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1 ctional interaction between BAP1 and PRC2 in embryonic stem cells.
2 and mediates its recruitment to chromatin in embryonic stem cells.
3 demethylation rates at 860,404 CpGs in mouse embryonic stem cells.
4 targeted TagRFP to the Myom2 locus in mouse embryonic stem cells.
5 tering and transcription activation in mouse embryonic stem cells.
6 some in preimplantation mouse embryos and in embryonic stem cells.
7 modeling to analyze Repli-BS data from human embryonic stem cells.
8 s gate exit from naive pluripotency of mouse embryonic stem cells.
9 HDR in multiple human cell types, including embryonic stem cells.
10 intrinsically covarying gene pairs in mouse embryonic stem cells.
11 on tRNA modifications change codon usage in embryonic stem cells.
12 constructs using neurons derived from human embryonic stem cells.
13 regulation of the totipotent state in mouse embryonic stem cells.
14 the proliferation and the survival of mouse embryonic stem cells.
15 data generated from S. cerevisiae and mouse embryonic stem cells.
16 es in silencing repetitive elements in mouse embryonic stem cells.
17 envelope and plasma membrane fluctuations in embryonic stem cells.
18 mmalian stem cell types, such as pluripotent embryonic stem cells.
19 -joining maintains genome stability of human embryonic stem cells.
20 s to single cell clusters and differentiated embryonic stem cells.
21 ls of signalling pathway components in mouse Embryonic Stem Cells.
22 sine levels are highest in human pluripotent embryonic stem cells.
23 E ablates macrophage development from murine embryonic stem cells.
24 y affects gene expression in trophoblast and embryonic stem cells.
25 potency exit and germ layer specification of embryonic stem cells.
26 aptic function in neurons derived from human embryonic stem cells.
27 controlling chromatin accessibility of mouse embryonic stem cells.
28 e maintenance and genomic stability of mouse embryonic stem cells.
29 n MLL2-dependent gene as a reporter in mouse embryonic stem cells.
30 hromatin at developmental gene loci in mouse embryonic stem cells.
31 iciency of homology-directed repair (HDR) in embryonic stem cells.
32 ive CME is essential for the pluripotency of embryonic stem cells.
33 e cytoplasm of neurons derived from human HD embryonic stem cells.
34 d for optimal maintenance of pluripotency in embryonic stem cells.
35 tionally complement the loss of Jpx in mouse embryonic stem cells.
38 g efficiencies were low (<=6%), FA corrected embryonic stem cells acquired a strong proliferative adv
39 al cells and pericytes that are induced from embryonic stem cells also hinders these signaling cascad
40 cal interaction between TET1 and NANOG using embryonic stem cells and bacterial expression systems.
42 C) is exclusively expressed in the placenta, embryonic stem cells and certain cancers however, its ro
44 ineage trees of human cancer cells and mouse embryonic stem cells and develop a statistical framework
45 KDM6A is important for differentiation of embryonic stem cells and development of various tissues.
46 es of heterozygous and homozygous Chd8 mouse embryonic stem cells and differentiated neural progenito
47 ll type-specific accessibility between mouse embryonic stem cells and embryonic stem cell-derived def
48 ers at the endogenous Sox2 and Mir290 SEs in embryonic stem cells and found that the allelic DNA meth
49 related with the pluripotency grade of mouse embryonic stem cells and human induced pluripotent stem
52 DNA demethylase TET1 is highly expressed in embryonic stem cells and is important both for lineage c
53 rectly predicted early data point sources as embryonic stem cells and late data point sources as hear
55 ousands of individual regulatory elements in embryonic stem cells and measure cis and trans effects b
56 ing cells by stably expressing eCRs in mouse embryonic stem cells and measuring their subnuclear loca
58 , DNMT3A, DNMT3A/3B and DNMT1 knockout human embryonic stem cells and observed a widespread increase
60 rmal cells from mouse and human Pax3-induced embryonic stem cells and Pax3-null embryonic day (E)9.5
61 hat SPOP suppresses stem cell traits of both embryonic stem cells and PrCa cells through promoting Na
62 hole-genome mapping of 5mC and 5hmC in mouse embryonic stem cells and show that, compared with bisulf
63 principle, we applied this strategy to mouse embryonic stem cells and successfully captured the expre
64 human colon carcinoma line HCT116, and mouse embryonic stem cells and their neural progenitor derivat
65 o sequence difficult-to-map regions in mouse embryonic stem cells and to identify distinct methylatio
66 me-wide RNAi screen in BRCA2-deficient mouse embryonic stem cells and validation in KB2P1.21 mouse ma
67 reased retinoic acid signaling in both human embryonic stem cells and zebrafish mutant models, as wel
68 ith the use of adult renal progenitor cells, embryonic stem cells, and induced pluripotent stem cells
69 en characterized in certain cancerous cells, embryonic stem cells, and other rapidly proliferative ce
70 ells, YIPF5 knockout and mutation knockin in embryonic stem cells, and patient-derived induced plurip
72 me integrity, maintenance of pluripotency of embryonic stem cells, antibody-gene diversification, coo
76 ell fate decisions during development and in embryonic stem cells by maintaining pluripotency or by r
77 rmined that Sox2 directly binds RNA in mouse embryonic stem cells by UV-cross-linked immunoprecipitat
81 3K9me3)-marked heterochromatin is reduced in embryonic stem cells compared to differentiated cells.
83 and found that the organoids developed from embryonic stem cells contained a diverse array of glial
84 seq is sensitive enough to distinguish mouse embryonic stem cells cultured under different conditions
87 e neural network previously trained in mouse embryonic stem cell cultures (InDelphi-mESC) is able to
90 we investigate chromatin boundaries in mouse embryonic stem cells, defined by the regions with decrea
91 The membrane fraction from MYL4-/- human embryonic stem cell derived atrial cells demonstrated in
94 n of neonatal mouse cardiomyocytes and human embryonic stem cell-derived cardiomyocytes are considera
96 ssessed in isolated cardiomyocytes and human embryonic stem cell-derived cardiomyocytes, and function
98 ility between mouse embryonic stem cells and embryonic stem cell-derived definitive endoderm cells, s
100 lity and sensitivity of this method in mouse embryonic stem cells, developing embryos, adult tissues,
102 ass cytometry time course dataset from mouse embryonic stem cells differentiating into the three germ
103 ed several TFs across a time course of human embryonic stem cell differentiation and studied their in
104 ng literature and new experimental data from embryonic stem cell differentiation reporter assays.
105 ed to neurons transdifferentiated from human embryonic stem cells, directly increased dendritic arbor
106 ted YY1 binding sites were hypomethylated in embryonic stem cells, during neurodifferentiation, and i
109 ) signalling drives differentiation of mouse embryonic stem cells (ES cells) and pre-implantation emb
111 tenance of distinct chromatin domains during embryonic stem cell (ESC) differentiation are crucial fo
113 ws: maternal reprogramming at fertilization, embryonic stem cell (ESC) differentiation, and the conti
115 developmental pathways and study effects on embryonic stem cell (ESC) germ layer specification and m
116 he RNA-associated protein Srrt/Ars2 sustains embryonic stem cell (ESC) identity by preventing prematu
117 progenitor cell (NPC) development from mouse embryonic stem cell (ESC) lines deficient for XRCC4 plus
123 escribe the development and validation of an embryonic stem cell (ESC)-GEMM platform for rapid modeli
124 cture defined for maintenance of naive state embryonic stem cells (ESC) also explains transcription f
126 nd efficient protocol to differentiate mouse embryonic stem cells (ESC) to SpMNs and CrMNs, we now re
127 ranscriptional factor for the maintenance of embryonic stem cells (ESCs) and cancer stem cells (CSCs)
131 rved in virtually all cell types, except for embryonic stem cells (ESCs) and oocytes which are intrin
132 ive screening in lineage-related mouse naive embryonic stem cells (ESCs) and primed epiblast stem cel
133 roblems inherent in the use of controversial embryonic stem cells (ESCs) and somehow problematic indu
134 generated combinations of Tet knockout (KO) embryonic stem cells (ESCs) and systematically measured
136 h POLR3G expression being highly enriched in embryonic stem cells (ESCs) and tumor cells relative to
138 erturbed DNA modification landscape in mouse embryonic stem cells (ESCs) carrying a double knockout (
139 anscription elongation-associated factors in embryonic stem cells (ESCs) compared to somatic cells.
143 .3 and showed that the K4A mutation in mouse embryonic stem cells (ESCs) impaired differentiation and
144 D carriers via injection of mdx (murine DMD) embryonic stem cells (ESCs) into wild-type (WT) blastocy
146 gene regulatory network (GRN) of naive mouse embryonic stem cells (ESCs) must be reconfigured to enab
148 n vitro NMP populations produced either from embryonic stem cells (ESCs) or epiblast stem cells (EpiS
151 ion between 'serum' and '2i' states of mouse embryonic stem cells (ESCs) takes place with minimal enh
152 response to replication stress (RS) in mouse embryonic stem cells (ESCs) that induces genes expressed
153 we use a CRISPR mutagenesis screen in mouse embryonic stem cells (ESCs) to identify unexpected roles
154 ting forebrain structures in vivo from mouse embryonic stem cells (ESCs) via neural blastocyst comple
159 f the most highly transcribed genes in mouse embryonic stem cells (ESCs), by recruiting the transcrip
160 c acid (RA) induces rapid differentiation of embryonic stem cells (ESCs), partly by activating expres
161 can be partially recapitulated by combining embryonic stem cells (ESCs), trophoblast stem cells (TS)
163 een shape, mechanics, and fate, we use mouse embryonic stem cells (ESCs), which change shape as they
164 on neuronal differentiation of normal mouse embryonic stem cells (ESCs), with outcomes being compare
174 In the absence of Vimentin, pluripotent embryonic stem cells fail to differentiate properly, wit
175 ys reveal that Dppa2/4 double knockout mouse embryonic stem cells fail to exit pluripotency and diffe
176 BAP1 inactivation causes apoptosis in mouse embryonic stem cells, fibroblasts, liver, and pancreatic
177 a genome editing at two nucleotides in human embryonic stem cells, followed by differentiation into a
179 ular properties, and we also find that mouse embryonic stem cells have a global translation speed of
180 ng of PcG proteins to ectopic sites in mouse embryonic stem cells, here we show that PRC1 can trigger
182 entiation and proliferation markers in human embryonic stem cell (hESC)-derived beta-cells and human
183 ntify drugs that reduce ACE2 levels in human embryonic stem cell (hESC)-derived cardiac cells and lun
184 DA-approved chemotherapy drugs against human embryonic stem cells (hESC) in which we engineered TP53
185 Our analysis on ChIP-seq experiment in human embryonic stem cells (hESC) revealed that DNMT3B, mCA an
186 culture human cerebral organoids from human embryonic stem cells (hESC) to investigate the effect of
189 ism and cognitive function in mice and human embryonic stem cells (hESCs) expressing mutant fatty aci
190 zonation during the differentiation of human embryonic stem cells (hESCs) from endoderm toward termin
191 protocol for the derivation of mouse haploid embryonic stem cells (hESCs) from female gametes that al
192 ed genome editing to generate isogenic human embryonic stem cells (hESCs) harboring clinically releva
194 cosphingolipid (GSL) profiles in naive human embryonic stem cells (hESCs) have not been systematicall
195 ment and during the differentiation of human embryonic stem cells (HESCs) into insulin-producing cell
196 e transplanted DA neurons derived from human embryonic stem cells (hESCs) into the striatum and asses
198 used CRISPR/Cas9 to generate isogenic human embryonic stem cells (hESCs) that lack the individual pr
199 th neurogenesis and cardiogenesis from human embryonic stem cells (hESCs) through distinct mechanisms
201 we describe a method to differentiate human embryonic stem cells (hESCs) to thalamic organoids (hThO
204 itical role in regulating behaviors of human embryonic stem cells (hESCs), affecting their proliferat
205 ortical organoids (hCOs), derived from human embryonic stem cells (hESCs), provide a platform to stud
208 ffects were observed in WRN(-/-) or BLM(-/-) embryonic stem cells, however upon their differentiation
210 C2 thus plays essential roles in maintaining embryonic stem cell identity and in controlling cellular
216 engineered ureteric buds differentiated from embryonic stem cells in three-dimensional culture and gr
217 ontrasts with the profiling data of HeLa and embryonic stem cells in which distinct down-regulation o
218 Es) are shared between MBNL1-low cancers and embryonic stem cells including a MAP2K7Deltaexon2 splice
219 are often described as sharing features with embryonic stem cells, including the expression of OCT4A,
220 Mettl3 or the nuclear reader Ythdc1 in mouse embryonic stem cells increases chromatin accessibility a
222 ddressed this by injecting labeled wild-type embryonic stem cells into blastocysts derived from lipod
223 ges in the O-GlcNAc proteome, while in mouse embryonic stem cells it leads to loss of O-GlcNAcase and
224 alter gene transcription in hepatocytes and embryonic stem cells lacking both REV-ERBalpha and -beta
225 in mammals, we used CRISPR to generate mouse embryonic stem cells lacking one or both of the two muri
228 we show that the mutation rate in two human embryonic stem cell lines derived and banked for clinica
229 precedented temporal resolution in two human embryonic stem cell lines, human colon carcinoma line HC
231 cing assays, patients' RNA analyses, a mouse embryonic stem cell (mESC) complementation assay and ret
232 Channelrhodopsin-2 (ChR2) transfected mouse embryonic stem cell (mESC) derived motor neurons to expl
233 , using loss-of-function approaches in mouse embryonic stem cells (mESCs) and deep sequencing of rRNA
234 d sequenced TET2-crosslinked RNAs from mouse embryonic stem cells (mESCs) and found a high enrichment
235 applied CAP-C to formaldehyde prefixed mouse embryonic stem cells (mESCs) and investigated loop domai
239 data from a retinoic acid (RA)-induced mouse embryonic stem cells (mESCs) differentiation experiment.
242 ere significantly decreased in Tet2 KO mouse embryonic stem cells (mESCs) in comparison with wild-typ
243 in Xenopus embryos and differentiating mouse embryonic stem cells (mESCs) leads to a surprisingly res
244 2) We report that absence of Mettl5 in mouse embryonic stem cells (mESCs) results in a decrease in gl
245 in Dnmt3a/3b/3l triple-knockout (TKO) mouse embryonic stem cells (mESCs) reveal that Dnmt3b3 prefers
246 ead to differentiation instability in murine embryonic stem cells (mESCs) via DNA hypomethylation at
250 t for PRDM10 in pre-implantation embryos and embryonic stem cells (mESCs), where loss of PRDM10 resul
257 strong core-periphery mesoscale structure in embryonic stem cells, neural progenitor cells, and corti
258 Here, we map circRNA inventories of mouse embryonic stem cells, neuronal progenitor cells and diff
259 e transplantation of DA neurons derived from embryonic stem cells or induced pluripotent stem cells (
261 y monocytes, cerebral organoids derived from embryonic stem cells, organotypic mouse cerebellar slice
265 erexpression of NEUROG2 and NEUROG1 in human embryonic stem cells produces a network of excitatory an
268 ferentiation, a proportion of Whsc1-depleted embryonic stem cells remain entrapped in a pluripotent s
270 of whole transcriptome data from nup155(+/-) embryonic stem cells revealed changes in a variety of no
271 CRISPR interference of RLTR13D6 elements in embryonic stem cells revealed that only a minority play
272 Moreover, endogenous tagging of Nanog in embryonic stem cells reveals that ERK inhibition promote
274 periments in Dnmt3a/3b double knockout mouse embryonic stem cells show that the corresponding Arg878H
276 taining nucleosomes at desired loci in mouse embryonic stem cells so that their fate after DNA replic
279 we develop a conditional mutation system in embryonic stem cells that completely removes PRC1 cataly
280 truloids are three-dimensional aggregates of embryonic stem cells that display key features of mammal
281 iation of insulin-producing cells from human embryonic stem cells, the generation of mature functiona
283 te differentiation stages derived from human embryonic stem cells to construct different types of RT
284 of growth factors and drugs to induce mouse embryonic stem cells to differentiate into ureteric bud
285 Using in vitro directed differentiation of embryonic stem cells to motor neurons, we show that the
287 al work describing how the innate ability of embryonic stem cells to self-organize into layers and gr
288 middle-down analyses of histones from mouse embryonic stem cells via online chromatography to fracti
290 n during neuronal lineage induction of human embryonic stem cells we identified miR-934, a primate-sp
292 methods to data from S. cerevisiae and mouse embryonic stem cells, we find that the extracted rates r
295 nal repression, and at CAG trinucleotides in embryonic stem cells, where it positively correlates wit
296 pagation and long-term self-renewal of human embryonic stem cells while preserving their pluripotency
298 bine induced neurons (iNeurons) derived from embryonic stem cells with quantitative proteomics to rev
299 and differentiated cells obtained from human embryonic stem cells with relatively long telomeres have
300 ndogenous retroviral (ERV) elements in mouse embryonic stem cells, with gain of chromatin accessibili