in electron transport chain complex I.

115 nduced reactive oxygen species generation at electron transport chain complex I.

116 ochondrial B-oxidation reduces mitochondrial electron transport chain complex II activity, contributi

117 nduces accumulation of misfolded subunits of electron transport chain complex II and complex V, resul

118 Mitochondrial cristae contain electron transport chain complexes and are distinct from

119 logy and altered expression of mitochondrial electron transport chain complexes and dynamics-regulati

120 Electron transport chain complexes are downregulated, po

121 The mitochondrial electron transport chain complexes are organized into su

122 Mitochondrial electron transport chain complexes are organized into su

123 e process of dismantling their mitochondrial electron transport chain complexes as they adapt to anae

124 respectively, with no significant change in electron transport chain complexes expression.

125 drial mass and differential contributions of electron transport chain complexes I and II to respirati

126 As a result, electron transport chain complexes show significant redu

127 ngly, although subunits of the mitochondrial electron transport chain complexes were reduced at the p

128 Furthermore, assembled, electron transport chain complexes were significantly mo

129 function, as it reflects the activity of the electron transport chain complexes working together.

130 dative phosphorylation (citrate synthase and electron transport chain complexes) markers and COX IV (

131 sphorylation, dysfunctional mitochondria and electron transport chain complexes, and depleted ATP sto

132 complex (TRiC) chaperonin, the mitochondrial electron transport chain complexes, and the circadian cl

133 he enzymatic activities of the mitochondrial electron transport chain complexes.

134 tochondrial oxygen consumption by inhibiting electron transport chain complexes.

135 spite no change in protein or mRNA levels of electron transport chain complexes.

136 lators of the respiratome; the mitochondrial electron transport chain (complexes I-IV) and the FoF1-A

137 re we show a role for the dysfunction of the electron transport chain component cytochrome c oxidase

138 ing ATP5A (ATP synthase F1 subunit alpha)-an electron transport chain component.

139 ndicated that Pitx2 activated genes encoding electron transport chain components and reactive oxygen

140 ive capacity and abundant expression of both electron transport chain components and uncoupling prote

141 Chlorate-specific transcription of electron transport chain components or the CRI was not o

142 nt TCP/TRiC/CCT chaperonin and mitochondrial electron transport chain components.

143 n center and its proper function requires an electron transport chain composed of NADH (or NADPH), cy

144 been linked to flavin photoreduction via an electron transport chain comprising three evolutionarily

145 The mitochondrial electron transport chain consists of individual protein

146 Our results suggest that the mitochondrial electron transport chain contributes to evofosfamide act

147 ium of cultured human cells with a defective electron transport chain decreased the extracellular lac

148 Our results show that mitochondrial electron transport chain defect initiates a retrograde s

149 s of AIF in fibroblasts led to mitochondrial electron transport chain defects and loss of proliferati

150 id metabolism, as well as the first complete electron transport chain described for a member of the C

151 ich are involved in energy generation by the electron transport chain, detoxification of host immune

152 show that electrons enter the photosynthetic electron transport chain during EEU in the phototrophic

153 aging theories and implicates mitochondrial electron transport chain dysfunction with subsequent inc

154 Campylobacter jejuni harbors a branched electron transport chain, enabling respiration with diff

155 I represses genes critical for mitochondrial electron transport chain enzyme activity, oxidative stre

156 Electron transport chain (ETC) activity generates an ele

157 A decline in electron transport chain (ETC) activity is associated wi

158 ytosolic H(2)O(2) but leads to mitochondrial electron transport chain (ETC) activity.

159 l mass, membrane potential, respiration, and electron transport chain (ETC) activity.

160 cations of Krebs cycle components as well as electron transport chain (ETC) alterations.

161 is an electron carrier in the mitochondrial electron transport chain (ETC) and antioxidant.

162 al genes, thus enhancing the capacity of the electron transport chain (ETC) and restoring mitochondri

163 which phenazines abstract electrons from the electron transport chain (ETC) and thereby generate reac

164 ae morphology, fusion in TM cells configures electron transport chain (ETC) complex associations favo

165 Consistent with this, low electron transport chain (ETC) Complex I and Complex II

166 ns with the mRNAs encoding the mitochondrial electron transport chain (ETC) complex I as well as hund

167 as well as significantly decreased (40%-50%) electron transport chain (ETC) complex I, II, IV, V, and

168 Assays of mitochondrial electron transport chain (ETC) complex I, IV, V activiti

169 myoblast cell lines display a severe loss of electron transport chain (ETC) complexes and exhibit com

170 thesis by interacting with components of the electron transport chain (ETC) complexes III, IV, and V,

171 We genetically disrupted electron transport chain (ETC) complexes in the intestin

172 abundance of mitochondria and high levels of electron transport chain (ETC) complexes within these mi

173 ads to suppression and loss of mitochondrial electron transport chain (ETC) complexes.

174 ultiomic analysis revealed downregulation of electron transport chain (ETC) components in chRCC that

175 ed increases in mitochondrial mRNAs encoding electron transport chain (ETC) components.

176 lear encoded components of the mitochondrial electron transport chain (ETC) coordinated with an incre

177 Electron transport chain (ETC) defects occurring from mi

178 e the relative contribution of mitochondrial electron transport chain (ETC) derived H(2)O(2) versus c

179 Mitochondrial electron transport chain (ETC) disorders cause severe ne

180 The mitochondrial electron transport chain (ETC) enables many metabolic pr

181 ion changes, whereas biochemical analysis of electron transport chain (ETC) enzyme activities showed

182 MISTR proteins are associated with electron transport chain (ETC) factors and activated by

183 glycolysis and to transfer electrons to the electron transport chain (ETC) for fueling thermogenesis

184 that cancer cells become independent of the electron transport chain (ETC) for survival.

185 aenorhabditis elegans, reduced mitochondrial electron transport chain (ETC) function during developme

186 High glucose levels or mutations affecting electron transport chain (ETC) function inhibited amino

187 The electron transport chain (ETC) functions at an elevated

188 le and negatively regulates transcription of electron transport chain (ETC) genes.

189 ng the following: mRNA and protein levels of electron transport chain (ETC) genes; mitochondrial dyna

190 The Mycobacterium tuberculosis (Mtb) electron transport chain (ETC) has received significant

191 or lifespan extension from inhibition of the electron transport chain (ETC) in Caenorhabditis elegans

192 kinases bound complex I of the mitochondrial electron transport chain (ETC) in spermatogenic and in c

193 s, we find that impaired NADH oxidation upon electron transport chain (ETC) inhibition depletes aspar

194 The mitochondrial electron transport chain (ETC) is necessary for tumour g

195 hondria undergo fragmentation in response to electron transport chain (ETC) poisons and mitochondrial

196 s a positive regulator of key genes encoding Electron Transport Chain (ETC) proteins and stimulates o

197 ction through the coupled integration of the electron transport chain (ETC) with oxidative phosphoryl

198 by hypoxia or by chemical inhibition of the electron transport chain (ETC), both of which are known

199 evealed that among components of the aerobic electron transport chain (ETC), only genes involved in t

200 rotein, acting as an electron carrier in the electron transport chain (ETC), where it shuttles electr

201 CoQ10 is an essential component of the electron transport chain (ETC), where it shuttles electr

202 t c) plays a vital role in the mitochondrial electron transport chain (ETC).

203 of respiratory quiescence by remodeling the electron transport chain (ETC).

204 ts actions on complex I of the mitochondrial electron transport chain (ETC).

205 EKO)), which induces loss of function of the electron transport chain (ETC).

206 proteins in complexes I, III, and IV of the electron transport chain (ETC).

207 es in the tricarboxylic acid (TCA) cycle and electron transport chain (ETC).

208 g bioenergetics and enzyme activities of the electron transport chain (ETC).

209 ase in mitochondrial encoded subunits of the electron transport chain (ETC).

210 f the heme and iron-sulfur cluster-dependent electron transport chain (ETC).

211 (TCA) cycle, and ATP synthesis powered by an electron transport chain (ETC); instead, they produce AT

212 ochrome c oxidase (COX) in the mitochondrial electron transport chain (ETC); suppression of COX activ

213 (II)Phthalocyanines were linked to different electron-transport chains featuring pairs of electron ac

214 tem that allows precise perturbations of the electron transport chain for the understanding of the ca

215 me is essential for processing heme into the electron transport chain for use as an electron acceptor

216 nted here suggest that the first part of the electron transport chain from formate to fumarate or Cl-

217 d from electron pairs being passed along the electron transport chain from NADH to O(2) generates a m

218 anding of the structural organization of the electron transport chain from the original idea of a com

219 radient to generate ATP and interfering with electron transport chain function can lead to the delete

220 types, while copy number alterations in the electron transport chain gene SCO2, fatty acid uptake (C

221 ytes; however, no changes in nuclear-encoded electron transport chain gene transcripts or mtDNA copy

222 n is detrimental, partial suppression of the electron transport chain has been shown to extend C. ele

223 ochrome-c-oxidase, COX) of the mitochondrial electron transport chain have been implicated in the pat

224 sm to maintain a certain redox status of the electron transport chain, hence allowing proper photosyn

225 PINK1, as well as chemical inhibition of the electron transport chain, impaired lysosomal activity an

226 ranslation of most protein components of the electron transport chain in lymphoma cells, and many of

227 f the two photosystems of the photosynthetic electron transport chain in the chloroplasts of plants a

228 tion, we explored whether restoration of the electron transport chain in this organism also affected

229 of their life cycle involves an alternative electron transport chain in which rhodoquinone (RQ) is r

230 Therefore, the lack of functional electron transport chains in SCV S. aureus and wild-type

231 assays narrowly targeting components of the electron transport chains in their native environments.

232 The mitochondrial electron transport chain includes an alternative oxidase

233 rdiolipin content, preserved activity of the electron transport chain including mitochondrial complex

234 Redox cycling, mitochondrial DNA damage and electron transport chain inhibition have been identified

235 Electron transport chain inhibition is the main pathway

236 Finally, potassium cyanide, an electron transport chain inhibitor, briefly stops growth

237 the actual rates observed in the absence of electron transport chain inhibitors, so maximum capaciti

238 of mtDNA-encoded genes is impaired, and the electron transport chain is compromised, fueling into a

239 erefore, it is likely that relaxation in the electron transport chain is not responsible for the asym

240 also known as complex V of the mitochondrial electron transport chain, is the main cellular energy-ge

241 ons were observed in proteins throughout the electron transport chain membrane complexes, ATP synthas

242 es, respiration occurs via the mitochondrial electron transport chain (mETC) composed of several larg

243 in model organisms has revealed roles in the electron transport chain, mitochondrial protein homeosta

244 e methods severely disrupt the mitochondrial electron transport chain, mtDNA-depleted cells still mai

245 model of the reactions in the photosynthetic electron transport chain of C3 species.

246 serves as the last enzyme in the respiratory electron transport chain of eukaryotic mitochondria.

247 dase, the terminal enzyme in the respiratory electron transport chain of mitochondria, from hippocamp

248 Disruption of the electron transport chain of S. aureus genetically (hemB

249 to perturbations in mitochondrial mass, the electron transport chain, or emission of reactive oxygen

250 ncoding enzymes of tricarboxylic acid cycle, electron transport chain, oxidative phosphorylation, ele

251 RT5-treated membrane proteins pointed to the electron transport chain, particularly Complex I, as bei

252 y challenged to co-ordinate the abundance of electron transport chain protein subunits expressed from

253 The organization of the mitochondrial electron transport chain proteins into supercomplexes (S

254 However, expression levels of the electron transport chain proteins NDUFB8 (complex I), AT

255 ndrial architecture, increased expression of electron transport chain proteins, and depletion of fat

256 man AML, treatment with ddC decreased mtDNA, electron transport chain proteins, and induced tumor reg

257 igh-confidence approach, we demonstrate that electron transport chain proteins, especially the matrix

258 16 of 27 identified proteins), in particular electron transport chain proteins.

259 lso known as complex II of the mitochondrial electron transport chain, providing support for the bifu

260 d either endogenously, through mitochondrial electron transport chain reactions and nicotinamide aden

261 n such as DOX influence on the mitochondrial electron transport chain, redox cycling, oxidative stres

262 ion. Inhibition of Complexes I and IV of the electron transport chain reduced neurite outgrowth in ZI

263 but were replicated using inhibitors of the electron transport chain respiratory complexes I, III, a

264 T cells by interfering with the formation of electron transport chain respiratory supercomplexes.

265 can cause hyper-reduction of the chloroplast electron transport chain, resulting in oxidative damage.

266 , which also hosts the final cofactor in the electron transport chain, riboflavin.

267 l changes, including decreased expression of electron transport chain subunit genes and impaired ener

268 Two atypical mitochondrial electron transport chain subunits (Ndufa4l2 and Cox4i2)

269 and biogenesis by boosting the expression of electron transport chain subunits and of factors essenti

270 ptake induced direct O-GlcNAcylation of many electron transport chain subunits and other mitochondria

271 way, ion channels and atypical mitochondrial electron transport chain subunits.

272 ctors, mitochondrial ribosomal proteins, and electron-transport chain subunits.

273 Other components of the electron transport chain such as the NADH dehydrogenases

274 (2) production, activity of mitoflashes, and electron transport chain supercomplex formation.

275 groups including genes for the mitochondrial electron transport chain, tetrapyrrole biosynthesis, car

276 Q (Q (n) ) is a vital lipid component of the electron transport chain that functions in cellular ener

277 he carbonyl of acetate to the membrane-bound electron transport chain that generates ion gradients dr

278 ocean-associated Margulisbacteria encode an electron transport chain that may support aerobic growth

279 By contrast, we show that complex I of the electron transport chain, the malate-aspartate shuttle a

280 iological data suggest that Aer monitors the electron transport chain through the redox state of its

281 potential gradient that is generated by the electron transport chain to drive the synthesis of ATP(1

282 In order for the electron transport chain to function, electron shuttling

283 electron transfer to route their respiratory electron transport chain to insoluble electron acceptors

284 l structure and function, repurposing of the electron transport chain to superoxide production, and N

285 ld and included nearly all components of the electron transport chain, tricarboxylic acid cycle, and

286 Inhibition of complex I of the mitochondrial electron transport chain using phenformin activated AMPK

287 We assembled the entire electron transport chain using the purified soluble doma

288 that can be transferred to the mitochondrial electron transport chain via the electron transfer flavo

289 are critical components of the mitochondrial electron transport chain, we hypothesized that reduced r

290 produced by complex III of the mitochondrial electron-transport chain were required for macrophage ac

291 wastage ('overpotential requirement') across electron-transport chains where rate and power must be m

292 P metabolism, glutathione metabolism and the electron transport chain, which belong to the induced ef

293 ression of vital components of mitochondrial electron transport chain, which compromise bioenergetics

294 on ferredoxin reduced by the photosynthetic electron transport chain, which fuels reducing power to

295 ation, electrons leak from the mitochondrial electron transport chain, which is captured by molecular

296 t also maintain the iron-rich photosynthetic electron transport chain, which most likely evolved in t

297 r genes, all components of the mitochondrial electron transport chain, which show significant loss of

298 nction with an uncoupler or interrupting the electron transport chain with cyanide (CN(-)) alters ER

299 t on the amount of ATP generated through the electron transport chain, with excess ATP going toward t

300 pecies (ROS) generated as by-products of the electron transport chain within mitochondria significant