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1 ported (up to 98:2 enantiomer ratio and >98% endo).
2 cs of apurinic/apyrimidinic endonuclease (AP endo).
3 dolin-1-one (E-5-exo), and isoquinolinone (6-endo).
4 ion with bacteria-derived endoglycosidase S (EndoS).
5 served sequence in the effector Endosulfine (Endos).
6 exon 4 of Sirt1 in endothelial cells (Sirt1(endo-/-)).
7 as I(Kr) density was similar between Epi and Endo (0.31+/-0.05 versus 0.36+/-0.07 pA/pF) at 20 mV.
10 decreased with administration of esmolol (v(endo) 1.4+/-0.2 cm/s [P<0.05]; SR 6+/-1 s(-1) [P<0.01]).
11 590+/-140 ms) and nonsustained focal waves (Endo: 1.2% versus Epi: 1.6%, P=0.669) were also observed
12 , I(Ks) densities were larger in Epi than in Endo (1.1+/-0.1 versus 0.43+/-0.07 pA/pF), whereas I(Kr)
13 (1-->4)-beta-D-xylanase, beta-D-mannosidase, endo-(1-->4)-beta-D-mannanase, alpha-D-xylosidase, beta-
14 all hydrolases screened: beta-D-xylosidase, endo-(1-->4)-beta-D-xylanase, beta-D-mannosidase, endo-(
16 (APD25) are reduced in hypertrophy (control: endo, 11.4+/-0.9 ms; mid, 8.2+/-0.9 ms; epi, 5.1+/-0.4 m
17 .2+/-0.9 ms; epi, 5.1+/-0.4 ms; hypertrophy: endo, 11.6+/-0.9 ms; mid, 10.4+/-0.8 ms; epi, 7.8+/-0.6
18 ) was lower in EPI (7 +/- 2 mM, n = 31) than ENDO (12 +/- 3 mM, n = 29), with MID being intermediate
19 rolonged in subepicardial myocytes (control: endo, 126+/-7 ms; epi, 96+/-10 ms; hypertrophy: endo, 91
22 endo-2-exo-3-dihydroxynorbornane bearing a 5-endo-[2,2-bis(trifluoromethyl)hydroxyethyl] substituent
25 e of fluorinated sugar rings for either a 2'-endo, 3'-exo (South), or a 3'-endo,2'-exo (North) confor
26 Epi: 46.8%, P=0.0194) and single wavefronts (Endo: 31.3% versus Epi: 28.1%, P=0.129) were the dominan
28 roducts formed upon addition of bromine to 3-endo-, 4-, and 5-methyl- and 3-endo-phenyl-substituted N
29 ation from intermediate rac-5 leading to the endo-[4 + 2] (endo-2) and exo-[2 + 2] (anti-3) cycloaddu
32 s in ligand protonation and the formation of endo (4a) and exo (4b) isomers of trans-[HFe(PNHP)(dmpm)
35 are symptoms associated with endometriosis (ENDO), a common condition among women that is characteri
36 here that Rad23 can bind Ho-endonuclease (Ho-endo), a nuclear protein that initiates mating-type swit
38 re generated by site-directed mutagenesis of EndoS (an endoglycosidase from Streptococcus pyogenes )
40 ndo), UA VSM, omental artery endothelium (OA endo), and OA VSM proteins were isolated and ERalpha and
41 3(S)Hyp residues, which are all down (Cgamma-endo), and the varphi/psi dihedral angles of the Xaa 3(S
42 tiarrhythmic drug therapy after endocardial (ENDO) and adjuvant epicardial (EPI) substrate modificati
43 report the results of combined endocardial (Endo) and Epi VT ablation and conducting channel (CC) el
45 [K(+)](o) from 5.4 to 15 mM caused both I(P)(ENDO) and I(P)(EPI) to increase, but the ratio remained
46 dividual sugars in equilibrium between S (2'-endo) and N (3'-endo) conformations, with S being prefer
47 ter endotoxin challenge, decreases in both v(endo) and SR were detected before decreases in shortenin
48 d trip cyclization is a sequence of 5-exo, 6-endo, and 5-exo cyclizations in which the last radical c
49 enynes are suitable substrates, and 5-exo, 5-endo, and 6-exo cyclizations lead to outstanding enantio
52 ully internally coordinated with all phenyls endo, and lithium is close to one terminal allyl carbon.
53 ancy under natural conditions, namely para-, endo-, and ecodormancy in summer, fall, and winter, resp
57 ford, without any significant selectivity, 6-endo- and 5-endo-substituted bicyclic lactone cycloadduc
58 semble in designer cellulosomes alongside an endo- and an exo-cellulase also converted to the cellulo
59 PBPs), rather than with low-molecular-weight endo- and carboxypeptidases, indicating that MreC might
60 and proteins demonstrates conservation among endo- and ectoparasitoids within the Apocrita (e.g., thi
62 ned by asynchronous activation of the atrial endo- and epicardial layer and transmurally propagating
66 W indicate that muscular connections between endo- and epicardium underlie EBW and that a slight degr
68 lidine incorporated lobelane analogues, endo,endo- and exo,exo-2,6-cis-diphenethyl-1-azabicyclo-[2.2.
71 earch has been applied to design a series of endo- and exo-3-(pyridin-3-yl)bicyclo[2.2.1]heptan-2-ami
72 substituted bicyclo[1.1.0]but-2-ylmethanols (endo- and exo-9) from 1,3-butadiene has been developed.
73 , ActE secretes a suite of enzymes including endo- and exo-cellulases, CBM33 polysaccharide-monooxyge
74 ell-suited to generate diversity at both the endo- and exo-cyclic fragments formed during the ring-cl
78 y using micrococcal nuclease, which has both endo- and exo-nuclease activity, to fragment the chromat
81 oxide-opening cascade that incorporates both endo- and exo-selective epoxide openings, each directed
83 ne with 2-cyclohexenone to give a mixture of endo- and exo-trans-6-amino-5-phenylbicyclo[2.2.2]octan-
84 thermocellum is a multiprotein complex with endo- and exocellulase, xylanase, beta-glucanase, and ac
85 rally known that a team of enzymes including endo- and exocellulases as well as cellobiases are requi
87 14 patients with severe developmental delay, endo- and exocrine dysfunction, impairment of the sensor
88 ain relief, quality of life [QoL]), medical (endo- and exocrine function), and clinical (reoperation)
90 zoidal-shaped Ag(5) moiety via Ag-N bonds to endo- and exocyclic nitrogens of cytosine and adenine.
92 king along microtubules and through the cell endo- and exocytic pathways can be next visualized via l
100 ms in which transport, receptor interaction, endo- and exocytosis, and degradation occur together.
101 1 functions as a dual Ca(2+) sensor for both endo- and exocytosis, potentially coupling these two com
107 y protein kinases occurs mainly by regulated endo- and exocytosis; (ii) it is independent of consensu
110 ure and exposing the tissue cells to various endo- and exogenous factors, including bacterial toxins.
115 SBR), detection, and signaling; yet, how its endo- and exonuclease activities regulate DSBR by nonhom
116 Artemis is a vertebrate nuclease with both endo- and exonuclease activities that acts on a wide ran
117 e been identified for the protein, including endo- and exonuclease activities, interaction with the H
118 l data show that this CR3 motif affects both endo- and exonuclease activity in vivo and both the nucl
120 ecB1-929CD enzyme has lost the single-strand endo- and exonuclease and the double-strand exonuclease
122 exhibits greatly increased susceptibility to endo- and exonucleases but retains a full complement of
127 tion of pyrophosphorolysis as well as in the endo- and exonucleolytic cleavage of the nascent RNA.
128 o the molecular principles governing diverse endo- and exonucleolytic cleavage specificities of membe
130 Ribosomal processing requires a series of endo- and exonucleolytic steps for the production of mat
131 rnal cleavages in plasma proteins created by endo- and exopeptidases, providing information about the
133 l cells, is catalyzed by specific subsets of endo- and exoribonucleases that together recycle RNA fra
136 pacers (ITS1 and ITS2), which are removed by endo- and exoribonucleolytic steps to produce mature rRN
138 ns of OEG ensheathment and variations of the endo- and perineurium formed by olfactory nerve fibrobla
139 N. gonorrhoeae to infect and invade both the endo- and the ectocervix of the normal uterine cervix.
141 These results were compared with lavage and endo- and transbronchial biopsy studies in normal contro
142 lipids, and carbohydrates and by detoxifying endo- and xenobiotic components, the liver plays an impo
143 rplay between RORalpha and LXR in regulating endo- and xenobiotic genes, which may have broad implica
144 computer program termed Discovery of General Endo- and Xenobiotics (DoGEX) was developed, which uses
145 0 enzyme engaged in the biotransformation of endo- and xenobiotics, including >50% of clinically rele
146 on of a wide variety of structurally diverse endo- and xenobiotics, including many therapeutic agents
151 presentatives of that family possessing only endo- and, in few cases, endo/exo-cellulase activities,
152 the replacement by RRP1 is coupled with the endo- and/or exo-ribonucleolytic cleavage of pre-rRNA re
153 I-TevI cleavage site (CS) and IS implicates endo- and/or exonuclease activities to resect the DNA se
159 tes were isolated from basal subendocardial (endo), basal midmyocardial (mid), and apical subepicardi
161 e in NCX current density (P<0.05) limited to ENDO (by 202%) and MID (by 76%) but not EPI myocytes (P=
164 R for lymphatic capillary endothelium (R(endo)), calculated from lymph/subsynovial concentration
165 current (Ito) in EPI but not in endocardial (ENDO) cardiomyocytes of UNx rats led to a decreased tran
166 d APD90 of M but abbreviated that of EPI and ENDO, causing a persistent increase in TDR; Torsade de P
168 P) from epicardial (EPI), M and endocardial (ENDO) cells and a transmural electrocardiogram were simu
174 between non-helical (C2-endo) to helical (C3-endo) conformations during formation of two distinct exc
177 are considerable lower in energy than their "endo" counterparts, with the "exo-entended" conformation
181 rs are also identified for the S -type (C2'- endo) deoxyadenosine conformations that occur in R32 and
182 evealed that the mode of cyclization (exo vs endo) depends on the protecting group on nitrogen, the o
184 sum of their isolated components (E(inc) = E(endo) - E(cage) - E(x)) and to their exohedral isomer en
186 an 88-kDa secreted protein, endoglycosidase (Endo) E, which is most likely responsible for this activ
187 plex, but shows that the sugar pucker is O4'-endo (East conformation), intermediate between the South
188 g angiostatin (PCI-Angio) or endostatin (PCI-Endo) effectively reduced angiogenesis using an in vivo
189 Three protonated isomers are formed (endo/endo, endo/exo, or exo/exo), which differ in the positio
192 e dielectric constant of the solvent and the endo/ exo ratio is found, but more polar solvents lead t
196 ving methyl iodide proceed from the concave (endo) face of the bicyclo[4.3.0]nonene ring system.
200 Equilibrium constants (Keq = [C2'-endo]/[C3'-endo]) for C2'-endo-C3'-endo interconversion at 25 degre
201 creased with administration of dobutamine (v(endo) from 2.2+/-0.3 to 3.8+/-0.2 cm/s [P<0.01]; SR from
203 ealed the partial 3'-OH polarization and H3'-endo-->exo ribosyl configuration at the spMTAN transitio
204 voltage was essentially identical in EPI and ENDO (half-maximal activation at 9-10 mM [Na(+)](i) or a
205 al and eucaryotic sequences similar to these endo- (HII and III) and exoribonucleases (II, PH and D).
206 erally decreased with increasing doses of rh-Endo; however, the effects were complex and in some anal
207 rived alkenyl sulfides were submitted to a 6-endo [I(+)]-induced cyclization, and the resulting 2-deo
208 erichia coli DNA glycosylases, endonuclease (endo) III and endo VIII, which recognize oxidized pyrimi
210 e evaluated recombinant human endostatin (rh-Endo) in a phase I trial designed to assess safety, phar
211 al enzyme endo-beta-N-acetylglucosaminidase (EndoS) induced a dominant suppression of immune complex
212 the critical combination of factors C4-(exo/endo), intraresidue H-bonding, stereoelectronic (R/S) an
216 human apurinic/apyrimidinic endonuclease (AP endo) is a major factor in the maintenance of the integr
219 ndoglycosidase from Streptococcus pyogenes , EndoS, is complementary to other known endoglycosidases
222 complex can easily escape from intracellular endo-/lyso-somal compartments and release the gene load
223 that PorB increases the level of OVA in the endo-/lysosomal cellular compartment of BMDCs, increases
224 ndergoes pH-dependent disassembly within the endo-/lysosomal compartment, thereby exposing hidden dom
228 ozygous TGF-beta receptor knockout (TbetaRII(endo+/-)) mice to explore whether curtailed TGF-beta sig
229 or unilateral ureteral obstruction, TbetaRII(endo+/-) mice exhibited less tubulointerstitial fibrosis
230 ndothelial cell-specific LKB1-knockout (LKB1(endo-/-)) mice by crossbreeding vascular endothelial-cad
232 nic folic acid-induced nephropathy) in Sirt1(endo-/-) mice resulted in robust acute renal functional
238 ablated the Tgf-beta type I receptor Alk5 in endo-, myo- and epicardial lineages using the Tie2-Cre,
241 ves which are biased toward a "Northern" (3'-endo, N) sugar ring pucker were deaminated up to 65-fold
243 ssary for the sugar pucker to adjust to a 3'-endo (N-type) conformation to remain in the ADA substrat
244 ve repuckering of the 5'-G sugar ring to C3'-endo (N-type) conformation, retention of C2'-endo (S-typ
245 d repuckering of the 5'-G sugar rings to C3'-endo (N-type), retention of C2'-endo (S-type) conformati
248 , in contrast to the previously reported C3'-endo (North conformation) described for the original 2.7
249 distinct sugar conformations by using a 3'- endo (north) 2'-fluoro-2'-deoxyribofuranosyl thymine (1)
250 he effect of monomer stereochemistry (exo vs endo) of two types of ester substituted monomers was als
251 xt/Endo), PDC with an Ext/Endo (PDC with Ext/Endo), or Ext/Endo without PDC (Ext/Endo without PDC).
252 hree classes of PBPs catalyze either trans-, endo-, or carboxypeptidase activities on the peptidoglyc
253 In this way, the molecule is converted to an endo- or an exoligand, possessing a concave or convex ar
255 These cationic 2-azadienes participate in endo- or exo-selective [4 + 2] cycloadditions with elect
256 pling of neuronal CB1Rs, after activation by endo- or exocannabinoids such as the marijuana component
258 spectrometry before and after treatment with endo- or exoglycosidases or with alkaline phosphatase.
260 d to reveal the substrate specificity of any endo- or exopeptidase using liquid chromatography-tandem
263 and/or endodontic treatment (PDC without Ext/Endo), PDC with an Ext/Endo (PDC with Ext/Endo), or Ext/
264 ment (PDC without Ext/Endo), PDC with an Ext/Endo (PDC with Ext/Endo), or Ext/Endo without PDC (Ext/E
265 radiation, leading to two regioisomeric (exo/endo) photoproducts with complete chemoselectivity (excl
266 rane whorls in both vacuoles and the sarco- (endo-) plasmic reticulum, findings suggestive of a toxic
269 llylic ring expansion to yield the formal "6-endo" products with aromatization via stereoelectronical
270 velopment of aromatic character along the "6-endo" reaction path is modulated via Au-complexation to
272 schemia deemed eligible for either Bypass or Endo, revascularization resulted in significant and clin
273 or the DNA-like C-2'-endo form over the C-3'-endo (RNA-like) conformation, which suggests a potential
275 endo (N-type) conformation, retention of C2'-endo (S-type) 3'-G sugar ring conformation, and anti ori
276 rings to C3'-endo (N-type), retention of C2'-endo (S-type) conformation for the 3'-G sugar rings, and
278 osphate receptor (IP3R), thereby linking the endo-/sarcoplasmic reticulum to the plasma membrane.
281 ation, these hosts can exchange an interior (endo) situated metal binding site for an exterior (exo)
282 o-2'-deoxyribofuranosyl thymine (1) or a 2'- endo (south) 2'-fluoro-2'-deoxyarabinofuranosyl thymine
285 ower in cells isolated from the endocardial (Endo) than the epicardial (Epi) surface of the LV wall.
286 al trial of recombinant human endostatin (rh-Endo) that examined potential surrogates for response to
287 are evaluated by comparing their energies (E(endo)) to the sum of their isolated components (E(inc) =
288 mpanying transitions between non-helical (C2-endo) to helical (C3-endo) conformations during formatio
290 these stress-associated signals induced the endo- to ecodormancy transition and growth competence.
295 to 95 %) and regioselectivities (5-exo vs. 6-endo) were achieved through catalyst control and sequent
296 es, the highest stereoselectivities (>or=89% endo) were observed with 5-methyl or 6-methyl substituen
298 nsient-state kinetics with purified human AP endo, which had been expressed in Escherichia coli.
299 pathogens, secretes a large endoglycosidase, EndoS, which removes carbohydrates in a highly specific
300 within plant microbiomes, i.e., endophytes ("endo" = within, "phyte" = plant), can significantly modi