ライフサイエンスコーパス: elongation

1 epetitive ubiquitin-to-ubiquitin attachment (elongation).

2 and additional glutamates can extend these (elongation).

3 A binds stress genes to retard transcription elongation.

4 d A site that markedly slow down or speed up elongation.

5 promoter DNA to commence the transition into elongation.

6 gulate neuronal homeostasis during defective elongation.

7 ssinosteroid signaling, to repress hypocotyl elongation.

8 Spt4 and regulates processive transcription elongation.

9 cells was also correlated to increased cell elongation.

10 anism that connects initiation to productive elongation.

11 ne first upper molar shows repeated anterior elongation.

12 could be involved in the control of alternan elongation.

13 to CDK9, a process key to HIV transcription elongation.

14 f specific proteins, by stalling translation elongation.

15 emical activities of WAVE1 on actin filament elongation.

16 ed fibers showed caliber reduction and nodal elongation.

17 ondary cell wall synthesis during plant cell elongation.

18 ption start site and promoting transcription elongation.

19 RNA template binds in the mode B site during elongation.

20 ctively slowing down the rate of translation elongation.

21 t site of transcription and transitions into elongation.

22 te also appeared to be important for polymer elongation.

23 that the exocyst complex promotes protrusion elongation.

24 es protein synthesis at a selective stage of elongation.

25 fficiency of non-canonical initiation equals elongation.

26 (hTR), a noncoding RNA required for telomere elongation.

27 ring tRNA binding and inhibiting translation elongation.

28 ociated with reductions in forewing size and elongation.

29 e regulation of transcription initiation and elongation.

30 affect charging but greatly attenuated chain elongation.

31 wo (Gln(700) and Tyr(717)) promoted alternan elongation.

32 imulation of BR biosynthesis to promote root elongation.

33 A(i)(Met) immediately before transition into elongation.

34 e all reduced MT coherence and/or tumor cell elongation.

35 riming E2, Ubc6, while both E3s use Ubc7 for elongation.

36 ratory to an elastic ECM drive valve leaflet elongation.

37 1A controls Tsix half-life and transcription elongation.

38 ale structural rearrangements during protein elongation.

39 redominantly attributed to variation in cell elongation.

40 translation initiation, gating entrance into elongation.

41 a2 aggregates through primary nucleation and elongation.

42 as high GC in the transcription bubble slows elongation.

43 and then extend by stretching during embryo elongation.

44 nodeficiency Virus (HIV) perturb translation elongation.

45 urprisingly similar to canonical translation elongation.

46 TCP transcription factors in stamen filament elongation.

47 ease of mRNAs from ribosomes via translation elongation.

48 establishment of neuronal polarity and axon elongation.

49 aves space in the active-site cavity for RNA elongation.

50 d pollen germination frequency and slowed PT elongation.

51 ady-state length or ciliary force-induced SF elongation.

52 all tracts do not generate the same rate of elongation.

53 ubunit rotation that accompanies translation elongation.

54 s additional mechanisms to inhibit hypocotyl elongation.

55 ltimately limits the rate of formin-mediated elongation.

56 ing, abortive synthesis, and transition into elongation.

57 h nucleotide addition cycle in transcription elongation.

58 to promote Pol II's transition to productive elongation.

59 to drive global polarized forces and tissue elongation.

60 +/- 12.79 MPa and Zn-0.8Li-0.8Mn alloy with elongation 103.27 +/- 20%.

61 fbl17 In addition, through analyses of root elongation, accumulation of cell death, and occurrence o

62 ortant for polymerase de novo initiation and elongation activities and essential for viral replicatio

63 iption initiation, promoter escape and early elongation activities of Pol II.

64 e in SHAM + FD animals (-5.5 D and 40 mum of elongation after 14 days of FD), and reflected exaggerat

65 as associated with increased five-year axial elongation after adjustment for baseline axial length in

66 Human gastruloids undergo elongation along an anteroposterior axis, and we use spa

67 ome shortening (anaphase A) and pole-to-pole elongation (anaphase B).

68 RDH genes and is required for further RNAPII elongation and 3'-end processing.

69 causes a genome-wide defect in transcription elongation and a global reduction of CTD Ser2 and Ser5 p

70 tin)-scaffolded acroplaxome during spermatid elongation and abnormal head morphologies in mature sper

71 nalysis we find that stretch-induced nuclear elongation and alignment perpendicular to the stretch ve

72 ntains missing-wedge artifacts, presented as elongation and an anisotropic resolution.

73 trinsically disordered proteins control cell elongation and carbon reserves via an order-by-disorder

74 olves coordinated adjustment of spatial cell elongation and cell flux.

75 rawl on solid surfaces through a sequence of elongation and contraction movements.

76 P1R35, is suggested to function in centriole elongation and conversion to centrosomes.

77 ile strength, and increased CG increased the elongation and decreased the young's modulus of the film

78 ddition, NlpI seems to contribute both to PG elongation and division biosynthetic complexes based on

79 m the regulation of enzymes involved in cell elongation and division.

80 ogenic processes that are distinct from cell elongation and division?

81 inducing responses such as accelerated shoot elongation and early flowering.

82 s, is characterized by hypocotyl and petiole elongation and hyponastic growth at the seedling stage.

83 ELL2 stimulates transcriptional elongation and is a subunit of the Super Elongation Comp

84 ionary success is largely attributed to neck elongation and its impact on feeding efficiency.

85 Whereas, they decline the elongation and loss factor.

86 oroid at 11 years of age predicted axial eye elongation and myopia during adolescence.

87 quality control mechanism during translation elongation and suggest that translational signaling path

88 hat DNA suppresses CMG ubiquitylation during elongation and that this suppression is relieved when CM

89 A polymerase is unchanged, the efficiency of elongation and the final mRNA output is higher when PQS

90 fine roots showed rapid re-establishment of elongation and water uptake capacity and we found that s

91 associated with greater subsequent axial eye elongation and with increased risk of incident myopia at

92 d for normal cell production and normal cell elongation, and its natural genetic variation is involve

93 hey regulate dendritic spine formation, axon elongation, and pontine midline crossing in a FEZF2-depe

94 1-GEF kalirin-7 regulated spinule formation, elongation, and recurrence.

95 rd), torsion (clockwise, counter-clockwise), elongation, and shortening.

96 es and factors to ensure correct initiation, elongation, and termination of mRNA transcription.

97 on messenger RNA (mRNA)-specific initiation, elongation, and termination rates.

98 oteins involved in transcription initiation, elongation, and termination, several noncoding (nc)RNAs

99 three major steps of translation-initiation, elongation, and termination-cells use stimuli to tune tr

100 of recruitment to promoter DNA, initiation, elongation, and termination.

101 omeric origin firing does not cause telomere elongation, and the role of Rif1 in regulating origin fi

102 athway that responds to interruptions during elongation, and we present structures at 3.1- to 3.3-ang

103 The process of transcription initiation and elongation are primary points of control in the regulati

104 stress fibers and their respective impact on elongation are unclear.

105 Strikingly, the enhanced elongation arises from the transcription-induced R-loop

106 reased interaction with active transcription elongation-associated factors in embryonic stem cells (E

107 high toughness (112 MJ m(-3)), and very high elongation at break (>900%).

108 yclohexene carbonate), is limited by its low elongation at break and high brittleness.

109 The elongation at break and the water vapor permeability (WV

110 al fate that is required for sustained axial elongation, at the expense of the neural fate(3,5).

111 POT1 alterations cause rapid telomere elongation, ATR kinase activation, telomere fragility, a

112 lly characterized for their function in cell elongation, but it is becoming clear that they play majo

113 TPP1 is required for telomere stability and elongation, but its role in establishing a telomere leng

114 I TCPs modulate GA-dependent stamen filament elongation by direct activation of SAUR63 subfamily gene

115 2 domain tune the efficiency of FH1-mediated elongation by directly regulating the rate of monomer in

116 DK9 and cyclin T, stimulates transcriptional elongation by RNA polymerase (Pol) II and regulates cell

117 actor that directly stimulates transcription elongation by RNA polymerase II.

118 iquitylation is tightly repressed throughout elongation by the Y-shaped DNA structure of replication

119 nding on the initiation kinetics, stochastic elongation can either enhance or suppress cell-to-cell v

120 Among all of the Super Elongation Complex (SEC) components, ELL1 (also known as

121 nal elongation and is a subunit of the Super Elongation Complex (SEC) essential for HIV-1 transactiva

122 ption elongation defects seen with the super elongation complex inhibitor KL-2 are exacerbated in DOT

123 es in dinucleotide production, transcription elongation complex stability, and Pol I pausing in vitro

124 h and disengages when needed to generate the elongation complex.

125 riven mechanism that reactivates backtracked elongation complexes and thus helps suppress their inter

126 Pol I elongation complexes are less stable than Pol II elongat

127 gation complexes are less stable than Pol II elongation complexes, and Pol I is more error prone than

128 n is not inhibited by arrested transcription elongation complexes.

129 nd DNA and dissociates stalled transcription elongation complexes.

130 s differences between priming/initiation and elongation complexes.

131 oter as initiating complexes transition into elongation complexes.

132 bly of abnormally long-lived (i.e., stalled) elongation complexes.

133 A mathematical model for RNAPI elongation confirmed the importance of nascent RNA foldi

134 ll-fate determination and in transcriptional elongation control.

135 ve transcription machinery, and 'ejects' the elongation corepressor ZMYND11(8,9).

136 ydroxyacyl dehydratation step of late FAS-II elongation cycles during keto-MA biosynthesis.

137 t in transcription elongation, transcription elongation defects seen with the super elongation comple

138 rmore, in Arabidopsis, KAR-induced root hair elongation depends on ACS7 Thus, we reveal a connection

139 Root elongation depends on the action of the gibberellin (GA)

140 verse processes, including PG turnover, cell elongation/division, and antibiotic resistance.

141 to control the rate and duration of spindle elongation during anaphase is poorly understood.

142 is was conducted to investigate spatial root elongation during hydrotropic response.

143 on, oestrogen, which is essential for ductal elongation during puberty, upregulates CCR1 expression o

144 regulation at each step, from initiation to elongation dynamics, produce qualitatively distinct sign

145 ., TFIID, TFIIH, and Mediator), pausing, and elongation (e.g., DSIF, NELF, PAF, and P-TEFb).

146 s new measures of translation initiation and elongation efficiencies, emphasizing the importance of r

147 is marked by co-localization of the negative elongation factor (NELF) complex and facilitated by PU.1

148 evating levels of the positive transcription elongation factor (P-TEFb), instating a large proliferat

149 s have indicated that eukaryotic translation elongation factor 1 delta (eEF1D) may associate with RNP

150 re we show that, when acetylated, eukaryotic elongation factor 1A1 (eEF1A1) negatively regulates PNS

151 ssociated hyperphosphorylation of eukaryotic elongation factor 2 (eEF2) was blunted with selective AM

152 is in a mouse liver by targeting translation elongation factor 2 (eEF2) with RNAi.

153 ed diphtheria toxin (DT), which binds to the elongation factor 2 and blocks protein synthesis, can sp

154 tein 5 (WBP5), also known as Transcriptional Elongation Factor A like 9 (TCEAL9) has been proposed as

155 the translation initiation factor initiation elongation factor alpha (eIF2alpha).

156 The positive transcription elongation factor b (P-TEFb), composed of CDK9 and cycli

157 ivators BRD4 and MED1, and the transcription elongation factor CDK9 for transcription.

158 A2, encoding the tissue-specific translation elongation factor eEF1A2, have been shown to cause neuro

159 beak, two binding regions of the eukaryotic elongation factor eEF2.

160 each aminoacyl-tRNA that is delivered by the elongation factor EF-Tu(1).

161 complex (CTK complex) is known as a positive elongation factor for many inducible genes by releasing

162 led into subunits by two conserved proteins, elongation factor G (EF-G) and the ribosome recycling fa

163 , ribosome-recycling factor (RRF) and GTPase elongation factor G (EF-G), synergistically split 100S r

164 ly of proteins that bind to the drug target (Elongation factor G [EF-G]) and promote dissociation of

165 s or through the inhibition of mitochondrial elongation factor G1 (mEF-G1) progressively compromised

166 This universally conserved transcription elongation factor is known as Spt5 in archaeal and eukar

167 ion is independent of positive transcription elongation factor P-TEFb.

168 interaction with the positive transcription elongation factor P-TEFb.

169 as temporary backtracking and transcription elongation factor S-II (TFIIS)-dependent RNA cleavage, o

170 ancy and high occupancy of the transcription elongation factor Spt4/Spt5 suppresses TC-NER in Rad26-d

171 The transcription elongation factor Spt5 is conserved from bacteria to hum

172 The elongation factor TFIIS stimulates the intrinsic transcr

173 L1 (also known as ELL) is the only bona fide elongation factor that directly stimulates transcription

174 osomal translation, the translational GTPase elongation factor Tu (EF-Tu) delivers a transfer RNA (tR

175 in protein synthesis is a ternary complex of elongation factor Tu (EF-Tu), aminoacyl-tRNA (aa-tRNA),

176 ly contain mutations in the gene encoding an elongation factor, FusA1.

177 -neurons, we focus here on the role of actin elongation factors as potential regulators of developmen

178 und that regrowth in vivo requires the actin elongation factors Ena and profilin, but not the formins

179 pre-termination complex" (PTC) with RNAP and elongation factors NusA and NusG, which stabilize the PT

180 age and remodel nucleosomes or transcription elongation factors that facilitate Pol II nucleosome byp

181 d 30S ribosomal protein subunit variants and elongation factors were positively correlated with hour

182 fication enzymes, translation-initiation and elongation factors, and ribosomal proteins.

183 majority of organisms possess transcription elongation factors, the functionally similar bacterial G

184 concentration dependent interactions between elongation factors, tRNAs, ribosomes, and other factors

185 esis activities that required initiation and elongation factors.

186 Additionally, shell elongation from the umbo, a metric often overlooked, is

187 trol during oxidative stress, which supports elongation halt at pretranslocation.

188 sing the CdS shell volume through the length elongation has no effect on either the peak wavelength o

189 l details have provided insights into linear elongation; however, molecular details like the C-termin

190 we uncover as a novel regulator of centriole elongation in human cycling cells.

191 UB1 deletion, ISC1 deletion prevents spindle elongation in hydroxyurea-treated cells.

192 The results suggest RA changes with axial elongation in myopia to compensate for reduced retinal g

193 ly, to integrate chilling tolerance and cell elongation in rice (Oryza sativa) (FSD2, Fe-superoxide d

194 of RNA polymerase II (Pol II) transcription elongation in vitro.

195 has been shown to stimulate transcriptional elongation in vitro.

196 bal transcription profiles and transcription elongation in vivo.

197 coding a DL-endopeptidase important for cell elongation, in the ugtP mutant background produced cells

198 y RNA polymerase (RNAP) during transcription elongation, in which a translocating RNAP uses a "steppi

199 However, how neck elongation influenced exactly on feeding strategies is s

200 nt shows hypersensitivity to the translation elongation inhibitor cycloheximide, suggesting that VIG1

201 These assays often use elongation inhibitors to purportedly inhibit the release

202 ciate from ribosomes even in the presence of elongation inhibitors.

203 itment to viral genes but also by control of elongation into viral gene bodies.

204 Moreover, we show that low N-induced root elongation is associated with aboveground N content and

205 We identify that mitotic centriole over-elongation is dependent on mitotic Polo-like kinase 1, w

206 proximally paused RNA Pol II into productive elongation is essential for gene expression.

207 at enhancers and that active transcriptional elongation is essential to maintain H3K27ac abundance.

208 ) seedlings are grown in the dark, hypocotyl elongation is promoted, whereas root growth is greatly r

209 While translation elongation is well studied in bacteria and yeast, less i

210 Variation in translation-elongation kinetics along a transcript's coding sequence

211 ributes to variability in translation rates, elongation kinetics are causally encoded in the primary

212 t transcription of antisense ncRNAs induces 'elongation marks' on histones in promoter regions.

213 fied, and its potential participation in the elongation mechanism is discussed.

214 We compared the elongation mechanism of Cps1B with that of a DeltaTPR tr

215 er-free, comprehensive description of fibril elongation of Abeta(16-22) and how it is modulated by ph

216 uts of active transport, initiated by nearby elongation of actin filaments.

217 of domain V and contributing to a processive elongation of alternan chains.

218 the bound dinitrogen species, as well as the elongation of either the Mo-O5 (carboxyl) or Mo-O7 (hydr

219 The result supported the idea that elongation of glycan chains has to proceed from the redu

220 iption factors are required for an efficient elongation of hypocotyls in response to auxin and for th

221 However, the elongation of hypocotyls in response to auxin was impair

222 in why only the upper first molar reacts via elongation of its anterior part.

223 Xrn1 modulates transcription initiation and elongation of its target genes.

224 nes show a unique function in regulating the elongation of showy ventral ligules that play a major ro

225 The replication and elongation of telomeres requires the disruption of these

226 iles displayed by Cps1B suggested processive elongation of the nascent polymer, whereas Cps1B-DeltaTP

227 sphere reorganization energy by limiting the elongation of the O-O bond upon reduction.

228 er 14 days of FD), and reflected exaggerated elongation of the posterior vitreous chamber.

229 While axial elongation of the rare trigonal-prismatic geometry stabi

230 c enhancement will result from further axial elongation of these nanoribbons, which can be readily en

231 lation in vivo Overexpressed Rspo2 inhibited elongation of Xenopus ectoderm explants and Erk1 activat

232 in electrical performance even under extreme elongations of 500% are described.

233 Pol II occupancy on viral DNA and to promote elongation on late genes later in infection.

234 pecifically address the role of faceting and elongation on the magnetic shape anisotropy.

235 ble actomyosin bundles, e.g., focal adhesion elongation or migratory front-back polarization.

236 ally to function by modulating transcription elongation or translation initiation.

237 This formin mediates slow filament elongation owing to a high probability of profilin bindi

238 elements similar to those for transcription-elongation pausing.

239 consensus sequence element for transcription-elongation pausing.

240 ior to the transition from initiation to the elongation phase of translation, thus blocking further i

241 ed during the contraction but not during the elongation phase, whereas P cells were unaffected throug

242 These results lead us to suggest that embryo elongation plays a causal role in timing the exposure of

243 ic columnar polymer, exhibiting a nucleation-elongation polymerization mechanism.

244 rectly impacts the kinetics of transcription elongation prior to the sequence entering the active sit

245 Moreover, stability of the chain elongation process was evaluated by performing repeated

246 actosamine repeat as a key step of the chain elongation process.

247 e influence of DNA sequence on transcription elongation properties of eukaryotic RNA polymerase I (Po

248 rofilin is tethered to the formin alters the elongation rate by modulating profilin occupancy at the

249 itive feedback loop, which sustains a shared elongation rate for coupled tissues.

250 al phenomena, such as the increasing peptide elongation rate with bacterial growth rate, are predicte

251 ium imaging confirmed the strong increase in elongation rate, in comparison with the condition of tip

252 The temporal trend of leaf elongation rate, used as a proxy for that of xylem water

253 ubule-binding domains to control the spindle elongation rate.

254 re involved in regulation of transcriptional elongation rate.

255 pecially reflected in a decreased fibril-end elongation rate.

256 nstrumental in promoter-proximal pausing and elongation-rate control.

257 with reduced processivity and normal Pol II elongation rates have normal polyadenylation profiles.

258 sely, cells containing derivatives with fast elongation rates show a subtle downstream shift in poly(

259 demonstrate that inhibitory codon pairs slow elongation rates which are partially rescued by increase

260 nvestigate the relations between translation elongation rates, (aminoacyl-) tRNA levels, and codon us

261 ny genes are sensitive to both fast and slow elongation rates, and a global shift of poly(A) utilizat

262 system to tune midzone activity and control elongation rates.

263 al strength (measured by force to punch) and elongation ratio and circularity ratio linked to damage

264 ecture with multiscale statistics describing elongation ratios, circularity ratios, vein density, and

265 calculations show that the Pb-I bond length elongation reduces the overlap of the Pb s- and I p-orbi

266 ts became more 'organized' after IAA stopped elongation, refuting the hypothesis that 'more organized

267 tart codon initiation and N-terminal peptide elongation, regulating ribosome occupancy of these codon

268 sults in either transcription termination or elongation rescue, which rely on ATP-dependent Mfd trans

269 CP14 and TCP15 are required for an efficient elongation response to auxin, most likely by regulating

270 s showed significant reduction of their root elongation response to low N, suggesting a systemic stim

271 al switching in the context of transcription elongation, RNA folding, and ligand binding.

272 ynthesis complexes that function during cell elongation (RodA-PBP2) and cell division (FtsW-FtsI), an

273 trength of 1,300 megapascals and 10 per cent elongation, showing superior mechanical properties to th

274 as target (T vs P) and phase (contraction vs elongation) specific, and prevented self-generated signa

275 Thus, Pol II elongation speed is important for poly(A) site selection

276 Translation-elongation speed is influenced by molecular factors with

277 Comparison with the likely elongation state, seen in two structures of pneumovirus

278 n, whereas the burst of RNAs produced during elongation stimulate condensate dissolution.

279 Recent studies on transcription elongation suggest different mechanistic roles in yeast

280 with high levels of oleic acid available for elongation, suggesting that the Pennycress FAE1 enzyme s

281 ther PP4 or PP1 govern pause release and the elongation-termination transition, respectively.

282 DOT1L in promoting productive transcription elongation that is independent of H3K79 methylation.

283 gator complex, which catalyses translational elongation through tRNA modifications at the wobble (U(3

284 the developmental transition from rapid cell elongation to secondary cell wall synthesis.

285 hich link regulation of RNAPII transcription elongation to suppression of aberrant initiation.

286 ltaneous observation of dozens of viral RdRp elongation traces on kilobases long templates, and this

287 itself has no major defect in transcription elongation, transcription elongation defects seen with t

288 hat contributes to natural variation of root elongation under low N.

289 s with cell apical area to limit larger cell elongation under mechanical stress.

290 where it later engages in full transcription elongation upon major ZGA (production).

291 fread errors of transcription and to restart elongation via stimulation of RNA hydrolysis by the acti

292 gnaling emerges that is required for explant elongation via the planar cell polarity (PCP) pathway.

293 p it is necessary to visualize GTP-catalysed elongation, which has remained a challenge(2-4).

294 SV polymerase catalyzed primer-dependent RNA elongation with different lengths of primers on both sho

295 Inhibiting protein elongation with SVC112 reduces tumor growth in head and

296 ot apical meristem and cortical cells in the elongation zone confirmed that roots are autonomous for

297 umulation and callose deposition in the root elongation zone under Pi deficiency increased with LAC2-

298 dation, is required in both the meristem and elongation zone.

299 the root meristem and cell expansion in the elongation zone.

300 tion zone" boundary between the division and elongation zones is critical for efficient root growth;