ライフサイエンスコーパス: elucidate

1 ms underlying this phenomenon continue to be elucidated.

2 .50 spherical equivalent) has not been fully elucidated.

3 r subunits in gene regulation have yet to be elucidated.

4 ineages to drive sorting have not been fully elucidated.

5 the optimal surgical approach has yet to be elucidated.

6 usal alterations preceding CRC have not been elucidated.

7 the elicitation of anaphylaxis remains to be elucidated.

8 The precise pathomechanisms remain to be elucidated.

9 ein-protein interaction (PPI), remains to be elucidated.

10 , many aspects of their biochemistry must be elucidated.

11 , as well as pathways that have not yet been elucidated.

12 gical functions in these cells have not been elucidated.

13 hronic kidney disease (CKD) has not yet been elucidated.

14 conventional plastics in food packaging are elucidated.

15 lls infiltrate into the kidney are not fully elucidated.

16 e rhizosphere microbiota remains to be fully elucidated.

17 roducts and mechanisms involved are not well elucidated.

18 involvement in cell damage have not yet been elucidated.

19 small RNAs inhibit translation has yet to be elucidated.

20 , and the mechanisms of cell entry have been elucidated.

21 d apoptosis signaling in cancer remain to be elucidated.

22 paration of [4+0]-tetraarylethenes (TAEs) is elucidated.

23 o cellular compartments has not been clearly elucidated.

24 at the junction areas remain insufficiently elucidated.

25 atrial alternans in HF remains incompletely elucidated.

26 such compounds act in concert remains to be elucidated.

27 ent of phage therapies, have yet to be fully elucidated.

28 onal pathways implicated have not been fully elucidated.

29 epatitis (AH), with the mechanisms yet to be elucidated.

30 ch FlrC regulates transcription is not fully elucidated.

31 proteins within this architecture have been elucidated.

32 t and their triterpene pathway products were elucidated.

33 Here, we elucidate a mechanism of action on intestinal epithelial

34 Together, our findings elucidate a novel and specific role for P2X5 as a critic

35 rons within multiple hypothalamic nuclei and elucidate a novel functional mechanism for the preoptic

36 Here, we elucidated a 3.4 angstrom resolution structure of Saccha

37 This study deeply elucidates a link between prolidase activity and neurona

38 Thus, these results elucidates a novel slow gain-control mechanism able to s

39 As a result, this study elucidates a role for TET2 in governing luminal cell dif

40 lity and photoreceptor degeneration, thereby elucidating a potential new therapeutic strategy to comb

41 equired for channel formation have yet to be elucidated, although a predicted helix-loop-helix (H-L-H

42 To meet this unmet medical need, we aimed to elucidate an additional pathway of chronic ocular GVHD.

43 c mechanism of the organic oxidases has been elucidated, and the high TOF is achieved through rapid i

44 al cristae has now, for the first time, been elucidated at a protonic bioenergetics level: 1) The for

45 live feeds and the ablation have never been elucidated at a transcriptome-wide level.

46 ctive loss of beta cells needs to be further elucidated but overall, our findings are not supportive

47 ion of aged liver grafts have not been fully elucidated, but mitochondrial dysfunction appears to be

48 sm of RPE65 protein regulation remains to be elucidated, but the current work suggests that high vect

49 It, however, has not been unequivocally elucidated by currently existing techniques based on ex

50 her hand, chromatin quantitative trait loci, elucidated by direct epigenetic profiling of specific hu

51 The patterning mechanism is elucidated by in-depth investigation of the photochemica

52 ion, the uptake mechanism is comprehensively elucidated by molecular dynamics simulation and density

53 peptides were purified and their structures elucidated by one and two-dimensional nuclear magnetic r

54 Their structures were elucidated by the comprehensive analyses of IR, mass spe

55 The detailed picture elucidated by this study may enable the rational design

56 Many cellular models aimed at elucidating cancer biology do not recapitulate pathobiol

57 sis of distinct cancers has the potential to elucidate carcinogenic mechanisms and inform broadly app

58 n) over varying evolutionary time scales, to elucidate changes in biochemical pathways of energy meta

59 in three-dimensional (3D) biomaterials could elucidate collective dissemination during disease progre

60 ling approaches are seen as a way forward to elucidate complex biological regulatory mechanisms when

61 egant studies over the last two decades have elucidated complex molecular signaling governing the ide

62 Here, we report a data-driven approach to elucidate degradation trends of plastic debris by linkin

63 in yeast GAL metabolic regulation, but also elucidated design principles for ratio-sensing signal pr

64 idative stress both in vitro and in cells to elucidate details of the interactions between Fe(2+) and

65 quencing and CRISPR-Cas9 barcode editing for elucidating developmental lineages at the whole organism

66 ion, genetic modifier screens can be used to elucidate disease mechanisms and causal determinants of

67 rse populations identify additional loci and elucidate disease-associated genes, biology, and pathway

68 is two-stage hand-and-elbow gating mechanism elucidates distinct tissue-specific modulations, pharmac

69 ave been made over the past several years in elucidating drug-induced changes at molecular, cellular,

70 rophin gene locus, with the ultimate goal to elucidate dystrophin protein function and stability in s

71 ehold survey analysis, process modeling), we elucidate factors associated with user satisfaction and

72 ing in a model archaeon, Haloferax volcanii, elucidating, for the first time, the translational lands

73 Investigation of sulfur metabolism elucidates frequent cross-compartment exchange of a stan

74 ain's sensitivity to oxidative damage can be elucidated from the structural proteome, though future e

75 This tool is expected to help elucidate fundamental physiological and pathological pro

76 the advances enabled by these structures for elucidating fundamental biology as well as developing im

77 Future research should elucidate further the relative contribution of vision lo

78 ological advances enabled the field to begin elucidating gene regulation at the single-locus level.

79 igarette smoke toxin exposure; as well as to elucidate genes required for iron acquisition and a func

80 This work elucidates host genes that render microglial cells susce

81 We present a theoretical model to elucidate how a negative feedback mechanism, tied to the

82 is Article, we describe three experiments to elucidate how CysS uses Cbl, SAM, and a [4Fe-4S] cluster

83 We aimed to elucidate how habituated amounts of protein intake affec

84 Our studies help elucidate how HSV gE/gI and US9 promote the assembly of

85 n on fossil fuels, there is a strong need to elucidate how nitrogenase achieves this difficult reacti

86 This discovery paves the way to elucidate how polar Tfp machines are regulated to coordi

87 The aim for this study was to elucidate how the hypothalamic hunger-inducing hormone a

88 This elucidates how LiB performance is markedly affected by m

89 the efficiency of biological processes, and elucidating how chemical reactivity is efficiently contr

90 14q32 has enabled the use of mouse models to elucidate imprinting mechanisms and decipher the contrib

91 epidemiology of frailty remains to be fully elucidated in a real-world surgical population.

92 c and mitral valve replacements) was further elucidated in large-cohort outcome trials.

93 d neurovascular barrier maturation have been elucidated in recent years.

94 Our data elucidated intermediate states during antibiotic recogni

95 these ABO effects on VWF have not been fully elucidated, it seems likely that they are mediated in la

96 using convolutional neural network (CNN) to elucidate its clinical implication in oncological perspe

97 rmine the binding partners of CLC/Gal-10 and elucidate its role in eosinophil biology.

98 over, several efforts are also being made to elucidate its underlying mechanisms in therapeutic resis

99 ectral congestion, necessitating modeling to elucidate key spectral features.

100 ding our understanding of their function and elucidating key structural motifs that can be targeted f

101 The purpose of this study was to elucidate mechanisms by which PXN affects cancer growth

102 om a full repertoire of potential ones helps elucidate mechanisms of cancer development.

103 severity of nerve damage, and to potentially elucidate mechanisms of injury, thereby aiding the medic

104 lving armamentarium of treatment options, to elucidate mechanisms of resistance, and to continue the

105 by diverse risk variants for SCZ and ASD and elucidate mechanisms through which highly penetrant, mul

106 Protein design is a powerful tool for elucidating mechanisms of function and engineering new t

107 Elucidating mechanisms underlying susceptibility of host

108 efining protein-associated intermediates and elucidating mechanistic details of enzymatic processes.

109 context-specific metabolism is critical for elucidating metabolic drivers of larger phenotypes and d

110 e large downstream impacts on our ability to elucidate molecular drivers of disease-associated dysbio

111 this organism a suitable model organism for elucidating molecular mechanisms of copper transport and

112 We summarize recent work in elucidating molecular mechanisms that govern three-dimen

113 Our results elucidate neural mechanisms mediating the utility of age

114 terized longitudinal sample, which helped to elucidate neurobiological mechanisms involved in complex

115 routinely used for retrospective analysis to elucidate new biology.

116 rstanding of neuron-cancer interactions will elucidate new therapeutic strategies for these presently

117 ed scientific exploration, including further elucidating of the genetic pathway of which it is a part

118 Similar studies could help elucidate other DNA enzymes with activities coordinated

119 We discuss chemical tools that have enabled elucidating otherwise intractable biological processes b

120 Intensive efforts have focused on elucidating pancreatic transcriptional programs that can

121 usage and somatic hypermutation profiles, we elucidate physiological BCR repertoires in mouse PP GCs.

122 We elucidate prey (Antarctic silverfish[Pleuragramma antarc

123 nk-mediated inner-ear sensory perception and elucidate protocadherin-15's structural and adhesive pro

124 The elucidated quantitative relationship provides guidance t

125 To elucidate responses to early HIV-1 replication, we studi

126 l correlates of STBs and NSSI in youth to 1) elucidate shared and independent neural alternations, 2)

127 ata and the design of further experiments to elucidate signalling mechanisms within the core signalli

128 xperiments and molecular dynamics studies to elucidate slipping dynamics and conformations of (CAG)n

129 egulatory enzymes that drive the cell cycle, elucidated structural components that underly essential

130 (HDX-MS) of complexes I and II on membranes elucidated structural determinants that enable them to b

131 used experimental and modeling approaches to elucidate such impacts in flow-electrode capacitive deio

132 Theoretical calculations elucidate that the reaction free energy of HCOO* protona

133 studies in other primary sensory areas have elucidated that pyramidal and inhibitory neurons belongi

134 cyanobacterium Synechocystis sp. PCC6803 to elucidate the action of Ca(2+) and peripheral proteins.

135 Further research is needed to elucidate the appropriate indications for the prescripti

136 We used this database to elucidate the breakdown of embodied carbon emissions acr

137 sation (MR) analysis is an important tool to elucidate the causal relevance of environmental and biol

138 These results elucidate the cellular logic that underlies distinct thi

139 use of selected chemical transformations to elucidate the chemical nature of a radioactive contamina

140 Future research should elucidate the complex relationships between demographics

141 In order to better elucidate the complex role played by CYP2J2 in cardiac c

142 Our structure and systematic analysis elucidate the contributions of Hoogsten hydrogen bonds,

143 A useful simplification can elucidate the core dynamics of a system.

144 ultrafast transient absorption spectroscopy, elucidate the critical role of electron transfer (ET) fr

145 Additionally, our work begins to elucidate the critical role of isotype for an influenza

146 human HD and control fibroblasts and use to elucidate the CSF/brain and peripheral tissue expression

147 Despite numerous attempts to elucidate the developmental mechanisms responsible for t

148 Here, we discuss MGMT as a biomarker and elucidate the discordance between MGMT methylation, expr

149 st to map DNA damage formation and repair to elucidate the distribution of damage on a genome-wide sc

150 alysis of the PHI surface photoreactions, we elucidate the dominantly diffusiophoretic propulsion mec

151 ties with a predator exclusion experiment to elucidate the drivers, both geomorphic and biotic, contr

152 easurements and PARAFAC analysis was used to elucidate the dynamic changes in DOM composition/optical

153 Weighted mobility analysis can elucidate the electronic structure and scattering mechan

154 sing small angle X-ray scattering (SAXS), we elucidate the ensemble of Bvht RNA conformations in solu

155 We elucidate the evolution of the entrained air in drop imp

156 n-capture carbon-copy sequencing (5C-seq) to elucidate the extent to which long-range chromatin loops

157 Therefore, the objective of this study is to elucidate the extracellular matrix (ECM) structure, comp

158 In order to elucidate the factors that control the stereoselectivity

159 h varied protecting groups to systematically elucidate the factors that influence their reactivity to

160 In a recent paper, Ciudad et al. elucidate the first atomic structures of Abeta oligomers

161 g-namely, total-internal reflection (TIR)-we elucidate the freezing kinetics during the solidificatio

162 ty to develop more cell-potent inhibitors to elucidate the function of NTMTs in the future.

163 Future research efforts should elucidate the functional consequences of this redistribu

164 We sought to elucidate the functional impact of L6CT projections from

165 will help the biomedical research community elucidate the functions and mechanisms of APA events in

166 o improve the mapping resolution and further elucidate the genetic relationship of height and maturit

167 Overall, the results of this study help to elucidate the heterogeneity found in these neoplasms, wh

168 e Michaelis complex in silico and used it to elucidate the hydrolytic mechanism in a GH45, Cel45A fro

169 ecular pharmacology of CCR5 and help further elucidate the inhibitory mechanisms of a group of potent

170 transmission electron microscopy analysis to elucidate the interplay between fluid instability and cr

171 none, allowed us for the first time to fully elucidate the isomeric structures of the MW 212 OSs.

172 Continued investigations are needed to fully elucidate the landscape of germline genetic alterations

173 We further elucidate the likely metabolic pathway and CYP isoforms

174 ational retrospective study was conducted to elucidate the longitudinal clinical course of patients w

175 ecosystem in the Northeast Pacific can help elucidate the magnitude of assemblage shifts, and whethe

176 Here we elucidate the mechanism by which CXCR4 inhibition affect

177 ammatory cytokine-induced CEnC death, and to elucidate the mechanism by which this cytoprotection occ

178 Our results elucidate the mechanism of host translation inhibition b

179 These results elucidate the mechanism of TDMD and expand its inferred

180 To elucidate the mechanism(s) of RBC-MV-induced coagulation

181 th deficient or excessive PE biosynthesis to elucidate the mechanism.

182 ors during internode morphogenesis will help elucidate the mechanisms coordinating axial growth with

183 ardiac regeneration enhancer in zebrafish to elucidate the mechanisms governing spatiotemporal gene e

184 bitat modification of a community, to better elucidate the mechanisms of bacterial interactions.

185 to estimate HDV-HBsAg-host parameters and to elucidate the mode of action and efficacy of REP 2139-Ca

186 c approach using deep mutational scanning to elucidate the molecular basis and underlying functional

187 To elucidate the molecular determinants of SAM domain funct

188 The results of this study elucidate the molecular mechanism of the Ras mutant-medi

189 amycin complex1 (TORC1), was investigated to elucidate the molecular mechanisms of vitellogenesis reg

190 cancer systems biology is to use big data to elucidate the molecular networks by which cancer develop

191 These simulations elucidate the molecular-scale mechanisms of viral capsid

192 imensional STED has been extensively used to elucidate the nanoscale membrane structure and dynamics

193 inated (365 nm, 125 mW cm(-2)) conditions to elucidate the nature of this plasmonic enhancement.

194 as a genetically unaltered cellular model to elucidate the neurodevelopmental aspects of schizophreni

195 phasizes recent research efforts in order to elucidate the next steps needed to develop a fundamental

196 These findings elucidate the NOD2-mediated mechanism of cytoprotection

197 y measure clonal complexity, or definitively elucidate the order of mutations.

198 Herein, we applied genomic approaches to elucidate the origin of the scanning model and its under

199 Here we elucidate the origin of the switching mechanism in atomi

200 ein reconstruction and biophysical assays to elucidate the origins of vertebrate haemoglobin, a heter

201 ains are subject to intensive study and help elucidate the palaeoenvironment where these animals live

202 In this review, we elucidate the pathology of the BBB, its ability to poten

203 Here we formulate a theoretical framework to elucidate the phase behavior of the linker-mediated vitr

204 thways governing liver development will help elucidate the physiological and pathological processes i

205 Our findings elucidate the potential oncogenic function of intergenic

206 We elucidate the potential risks and opportunities to Egypt

207 These findings elucidate the potential utility of plasma SPM concentrat

208 To elucidate the precise role of iNKT cells in AD developme

209 Here, we elucidate the previously unknown molecular mechanism gov

210 Here, we elucidate the propagation of network activity from the h

211 These results could help elucidate the protumor mechanisms of iCAFs.

212 tudy, a comprehensive model was developed to elucidate the reaction mechanisms and simulate reaction

213 A computational framework was used to elucidate the reinforcement-learning mechanisms that cha

214 Future studies will further elucidate the role of DSIF in transcriptional dynamics a

215 s a regulator of innate immunity and further elucidate the role of HC.HA complexes in inflammation an

216 lactis consortia and mathematical models to elucidate the role of interaction variability in ecosyst

217 tissues, on SXR knockout mice (SXRKO) and to elucidate the role of SXR in PCB-153 metabolism and prom

218 To elucidate the role of the CR and determine why CR deleti

219 -HT) functioning, the current study aimed to elucidate the role of these neurotransmitters in the soc

220 solution views of giant larvacean houses and elucidate the role that house structure has in food capt

221 and vesicular content release, we sought to elucidate the signaling pathway downstream of PAR4 activ

222 We elucidate the significance of this new culture medium fo

223 We used two-photon microscopy to elucidate the spatial organization, motility characteris

224 We elucidate the spin properties which are highly sensitive

225 We elucidate the structural basis for differential binding

226 studies by cryo-EM, but also pave the way to elucidate the structural basis of amyloid strains and to

227 These models provide a platform to elucidate the structural basis of RAF activation by RAS

228 n, single-crystal X-ray analysis was used to elucidate the structural features of the macrocycles.

229 Here we used cryo-electron microscopy to elucidate the structure of an agonist-bound activated DR

230 of these aggregates has made it difficult to elucidate the structure-property relationships.

231 The results allow to elucidate the structures and bonding in the two clusters

232 ater conditions, providing an opportunity to elucidate the underlying dynamical processes.

233 esent 2 new animal models that will serve to elucidate the underlying mechanisms further.

234 rovides a robust criterion to experimentally elucidate the underpinnings of both actomyosin activity

235 nsient interactions between AcpP and FabD to elucidate the X-ray crystal structure of a type II ACP-A

236 The purpose of this study is to elucidate the yield of diagnostic evaluation including m

237 Current studies have elucidated the functions of histone acetylation in the m

238 We elucidated the influence of organotin cations and ammoni

239 Here, we elucidated the mechanistic role of an intrinsically diso

240 Taken together, our results elucidated the molecular mechanism of indole-induced ant

241 Field-emission scanning electron microscopy elucidated the morphology of the subpopulations, and 20

242 Moreover, we elucidated the neuronal mechanism of RLN3/RXFP3 signalin

243 We elucidated the organization and activity of this TRN by

244 In addition, we elucidated the paralogous gene history for the mammalian

245 Using NMR spectroscopy, we have elucidated the solution-phase structure of apo-BlLPMO10A

246 , longitudinal assessment of pathogen burden elucidated the temporal sequence of events associated wi

247 It also elucidates the critical variables for the development of

248 recent ultrafast dynamics in flavodoxin and elucidates the fundamental mechanism of nonequilibrium E

249 This elucidates the general film formation mechanism of 2D ha

250 Our study elucidates the genetics of gene expression in neonatal i

251 Our study elucidates the mechanism by which meiotic cells modulate

252 Collectively, this report elucidates the mechanisms of hepatic uptake of androgen

253 e formation of a wide range of mudstones and elucidates the origins of variability in the global stab

254 This study elucidates the population dynamics and diversification o

255 with functional characterization, this work elucidates the previously unknown architecture of pannex

256 g HPV16 E6 and E7, have been instrumental in elucidating the activities of cellular signaling network

257 nces in the identification of intermediates, elucidating the catalytic mechanism of this multi-redox

258 Cell ablation is a powerful method for elucidating the contributions of individual cell populat

259 ssues in the survey confirms our hypotheses, elucidating the cultural cognition or rationality that u

260 mprised of many interacting traits, and that elucidating the genetic basis of these traits is require

261 By elucidating the HCV interactome, we identified the 17-be

262 lectrooxidation of PFASs in water, aiming at elucidating the impact of different operational and desi

263 Elucidating the influence of the monolayer interface ver

264 Elucidating the interplay among the DNA damage response

265 n this Review, we discuss recent advances in elucidating the mechanisms by which BRCA1-BARD1 function

266 Elucidating the mechanisms by which CHIKV subverts antiv

267 Elucidating the mechanisms by which HCMV stimulates mono

268 Elucidating the mechanisms of these interactions is an i

269 Elucidating the mechanisms that sustain asthmatic inflam

270 These findings contribute to elucidating the mechanisms that underlie the male bias i

271 Further elucidating the mechanisms through which NHERF1 modulate

272 exual dimorphism evolves would contribute to elucidating the mechanisms underlying the diversificatio

273 lerene acceptors (NFAs) is very critical for elucidating the origin of their extraordinary charge gen

274 Predicting, controlling, understanding, and elucidating the phase transition from gel to crystal are

275 derlying metabolic networks is essential for elucidating the physiological and ecological significanc

276 Fortuitously, there is increased interest in elucidating the physiological roles of SLCs as well as g

277 two-fold: (i) to inspire readers by further elucidating the properties and functionalities of existi

278 approach establishes a framework for further elucidating the relationship between the structures of p

279 oviding the basis for further investigations elucidating the role of dedicated AMPK subunits in the m

280 The next step in elucidating the role of these agents is to determine the

281 and INS), and ab initio simulations aimed at elucidating the synthesis-property relationships in Na(3

282 lytic synthesis are discussed, with focus on elucidating the underlying performance descriptors that

283 To elucidate their catalytic cycle and inhibitory mechanism

284 ed ionizable residues comprehensively and to elucidate their effect on the conformational transition.

285 of conserved structural RNAs is important to elucidate their function and mechanism of action.

286 ved with the different oxidation pathways to elucidate their mechanistic differences.

287 To elucidate their properties, solvent and substitution eff

288 By elucidating their ability to utilize NCT, these findings

289 rapeutic effects of these treatments help to elucidate therapeutic or pathological mechanisms, and to

290 To elucidate these processes, a variety of experimental app

291 Elucidating this cryptic Se cycle is essential for under

292 However, elucidating this influence experimentally is difficult b

293 echanisms, as well as their applications are elucidated to create a backdrop for future research.

294 tumor volume for overall survival are poorly elucidated to date.

295 The aim of this study was to elucidate various molecular mechanisms involved in diffe

296 Here we elucidate when, where, and how the earliest sustained se

297 This study aimed to elucidate whether N1 could modulate microglial function

298 Further research is needed to elucidate whether upregulation of ACE2 expression in air

299 Specifically, it remains to be elucidated whether changes in frequency only modulate se

300 substrate binding and catalysis and clearly elucidate why previous structures of mammalian dCTPase w