ライフサイエンスコーパス: elevated plus maze

1 ty-related behavior (dark/light exploration, elevated plus maze).

2 y behavior, and anxiety (as expressed in the elevated plus-maze).

3 y-related tests (open field, light/dark box, elevated plus-maze).

4 and produced an anxiety-like response on the elevated plus maze.

5 was withdrawn and anxiety was measured in an elevated plus maze.

6 control animals in the open field arena and elevated plus maze.

7 LA and heightened anxiety, as measured on an elevated plus maze.

8 vioral correlates of anxiety measured in the elevated plus maze.

9 ntrols, but it did not alter behavior on the elevated plus maze.

10 Anxiety levels were also evaluated using an elevated plus maze.

11 ked wheel controls (LC) (20.7+/-5.7%) in the elevated plus maze.

12 creases levels of anxiety as measured by the elevated plus maze.

13 ced avoidance behavior of the animals in the elevated plus maze.

14 10 min prior to testing and examined in the elevated plus maze.

15 vehicle 30 or 60 min prior to testing in the elevated plus maze.

16 o reflected by an increase in anxiety in the elevated plus maze.

17 ther to explore or avoid the open arms of an elevated plus maze.

18 lso tested for anxiety-like behaviors on the elevated plus maze.

19 is, including the passive avoidance task and elevated plus maze.

20 was evaluated by the open field test and the elevated plus maze.

21 s mice moving in an open field box and in an elevated plus maze.

22 k box as well as open-arm exploration in the elevated plus maze.

23 r-exploratory (low-anxiety phenotype) in the elevated plus maze.

24 xiety-like behavior in restraint rats in the elevated plus maze.

25 havior in those animals as measured with the elevated plus maze.

26 an open field, while reducing anxiety in an elevated plus maze.

27 task, as previously reported but not in the elevated plus-maze.

28 al measures of anxiety-like responses in the elevated plus-maze.

29 proestrus female rats were examined with an elevated plus-maze.

30 hybridization 4 h after being tested on the elevated plus-maze.

31 anxiety-like behavior was accessed using an elevated plus-maze.

32 and was related to reduced fearfulness in an elevated plus-maze.

33 adigms, but contrast with those found in the elevated plus-maze.

34 encephalography, long-term potentiation, and elevated plus-maze.

35 id not display anxiety-like behaviors on the elevated-plus maze.

36 ease in anxiety-like behavior of rats on the elevated plus-maze 10 days after acute stress.

37 In this laboratory context, the widely used elevated plus maze (a measure of anxiety) induces a pers

38 uitary-adrenocortical (HPA) responses to the elevated plus maze, a behavioral stressor known to activ

39 using behavioral tests, i.e., light-dark and elevated-plus-maze activities.

40 so reduced entries into the open arms of the elevated plus maze after water restraint.

41 er from threats such as the open arms of the elevated plus maze and a predator.

42 exhibited elevated locomotor activity in the elevated plus maze and altered stress-coping strategies

43 izophrenia-relevant behaviors as measured by elevated plus maze and amphetamine-induced hyperlocomoti

44 e conclude that anxiety-like behavior in the Elevated Plus Maze and behavioral despair-like immobilit

45 Behavior in the elevated plus maze and behavioral suppression induced by

46 were subjected to behavioral stress using an elevated plus maze and blood was collected 15 min prior

47 Object recognition memory, anxiety on an elevated plus maze and body weight were unaffected by ph

48 ilient based on anxiety-like behavior in the elevated plus maze and context avoidance.

49 anxiogenic-like behavior as assessed by the elevated plus maze and defensive withdrawal tests.

50 aviors, reduced anxiety-like behavior in the elevated plus maze and deficits in the T-maze alteration

51 mice spent more time in the open arms of an elevated plus maze and exhibited spatial working memory

52 e underlying this phenotype, focusing on the Elevated Plus Maze and Forced Swim Test as relevant beha

53 vulnerabilities for altered behavior in the Elevated Plus Maze and Forced Swim Test, respectively.

54 ic- and antidepressant-like responses in the elevated plus maze and forced swim test.

55 layed increased anxiety-like behavior in the elevated plus maze and in a light/dark box.

56 vity, increased time in the open arms of the elevated plus maze and increased immobility during the t

57 wed decreases in open-arm exploration in the elevated plus maze and increased marble burying without

58 iors and reduced exploratory behavior in the elevated plus maze and light-dark box tasks.

59 l-related anxiety in rats as measured by the elevated plus maze and light/dark box exploration tests.

60 ssess genotype-dependent effects on anxiety (elevated plus maze and light/dark box), motor coordinati

61 (1A)-AR, and CAM alpha(1B)-AR animals in the elevated plus maze and light/dark box.

62 Anxiety-related behaviors in the elevated plus maze and locomotor responses to amphetamin

63 ent paradigm improved functional recovery on elevated plus maze and Morris water maze, concomitant wi

64 nd cognitive functioning were assessed using elevated plus maze and Morris water maze, respectively.

65 on also increases measures of anxiety in the elevated plus maze and neophobia to novel tastes.

66 -outs, specifically in the anxiety-provoking elevated plus maze and not in a familiar environment or

67 rs several days later in the light dark box, elevated plus maze and novelty-suppressed feeding test c

68 like behavior assessed using the open-field, elevated plus maze and novelty-suppressed feeding tests.

69 The effects of 4 weeks of wheel running on elevated plus maze and open field behavior were also inv

70 ecreased anxiety-like traits detected in the elevated plus maze and open field paradigms.

71 had increased anxiety-like behaviors in the elevated plus maze and open field tests but did not diff

72 ifferences in anxiety-like (measured via the elevated plus maze and open field tests) and depression-

73 produced an anxiolytic phenotype in both the elevated plus maze and open field tests, and increased t

74 reshold SDS and anxiety-like behavior in the elevated plus maze and open field while the activation o

75 ested for anxiety-related behavior using the elevated plus maze and open field, and for endocrine res

76 vHIP decreased anxiety-like behavior on the elevated plus maze and open field.

77 rdless of sex, increased anxiety on both the elevated plus maze and open field.

78 how heightened anxiety-like behaviors in the elevated plus maze and open-field tests.

79 reduced state of anxiety as assessed in the elevated plus maze and reduced Orexin mRNA compared to a

80 behavior including central area time in the elevated plus maze and thigmotaxis in the open field tes

81 y was also unchanged as measured in both the elevated plus maze and time spent immobile in a novel en

82 ited increased anxiety-like behaviour in the elevated plus maze and were more optimistic in the cogni

83 osed rats exhibited decreased anxiety in the elevated plus-maze and a trend for decreased TH-ir in th

84 ats showed less anxiety-like behavior in the elevated plus-maze and defensive withdrawal tests than L

85 e such as decrease in open-arm entries on an elevated plus-maze and increased susceptibility to penty

86 tabolite concentrations, and behavior in the elevated plus-maze and open field test.

87 yperlocomotion, an anxiogenic profile in the elevated plus-maze and open field tests, and reduced soc

88 rats exhibited increased locomotion in both elevated plus-maze and open field tests, suggesting heig

89 la (BLA), ERGR reduced anxiety, as tested on elevated plus-maze and open field, without affecting con

90 deficiency, we evaluated AC8 KO mice in the elevated plus-maze and open field.

91 xploratory anxiety-like behaviors, tested by elevated plus-maze and open-field tests.

92 implants increased indices of anxiety on the elevated plus-maze and produced a concomitant increase i

93 omy (OBX) altered defensive behaviors on the elevated plus-maze and the open-field differently in mal

94 educed anxiety-like behavior assessed in the elevated-plus maze and acoustic startle test, including

95 i.p.) produced anxiety-like behaviors in the elevated-plus maze and novel object exploration assays,

96 in both responders and non-responders in the elevated-plus maze and open field test.

97 d on the propensity to avoid open arms in an elevated-plus maze and sign-trackers (ST) that are prone

98 d sucrose rewards, as well as anxiety (i.e., elevated plus maze)- and stress (i.e., forced swimming)-

99 k avoidance responding in a shuttle box, the elevated plus maze, and an air puff-induced ultrasonic v

100 , decreased time spent in the open arm of an elevated plus maze, and an odor aversion associated with

101 lterations in gait, aberrant behavior in the elevated plus maze, and delayed decision-making.

102 or the anxiolytic effects of nicotine in the elevated plus maze, and elimination of alpha4beta2-nAChR

103 ce displayed an exacerbated phenotype in the elevated plus maze, and genes associated with vascular e

104 vity in various tests, including open field, elevated plus maze, and light/dark transition tests.

105 nce), anxiety-related responses (open field, elevated plus maze, and marble burying), and despair-lik

106 ng, decision-making in a T-maze, open field, elevated plus maze, and novel object exploration.

107 id hormone corticosterone in the open-field, elevated plus maze, and social interaction tests.

108 s of anxiety - the conditioned freezing, the elevated plus maze, and the defensive-withdrawal test.

109 ting rod method, followed by the open field, elevated plus maze, and Y-maze tests conducted during th

110 es of anxiety in the open field, light-dark, elevated plus-maze, and elevated zero maze tests.

111 essed during adulthood using the open-field, elevated plus-maze, and light/dark tests.

112 s when mice were assessed in the open-field, elevated-plus-maze, and forced swim tests.

113 When anxiety levels were assessed in the elevated plus maze, Apoe(-/-) mice showed more anxiety t

114 ke behaviors seen in the open field test and elevated plus maze, as well as decreased corticosterone

115 e behavior as measured by the open field and elevated plus maze assays does not seem to be affected b

116 Lesions had no effect on any measures in the elevated plus maze but attenuated operant suppression in

117 ike behavior in both groups, measured on the elevated plus maze, but did not affect mechanical hypers

118 ge of time dams spent in the open arms of an elevated plus-maze, but had no effect on the open-arm be

119 The increased open arm activity in the elevated plus-maze cannot therefore be secondary to incr

120 In the elevated plus maze, chronic MAP4343 tended to increase o

121 Affective (elevated plus-maze), cognitive (water-maze), and reprodu

122 ned by a decrease in open arm entries on the elevated plus maze compared to control rats and pseudopr

123 ime in and entries into the open arms of the elevated plus maze compared to handled controls, suggest

124 lar decreases in open arm exploration on the elevated plus maze compared to OVA male offspring expose

125 bles produces alterations in behavior on the elevated plus maze consistent with task-specific anxiety

126 rol-implanted rats either not exposed to the elevated plus maze (control) or 4 h post-behavioral stre

127 alone increased anxiety-like behavior on the elevated plus maze, CUS alone or in combination with MDM

128 Knockout adults were less anxious in the elevated plus-maze, defecated less, and head-dipped more

129 le, E2, P, or E2 + P: Effects on open field, elevated plus-maze, defensive freezing, and hot-plate ta

130 or fear-reducing effects as measured on the elevated plus-maze, despite stress-induced gut microbiot

131 Performance of mice in anxiety (open field, elevated plus maze, elevated zero maze, social interacti

132 iour was assessed at weekly intervals in the elevated plus-maze, elevated T-maze, and locomotor activ

133 e, and on behavior in two anxiety paradigms, elevated plus maze (EPM) and fear conditioning.

134 from these populations were subjected to the elevated plus maze (EPM) and novel environment to assess

135 ehaviors in adult and adolescent rats during elevated plus maze (EPM) exploration, including stretch

136 To address this, we subjected rats to the elevated plus maze (EPM) paradigm while simultaneously r

137 of two-trial light- dark (LD) and two-trial elevated plus maze (EPM) tests arranged in counterbalanc

138 In the elevated plus maze (EPM), AgNS-exposed rats showed great

139 loring standard and modified versions of the elevated plus maze (EPM), an innate anxiety paradigm.

140 in a battery of tests--novel field activity, elevated plus maze (EPM), and social interaction (SI) at

141 ssion and memory impairment were assessed by Elevated Plus Maze (EPM), Forced Swim Test (FST), Sucros

142 In the elevated plus maze (EPM), restraint decreased the number

143 hat systemic ML297 administration suppresses elevated plus maze (EPM)-induced neuronal activation in

144 hanges and increased open-arm entries in the elevated plus maze (EPM).

145 xiety-type behaviors were measured using the elevated plus maze (EPM).

146 bit reduced anxiety-related avoidance in the elevated plus maze (EPM).

147 l freezing, and an anxiety-like trait in the elevated plus maze (EPM).

148 in anxiety-like behavior as measured by the elevated plus maze (EPM).

149 Utilizing the elevated plus-maze (EPM) after exposure to escapable sho

150 Prior undrugged exposure to the elevated plus-maze (EPM) alters future behavioral strate

151 n increased exploratory behavior in both the Elevated Plus-maze (EPM) and the Black and White (B-W) t

152 assessed using a dry land maze (DLM) and an elevated plus-maze (EPM) at 4-month intervals.

153 The EZM paradigm has advantages over the elevated plus-maze (EPM) paradigm with respect to measur

154 ulation and CatWalk-gait analysis), anxiety (elevated plus maze, EPM) and depression (sucrose prefere

155 ry of MS15 would display less anxiety in the elevated plus maze (EPMZ) and novelty-suppressed feeding

156 mUcn treated rats tested in the elevated plus maze following the delayed pretreatment in

157 ng memory, a water maze task for escape, the elevated plus maze for anxiolytic/anxiogenic effects, pl

158 .e., sucrose preference) and aversive (i.e., elevated plus-maze, FST) circumstances was then assessed

159 ing multiple stressors including open-field, elevated plus maze, holeboard, light-dark box and novel

160 hile enhancing anxiety-like responses in the elevated plus maze in adulthood.

161 ly increased anxiety-related behavior in the elevated plus maze in both acutely and repeatedly restra

162 me spent on and entries into open arms of an elevated plus maze in both saline- and cocaine-treated g

163 sessed anxiety-like behavior by means of the elevated plus maze in control adult rats and in adult ra

164 lic indices, and exploratory behavior on the elevated plus maze in male C57BL/6J mice.

165 es to unconditioned nociceptive stimuli, and elevated plus maze in Sprague Dawley male rats, and in t

166 decreased rats' open-arm exploration in the elevated plus-maze in both male and female rats.

167 rances and time spent in the open arm of the elevated plus-maze in both sexes and ages.

168 pups (sensitization) but reduced fear in the elevated plus-maze in both sexes.

169 with increased anxiety-like behavior in the elevated plus maze, increases following footshock, and u

170 ng spent more time in the closed arms of the elevated plus maze, indicating anxiety-like behavior.

171 and spent less time in the open arms of the elevated plus maze, indicating high levels of innate fea

172 The avoidance test and elevated plus maze induced prominent Fos-LI in select br

173 (KO) mice were tested in locomotor monitors, elevated plus maze, inhibitory avoidance, acoustic start

174 The elevated plus maze is a widely used behavioral assay for

175 ing BLA beta-adrenergic signaling during the elevated plus maze is crucial for preventing this stress

176 suppressed and anxiety-like behavior in the elevated plus maze is dampened.

177 ustic startle response, prepulse inhibition, elevated plus-maze, light <--> dark exploration, Morris

178 n anxiety-like behavior, as reflected in the elevated plus-maze, light-dark box, and novel open field

179 ing for anxiety-related behaviours using the elevated-plus maze, light-dark box, and novelty-suppress

180 ment 2, a battery of anxiety-like behaviors (Elevated Plus Maze, Marble Burying, and Novelty Induced

181 o showed markedly reduced levels of anxiety (elevated plus maze, marble burying, novelty suppressed f

182 wing oral administration in mice in both the elevated plus maze model of anxiety (ED50 = 0.5 mg/kg) a

183 In standard behavioral tests (open field and elevated plus maze), mRGC activation induced behaviors c

184 In the elevated plus maze, mUcn 3 injections significantly incr

185 with innate anxiety-related behavior on the elevated plus maze (n = 20) but positively with expressi

186 ing the following tests: Light Dark Latency, Elevated Plus Maze, Novel Object Recognition, and Barnes

187 ed by increased anxiety-like behavior on the elevated plus maze on GD18.

188 t females displayed decreased anxiety on the elevated plus maze on GD9 compared to NP females, follow

189 e exhibited an anxiety-like phenotype in the elevated plus maze, open field, and light/dark box tests

190 cacy was assayed using the forced swim test, elevated plus maze, open field, marble burying, and nove

191 ry wheel running on behavior measures in the elevated plus maze, open field, social interaction and c

192 R mice showed lower levels of anxiety in the elevated plus maze, opposing the known high anxiety in c

193 unconditioned anxiety-like responses in the elevated plus maze or basal acoustic startle amplitude.

194 exposed to single-trial fear conditioning or elevated plus maze or sacrificed for basal diurnal corti

195 s have no effect on open-arm behavior in the elevated plus-maze or changes in startle reactivity indu

196 en field activity, open arm avoidance on the elevated plus-maze or conditioned place preference for c

197 no changes in anxiogenic behavior using the elevated plus maze (p>0.05).

198 spatial and nonspatial learning and memory, elevated plus maze performance, electrophysiological mea

199 wn at puberty decreased open arm time on the elevated plus maze post-pubertally (62%, P < 0.0001) in

200 f BNST(DL)-CRF neurons were performed before elevated plus maze, predator odor exposure, shock-induce

201 Behavior analyses by open field test, elevated plus maze, Reciprocal Social Interaction, and a

202 , and decreased time in the open arms of the elevated plus maze relative to control mice.

203 In the elevated plus maze, SERT-/- mice demonstrated anxiety-li

204 ng successive alleys (a modified form of the elevated plus-maze), social interaction, and hyponeophag

205 osing effects on exploratory behavior in the elevated plus-maze, somatic mechanical threshold, and th

206 eir behavior, we assessed the open field and elevated plus maze spatiotemporal patterning of activity

207 In the present study, we used elevated plus-maze, startle and prepulse inhibition, ope

208 iology of SCA1 mood alterations, we used the elevated-plus maze, sucrose preference and forced swim t

209 ar to those found at 8 weeks, but not in the elevated plus maze suggesting a temporal effect of wheel

210 xhibit reduced anxiety-like behaviors in the elevated plus maze task and deficits in cued and context

211 In the elevated plus maze task, we found that HT mice after sei

212 scrimination were assessed in an appetitive, elevated plus-maze task in 4 groups of mice: knockout mi

213 the cued fear-conditioning, open field, and elevated plus maze tasks.

214 igher anxiety response in the open-field and elevated plus-maze tasks.

215 eatment induced anxiety-like behavior in the elevated plus maze test and elevated intracranial self-s

216 ice showed less anxious-like behavior on the elevated plus maze test and had higher spontaneous recov

217 anxiety-like behavior and exploration in the elevated plus maze test and sexual behavior.

218 ehavior recognition system (PhenoTyper), the Elevated Plus Maze test and the Forced Swimming tests.

219 -type mice in the open field test and in the elevated plus maze test of anxiety.

220 eflects mouse affective state during virtual elevated plus maze test using two-photon calcium imaging

221 ced activity and reduced open arm time in an elevated plus maze test which can be consistent with anx

222 In the elevated plus maze test, administration of anti-SVG-30 e

223 hanges in behavioral tests (open field test, elevated plus maze test, chimney test, T maze test, and

224 decreased time spent in the open arm of the Elevated Plus Maze test, compared to control animals.

225 ed to the contextual fear conditioning test, elevated plus maze test, forced swim test, and tail susp

226 linical rodent models of anxiety, namely the elevated plus maze test, open field test, and food neoph

227 exploration or anxiety-like behavior in the elevated plus maze test.

228 state that was measured 7 days later in the elevated plus maze test.

229 thdrawal (situational anxiety) model and the elevated plus maze test.

230 thdrawal (situational anxiety) model and the elevated plus maze test.

231 d anxiety-related behaviors evaluated by the elevated plus maze test.

232 Locomotor activity and elevated plus maze test/forced swim test were conducted

233 etween trait anxiety levels evaluated by the elevated plus-maze test and CeA/LA activity.

234 s with or without BDNF coinfusion, using the elevated plus-maze test and two-bottle free-choice parad

235 s disease transgenic mice were tested in the elevated plus-maze test of anxiety at 6, 8, 10 and 12 we

236 In the elevated plus-maze test, no significant effects were det

237 activity and differences from control in the elevated plus-maze test.

238 n) and GR(wt/Qn) mice were confirmed by the "elevated plus maze" test in which GR(Qn/Qn) and GR(wt/Qn

239 r did transgenicity affect anxiety levels in elevated plus-maze testing.

240 d swimming tests), anxiety (black and white, elevated plus maze tests), aggressiveness (resident-intr

241 In both open field and elevated plus maze tests, socially isolated mice showed

242 iety-like behavior in the light-dark box and elevated plus maze tests, whereas SST(DeltaGHR) females

243 ion, sucrose preference, tail suspension, or elevated plus maze tests.

244 vaccination altered mouse behavior in T- and elevated plus-maze tests and simvastatin counteracted su

245 not alter behavior in the open field and the elevated plus-maze tests suggesting not only that the mo

246 -related indices in the novel open field and elevated plus-maze tests.

247 g PS rats were more motile in open field and elevated plus maze than control rats, and they learned f

248 ts to spend more time in the open arms of an elevated-plus maze than controls, indicating that inhibi

249 ice had a smaller heart rate increase in the elevated-plus maze than did wild-type littermates.

250 differences of anxiety-like behavior in the elevated plus maze that were correlated with BLA neurona

251 sed measures of anxiety-like behavior in the elevated plus maze, the light/dark box, and the open fie

252 une NZW control mice on 3 anxiety tasks: the elevated plus maze, the open-field drink test, and the n

253 -like reactivity was then measured using the elevated plus-maze, the defensive withdrawal test and ac

254 No changes were recorded in the elevated plus-maze, the light-dark transition, and defen

255 On Trial 1 in the elevated plus-maze, the receptor antagonists were withou

256 In addition, all rats were tested on an elevated plus maze to assess anxiety-like behavior and i

257 alongside a traditional measure of anxiety (elevated plus maze), to investigate the effects of juven

258 Examination of performance on the elevated plus maze under conditions designed to minimize

259 In the elevated plus maze, used to measure anxiety-like behavio

260 lec7a and the number of head dippings in the elevated plus maze was also noted in males born by CSD.

261 fear conditioning, yet baseline fear on the elevated plus maze was intact.

262 ield activity nor baseline exploration of an elevated plus-maze was affected by MTIP (1-10 mg/kg).

263 ortion of time spent on the open arms of the elevated plus-maze was found after 2.5 and 5 micrograms

264 , social defeat stress, forced swimming, and elevated plus maze) was assessed.

265 possibility, anxiety-related behaviors in an elevated plus maze were assessed in postpartum rats afte

266 Measures of anxiety-related behaviors in the elevated plus-maze were significantly (p < 0.05) decreas

267 s (tested in open field, marble burying, and elevated plus maze) were higher, which were alleviated b

268 6 of injections, subjects were tested on the elevated plus maze which provides a measure of anxiety,