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1 rimary role in acute responses to this toxic endobiotic.
2 protecting organisms from multiple xeno- and endobiotics.
3 he hydroxyls and primary amines of xeno- and endobiotics.
4 aged in the metabolism of numerous xeno- and endobiotics.
5 metabolic activation of both xenobiotics and endobiotics.
6 e uptake and secretion of cationic drugs and endobiotics.
7                          We investigated the endobiotic and hepatic role of AHR in fatty liver and en
8                 Mammalian systems inactivate endobiotic and xenobiotic compounds by linking them to a
9  P450 are versatile enzymes that function in endobiotic and xenobiotic metabolism and undergo meaning
10  receptor that regulates enzymes involved in endobiotic and xenobiotic metabolism.
11 n species, electrophiles, and other reactive endobiotic and xenobiotic metabolites.
12 ely involved in clearing potentially harmful endobiotic and xenobiotic OAs from the eye.
13 minate by glucuronidation a broad variety of endobiotic and xenobiotic substrates, which include bili
14 d by an impaired metabolic detoxification of endobiotics and a persistent microbial-induced immune re
15 for the metabolism and secretion of numerous endobiotics and drugs.
16 germ-free mice have reduced levels of active endobiotics and that distinct gut microbial Loop 1 and F
17 ontrol glucose production, detoxification of endobiotics and xenobiotics, and the regulation of prost
18 etion and lipophilicity) of a broad range of endobiotics and xenobiotics, which could plausibly have
19 nzyme involved in the metabolism of multiple endobiotics and xenobiotics.
20 hat catalyse the glucuronidation of numerous endobiotics and xenobiotics.
21 nt regulation of Tregs to maintain a healthy endobiotic balance.
22 ification and elimination of xenobiotics and endobiotics by modulating the expression of genes encodi
23  metabolism and excretion of xenobiotics and endobiotics by regulating the expression of drug-metabol
24 enosensors postulated to alleviate xeno- and endobiotic chemical insults.
25 zes a range of potentially harmful drugs and endobiotic chemicals but must complex with the nuclear r
26  the conjugation of lipophilic exobiotic and endobiotic compounds, which leads to the excretion of hy
27 abolism of a wide spectrum of xenobiotic and endobiotic compounds.
28 play a central role in processing a range of endobiotic compounds.
29 eptor (CAR) are implicated in xenobiotic and endobiotic detoxification, including the clearance of to
30                           Interestingly, the endobiotic estradiol-17-glucuronide and the xenobiotic i
31 xpel numerous chemically unrelated xeno- and endobiotics from cells.
32                    Our study thus reveals an endobiotic function of CYP1B1 in liver fibrosis in males
33             The differential reactivation of endobiotic glucuronides by gut microbial beta-glucuronid
34 ndrostane receptor (CAR) modulates xeno- and endobiotic hepatotoxicity by regulating detoxification p
35 ility of gut microbial enzymes in sustaining endobiotic homeostasis and indicate that therapeutic dis
36 re important in the elimination of xeno- and endobiotics, including the natural biladienone pigment b
37 ane X receptor (PXR) mediates xenobiotic and endobiotic metabolism as well as hepatocyte proliferatio
38  a physiological sensor in the modulation of endobiotic metabolism for hormones, bile acids, choleste
39  knowledge of PXR expression and its role in endobiotic metabolism related to MASH development, which
40 itical genes involved in both xenobiotic and endobiotic metabolism remain limited.
41 siological regulation of both xenobiotic and endobiotic metabolism.
42 xpression of genes central to xenobiotic and endobiotic metabolism.
43 and is involved in xenobiotic processing and endobiotic metabolism.
44 r (CAR) is a key regulator of xenobiotic and endobiotic metabolism.
45 g gene expression involved in xenobiotic and endobiotic metabolism.
46  immunomodulatory control by interactions of endobiotic metabolites with diet, microbiota and the imm
47 es P450 (P450s), are enzymes that metabolize endobiotics (physiologically active steroids and fatty a
48 uman carboxylesterase 1 (hCE1) is a drug and endobiotic-processing serine hydrolase that exhibits rel
49 oss-talk and the hierarchy of xenobiotic and endobiotic regulation.
50     In this study, we show that PXR plays an endobiotic role by impacting lipid homeostasis.
51  The goal of this study was to determine the endobiotic role of AhR in hepatic steatosis.
52  this study, we have uncovered an unexpected endobiotic role of PXR in obesity and type 2 diabetes.
53 response to potentially toxic xenobiotic and endobiotic stimuli.
54 or of coordinate responses to xenobiotic and endobiotic stress.
55 in the coordinate response to xenobiotic and endobiotic stress.
56 o conjugate xenobiotics, including drugs and endobiotics such as metabolic byproducts, hormones, and
57 epatic metabolism of therapeutics as well as endobiotics such as steroid hormones.
58 bile formation, intermediary metabolism, and endobiotic/xenobiotic detoxification.