ライフサイエンスコーパス: electron-dense

1 ans, the typical presynaptic terminal has an electron-dense active zone surrounded by synaptic vesicl

2 i along the apical surface and intercellular electron-dense adhesive junctions that resemble adherens

3 d the accumulation of large, well-demarcated electron-dense aggregates but no characteristic membrane

4 is present in subendothelium in the form of electron-dense aggregates having diameters varying betwe

5 e: Most notably, the presence of cytoplasmic electron-dense aggregates in podocytes.

6 irions that contain "eccentric condensates," electron-dense aggregates located outside seemingly empt

7 d Lon-knockdown cells is the accumulation of electron-dense aggregates within mitochondria.

8 duced reserpine-sensitive dissipation of the electron-dense aggregates, compatible with the idea that

9 th some particles containing multiple small, electron-dense aggregates.

10 omplex invagination resulting in membranous, electron-dense aggregates.

11 ectron microscopical studies showed that the electron-dense aggregrates in gastrin cell secretory gra

12 ; however, the cores typically appeared less electron dense and more rod shaped than WT virions.

13 site of their interaction, that can be made electron dense and reimaged at high resolution in the el

14 1(+)MHC-II(+) compartments are predominantly electron dense and, in these cells, empty MHC-II molecul

15 3DBs are unusual electron-dense and dynamic structures driven by the acce

16 bacteria in membrane-bound vacuoles and both electron-dense and electron-lucent forms.

17 um containing linear lamellae of alternating electron-dense and electron-lucent material, reflecting

18 on, the rER- and plasma-membrane pockets are electron dense, and sesquiterpenes are detectable only i

19 Arp2/3 form apical actin-rich microvilli and electron-dense apical junctions.

20 es and subsequently becomes localized in the electron-dense area of the apical complex.

21 ochondria from Shh-treated neurons were more electron-dense, as revealed by electron microscopy, and

22 on the sulfonamide nitrogen that contain an electron dense atom, such as a fluorine, are favored in

23 nvasion by participating in the formation of electron-dense band at the base of the parasite infectio

24 There is an electron-dense band to separate the parasite from host c

25 escent-shaped patch that fully resembles the electron-dense band.

26 partial loss of microvilli, and retention of electron-dense biliary material.

27 cells in pn demonstrated an accumulation of electron dense bodies.

28 nce measurements further revealed that these electron-dense bodies are rich in phosphorus and calcium

29 on of CryAB(R120G) leads to the formation of electron-dense bodies characteristic of the DRMs and ide

30 ticles are visible by electron microscopy as electron-dense bodies in the cytoplasm.

31 propose that these distinctive Ro-associated electron-dense bodies may represent structure(s) importa

32 The presence of immunogold-labeled electron-dense bodies was correlated with the presence o

33 Instead, novel round, electron-dense bodies were found associated with the vir

34 e observed a range of structures, from small electron-dense bodies within larger compartments to dens

35 there was an accumulation of membrane-coated electron-dense bodies, crescents, and immature virus par

36 reviously unreported nuclear and cytoplasmic electron-dense bodies.

37 ze predominantly to the cell poles and to an electron-dense body in the cytoplasm.

38 croscopy revealed characteristic deposits of electron-dense bundles of hollow microtubules with a 40

39 Similar to the vertebrate organization, electron-dense cell networks penetrated from the outer l

40 The vertebrate distinction between electron-dense cells in the most external connective tis

41 uclear volume and an increase in the size of electron-dense chromatin bodies; neither of these morpho

42 Assembly into an electron-dense coat then helps in budding off membrane t

43 composed of small ring-shaped profiles with electron-dense coats.

44 most similar to wild-type (WT) virions with electron-dense, conical cores.

45 enging because of difficulties in delivering electron-dense contrast agents to specific subcellular t

46 nsisting of multiple protofilaments, with an electron dense core located in the center of the filamen

47 approximately 7 nm external diameter and an electron dense core, and to form channels of 50picoSieme

48 a polar terminal organelle having a central electron-dense core and adhesin-related proteins cluster

49 inchworm-like conformational changes of its electron-dense core are leveraged against a cytoplasmic

50 rizing the physicochemical properties of the electron-dense core atrial gland vesicles from Aplysia c

51 ludes determination of the dimensions of the electron-dense core by transmission electron microscopy

52 ive novel carbon dots that all consist of an electron-dense core covered by an amine rich ligand shel

53 rupted CA-SP processing, cDNA synthesis, and electron-dense core formation.

54 ytadherence, and, in some cells, an atypical electron-dense core in the attachment organelle.

55 his effect was associated with a loss of the electron-dense core of G cell secretory vesicles.

56 t that HMW2 is the defining component of the electron-dense core of the terminal organelle.

57 complex membrane-bound cell extension is an electron-dense core of two segmented rods oriented longi

58 plasma cell is defined by the presence of an electron-dense core that appears as paired, parallel bar

59 dase E, chromogranin C, and IL-2, and had an electron-dense core typical of secretory vesicles.

60 l questions regarding the composition of the electron-dense core, the means by which the terminal org

61 a single perimetral membrane surrounding an electron-dense core.

62 ane-bound cell extension distinguished by an electron-dense core.

63 e mycoplasma cell possesses a characteristic electron-dense core.

64 ll extension containing an intracytoplasmic, electron-dense core.

65 ental cycle, transitioning between a smaller electron dense-cored cell (DC), which has a dense nucleo

66 s into sub-compartments sometimes visible as electron dense cores.

67 The electron-dense cores of regulated secretory granules in

68 leavage of the SP-NC junction, production of electron-dense cores, and cDNA synthesis but blocked ret

69 ers of these particles that accumulate small electron-dense cores.

70 Moreover, we localized TRIM46 to the electron dense cross-bridges and show that depletion of

71 bundles of closely spaced microtubules with electron dense cross-bridges, referred to as microtubule

72 e outer integument of the seed coat lost the electron-dense cuticle layer at its surface and displaye

73 dense line of myelin sheaths to accommodate electron dense cytoplasm derived from the oligodendrogli

74 ircular or oval in outline, while those with electron-dense cytoplasm (dark cells) had an irregular o

75 e most common of which is an accumulation of electron-dense cytoplasm within some sheaths, a change w

76 the Src-related kinases are associated with electron-dense cytoplasmic domains and plasma membrane d

77 form within specific PAS-diastase-resistant electron-dense cytoplasmic granules.

78 Large electron-dense cytoplasmic inclusions and clusters of sc

79 protein determinants, which are assembled in electron-dense cytoplasmic structures known as germ or p

80 CT were undergoing electron dense degeneration but still sometimes formed a

81 with mesangial hypercellularity (30 vs. 5%), electron dense deposits (62 vs. 20%), and endothelial tu

82 unofluorescence microscopy and subepithelial electron dense deposits along the glomerular basement me

83 ules evolved from electron lucent with small electron dense deposits at E15 to more electron dense gr

84 ays an irregular morphology and round, dark, electron dense deposits that do not give rise to a diffr

85 h full house immunofluorescence and multiple electron dense deposits.

86 ly in regions corresponding to subepithelial electron dense deposits.

87 inflammatory renal disease characterized by electron-dense deposits and complement C3 on the glomeru

88 Electron microscopy revealed finely granular electron-dense deposits coating the surfaces of frayed d

89 es of renal lesions revealed the presence of electron-dense deposits in affected arteries, and IgG, I

90 from individuals with Alzheimer's disease as electron-dense deposits located exclusively in the cytop

91 opy showed extensive amorphous subepithelial electron-dense deposits with intervening spikes along th

92 he formation of mesangial and subendothelial electron-dense deposits.

93 ngial and subendothelial immune complex-type electron-dense deposits.

94 In addition, small electron-dense dot-like structures measuring approximate

95 e inhibitors caused a marked accumulation of electron-dense double-membrane-limited AVs, containing c

96 1-deficient mice were next perfused with the electron dense dye Ruthenium Red.

97 By contrast, electron-dense endosomes that could be confused with ALI

98 ganic molecules, as distinguishing these low-electron dense entities from their similar liquid-phase

99 unique 15-protofilament microtubules and an electron-dense extracellular matrix have been proposed t

100 QDs are both fluorescent and electron dense, facilitating their use for correlated mi

101 In addition to active site binding by Cm, an electron-dense feature resembling the enzyme's product i

102 Both electron-dense features demonstrated the presence of gad

103 An electron-dense filamentous material, detected within ext

104 n the deep cerebellar nuclei showed ~ 100 nm electron-dense foci in the basal lamina of the vasculatu

105 on of crescent membranes on the periphery of electron-dense globular masses but few mature particles.

106 iferation or necrosis by light microscopy or electron-dense glomerular basement membrane deposits by

107 ol with a relatively small (0.8 nm diameter) electron dense gold cluster compound, undecagold monoami

108 heart showed aberrant intrasarcoplasmic and electron-dense granular filamentous aggregates that were

109 , the association of crescent membranes with electron-dense granular material, is perturbed when expr

110 ing tubular elements were separated from the electron-dense granular viroplasm, which accumulated in

111 L protein is required for the association of electron-dense, granular, proteinaceous material with th

112 he finding that sporozoites have a different electron-dense-granule composition, we have now found th

113 small electron dense deposits at E15 to more electron dense granules with complex patterns of interna

114 Thus, CgA-expressing A35C cells showed electron-dense granules approximately 180-220 nm in diam

115 Furthermore, the presence of numerous electron-dense granules around the phagosomes indicated

116 imal kingdom is the presence of perinuclear, electron-dense granules called nuage.

117 Centriolar satellites are numerous electron-dense granules dispersed around the centrosome.

118 mmunoreactivity localized to the cytoplasmic electron-dense granules in ASPS.

119 roscopy analysis revealed a higher number of electron-dense granules in Ctr2(-/-) mast cells than in

120 O-gold-affinity method detected histamine in electron-dense granules of mast cells in control and inj

121 vacuole of plants (tonoplast) and the small electron-dense granules of some parasites (acidocalcisom

122 vealed neurons containing distinctive large, electron-dense granules, which could reliably be used to

123 metaphosphates are enriched in insoluble and electron-dense granules.

124 appeared ultrastructurally as intracellular electron-dense granules.

125 n developing macronuclei, Pdd1p localizes to electron-dense, heterochromatic structures that contain

126 ncreases .OH generation from radiolysis with electron-dense Hf(12) secondary building units (SBUs) to

127 Upon X-ray irradiation, electron-dense Hf(12) secondary building units serve as

128 In contrast, electron-dense, high-energy carbon species (C-N, C=C, C=

129 ed luminal and abluminal vesicles containing electron-dense horseradish peroxidase-reaction product w

130 argely intact in the mid-SC, but replaced by electron-dense (hydrophilic) clefts (lacunae) that expan

131 the presence of LDI-1 WW, VLPs were found in electron-dense inclusion bodies in the cytoplasm of tran

132 resulted in a rapid massive accumulation of electron-dense inclusion bodies in the RPE.

133 koid lumen, and differential accumulation of electron-dense inclusion bodies.

134 ation and assembly take place in cytoplasmic electron dense inclusions termed viroplasms (VPs).

135 rplastic mitochondria, some of which contain electron dense inclusions.

136 children have (1) swollen mitochondria with electron-dense inclusions and abnormal inner-membrane mo

137 elopmental epileptic encephalopathies showed electron-dense inclusions, lipid droplets, osmiophilic m

138 tory areas of the cytoplasm contained large, electron-dense inclusions, some of which had partially c

139 Both types of cell contained highly electron-dense inclusions, which probably represent phag

140 ns showed markedly thickened endothelium and electron-dense interstitial deposits.

141 arance, associated with collagen fibrils and electron-dense intracellular fragments of collagen fibri

142 Electron-dense intracellular precipitates and the outer

143 alent activation of C3 convertase and highly electron-dense intramembranous deposits.

144 Ultrastructural analysis revealed both electron-dense intranuclear deposits and cytoplasmic inc

145 odeling of drug-enzyme interactions, but the electron-dense iodine atom of the inhibitor has been una

146 energy-dispersive X-ray spectroscopy showed electron-dense iron-containing aggregates within the mag

147 These contrast with the electron-dense knob protrusions expressed at the surface

148 ESEM) based on intra-vesicular generation of electron-dense labeling in axonal boutons.

149 noparticles (AuNPs) have emerged as powerful electron-dense labels for cryo-ET, but multiplexing usin

150 casional short crescent-shaped membranes and electron-dense lacy structures.

151 Electron-dense lamellar inclusions were observed in kera

152 mediated contacts displayed a characteristic electron-dense layer between the ER and the PM.

153 lved in the composition or maintenance of an electron-dense layer between the outer cell wall and the

154 lls by electron microscopy revealed a thick, electron-dense layer surrounding the opaque cells that w

155 These aggregated capsids were immersed in an electron-dense layer that appeared to be tegument.

156 composed of a spiral structure coated by an electron-dense layer underlying the knob membrane.

157 lysis revealed that although sarcomeres with electron dense M- and Z-bands are present in muscle fibe

158 gold nanoparticles are typically used as an electron-dense marker for immunohistochemically labeled

159 This electron-dense marker uniformly decorated the cell membr

160 and in those hemorrhaged and given IL-6, the electron-dense marker, administered intravenously, could

161 e stained infected cells with fluorescent or electron-dense markers specific for organelles and exami

162 Here we developed genetically-encoded, electron-dense markers using miniSOG.

163 itional electron microscopy studies revealed electron dense material in the t-tubules within the musc

164 rosis, lipid accumulation, and deposition of electron dense material throughout the glomeruli.

165 be mechanically reinforced by an intervening electron-dense material (EDM).

166 that immature virus particles and masses of electron-dense material accumulated in the absence of an

167 dot2 mutants show excess electron-dense material accumulating near SPBs, which we

168 ifically in scolopale cells causes abnormal, electron-dense material accumulation in the scolopale sp

169 Electron-dense material and midbodies are both absent fr

170 opy shows that plus-end foci are coated with electron-dense material and resemble similar foci in mon

171 ed that the virus particles were coated with electron-dense material but not aggregated at neutralizi

172 tron microscopy revealed the accumulation of electron-dense material in the mesangial matrix and age-

173 the centrosomal area in association with the electron-dense material surrounding centrioles.

174 bing within chlamydial inclusions, and (iii) electron-dense material surrounding inclusions.

175 iary root with a pronounced cross-banding of electron-dense material that should be important for the

176 es are lined on the cytoplasmic side with an electron-dense material to which is attached a monolayer

177 characterized by the deposition of abnormal electron-dense material within the glomerular basement m

178 d irregularly branching, pleomorphic, highly electron-dense material, resembling the hyaline structur

179 endoplasmic reticulum, coated vesicles, and electron-dense material.

180 t of the central pair complex by accumulated electron-dense material.

181 agmoplast MTs overlapped and were bridged by electron-dense materials in Arabidopsis thaliana.

182 Protein aggregates appeared as clumps of electron-dense materials that stained heavily for ubiqui

183 ytoplasm, where they were embedded within an electron-dense matrix material.

184 ctron microscopy revealed bacteria within an electron-dense matrix, similar to pneumococcal biofilms

185 s of structural definitions and reduction in electron-dense matrix.

186 The filopodial tips contain a heavy electron-dense matter that appears to attract the synapt

187 al oil droplet is replaced with a complex of electron-dense megamitochondria surrounded by hundreds o

188 lonRI and GM1 causes their redistribution to electron-dense membrane patches independently of each ot

189 Most presynaptic termini contain electron-dense membrane structures, often referred to as

190 ral studies showed numerous larger-sized and electron-dense mitochondria in nGD cerebral cortical neu

191 d cytochrome c oxidase-negative staining and electron dense mitochondrial inclusions were observed.

192 observed under LM colocalises well with the electron dense nanoparticle observed in EM.

193 The presence of electron-dense nanoparticles in vascular pericytes in th

194 r, transmission electron microscopy revealed electron-dense nanoparticles only in the neuroglia of no

195 confocal imaging of injected fluorescent and electron-dense nanoparticles, then relocalized by ATUM-S

196 e germ cells--the RNF17 granule, which is an electron-dense non-membrane bound spherical organelle wi

197 hat the punctate foci containing SREBP-2 are electron-dense nuclear bodies, similar or identical to s

198 It is visualized as an electron-dense object by transmission electron microscop

199 Labeled HA coincided with electron-dense, often noncircular membrane patches.

200 is a component of polar granules and nuage, electron-dense organelles characteristic of the germline

201 Transmission electron microscopy showed the electron-dense particle diameter to be 50-700 nm, sugges

202 ectron microscopy indicated that although no electron-dense particles at any stage of assembly were s

203 rthermore, Mx Hsp16.6 was detected in highly electron-dense particles in heat-shocked cells by immuno

204 ormation and cytoplasmic vacuoles containing electron-dense particles, whereas ALA+deferoxamine treat

205 oscopy, NADPH-d reaction product appeared as electron-dense particles.

206 lectron microscopy showed an accumulation of electron-dense patches of actin and strikingly altered m

207 oles, surrounded by a protein-rich matrix of electron-dense pericentriolar material (PCM) [4].

208 s visualized by LM correspond to homogeneous electron-dense perinuclear inclusion bodies (up to 1.4 m

209 When the drug is removed these proteins form electron-dense plaques which we term staples.

210 nstrated NaV1.6-positive staining within the electron dense podosome rosette structure.

211 4) The electron-dense pre- and postsynaptic apposition is expan

212 l organization, commonly containing a single electron-dense presynaptic density surrounded by a clust

213 These synapses are defined by electron-dense presynaptic structures called ribbons, co

214 obenzidine to convert the dye signal into an electron-dense product.

215 Electron-dense products were located almost exclusively

216 The electron-dense profiles of these contacts were easily id

217 The hallmark of most AZs is an electron-dense projection (DP) surrounded by SVs.

218 e center of active zones, we found elaborate electron-dense projections physically connecting vesicle

219 rder characterized by muscle dysfunction and electron-dense protein accumulations (nemaline bodies) i

220 and cells exposed to m-Tyr contained large, electron-dense protein aggregates, indicating that m-Tyr

221 This created an electron-dense reaction product that could be visualized

222 ternalized FM1-43 was photoconverted into an electron-dense reaction product.

223 showed that TlpC localized to a cytoplasmic electron-dense region.

224 tron microscopy (CLEM), we observed that the electron dense regions correlated with the GFP signal of

225 served in the cytoplasm, as well as discrete electron dense regions.

226 beyond a particular concentration and offer electron-dense regions at the center of the vesicle.

227 Moreover, the electron-dense regions containing these two enzymes were

228 are the appropriate size to account for the electron-dense regions in amyloid protofilaments.

229 M in infected cells and (ii) the presence of electron-dense regions in the INM, representing nucleoca

230 Particle buds and electron-dense regions of plasma membrane were observed

231 um and tonoplast in these cells, and also in electron-dense regions that are, as yet, unidentified.

232 The BETL cell nuclei showed reduced electron-dense regions, indicating sparse heterochromati

233 a region at the cell poles that is devoid of electron-dense ribosomes.

234 l-Vasicine is a quinazoline alkaloid with an electron dense ring and additional functionalities in it

235 by increasing the spacing between the inner electron-dense ring and the VLP membrane.

236 uter mitochondrial membranes are packed with electron-dense RNA fibrils and their volumes are closely

237 act allergy display progressive secretion of electron-dense secretory granule contents and retention

238 ed hydrogen atoms were transferred to nearby electron-dense selenide sites for H(2) formation and rel

239 We also describe a population of small electron-dense SGL cells, which we call type D cells and

240 ot processes formed a continuous, mesh-like, electron-dense sheet that incorporated the slit diaphrag

241 ical core shell and instead contained a thin electron-dense shell about 10 nm underneath the virion m

242 erical, acentric core and a crescent-shaped, electron-dense shell lying just inside the viral membran

243 gradient ultracentrifugation were spherical, electron dense, small (< 100 nm in diameter) particles,

244 ted with AcMNPV p10 fibrillar structures and electron-dense spacers that are precursors of the polyhe

245 ntly associated with mitochondria and a less electron-dense sphere of similar size that appears to be

246 ic structures in D. melanogaster, are evenly electron-dense spheres 1.5 microm in diameter (herein te

247 defined core structures, there were numerous electron-dense, spherical particles.

248 probably corresponds to the vacuole, and an electron dense spheroidal body, 300-500 nm in diameter,

249 and had an envelope studded with crown-like, electron-dense spikes.

250 is separated from the host cell by a unique electron-dense structure of unknown composition.

251 The nuage is a hazy electron-dense structure unique to germ cells and is enr

252 ae, Rubisco is localized to the pyrenoid, an electron-dense structure within the chloroplast.

253 in elongated entities resembling the striped electron dense structures upon TRIM37 depletion.

254 These electron-dense structures are conserved across species,

255 ned large mitochondria with lamellar-shaped, electron-dense structures at the ultrastructural level.

256 n force, shorter thin filaments, presence of electron-dense structures in myofibers, and thickening o

257 h internal eliminated sequences in transient electron-dense structures in the developing macronucleus

258 Inclusions appear as distinct granular electron-dense structures in the nucleus by immunoelectr

259 on microscopy revealed LANDs to be globular, electron-dense structures morphologically distinct from

260 Ultrastructurally, PS bodies corresponded to electron-dense structures of 150-300 nm diameter and res

261 sediment by electron microscopy, we observed electron-dense structures resembling chlamydial organism

262 cing led to the striking appearance of novel electron-dense structures that we named "exocyst rods,"

263 reveals that Cenpas are centriole-related or electron-dense structures with stripes.

264 cted by a variety of links and also carry an electron-dense surface coat.

265 ic protein Bruchpilot, calcium channels, and electron-dense T bars are concentrated at a fraction of

266 les were near the plasma membrane, sometimes electron-dense "tethers" appeared between the vesicle an

267 chondria with swollen matrices that are less electron-dense than matrices in normal mitochondria.

268 cells caused the walls of variants to become electron-dense, thin, and sinuous.

269 acellular matrix of the bmp mutant contained electron-dense, thread-like structures that were also pr

270 mony (TBSb), a compound that is sufficiently electron dense to have been observed to occupy the cavit

271 GBM permeability to the electron-dense tracer ferritin was dramatically elevated

272 stinal microvasculature, mice were given the electron-dense tracer horseradish peroxidase (HRP) after

273 robe analysis to monitor permeability to the electron-dense tracer lanthanum.

274 derivatives, which catalyze production of an electron-dense tracer, to genetically identify neurons,

275 PLT production and is distributed to a novel electron-dense tubular system-related compartment we hav

276 lved ribosomal dissociation and a late-onset electron-dense type displaying nuclear pyknosis and seve

277 detected only in vacuoles distinct from the electron-dense vacuoles and other organelles.

278 nt 3- or 2-fold increase in potassium in the electron-dense vacuoles and the iron-rich vacuoles, resp

279 re of the vacuoles and demonstrated that the electron-dense vacuoles correspond to what were describe

280 pyroantimoniate-osmium technique and as the electron-dense vacuoles observed in whole unfixed parasi

281 These results indicate that the electron-dense vacuoles of C. reinhardtii are very simil

282 X-ray microanalysis of the electron-dense vacuoles or polyphosphate bodies of C. re

283 that the heaviest (pellet) fraction contains electron-dense vacuoles rich in phosphorus, calcium, and

284 Purification of the electron-dense vacuoles using iodixanol density gradient

285 and X-ray microanalysis as acidocalcisomes (electron-dense vacuoles).

286 In isolated electron-dense vacuoles, PP(i)-driven proton translocati

287 ss of PfPM2, and an abundant accumulation of electron-dense vesicles in the digestive vacuole was obs

288 fusion complexes, which are characterized by electron-dense vesicles paired on either side of the fus

289 fusion, possibly by mediating fusion of the electron-dense vesicles to the plasma membrane.

290 reased insoluble TDP-43, as well as enlarged electron-dense vesicles, lipofuscin accumulation, finger

291 P signal can be visualized as photoconverted electron-dense vesicles.

292 granules, but there was an abundance of non-electron-dense vesicles.

293 t were ciliated and contained numerous large electron-dense vesicles.

294 II IN mutations, block the formation of the electron-dense viral core and inhibit reverse transcript

295 inducer showed virus factories with abnormal electron-dense viroplasms and intermediate density regio

296 In the absence of A14, electron-dense virosomes and distinct clusters of small

297 i), crescents appear at the periphery of the electron-dense virosomes, with the accumulated vesicles

298 ctron microscopy revealed cell "ghosts" with electron-dense walls.

299 plasma membrane and the production of small electron-dense whorls.