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1 different levels along the body axis of the embryo.
2 ols body axis morphogenesis in the zebrafish embryo.
3 vertebrates, is the rejection of the nonself-embryo.
4 arge-scale mechanics in a rapidly developing embryo.
5 tionally overlap cell states observed in the embryo.
6 determines the posterior pole of the future embryo.
7 at uses temperature to direct the sex of the embryo.
8 d limb skeleton in the developing vertebrate embryo.
9 the regulative nature of the early mammalian embryo.
10 subset of mesodermal markers in the Xenopus embryo.
11 pancreatic bud of a Carnegie stage 14 human embryo.
12 cifying the first trophectoderm cells of the embryo.
13 plan while extraembryonic layers sustain the embryo.
14 ecially in complex systems such as the mouse embryo.
15 inherited fate determinants in the mammalian embryo.
16 and transfer of developmental control to the embryo.
17 osperm supplies pyridoxine to the developing embryo.
18 es of specialized cells when restored to the embryo.
19 nuclear translocation of NRDE-3 in the early embryo.
20 primary decidual zone (PDZ) surrounding the embryo.
21 at the sink end, its import into the growing embryo.
22 logy measurements in Drosophila melanogaster embryos.
23 al stages at similar timings as conventional embryos.
24 uch a protein (AfrLEA6) in its anhydrobiotic embryos.
25 nd abnormal craniofacial morphology in later embryos.
26 cing on zebrafish, chicken, mouse, and human embryos.
27 that were in turn enhanced in Lgp2 deficient embryos.
28 can be used in medaka, killifish, and mouse embryos.
29 nalysis of fully intact and living zebrafish embryos.
30 stitutive and striatal-specific Nolz1 mutant embryos.
31 e enriched in nascent myotubes in Drosophila embryos.
32 nts that drive cellularization in Drosophila embryos.
33 ild-type, but not in Rig-I or Mda5 deficient embryos.
34 ze candidate genes for HRV in live zebrafish embryos.
35 cy AFFF sample and its toxicity in zebrafish embryos.
36 plete specific mRNA transcripts in zebrafish embryos.
37 skeletal muscle signature in etv2-deficient embryos.
38 nts and M-lines in slow fibers of the mutant embryos.
39 of the epidermal layer in developing Xenopus embryos.
40 ith N6-methyl-dATP compared with noninjected embryos.
41 al organoids and cell distributions in mouse embryos.
42 osition prefigure these disruptions in LgDel embryos.
43 e in Delta-like 4 (Dll4) knockdown zebrafish embryos.
44 of individual blastomeres of mouse and human embryos.
45 ion regulation in germ lines and early stage embryos.
46 ciency enhanced, HSPC emergence in zebrafish embryos.
47 ced OF hyaloid vascularization in pax2a(-/-) embryos.
48 he development of the body axis in zebrafish embryos.
49 the yolk sac and immature microglia in early embryos.
50 ng of the wound response in living zebrafish embryos.
51 dorsal-ventral axis patterning of Drosophila embryos.
52 pment, and biological functions of zebrafish embryos.
53 tended to other animal models, using chicken embryos.
54 cynomolgus macaques to generate in vitro MCM embryos.
55 formation extracted from unlabeled zebrafish embryos.
56 pment in wild-type and etv2 mutant zebrafish embryos.
57 61 transcription factors in ethanol-exposed embryos.
59 indle [1], is notably large in the zebrafish embryo (246.44 +/- 11.93 mum(2) in a 126.86 +/- 0.35 mum
61 ational changes in Zelda-depleted Drosophila embryos; (3) patient-specific aberrant chromatin conform
62 mum diameter cell) compared to a C. elegans embryo (5.78 +/- 0.18 mum(2) in a 55.83 +/- 1.04 mum dia
63 TADs) in gametes and their appearance in the embryo(8,9) versus the pre-existence of TADs and loops i
64 ll RNA-seq to the 16-cell stage of the Ciona embryo, a marine chordate and performed a computational
65 eling of single CN V axons in LgDel+/- mouse embryos, a genomically accurate 22q11.2DS model, and 3D
68 gammaC4 is expressed at higher levels in the embryo and earlier postnatal weeks, it is also expressed
69 ionship between the yolk sac and the primate embryo and highlight the pivotal role of the yolk sac as
70 of pregnancy in a postimplantation mammalian embryo and indicate that impairment of the Hippo signali
71 late the biophysical properties of the early embryo and mediate the self-organization of "gastrulatio
72 ngiogenic sprouting of ECs in the developing embryo and provide pharmacological evidence for a role o
74 he neural crest migrate along the developing embryo and traverse the dermis to reach the epidermis, c
76 relate with increased cell mobility in early embryos and abnormal craniofacial morphology in later em
77 t in the epaxial region of the double mutant embryos and are able to divide and contribute to muscle
78 rtments A/B are markedly weak in 1-cell SCNT embryos and become increasingly strengthened afterward.
82 aling is partially active in Nodal-deficient embryos and its inhibition exacerbates their C and E def
85 elanoma-derived cells into G2 tert zebrafish embryos and observed that tissue environment with short
88 easure heat dissipation by living zebra-fish embryos and to estimate the energetics of specific devel
89 dorsal-ventral axis of the early Drosophila embryo, and we found that an empirical description of th
92 en compared with non-sauropod sauropodomorph embryos, and demonstrates that the specialized craniofac
94 se (PI3K)/AKT/mTOR signalling in early human embryos, and in both primed and naive pluripotent cultur
96 e from which cell layers in contact with the embryo are regularly eliminated and to which additional
98 y estimate that the Massospondylus carinatus embryos are only approximately 60% through their incubat
99 ipe 2 of the even-skipped gene in Drosophila embryos as a case study, we dissect the regulatory force
100 xpression remains reproducible even when the embryo aspect ratio is artificially reduced by more than
101 beating atria in 381 live, intact zebrafish embryos at 2 and 5 days post-fertilization highlighted g
104 h positive correlation between the cell- and embryo-based test systems emphasizes the appropriate mod
105 nt of post-implantation development of human embryos bearing common aneuploidies using a recently est
106 dant mutant phenotypes in both endosperm and embryo because the two sperms that participate in double
108 or the development of pre-implantation mouse embryos, but the mechanism accounting for such a require
109 te zygotic transcription in Drosophila early embryos, but whether other factors support this dynamic
110 MP gradient is interpreted in the Drosophila embryo by combining live imaging with computational mode
111 Global mapping of STRAP-RNA binding in mouse embryos by enhanced-CLIP sequencing (eCLIP-seq) reveals
112 l transfer protein (alpha-TTP)] in zebrafish embryos causes death within 24 h post-fertilization (hpf
113 rnal anemia but still adversely affected the embryo, causing anemia, tissue iron deficiency (includin
115 alary cell behaviors in wild-type and mutant embryos, comparison of temporal dynamics in contracting
116 roporation of shRNAs in H. symbiolongicarpus embryos constitutes an important experimental resource f
117 tilization in vitro (IVF), but the available embryo culture medium in the current method is only a fe
118 ble detection of the growth factor from each embryo culture medium of such a small concentration henc
120 f all six TIR1/AFB proteins results in early embryo defects and eventually seed abortion, and yet a s
121 n be further increased by electroporation of embryos derived from Cas9-expressing donor females.
127 emale carries the same symbiont strain, then embryos develop properly, thereby imparting a relative f
128 we report that LEC-specific Reln-null mouse embryos develop smaller hearts, that RELN is required fo
129 ated by increased N6-methyl-dA DNA levels in embryos developed from MTH1 knock-out zebrafish eggs mic
130 morphology, to identify the condition of an embryo development after fertilization in vitro (IVF), b
131 tes that TEs are highly transcribed in early embryo development and contribute to distinct biological
132 ey findings on the roles of SAGA and ATAC in embryo development and in cancer to better understand th
135 e formation of sulfonated amino acids during embryo development in the egg at no cost of reduced sulf
137 ytes are released and fertilized, subsequent embryo development is retarded, and the embryos potentia
138 /-) seeds were nonviable, displayed aberrant embryo development, and had >80% reduced oil content ver
139 erase-like protein Dnmt3l, which, during the embryo development, cooperates with Dnmt3a and Dnmt3b to
140 f maternally deposited DOT1L is required for embryo development, we carried out a conditional Dot1l k
142 uble mutant combinations reported to disrupt embryo development; emphasize the importance of followin
143 utionarily conserved, the speed at which the embryo develops can vary substantially between species.
154 1 mutations were normal, double heterozygous embryos exhibited an incompletely penetrant syndrome of
155 p2a hyperactivity, where kctd15a/b-deficient embryos exhibited increased abundance of this transcript
160 egrin alpha5 proteins in K41 wild-type mouse embryo fibroblasts (MEFs), CRT null MEFs were unresponsi
162 virus Ankara (CVA) vaccine strain in chicken embryo fibroblasts during which numerous mutations and d
168 to litter after embryo transfer compared to embryos from males with low DFI (20.4 +/- 7.9% for IVF a
173 ld to severe, but generally betaA-Akt1WT/flx embryos had fewer visible blood vessels and more hemorrh
174 ead mosaic aneuploidies, with 59 of 74 (80%) embryos harboring at least one putative aneuploid cell (
175 t elevating Dishevelled levels in Drosophila embryos has paradoxical effects, promoting the ability o
176 mice at E9.5 and E10.5 showed that Fkbp8-/- embryos have an abnormal expression profile within tissu
177 Our analysis revealed that prdm8 mutant embryos have fewer motor neurons resulting from a premat
181 eq to carry out a study of expression in (i) embryos; (ii) ovaries from partially and fully engorged
184 e show that Wnt3a is expressed in the caudal embryo in a dorsal-ventral (DV) gradient across all thre
187 tissue assigns the fate of each cell in the embryo in order for a uniform field of cells to differen
188 AFFF toxicity was assessed in zebrafish embryos in comparison with four major constituents: perf
190 ns and orientations in the epiblast of chick embryos in the early stages of primitive streak formatio
191 izing the biomolecular distribution of whole embryos in three dimensions, (ii) resolving anatomical f
192 in oocytes, sperm and early preimplantation embryos, including atypical patterns of histone modifica
193 esis was coordinately downregulated in these embryos, including the most downregulated gene nsdhl.
194 conclusion, the electrofusion of rabbit SCNT embryos induced oxidative stress, disturbed the epigenet
195 dition, the level of mosaicism was higher in embryos injected with Cas9 mRNA (100%) compared to those
196 (genome-wide off-target analysis by two-cell embryo injection) to detect off-target mutations by edit
198 sential maternal hepcidin suppression is for embryo iron homeostasis, we mimicked the range of matern
199 of cells in the mesoderm layer of the early embryo is essential for organization of the body plan.
200 mother, suggesting that the integrity of the embryo is monitored by the vulva to detect damage and in
203 required for BMP-mediated patterning of the embryo, is dispensable for both ligand-independent signa
206 ent of IVF and CCR5 editing protocols in MCM embryos lays a foundation for the creation of CCR5-mutan
207 tial for survival, null mutations often have embryo lethal phenotypes that prevent elucidation of sub
208 among the three mtACPs was indicated by the embryo-lethal phenotype associated with simultaneous los
209 its molecular functions, we transformed the embryo-lethal tps1-1 null mutant with various forms of T
211 eficiency or malformations, the incidence of embryo loss and malformations was significantly higher,
213 Mycobacterium marinum strains in a zebrafish embryo model of tuberculosis and (iv) in vivo temporal m
215 al programs during seed development, such as embryo morphogenesis, photosynthesis, and seed maturatio
216 active non-invasive approach, apart from the embryo morphology, to identify the condition of an embry
219 placing the equivalent of 10 glass slides of embryos mounted manually, our microfluidic approach grea
221 stinguish the development conditions of each embryo, not merely from an observation of embryo morphol
223 t hippocampal neuronal cultures derived from embryos of unknown sex, whether BDNF-induced signaling c
224 amniotic cavity immediately surrounding the embryo on embryonic day 13-13.5 (E13-13.5) corrected pre
226 probes can be imaged in developing zebrafish embryos over seven days with toxicity similar to injecte
227 n 2200 emb mutants and 241 pigment-defective embryo (pde) mutants analyzed in my laboratory; provide
229 ibit divergent mechanisms of toxicity in the embryo-placenta unit, whereas PFOA- and GenX-exposed liv
231 omosome segregation, inferring that 55 (74%) embryos possessed mitotic aneuploidies and 23 (31%) embr
232 uent embryo development is retarded, and the embryos potentially fail to thrive due to lack of luteal
233 w that females ovulate, mate, and form a new embryo prepartum while still carrying a full-term fetus
234 ors revealed that morphologically non-viable embryos produce higher levels of IL-8 and TNFalpha, asso
235 tivating enzyme), and increased IAA in their embryo, produced longer seedling shoots and roots, than
237 rade-off between immunological tolerance and embryo rejection accompanied the evolution of unique mal
238 incidence and impacts of mosaicism in human embryos remain controversial, with most previous studies
243 tee this robustness and which anticipates an embryo's response to perturbations in lineage compositio
246 sment of cell proliferation across zebrafish embryo segmentation, using the FUCCI transgenic cell-cyc
249 servations, and the ability to image several embryos simultaneously, support the use of eZXM and SPIM
252 al anomalies in a proportion of heterozygous embryos, suggestive of a dominant mode of inheritance.
261 l epigenetic information transmission to the embryo through the homogeneous retention of methylated h
264 ransition and migrate through the developing embryo to give rise to portions of the outflow tract, th
266 ated Langendorff technique using the chicken embryo to study the physiology of the developing heart.
267 ombinations of steroid mixtures in zebrafish embryos to assess their joint activities on physiology a
268 ome editing reagents into single-cell bovine embryos to compare the effect of Cas9 mRNA and protein o
270 mental hindbrain nuclei neurons in zebrafish embryos together with subcellular imaging, optogenetics,
271 .3 +/- 8.1% for ICSI) failed to litter after embryo transfer compared to embryos from males with low
275 reover, we show that diploid cells in mosaic embryos undertake compensatory proliferation during the
279 chia coli (E. coli) and transgenic zebrafish embryos, we are able to design optimized antibacterial s
280 mutants and NKX2-1 ChIP-sequencing in mouse embryos, we delineate the NKX2-1 transcriptional program
281 of small RNAs from Bactrocera dorsalis early embryos, we identified an autosomal-derived microRNA, mi
285 er than expected numbers of betaA-Akt1WT/flx embryos were seen beginning at E11.5, but a few survived
287 time-resolved ChIP-seq assays in Drosophila embryos were used to dissect the ERK-dependent control o
288 we observed toxicity in early Xenopus laevis embryos when using such a conventional optogenetic desig
289 This system also operates in mouse and human embryos, where EPHA receptors are enriched in pluripoten
290 ent in both wild-type and snail twist mutant embryos, where our theoretical prediction is further imp
291 the cardiovascular system in the developing embryo, which are independent of effects on the mother a
292 is enhanced in Med23(fx/fx);Wnt1-Cre mutant embryos, which, together with downregulation of Col2a1 a
294 s during embryogenesis, we treated zebrafish embryos with ethanol during pre-gastrulation period and
295 SCs transiently expressing Gata4 endows iETX embryos with greater developmental potential, thus enabl
298 e first cell cycle in the zygote, leading to embryos with non-mosaic restoration of the reading frame
300 sed levels of 7-DHC in all organs of exposed embryos, with a particularly strong effect in the brain.