ライフサイエンスコーパス: embryonic fibroblast

1 hance copper accumulation in Ctr1(-/-) mouse embryonic fibroblasts.

2 s-links in Fkbp10-null and -wild-type murine embryonic fibroblasts.

3 ntiation is increased in Id1-deficient mouse embryonic fibroblasts.

4 ines: human embryonic kidney cells and mouse embryonic fibroblasts.

5 cell death in Bax/Bak1 double-deleted mouse embryonic fibroblasts.

6 PGC-1alpha modulates the secretome of mouse embryonic fibroblasts.

7 gene- and transcript-targeted primary mouse embryonic fibroblasts.

8 rogramming potential of Tet2-deficient mouse embryonic fibroblasts.

9 d initiation of inflammation in Mus musculus embryonic fibroblasts.

10 adipogenesis is enhanced in Rnf146-/- mouse embryonic fibroblasts.

11 with wild-type and pol kappa deficient mouse embryonic fibroblasts.

12 not K-Ras(G12V) induced senescence in mouse embryonic fibroblasts.

13 n intermediate between pro-B cells and mouse embryonic fibroblasts.

14 chromatin structure of Ku70-deficient mouse embryonic fibroblasts.

15 tumor cells and in the Ras-transformed mouse embryonic fibroblasts.

16 s characterized half-life in mouse and human embryonic fibroblasts.

17 is determined by the number and position of embryonic fibroblasts.

18 y feature of Tet1/Tet2 double-knockout mouse embryonic fibroblasts.

19 l-time transport of beta-actin mRNA in mouse embryonic fibroblasts.

20 impact on gene expression of arrested mouse embryonic fibroblasts.

21 rious cultured human cell lines and in mouse embryonic fibroblasts.

22 tor forces in live human platelets and mouse embryonic fibroblasts.

23 dogenous MS2-tagged beta-actin mRNA in mouse embryonic fibroblasts.

24 42 kDa exon alpha Pol beta variant in mouse embryonic fibroblasts.

25 D2, and increased caveolar mobility in mouse embryonic fibroblasts.

26 e-derived macrophages, HeLa cells, and mouse embryonic fibroblasts.

27 12, or 14 in tetraploid immortalized murine embryonic fibroblasts.

28 we analyze de novo DNA methylation in mouse embryonic fibroblasts (2i-MEFs) derived from DNA-hypomet

29 5N1, H1N1, H9N2)in three cell types (chicken embryonic fibroblasts, A549, and MDCK).

30 l cells (mLNSCs) to a previously undescribed embryonic fibroblast activation protein-alpha (FAP)(+) p

31 h1, Pou4f3, and Gfi1) that can convert mouse embryonic fibroblasts, adult tail-tip fibroblasts and po

32 tion density in transcription units in mouse embryonic fibroblasts also correlated strongly with intr

33 Flux assays in Mpc1-deficient embryonic fibroblasts also reflected these changes, incl

34 In addition, Hipk2 (-/-) neurons and mouse embryonic fibroblasts also show increased expression of

35 Utilizing mouse embryonic fibroblast and cancer cell line models, here w

36 We found that Plp2-deficient mouse embryonic fibroblast and human fibroblasts carrying PLP2

37 ck hypoxia-induced Fbln5 expression in mouse embryonic fibroblasts and 3T3 fibroblasts.

38 mming efficiency of adult-derived but not of embryonic fibroblasts and also enhanced functional matur

39 Here, using mouse embryonic fibroblasts and an array of biochemical method

40 y 10000 regions of OG enrichment in WT mouse embryonic fibroblasts and approximately 18000 regions wh

41 We validate our method by imaging mouse embryonic fibroblasts and BON cells.

42 reduced colony formation of Fan1(-/-) mouse embryonic fibroblasts and bone marrow mesenchymal stem c

43 Genetic ablation of MST1 in mouse embryonic fibroblasts and bone marrow-derived macrophage

44 sion is markedly reduced in TAp63-null mouse embryonic fibroblasts and brown adipose tissues and by t

45 nd increases susceptibility to cell death in embryonic fibroblasts and cardiac myocytes.

46 severity and infectivity in primary chicken embryonic fibroblasts and chickens.

47 to be SIRT1-dependent in proliferating mouse embryonic fibroblasts and differentiating human SW872 pr

48 lls, we deleted ELMOD2 in immortalized mouse embryonic fibroblasts and discovered a number of cellula

49 assays were performed with IQGAP1-null mouse embryonic fibroblasts and HEK293 cells with IQGAP1 knock

50 GF stimulation at conserved serines in mouse embryonic fibroblasts and HEK293 cells.

51 tion were normal in Clec16a-deficient murine embryonic fibroblasts and HeLa cells.

52 level, Brpf1 loss inhibits proliferation of embryonic fibroblasts and hematopoietic progenitors.

53 by 3-16 folds in primary mouse macrophages, embryonic fibroblasts and human cell lines.

54 ontin and other FN-type matrix in both mouse embryonic fibroblasts and human melanoma.

55 n immortalization of Rb1 (-/-) primary mouse embryonic fibroblasts and in aggressive tumor growth in

56 mitochondrial respiratory complexes in mouse embryonic fibroblasts and in the striatum, a brain regio

57 utant Kras homozygous and heterozygous mouse embryonic fibroblasts and lung cancer cells, that these

58 This phenotype was also seen in both mouse embryonic fibroblasts and mesangial cells.

59 Investigation using Dab2-deficient embryonic fibroblasts and mesenchymal stromal cells indi

60 Furthermore, Reep1-/- embryonic fibroblasts and neurons in the cerebral cortex

61 G12V))-induced premature senescence in mouse embryonic fibroblasts and normal human bronchial epithel

62 s, and Ets2 is sufficient to reprogram mouse embryonic fibroblasts and post-natal tail-tip-derived fi

63 Cytogenetic analysis of mouse embryonic fibroblasts and pre-malignant B cells demonstr

64 n of IP3R3 is accelerated in Pten(-/-) mouse embryonic fibroblasts and PTEN-null cancer cells.

65 When overexpressed in both mouse embryonic fibroblasts and rat OPCs (rOPCs), cell cycle a

66 ogen-driven immortalization of primary mouse embryonic fibroblasts and recapitulates early steps of c

67 ATP depletion to incite cell stress in mouse embryonic fibroblasts and renal proximal tubular cells,

68 ic sphingoid long-chain bases accumulated in embryonic fibroblasts and spinal cords from wobbler mice

69 Incubation of mouse embryonic fibroblasts and T cells with transforming grow

70 n of GRB10 in nontumorigenic PTEN null mouse embryonic fibroblasts and tumorigenic PCa cell lines red

71 ized dimensions, surrounded by 3T3-J2 murine embryonic fibroblasts, and then sandwiched with a thin l

72 ic approach showed that ARH3-deficient mouse embryonic fibroblasts are characterized by a specific in

73 Consistently, AIP-deficient murine embryonic fibroblasts are highly resistant to virus infe

74 il chromatin accessibility dynamics as mouse embryonic fibroblasts are reprogrammed into induced plur

75 We used mouse embryonic fibroblasts as a system to determine the effec

76 overed new roadblocks in reprogramming mouse embryonic fibroblasts as pluripotent stem cells, disting

77 istic target of rapamycin signaling in mouse embryonic fibroblasts as well as in muscle and liver tis

78 ation, redox state and migration using mouse embryonic fibroblast Balb/3T3, human dermal fibroblast N

79 In the case of mouse embryonic fibroblasts, BER of the Sp lesion is strongly

80 at Orai1 is a dimer in resting primary mouse embryonic fibroblasts but displays variable stoichiometr

81 Expression is not detected in C3H10T1/2 embryonic fibroblasts but is successively higher in preo

82 ly induces the cardiac gene program in mouse embryonic fibroblasts but not adult fibroblasts.

83 ratio was rescued in FKBP65-deficient murine embryonic fibroblasts by reconstitution with wild-type b

84 Metabolic analysis of MDV-infected chicken embryonic fibroblasts (CEFs) identified elevated levels

85 eomes extracted from Escherichia coli, mouse embryonic fibroblast cell cultures, and Arabidopsis thal

86 l structures of a mitochondrion from a mouse embryonic fibroblast cell line (NIH3T3) were visualized

87 Cry1 (-/-) Cry2 (-/-) double knockout mouse embryonic fibroblast cell line.

88 eta1 expression, we examined IPMK(-/-) mouse embryonic fibroblast cells and found that integrins beta

89 er TEM8 was further demonstrated using mouse embryonic fibroblast cells and mice deficient in the CMG

90 6S proteasomes purified from wild-type mouse embryonic fibroblast cells and those lacking Usp14.

91 usly (3T9) or virus-(SV40) transformed mouse embryonic fibroblast cells as targets.

92 Interestingly, in mouse embryonic fibroblast cells derived from CIZ1-null embryo

93 We investigated this question using mouse embryonic fibroblast cells expressing wild-type PKR (PKR

94 We report here that murine embryonic fibroblast cells from ZAP knockout mice suppor

95 s was not affected in SV40-transformed mouse embryonic fibroblast cells lacking Bak/Bax.

96 Although S187A mouse embryonic fibroblast cells showed normal proliferation u

97 nor fraction (30-40%) of the 26S in WT mouse embryonic fibroblast cells.

98 glycolytic products in both tumor and mouse embryonic fibroblast cells.

99 D-induced differentiation of 4.1R(-/-) mouse embryonic fibroblast cells.

100 Mouse embryonic fibroblasts challenged with TPZ or Cu(OP)2 als

101 tion but is dispensable for kidney and mouse embryonic fibroblast ciliary formation.

102 88/IFN-beta promoter stimulator 1(-/-) mouse embryonic fibroblasts completely lacked antiviral activi

103 of the RIPK1 mutants D325V or D325H in mouse embryonic fibroblasts confers not only increased sensiti

104 We used murine embryonic fibroblasts containing a doxycycline-inducible

105 Experiments carried out in mouse embryonic fibroblasts corroborated these findings.

106 Additionally, whereas WT mouse embryonic fibroblasts could be reprogrammed to a state o

107 Analysis of wounds and mouse embryonic fibroblast cultures showed that EMILIN-1 and -

108 cell-based complementation studies in mouse embryonic fibroblast deficient for Esco1 and Esco2, as a

109 WT KRAS to rescue the growth defect of mouse embryonic fibroblasts deficient in all Ras genes.

110 Here we show that mouse embryonic fibroblasts deficient in Bax/Bak1 are resistan

111 is not important for proliferation of murine embryonic fibroblasts, demonstrating that NKAP functions

112 In vitro experiments using cultured embryonic fibroblasts derived from IFN receptor knockout

113 Nphp5(-/-) mouse embryonic fibroblast developed normal cilia, and Nphp5(-

114 I gene from lambda phage in transgenic mouse embryonic fibroblasts during the transition from primary

115 ecreased senescence of hepatocytes and mouse embryonic fibroblasts, effects that were blocked by trea

116 eep sequencing of small RNA molecules in the embryonic fibroblasts, embryonic stem cells, and induced

117 RepID-depleted murine embryonic fibroblasts exhibit abnormal replication fork

118 Here, we discovered that Ate1-knockout (KO) embryonic fibroblasts exhibit tumorigenic properties, in

119 pry1(-/-) and Spry2(-/-) double mutant mouse embryonic fibroblasts exhibited decreased cell migration

120 that deletion of Ada3 from Ada3(FL/FL) mouse embryonic fibroblasts exhibited various chromosome segre

121 Whereas Bok(-/-) mouse embryonic fibroblasts exposed to thapsigargin, A23187, b

122 doses; however, in the Ku70-deficient mouse embryonic fibroblasts, exposure to a high dose of BPA wa

123 Tsc1(-/-) and Tsc2(-/-) mouse embryonic fibroblasts expressed higher uPA levels than t

124 y diverse fatty acyl donor analogs and mouse embryonic fibroblasts expressing PORCN protein from diff

125 More importantly, mouse embryonic fibroblasts expressing the SMURF2 S384A mutant

126 lture platforms: feeder-free Matrigel, mouse embryonic fibroblast feeders, and Matrigel replated on f

127 Calnexin deficiency as studied in mouse embryonic fibroblasts from calnexin(-/-)mice or in respo

128 Experiments using embryonic fibroblasts from CyclinA2-LacZ-floxed-EGFP, or

129 -related GTPase (IRGM1) was overexpressed in embryonic fibroblasts from dynamin1 like (DNM1L) protein

130 Analysis of embryonic fibroblasts from GFP reporter mice indicates t

131 Similarly, mouse embryonic fibroblasts from Mcub(-/-) mice were more sens

132 Here we used mouse embryonic fibroblasts from mice deficient in FAM134B to

133 epithelial tissues from patients with CD and embryonic fibroblasts from mice, along with enteroids an

134 on of reactive oxygen species were higher in embryonic fibroblasts from Mpv17(-/-) mice.

135 ility were observed at a higher frequency in embryonic fibroblasts from Neil2-null mice than from the

136 ysis of cultured mesoderm explants and mouse embryonic fibroblasts from null mutants shows that the m

137 IRGM1 was overexpressed in embryonic fibroblasts from receptor interacting serine/t

138 vestigate integrin beta3 and paxillin in rat embryonic fibroblasts growing on two different extracell

139 uced in Cln3(Deltaex1) (-) (6)-derived mouse embryonic fibroblasts have visibly disorganized membrane

140 We developed an immortalized mouse embryonic fibroblast (iMEF) line in which full-length wi

141 n transfected cells and MDV-infected chicken embryonic fibroblasts in a phosphorylation-dependent man

142 itochondrial fission when expressed in mouse embryonic fibroblasts in the absence of additional stres

143 N-I production and NiV replication in murine embryonic fibroblasts in vitro, and the redundant but es

144 d pluripotent stem cells (iPSCs) from murine embryonic fibroblasts, in the absence of p53.

145 f RhoA signaling-mediated processes in mouse embryonic fibroblasts, including stress fiber formation

146 can sensitize breast cancer cells and mouse embryonic fibroblasts into entering paclitaxel-induced s

147 a or Rho-associated kinase pathways converts embryonic fibroblasts into functional cardiomyocyte-like

148 c-Myc) or Oct4 during reprogramming of mouse embryonic fibroblasts into iPSCs.

149 relocation of Xi in CIZ1-null primary mouse embryonic fibroblasts is accompanied by loss of PRC-medi

150 hat SV40 TAg-induced transformation in mouse embryonic fibroblasts is independent of activator E2Fs.

151 2 agonist killer (BAK) double-knockout mouse embryonic fibroblasts, its location was solely cytoplasm

152 We examined mouse embryonic fibroblasts lacking Atg16l1 (ATG16L1 KO mouse

153 Complementation experiments in mouse embryonic fibroblasts lacking beta-arrestins combined wi

154 B1 induces chromosomal instability in mouse embryonic fibroblasts lacking both Tp53 and Rb1.

155 e and NLS-mutated pol beta(R4S,K5S) in mouse embryonic fibroblasts lacking endogenous pol beta.

156 Analysis of replicating mitochondrial DNA in embryonic fibroblasts lacking RNase H1 reveals retention

157 we found that inactivation of Flcn in mouse embryonic fibroblasts leads to changes in multiple Wnt l

158 experiments in cultured Oma1-deficient mouse embryonic fibroblasts link together impeded supercomplex

159 Herein, we demonstrated that, in mouse embryonic fibroblasts, loss of LKB1 and transduction of

160 o-cultures (MPCCs) of PHHs and 3T3-J2 murine embryonic fibroblasts maintain insulin-sensitive glucose

161 biogenesis and function of EVs using a mouse embryonic fibroblast (MEF) cell line that can be induced

162 Here we label the endogenous Pol II in mouse embryonic fibroblast (MEF) cells using the CRISPR/Cas9 g

163 In mouse embryonic fibroblast (MEF) cells we show that Prom1 is r

164 Using an established mouse embryonic fibroblast (MEF) model combining p53 inactivat

165 Using mouse embryonic fibroblast (MEF) models that generate inducibl

166 a spanning nearly two cell cycles from Mouse Embryonic Fibroblast (MEF) primary cells.

167 Arpp19 ablation dramatically decreased mouse embryonic fibroblast (MEF) viability by perturbing the t

168 36 trimethyltransferase SETD2 knockout mouse embryonic fibroblasts (MEF) cells.

169 Moreover, primary Rad18(-/-) mouse embryonic fibroblasts (MEF) retained robust Fancd2 mono-

170 signaling were restored in ATG16L1 KO mouse embryonic fibroblasts (MEF) upon proteasome inhibition.

171 E359K mouse embryonic fibroblasts (MEF) were more sensitive to DNA c

172 Here using mouse embryonic fibroblasts (MEF), we investigate the ciliary

173 formation using G0s2-null immortalized mouse embryonic fibroblasts (MEF).

174 g on wild-type and beta-actin knockout mouse embryonic fibroblasts (MEFs) after reprograming to adipo

175 racterized CENP-F(+/+) and CENP-F(-/-) mouse embryonic fibroblasts (MEFs) and found drastic differenc

176 Mouse embryonic fibroblasts (MEFs) and hepatocytes from Ccne1(

177 logical state space of a population of mouse embryonic fibroblasts (MEFs) and identify topographical

178 impairs the proliferative potential of mouse embryonic fibroblasts (MEFs) and is associated with a si

179 correlated with H3K9me2 in interphase murine embryonic fibroblasts (MEFs) and is restricted to intrag

180 thylation (H3K27me3) in both Pten null mouse embryonic fibroblasts (MEFs) and Pten null mouse prostat

181 rated PCBP2-deficient mice and primary mouse embryonic fibroblasts (MEFs) and showed that loss of PCB

182 and represses fatty acid oxidation in mouse embryonic fibroblasts (MEFs) by targeting the AMP-activa

183 length over mitochondria in Drp1-null mouse embryonic fibroblasts (MEFs) compared to wild-type (wt)

184 nonmitochondrial PB2 is attenuated in mouse embryonic fibroblasts (MEFs) compared with an isogenic v

185 EGR1(-/-) mouse embryonic fibroblasts (MEFs) demonstrated lower suscepti

186 was absent in the conditioned media of mouse embryonic fibroblasts (MEFs) derived from Fam20a knock-o

187 re we show that primary adipocytes and mouse embryonic fibroblasts (MEFs) derived from FTO overexpres

188 We demonstrate that mouse embryonic fibroblasts (MEFs) derived from Hace1(-/-) mic

189 ow that positioning of mitochondria in mouse embryonic fibroblasts (MEFs) determines the shape of int

190 Moreover, PGAM5 deficient mouse embryonic fibroblasts (MEFs) exhibited decreased phospho

191 Mechanistically, Tmem30a-mutant mouse embryonic fibroblasts (MEFs) exhibited diminished PS fli

192 cell cycle progression in immortalized mouse embryonic fibroblasts (MEFs) from PINK1(-/-) mice, and i

193 Mouse embryonic fibroblasts (MEFs) from the double knockout em

194 e SRSF6 levels further, we established mouse embryonic fibroblasts (MEFs) from wild type, zQ175, and

195 nsistent with these results, Atf3(-/-) mouse embryonic fibroblasts (MEFs) had more aberrant chromosom

196 rotein kinase 2 (HIPK2) in neurons and mouse embryonic fibroblasts (MEFs) has a broad protective effe

197 hat lysates from Nedd4-1 knockout (KO) mouse embryonic fibroblasts (MEFs) have significantly diminish

198 e late mitotic stages NPCs in vivo and mouse embryonic fibroblasts (MEFs) in vitro from Pafah1b1-defi

199 both breast cancer (BC) cell lines and mouse embryonic fibroblasts (MEFs) induces oversized cells con

200 e tract binding protein PTB to convert mouse embryonic fibroblasts (MEFs) into functional neurons.

201 Proliferation of primary Ola1(-/-) mouse embryonic fibroblasts (MEFs) is impaired due to defectiv

202 Murine embryonic fibroblasts (MEFs) lacking Fyn and cells in wh

203 Mouse embryonic fibroblasts (MEFs) or primary adult cardiac fi

204 Cebpg(-/-) mouse embryonic fibroblasts (MEFs) proliferate poorly and exhi

205 ffected individuals and Cdk10-knockout mouse embryonic fibroblasts (MEFs) proliferated normally; howe

206 C1qbp(-/-) mouse embryonic fibroblasts (MEFs) resembled the human disease

207 of PDAC cancer cells and SerpinB2(-/-) mouse embryonic fibroblasts (MEFs) resulted in increased tumou

208 ort that Cdc14B knockout (Cdc14B(-/-)) mouse embryonic fibroblasts (MEFs) showed defects in repairing

209 compared gene expression in STAT3-null mouse embryonic fibroblasts (MEFs) stably expressing wild-type

210 hibitor to either mouse macrophages or mouse embryonic fibroblasts (MEFs) suppressed IFN-beta and TNF

211 e cells, maintain the DHS landscape of mouse embryonic fibroblasts (MEFs) synergistically.

212 Here, we show in mouse embryonic fibroblasts (MEFs) that this MNNG-dependent ph

213 kout screen in Kras(G12D) immortalized mouse embryonic fibroblasts (MEFs) to search for genes that wh

214 rst genome-scale map of murine NADs in mouse embryonic fibroblasts (MEFs) via deep sequencing of chro

215 h1(-/-)p53(-/-) lymphomas and derived murine embryonic fibroblasts (MEFs) were both more sensitive to

216 tious EBOV derived from SOCS3 knockout mouse embryonic fibroblasts (MEFs) were significantly reduced

217 Hsp70(-/-) murine embryonic fibroblasts (MEFs) were transformed by E1A/Ras

218 ration, and ECM remodeling of primary murine embryonic fibroblasts (MEFs) with cre/loxP-mediated vinc

219 ibroblasts lacking Atg16l1 (ATG16L1 KO mouse embryonic fibroblasts (MEFs)), an essential autophagy ge

220 es for 176 miRNAs in contact-inhibited mouse embryonic fibroblasts (MEFs), 182 miRNAs in dividing MEF

221 mouse bone marrow-derived macrophages, mouse embryonic fibroblasts (MEFs), and human HeLa cells upon

222 d in Ras(V12)-expressing p19(Arf) null mouse embryonic fibroblasts (MEFs), and overall Egr DNA-bindin

223 e and histone methylation occupancy in mouse embryonic fibroblasts (MEFs), induced pluripotent stem c

224 In eEF2K(-/-) mouse embryonic fibroblasts (MEFs), inhibition of HSP90 by its

225 In mouse embryonic fibroblasts (MEFs), inhibition of mitochondria

226 -2 can be cell surface-biotinylated on mouse embryonic fibroblasts (mEFs), revealing that endogenous

227 In mouse embryonic fibroblasts (MEFs), Sirt6 knockout (KO) increa

228 Similarly, in Kif3a null mouse embryonic fibroblasts (MEFs), the overall TonEBP-depende

229 Using knockout mouse embryonic fibroblasts (MEFs), we demonstrate that cyclin

230 oxidative stress-induced senescence of mouse embryonic fibroblasts (MEFs), whereas overexpression of

231 in p53 (-/-) and INK4a (-/-)/Arf (-/-) mouse embryonic fibroblasts (MEFs), which failed to inhibit ce

232 -Schlemm's canal endothelial cells and mouse embryonic fibroblasts (MEFs)-using four different probe

233 ripotent stem cells in comparison with mouse embryonic fibroblasts (MEFs).

234 g a SILAC approach, of PDGF-stimulated mouse embryonic fibroblasts (MEFs).

235 ltransferase for PP2A, PP4, and PP6 in mouse embryonic fibroblasts (MEFs).

236 cell lines, ex vivo tumor tissue, and mouse embryonic fibroblasts (MEFs).

237 ng an inducible knockout (KO) model of mouse embryonic fibroblasts (MEFs).

238 nd cell proliferation in Ada3-deleted murine embryonic fibroblasts (MEFs).

239 epithelial breast cells (MCF10A), and mouse embryonic fibroblasts (MEFs).

240 nd DNA damage checkpoint activation in mouse embryonic fibroblasts (MEFs).

241 tress responses, within WT or PERK -/- Mouse Embryonic Fibroblasts (MEFs).

242 well as in eEF2K-knockout (eEF2K(-/-)) mouse embryonic fibroblasts (MEFs).

243 n initiation factor 2alpha (eIF2alpha) mouse embryonic fibroblasts (MEFs); moreover, ECD mRNA levels

244 cell lines (A20.2J, CH12.LX, HAP1, and mouse embryonic fibroblasts [MEFs]) reconstituted with wild-ty

245 n mouse, non-cancerous, primary cells (mouse embryonic fibroblasts, MEFs), to assess different behavi

246 In a mouse embryonic fibroblast model, Drp1 C452F cells exhibited a

247 e energy transfer; 3) in MPC1 depleted mouse embryonic fibroblasts, MPC1L rescues the loss of pyruvat

248 found that the p53 protein in naked mole-rat embryonic fibroblasts (NEFs) exhibits a half-life more t

249 opy were performed in prkar1 knock-out mouse embryonic fibroblasts, neonatal myocytes, or adult LV my

250 Using mouse embryonic fibroblast nuclei with normal or reduced DNA m

251 Murine embryonic fibroblasts null for the UPR-associated transc

252 Embryonic fibroblasts obtained from Stonin1-deficient mi

253 man glioblastoma cells but not that of mouse embryonic fibroblasts or neonatal astrocytes.

254 Furthermore, genetic knockout (in murine embryonic fibroblasts) or siRNA knockdown (in BJ fibrobl

255 ly, we show that in kindlin-2 knockout mouse embryonic fibroblasts, overactivation of Ras, Akt, and S

256 Primary mouse embryonic fibroblasts (pMEFs) expressing caveolin 1 (Cav

257 Plk1 overexpression in mouse embryonic fibroblasts prepared from the transgenic mice

258 CYLD forms were expressed in mouse embryonic fibroblasts, primary T cells, and HEK293T cell

259 of AMPK and the use of AMPKalpha(-/-) mouse embryonic fibroblasts provided further evidence that AMP

260 ption, and decreased ATP production in mouse embryonic fibroblasts, providing insights into the cellu

261 nical autophagy: both WT and Atg5(-/-) mouse embryonic fibroblasts responded similarly.

262 wn of any or all tropomyosin isoforms in rat embryonic fibroblasts resulted in longer and more numero

263 ic ablation of MPC1 in hepatocytes and mouse embryonic fibroblasts resulted in reduced resting matrix

264 Deletion of USP9X in mouse embryonic fibroblasts resulted in significant downregula

265 However, paradoxically loss of LKB1 in mouse embryonic fibroblast results in resistance to oncogene-i

266 , alone or in combination with Trf2 in mouse embryonic fibroblasts results in increased telomere fusi

267 Transcriptome analysis using mouse embryonic fibroblasts revealed deregulation in the trans

268 Rb1-deficient mouse embryonic fibroblasts showed increased levels of Ogt and

269 of ID8 mouse ovarian tumor cells with mouse embryonic fibroblasts showed that CD73 expression in fib

270 e bone marrow-derived macrophages and murine embryonic fibroblasts stimulated with their cognate grow

271 ng decrease seen in cultured Tsc2(-/-) mouse embryonic fibroblasts, suggesting one mechanism through

272 ersist within and exit from cultured chicken embryonic fibroblasts, than the reference virulent (R_lo

273 s are abrogated in lamin A/C-deficient mouse embryonic fibroblasts that recapitulate the defective nu

274 s Ucp1 expression in undifferentiated murine embryonic fibroblasts, that this induction depends on ME

275 In contrast, in mouse embryonic fibroblasts the coding segment is depleted of

276 responses of embryonic stem cells and mouse embryonic fibroblasts to amber codon suppression.

277 We demonstrate that adaptation of mouse embryonic fibroblasts to cell culture results in a rapid

278 d Myt1l genes (BAM factors) to convert mouse embryonic fibroblasts to induced neuronal cells.

279 s to dissect direct reprogramming from mouse embryonic fibroblasts to induced neuronal cells.

280 ulting knock-out animals, we also used mouse embryonic fibroblasts to investigate the associated sign

281 Gamitrinib strongly sensitizes primary mouse embryonic fibroblasts to mPT and permeability transition

282 al changes during the reprogramming of mouse embryonic fibroblasts to pluripotent stem cells.

283 re, we use wild-type and vimentin-null mouse embryonic fibroblasts to show that VIFs regulate nuclear

284 Here, we take advantage of mouse embryonic fibroblasts transformed by oncogenic Dbl, whic

285 mor cell lines, mouse lung tumors, and mouse embryonic fibroblasts undergoing RAS-induced senescence.

286 ion of iNOS decreases cell survival in mouse embryonic fibroblasts via mechanisms involving nitric ox

287 Using knockout mouse embryonic fibroblasts we show that Miro1 and Miro2 are r

288 Using mouse embryonic fibroblasts, we genetically dissected the role

289 For endogenous beta-actin genes in mouse embryonic fibroblasts, we observe that short-lived (~8 s

290 Mitochondria in C452F mouse embryonic fibroblasts were depolarized and had reduced c

291 52A NKAP did restore proliferation in murine embryonic fibroblasts when endogenous NKAP expression wa

292 ated in aging, blocked iN cell conversion of embryonic fibroblasts, whereas knockout or knockdown of

293 d recycling of alpha5beta1-integrin in mouse embryonic fibroblasts, which enables persistent fibrobla

294 e examined the Hh signaling pathway in mouse embryonic fibroblasts, which readily responds to the Hh

295 The use of Ada3(FL/FL) mouse embryonic fibroblasts with deletion of Ada3 using adenov

296 Mouse embryonic fibroblasts with genetic ablations of TSC2 or

297 Mouse embryonic fibroblasts with Ptpn11 GOF mutations show a c

298 We used primary Ercc1 (-/-) murine embryonic fibroblasts with reduced DNA repair capacity,

299 tol (3,4,5)-trisphosphate (PIP3), from mouse embryonic fibroblasts with serum stimulation.

300 Finally, we treated Mecp2(R255X) embryonic fibroblasts with the nonsense mutation suppres