ライフサイエンスコーパス: end

1 he motors' residence time at the microtubule end.

2 of the barrel can be evaluated at the distal end.

3 (>=stage 3) from year 1 onwards until study end.

4 continuous solid phases, is created for this end.

5 d biphenyl moieties attached to the vinylene ends.

6 ration of single spacers over two transposon ends.

7 rbed ends and SPIN90-Arp2/3 at their pointed ends.

8 n high-force production at both homotetramer ends.

9 amily proteins, are slow in populating these ends.

10 olated exopolysaccharides contained reducing ends.

11 at the 2'-hydroxyl group on the ribose at 3'-end (2'-O-methylation, 2'Ome) is critical for miRNA func

12 To this end, 37 spider phobic patients (PP) and 32 healthy contr

13 l millions of enemy civilians in the hope of ending a ground war that threatens thousands of American

14 To this end, a high-throughput, cellular NanoBRET assay was deve

15 To this end, a thiourea-cyclopropenium organocatalyst was employ

16 on-trivial signatures from discordant paired-end alignments, split-reads and read depth information t

17 In the end, all the 475 behaviors of supervisors to regulate au

18 e is the Kochetkov amination, where reducing end amines exist solely as the beta-anomer.

19 part refers to the part between the reducing end and the outmost branches.

20 ngating filaments with mDia1 at their barbed ends and SPIN90-Arp2/3 at their pointed ends.

21 does so by controlling the processing of DNA ends and the dynamics of DSBs.

22 res that capture RAG engaged with transposon ends and U-shaped target DNA prior to integration (the t

23 with basal-like BC, and efforts toward this end are currently underway.

24 All new Ascaris somatic chromosome ends are recapped by de novo telomere healing.

25 inter-chromosomal interactions at centromere ends are significantly weaker than those at telomere end

26 o generate libraries of compounds, with some ending as promising drug candidates.

27 )myofibres instead of localising at myofibre ends as in wild-type.

28 Loss of barbed-end binding increases nucleation by Spire and synergy wi

29 lowed by recruitment of the microtubule plus end-binding protein EB1/EBP-2 around the wound and actin

30 facilitates homologous recombination at two-ended breaks and contributes to repair within heterochro

31 The reaction affords aldehyde end-capped polymers whose molecular weight can be tuned

32 pairs helps to explain the success of sticky-ended CMP association and changes the conception of new

33 n of the Callascope camera to a $20,000 high-end colposcope demonstrated that the Callascope camera m

34 were followed up over a 1-year period (study end date, March 31, 2019).

35 Here we present an End-to-End deep learning framework, circDeep, to classify circu

36 extract, a new study finds that microtubule end density negatively influences their assembly rates.

37 As a result, LV end-diastolic wall thickness-to-chamber radius (h/R) rat

38 n is the primary motor for microtubule minus-end-directed transport and is indispensable to eukaryoti

39 To this end, egg yolk was taken as a model matrix.

40 h less tracheal collapse and air trapping at end-expiration chest CT.

41 invasive ventilation can use lower positive end-expiratory pressure (PEEP) in critically ill patient

42 to avoid volutrauma, together with positive end-expiratory pressure to increase the fraction of open

43 imply an "atypical" response to the positive end-expiratory pressure.

44 hat, in theory, could use their resources to end extreme poverty.

45 proceed from the reducing to the nonreducing end for a better yield.

46 Telomeres protect chromosome ends from inappropriately activating the DNA damage and

47 hardware and software interfaces for end-to-end functionality.

48 ion trap mass spectrometer that uses a front-end glow discharge source to generate radical fluoranthe

49 interface, implying the presence of reducing-end glycans at this location where the capsule is attach

50 echniques should be a consideration when the end goal is to utilize the model in a clinical setting.

51 by nuclear magnetic resonance spectroscopy, end group analysis, and chain extension experiments.

52 To this end, here we sought to reduce the complexity of cellular

53 Osler ended his address on a more somber note, seemingly surpr

54 To this end, HIV-1 patients on antiretroviral therapy who are re

55 radation by ClpC1, which requires disordered ends in its protein substrates.

56 At study end, in intervention communities, 1228 people living wit

57 At end-induction, 98.8% of evaluable participants had at le

58 The diaphragm thickness at end-inspirium and thickening ratio values correlated inv

59 gle Nucleotide Polymorphism) variant and the end is disease outcome.

60 The mere requirement to this end is through the increase of temperature.

61 ation of the nickel complex at polymer chain ends is evidenced by nuclear magnetic resonance spectros

62 To this end, it is important to exploit multiple data streams th

63 plays a critical role in the non-homologous end joining (NHEJ) repair pathway and the DNA damage res

64 homologous recombination over non-homologous end joining and potentially other mutagenic pathways of

65 minal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) assay and immunohistochemistry for

66 rase mediated deoxyuridine triphosphate nick end labeling assay.

67 f Nkx3.1 reduces proliferation, enhances DNA end-labeling, and protects from DNA damage, ultimately b

68 To that end, less is known about how the virus may impact differ

69 ction is regulated by the movement of end-to-end-linked troponin-tropomyosin complexes over the thin

70 To this end, mice deficient in type I, II, or III IFN receptors

71 To this end, mouse skin infection models allow researchers to ex

72 We propose an end-to-end neural nested event extraction model named DeepEvent

73 fference was found between the beginning and end of 12.5 h day shifts (88.6% vs 73.6%).

74 orming base-pairing interactions with the 3' end of 16S rRNA, mRNA Shine-Dalgarno (SD) sequences posi

75 nitial randomized study were deceased at the end of 2017.

76 cus is on results described from 2007 to the end of 2019, yet relevant pioneering transformations are

77 elevant difference between the beginning and end of 8 h day shifts (92.2% vs 97.3%).

78 e two neural states tended to fall at either end of a neural hierarchy that is thought to reflect the

79 The latency from the end of an effective stimulus to the start of head moveme

80 ecide when to initiate a given action at the end of an interval.

81 ere the most abundant in packed boxes at the end of cold storage.

82 At the end of dasatinib induction therapy (day 85), 29% of the

83 Patients were examined at the end of each 4-month period (at 5 and 9 months after impl

84 nced by employing a 3'-amino group at the 3'-end of each oligonucleotide, in combination with an N-al

85 Saliva and blood samples were taken at the end of each treatment to analyse the abundance and diver

86 nets whose maturation is associated with the end of early critical periods of synaptogenesis.

87 tisepsis was found between the beginning and end of extended shifts: In physicians, adequate hand ant

88 End of follow-up was June 30, 2018.

89 ing from after the blood draw through to the end of follow-up, contrasting vaccine recipients with di

90 nths was 65 and 54% remained on TG until the end of follow-up.

91 MRD at the end of induction therapy was high (>=10(-2) cells) in 61

92 d 561 (71%) participants at diagnosis and at end of induction, respectively.

93 uced progeny at 72 particles per cell at the end of its lytic cycle.

94 From the end of May to the end of July , the estimated reproduction number has a me

95 End of life care is often inadequate for people with dem

96 n-European countries between January and the end of May 2020.

97 From the end of May to the end of July , the estimated reproducti

98 many intracellular cargoes towards the minus end of microtubules (MTs).

99 ep deprivation (3 h sleep opportunity at the end of night), crossed-over with a full sleep condition

100 d at least two viral loads in the year after end of pregnancy).

101 ta-1,6 glucosidic linkages from non-reducing end of short chain oligosaccharides, alkyl and aryl beta

102 change in Zn speciation was observed at the end of the 12-week experiment, and phosphate was found t

103 At the end of the 18-week study, stifle (knee) joints from all

104 Nineteen dogs at the end of the 19-week chemotherapy protocol (8 Complete Res

105 vironmental conditions, as predicted for the end of the 21st century, could thus disrupt the communit

106 gate or allosteric pathway mutations at one end of the barrel can be evaluated at the distal end.

107 atic interaction between the charges on each end of the bridge and can be modified by altering these

108 ericentriolar material (PCM) to the proximal end of the centriole.

109 nd boreal forests by ~0.2 Gt per year at the end of the century.

110 romaeosaurids were still diversifying at the end of the Cretaceous.

111 consequence of low food availability at the end of the Cretaceous.

112 production, and biological diversity by the end of the Ediacaran Period.

113 d that a single follow-up examination at the end of the first year after treatment completion combine

114 sed in schizonts, be localized at the apical end of the merozoite, and preferentially bind reticulocy

115 valently linked viral polymerase from the 5' end of the minus strand [(-)strand] of viral relaxed cir

116 The beginning of the end of the nanomedicine hype.

117 to the S. pombe NPF Dip1 and attached to the end of the nucleated actin filament.

118 fter an infection and worse CT scores at the end of the observation period.

119 d animals disappeared from the region at the end of the Pleistocene.

120 rease in pheromone reception at the proximal end of the sensors.

121 xazole was most frequently prescribed by the end of the study period.

122 At the end of the study, mice were euthanized and pelted to ass

123 ne/saline administration continued until the end of the study.

124 Features at each end of the substrate overcome this barrier and promote r

125 ased significantly from the beginning to the end of the trial.

126 isphere tropospheric circulation towards the end of the twentieth century, including a poleward shift

127 ation of patients from their families at the end of their lives.

128 The minimal duration of follow-up after end of therapy was two months.

129 ximum (LGM), the present (2006-2015) and the end of this century (2100) by mapping our model of Trich

130 le autonomy results in expertise gaps at the end of training.

131 rence change from baseline to week 3 through end of treatment [EOT] in MADRS-6 and -10 versus placebo

132 assessed by impaired RAD51 foci formation on end of treatment biopsy.

133 At 6 months after the end of treatment in the intention-to-treat analysis, 11

134 eek 2, interleukin 18 levels declined by the end of treatment, sCD14 levels did not change, and sCD16

135 k, egg, peanut, sesame, or tree nuts, at the end of up-dosing, and after 6 months of follow-up.

136 at the gate conformation of the two opposite ends of 20S are coupled: binding one ATPase opens a gate

137 ing the temperature gradient between the two ends of a thermoelectric material, in order to ensure co

138 hat preferentially interact with the charged ends of an I-BAR domain, we find clustering of phosphati

139 ulation of H3K14ac levels in their 5' and 3' ends of its target genes.

140 ed intracellular transport towards the minus-ends of microtubules.

141 Polymerases and exonucleases act on 3' ends of nascent RNAs to promote their maturation or degr

142 to midcell, oscillating between the opposite ends of the cell and preventing FtsZ-ring misassembly at

143 d Cas9 target sequences (tCTSs) added at the ends of the homology-directed repair (HDR) template inte

144 optic nerve head (ONH) and optic chiasm (OC) ends of the optic nerve were recorded along with the ent

145 extracellular matrix that ligate the severed ends of the spinal cord.

146 Provider COC had a greater effect on end-of-life care expenditures than site COC did, which i

147 with hospice services are likely to optimise end-of-life care for patients with haematological malign

148 In many cases, the metal concentration in end-of-life products is lower than that in natural ores.

149 as defined as complete response (CR) rate on end-of-treatment (EOT) imaging or with pathologic confir

150 The study documents the end-of-treatment outcomes, culture-conversion rates, and

151 Importantly, our barriers end on the same energy on which they start.

152 011 through March 2014; randomized treatment ended on December 31, 2017, and this was the final date

153 omposition as 2-Tb but with both side-on and end-on bonding of the N(2) unit in the same crystal, [K(

154 otubules, mediating microtubule zippering or end-on microtubule interactions, depending on their cont

155 To this end, one of the primary tools in fluorescence microscopy

156 ain clinically meaningful conclusions at the end or during a trial, for many treatment strategies, si

157 Progressive end-organ damage, partly related to a systemic vasculopa

158 elial dysfunction, and increases the risk of end-organ damage.

159 End-organ effects are diverse, resulting in both cogniti

160 spitalized patients who had Covid-19 without end-organ failure in a 1:1 ratio to receive either LY-Co

161 End-organ impairment has received relatively little rese

162 Thus, loss of USH2A in corpuscular end-organs reduced mechanoreceptor sensitivity as well a

163 ver, do not readily enter, maintaining minus-end-out polarity.

164 racing of transmission chains is critical to end outbreaks and to inform prevention measures.

165 rates (kloop and kunloop) of DNA with sticky ends over three helical periods (100-130 bp) using singl

166 The end-Permian mass extinction was the most severe mass ext

167 nd heparin monotherapy regarding the primary end point (180-day all-cause death, myocardial reinfarct

168 MRI-derived myocardial strain for a combined end point (events) of heart failure hospitalizations and

169 t (2.3% versus 1.4% for the primary efficacy end point at 3 years, Gail-Simon qualitative P(interacti

170 The primary end point for this analysis was the composite of (1) dea

171 0]; P=0.000001); the key secondary composite end point occurred in 16.6% versus 12.1% (HR, 0.69 [95%

172 The primary composite end point occurred in 24.7% of placebo-treated patients

173 nificantly reduce the primary cardiovascular end point of major CVD events (composite of myocardial i

174 eted the trial with ascertainment of primary end point status.

175 The primary end point was 3-year BPFS.

176 The primary end point was concordant S aureus colonization by 90 day

177 The primary end point was endogenous insulin production, as assessed

178 The clinical end point was ischemic stroke.

179 The primary end point was met, with an sCR rate of 60% after 8 cycle

180 The primary end point was met, with the ORR reaching 60.9% (95% CI,

181 Primary end point was overall survival (OS) evaluated using adju

182 The primary end point was percentage improvement in Eczema Area and

183 The primary end point was the percentage of patients with an objecti

184 e clinical composite score (primary efficacy end point), quality of life, LV structural remodeling (

185 low-up, 160 patients experienced the primary end point, and 88 experienced the arrhythmic end point.

186 g), the individual components of the primary end point, definite stent thrombosis, or stroke.

187 Regarding the primary end point, no intergroup differences were observed for t

188 The primary efficacy end point, percentage change in total plaque volume at 9

189 end point, and 88 experienced the arrhythmic end point.

190 re observed in the components of the primary end point.

191 ) were independent predictors of the primary end point.

192 A primary end-point event occurred in 187 patients (6.8%) in the c

193 Two primary safety end-point events occurred in the ablation group (Kaplan-

194 ion individually or in combination for the 6 end points at 3 years.

195 Secondary end points included angiographic and safety outcomes.

196 Secondary end points included overall survival and safety.

197 Microbiome end points included SER-287 engraftment (dose species de

198 We compared the adjudication of prespecified end points made by investigators and by the CEC.

199 tion and after 2 weeks, as primary surrogate end points of efficacy and safety, respectively.

200 t Association class on presentation, and the end points of mortality and heart failure admissions in

201 Secondary end points were 5-year locoregional control and disease-

202 Primary and secondary end points were assessed in a hierarchic model to compar

203 The primary safety end points were device related death or adverse events,

204 Secondary end points were locoregional control, local control with

205 ion and exclusion criteria, selected primary end points, and comparator populations to emulate those

206 benefit with respect to all other secondary end points, including the time to first symptomatic skel

207 Of the 6 prespecified secondary end points, none showed a statistically significant diff

208 and level III studies have variable primary end points, study design limitations, and only short-ter

209 have been shown to improve various oncologic end points.

210 .97]) but not stroke or other cardiovascular end points.

211 tochore-fibers by persistently favoring plus-end polymerization, not by increasing polymerization rat

212 Towards this end, positron emission tomography (PET) imaging has emer

213 ersions because CO(2) is an intermediate and end-product of the digestion process and modifies the ca

214 nuria, and suppression of advanced glycation end-product signalling.

215 tion of total fluorescent advanced glycation end products (AGEs) and Amadori adducts were determined.

216 rization is crucial to define the quality of end products and to describe the evolution of processes

217 AGE (soluble receptor for advanced glycation end products) strongly associate with ARDS risk.

218 Advanced glycation end-products (AGEs) accumulate during prolonged hypergly

219 s on a seven-point Likert scale or with open-ended questions.

220 g, which closely mimics the behavior of dual-ended readout, with the additional benefit of improved c

221 be size-selected to enable merging of paired end reads and should be sequenced in the PE150 format wi

222 Importantly, the paired-end reads that are properly aligned to the bovine Y sequ

223 assembled from short Illumina 150 bp paired-end reads.

224 ccrued from 5 Surveillance, Epidemiology and End Results Program sites and a US prostate cancer regis

225 This process appears to follow the N-end rule and is mediated by ClpA/P protease and the ClpS

226 Accordingly, deletion or depletion of the N-end rule pathway ubiquitin E3 ligases in NatB mutants di

227 To this end, several new platforms based on single-molecule prot

228 Nine patients (42%) had end stage renal disease at a mean age of 10.6 years (6.5

229 gnitive Impairment and Imaging Correlates in End Stage Renal Disease, NCT01883349.

230 End-stage kidney disease patients presented frequently s

231 dependent risk factor for the progression to end-stage kidney failure, cardiovascular morbidity, and

232 Among HIV-infected, model of end-stage liver disease (aHR, 1.04; P < 0.001), body mas

233 End-stage liver disease (ESLD) is a major burden on publ

234 Patients with end-stage liver disease (ESLD) suffer from a high sympto

235 al Condition Category 83), 2.55 (2.35-2.77); end-stage liver disease (Hierarchical Condition Category

236 a parsimonious model consisting of Model for End-Stage Liver Disease (MELD) and LA at admission may p

237 too sick." Our primary outcome was Model for End-Stage Liver Disease (MELD) score at waitlist removal

238 Model for End-Stage Liver Disease (MELD) score-based liver transpl

239 alysis of covariance, adjusted for model for end-stage liver disease at time of hospital admission, s

240 olangiopathy that progresses to fibrosis and end-stage liver disease by 2 years of age.

241 patients undergoing peritoneal dialysis for end-stage renal disease but without cirrhosis were inclu

242 Patient survival with end-stage renal disease is longer after kidney transplan

243 monoclonal antibody tesidolumab (LFG316) in end-stage renal disease patients awaiting kidney transpl

244 estimated glomerular filtration rate (eGFR), end-stage renal disease, or death from renal causes), th

245 rs reduced heart failure hospitalization and end-stage renal disease.

246 ication of diabetes and the leading cause of end-stage renal failure.

247 c attack may dominate the process during the end stages of mortality in these conifers.

248 Michelassi II, or the end-to-side-to-side-to-end strictureplasty, is a variant of the original SSIS t

249 significantly weaker than those at telomere ends, suggesting that they are located in different regi

250 on between sex and LV reverse remodeling (LV end-systolic volume change) and sex and the composite ou

251 e a sustained carbon sink well before winter ended, taking up roughly 90 g/m(2) more carbon during th

252 ial to establishing NMJ reinnervation at the end target muscle.

253 ge number and Vegf-A expression increased in end target muscles after nerve injury and repair.

254 targeted by the World Health Organization's End TB Strategy ("effective global TB control").

255 High-end technical approaches help to untangle the substructu

256 resolution and pulmonary vaso-occlusions in End.TGFbetaRII-KO mice.

257 ase backtracking, and generate frayed primer-ends that are shuttled to the exonuclease site and excis

258 Any plus ends that reach a dendrite, however, do not readily ente

259 oronavirus 2 (SARS-CoV-2) may be required to end the coronavirus disease 2019 (COVID-19) pandemic(1-8

260 PPORT Act; (2) opportunities offered by the "End the HIV Epidemic" initiative; and (3) policy changes

261 feasible and represents a viable strategy to end the pandemic.

262 ccounting for baseline differences, at study end the proportion of people living with HIV who were di

263 be required to reach national targets of the ending the HIV epidemic initiative by 2030.

264 ing role in addressing the opioid crisis and Ending the HIV Epidemic.

265 To this end, this work investigates how motor cortical neural ac

266 artery blood flow, independent of changes in end-tidal PCO2 and blood pressure External carotid arter

267 d passive heat stress during isocapnia (i.e. end-tidal PCO2 was held constant) Submaximal cycling exe

268 we developed an imaging pipeline using plus-end tip tracking and intravital microscopy to quantify M

269 urization approaches its limits, bringing an end to Moore's law, performance gains will need to come

270 iding critical tools necessary to achieve an end to the global STIs epidemic.

271 d other enzymes that modify incompatible DNA ends to allow their ligation.

272 les to reach freshly polymerized microtubule ends, to which KIF5B binds poorly, likely because its co

273 Here we present an End-to-End deep learning framework, circDeep, to classif

274 cessary hardware and software interfaces for end-to-end functionality.

275 We propose an end-to-end neural nested event extraction model named De

276 contraction is regulated by the movement of end-to-end-linked troponin-tropomyosin complexes over th

277 The Michelassi II, or the end-to-side-to-side-to-end strictureplasty, is a variant

278 number of specialized microtubule (MT) plus-end tracking proteins (commonly known as +TIPs) to induc

279 ial and marine sediments associated with the end-Triassic mass extinction (ETE) c.

280 with non-type 2 inflammatory disease on one end, type 2 inflammatory, eosinophil-heavy disease on th

281 At the pointed end, unique contacts between the penultimate and termina

282 ting sanderlings defy long distances but may end up in winter areas with poor fitness prospects.

283 ssing conditions that better suit particular end-use applications and more environmentally friendly p

284 es over the traditional methods, such as the end-user customization and rapid prototyping, useful in

285 thods to attribute electricity production to end users.

286 e, suggesting cell programmes reach the same end using different mechanisms.

287 d during pool walking: the mean starting and ending values of plasma renin activity and serum aldoste

288 To this end, we analyzed a total of 1,027 spikes and 86 seizures

289 To this end, we coupled Raman spectroscopy and paper spray ioniz

290 To this end, we did a prospective observational study of 20 cons

291 To this end, we discuss a set of features that might be desirabl

292 To this end, we estimate the basic reproduction number [Formula:

293 To this end, we propose using MMP-targeting antibodies that can

294 In the end, we provided scenarios as guidelines for users to us

295 To this end, we report a self-replicating Epstein-Barr virus-bas

296 To this end, we used data from 415 maize hybrids evaluated in 4

297 To this end, we used the well-characterized iSLK.219 cell model

298 We end with a special emphasis on social behavior, discuss

299 e the formation of membrane protrusions, and ends with the formation of a highly constricted Did2-Ist

300 reaks were deemed controlled if transmission ended within 12 weeks or before 5000 cases in total.