ライフサイエンスコーパス: embryoid

1 ), and differentiated cells via formation of embryoid bodies (16, 20 days) were analyzed.

2 e cell suspensions obtained from day 7 human embryoid bodies (d7EBs) injected i.v. 1 hour after cecal

3 s study, using ESC derived aggregates called embryoid bodies (EB) as a model, we characterized the bi

4 yonic stem (ES) cells were differentiated as embryoid bodies (EBs) and assayed for blast colony-formi

5 bstrates generate size- and shape-controlled embryoid bodies (EBs) and can be easily modified to cont

6 mically defined medium supports formation of embryoid bodies (EBs) and differentiation of hepatic lin

7 We found that ERbeta was induced in embryoid bodies (EBs) and neural precursor cells (NPCs)

8 (VE-cadherin)-expressing cells generated in embryoid bodies (EBs) and on OP9 cells.

9 iation, as seen in poorly differentiated TKO embryoid bodies (EBs) and teratomas.

10 at hTERT silencing during differentiation to embryoid bodies (EBs) and to fibroblast-like cells was d

11 , we used embryonic stem cell-differentiated embryoid bodies (EBs) as a model and found that Bnip3 (B

12 dy we used mouse embryonic stem cell-derived embryoid bodies (EBs) as a model for peri-implantation d

13 S) cells can differentiate in vitro, forming embryoid bodies (EBs) composed of derivatives of all thr

14 Embryoid bodies (EBs) derived from cells lacking the aut

15 e stages of ExEn differentiation in cultured embryoid bodies (EBs) derived from either embryonic stem

16 Compared to wildtype (WT) controls, embryoid bodies (EBs) derived from either Lefty or Cerb-

17 Measuring the Shh response in neuralized embryoid bodies (EBs) derived from embryonic stem (ES) c

18 n, calponin, and LPP, were down-regulated in embryoid bodies (EBs) derived from embryonic stem cells

19 Here we demonstrate that embryoid bodies (EBs) differentiated from talin1-null em

20 cadherin positive cells developed within the embryoid bodies (EBs) formed by differentiating ES cells

21 ut embryonic stem cells (VIM -/- ESCs) using embryoid bodies (EBs) formed from both cell types.

22 Embryoid bodies (EBs) generated from embryonic stem cell

23 Wnt2(-/-) embryoid bodies (EBs) generated increased numbers of Flk

24 te into cell types of all germ layers within embryoid bodies (EBs) in a highly variable manner.

25 endoderm following their differentiation to embryoid bodies (EBs) in culture.

26 describe the internal organization of murine embryoid bodies (EBs) in terms of the structures and cel

27 tiating ES cells into cardiomyocyte-positive embryoid bodies (EBs) in vitro.

28 Rac1 ablation in embryonic stem cell-derived embryoid bodies (EBs) leads to massive apoptosis of epib

29 arge numbers of homogeneous and synchronized embryoid bodies (EBs) of defined sizes from dissociated

30 lls was dramatically delayed and impaired in embryoid bodies (EBs) of Shp-2 mutant origin.

31 c stem (ES) cells as they differentiate into embryoid bodies (EBs) or into extraembryonic endodermal

32 Here, we differentiated mouse iPSCs into embryoid bodies (EBs) or representative cell types spann

33 Expression of RUNX1a in embryoid bodies (EBs) promotes definitive hematopoiesis

34 ere are numerous AS events observed in mouse embryoid bodies (EBs) undergoing a neuroectoderm-like st

35 h endogenous nuclear huntingtin in wild-type embryoid bodies (EBs) was associated with PRC2 subunits

36 oximately 65%) of cocultured ES cell-derived embryoid bodies (EBs) were enriched in cardiac myocytes

37 l patterning signals, murine ES cell-derived embryoid bodies (EBs) were grafted into avian hosts.

38 m and abnormal PPAR-gamma pathway in beating embryoid bodies (EBs) with defined media, we established

39 peptide to the media enhanced the growth of embryoid bodies (EBs), increased the expression of hemat

40 Upon ES cell differentiation into embryoid bodies (EBs), we observed a shift in expression

41 In vitro, ES cells aggregate to form embryoid bodies (EBs), which differentiate into multiple

42 rmation of multicellular aggregates known as embryoid bodies (EBs), yet cell fate specification withi

43 affected by the size of ES cell colonies and embryoid bodies (EBs).

44 enerated in embryonic stem (ES) cell-derived embryoid bodies (EBs).

45 ions of hES-CMs in spontaneously contracting embryoid bodies (EBs).

46 arliest surface marker missing from SCL(-/-) embryoid bodies (EBs).

47 elopment in embryonic stem (ES) cell-derived embryoid bodies (EBs).

48 Using our 3D human embryoid bodies (hEBs) formation technology, we interlac

49 nd definitive erythromyelopoiesis from human embryoid bodies (hEBs) in serum-free clonogenic assays.

50 , we generated genetically mosaic neuralized embryoid bodies (nEBs) from mouse embryonic stem cells (

51 ricle with 40 to 75 rhythmically contracting embryoid bodies (totaling 1.3-2x10(6) cells).

52 ditions and the avoidance of feeder cells or embryoid bodies allowed synchronous and reproducible dif

53 apoptosis-dependent process of cavitation in embryoid bodies and apoptosis associated with embryonic

54 tro differentiation potentials of iPSCs into embryoid bodies and different hematopoietic cell types.

55 Pten-/- ES cells formed aberrant embryoid bodies and displayed an altered ability to diff

56 how that Bmp2 and Bmp4 are expressed in PSA1 embryoid bodies and embryos at the stages when visceral

57 Upon differentiation into embryoid bodies and further into mineral-producing osteo

58 on of flk1(+) angioblasts in differentiating embryoid bodies and increased the number of PECAM (plate

59 is repressed as ES cells differentiate into embryoid bodies and is undetectable in adult mouse organ

60 rs while increasing the numbers of secondary embryoid bodies and mixed hematopoietic colonies obtaine

61 Although embryoid bodies and organoids can exhibit some spatial o

62 o the NA extract enhanced differentiation of embryoid bodies and resulted in the early appearance of

63 haracterized by vigorous beating activity of embryoid bodies and robust expression of cardiac Mef2c,

64 em cell markers; have the capability to form embryoid bodies and teratomas, and can differentiate int

65 naling assay; 3) Pofut1(-/-) and Pofut1(+/+) embryoid bodies are indistinguishable in their ability t

66 cells before and during differentiation into embryoid bodies as well as various types of normal and t

67 mouse ES cells and that FAK signaling within embryoid bodies can direct stem cell lineage commitment.

68 Immunohistochemical analysis of embryoid bodies collected from these cultures revealed a

69 tiate in vitro into cystic structures called embryoid bodies consisting of tissue lineages typical of

70 Embryonic stem cell-derived embryoid bodies contain a unique precursor population wh

71 Nodal-expressing hESCs developing as embryoid bodies contained an outer layer of visceral end

72 A study using embryoid bodies demonstrated a nonimmediate role played

73 Embryoid bodies derived from embryonic stem cells recapi

74 s also different from the null phenotype, as embryoid bodies derived from ES cells in which endogenou

75 Differentiated embryoid bodies derived from GATA6(-/-) ES cells lack a

76 ind that hematopoietic CD34(+) cells in spin embryoid bodies derived from human embryonic stem cells

77 We demonstrate that embryoid bodies derived from KLF2(-)(/)(-) ES cells can

78 In this study, we used differentiating embryoid bodies derived from mouse embryonic stem cells

79 The embryoid bodies derived from mutant cells are also unabl

80 Embryoid bodies derived from these cell lines are unable

81 and impaired primitive ectoderm formation in embryoid bodies differentiated from mouse embryonic stem

82 zyme activity occurring at later stages when embryoid bodies differentiated toward cardiomyocytes.

83 Levels of Neu5Gc on HESC and embryoid bodies dropped after culture in heat-inactivate

84 Pharmacological responses of beating embryoid bodies exposed to a comprehensive panel of drug

85 Flk-1(+) Tet-notch4 cells from d 3 embryoid bodies exposed to doxycycline (Dox(+)) were com

86 with retinoic acid, the majority of cells in embryoid bodies expressed markers for neural progenitors

87 -1alpha/ARNT heterodimers) because Arnt(-/-) embryoid bodies fail to exhibit hypoxia-mediated progeni

88 nd growth factors by ESCs differentiating as embryoid bodies for up to 14 days was assessed using PCR

89 Differentiating embryoid bodies form blood islands, providing an in vitr

90 roarrays to identify targets of Brachyury in embryoid bodies formed from differentiating mouse ES cel

91 lar criteria in the outer PE-like lineage of embryoid bodies formed from embryonic stem cell lines ge

92 S) cells made extensive skeletal muscle, but embryoid bodies from myogenin (-/-) ES cells had greatly

93 oderm, which are prominent features of early embryoid bodies from normal ES cells.

94 Differentiated embryoid bodies from wild-type embryonic stem (ES) cells

95 ree media, human embryonic-stem-cell-derived embryoid bodies generate a KDR(low)/C-KIT(CD117)(neg) po

96 C development, spontaneously differentiating embryoid bodies give rise to CD105(+)CD90(+)CD73(+)CD31(

97 imitive endoderm cells of the outer layer of embryoid bodies gradually polarise, and formation of a p

98 irst appeared in embryonic stem cell-derived embryoid bodies grown for 7 days (7d).

99 Moreover, A(-)/A(-) embryoid bodies grown in suspension culture constantly s

100 ent development of keratinocytes from single embryoid bodies in cell culture.

101 re functionally abnormal; they yielded small embryoid bodies in in vitro differentiation experiments

102 Cells cultured in HESCO readily form embryoid bodies in tissue culture and teratomas in mice.

103 AdiPS cells also generate embryoid bodies in vitro and teratomas in vivo.

104 The resulting iPSCs formed embryoid bodies in vitro and teratomas in vivo.

105 cardiac differentiation was recapitulated in embryoid bodies in vitro.

106 n by HNF-3alpha and HNF-3beta was studied in embryoid bodies in which one or both HNF-3alpha or HNF-3

107 at addition of BMP protein to cultures of S2 embryoid bodies induces expression of Hnf4 and other vis

108 levels of unbound histones, and formation of embryoid bodies is accelerated.

109 dent differentiation of endothelial cells in embryoid bodies is also antagonized by BMPER.

110 system, we found that induction of VEGFR1 in embryoid bodies is also associated with ETS1 and HIF-2al

111 Studies of morphogenesis in embryoid bodies led to the current belief that it is pro

112 nd MyoD to support muscle differentiation in embryoid bodies made from myogenin (-/-) ES cells.

113 Like ES cells, embryoid bodies maintained constitutive Src and Fyn kina

114 Both HESC and derived embryoid bodies metabolically incorporate substantial am

115 patic differentiation protocol starting from embryoid bodies of hiPSCs (hiPSC-EBs) for robust mass pr

116 up to 200 microm within 1 day of plating P19 embryoid bodies on laminin-1 (EHS laminin).

117 (LIF) and could initiate differentiation in embryoid bodies or chimeric embryos, but failed to commi

118 tides (DR1, DR2, DR5), we show that in mouse embryoid bodies or F9 embryonal carcinoma cells, RARs oc

119 Whether formed from embryoid bodies or in nodules, hES-derived keratinocytes

120 differentiated cells, methods that generate embryoid bodies or organoids do not yield consistent and

121 re, which does not require the generation of embryoid bodies or prospective cell isolation, entails f

122 actor-beta treatment of isolated N629D/N629D embryoid bodies partially rescued this phenotype.

123 In particular, embryoid bodies produced from these Pgk-Pem ES cells do

124 4+ cells during ES cell differentiation from embryoid bodies provides an excellent model system and m

125 ction of mMix in embryonic stem cell-derived embryoid bodies results in the early activation of mesod

126 ne embryonic stem cells converted to beating embryoid bodies showed that only the proximal active reg

127 mbryos and mouse embryonic stem cell-derived embryoid bodies substantially decrease the emergence of

128 differentiation of mouse embryos and ES cell embryoid bodies suggest that aspects of early mammalian

129 these cells were induced to differentiate as embryoid bodies suggested that quite a few of the downre

130 We show that embryoid bodies support maturation of the primordial ger

131 Because embryoid bodies sustain blood development, we reasoned t

132 Embryoid bodies that are cultured in the presence of nep

133 hibitory factor, mouse ES cells give rise to embryoid bodies that can differentiate into mesoderm.

134 e previously used two cell lines, which form embryoid bodies that do (PSA1) or do not (S2) cavitate,

135 When aggregated into embryoid bodies they develop disorganised masses of diff

136 that (a) laminin enables beta1-integrin-null embryoid bodies to assemble basement membrane and achiev

137 Finally, exposure of stem cell-derived human embryoid bodies to hsa-miR-1294 mimic or antagomir oligo

138 anging drop embryoid bodies, and adhesion of embryoid bodies to surfaces at or before that day strong

139 We exposed stem cell-derived human embryoid bodies to the microRNA mimic or antagomir oligo

140 IF-deficient cells and enabled AIF-deficient embryoid bodies to undergo cavitation, a process of prog

141 ctopic beats were observed in 33% and 40% of embryoid bodies treated with sotalol and quinidine, resp

142 Differentiation of ES cells to embryoid bodies was associated with rapid transcriptiona

143 a dominant negative FAK, cell migration from embryoid bodies was inhibited, whereas alpha-myosin heav

144 n of this pathway in the primitive endoderm, embryoid bodies were cultured in the presence of a small

145 METHODS AND Embryoid bodies were derived from human keratinocytes, t

146 mRNA levels induced upon differentiation to embryoid bodies were down-regulated in homozygous null H

147 suppress cardiogenesis through Src kinases, embryoid bodies were exposed to the small molecule PP2,

148 organogenesis protocol was optimised whereby embryoid bodies were formed and patterned towards an eye

149 The outer cells of these embryoid bodies were found to gradually acquire the hall

150 e cloning efficiency and the ability to form embryoid bodies were restored in embryonic stem cells, i

151 ment membrane assembly was also evaluated in embryoid bodies where it was found that both LG1-3 and L

152 hat defined differentiation of ES cells into embryoid bodies with Activin-A and selection for T expre

153 Early treatment of NFATc1-DTR mouse embryoid bodies with diphtheria toxin efficiently ablate

154 They produce embryoid bodies with elevated levels of the primitive en

155 accomplished by reconstitution of PTEN-null embryoid bodies with PTEN mutants that lack only PTEN's

156 Incubation of embryoid bodies with the vital dye, Dil, revealed the pe

157 during differentiation of ES cells in vitro (embryoid bodies) and in vivo (teratomas).

158 l cultures are thought to self-organize into embryoid bodies, able to undergo symmetry-breaking, germ

159 lpha5-null ES cells were differentiated into embryoid bodies, although they were delayed in growth an

160 ere first expressed at day 4 in hanging drop embryoid bodies, and adhesion of embryoid bodies to surf

161 re differentiated into cardiomyocytes within embryoid bodies, and contracting cells expressing myocar

162 Here we isolate primordial germ cells from embryoid bodies, and derive continuously growing lines o

163 d spontaneous differentiation in cultures of embryoid bodies, and each of these steps involves signif

164 ized with flk1 expression in differentiating embryoid bodies, and HoxB5 potently transactivated the f

165 e hematopoietic stem cell differentiation in embryoid bodies, and large embryonic stem cell (ES)-deri

166 gocytosis were detected in PU.1(Spi-B/Spi-B) embryoid bodies, and myeloid colonies were present in he

167 progenitor cells present in differentiating embryoid bodies, and that these correspond to erythro-my

168 xpansion of the ESC population and growth of embryoid bodies, but release from the drug after an init

169 mesodermal lineages do not form in Wt1-null embryoid bodies, but this effect is rescued by the expre

170 Upon aggregation to embryoid bodies, differentiating ES cells formed large n

171 layed a significant reduction in activity in embryoid bodies, embryos, and adult animals.

172 cultivation in vitro as 3D aggregates called embryoid bodies, ES cells can differentiate into derivat

173 The ID6 line formed embryoid bodies, expressing genes representing all 3 ger

174 different culture systems: FAK+/+ and FAK-/- embryoid bodies, FAK+/+ and FAK-/- endothelial cells, an

175 ion of a primitive streak-like population in embryoid bodies, followed by specification to hematopoie

176 Embryoid bodies, formed from mouse embryonic stem cells,

177 ) cell line H9, when cultured in the form of embryoid bodies, give rise to cells with markers of the

178 e was also reproduced in beta1 integrin-null embryoid bodies, in which primitive endoderm cells segre

179 stem cells compromised their ability to form embryoid bodies, likely because of defects in cell proli

180 lated during development of Nodal-expressing embryoid bodies, nor was there induction of markers for

181 The inducible expression of EWS-FLI1 in embryoid bodies, or collections of differentiating stem

182 ighted morphogenic cell processes within the embryoid bodies, such as cell growth, migration, and int

183 From day-6 embryoid bodies, under the influence of Stat5 signaling,

184 wly developed loss-of-function technology in embryoid bodies, we find that Gata2 and Smad5 cooperate

185 hen slowly decreased upon differentiation to embryoid bodies, whereas 5-methylcytosine levels increas

186 this mark in mouse ESCs and differentiating embryoid bodies.

187 type and mutant ES cells and differentiating embryoid bodies.

188 ive vascular network from SIRT1(-/-)-derived embryoid bodies.

189 ed for protocols based on stromal feeders or embryoid bodies.

190 tion was substantially blunted in Gsk3b(-/-) embryoid bodies.

191 o S phase and mES cells differentiating into embryoid bodies.

192 to promote vascular development in Fgfr1-/- embryoid bodies.

193 ce positioning in Dab2-deficient embryos and embryoid bodies.

194 form a primitive endoderm outer layer in the embryoid bodies.

195 as a floating scaffold to generate elongated embryoid bodies.

196 under hypoxia provided enhanced formation of embryoid bodies.

197 icient at generating neurectoderm-containing embryoid bodies.

198 othelial cell precursors in developing mouse embryoid bodies.

199 LK1(+)CD4(-) cells first arise in developing embryoid bodies.

200 vivo and in embryonic stem (ES) cell-derived embryoid bodies.

201 arker, Hnf4, and prevents cavitation in PSA1 embryoid bodies.

202 tion of, visceral endoderm and cavitation of embryoid bodies.

203 ion factors in nuclear extracts from ES cell embryoid bodies.

204 ptional regulation in murine ES cell-derived embryoid bodies.

205 lian embryogenesis can be studied in ES cell embryoid bodies.

206 for the formation of a basement membrane in embryoid bodies.

207 formed a complex neurite network around the embryoid bodies.

208 xic Hif1a-/- embryonic stem cells and cystic embryoid bodies.

209 mechanism is also adopted in differentiated embryoid bodies.

210 tion both in ES cells and in differentiating embryoid bodies.

211 ection neurons in monolayer culture and from embryoid bodies.

212 ronal differentiation and the utilization of embryoid bodies.

213 , the level of Yes1 was reduced in Etv2 null embryoid bodies.

214 by loss-of-function experiments in chimeric embryoid bodies.

215 Here, a live stem cell derived embryoid body (EB) based cardiac cell syncytium served a

216 d development by means of coculture of CD34+ embryoid body (EB) cells with OP9 stromal cells.

217 ) hPGCLCs [ approximately 43% of FACS-sorted embryoid body (EB) cells] from primed-state induced plur

218 ental patterns of cellular expression during embryoid body (EB) differentiation can address this issu

219 jnk3 genes were derived and submitted to an embryoid body (EB) differentiation protocol.

220 The process of embryoid body (EB) differentiation, like teratoma format

221 of cells present at early and late stages of embryoid body (EB) differentiation.

222 We differentiated hESCs by embryoid body (EB) formation and compared the miR expres

223 Embryoid body (EB) formation is a requisite step in the

224 val, using annexin V staining, and secondary embryoid body (EB) formation were also evaluated.

225 to decreased pluripotency marker expression, embryoid body (EB) formation, cell survival, and loss of

226 er capacity to self-renew based on secondary embryoid body (EB) formation.

227 l fate at the expense of the endoderm during embryoid body (EB) formation.

228 gnificant haploinsufficient determinants for embryoid body (EB) formation.

229 aucity of paraxial mesoderm formation during embryoid body (EB) in vitro differentiation and to the l

230 S and ES cells were differentiated using the embryoid body (EB) method.

231 h the number and the size of beating foci in embryoid body (EB) outgrowths.

232 em (ES) cells undergo differentiation in the embryoid body (EB) system, with peak levels in cell popu

233 stablishment of the blood islands and in the embryoid body (EB)-derived blast-colony-forming cells (B

234 To improve the efficiency of embryoid body (EB)-mediated ES cell differentiation, we

235 PP2 during embryoid body adhesion dramatically increased cardiomyoc

236 as the TaqMan hPSC Scorecard Assay) through embryoid body and directed differentiation experiments a

237 o iPSCs and differentiated into iPSC-CMs via embryoid body and monolayer-based differentiation protoc

238 he activation of developmental regulators in embryoid body assays.

239 activated cell sorting purification of human embryoid body cells differentially expressing endothelia

240 t the growth or viability of ES cell-derived embryoid body cells known to have extinguished TDH expre

241 on of primitive ectoderm and neurectoderm in embryoid body culture.

242 Depletion of Smad1 in embryoid body cultures before hemangioblast commitment l

243 We find that in embryoid body cultures containing even a low ratio of th

244 Using embryoid body cultures of mouse embryonic stem cells, we

245 1 in ES cells and used ES/OP-9 coculture and embryoid body development followed by hematopoietic colo

246 at develops early and is lost quickly during embryoid body development.

247 In an embryoid body differentiation assay, BMP4-dependent diff

248 sion of the transcription factor Pax3 during embryoid body differentiation enhances both paraxial mes

249 nd endothelial progenitor cells by using the embryoid body differentiation method.

250 Using the embryoid body differentiation system, we demonstrate tha

251 ematopoietic lineage (from day 4 to day 6 of embryoid body differentiation) significantly enhances th

252 illary-like structures during late stages of embryoid body differentiation.

253 ce markers, and differentiation potential in embryoid body formation and teratoma assays.

254 ed pluripotent stem cells (hiPSC), bypassing embryoid body formation and the use of exogenous molecul

255 of ectodermal and mesodermal lineages during embryoid body formation and under inductive conditions u

256 l direct plating method in which intervening embryoid body formation does not occur.

257 into multiple hematopoietic lineages during embryoid body formation in vitro, but to date, an ES-der

258 s required embryoid body formation; however, embryoid body formation often results in heterogeneous d

259 Data from embryoid body formation studies indicated that the Mp(-/

260 Embryoid body formation yielded beating cardiomyocyte-li

261 ed almost 30-fold during the first 3 days of embryoid body formation, a culture system model of early

262 ifferent in vitro differentiation protocols (embryoid body formation, endodermal induction, directed

263 for human embryonic stem (hES) cells rely on embryoid body formation, stromal feeder co-culture or se

264 ation from sorted single cells, and enhanced embryoid body formation.

265 ariants prevents the switch and disrupts the embryoid body formation.

266 ull differentiation capacity as indicated by embryoid body formation.

267 ted Nanog levels persisted through 5 days of embryoid body formation.

268 ifferentiation of ES cells in the absence of embryoid body formation.

269 ES cells overlapped with the changes during embryoid body formation.

270 ion of chondrogenesis by human ESCs required embryoid body formation; however, embryoid body formatio

271 The developmental sequence of human embryoid body hematopoiesis is remarkably congruent to t

272 cells into endothelial cells in an in vitro embryoid body is paralleled by an amplification of hepar

273 human iPS clones were differentiated through embryoid body method and MYF5-GFP(+) myogenic cells were

274 Using a modified embryoid body method, we provided gene expression eviden

275 eased on differentiation into differentiated embryoid body or neurospheres.

276 m the drug after an initial treatment aborts embryoid body or teratoma formation.

277 n vitro using the F9 teratocarcinoma derived embryoid body outgrowth system and, show here that PE mi

278 organoid methodology, with modifications of embryoid body size and shape to increase surface area an

279 nalyses, we used an inducible embryonic stem/embryoid body system and observed that ER71 overexpressi

280 hat utilizes the differentiating ES cell and embryoid body system to define the modules and enhancers

281 e ES cells than in differentiating mouse ES (embryoid body, EB) cells.

282 r cell, serum, conditioned culture medium or embryoid body, methods that cannot avoid undefined cultu

283 lly undefined factors including 3D nature of embryoid body, sera from animals, and the feeder cells i

284 For example, embryoid body-based analyses demonstrated that BAF250a-a

285 ls derived from embryonic germ cells, termed embryoid body-derived (EBD) cells, introduced into the C

286 undifferentiated embryonic stem (ES) cells, embryoid body-derived cells (EBCs), or mammalian embryos

287 ntification and characterization of an early embryoid body-derived colony, termed the transitional co

288 We show that embryoid body-derived hematopoietic progenitors expressi

289 In this study, the osteoinductivity of embryoid body-derived material (EBM) was compared to DBM

290 We sought to use human embryoid body-derived stem cells (EBDs) to populate live

291 ive splice variant CoAM in the cavity of the embryoid body.

292 alable two-dimensional method that avoids an embryoid-body intermediate.

293 in mouse embryonic stem cells and from human embryoid-body-derived cells, but not from human adult so

294 Remarkably, anchorage of the embryoid colony from the 3D matrix to collagen-1-coated

295 on into the pseudopregnant mouse uterus, ETX-embryoids efficiently initiate implantation and trigger

296 These ETX-embryoids exhibit lumenogenesis, asymmetric patterns of

297 By taking advantage of this ability, embryoids, organoids and gastruloids have recently been

298 l, termed the post-implantation amniotic sac embryoid (PASE), that recapitulates multiple post-implan

299 l, termed the post-implantation amniotic sac embryoid, to recapitulate early embryogenic events of hu

300 e self-assembled embryo-like structures (ETX-embryoids) using mouse embryonic, trophoblast and extra-