ライフサイエンスコーパス: embryonically

1 ionship to axonal guidance mechanisms active embryonically.

2 taining differentiated intestinal cells post-embryonically.

3 and coagulopathy, while hemizygous males die embryonically.

4 origins, derived from adult bone marrow and embryonically.

5 dult muscle progenitor (AMP) cells set-aside embryonically.

6 mily encoded by animal genomes and expressed embryonically.

7 d defects, suggesting that SOST may function embryonically.

8 genes that are normally expressed only post-embryonically.

9 ouse genetic fate-mapping analyses show that embryonically, a c-Kit(+) population contributes to olfa

10 tested nonsense mutations in wg and in other embryonically acting genes and found that different stop

11 tatory cerebellar output neurons are ablated embryonically and demonstrate that the main requirement

12 miR-409-3p and miR-409-5p located within the embryonically and developmentally regulated DLK1-DIO3 (d

13 Olfactory sensory neurons (OSNs) form embryonically and mature perinatally, innervating glomer

14 ve pituitary stem cells (PSCs) are specified embryonically and persist throughout life, giving rise t

15 ous deletion mutant affected Pdx1 expression embryonically and postnatally.

16 roventral hypothalamic neuroepithelium, both embryonically and postnatally.

17 d on the myogenic determinants Pax3 and Pax7 embryonically, and Pax7 alone perinatally.

18 Although MUA-6/IFA-2 is expressed embryonically, and plays an essential postembryonic role

19 r stage can Epo expression be detected intra-embryonically, and the onset of Epo expression correlate

20 about how this axis can be established post-embryonically, as occurs in budding animals.

21 daries, and STM controls CUC expression post-embryonically at organ boundary domains.

22 zygous for the T424GfsX48 allele were lethal embryonically, attenuated PNKP levels (akin to MCSZ) sho

23 ythmic motor patterns and movements are seen embryonically, before they are needed for behavior; rece

24 Mice lacking endothelial p120 died embryonically beginning at embryonic day 11.5.

25 The 81 embryonically born body wall muscle cells in C. elegans

26 WI/SNF mutants that arrest their development embryonically but exhibit near wild-type levels of expre

27 DIMM expression began embryonically but persisted in adults.

28 rograde staining at all stages, is also born embryonically but remains developmentally arrested until

29 velopment and renewal, repressing taste fate embryonically, but promoting TRC differentiation in adul

30 The gene is transcribed embryonically, but unlike the maternally expressed Droso

31 throughout the lingual epithelium, beginning embryonically, chorda tympani fibers are misdirected and

32 Each tissue has its own composition of embryonically derived and adult-derived macrophages, but

33 unable to replicate the distinct identity of embryonically derived BAMs and microglia.

34 r and the FGF receptor, is vital to preserve embryonically derived circuit architecture during postde

35 aic of medial and adventitial cells that are embryonically derived from either the second heart field

36 We identified two distinct populations among embryonically derived Kupffer cells (KCs) sharing a core

37 l-like factor 2 (KLF2) in the development of embryonically derived large cavity macrophages (LCMs) in

38 ed at +164-kb that was selectively active in embryonically derived lineages, but not HSC-derived ones

39 e genes are also expressed in another set of embryonically derived mechanosensory neurons, the FLP ne

40 system and have implications for the use of embryonically derived microglial progenitors for the tre

41 Thus, we have identified a pool of embryonically derived radial glia-like cells present in

42 st was not required for the formation of the embryonically derived striated muscles.

43 macrophages are transient, reside alongside embryonically derived T cell immunoglobulin and mucin do

44 d more potent roles in antigen presentation, embryonically derived TAMs exhibited a pro-fibrotic tran

45 s, they acquire a transcriptome identical to embryonically derived tissue-resident Mphis.

46 lly and functionally distinct cell lineages: embryonically derived triggering receptor expressed on m

47 macrophage lineages in the lung, comprising embryonically derived, tissue-resident alveolar macropha

48 tablish similarities and differences between embryonically derived- and larval lymph gland hemocytes.

49 l factors in regulating the morphogenesis of embryonically-derived placental tissues.

50 Unlike embryonically developing cerebral eyes that are function

51 starts with the reciprocal induction of two embryonically distinct analages, metanephric mesenchyme

52 e guinea-pig oesophagus are derived from two embryonically distinct sources: neurones situated in the

53 neurons in the adult neocortex are produced embryonically during a brief but intense period of neuro

54 When examined embryonically during the PCD period, however, these exce

55 Furthermore, the trajectory from embryonically dysregulated synaptic and cell cycle genes

56 We found that 2 embryonically enriched ECM proteins, SLIT2 and NPNT (nep

57 Post-embryonically, epigenetic signaling within neurons has b

58 Here, we address mechanisms regulating the embryonically expressed a-like globin, termed z-globin.

59 ow allele-specific interactions with the two embryonically expressed alpha-tubulins: One of the allel

60 We show here that the CoAA gene is embryonically expressed and alternatively spliced in mul

61 45 kDa protein (KIAA0005 or BZAP45) that is embryonically expressed and phylogenetically conserved.

62 diverse, and transitions from maternally to embryonically expressed elements.

63 We show that the embryonically expressed gene elt-1, which was shown prev

64 ox gene family consists of a large number of embryonically expressed genes related via the possession

65 a sites are present in the promoters of many embryonically expressed genes, but the combination of Ze

66 been generally less consistent than that of embryonically expressed genes, perhaps because the conce

67 romatin modifiers, FMRP-associated genes and embryonically expressed genes.

68 localizes at postsynaptic sites and replaces embryonically expressed GlyRalpha2 homomers.

69 ntly suppress activation by the full-length, embryonically expressed isoform.

70 Twenty-five of the forty-six embryonically expressed microRNAs show readily discernib

71 wn of DGCR8 not only inhibited expression of embryonically expressed miRNAs but also inhibited the mo

72 The results reveal a novel role for embryonically expressed neurotransmitters.

73 We have molecularly characterized two embryonically expressed odd-cognate genes, sob and bowel

74 of embryonic cuticle via a pathway involving embryonically expressed receptor kinases GASSHO1 and GAS

75 We show that >200 embryonically expressed transcription factors together d

76 expression patterns of reporters for several embryonically expressed transcription factors.

77 specific RNA interference targeting all four embryonically expressed tubulin genes singly and in all

78 Because the MBP:1-9 sequence is embryonically expressed uniquely in the context of Golli

79 ult dorsal unpaired median (DUM) group arise embryonically from a single precursor, the median neurob

80 hes, we show that arterial macrophages arise embryonically from CX3CR1(+) precursors and postnatally

81 In plants, organs are generated post-embryonically from highly organized structures known as

82 leaves, roots, flowers, etc.) continues post-embryonically from persistent stem cell populations know

83 es that are similar to the neurons born post-embryonically from the same neuroblast.

84 y glutamatergic Pet1 neurons in the MR arise embryonically from the same progenitor cell compartment-

85 The embryonically generated DD motor neurons initially inner

86 n results in defective differentiation of an embryonically generated serotonergic neuron type.

87 to 25 cardinal classes, to the predominantly embryonically generated, sex-shared nervous system, comp

88 sing C3 lacking exon 6, an isoform expressed embryonically, have muscles that resemble regenerating o

89 isolated lymphoid follicles (ILFs), but not embryonically 'imprinted' Peyer's patches.

90 ematode Caenorhabditis elegans are generated embryonically in both hermaphrodites and males but under

91 The zebrafish crestin gene is expressed embryonically in neural crest progenitors (NCPs) and spe

92 , we find that the Nkx6-2 promoter is active embryonically in neuroblasts and postnatally in oligoden

93 CeE/DA is present embryonically in neuronal precursors, some of which are

94 PBX1 is expressed embryonically in the telencephalon.

95 hed core mammalian autophagy protein that is embryonically indispensable and has been presumed to sup

96 regulated RNA binding proteins that includes embryonically lethal abnormal vision-type RNA binding pr

97 The loss of Meox2 is not embryonically lethal and a small percentage of animals s

98 However, deletion of BMP4 is early embryonically lethal and its functional role in definiti

99 Murine Inpp5e ablation is embryonically lethal and recapitulates JBTS, including n

100 PBP null mutation (PBP(-/-)) is embryonically lethal at embryonic day 11.5, suggesting t

101 in the PCP pathway; in mice, Vangl2 loss is embryonically lethal because of neural tube defects, and

102 Finally, GshF expression in mice is embryonically lethal but sustains postnatal viability wh

103 While global deletion of AIP in mice yields embryonically lethal cardiac malformations, heterozygote

104 Deletion of Ubiad1 was embryonically lethal in C57BL/6 N mice, preventing analy

105 e two different 3- to 4-cM deficiencies were embryonically lethal in heterozygous mice.

106 d in integrin activation, and its absence is embryonically lethal in mice and causes severe developme

107 in humans, whereas their genetic ablation is embryonically lethal in mice.

108 mediated knockout of the two Zak isoforms is embryonically lethal in mice.

109 d in integrin activation, and its absence is embryonically lethal in mice.

110 en with ABS, even though knock-out of POR is embryonically lethal in mice.

111 nce (P < 0.0001, Pearson chi-square test) an embryonically lethal phenotype of homozygous murine CSE1

112 Both transgenic lines rescued the embryonically lethal Pkd1(del34/del34) phenotype, demons

113 form of PC1 exits the ER and can rescue the embryonically lethal Pkd1-null mutation.

114 Crry deletion is embryonically lethal whereas DAF-deficient mice are gene

115 In mice, complete loss of ADAR1 activity is embryonically lethal(3-6), and mutations similar to thos

116 While a multi-motif mutant was embryonically lethal, a single-nucleotide Ets motif muta

117 Znf335 null mice are embryonically lethal, and conditional knockout leads to

118 o-disruption of Apob, whose germline loss is embryonically lethal, completely prevented disease throu

119 e deletion of either Pkd1 or Pkd2 in mice is embryonically lethal, conditional alleles have become in

120 Genetic knockdown of RBM15 in mouse is embryonically lethal, indicating that OTT3 cannot compen

121 se simultaneous knockout of IRP1 and IRP2 is embryonically lethal, it has not been possible to use du

122 While furin knockout is embryonically lethal, its knockout in differentiated som

123 Because germline deletion of Dhps is embryonically lethal, its role in normal postnatal cellu

124 owever, because caspase-8-deficient mice are embryonically lethal, little is known about how caspase-

125 of Fpn1 in late gestation mouse placenta is embryonically lethal, providing direct evidence for an e

126 kout of most murine AP-1 complex subunits is embryonically lethal, so the identification of human dis

127 regulator of Notch and that its deletion is embryonically lethal, we generated mice that overexpress

128 Ddx41 knockout in early erythropoiesis is embryonically lethal, while knockout in late-stage termi

129 ition approaches, as Plk1 null mutations are embryonically lethal.

130 Homozygous germ-line disruptions of S1P were embryonically lethal.

131 Homozygous Gs deficiency is embryonically lethal.

132 pecific molecular chaperone whose absence is embryonically lethal.

133 n underdeveloped compact myocardium and were embryonically lethal.

134 several of its core elements are known to be embryonically lethal.

135 In mice, biallelic loss of TBK1 is embryonically lethal.

136 omatic deletion of the CXCR4 gene in mice is embryonically lethal.

137 T2DNPar1-/- rats were embryonically lethal.

138 plete loss of this proto-oncogene in mice is embryonically lethal.

139 Deletion of either gene in mice is embryonically lethal.

140 in GVHD, as germ line Cdk5 gene deletion is embryonically lethal.

141 f a catalytically inactive version of ATM is embryonically lethal.

142 his transition, and their null mutations are embryonically lethal.

143 Germ line deletion of both c-jun alleles is embryonically lethal.

144 d, and global knockout of the Depdc5 gene is embryonically lethal.

145 exacerbates EPP and renders beta-thalassemia embryonically lethal.

146 A targeted null Napa mutation is embryonically lethal.

147 uire the expression of amacrine cell markers embryonically, likely representing nascent cholinergic a

148 Mouse PL neurons are born embryonically, not from postnatal neurogenesis, despite

149 -beyond its fundamental derivation as either embryonically or bone marrow-derived, but rather inclusi

150 does not supply cells to taste buds, either embryonically or postnatally, thus ruling out a mesenchy

151 biosynthesis in these neurons in mice either embryonically or postnatally.

152 ly reduced levels of all three CLCs and died embryonically or shortly after birth.

153 al amygdala (MeA) cells originating from two embryonically parcellated developmental lineages have di

154 cated only in cell divisions that occur post-embryonically, primarily in terminal neuronal lineages.

155 The embryonically produced class III Kenyon cells form a sep

156 e hippocampus generates both the LL-NSCs and embryonically produced granule neurons.

157 M to reveal the adult morphology of the post embryonically produced neurons in the thoracic neuromere

158 The late larval brain consists of embryonically produced primary neurons forming a deep co

159 Embryonically, proliferation of radial glial cells (RGC)

160 specific de novo methylation at hundreds of embryonically protected CpG island promoters, particular

161 Transcription factors (TFs) that embryonically regulate pallial regionalization are expre

162 constrains tumours in part by repressing the embryonically restricted chromatin regulator Hmga2.

163 Post-embryonically, retn RNAs are expressed in a limited set

164 tion, which suggests that it is a marker for embryonically specified, long-lived germline progenitors

165 Mouse models which have embryonically targeted torsinA have failed to recapitula

166 he nervous system in C. elegans is generated embryonically, the role of REF-1 in regulating these neu

167 t is hidden belowground, which develops post-embryonically through the formation of lateral roots.

168 Plants produce new organs post-embryonically throughout their entire life cycle.

169 These results indicate that embryonically transcribed gene products are required for

170 In the absence of PIE-1, embryonically transcribed RNAs are detected in both soma

171 show that after each asymmetrical division, embryonically transcribed RNAs are detected in somatic,

172 vealed preferential interconnectivity within embryonically TRAPed piriform neurons and their enhanced

173 els recordings in neonates demonstrated that embryonically TRAPed piriform neurons exhibit broad func

174 Thus, embryonically TRAPed piriform neurons represent an inter

175 e and highly penetrant single disruptions of embryonically upregulated FMRP targets ("single-hit etio

176 ine song systems, zebra finches were treated embryonically with an inhibitor of estrogen synthesis.