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1 n we analysed the association of genetically elevated levels of 36 blood cell traits (platelets, matu
5 hat reduced SIRT1 levels are associated with elevated levels of acetyl-HIF-1alpha, HIF-1alpha, and ar
6 ted signaling activation was associated with elevated levels of acetyltransferase P300/CBP-associated
8 mber of aggressive cancer cell lines display elevated levels of activated Rac1, a small GTPase widely
9 2 and ARPC3, actin polymerizing factors, and elevated levels of active cofilin, which mediates actin
13 overexpressed in many cancers, resulting in elevated levels of ADO that correspond to poor patient p
16 (HSAN) types IA and IC (IA/C) are caused by elevated levels of an atypical class of lipid named 1-de
17 f fatty acid amide hydrolase (FAAH) produces elevated levels of anandamide (AEA) and promotes fear ex
19 ients with a limited response to therapy had elevated levels of androgen receptor variant 7 (ARV7) an
21 of circulating angiotensin peptides revealed elevated levels of angiotensin II, III, IV, and 1-5 in D
23 free of interference from non-HCV pathogens, elevated levels of anti-viral and anti-bacterial drugs,
24 found that mice lacking caspase-2 displayed elevated levels of anxiety, impairment in reversal water
25 insulin deficiency rather than hyperglycemia elevated levels of apolipoprotein C3 (APOC3), an apolipo
27 acetylation of HIF-1alpha contributes to the elevated levels of aromatase in breast tissues of obese
33 pecific CSF profile, mainly characterized by elevated levels of B-cell related cytokines, distinguish
34 monstrates that T cell subsets with T21 show elevated levels of basal IFN signaling and hypersensitiv
35 ctions of Abeta in AD.SIGNIFICANCE STATEMENT Elevated levels of beta-amyloid (Abeta) in the brain are
40 that were genetically manipulated to produce elevated levels of BpuR exhibited altered levels of seve
41 n, we investigate the effect of diet-induced elevated levels of brain Hcy on the phenotype of a relev
43 enotypes of GGDEF mutants, instead having an elevated level of c-di-GMP, suggesting that the role of
45 radiation exposure with type-2 diabetes and elevated levels of C-reactive protein, a marker of chron
48 om LysM-Cre:BVR (fl/fl) showed significantly elevated levels of C5aR1 as well as chemokines (RANTES,
50 nded pediatric and adult KD cohorts revealed elevated levels of calprotectin in pediatric patients wi
52 motif in its promoter, which results in the elevated levels of carotenoids in SlBBX20 overexpression
53 r culture conversion displayed significantly elevated levels of CCL1, CCL3, CXCL1 and CXCL9 at the ti
54 or cavitary disease displayed significantly elevated levels of CCL1, CCL3, CXCL1, CXCL10 and CXCL11
56 ceptor activity is important for maintaining elevated levels of CD14 in biological fluids and a decre
57 e of tumor initiation vs normal development, elevated levels of CD271 can serve as a switch between p
58 observe synergistic tumour growth delays and elevated levels of CD4+ and CD8+ cells in tumours receiv
60 s show that municipal waste biogas contained elevated levels of chemicals associated with volatile ch
61 data demonstrate that PTB is associated with elevated levels of chemokines, which are partially rever
63 owed that patients with active pemphigus had elevated levels of circulating IL-17(+)(,) T(H)17, T(FH)
64 re hypersensitive to endotoxin and exhibited elevated levels of circulating Ly6C(+) monocytes and mac
67 esenchymal transition in the primary tumors, elevated levels of circulating tumor cells, and increase
70 of psychedelic phenomenology constitutes an elevated level of consciousness - as measured by neural
71 osystems worldwide face growing threats from elevated levels of contaminants from human activities.
76 vascular remodeling, and inflammation, with elevated levels of cytokines, including interleukin-1bet
77 d suppressive capacity in vivo, in line with elevated levels of cytotoxic T-lymphocyte-associated 4 (
79 at patients whose pancreatic cancers express elevated levels of Death Receptor 5 (DR5) and its downst
83 ved in brain slices and in vivo is caused by elevated levels of dopamine receptors (Drd1), which are
85 enitor cells; thus, loss of KLF4 resulted in elevated levels of dual-specificity tyrosine-(Y)-phospho
86 f SENP3 in breast cancer are associated with elevated levels of E2F targets, high tumor grade, and po
87 the Pirc rat model had demonstrated that the elevated level of each of these markers is correlated wi
89 omal cells produce over 90% of the ECM mass, elevated levels of ECM proteins derived from the tumor c
91 ult suggests that hydraulic damage caused by elevated levels of embolism is likely to be one of the k
92 by correcting lysosomal pH, are mediated by elevated levels of endogenous beta-cleaved carboxy-termi
94 ddition, children with ASD had significantly elevated levels of eotaxin-1, interferon-gamma, and IL-1
101 s, symptomatic AS patients had significantly elevated levels of FB (2.9- and 2.8-fold increase in pop
103 adherin, consistent with clinically reported elevated levels of FN and MMP9 in patient breast tumors
104 3 gene expression was markedly increased and elevated levels of Foxp3 + Treg cells were detected in c
108 eous-phase and surface chemistry resulted in elevated levels of gas-phase nitrogen dioxide (NO(2)).
110 alysis revealed that NME1(LOW) cells express elevated levels of genes associated with tumor aggressiv
111 ffered markedly from their Mexican source by elevated levels of genetic introgression from the high l
112 es of AxD are displayed by mice that express elevated levels of GFAP from a human WT GFAP transgene h
113 ulation of the HPA axis results in sustained elevated levels of glucocorticoids which impair neuronal
114 ose transporter 1 (GLUT1), which sustains an elevated level of glucose uptake required to maintain pr
116 memory and central memory CD4+ T-cells have elevated levels of glycolysis and oxidative phosphorylat
117 signalling and can be autoimmune (caused by elevated levels of GM-CSF autoantibodies) or hereditary
118 rmal breast reduction patients and contained elevated levels of growth factors, cytokines and protein
126 oalkyl substances (PFAS) chemical class, and elevated levels of HFPO-DA have been detected in surface
128 t prevalent cardiovascular disease (CVD) but elevated levels of high-sensitivity cardiac troponin T (
131 omised chromatin maturation, as indicated by elevated levels of histones H3K9 and H4K16 acetylation,
132 n analysis, individuals living in areas with elevated levels of household density had 1.24-fold incre
137 flammation resolved rapidly, as indicated by elevated levels of IL-10, arginase-1, and VEGF, and lowe
138 d disease severity, which is associated with elevated levels of IL-1beta and checkpoint kinase 1 phos
141 immunohistochemistry to detect significantly elevated levels of IL-35 and IL-37 (2 recently identifie
142 : This study shows, for the first time, that elevated levels of ILC2s is associated with infant RSV s
143 iffer in their histidine dietary intake, the elevated levels of imidazole propionate in type 2 diabet
144 rapy who are reported to exhibit chronically elevated levels of immune activity, had significantly hi
145 ls exposed to radiation shed TMPs containing elevated levels of immune-modulating proteins, one of wh
146 tly because the protective care that enables elevated levels of inbreeding can be reduced by inbreedi
148 erally dominated by taurine cattle, although elevated levels of indicine ancestry have been recorded
153 Lower SES is associated with significantly elevated levels of inflammatory markers of disease risk.
157 le bowel syndrome (IBS), are associated with elevated levels of intestinal histamine due to chronic i
158 ese workers are among the highest exposed to elevated levels of ionizing radiation, although their oc
162 acid 12-lipoxygenase (ALOX12) expression and elevated levels of its mitogenic metabolite, 12-(S)-hydr
164 ale (n = 13) Cbs(-/-) mice had significantly elevated levels of K212Hcy and K525Hcy modifications in
166 ependent cohorts that people with DS produce elevated levels of kynurenine and quinolinic acid, two t
167 diseases are similar: both are hypoxic, show elevated levels of lactate and other metabolic by-produc
168 sity lipoprotein) receptor gene (LDLR) cause elevated levels of LDL cholesterol and premature cardiov
171 hypercholesterolemia is characterized by an elevated level of low-density lipoprotein (LDL) choleste
172 rdiovascular disease is intimately linked to elevated levels of low-density lipoprotein (LDL) cholest
173 re cardiovascular disease caused by markedly elevated levels of low-density lipoprotein (LDL) cholest
174 al codominant genetic disorder, which causes elevated levels of low-density lipoprotein cholesterol (
175 g high endogenous Wnt signaling, we observed elevated levels of low-density lipoprotein receptor-rela
177 ypts isolated from CR-infected mice revealed elevated levels of LRP5/6 and FZD10 and beta-catenin co-
180 ely the size of a cell subpopulation with an elevated level of MDR transport in tumor samples, which
182 cken embryonic fibroblasts (CEFs) identified elevated levels of metabolites involved in glutamine cat
184 of large sub-adults can be attributed to the elevated levels of migratory and exploratory activities
185 S), we previously found adults with ADHD had elevated levels of mind wandering that contributed to im
187 zer near room temperature in the presence of elevated levels of moisture expected with the use of mem
188 conclude that hen harriers in Britain suffer elevated levels of mortality on grouse moors, which is m
189 18.0+/-5.9 versus 17.9+/-5.1 Nm/kg, P=0.04), elevated levels of MSTN-2 (myostatin-2), FBXO-32 (F-box
190 ing transient anemia, and was accompanied by elevated levels of muscle, liver and renal injury marker
191 equences from intragraft B cells also showed elevated levels of mutated rearrangements in the graft c
192 xpression led to high expansion activity and elevated levels of MutSbeta complex, indicating that Mut
196 Patients with nosocomial pneumonia exhibit elevated levels of neurotoxic amyloid and tau proteins i
197 o obvious behavioural effects were observed, elevated levels of neutral lipids and phospholipids rese
198 iral infections coinfected with bacteria had elevated levels of neutrophil activation markers but par
201 do not take significant averting action for elevated levels of nitrate, yet experience a higher prev
202 rom container plant nurseries often contains elevated levels of nitrogen (N) and phosphorus (P).
205 istant 5-InsP(7) analog into wild-type cells elevated levels of NUDT3 mRNA substrates and raised P-bo
208 constitutively high SOX6 expression promotes elevated levels of oxidative stress that create a therap
209 are largely pyrethroid-resistant, often with elevated levels of P450s that can metabolise and neutral
213 surmised that within tumors selecting for an elevated level of PD-1/PD-L1 interaction, there is a gre
215 ence of 2 immune endotypes: T2-like (with an elevated level of periostin in BALF) and non-T2/proinfla
216 s, offering opportunities to breed bees with elevated levels of pesticide tolerance in the future.
218 In these conditions, we show that there are elevated levels of PGE2 which activate sensory nerves, l
223 vation of the plasma contact system leads to elevated levels of plasma kallikrein, which cleaves high
224 Millions of people worldwide display mildly elevated levels of plasma lipids and cholesterol linked
225 roposed that in addition to these functions, elevated levels of polyamines promote longevity in vario
226 inflammatory bowel disease (IBD) and reduced elevated levels of pro-inflammatory mediators in tissue
230 , although the effect of chronic exposure to elevated levels of radiation on telomere maintenance is
234 s of ACOX1 protein and function resulting in elevated levels of reactive oxygen species in glia in fl
235 associated with increased cell division and elevated levels of reactive oxygen species in rapidly pr
236 ea As pldgamma1 mutant plants responded with elevated levels of reactive oxygen species to MAMP treat
238 cute inflammation, which is characterized by elevated levels of reactive oxygen species. Injection of
239 isolation-by-distance in African Americans, elevated levels of relatedness and homozygosity in Asian
242 cascades of several diseases associated with elevated levels of secreted phospholipase A(2) (sPLA(2))
245 ulation in which female ERalpha KO mice have elevated levels of serum estradiol (E2), testosterone, a
249 Sex chromosomes are predicted to harbour elevated levels of sexually antagonistic variation due t
250 nd restores coaggregation accordingly, while elevated levels of shaft pilins and SrtC2 produce long p
251 rimary fibroblasts from these mice exhibited elevated levels of Smad7, a negative regulator of the tr
253 lating EC-EVs from tumor-bearing mice harbor elevated levels of specific miRNAs (e.g. miR-30c, miR-12
257 er (PTSD) show heightened amygdala activity; elevated levels of stress hormones, including norepineph
261 ssociated with reduced CD4 T cell counts and elevated levels of T cell activation and viral load; it
262 ls in all ROIs, independent of age, and very elevated levels of tau were observed primarily in clinic
263 ation with ANTS, in turn, is associated with elevated levels of TH1, TH2, and proinflammatory cytokin
265 d MAIT cells in patients with STSS expressed elevated levels of the activation markers CD69, CD25, CD
267 ssue-repairing M2-like microglia, along with elevated levels of the anti-inflammatory cytokine, IL-10
268 ellular matrix components and also expressed elevated levels of the decidual prolactin Prl8a2, as wel
272 form of phosphofructokinase-2, resulting in elevated levels of the PFK-1 allosteric activator fructo
273 tured central nervous system cells exhibited elevated levels of the redox coenzyme nicotine adenine d
274 he biosynthetic domains are characterized by elevated levels of the RNA polymerase I subunit A (POLR1
276 nteractions of beta-amyloid peptides with an elevated level of their normal prion protein dendritic r
277 ies as a marker for beige adipocytes, showed elevated levels of thermogenic markers, including UCP1,
278 ypectomy blood samples demonstrated that the elevated levels of these four conserved markers persiste
281 vided the first genetic evidence implicating elevated levels of these three PRMTs in mammary gland tu
284 dle smaller compared to X. laevis [2], as do elevated levels of TPX2, a protein that enriches the cro
285 ion of the Abeta plaque environment revealed elevated levels of transcripts encoding proteins involve
287 ncy increases APOC3 and that this results in elevated levels of TRLs and accelerated atherosclerosis
288 vely with % HbA1c levels, while in controls, elevated levels of TSPAN8 were associated positively wit
289 generation (wet AMD) have been found to have elevated levels of Tumor Necrosis Factor-alpha (TNF-alph
291 that produce defective CD11b associate with elevated levels of type I interferon (IFN-I) in lupus, s
292 This immune activation is characterized by elevated levels of type I interferons (IFNs), which can
293 of type-A ARRs to autophagic vesicles, have elevated levels of type-A ARR proteins, and are hyposens
294 up-regulate ERAD complex components and have elevated levels of ubiquitinated proteins prior to manif
295 nation and that the loss of Bassoon leads to elevated levels of ubiquitinated synaptic proteins per s
298 sentation with an elevated respiratory rate; elevated levels of venous lactate, creatinine, or procal