ライフサイエンスコーパス: emergent

1 Multiple tissue samples were obtained during emergent abdominal surgery in 4 patients with coronaviru

2 tabolic activity and requirements, including emergent activities in and dependences on fatty acid met

3 without any clinically significant treatment emergent adverse effects.

4 At least 1 treatment-emergent adverse event occurred in 86%, 92%, and 87% of

5 The most frequent treatment-emergent adverse event of grade 3 or higher was anaemia

6 The most frequent grade >= 3 treatment-emergent adverse event was anemia (25.2%; 29 of 115 pati

7 kizumab Q2W group had at least one treatment-emergent adverse event.

8 ebo group had at least one serious treatment-emergent adverse event.

9 Treatment-emergent adverse events (AEs) were mostly grade 1 or 2.

10 ts (85%) experienced >=1 grade 3/4 treatment-emergent adverse events (AEs), most commonly neutropenia

11 (79.3%) patients on lacosamide had treatment-emergent adverse events (placebo 79/121 (65.3%)), most c

12 The most common treatment-emergent adverse events (TEAEs) across all groups were n

13 n the ASP4345 group experienced 73 treatment-emergent adverse events (TEAEs) and 34 TEAEs were report

14 h a patient experienced grade >= 3 treatment-emergent adverse events (TEAEs) or the mean duration in

15 The most common grade 3-4 treatment-emergent adverse events (TEAEs) were anaemia (grade 3, 2

16 ent end point was the incidence of treatment-emergent adverse events (TEAEs).

17 Treatment-related treatment-emergent adverse events during the 12-month study were r

18 Serious treatment-emergent adverse events in more than one patient were pn

19 The most frequent (> 30%) treatment-emergent adverse events in patients with GIST receiving

20 The most common treatment-emergent adverse events in the ixekizumab groups were na

21 2%) grade 3 or 4 treatment-related treatment-emergent adverse events in the ripretinib group (n=85) i

22 The most common treatment-emergent adverse events included infections with grades

23 No serious adverse events or treatment-emergent adverse events leading to discontinuation were

24 Serious treatment-emergent adverse events occurred in 23 (29%) of 78 patie

25 Treatment-emergent adverse events occurred in 277 (84%) of 331 par

26 Grade 3-4 treatment-emergent adverse events occurred in 34 (44%) of 78 patie

27 Treatment-emergent adverse events occurred in 76 (70%) of 108 pati

28 Serious treatment-emergent adverse events occurred in 93 (48%) patients in

29 Serious treatment-emergent adverse events occurred in nine patients, eight

30 No drug-related serious treatment-emergent adverse events occurred.

31 No grade 5 treatment-emergent adverse events occurred; 5 patients died, inclu

32 The most common treatment-emergent adverse events of grade 3 or worse were neutrop

33 Evolocumab was well tolerated, and treatment-emergent adverse events patient incidence was similar am

34 The most frequent treatment-emergent adverse events that occurred more with berotral

35 The incidence of treatment-emergent adverse events was 35%, 38%, 38%, and 34% in su

36 The incidence of treatment-emergent adverse events was similar between treatment ar

37 he proportion of participants with treatment-emergent adverse events was similar with fidaxomicin (73

38 Treatment-emergent adverse events were also examined.

39 2%) grade 3 or 4 treatment-related treatment-emergent adverse events were anaemia (three [7%]), fatig

40 Treatment emergent adverse events were balanced across treatment g

41 Treatment-emergent adverse events were consistent with DARA SC in

42 The most common treatment-emergent adverse events were diarrhoea and nausea (in ni

43 Most common grade 3-4 treatment-emergent adverse events were indirect hyperbilirubinaemi

44 Treatment-emergent adverse events were most frequent in the highes

45 The most common grade 3 or worse treatment-emergent adverse events were neutropenia (35 [18%] of 19

46 Seventy-five treatment-emergent adverse events were observed in 27 participants

47 Treatment-emergent adverse events were reported in 122 (53%) of 23

48 Serious treatment-emergent adverse events were reported in 83 (22%) patien

49 Types and number of treatment-emergent adverse events were similar between galcanezuma

50 Other treatment-emergent adverse events were transient nausea (in 15 [28

51 me measures were safety, including treatment-emergent adverse events, and efficacy, including corneal

52 Overall, 136 patients experienced treatment-emergent adverse events, including six serious adverse e

53 The most common grade 3 or worse treatment-emergent adverse events, reported in patients who had at

54 therapy had acute grade 3 or worse treatment-emergent adverse events, which accorded with frequently

55 in the bimekizumab groups reported treatment-emergent adverse events.

56 Safety assessments included treatment-emergent adverse events.

57 one dose of study drug in terms of treatment-emergent adverse events.

58 int was the number and severity of treatment-emergent adverse events.

59 mary endpoint was the incidence of treatment-emergent adverse events; secondary endpoints were change

60 Primary outcome measures were treatment-emergent AE (TEAE), AESI, SAE, and ADR occurrences.

61 Treatment-emergent AEs were experienced by 32.8% (106/323), 39.8%

62 Emergent and imminent emergent cases should mostly proce

63 re, we show that epistasis for fitness is an emergent and predictable property of nonlinear selective

64 This study reviewed and characterized each emergent and/or urgent procedure performed during April

65 aquatic environment to the riparian zone via emergent aquatic insects.

66 udy the effects of bacterial antigens on the emergent B-1 B cell clonal repertoire.

67 ss-neutralization to a highly homologous pre-emergent bat coronavirus, WIV1-CoV, which has not yet cr

68 potential is a cell-intrinsic property or an emergent behavior coming from global tissue dynamics and

69 ncentrations of regulators and influence the emergent behavior of mitotic waves.

70 ions toward functional investigations of the emergent behavior that govern tumor-immune responses.

71 chanisms and complex interactions underlying emergent behaviors.

72 e and can lead to non-reciprocal and complex emergent behaviour in multibody systems.

73 , and introduces a complementary modality of emergent behaviour-which we refer to as causal decouplin

74 for their ability to hydrolyze penicillins, emergent beta-lactamases can now confer resistance to ot

75 atriuretic peptide and troponin T, and newly emergent biomarkers, angiopoietin-2, thrombospondin-2, l

76 ,B,C,D,E,F,G)-(Equine) (BAT) manufactured by Emergent BioSolutions Canada Inc is an equine-derived he

77 , whereas patients with septic shock warrant emergent broad-spectrum antibiotics.

78 These novel approaches support an emergent but purposeful transition and suggest a clear p

79 ticity impact this class of proteins and how emergent cancer-associated properties may offer opportun

80 Referrals for emergent cardiothoracic surgery were rare regardless of

81 Emergent and imminent emergent cases should mostly proceed unless resources ar

82 pin substrates into the system, CDN-dictated emergent catalytic transformations are accomplished.

83 , coronavirus disease 2019 (COVID-19), is an emergent cause of mortality worldwide.

84 This allows us to study an emergent cellular hedging strategy that maximizes the ex

85 Now, an emergent challenge is to understand the consequences of

86 pread rapidly nationally, causing widespread emergent changes to the health system.

87 omenological approximation that captures the emergent character of stomatal behaviour.

88 have been widely employed to understand the emergent chemistry that arises from the formation of the

89 Null aggregates are an elusive, emergent class of molecular assembly categorized as spec

90 in place for urgent discussion and review of emergent clinical problems, and a system in place for ra

91 e, coupling presymptomatic OA detection with emergent clinical therapies could modify the outcome of

92 The emergent clones had acquired resistance through engageme

93 ue relate to differences in attention, drive emergent collective outcomes.

94 e for 214 patients for the primary analysis; emergent ColR organisms were detected in 22 (10.3%).

95 The COVID-19 pandemic has shown how a newly emergent communicable disease can lay considerable burde

96 opic heterogeneity has been shown to produce emergent complex behaviors such as bistability.

97 Hepatic crisis is an emergent complication affecting patients with sickle cel

98 ux disease and diabetes mellitus, as well as emergent complications including pneumomediastinum.

99 The emergent compounds were assessed for functional activity

100 ivately insured patients who present with an emergent condition.

101 We further highlight emergent connections between transcriptional control ena

102 This spatial emergent constraint allows us to halve the uncertainty i

103 ring during the study period, 1078 underwent emergent coronary angiogram (median age: 59.6 years, 78.

104 Patients undergoing emergent coronary angiogram were included.

105 e lesions who would, therefore, benefit from emergent coronary angiogram.

106 peri-procedural myocardial infarction and 1 emergent coronary bypass.

107 By describing the life cycle of the newly emergent coronavirus, SARS-CoV-2, in light of emerging d

108 SARS-CoV-2 is a newly emergent coronavirus, which has adversely impacted human

109 ith unique performance profiles suitable for emergent demands.

110 ource distributions, consumer body size, and emergent demographic risk offers key ecological insights

111 temperature regimes have been implicated in emergent disease outbreaks, making it a critical environ

112 and presents a near-real time assessment of emergent disease that can be used to guide a local inter

113 known or thought to be related to adolescent-emergent disorders, specifically depression, anxiety, an

114 ciples (differential computational capacity, emergent division of labor across pathways, experience-d

115 (across 3 years) variation in assemblages of emergent dragonflies (Anisoptera) and assessed the relat

116 Emergent dragonfly responses were associated with spatia

117 of the energizing electric field, we reveal emergent dynamic phases, ranging from a gas of spinners

118 algorithm, whose aims are to (1) predict the emergent dynamical behaviors of highly heterogeneous sys

119 -term (<10 year) warming experiments produce emergent ecosystem carbon stock temperature sensitivitie

120 Within this operational context, emergent ecosystem properties are becoming quite promisi

121 ive rise to trophic mismatches governing the emergent effects of global change.

122 in exposure and resources when inferring the emergent effects of global change.

123 erostructures have given rise to a number of emergent electronic phenomena due to the interplay betwe

124 sensitive diagnoses in medicine and requires emergent endovascular therapy to reduce morbidity and mo

125 Our findings shed light on the origin of emergent European CWD, have significant implications for

126 text in the adoption of new technologies and emergent evidence, with illustrative examples from world

127 Twenty-eight treatment-emergent F substitutions were identified.

128 the placebo group, with eight (4%) treatment-emergent fatal infections reported in the venetoclax gro

129 Our results showed that emergent features and the information content of the ent

130 Here, we show in three experiments how emergent features break this rule.

131 Observers identified targets with various emergent features consisting of a pair of adjacent chevr

132 lay uniformity judgments benefitted from the emergent features of Diamonds.

133 e we report on the surprising observation of emergent ferroelectricity in graphene-based moire hetero

134 Zika virus (ZIKV) is an emergent flavivirus initially considered a benign and se

135 use LLPS in a cellular context to implement emergent functionalities that scale their relationship f

136 in controlling the electronic structure and emergent functionality of the heterostructure, thereby p

137 Treatment-emergent grade 3-4 adverse events occurred in 59% receiv

138 Rather, the emergent groups suggest that Bowel Disorders occur on a

139 orrhage below the diaphragm and decision for emergent hemorrhage control intervention within 60 minut

140 ty in these hosts will mitigate the risks of emergent human and livestock strains.

141 The newly emergent human virus SARS-CoV-2 (severe acute respirator

142 218 patients treated with placebo; treatment-emergent hypocalcaemia occurred in 152 (7%) versus 82 (4

143 Influenza viruses harboring treatment-emergent I38F/M/N/T substitutions in the polymerase acid

144 dentifying linguistic hierarchical structure emergent in artificial neural networks and demonstrate t

145 ality corn yield prediction can help address emergent information asymmetry problems and in doing so

146 opagate to the riparian food web via aquatic emergent insects.

147 oduce the key regulators and highlight newly emergent insights into the rules that govern their actio

148 We find emergent interface-localized electronic states within th

149 who were transferred to the hybrid suite for emergent intervention between 2013 and 2017 were compare

150 The fourth patient underwent emergent laparotomy for a perforated peptic ulcer and di

151 second patient with Crohn disease underwent emergent laparotomy for a perforation in the terminal il

152 framework can be fully generalized to other emergent layered materials.

153 Moreover, our MC simulations suggest an emergent length scale for coarse-graining proteins, as w

154 entify novel electrophysiological markers of emergent literacy.

155 Emergent macrophyte species selection is critical for th

156 our mechanistic understanding of the role of emergent macrophytes on nutrient retention in aquatic en

157 nclear which defects are responsible for the emergent magnetic interfaces.

158 s as of yet no analogue of these effects for emergent magnetic monopoles.

159 an optical selection rules and for exploring emergent magneto-optical effects and spin-phonon coupled

160 Patients who underwent non-emergent, major orthopedic or abdominal surgery includin

161 playground for exotic physical phenomena and emergent many-body quantum states.

162 Cross sections are analyzed by several emergent mapping techniques.

163 ecosystem carbon stocks (TECS) in seagrass, emergent marshes, and forested tidal wetlands, occurring

164 Crystal adaptronics is an emergent materials science discipline at the intersectio

165 gest that lamin filaments arrange to form an emergent meshwork whose topology dictates the mechanical

166 t with macroscopic strain fields to generate emergent meso-scale geometries of induced fractures.

167 y of single-virus genomics, outline how this emergent method has facilitated advances in virus ecolog

168 Third, emergent modalities that convert occupancy-driven mode o

169 This emergent moire ferroelectricity may enable ultrafast, pr

170 temperature sensitivities inconsistent with emergent multi-decadal responses.

171 d asymmetric path dependence are a result of emergent nanophotonic processes at the growth interface

172 ing operando techniques, we show that in the emergent nanostructure, the endogenous nanoparticles and

173 31% (no drug-related deaths), and treatment-emergent nephrotoxicity in 10% and 56% (P = .002), respe

174 response, all-cause mortality, and treatment-emergent nephrotoxicity.

175 ed genetic and environmental perturbation on emergent network activity in the prefrontal cortex, iden

176 Additionally, SpAn infers the emergent network biology of tumor microenvironment spati

177 nal transmission and integration, as well as emergent network properties.

178 developed to characterize and interpret the emergent nonreciprocal phenomena and is later validated

179 model's inability to account for culturally emergent normativities, and point out the foundational i

180 This study characterized the delivery of emergent ophthalmic surgical care during April 2020 of t

181 with prescribed morphologies and tunable or emergent optoelectronic properties.

182 alysis of Rho regulators is key to revealing emergent organization principles of Rho signalling.

183 tudies for revealing consistent dynamics and emergent outcomes of no-till agriculture, shown to be be

184 ure of hematopoiesis is made possible by the emergent outcomes of vast, interconnected regulatory net

185 ry syndrome coronavirus 2 (SARS-CoV-2) is an emergent pathogen responsible for the coronavirus diseas

186 in vivo, in vitro, and in silico to resolve emergent pathological properties and disease mechanisms.

187 Identifying emergent patterns of coronavirus disease 2019 (COVID-19)

188 Emergent PCI of unstable lesions is associated with impr

189 Emergent PCI was performed in 478 patients (91.4% of uns

190 lat bands are a promising platform for novel emergent phases of matter at the confluence of strong co

191 hin films, and the characterization of their emergent phenomena and exotic phases.

192 st that many common vascular dynamics may be emergent phenomena generated by NO degradation by the bl

193 ew quantitative theories of what constitutes emergent phenomena have been proposed.

194 A defining feature of emergent phenomena in complex oxides is the competition

195 e themselves in various ways, giving rise to emergent phenomena that can be surprisingly rich and oft

196 delivery to sites of energy demand; however, emergent phenomena, such as mitochondrial transmembrane

197 make it an ideal system to investigate rich emergent phenomena.

198 y and electronic structure, thereby enabling emergent phenomena.

199 ggest that social identity can be seen as an emergent phenomenon and is the consequence, rather than

200 sses in adults, but less is known about this emergent phenomenon early in life.

201 confinement indicating that patterning is an emergent phenomenon that results from the many interacti

202 Emergent phenotypes associated with these genetic island

203 ich cis-regulatory element turnover generate emergent phenotypes is crucial to our understanding of a

204 ructures and control of their structures and emergent physical phenomena through epitaxial strain, la

205 ynthetic polymers enables the realization of emergent physical properties from readily available star

206 bble domains, and polar skyrmions) and their emergent physical properties in ferroelectric oxide film

207 quantum systems are promising simulators of emergent physics beyond the simulation capabilities of c

208 exuviae), which reveal information about the emergent population without the need for sacrificing liv

209 regulated transition trajectories, producing emergent population-scale models to be explored for desi

210 r decades, research is only just underway on emergent processes.

211 gher-order molecular assemblies that exhibit emergent properties and functions.

212 Alloys can offer emergent properties and new design strategies compared t

213 king components that generate these critical emergent properties are unknown.

214 rchical assembly of superatoms gives rise to emergent properties in lattices of quantum dots, p-block

215 across TLs (CumB-TL) combines two important emergent properties of an ecosystem (energy flow, in ter

216 ctions within oral biofilms give rise to the emergent properties of persistence, stability, and long-

217 This creates essential, network-level emergent properties of precise, high-amplitude oscillati

218 al organization in population codes could be emergent properties of randomly connected networks.

219 mediated behaviour can scale up to shape the emergent properties of social networks.

220 lecules for gene regulation by combining two emergent properties of the guanine (G) heterocycle in DN

221 with bacterial growth rate, are predicted as emergent properties of the model.

222 Our analysis examines three emergent properties of the networks-social specializatio

223 bustness of performance coevolve, both being emergent properties of the same elastic-recoil mechanism

224 y specific pacemaker hub that determines the emergent properties of the SCN timekeeper.

225 p interpret unexpected outcomes by revealing emergent properties of the system due to interactions am

226 ical cross-scale interactions that result in emergent properties of the system.

227 istributed rate-across-sites are shown to be emergent properties of this model while being consistent

228 They are emergent properties that can be tuned by varying the rel

229 ), enabling the design of metamaterials with emergent properties that escape a standard group theory

230 These condensates have common features and emergent properties that provide the cell with regulator

231 e been recently found to exhibit a number of emergent properties that the individual layers themselve

232 By using C-EISA, new emergent properties will be closely tied with the nature

233 her provides a synthetic design paradigm for emergent properties, including Rashba-Dresselhaus spin-p

234 r, often obscures key elements that regulate emergent properties.

235 f the developing human immune system and its emergent properties.

236 reate the ensembles of biomacromolecules for emergent properties/functions in a myriad of cellular pr

237 emaker activity in longitudinal muscle is an emergent property as a result of integrated processes in

238 nce of network modularity, variation in this emergent property is poorly understood in complex natura

239 Importantly, prestige was an emergent property of participants' behaviour during the

240 s in niche breadth represent a transient and emergent property of recent geographic range dynamics an

241 t vectorial capacity can be understood as an emergent property of simple behavioral algorithms intera

242 rical and mechanical behaviours of LM are an emergent property of SMCs and ICC-SS.

243 number of items successfully retrieved is an emergent property of stochastic sampling, requiring no e

244 Instead, it is an emergent property that depends on the population's intri

245 This is a scale emergent property that needs better consideration in cou

246 ates and absent in nonhuman apes and because emergent provisioning would have been subject to paterni

247 rinsically different platforms for exploring emergent quantum phenomena and designing new functionali

248 tructure of 2DPs and present a route to tune emergent quantum phenomena in 2DP hybrid van der Waals h

249 tion may offer a rich avenue for discovering emergent quantum phenomena in condensed matter.

250 Emergent quantum phenomena in electronically coupled two

251 Magnetic monopoles have been proposed as emergent quasiparticles in pyrochlore spin ice compounds

252 We further discussed emergent questions concerning cellular level responses t

253 Such emergent relationships highlight the potential of causal

254 Sensitivity analysis excluding emergent resections to define USBR did not alter the res

255 ncing did not identify baseline or treatment emergent resistance associated substitutions.

256 men at week 48, with no virologic failure or emergent resistance reported with DTG/3TC, supporting it

257 Treatment-emergent resistance to any study drug occurred in two (1

258 lures (2 DTG, no acquired resistance; 1 EFV, emergent resistance to nucleoside reverse transcriptase

259 rable treatment for people with HIV, with no emergent resistance.

260 ycling, our mechanistic understanding of the emergent responses of phytoplankton communities is poor.

261 enced stimuli could instructively sculpt the emergent responses, visually naive ferrets were exposed

262 interactions between two monomers but is an emergent result of multibody interactions.

263 P<0.0001), and across elective, urgent, and emergent revascularizations.

264 We conclude by summarizing novel and emergent RNR targeting motifs for cancer and antibiotic

265 No emergent safety issues were reported.

266 efficacy, initial overall survival, and late-emergent safety results.

267 CO(2) fertilization is the dominant cause of emergent SCA trends at northern sites south of 40 degree

268 Therefore, collective behaviour can be an emergent selective driver for undifferentiated multicell

269 iprocal chemotactic interactions to generate emergent self-organization and collective behaviours rem

270 tworks provide a putative path to predicting emergent shape from underlying genetic programs.

271 Contrasting emergent soil structures exert selective pressures upon

272 se subsets have the characteristics of newly emergent SSCs.

273 n cell mechanical properties when estimating emergent stress fields from collective cell behavior.

274 The emergent structural and functional properties of such pr

275 The emergent structure and heterogeneity of urban landscapes

276 ion of a locked superstructure equipped with emergent structure-function relationships.

277 No patients required emergent surgeries.

278 ect or predict strangulation, which requires emergent surgery.

279 cross the United States referred an apparent emergent surgical case to the ED, potentially delaying c

280 ls, therapy-induced senescence can establish emergent susceptibilities to otherwise ineffective chemo

281 tional groups within a framework, leading to emergent synergistic effects.

282 to the mapping of genetic interactions in an emergent system.

283 From established to emergent technologies, doping plays a crucial role in al

284 particle pairs (LPC-NPPs) to understand this emergent tetratic order and show that LPC-NPPs can be us

285 An emergent theme is that cancer-associated mutations tend

286 Emergent topological insulators (TIs) and their design a

287 Mimicking key emergent traits may allow upscaling of restoration in ma

288 advance restoration science by mimicking key emergent traits that locally suppress physical stress us

289 are transplanted within structures mimicking emergent traits that suppress waves or sediment mobility

290 The most common late-emergent treatment-related grade 3 or 4 adverse events r

291 The structure of the emergent trophic network and the rate at which primary r

292 , winds, heat and freshwater fluxes) and the emergent turbulence, which transfers energy to dissipati

293 It is an emergent, unitless property that is difficult to measure

294 ath, hospitalization for heart failure or an emergent/urgent heart failure visit requiring intravenou

295 NO in the blood relative to the tissue drove emergent vascular dynamics.

296 by limiting DOC-contributing factors, e.g., emergent vegetation, and supporting pH-increase processe

297 trice Kleinberg Neuwirth Fund and Fast Grant Emergent Ventures funding from the Mercatus Center at Ge

298 nes against a range of established and newly emergent viral pathogens.

299 e have produced a number of typing tools for emergent viruses that have caused large outbreaks, such

300 COVID-19 is an emergent, worldwide public health concern.