コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 iated with hyper-phosphorylation of the Spt5 elongation factor.
2 me O-GlcNAcase (OGA) as an RNA polymerase II elongation factor.
3 esis activities that required initiation and elongation factors.
4 are aided by a collection of proteins called elongation factors.
5 anslation initiation factors and translation elongation factors.
7 the translation elongation factor eukaryotic elongation factor 1 alpha (eEF1A) is necessary for AID c
8 NA), as well as fragments of the translation elongation factor 1 alpha (EF-1alpha) and actin (Act) ge
9 rometry (LC-MS/MS)-based proteomics revealed elongation factor 1 alpha (EF1a) as a protein binding to
10 beta-actin (Actin), beta-tubulin (Tubulin), elongation factor 1 alpha (EF1alpha), glyceraldehyde-3 p
11 re we discovered that eukaryotic translation elongation factor 1 alpha 1 (eEF1A1) interacted with PpI
12 s have indicated that eukaryotic translation elongation factor 1 delta (eEF1D) may associate with RNP
14 ted and disulfide-bonded proteins, including elongation factor 1-alpha1 and mouse serum albumin, and
17 drial fission factor (Mff) and mitochondrial elongation factor 1/2 (MIEF1/2) interact with and recrui
20 d cellular WW domain proteins and eukaryotic elongation factor 1A (eEF1A) in control of activation of
22 -like 13) dimethylation of eEF1A (eukaryotic elongation factor 1A) lysine 55 (eEF1AK55me2) is utilize
24 -affinity probe, we identify the translation elongation factor-1A ternary complex (eEF1A.GTP.aminoacy
25 re we show that, when acetylated, eukaryotic elongation factor 1A1 (eEF1A1) negatively regulates PNS
26 We discovered that a C parvum translation elongation factor 1alpha (CpEF1alpha) was discharged fro
28 e to an enhanced interaction with Eukaryotic Elongation Factor 1alpha (EF1alpha), whose protein level
30 by phosphorylating its substrate, eukaryotic elongation factor 2 (eEF-2), thereby reducing its affini
31 diphthamide on human eukaryotic translation elongation factor 2 (eEF2) is the target of ADP ribosyla
32 through inhibition of eukaryotic translation elongation factor 2 (eEF2) via adenosine diphosphate (AD
33 ssociated hyperphosphorylation of eukaryotic elongation factor 2 (eEF2) was blunted with selective AM
34 ing protein (Tbp) and eukaryotic translation elongation factor 2 (Eef2) were not affected by inflamma
36 In the periphery, OXT activates eukaryotic elongation factor 2 (eEF2), an essential mediator of pro
37 n this study, we demonstrate that eukaryotic elongation factor 2 (eEF2), which catalyzes the GTP-depe
38 controlled by phosphorylation of eukaryotic elongation factor 2 (eEF2), which inhibits its activity
39 lation of mRNA translation factor eukaryotic elongation factor 2 (eEF2), which results in inhibition
42 ), beta actin (ACTB), eukaryotic translation elongation factor 2 (EF2), glyceraldehyde-3-phosphate de
43 chanism of action, inhibition of translation elongation factor 2 (PfEF2), led to progression of 2 (DD
44 reduced phosphorylation levels of eukaryotic elongation factor 2 and also requires the presence of el
45 ed diphtheria toxin (DT), which binds to the elongation factor 2 and blocks protein synthesis, can sp
49 plitudes by reducing postsynaptic eukaryotic elongation factor 2 kinase (eEF2K) activity subsequent t
52 protein synthesis by inactivating eukaryotic elongation factor 2 kinase (eEF2K), which, when active,
54 modification of histidine 715 in eukaryotic elongation factor 2, resulted in tagraxofusp resistance.
56 induced the phosphorylation of a eukaryotic elongation factor-2 (eEF-2) kinase, radiation sensitivit
60 in the LYST ARM/HEAT (armadillo/huntingtin, elongation factor 3, protein phosphatase 2A, and the yea
61 the N-terminal HEAT (named after Huntingtin, elongation factor 3, protein phosphatase 2A, and yeast k
62 domains, consisting of six (A-F) Huntingtin, elongation factor 3, protein phosphatase 2A, target of r
63 Despite numerous studies, the function of elongation factor 4 (EF-4/LepA), a highly conserved tran
65 tein 5 (WBP5), also known as Transcriptional Elongation Factor A like 9 (TCEAL9) has been proposed as
66 Brain Expressed X-Linked (Bex)/Transcription elongation factor A-like (Tceal) superfamily members Bex
68 transcription regulation shapes translation elongation factor activity and exposes how eEF2 is integ
69 h the regulated binding of the transcription elongation factor AFF3 between a DMR and an enhancer.
73 stitutively evicts Spt5, a key transcription elongation factor and TC-NER repressor, from the chromat
74 , which recruits the selenocysteine specific elongation factor and tRNA(Sec) needed to reassign the U
75 action of the sarcin ricin loop with the two elongation factors and (iii) networked information excha
78 so that it can serve as a platform for other elongation factors and maintain its association with RNA
80 ion initiation, whether cellular translation elongation factors are responsive to inflammation and in
82 e identified transcription pause-release and elongation factors as one set of in vivo-specific cancer
83 -neurons, we focus here on the role of actin elongation factors as potential regulators of developmen
84 Here, we identify TFIIS.h, a transcription elongation factor, as a new transcriptional target of p5
86 ed Atf4 binding regulated the association of elongation factors at both the promoter and the enhancer
87 de in the specialized positive transcription elongation factor b (P-TEFb) activation mechanism that i
88 by additional loss of positive transcription elongation factor b (P-TEFb) activity, a key factor in p
89 Pol II release, that positive transcription elongation factor b (P-TEFb) directly regulates the init
90 es the release of the positive transcription elongation factor b (P-TEFb) from the 7SK snRNP in a man
91 tor of transcription)-positive transcription elongation factor b (P-TEFb) interaction allowed for loc
94 d Tat protein hijacks positive transcription elongation factor b (P-TEFb) to phosphorylate and activa
95 ity by activating the positive transcription elongation factor b (P-TEFb) via its release from the in
97 s and inactivates the positive transcription elongation factor b (P-TEFb), an essential eukaryotic mR
98 es its binding to the positive transcription elongation factor b (P-TEFb), and potentiates its transc
100 CDK9, a component of positive transcription elongation factor b (P-TEFb), to target gene promoters,
103 ) to recruit the host positive transcription elongation factor b (pTEFb) complex onto the viral trans
105 with both 7SK RNA and positive transcription elongation factor b are critical for HEXIM1 subdiffusion
106 DK9, the component of positive transcription elongation factor b complex responsible for Ser2 phospho
107 f Pol II pausing, and positive transcription elongation factor b releases (P-TEFb) paused complex aft
109 tion with the P-TEFb (positive transcription elongation factor b) kinase complex and for its recruitm
110 regulatory subunit of positive transcription elongation factor b, a complex that inhibits OL maturati
111 c A1 subunit (Stx2A1) binds to the conserved elongation factor binding C-terminal domain (CTD) of rib
112 he Arc gene, facilitating increased negative elongation factor binding to the Arc promoter and decrea
114 endent kinase 9 (CDK9), that regulates these elongation factors, blocked induction of the AA-responsi
115 ects by suggesting that codon recognition by elongation factor-bound aminoacyl-tRNA is initiated by h
119 ion to revealing insights into how these two elongation factors cooperate to promote RNAPII elongatio
121 ngation complex, EC*, encompassing the human elongation factors DSIF, PAF1 complex (PAF) and SPT6.
123 al P-stalk stimulates the GTPase activity of elongation factors during translation, we propose that t
124 activation of a top candidate RBP, negative elongation factor E (NELFE), via somatic copy-number alt
125 ognostic value, we have developed a Negative Elongation Factor E (NELFE)-Dependent MYC Target (NDMT)
126 n of a subset of proteins by ubiquitin chain elongation factors (E4), represented by Ufd2p in Sacchar
127 d seedlings recovered eukaryotic translation elongation factor (eEF) 1B (alpha-, beta-, and gamma-sub
128 e mutations in the gene encoding translation elongation factor eEF1A2 have recently been found to giv
129 A2, encoding the tissue-specific translation elongation factor eEF1A2, have been shown to cause neuro
130 ires diphthamide modification of translation elongation factor eEF2 and wobble uridine modifications
132 decreased phosphorylation of the eukaryotic elongation factor eEF2, reminiscent of the effects of ke
133 phosphorylation of the critical translation elongation factor eEF2, which catalyzes the protein synt
136 tively; (iii) deletion of efp, which encodes elongation factor EF-P that assists the translation of p
138 s is enhanced by surface-exposed translation elongation factor EF-Tu carrying a Lys-5 trimethylation,
140 parameters and the mechanistic strategies of elongation factor (EF) Ts-catalyzed nucleotide exchange
141 the nucleotide-dependent switch mechanism of elongation factor (EF) Tu as a prototypical molecular sw
144 entral domain of Nmd3 mimics the translation elongation factor eIF5A, inserting into the E site of th
145 tional modification of essential translation elongation factor eIF5A, mediated by deoxyhypusine synth
146 of regulating stability and functions of key elongation factor ELL for expression of diverse sets of
147 mplex (LEC)-which contains the transcription elongation factor ELL/EAF-was found to be required for t
148 affold proteins AFF1/4 and the transcription elongation factors ELL1/2 are core components of the sup
151 The RNA polymerase II (Pol II) transcription elongation factor, Elongin A (EloA), is methylated by PR
152 und that regrowth in vivo requires the actin elongation factors Ena and profilin, but not the formins
153 tention and demonstrate that the translation elongation factor eukaryotic elongation factor 1 alpha (
155 complex (CTK complex) is known as a positive elongation factor for many inducible genes by releasing
156 ing lumen formation, the actin nucleator and elongation factor, formin-like 3 (fmnl3), localizes to E
157 84% sequence identity with the corresponding elongation factor from Escherichia coli Interestingly, t
158 Thus, we show that different linear actin elongation factors function in distinct contexts even wi
160 The antibiotic fusidic acid (FA) targets elongation factor G (EF-G) and inhibits ribosomal peptid
161 led into subunits by two conserved proteins, elongation factor G (EF-G) and the ribosome recycling fa
162 bits bacterial protein synthesis by blocking elongation factor G (EF-G) catalyzed translocation of me
165 ation step of prokaryotic protein synthesis, elongation factor G (EF-G), a guanosine triphosphatase (
167 , ribosome-recycling factor (RRF) and GTPase elongation factor G (EF-G), synergistically split 100S r
168 rotated state is not a proper substrate for elongation factor G (EF-G), thus inhibiting translocatio
172 ly of proteins that bind to the drug target (Elongation factor G [EF-G]) and promote dissociation of
175 ve dissected early folding events of nascent elongation factor G, a multi-domain protein that require
178 some in complex with the human mitochondrial elongation factor G1 (EF-G1(mt)) in three distinct confo
179 s or through the inhibition of mitochondrial elongation factor G1 (mEF-G1) progressively compromised
181 e loop, acting in concert with initiation or elongation factors, guides the nontemplate DNA in transc
182 Our results show that Spt4/5 is a general elongation factor in archaea as its presence on all gene
183 of one gene, lepA, a translation-associated elongation factor, increased rifampicin tolerance in all
185 This universally conserved transcription elongation factor is known as Spt5 in archaeal and eukar
186 ation defect is explained by the loss of the elongation factors LEO1 and CDC73, part of PAF1 complex,
187 Bodian-Diamond syndrome that cooperates with elongation factor-like GTPase 1 (EFL1) to catalyze relea
188 biochemical methods and identified the actin elongation factor Mena as a novel GRASP65-binding protei
189 ning protein member X1)-TUFM (Tu translation elongation factor mitochondrial) protein complex, promot
191 these genes include the conserved cell wall elongation factors MreC and MreD(2,6,7), as well as a me
192 t polypeptides, the guanosine triphosphatase elongation factors mtEF-Tu and mtEF-G1, and the Oxa1L tr
193 and enrichment of the positive transcription elongation factors MYC, BRD4, PAF1, and the super elonga
194 did not impact the recruitment of other key elongation factors, namely, Spt5, Spt6, and the FACT com
196 and vertebrates, DSIF together with negative elongation factor (NELF) associates with RNA polymerase
197 is marked by co-localization of the negative elongation factor (NELF) complex and facilitated by PU.1
198 arly transcription, mediated by the negative elongation factor (NELF) complex, allows cells to coordi
199 PARP-1 ADP-ribosylates and inhibits negative elongation factor (NELF), a protein complex that regulat
200 II and prevents the release of the negative elongation factor (NELF), thus stabilizing Pol II promot
201 identify two new factors (BRD4 and negative elongation factor (NELF)-E) and to define their sites an
204 sly characterized genes (e.g., transcription elongation factor NusA and tumor necrosis factor alpha-i
205 pre-termination complex" (PTC) with RNAP and elongation factors NusA and NusG, which stabilize the PT
208 lier upon the binding of unrelated bacterial elongation factor NusG, suggesting that this may be a ge
217 nd MePCE captures the positive transcription elongation factor P-TEFb and prevents phosphorylation of
218 orks by activating the human transcriptional elongation factor P-TEFb, a CDK9-cyclin T1 heterodimer t
223 evating levels of the positive transcription elongation factor (P-TEFb), instating a large proliferat
226 ngation factors suggests that both conserved elongation factors play important roles in transcription
227 and late-stage transcription initiation and elongation factors, plus the capping and methylating enz
229 as temporary backtracking and transcription elongation factor S-II (TFIIS)-dependent RNA cleavage, o
230 bromo-adjacent homology and transcriptional elongation factor S-II domain, which we named REPRESSOR
231 dependent upon binding of the Sec-dedicated elongation factor SelB to a Sec insertion sequence (SECI
234 A striking expansion of the REF/SRPP (rubber elongation factor/small rubber particle protein) gene fa
235 We found that targeting the transcription elongation factor Spt4 selectively decreased production
237 ancy and high occupancy of the transcription elongation factor Spt4/Spt5 suppresses TC-NER in Rad26-d
238 ain bound to early ECs, while levels of core elongation factors Spt4-Spt5, Paf1C, Spt6-Spn1, and Elf1
239 histone H2B (H2Bub1) and phosphorylation of elongation factor Spt5 by cyclin-dependent kinase 9 (Cdk
241 the known RNA polymerase II (pol II) pausing/elongation factors SPT5 and TRIM28-KAP1-TIF1beta, and a
243 that the histone chaperone and transcription elongation factor Spt6 spatially and temporarily coincid
244 ing as a histone chaperone and transcription elongation factor, Spt6 counteracts repression by opposi
245 fic to S. pombe, that requires the conserved elongation factor subunit Spt4 and resembles promoter-pr
246 essentiality of both conserved transcription elongation factors suggests that both conserved elongati
247 that targeted reduction in the transcription elongation factor SUPT4H1/SUPT5H reduces both sense and
249 otein designated T. brevicorniculatum rubber elongation factor (TbREF) by using mass spectrometry to
250 using mycological culture, while translation elongation factor (TEF)-1alpha analysis of Fusarium isol
253 transcripts is coordinated by transcription elongation factors (TEFs) such as polymerase-associated
254 e used a mutant version of the transcription elongation factor TFIIS (TFIIS(mut)), aiming to specific
256 the vRNAP subunit Rpo30 resembles the Pol II elongation factor TFIIS, and that NPH-I resembles chroma
258 niversally conserved bacterial transcription elongation factor that binds RNA polymerase (RNAP).
259 DSIF or Spt4/5) is a conserved transcription elongation factor that both inhibits and stimulates tran
260 L1 (also known as ELL) is the only bona fide elongation factor that directly stimulates transcription
261 s of the roles of translation initiation and elongation factors that assist the ribosome in binding t
262 age and remodel nucleosomes or transcription elongation factors that facilitate Pol II nucleosome byp
263 Ena/VASP tetramers are processive actin elongation factors that localize to diverse F-actin netw
265 majority of organisms possess transcription elongation factors, the functionally similar bacterial G
267 sion are aminoacyl-tRNA synthetases (aaRSs), elongation factor thermo-unstable (EF-Tu), the ribosome,
268 ve opportunistic pathogen that trimethylates elongation factor-thermo-unstable (EF-Tu) on lysine 5.
269 istone-based chromatin and thus must rely on elongation factors to accelerate transcription through c
270 stone-modification enzymes and transcription elongation factors to aid transcription through nucleoso
271 omain-containing proteins, and transcription elongation factors to mediate chromatin remodeling and r
272 requires the recruitment of transcriptional elongation factors to rapidly induce innate response gen
273 terminal domain (CTD) of Pol II and negative elongation factors to release Pol II from promoter-proxi
274 concentration dependent interactions between elongation factors, tRNAs, ribosomes, and other factors
275 tations that alter the coiled-coil domain of elongation factor Ts (EF-Ts) and confer resistance to th
276 programmed ribosome in ternary complex with elongation factor Tu (EF-Tu) and GTP and then, again, in
277 receptor (EFR) recognizes the bacterial PAMP elongation factor Tu (EF-Tu) and its derived peptide elf
278 osomal translation, the translational GTPase elongation factor Tu (EF-Tu) delivers a transfer RNA (tR
281 ed with a ternary complex (TC) consisting of elongation factor Tu (EF-Tu), aminoacyl tRNA and GTP, an
282 in protein synthesis is a ternary complex of elongation factor Tu (EF-Tu), aminoacyl-tRNA (aa-tRNA),
290 n of aminoacyl-tRNAs in ternary complex with elongation factor Tu and GTP on messenger RNA-programmed
293 uginosa methyltransferase EftM trimethylates elongation factor-Tu (EF-Tu) on lysine 5 to form a post-
294 the long-term effects of Onc112 on ribosome, elongation factor-Tu (EF-Tu), and DNA spatial distributi
295 ultiple receptor-like kinases, including the ELONGATION FACTOR-TU RECEPTOR (EFR) and PEP1 RECEPTOR1 (
296 l genomes, and here we demonstrate that both elongation factors, via different mechanisms, can accele
297 XPD and TUFM, a mitochondrial Tu translation elongation factor was detected to be physically interact
298 d 30S ribosomal protein subunit variants and elongation factors were positively correlated with hour
300 s long been considered to be a transcription elongation factor whose ability to destabilize nucleosom