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1 or 2-3 cell layers after Dox induction from embryonic day 0 (E0) to P21 and from E9 to P21, respecti
3 Here, we show that knockout of p75(NTR) from embryonic day 10 (E10) in neural progenitors using a con
5 inally, we found that deletion of HuR before embryonic day 10 disrupts both neocortical lamination an
9 drivers that are activated at early [Nestin; embryonic day 10.5 (E10.5)] and late [human glial fibril
10 ed that Cdh5(-/-)GFP(+/+) HSCs emerging from embryonic day 10.5 and 11.5 (E10.5 and E11.5) AGM or der
12 arly mouse embryos but begins to increase at embryonic day 10.5 and remains elevated through birth.
13 ryonic stem cell colony-forming assay and in embryonic day 10.5 aorta-gonad-mesonephros explants.
15 This panel was then applied against single embryonic day 10.5 heart cells to demonstrate its abilit
18 ic cultures, named pancreatoids, composed of embryonic day 10.5 murine epithelial progenitors and nat
19 een both cell lines and resemblance to mouse embryonic day 10.5 otocyst cells implied reasonable robu
20 Geminin mutant versus wild-type siblings at embryonic day 10.5 revealed decreased expression of key
23 beta at Ser-9 starting early in development (embryonic day 10.5), leading to enhanced GSK3beta activi
24 racerebroventricular macrophages arrive from embryonic day 10.5, and can traverse ventricular walls i
25 se embryos, is important for survival before embryonic day 10.5, but its function in embryos is unkno
26 use NP with in utero microelectroporation at embryonic day 10.5, close to the estimated peak of area
29 merge from neuroepithelial stem cells around embryonic day 11 and produce excitatory cortical neurons
30 r chimerism that continuously increases from embryonic day 11 onward, sometimes even taking over enti
31 placental vulnerability is pronounced before embryonic day 11, when even mild immune challenge result
32 sequenced more than 52,500 single cells from embryonic day 11.5 (E11.5) postembryonic day 5 (P5) gona
34 xtrastriolar (MES) regions of the utricle at embryonic day 11.5 (E11.5), while cells in the lateral e
36 VGluT2 was detectable in most DA neurons at embryonic day 11.5 and was localized in developing axons
37 lts in congestive heart failure and death by embryonic day 11.5 as a result of hypoproliferation of t
38 sors in the mouse dentate neuroepithelium at embryonic day 11.5 give rise to proliferative Hopx(+) ne
39 axon tracts require Fz3 function as early as embryonic day 11.5, and that Fz3 is required for pathfin
40 pulse into Connexin30(-/-) mouse otocysts at embryonic day 11.5, is able to prevent putative hearing
41 hat ventricular injection of FGF2 protein at embryonic day 11.5-before neurogenesis and before the fo
44 and non-ENS gut cells of mice, collected at embryonic days 11.5 and 15.5, when different subtypes of
45 led a localized domain of Zic1 expression at embryonic days 11.5-12.5 in a region overlapping the sup
46 use RGCs shortly after they differentiate at embryonic day 12 and is essential for multiple aspects o
47 transcriptome analyses of 14,441 cells from embryonic day 12 submandibular and parotid salivary glan
49 of the first epithelial stalk at early-stage embryonic day 12.5 (E12.5) according to both TUNEL stain
50 y, we isolated palatal mesenchyme cells from embryonic day 12.5 (E12.5) and E13.5 Osr2(RFP/+) and Osr
51 resence by acetylcholinesterase staining and embryonic day 12.5 (E12.5) intestine transcriptome by RN
52 ivity for mouse liver tissues collected from embryonic day 12.5 (E12.5) to postnatal week 8 (W8), enc
53 ls results in the cessation of myogenesis by embryonic day 12.5 (E12.5), as assayed by myosin heavy c
54 Reduced pericyte coverage was observed at embryonic day 12.5 and persisted throughout development,
55 were isolated from Shh-cre;ROSA:YFP mice at embryonic day 12.5 and postnatal day 0, representing opp
56 s, mouse cochlear cultures were initiated at embryonic day 12.5 and subjected to pharmacological trea
57 recipitation against Lmx1b in mouse limbs at embryonic day 12.5 followed by next-generation sequencin
60 y continued to receive these chemicals until embryonic day 12.5, whereupon placental samples were col
61 e small guanosine triphosphatase RSG1 die at embryonic day 12.5, with developmental abnormalities cha
67 at the onset of gonadal sex determination at embryonic day 13 (E13) and after cord formation in the t
68 s as they develop in the mouse brain between embryonic day 13 and postnatal day 5 in order to identif
69 ular function of this factor was examined in embryonic day 13 hepatoblast culture with maturation fac
70 ient Area X-CB+ domain became discernable at embryonic day 13 in the Islet1-ventral striatal field.
71 1 and JM-a CYT-2 was first detectable around embryonic day 13 in the mouse, mainly in the collecting
72 etion of Pou4f1 in SGNs beginning in mice at embryonic day 13 rescues the early path-finding and apop
73 ka virus at embryonic day 6 and evaluated at embryonic day 13 show markedly diminished levels of vira
74 The pregnant rats were injected with BrdU at embryonic day 13, and their fetuses were sacrificed from
75 cavity immediately surrounding the embryo on embryonic day 13-13.5 (E13-13.5) corrected pre-mRNA spli
76 oinjection into the mouse amniotic cavity at embryonic day 13-13.5, reduces target RNA expression for
78 this master regulatory locus is activated at embryonic day 13.5 (E13.5) by an early enhancer (EE), wh
79 that PACAP was an anti-mitogenic signal from embryonic day 13.5 (E13.5) onward both in culture and in
80 ssion was inhibited during erythropoiesis in embryonic day 13.5 and embryonic day 18.5 fetal liver an
82 of the lateral ganglionic eminence (LGE) at embryonic day 13.5 may underlie such deficits by inducin
83 served DNA regulatory enhancer (Dlx5/6ei) in embryonic day 13.5 medial ganglionic eminence (E13.5 MGE
84 posterior regions of the palatal shelves in embryonic day 13.5 Pax9-deficent embryos in comparison w
88 Adar1(E861A/E861A) embryos died at ~E13.5 (embryonic day 13.5), with activated interferon and doubl
89 tal, and acinar cells but become bipotent by embryonic day 13.5, giving rise to endocrine cells and d
91 Trpm7 deletion late in cardiogenesis (about embryonic day 13; alphaMHC-Cre) produces viable mice wit
93 L/6J mice were intraperitoneally injected on embryonic days 13 and 17 each with 240mug of human monoc
95 xpressed during mouse brain development from embryonic day 14 (E14), peaked around the time of birth,
96 uire action potential-generating capacity at embryonic day 14 (E14), the earliest age tested, and act
99 We compared the gene expression profiles of embryonic day 14.5 (E14.5) Yap conditional knockout and
100 cantly decreased in Cln5-/- mouse embryos at embryonic day 14.5 (E14.5), and expression of Tuj1, an i
103 ding mice mating, two-cell embryo injection, embryonic day 14.5 embryo digestion, fluorescence-activa
105 cells of edited and nonedited blastomeres at embryonic day 14.5 showed that off-target single-nucleot
106 erebral cortex at a progenitor driven phase (embryonic day 14.5) and at birth-after neurons from all
107 deletion at the onset of differentiation, at embryonic day 14.5, disrupted Hensen's cell formation.
108 ssels and follicle progenitor cells began by embryonic day 14.5, when nascent hair placodes had blood
109 tbp4, Matn1, Matn3, and Tpo-was decreased at embryonic day 14.5, while levels of apoptotic proteins w
114 ng rat development, which take place between embryonic days 14 and 18 (E14-E18) and E20-E21, have bee
116 pses from late prenatal mouse embryo stages (embryonic days 14-18) into adulthood [postnatal day (P)4
117 ce were analyzed with MR imaging at 9.4 T on embryonic days 14.5 (eight dams and 58 fetuses; imprinti
120 mutant fetal testes of 129Sv and B6 mice at embryonic day 15.5 (E15.5), prior to overt tumorigenesis
123 rebrain neuron cell body size is apparent in embryonic day 15.5 fetuses, and persists until postnatal
124 1, age and sex-matched euploid controls, and embryonic day 15.5 forebrains from Ts1Cje, Ts65Dn, and D
125 2 is expressed broadly by progenitors in the embryonic day 15.5 subventricular zone, during the peak
126 ransgenic mice during a critical period from embryonic day 15.5 to postnatal day 14 was accompanied b
133 stematic comparisons between different ages (embryonic days 15 and 18, postnatal day 8, and adult), w
134 stologic sections of the vertebral column at embryonic days 15.5 and 17.5 revealed an abnormal organi
138 is pathway occurs in late gestation at about embryonic day 16 and requires the photopigment in the fe
141 the Ets transcription factor Erg die between embryonic day 16.5 and 3 months of age as a result of pu
142 using hematopoietic progenitors from either embryonic day 16.5 Cdk5(+/+) or Cdk5(-/-) embryos to ena
144 size of the pancreas in Ucp2(-/-) fetuses at embryonic day 16.5, associated with a higher number of a
145 ing occurs and is down-regulated starting at embryonic day 16.5, concurrent with the onset of termina
147 ation in dental epithelium and mesenchyme at embryonic day 16.5; however, the cell apoptosis is unaff
149 tion of the left uterine vascular pedicle at embryonic day 17 of gestation was validated by weighing
154 bral cortex, waves of activity occur between embryonic day 18 and postnatal day 8 and originate in pa
161 or basal and starvation-induced autophagy in embryonic day 18.5 BAT3(-/-) mouse embryos and in mouse
162 ing erythropoiesis in embryonic day 13.5 and embryonic day 18.5 fetal liver and adult spleen and bone
164 is a critical perinatal window, ranging from embryonic day 18.5 to postnatal day 14 in mice, in which
165 naive female mice, the weight of fetuses at embryonic day 18.5 was significantly reduced compared wi
166 mbryos obtained through Caesarean section at embryonic day 18.5 were cyanotic, suffered from respirat
168 wn that the proliferation of late gestation (embryonic day 19) fetal rat hepatocytes is mitogen-indep
170 were administered into the amniotic space at Embryonic Day 20 or after birth by intraperitoneal injec
171 sly, we showed ethanol treatment of cultured embryonic day 20 septal neurons distorts the maturation
172 ed into the amniotic sac of pregnant rats at Embryonic Day 20 to simulate antenatal models of chorioa
173 pregnant rats by intraamniotic injection at Embryonic Day 20, and pups were delivered by cesarean se
175 Pups were delivered by cesarean section at Embryonic Day 22 and treated with rhIGF-1/BP3 (0.02-20 m
177 we used a rabbit model and compared preterm [embryonic day 29 (E29), 3 d old] and term (E32, <2 h old
178 pluripotent state of the inner cell mass at embryonic day 3.5 (E3.5) and the induction of let-7 upon
179 cells from eight-cell embryos and individual embryonic day 3.5 blastocysts showed unexpectedly variab
180 Et, increases daily for heart to 1-2 kPa by embryonic day 4 (E4), and although this is ~10-fold soft
182 r emerges at the distal tip of the embryo at embryonic day 5.5 and translocates to the prospective an
184 pregnant mice challenged with Zika virus at embryonic day 6 and evaluated at embryonic day 13 show m
185 en shown to result in embryonic lethality at embryonic day 6.5 (E6.5) before blood vessel formation.
186 rs in ectoderm are already pre-accessible in embryonic day 6.5 (E6.5) Epi when cells enter a primed p
195 +)Flk1(+) mesodermal precursor population at embryonic day 7.5 (E7.5), a cell fraction also endowed w
196 ppa2 and Dppa4, which remain expressed until embryonic day 7.5 (E7.5), when their promoters are remet
198 of up to 60% of cardiac progenitor cells at embryonic day 7.5 was well tolerated and permitted embry
202 949, and 1,166 single murine heart cells at embryonic day 8.5 (e8.5), e9.5, and e10.5, respectively.
205 active specifically in the cardiac inflow at embryonic day 8.5 and throughout later SAN development a
206 tently, many mutant embryos that survived to embryonic day 8.5 displayed defects in ventral closure o
208 in the telencephalon and anterior retina at embryonic day 8.5 triggered upregulation of the p53 effe
209 within a critical developmental time window (embryonic day 8.5-10.5), when NT patterning and closure
211 ics" or "lower dose plastics" mixture during embryonic days 8 to 14 of gonadal sex determination and
214 (+) cKit(-) endothelial cells harvested from embryonic day 9 (E9) aorta-gonad-mesonephros (AGM) regio
215 myocytes to a similar degree (50% to 60%) at embryonic day 9.0 could be fully rescued by residual myo
216 newal, leading to embryonic lethality before embryonic day 9.0, a developmental stage equivalent to t
217 3 INs were organized into either early-born [embryonic day 9.5 (E9.5) to E10.5] or late-born (E11.5-E
218 d that V3 INs are organized into early-born [embryonic day 9.5 (E9.5) to E10.5] or late-born (E11.5-E
220 cells isolated at seven time points spanning embryonic day 9.5 (primordial heart tube) to postnatal d
222 imultaneously colonize the whole embryo from embryonic day 9.5 in a chemokine-receptor-dependent mann
227 otential upon early hematopoietic tissues at embryonic day 9.5, an embryonic stage not previously des
235 enX (0, 2, or 10 mg/kg) via oral gavage from embryonic day (E) 1.5 to 11.5 or 17.5 to evaluate exposu
240 Tsc1 deletion within thalamic precursors at embryonic day (E) 12.5 disrupts thalamic circuitry and a
243 r cells (NPCs), the cell cycle slows between embryonic day (E) 13.5 and E15.5 while other embryonic N
245 on into the myocardium were impaired between embryonic day (E) 13.5 to 15.5 in mutant hearts because
246 type 5% w/w ethanol consumption regimen from embryonic day (E) 13.5-16.5, spanning the peak of cortic
247 Whole-genome RNA-sequencing analysis of embryonic day (E) 14.5 cap stage molars revealed reducti
248 pseudostratified epithelium prior to murine embryonic day (E) 14.5 to an exquisitely folded columnar
249 ontrast, fetal steady-state hematopoiesis at embryonic day (E) 14.5 was not affected by homozygous Mo
251 pparent late in development, but that before embryonic day (E) 15, fetal blood neutrophils display li
252 rain regions across nine perinatal ages from embryonic day (E) 17 to postnatal day (P) 11 and found t
254 utamate) K(mf) ) was significantly higher at embryonic day (E) 18.5, in line with increased expressio
256 inences (CGEs) between preterm-born [born on embryonic day (E) 29; examined on postnatal day (D) 3 an
257 s lineage markers such as Nanog and Gata6 at embryonic day (E) 3.25, and the EPI and PrE precursor ce
258 express the Sry-type HMG box gene Sox17 from embryonic day (E) 7.5 to E8.5 specifically differentiate
262 5hmC initiates asynchronously among PGCs at embryonic day (E) 9.5 to E10.5 and accounts for the uniq
264 gh-frequency sounds) born early around mouse embryonic day (E) 9.5-10.5, and those in the apex (respo
265 After the completion of neurogenesis around embryonic day (E) 90, when the cerebrum is still lissenc
267 As a result of a low choline supply between embryonic day (E)11 and E17 of gestation, the number of
268 nergic (YFP+) neurons were first detected at embryonic day (E)11.5, and the proportion of cholinergic
269 nitors were delayed in forming two layers at embryonic day (E)13.5 when embryonic skin begins to stra
271 s from heterozygous (Hsd11b(+/-)) matings at embryonic day (E)14.5 and E17.5, where all three genotyp
272 uced preterm birth in timed pregnant C57BL/6 embryonic day (E)15.5 mice and rescues their pups from s
274 function in both SMGRKO and GR(-/-) mice at embryonic day (E)17.5, associated with generalized oedem
276 eoxyuridine (BrdU) at various stages between embryonic day (E)3 and E16 and killing animals at postna
277 Expression and localization of polySia in embryonic day (E)5-14 chick eyefronts and E9 trigeminal
279 lyzed 45,334 single-cell transcriptomes from embryonic day (E)7.5, when endoderm progenitors are spec
280 d the miRNA and gene expression profiles for embryonic day (E)8.5 endoderm, E14.5 Dlk1(+) liver cells
281 NCAM and ST8SiaII mRNA transcripts peaked by embryonic day (E)9, remained steady between E10 and E14
282 -gonad-mesonephros region, and visualized at embryonic day (E)9.0 in the yolk sac and neuroectoderm;
283 3-induced embryonic stem cells and Pax3-null embryonic day (E)9.5 mouse embryos, we identified conser
284 alysis of post-implantation conceptuses from embryonic day (E)9.5 to E13.5 revealed poorly developed
286 ouse B1 cell precursors are produced between embryonic days (E) 13.5 and 15.5 and remain largely quie
289 de neurons (peak cell cycle exit for both at embryonic day [E]12.5-E13.5), tyrosine hydroxylase neuro
291 ue fetuses to x-rays during early gestation (embryonic day [E]30-E42), i.e., before the onset of cort
292 cells during the period of RGC neurogenesis (embryonic day, E, 12.5 to 18.5) when the RPE is closely
293 genetrap allele was embryonic lethal before embryonic day E10.5, whereas the heterozygous condition
297 ryo serotonin levels and neurodevelopment at embryonic day E14.5, when peripheral sources of 5-HT pre
298 the 32- to 64-cell mouse embryo transition, Embryonic day (E3.25), whose study in literature is conc
299 landscapes in mouse forebrain precursors at embryonic days E8.5 and E10.5 (before and after neural t