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1 bes for biomedical research and diagnostics, emphasizing the needs and opportunities that have been u
2 remodeling beyond a mere structural role and emphasize the need for a better understanding of this mo
3 fication associated with MGP dysfunction and emphasize the need for a comprehensive approach to this
9 In this review, we summarize recent work and emphasize the need for a solid theoretical framing to gu
16 in situ as a precursor to breast cancer and emphasize the need for appropriate treatment in hopes of
17 of this unique developmental window, we also emphasize the need for causal studies to clarify the par
19 nd-specific chlorine isotope analysis (CSIA) emphasize the need for chlorine isotope standards that b
24 ported requirement of MELK in cancer, and to emphasize the need for continued elucidation of the func
26 of G12P[8] strains in the United States and emphasize the need for continued monitoring of rotavirus
27 H1N1 viruses with avian influenza virus and emphasize the need for continued surveillance of influen
28 t can both directly or indirectly damage DNA emphasize the need for developing facile methods to asse
32 f sampling effort as an explanatory variable emphasize the need for effective monitoring and risk ass
37 raphic differences in these associations and emphasize the need for further investigation of eating d
39 cellular transport of LNPs carrying mRNA and emphasize the need for greater insights into surface com
41 however, current relapse and mortality rates emphasize the need for improved therapeutic strategies.
42 of CR6261 and CR9114 against H2 viruses and emphasize the need for in vivo evaluation of bNAbs.IMPOR
44 bility and multi-year periodicity in biomass emphasize the need for long-term data to detect trends a
51 scheme that has been previously proposed and emphasize the need for more research on the chemistry an
54 mple of the antibiotic-resistance crisis and emphasize the need for new approaches to treat and preve
55 ic study of the human inner ear continues to emphasize the need for non- or minimally invasive clinic
57 rities in the occurrence of DM, CKD, and HTN emphasize the need for prevention and treatment options
59 ulted specifically from exome sequencing and emphasize the need for rigorous statistical evaluation o
60 incidence in these North American cities and emphasize the need for scale-up of opioid agonist therap
62 in regions of dengue virus (DENV) endemicity emphasize the need for sensitive and specific serodiagno
66 n the geomechanical responses of these sites emphasize the need for systematic geomechanical appraisa
67 rtance for decision making, and, as such, we emphasize the need for the functioning of an endocarditi
68 valid in vitro models of malignant cells and emphasize the need for validation of primary tumor cultu
72 the global outbreak of an influenza pandemic emphasized the need for an effective vaccine adjuvant.
74 e and formidable immune evasion arsenal have emphasized the need for more effective antimicrobial app
75 zing radiation (IR) to large populations has emphasized the need for rapid and reliable methods of bi
77 s for the current gene therapy strategy that emphasizes the need for a combinatorial therapy to both
79 en across the different developmental stages emphasizes the need for a holistic life-cycle approach t
82 formation changes over vocal development and emphasizes the need for an embodied view of song motor l
83 formation changes over vocal development and emphasizes the need for an embodied view of song motor l
85 ted population of recurrent BV patients that emphasizes the need for and a pathway to a possible prog
88 ally limited to surgery and radiation, which emphasizes the need for better understanding of this dis
89 ive biology of mechanosensitive channels and emphasizes the need for care in analysing protein comple
91 y patients to checkpoint-inhibitor therapies emphasizes the need for combination immunotherapies to p
92 e current gene therapy strategy for LCA that emphasizes the need for combinatorial therapies to both
93 and Ag NPs and enhance their toxic potential emphasizes the need for conducting future toxicity studi
94 rising in Hg(II) bioassays with cysteine and emphasizes the need for considering changes in chemical
98 al mus-scale transitions in the loops, which emphasizes the need for extended simulations in studies
99 both natural and crop host-pathogen systems emphasizes the need for flexibility in thinking and a wi
100 demonstrated for the H3.2010.1 IAV in swine emphasizes the need for further characterization of viru
101 of IAV-associated cardiovascular damage and emphasizes the need for further clinical research in thi
102 y in preclinical studies can be obtained and emphasizes the need for high quality and rigorous method
103 for chronic musculoskeletal manifestations, emphasizes the need for identification of genetic determ
104 and nurse-patient interaction of nurses and emphasizes the need for implementing institutional polic
107 how the search for the origins of SARS-CoV-2 emphasizes the need for integrated phylogenetic methods.
114 he rapid acquisition of delamanid resistance emphasizes the need for optimal use of new drugs, the ne
116 or miR-216a, miR-216b or miR-217 in PDAC and emphasizes the need for phenotypic evaluation of miRNAs
117 ty limits for early-life human exposures and emphasizes the need for re-evaluation of the exposure ri
118 oacrylate generated by metabolic enzymes and emphasizes the need for RidA to quench this reactive met
119 ch as the zwitterionic Fos-choline-12, which emphasizes the need for simple validation assays like th
120 etween traditional prognostic markers and RS emphasizes the need for standardized assessment and supp
123 on of the 2009 pandemic H1N1 influenza virus emphasizes the need for universal influenza vaccines tha
127 ance the treatment of rectal cancer, further emphasizing the need for a multidisciplinary approach to
128 t and implementation barriers are discussed, emphasizing the need for a systems approach to designing
129 he true heritability is bounded away from 0, emphasizing the need for accurate confidence intervals.
130 ndations for future miRNA biomarker studies, emphasizing the need for accurate interpretation within
131 se knockouts for Shoc2 are embryonic lethal, emphasizing the need for additional animal models to stu
132 are vertically infected with HIV-1 annually, emphasizing the need for additional interventions to eli
133 likely larger than that for the State total, emphasizing the need for additional measurements in unde
134 ine inactivation of Cryptosporidium oocysts, emphasizing the need for additional pool remediation opt
135 combined with a low treatment satisfaction, emphasizing the need for adequate treatment, especially
137 inics, and neurovascular emergency services, emphasizing the need for appropriate blood-sensitive mag
138 mmentary highlights the article by Ng et al, emphasizing the need for autopsies to better model infec
139 s, which could confound certain experiments, emphasizing the need for careful attention to control st
140 d model compared with the LeuBAT structures, emphasizing the need for careful experimental verificati
141 - and tissue-specific cysteine-omes, further emphasizing the need for characterization of diverse mod
143 the target for many therapeutic strategies, emphasizing the need for comprehensive molecular maps of
144 ained by the variation of single parameters, emphasizing the need for comprehensive sensitivity analy
145 een computational and experimental chemists, emphasizing the need for computation to predict experime
146 at environmentally relevant concentrations, emphasizing the need for consideration of such interacti
147 PD-1 and IL-10 mediated immune inactivation, emphasizing the need for designing immunotherapies capab
148 cer regions being absent in another, further emphasizing the need for effective hardware and software
149 l, community, and agricultural settings; and emphasizing the need for establishing regional active su
150 fe style factor affecting human health, thus emphasizing the need for evidence-based dietary guidelin
151 ent enough when used as a single agent, thus emphasizing the need for faster acting agents with more
152 atterns were encountered in 31% of patients, emphasizing the need for further evaluation in larger se
153 gnificant spatial variability in subsidence, emphasizing the need for further measurement, which coul
154 patially and temporally resolved (13)C MRSI, emphasizing the need for further MR methodologic develop
155 directions for isoform function prediction, emphasizing the need for heterogeneous genomic data inte
157 y recipient tumor cells were not detectable, emphasizing the need for improved additive MiHA-specific
158 ng other countries in the region and beyond, emphasizing the need for improved EV-A71 surveillance an
159 fects on lung function and disease severity, emphasizing the need for improved pediatric asthma contr
160 ed prostate cancer (CaP) becomes metastatic, emphasizing the need for improved targeted therapies.
161 terconnected, forming a small-world network, emphasizing the need for international cooperation.
162 from these large collaborative initiatives, emphasizing the need for life-long follow-up of survivor
163 r from interobserver diagnostic variability, emphasizing the need for new diagnostic modalities.
164 omes have not improved over the past decade, emphasizing the need for new therapeutic interventions,
165 fectiveness for risk stratification, further emphasizing the need for optimal patient selection for c
166 ly from published sets and between patients, emphasizing the need for patient-specific adjustment.
167 r following hospital discharge for COVID-19, emphasizing the need for randomized data to inform recom
169 cation is highly variable in space and time, emphasizing the need for spatially and temporally resolv
170 are crucial for cell-to-cell communication, emphasizing the need for spatially resolved data on cyto
171 y responses required T cell help to develop, emphasizing the need for T-B collaboration for long-term
172 rvival in survivors who develop CVD is poor, emphasizing the need for targeted prevention strategies
173 measured in infancy persist into childhood, emphasizing the need for targeted therapeutic interventi
174 sability, ancestry bias and transferability, emphasizing the need for the next wave of studies to foc
175 tion with corresponding lung volume changes, emphasizing the need for tight control over lung volume
176 8 of 1231] vs 3.7% [121 of 3311]; P < .001), emphasizing the need for timely advanced treatment.
177 degree of negative or positive memory bias, emphasizing the need for valence-based accounts of the a
178 ially higher than the general US population; emphasizing the needs for studies of the subunit vaccine
181 of nephrocalcinosis and that our case series emphasizes the need of a well-organized retrospective st
182 ss preclinical tests fail in these patients, emphasizing the need of improved preclinical models to t
187 t passerines and their offspring, these data emphasize the need to appraise the potential ecotoxicolo
189 ase phenotypes within the patient population emphasize the need to better understand the mechanisms b
191 calculators to tropical farming systems and emphasize the need to broaden the scope of the underlyin
192 ease patients with early visual symptoms and emphasize the need to clarify the pathophysiological cha
195 assumes negative effects of nonnatives, and emphasize the need to consider context-dependence and in
197 ocally mirrors ongoing neuroinflammation and emphasize the need to consider non-inflammatory interpre
199 grees of visual impairment in these patients emphasize the need to continue refining our understandin
200 better inform donor candidates, and further emphasize the need to develop policies so that living ki
201 held responsible, current guidelines do not emphasize the need to differentiate atrial functional MR
204 n as a function of juvenile density and time emphasize the need to evaluate their roles through later
205 t into how a small molecule binds an IDP and emphasize the need to examine motions on the low microse
206 on in the development of the human tumor and emphasize the need to experimentally determine the signi
211 s and the lack of targeted therapies for TSS emphasize the need to identify key players of the storm'
212 n development for alcohol use disorder (AUD) emphasize the need to identify novel molecular targets a
217 pes can be maintained within populations and emphasize the need to investigate interactions between s
218 Vs circulate independently of each other and emphasize the need to investigate within-clade antigenic
221 cts on the exchange of greenhouse gases, and emphasize the need to project future hydrological regime
225 iomyelitis infection in Pakistan and further emphasize the need to scale-up clinical and environmenta
226 snow-ice interactions across the Arctic, and emphasize the need to scrutinize mechanisms governing cy
231 tone fluctuations between arousal states and emphasize the need to understand the effect of disruptio
234 tion, which is generally overlooked and thus emphasize the need to use cellularly derived and biologi
236 ported infections; this devastating epidemic emphasized the need to understand the mechanisms to coun
238 chwann cell function in the adult animal and emphasizes the need to approach potential therapeutic mo
245 direct and indirect economic effect of ASDs emphasizes the need to continue to search for effective
246 ver, the emergence of drug-resistant mutants emphasizes the need to develop additional agents that ha
247 lcium content usually found in wine and must emphasizes the need to develop alternative and appropria
248 ergic signaling is controlled in AT and also emphasizes the need to develop better methods to assess
249 hey will be captured by limited biopsies and emphasizes the need to develop therapies specifically ta
251 prognosis and lack of efficacious treatment emphasizes the need to elucidate the pathways playing a
253 to the multiple chemicals already detected, emphasizes the need to further investigate the migration
257 ing processes in functionally important ways-emphasizes the need to integrate multiple mechanisms of
261 other cyanopeptides along with microcystins emphasizes the need to make them available as reference
262 an outperform their natural counterparts and emphasizes the need to optimize donor-acceptor distance
264 artifacts in cancer genomics data, our study emphasizes the need to survey the diversity of normal as
265 in cancer cells that prevents apoptosis, and emphasizes the need to synergize nanoparticle design wit
268 es in the cortices of sporadic disease cases emphasizes the need to understand the link between alpha
269 n shaping geographic diversity patterns, and emphasizes the need to understand the mechanisms underpi
272 ALAN can broadly effect migratory behavior, emphasizing the need to better understand the implicatio
273 h significantly increased risk for bleeding, emphasizing the need to carefully determine if and when
274 e variability in long-term nitrogen loading, emphasizing the need to consider climate change risks wh
275 e relative richness of these three families, emphasizing the need to consider the incomplete nature o
276 ly associated with platinum drug resistance, emphasizing the need to directly measure the intratumor
278 roposed criteria build on a conceptual model emphasizing the need to distinguish climatic and human e
279 us characterization techniques is discussed, emphasizing the need to employ multiple techniques in co
280 atory and cytoskeletal remodelling pathways, emphasizing the need to explore biochemical alterations
281 for patients with CAPS and residual disease, emphasizing the need to explore other NLRP3-mediated pat
282 nt predators on prey metacommunity assembly, emphasizing the need to explore the role of predator die
283 xicities that are unique to immunotherapies, emphasizing the need to familiarize the oncology practit
284 e >70 affected individuals reported to date, emphasizing the need to identify the underlying genetic
285 to microbiota research are also highlighted, emphasizing the need to move beyond studies of correlati
286 largely ineffective in overcoming stunting, emphasizing the need to obtain better understanding of i
287 ate C.albicans-mediated mucosal inflammation emphasizing the need to optimize the applied antifungal
289 trum to that found in the adult counterpart, emphasizing the need to promote sun protection practices
290 e refinements to current policies, including emphasizing the need to reduce random encounters more th
291 stimulate T cell responses in vivo, further emphasizing the need to regulate both pathways to induce
292 inst a backdrop of nutrient over-enrichment, emphasizing the need to separate these effects to gauge
293 traditional stoves with clean technologies, emphasizing the need to shift in the long term to near e
294 and quality of life (QOL) they have enabled, emphasizing the need to sustain our national investment
295 f diversity and eutrophication on stability, emphasizing the need to understand how drivers of global
296 altered our understanding of tumorigenesis, emphasizing the need to understand how single stem cells
297 set by natural disasters are also presented, emphasizing the need to understand the magnitude frequen
298 nation of malignant cells during metastasis, emphasizing the need to understand the mechanisms contro
299 ngly associated with mortality than obesity, emphasizing the need to understand the nature of the rel
300 resistance have proven to be heterogeneous, emphasizing the need to use broad therapeutic approaches